| the noguchi-adler phenomenon: an ultrastructural study of the effects of homologous antiserum on the growth of promastigotes of leishmania braziliensis braziliensis and leishmania hertigi hertigi. | a light and electron microscope study was made of the agglutinated bodies formed on growing promastigotes of a leishmania b braziliensis and a l. h. hertigi strain in their homologous antisera to determine the role of leishmanial excreted factor (ef) in the noguchi-adler phenomenon, since the l. b. braziliensis strain produced a demonstrable ef, whereas the l. h. hertigi strain did not. promastigotes of l. b. braziliensis, when grown in high concentrations of homologous antiserum, formed noguchi ... | 1979 | 395912 |
| letter: metastatic spread of leishmania braziliensis braziliensis to the extremities of hamsters. | | 1976 | 1265829 |
| the action of oxamniquine on leishmania braziliensis braziliensis in hamsters. | | 1976 | 1273408 |
| leishmania braziliensis spp. in the nasal mucosa of guinea pigs inoculated in the tarsi. | two lots of 20 young male guinea pigs were inoculated subcutaneously in the tarsi with 10(4) amastigotes of leishmania braziliensis braziliensis or l. b. guyanensis to study the susceptibility of this neotropical hystricomorph rodent the autochthonous parasites. almost 50% of the animals showed lesions in the inoculation site and had parasitizations that were infective to hamsters, as shown by inoculating homogenates of the dermal lesion, of the spleen, of the liver, and of the nasal mucosa into ... | 1992 | 1308558 |
| disseminated american muco-cutaneous leishmaniasis caused by leishmania braziliensis braziliensis in a patient with aids: a case report. | the authors report a case of culture-proven disseminated american muco-cutaneous leishmaniasis caused by leishmania braziliensis braziliensis in an hiv positive patient. lesions began in the oropharynx and nasal mucosa eventually spreading to much of the skin surface. the response to a short course of glucantime therapy was good. | 1992 | 1343662 |
| isoenzyme characterization of leishmania braziliensis braziliensis isolates obtained from bolivian and peruvian patients. | thirty-four leishmania isolates obtained from bolivian and peruvian patients infected with mucocutaneous leishmaniasis were characterized by isoenzyme electrophoresis using 10 enzymatic markers; all belonged to the subspecies l.b. braziliensis. three isolates showed marked variation compared with the reference strain with respect to 5 or 6 enzymes. these variant isolates originated from patients with forms of the disease which were unresponsive to treatment. | 1992 | 1440812 |
| the 70-kda heat-shock protein is a major antigenic determinant in human trypanosoma cruzi/leishmania braziliensis braziliensis mixed infection. | five sera from bolivian individuals chronically infected by trypanosoma cruzi, and suffering an active leishmania braziliensis braziliensis metastatic mucocutaneous lesion were characterized. they reacted with the t. cruzi recombinant antigens that are currently used as chagas diagnostic reagents, and with several l. b. braziliensis proteins as assessed by western blot. these sera showed an intense reaction with a t. cruzi and an l. b. braziliensis polypeptide of about 70 kda. expression cloning ... | 1992 | 1548032 |
| [results of montenegro's reaction in patients with mucocutaneous leishmaniasis, from espírito santo state]. | the authors analysed the results of montenegro test in 402 patients with mucocutaneous leishmaniasis from espírito santo state, where the leishmania braziliensis braziliensis has been isolated from humans cases and dogs. the test was positive in 371 cases (92.2%) before treatment. the montenegro test given during or after treatment changed the results in 17 of 20 negative cases. the remaining 3 cases and 9 which changed the results had positives biopsies. it was demonstrated again the efficiency ... | 1991 | 1668537 |
| experimental american leishmaniasis and chagas' disease in the brazilian squirrel monkey: effect of dual infection on antibodies to parasite antigens. | adult, laboratory-bred squirrel monkeys (saimiri sciureus) were infected with either leishmania braziliensis braziliensis or l. b. panamensis and, 42 weeks later, they were challenge-infected with trypanosoma cruzi. another group of monkeys was infected with t. cruzi and challenged with l. b. braziliensis after 42 weeks. immunoblotting was used to examine parasite antigens bound by antibodies in plasma obtained from the monkeys during the course of primary and challenge infections. during primar ... | 1991 | 1743848 |
| comparison on the performance of leishmania major-like and leishmania braziliensis braziliensis as antigen for new world leishmaniasis igg-immunofluorescence test. | the performance of an antigen of l. major-like promastigotes for the serological diagnosis of mucocutaneous leishmaniasis in the igg-immunofluorescent test was compared to that of an antigen of l.braziliensis braziliensis. each antigen was used to test two hundred and twenty-four sera of etiologies such as mucocutaneous leishmaniasis, deep mycoses, toxoplasmosis, malaria. chagas' disease, visceral leishmaniasis, anti-nuclear factor, schistosomiasis, rheumatoid factor and normal controls. agreeme ... | 1991 | 1844982 |
| separation of psychodopygus carrerai carrerai and p. yucumensis (diptera: psychodidae) by gas chromatography of cuticular hydrocarbons. | specimens of two species of sandfly, psychodopygus carrerai carrerai and p. yucumensis, vectors of leishmania braziliensis braziliensis in the subandean lowlands of bolivia, were subjected to cuticular hydrocarbon analysis to ascertain if the technique could separate the females. a high degree of separation (87%) was obtained based on significant differences in the cuticular hydrocarbon composition of these two species. statistical treatment of the data shows that these species, initially identi ... | 1990 | 1971491 |
| a mouse model of leishmania braziliensis braziliensis infection produced by coinjection with sand fly saliva. | to development a reliable murine model of leishmania braziliensis braziliensis infection, parasites were injected into balb/c mice in the presence of phlebotomine sand fly salivary gland lysates, which have previously been shown to greatly increase the infectivity of l. major in mice. when injected with salivary gland lysates, l. braziliensis braziliensis produced progressively enlarging cutaneous nodules, containing many macrophages filled with leishmania amastigotes. in contrast, l. braziliens ... | 1991 | 1985126 |
| antigenic specificity of the 72-kilodalton major surface glycoprotein of leishmania braziliensis braziliensis. | we examined the expression and the antigenicity of the major surface polypeptides of leishmania braziliensis braziliensis and leishmania donovani chagasi, parasites which commonly coexist in the same endemic areas of bolivia. sodium dodecyl sulfate-polyacrylamide gel electrophoresis protein profiles from surface-iodinated promastigotes showed the presence of a unique iodinatable polypeptide of 72 kda on the l. b. braziliensis surface and of two major components of 65 and 50 kda exposed at the su ... | 1991 | 2037677 |
| identification of cytoplasmic soluble antigens related to the major surface antigens of leishmania braziliensis braziliensis and l. donovani chagasi. | this study describes the identification of aqueous-soluble antigens in leishmania promastigotes immunologically and biochemically closely related to the major surface antigen. proteins from surface-iodinated l. braziliensis braziliensis and l. donovani chagasi promastigotes, extracted and separated by partitioning in the detergent triton x-114, were analyzed. immunoblotting of the extracted proteins, using homologous antisera, showed recognition of a 72-kda labeled, amphiphilic antigen of l. b. ... | 1990 | 2179945 |
| quantitative study of leishmania braziliensis braziliensis reactive t cells in peripheral blood and in the lesions of patients with american mucocutaneous leishmaniasis. | a limiting dilution analysis (lda) was utilized to estimate the frequency of l. braziliensis braziliensis reactive t cells (lbb-t cells) in peripheral blood and in the lesions of patients with mild localized cutaneous leishmaniasis (lcl) or with severe mucosal leishmaniasis (mcl). the frequencies of lbb-t cells in peripheral blood varied from 1:107300 to 1:3587 and were not significantly different in mcl and lcl patients. however, a significant difference was encountered (p less than 0.02) betwe ... | 1990 | 2311299 |
| placebo-controlled clinical trial of meglumine antimonate (glucantime) vs. localized controlled heat in the treatment of cutaneous leishmaniasis in guatemala. | sixty-six guatemalans with parasitologically proven cutaneous leishmaniasis were randomly and equally divided into 3 treatment groups: those receiving meglumine antimonate (glucantime), 850 mg antimony/day im for 15 days; those receiving localized controlled heat from a radio-frequency generator, 50 degrees c for 30 sec, 3 treatments at 7 day intervals; and those receiving treatment with a placebo. of 53 isolates identified, 40 were leishmania braziliensis braziliensis and 13 were l. mexicana me ... | 1990 | 2405727 |
| active transmission of leishmania braziliensis braziliensis in the serra de mar forest, são paulo, brazil. | | 1989 | 2609369 |
| analysis of the specificity of human antibodies to antigens of leishmania braziliensis braziliensis. | the antigenicity of promastigotes of leishmania braziliensis braziliensis (l. b. braziliensis) treated with 1% sodium desoxycholate in 10 mm tris-hcl ph 8.2 was analysed by immunoblot using as probes sera from american cutaneous leishmaniasis (acl), american visceral leishmaniasis (avl), schistosomiasis, malaria and chagas' disease. the acl sera reacted constantly with a 60 kd band. no reactivity to this protein was observed with sera from the other diseases above mentioned indicating that the 6 ... | 1989 | 2626643 |
| [an attempt to treat skin ulcer caused by leishmania braziliensis braziliensis with ketoconazole]. | | 1989 | 2638483 |
| mucosal leishmaniasis in brazil. | the clinical diagnosis and laboratory identification of leishmania braziliensis braziliensis, a parasitic disease affecting the upper aerodigestive tract, is difficult. a retrospective computer-assisted analysis of patient records was done after examination of 58 patients with mucosal leishmaniasis in an endemic area of l. braziliensis braziliensis in bahia, brazil during january 1987. biopsies of clinically active and clinically inactive mucosal patients were examined for parasites using routin ... | 1989 | 2671555 |
| experimental canine mucocutaneous leishmaniasis (leishmania braziliensis braziliensis). | four mongrel dogs were intradermically inoculated with 3 x 10(6) leishmania braziliensis braziliensis promastigotes. three out of the four animals developed cutaneous lesions respectively 4, 7, and 8 months after. the fourth dog did not develop lesion at the inoculation site, but a mucosal ulcer was seen 16 months after the inoculum. clinical, histopathological, and serological findings were similar to what is found in natural canine infection as well as in the human disease. these results sugge ... | 1988 | 2687621 |
| topical pentostam in an attempt to produce more rapid healing of skin ulcers due to leishmania braziliensis braziliensis. | | 1986 | 2825253 |
| separation of female psychodopygus wellcomei and p. complexus (diptera: psychodidae) by cuticular hydrocarbon analysis. | psychodopygus wellcomei (diptera: psychodidae), vector of leishmania braziliensis braziliensis - causative agent of cutaneous leishmaniasis in brazil, cannot be distinguished from sympatric p. complexus either by morphometrics or isoenzyme profiles. we report here the use of cuticular hydrocarbon analysis in the successful separation of individual female p. wellcomei and p. complexus. this technique involves the use of gas liquid chromatography and discriminant function analysis. | 1986 | 2872790 |
| high continuous antimony therapy in two patients with unresponsive mucosal leishmaniasis. | the treatment of two patients with severe mucosal leishmaniasis due to leishmania braziliensis braziliensis is described. both patients had received much prior antimonial therapy and one had relapsed after a total dose of 2.5 g of amphotericin b. both patients responded to prolonged continuous pentostam therapy at a daily dose of 20 mg sbv/kg/day for 62 days in one case and for 85 days in the other. pentavalent antimonials can be curative in such protracted courses in selected patients unrespons ... | 1985 | 2992304 |
| mucosal leishmaniasis ("espundia" escomel, 1911). | one of the more serious clinical forms of leishmaniasis occurs in espundia when the mucosae of the upper respiratory passages are inflamed. this complication is a metastasis from a skin lesion caused by leishmania braziliensis braziliensis (lbb) although cases have been described associated with other leishmanial species. epidemiological data suggest that a detectable mucosal metastasis occurs in fewer than 5% of patients infected with lbb in our study area. the determinants of this complication ... | 1986 | 3037735 |
| growth curves of leishmania braziliensis braziliensis promastigotes and surface antigen expression before and after adaptation to schneider's drosophila medium as assessed by anti-leishmania human sera. | | 1988 | 3059439 |
| indirect immunofluorescence test in new world leishmaniasis: serological and clinical relationship. | the indirect immunofluorescence test (if) for anti-leishmania antibodies (igg and igm) was performed with sera from the following groups of individuals: 214 cutaneous leishmaniasis patients, 28 healthy subjects with positive montenegro's skin test (mst), 29 healthy subjects with negative mst and 16 visceral leishmaniasis patients. the first four groups came from a suburban area of rio de janeiro (jacarepaguá) where cutaneous leishmaniasis caused by leishmania braziliensis braziliensis is endemic ... | 1988 | 3078345 |
| [preliminary results in favor of the existence of a major surface antigen, specific for leishmania braziliensis braziliensis]. | the comparative surface antigen study of 10 bolivian strains and 1 brazilian reference strain from l. b. braziliensis sub-species shows an important homogeneity within this group. all the strains tested so far present similar antigenic patterns with a major antigen at 72 kd. on the contrary, the comparative analysis of surface antigens of l. b. braziliensis with those of l. b. guyanensis, l. b. panamensis, l. mexicana amazonensis and l. donovani chagasi shows a large antigenic heterogeneity betw ... | 1986 | 3099979 |
| leishmania braziliensis braziliensis isolated from akodon arviculoides captured in caratinga, minas gerais, brazil. | | 1988 | 3176154 |
| predominance of leishmania braziliensis braziliensis in the regions of três braços and corte de pedra, bahia, brazil. | | 1988 | 3232172 |
| cutaneous leishmaniasis from guatemala or yucatan due to leishmania braziliensis braziliensis. | | 1988 | 3235257 |
| identification and purification of a 72 kda antigen of leishmania braziliensis braziliensis present on the surface and in the cytoplasm of the promastigotes and its specific recognition by sera from mucocutaneous leishmaniasis patients. | | 1988 | 3253506 |
| quantification of leishmania-specific t cells in human american cutaneous leishmaniasis (leishmania braziliensis braziliensis) by limiting dilution analysis. | limiting dilution analysis was used to estimate the frequency of leishmania-specific t cells from the peripheral blood of 18 human cases of american cutaneous leishmaniasis (acl). sixteen patients had localized cutaneous leishmaniasis (lcl) and two were recovered lcl patients. in 10 patients with active disease and in two with healed lesions the leishmania-specific t cell frequencies ranged from 1/10(5) to 1/10(3). in six patients no proliferation was detected after 21 days of cell culture. this ... | 1988 | 3258203 |
| an outbreak of american cutaneous leishmaniasis (leishmania braziliensis braziliensis) in a periurban area of rio de janeiro city, brazil: clinical and epidemiological studies. | from july 1984 to september 1986, 105 cases of american cutaneous leishmaniasis were studied in a locality closely situated to an urbanized area of the city of rio de janeiro, brazil. settlement in this area was established at least 20 years ago but the first cases were noted six months prior to the beginning of this study. cases were almost exclusively cutaneous and ulcerated, with one to six months of evolution. montenegro's skin tests were positive in all cases and anti-leishmania antibodies ... | 1988 | 3271941 |
| canine american cutaneous leishmaniasis: a clinical and immunological study in dogs naturally infected with leishmania braziliensis braziliensis in an endemic area of rio de janeiro, brazil. | clinical and immunological findings from 35 dogs infected with leishmania braziliensis braziliensis are described. the majority of the dogs had ulcerated single lesions on the ears. sera from all infected dogs showed detectable leishmania-induced antibodies using an indirect fluorescent antibody test. antimonial therapy resulted in prompt healing of the lesions in 80.9% of the animals followed by a significant reduction in the anti-leishmania antibody titers. however, treatment follow-up showed ... | 1988 | 3277465 |
| [histopathology of tegumentary leishmaniasis caused by leishmania braziliensis braziliensis. 2. tissue humoral response]. | | 1986 | 3296117 |
| generation of leishmania-specific short-term t-cell lines derived from peripheral blood of cured american cutaneous leishmaniasis patients. | the putative protective immune response in localized cutaneous leishmaniasis caused by leishmania braziliensis braziliensis (lbb) was analysed by generation of short term t-cell lines from peripheral blood lymphocytes (pbl) of three patients. all had had active skin lesions but were clinically cured at the time of study. pbl were stimulated in vitro with sonicated lbb promastigotes; blasts were isolated after 5 days and propagated for 9 to 16 days before being tested for proliferative capacity. ... | 1987 | 3314910 |
| cutaneous leishmaniasis in guatemala: isoenzyme characterization of isolates from humans. | leishmania organisms cultivated from cutaneous lesions of humans in guatemala were characterized by cellulose acetate electrophoresis. six isolates had electrophoretic enzyme patterns identical to world health organization reference strains of leishmania braziliensis braziliensis, and 5 had patterns identical to reference strains of leishmania mexicana mexicana. | 1988 | 3341522 |
| [the in vitro culture method as a practical instrument in the diagnosis and primary isolation of leishmania braziliensis braziliensis. i. laboratory observations]. | | 1986 | 3432628 |
| leishmaniasis in brazil: xxiii. the identification of leishmania braziliensis braziliensis in wild-caught neotropical sandflies using monoclonal antibodies. | using the indirect immunofluorescence test natural flagellate infections of wild-caught sandflies, from the serra dos carajás region of pará state, brazil, were identified by sequentially staining smears made from the infected flies with monoclonal antibodies. with normal methods of isolation 30% of the infections were identifiable, but when monoclonal antibodies specific to leishmania braziliensis braziliensis were used a further 26% were identified. the staining of organisms in smears of natur ... | 1987 | 3445325 |
| spontaneous healing of cutaneous leishmania braziliensis braziliensis ulcers. | | 1987 | 3445344 |
| cutaneous leishmaniasis in bolivia. a study of 185 human cases from alto beni (la paz department). isolation and isoenzyme characterization of 26 strains of leishmania braziliensis braziliensis [corrected]. | a clinical, serological, parasitological and therapeutic study of cutaneous leishmaniasis was carried out in a low sub-andean area (250-800 metres) of the la paz department, bolivia. a team of seismic prospectors (350 workers) was surveyed for 12 months. of 200 suspected cases of cutaneous leishmaniasis, 185 were serologically or parasitologically confirmed (incidence 52.8%). those exposed to the greatest risk of infection were working in a virgin forest environment. leishmanial organisms were i ... | 1987 | 3449990 |
| human, canine and equine leishmaniasis caused by leishmania braziliensis braziliensis in an endemic area in the state of rio de janeiro. | | 1987 | 3507562 |
| [isolation and identification of leishmania braziliensis braziliensis, in human cases and domestic dog, in the state of são paulo]. | | 1986 | 3509356 |
| [histopathology of cutaneous leishmaniasis by leishmania braziliensis braziliensis. 1. histopathological patterns and study of the course of the lesions]. | | 1986 | 3563308 |
| leishmaniasis in bolivia. ii. the involvement of psychodopygus yucumensis and psychodopygus llanosmartinsi in the selvatic transmission cycle of leishmania braziliensis braziliensis in a lowland subandean region. | an epidemiological survey of the vectors of cutaneous leishmaniasis ("espúndia" type) was carried out in the alto beni region of bolivia, an area of andean foothills at the eastern limit of the amazonian lowlands. the climate is typical wet tropical (15 degrees s latitude). anthropophilic phlebotomine sandfly species were sampled at 20 sites, all forested. the importance of species from the psychodopygus group, already suspected as a vector in the transmission of leishmania from the braziliensis ... | 1986 | 3574129 |
| [natural infection of equus asinus by leishmania braziliensis braziliensis-bahia, brazil]. | in corte de pedra, valença, state of bahia, a donkey, equus asinus, was found naturally infected with leishmania braziliensis braziliensis. the parasite was isolated from a lesion located on a castration scar, and identified by means of monoclonal antibodies. | 1986 | 3587004 |
| [histopathology of tegumentary leishmaniasis caused by leishmania braziliensis braziliensis. 3. cellular reactions in tissues]. | | 1986 | 3589392 |
| [in vitro culture as a practical tool for the diagnosis and primary isolation of leishmania braziliensis braziliensis. 2. studies in patients in endemic areas]. | | 1986 | 3589393 |
| epidemiology of american cutaneous leishmaniasis due to leishmania braziliensis braziliensis. | a five-year prospective study of cutaneous leishmaniasis in an endemic area of brazil revealed an annual incidence of disease of 8.1 per 1000 inhabitants and a prevalence of 14.9%. the disease fluctuated as a series of mini-epidemics. most disease occurred in individuals who were 10-30 years of age. mucosal disease occurred in 2.7% of patients with primary lesions and occurred a median of six years after this lesion. disease was more common in males, in those with either large or multiple antece ... | 1987 | 3598227 |
| [histopathology of cutaneous leishmaniasis caused by leishmania braziliensis braziliensis. 4. histopathological classification]. | | 1986 | 3602829 |
| experimental american leishmaniasis in the brazilian squirrel monkey (saimiri sciureus): lesions, hematology, cellular, and humoral immune responses. | unulcerated cutaneous lesions appeared and persisted in squirrel monkeys experimentally infected with leishmania braziliensis braziliensis or l. b. panamensis. peripheral blood mononuclear cell (pbmc) numbers increased following infection, and cultured pbmcs from infected monkeys proliferated in response to parasite antigens. the responses of pbmcs to mitogens were not suppressed in infected monkeys. elevated levels of leishmania-specific immunoglobulins m and g were also observed. thus, the squ ... | 1987 | 3612761 |
| identification of a major 72 kilodalton surface antigen in twelve isolates of leishmania braziliensis braziliensis. | the study of the surface antigens of leishmania braziliensis braziliensis revealed a great homogeneity among ten strains isolated from bolivia and two reference strains from brazil and belize. a 72 kda major protein, present in all l. b. braziliensis strains, was recognized by both cutaneous and mucocutaneous human sera, but was not recognized by kala-azar and chagasic sera. no cross-reactive antigens were found among strains of leishmania braziliensis guyanensis, leishmania braziliensis panamen ... | 1987 | 3627165 |
| concurrent human infection with leishmania donovani and leishmania braziliensis braziliensis. | in the suburban district of campo grande, municipality of rio de janeiro (brazil) cases of both leishmania domovani and l. b. braziliensis infections occur. in march 1982 we examined a white male child, five years old, with fever, weight loss and distended abdomen, symptoms said to have started three months before. after the first month a papular lesion appeared on his forehead, rapidly increasing in size and becoming ulcerated: parasites were isolated from both the ulcer and the bone marrow by ... | 1986 | 3675032 |
| leishmaniasis in brazil. xxiv. natural flagellate infections of sandflies (diptera: psychodidae) in pará state, with particular reference to the rôle of psychodopygus wellcomei as the vector of leishmania braziliensis braziliensis in the serra dos carajás. | between july 1983 and december 1984 natural flagellate infections were found in 114 (1%) of 11,586 female phlebotomine sandflies (diptera: psychodidae) of 21 species. a further 1084 females of 17 other species were not infected. identification of the organisms on a number of occasions confirms the exclusive parasite/vector relationship of leishmania mexicana amazonensis/lutzomyia flaviscutellata and le. braziliensis braziliensis/psychodopygus "wellcomei". undescribed or unidentified leishmania s ... | 1987 | 3686628 |
| three-dimensional reconstructions of the mitotic spindle and dense plaques in three species of leishmania. | the ultrastructure of the mitotic nucleus in leishmania braziliensis braziliensis, l. mexicana and l. donovani was studied by serial thin sections and three-dimensional reconstructions of each divisional stage. the structures of the interphase and four stages of dividing nuclei were described. attention was paid to dense plaques and spindle microtubules. at the beginning of the nuclear division, a set of six dense plaques was found in association with spindle microtubules in the vicinity of the ... | 1986 | 3716540 |
| intralesional glucantime in leishmania braziliensis braziliensis infections. | | 1986 | 3726989 |
| failure to detect circulating leishmania in mucocutaneous leishmaniasis due to leishmania braziliensis braziliensis. | | 1986 | 3787695 |
| [experimental infection of lutzomyia whitmani in dogs infected with leishmania braziliensis braziliensis]. | lutzomyia (n.) whitmani was infected on leishmaniotic lesions of three out of nine dogs infected with leishmania braziliensis braziliensis. the infectivity rates in these sandflies were 8.3% (1/12), 7.1% (1/14) and 1.8% (3/160), respectively. in addition, 180 lu. whitmani fed on non-ulcerated regions of one of the infected dogs and none became infected. we emphasize the vector potentiality of lu. whitmani for l.b. braziliensis in the endemic region of três braços, bahia, brazil. | 1986 | 3796276 |
| cultivation of leishmania braziliensis braziliensis from skin ulcers in man under field conditions. | | 1986 | 3798543 |
| disseminated cutaneous leishmaniasis in a field clinic in bahia, brazil: a report of eight cases. | eight bahian patients with cutaneous leishmaniasis who had 20 or more ulcerative lesions of short duration are described. of five identifications of isolated parasites, four were leishmania braziliensis braziliensis and one was l. mexicana amazonensis. all but one had positive montenegro tests initially, and all did after treatment. all had circulating anti-leishmanial antibodies and five responded well to glucantime therapy suggesting a functioning immune response. this is quite different to th ... | 1986 | 3806749 |
| a survey for american cutaneous and visceral leishmaniasis among 1,342 dogs from areas in rio de janeiro (brazil) where the human diseases occur. | there are areas in the periphery of rio de janeiro city where human cases of visceral and/or cutaneous leishmaniasis occur. the parasites have been identified as leishmania donovani and leishmania braziliensis braziliensis respectively. a survey for leishmaniasis was done among 1,342 dogs from those areas using an indirect immunofluorescent test. from the dogs, 616 came from areas where only human cases of visceral leishmaniasis occurred, 373 from an area where all human cases were of cutaneous ... | 1985 | 3910994 |
| leishmania braziliensis braziliensis infection of the nipple. | | 1985 | 3918617 |
| mucocutaneous leishmaniasis in colombia: leishmania braziliensis subspecies diversity. | it is generally held that with rare exception leishmania braziliensis braziliensis is the parasite responsible for the metastatic development of mucocutaneous leishmaniasis in the new world. yet the infrequency of mucocutaneous disease compared with cutaneous manifestations, and the difficulty of isolating parasites from mucocutaneous lesions have restricted the study of the organisms involved. we here report the biologic, isoenzymatic, and monoclonal antibody specificity characteristic of eight ... | 1985 | 4025684 |
| allopurinol treatment in human leishmania braziliensis braziliensis infections. | | 1984 | 6464145 |
| spontaneous healing of leishmania braziliensis braziliensis skin ulcers. | | 1984 | 6485067 |
| allopurinol treatment in human leishmania braziliensis braziliensis infections. | | 1984 | 6506163 |
| clinical characteristics of human leishmania braziliensis braziliensis infections. | | 1984 | 6533860 |
| presence of psychodopygus wellcomei (diptera: psychodidae), a proven vector of leishmania braziliensis braziliensis, in ceará state. | | 1983 | 6645954 |
| the isolation and isoenzyme characterization of leishmania braziliensis subsp. from patients with cutaneous leishmaniasis acquired in belize. | leishmanial organisms were cultivated from cutaneous lesions of british military personnel returning from belize. isoenzyme profiles of the freshly isolated organisms and 'marker' strains of new world leishmania spp. were compared using 10 enzymes (alat, asat, me, gpi, mpi, pgm, sod, 6-pgdh, g-6-pdh and mdh), by starch gel electrophoresis. 19 of the 22 new isolates from belize were isoenzymically indistinguishable from leishmania braziliensis braziliensis (10 out of 10 enzymes) and clearly diffe ... | 1984 | 6710574 |
| a laboratory infection with leishmania braziliensis braziliensis. | | 1983 | 6868110 |
| leishmaniasis in brazil: xvii. enzymic characterization of a leishmania from the armadillo, dasypus novemcinctus (edentata), from pará state. | a comparison of enzyme profiles, by starch-gel electrophoresis, has distinguished a leishmania of armadillos (dasypus novemcinctus), from pará state, north brazil, from leishmania braziliensis braziliensis, l. braziliensis guyanensis, l. mexicana amazonensis, l. donovani sensu lato (from bahia, brazil), and l. hertigi deanei. the parasite was separated from l. b. braziliensis and l. b. guyanensis by 8 of the 14 enzymes used (asat, alat, pgm, gpi, g6pd, pep, mpi and gd), although differences in t ... | 1982 | 7164148 |
| leishmania braziliensis braziliensis: metastatic infection in a golden hamster. | | 1980 | 7210144 |
| cutaneous leishmaniasis in british troops from belize. | the medical records of 306 british soldiers in whom a clinical diagnosis of cutaneous leishmaniasis had been made following a tour of duty in belize were analysed. parasitological confirmation of the diagnosis was established in 187 cases; leishmania were cultured in 117 cases and leishman-donovan bodies were identified histologically in a further 70 cases. leishmania braziliensis braziliensis was identified in 78 cases and leishmania mexicana mexicana in a further 29 cases. seventy-one per cent ... | 1993 | 8381299 |
| clinical presentations of leishmania braziliensis braziliensis. | leishmania braziliensis braziliensis (lbb) is probably the most serious, leishmanial infection of the new world. although epidemiological information is incomplete, its distribution is believed to extend from belize in central america to northern argentina, involving all countries east of the andes. lbb causes a variety of clinical lesions and is one of the most difficult forms of leishmaniasis to treat. we still do not know how many patients suffer from mucosal disease requiring treatment. in t ... | 1985 | 15275583 |
| leishmania parasites (kinetoplastida: trypanosomatidae) reversibly inhibit visceral muscle contractions in hemimetabolous and holometabolous insects. | female sand flies can acquire protozoan parasites in the genus leishmania when feeding on an infected vertebrate host. the parasites complete a complex growth cycle in the sand fly gut until they are transmitted by bite to another host. recently, a myoinhibitory peptide was isolated from leishmania major promastigotes. this peptide caused significant gut distension and reversible, dose-dependent inhibition of spontaneous hindgut contractions in the enzootic sand fly vector, phlebotomus papatasi. ... | 2004 | 15579321 |
| isolation of leishmania (viannia) braziliensis from lutzomyia spinicrassa (species group verrucarum) morales osorno mesa, osorno and hoyos 1969, in the venezuelan andean region. | natural infection with leishmania spp. in phlebotomine sandflies was searched for during a longitudinal study carried out from july 1997 to july 1998 in the village catarnica, municipality independencia, táchira state. this hamlet is an old endemic focus of cutaneous leishmaniasis in the venezuelan andean region, which lies close to the colombian border at 1,300 m a.s.l., in an agricultural area mainly used for cultivating coffee. phlebotomine sandflies were collected using shannon traps placed ... | 2006 | 16605063 |