| [antibodies in rhesus-monkeys after experimental infection with african lung-worms (paragonimus uterobilateralis and p. africanus) (author's transl)]. | the following publication gives a report about serological studies on experimentally infected macaca mulatta with paragonimus uterobilateralis and p. africanus supplied by parasitological findings and chest x-ray experiments from other authors. it was shown that at first in the chronological sequence serological changes were noticed in the animals followed by x-ray changes of the lungs. somewhat later the monkeys started with the excretion of worm-eggs. egg production did not take place in all m ... | 1977 | 414393 |
| intestinal parasites of school children in urban and rural areas of eastern nigeria. | from october 1975 to march 1976 an epidemiological survey was carried out in anambra and imo states of nigeria to determine the rate of intestinal worm and protozoan infections in school children. a total of 1742 children, out of which 813 from the urban and 929 from the rural school were screened of intestinal helminths and 1699 were also examined for intestinal protozoan infections. concentration methods hcl-ether centrifugation technique and heidenhain's iron-hematoxylin staining method respe ... | 1978 | 735552 |
| single dose therapy of paragonimiasis with menichlopholan. | menichlopholan, biphenyl compound, in a single dose of 2 mg/kg body weight, gave a 73%-90% cure rate in the treatment of pulmonary infections due to paragonimus uterobilateralis at two centers in nigeria. ninety-five patients were followed up for 4 months, and 58 for 1 year. side effects of the drug included sweating and body pains, but there was no significnat biochemical or hematological evidence of damage to the internal organs. the advantages of single dose therapy are likely to make menichl ... | 1977 | 889010 |
| first record of the spiny river crab, liberonautes chaperi (a. milne-edwards 1887), as second intermediate host of paragonimus uterobilateralis in liberia. | | 1991 | 1796892 |
| the dwarf river crab liberonautes latidactylus nanoides cumberlidge & sachs, 1989, from liberia--a new second intermediate host of paragonimus uterobilateralis. | large populations of the dwarf river crab liberonautes latidactylus nanoides cumberlidge & sachs, 1989, collected from the st. paul river at the haindi/mauwa focus of paragonimiasis in liberia were examined for parasitization by the human lung fluke, paragonimus uterobilateralis. four specimens out of 763 l. l. nanoides proved to be positive for p. uterobilateralis (0.52%), and each of these specimens contained only 1 metacercaria. the dwarf river crab forms the basis of a seasonal commercial fi ... | 1991 | 2052862 |
| distribution of metacercariae in freshwater crabs in relation to paragonimus infection of children in liberia, west africa. | an explanation was sought for the high prevalence of paragonimiasis in children in liberia by examining possible modes of human infection from freshwater crabs. the occurrence, frequency of infection, and distribution of metacercariae of paragonimus uterobilateralis in the freshwater crab liberonautes latidactylus were studied. the muscles of the cephalothorax and of the legs were found to be the most frequently and most heavily infected parts of the crab. a likely risk of infection of children ... | 1990 | 2222029 |
| the dog as natural reservoir host for paragonimus uterobilateralis in liberia, west africa. | | 1990 | 2331173 |
| the fine structure of the body wall of adult paragonimus uterobilateralis. | the body wall of adult paragonimus uterobilateralis was investigated by electron microscopy. the syncytial tegument contains prominent spines, mitochondria and disc-shaped granules. the apical surface forms ridges and pits, the basal membrane forms a conspicuous labyrinth. a layer of interstitial material with muscle fibres separates the syncytium from the parenchyme. the muscle fibres are organized in a transverse and a longitudinal layer and single radial fibres. thick and thin myofilaments do ... | 1989 | 2623424 |
| clinical field trials of praziquantel in pulmonary paragonimiasis due to paragonimus uterobilateralis in endemic populations of the igwun basin, nigeria. | a clinical field trial of praziquantel was carried out on patients infected with paragonimus uterobilateralis in the igwun basin, nigeria. 332 patients were subjected to the praziquantel therapy. 290 (87.3%) reverted to negative status. the pattern of reduction in sputum and faecal egg counts was related to the quantity of praziquantel administered. with 45 mg daily dose reduction in sputum egg counts ranged from 83.2% to 87.3% with reversion rate of 71.1%; with 60 mg daily dose, 84.8-88.3% redu ... | 1989 | 2662354 |
| isolation of microcercous cercariae from snails caught in an endemic focus of paragonimus uterobilateralis in liberia, west africa. | microcercous cercariae have been recovered from the snail homorus (striosubulina) striatella rang. which were collected in a focus of human lung fluke disease in liberia, west africa, and are here described. metacercariae of paragonimus uterobilateralis were isolated from freshwater crabs (liberonautes latidactylus) captured at the same location, and at the same time, as the infected snails. the dimensions of the liberian cercariae have been found to differ markedly from those of a cercaria from ... | 1989 | 2740730 |
| the effects of triclabendazole on the lung fluke, paragonimus uterobilateralis in the experimental host sigmodon hispidus. | the new veterinary drug triclabendazole (fasinex) was tested for its anthelmintic activity against adult paragonimus uterobilateralis in experimentally infected cotton rats, sigmodon hispidus. after a single dose of 50, 100 or 150 mg/kg b.w. triclabendazole or after two doses of 5 or 10 mg/kg b.w. given at an interval of 24 hours, 56-61% of the flukes were dead at three to five weeks after treatment. two doses of 50 or 75 mg/kg b.w. triclabendazole killed all flukes. the flukes, which were still ... | 1988 | 3067323 |
| effects of the two new anthelmintic agents cgp 6140 and cgp 20376 on adult paragonimus uterobilateralis in the experimental host sigmodon hispidus. | the new compounds cgp 6140 and cgp 20376 were tested for their anthelmintic activity against adult paragonimus uterobilateralis in experimentally infected sigmodon hispidus. both drugs were effective at a dosage of 2 x 100 mg/kg b.w. given orally with an interval of six hours between the doses. this regimen killed 80% of the flukes collected on days 7 and 11 after treatment with cgp 6140 and 100% of the flukes collected on days 5, 7, and 11 after therapy with cgp 20376. both compounds showed no ... | 1987 | 3327145 |
| isoenzymes of the lung fluke paragonimus uterobilateralis from liberia. | the enzymes of 35 adult paragonimus uterobilateralis were analysed using thin-layer starch gel electrophoresis. from a total of 21 enzyme systems studied, 15 proved to be useful for the description and recognition of this species. all individuals were identical concerning 11 enzymes. in four remaining enzymes, alanine aminotransferase (alat, hexokinase, aspartate aminotransferase and phosphogluconate dehydrogenase, two or three variants, also being partly typical for this species were observed. ... | 1987 | 3441738 |
| prevalence of paragonimus uterobilateralis infection in children in a liberian village. | stool and sputum samples from 127 children in an endemic paragonimiasis area in liberia, west africa, were examined for the presence of lung fluke eggs. samples from nine children (7%) were positive. the eggs were identified as those of paragonimus uterobilateralis. | 1986 | 3603619 |
| endemic paragonimus infection in upper igwun basin, nigeria: a preliminary report on a renewed outbreak. | in a 24-month longitudinal study on a renewed outbreak of paragonimus infection in igwun basin, nigeria 1973 individuals were examined. a total of 332 (16.8%) individuals were found infected with paragonimus uterobilateralis. there was evidence of increasing annual prevalence rates from 15.0% in 1983 to 16.7% in 1984, and 18.7% in 1985. infection was present in all age groups, with prevalence of 18.9% in males and 14.5% in females. 12.3% of the infections were of high intensity, over 100 eggs in ... | 1987 | 3675045 |
| morphology of the lung fluke paragonimus uterobilateralis occurring in gabon, west africa. | the morphology of two adult lung flukes and eggs obtained from an experimentally infected cat in gabon corresponded in almost all details with the type material of paragonimus uterobilateralis. the taxonomic differences between these lung flukes and the type material of p. africanus are summarized. the zoogeography of west african paragonimus species is discussed. | 1985 | 4089475 |
| [morphological-taxonomical studies on paragonimus uterobilateralis (trematoda, troglotrematidae) as well as observations of the life cycle and the spread of the parasite in liberia]. | | 1973 | 4200242 |
| discovery of adult parasites of paragonimus uterobilateralis in human tissue in nigeria. | | 1974 | 4280638 |
| endemic paragonimiasis in africa. | human paragonimiasis has been recorded in 4 west african countries but there is clear evidence of endemicity only in certain parts of nigeria and cameroon. in nigeria, the dominant parasite species is paragonimus uterobilateralis, while in cameroon it is p. africanus. both the fresh water crab sudanonautes africanus and the land crab s. aubryi are proved vectors in nigeria. epidemiological studies using paragonimus skin tests suggest an infection rate of between 5% and 10% in some endemic areas. ... | 1974 | 4549201 |
| human paragonimiasis in eastern nigeria caused by paragonimus uterobilateralis. | | 1973 | 4744219 |
| [2 new paragonimus species from west africa: paragonimus africanus and paragonimus uterobilateralis (troglotrematidae; trematoda)]. | | 1965 | 4954791 |
| [paragonimiasis in black africa. a recent infection focus in ivory coast]. | the authors recapitulate in short the distribution of paragonimiasis in west africa. they establish and show keys for determination of adults and eggs of the agents of the disease (paragonimus uterobilateralis, p. africanus, poikilorchis congolensis). the first intermediate host is unknown but two species of snails are suspected (afropomus balanoides, potadoma sanctipauli). a very abundant crab (liberonautes latidactylus) seems to be the second intermediate host. | 1980 | 6257410 |
| successful treatment with praziquantel of six patients infected with the african lung fluke, paragonimus uterobilateralis. | six cases of human paragonimiasis (paragonimus uterobilateralis) are documented from liberia and guinea. these are the first cases reported from these countries. paragonimiasis should be considered in the differential diagnosis of any west african patient who presents with hemoptysis. praziquantel was used successfully to treat these patients, and may be the drug of choice for p. uterobilateralis infections. | 1983 | 6837846 |
| [paragonimus uterobilateralis as the cause of 3 cases of human paragonimiasis in gabon]. | during 1981, three cases of pulmonary paragonimiasis were diagnosed and successfully treated at the albert schweitzer hospital, lambarene, gabon. circumstances prevented our receiving eggs for identification of the lung fluke species involved. the history revealed that all the patients originated from the same small village mitoné, some 10 km north of lambarene. extensive testing in the region failed to reveal further cases. our efforts, therefore, were concentrated on the study of the intermedi ... | 1983 | 6879703 |
| human paragonimiasis caused by paragonimus uterobilateralis in liberia and guinea, west africa. | in the children from liberia and one woman from guinea an infection with the lung fluke paragonimus uterobilateralis was diagnosed, being the first cases of human paragonimiasis recorded in these two west african countries. species determination was based on measurements and morphological structure of the parasite ova isolated from sputum and stool of the patients, and supported by biological and epidemiological evidence of the occurrence of this parasite species in natural animal hosts and p. u ... | 1982 | 7101436 |
| epidemiology of paragonimiasis in cross river basin, nigeria: prevalence and intensity of infection due to paragonimus uterobilateralis in yakurr local government area. | prevalence and intensity of paragonimiasis among inhabitants of the yakurr local government area in the cross river basin of nigeria is reported. diagnosis was based on a single sample detection of eggs of paragonimus in 5 ml of sputum. 12.27% out of 880 subjects were infected. the infections were due to paragonimus uterobilateralis. prevalence of the infection increased with age, up to a peak prevalence of 23.75% (19 out of 108) among subjects between the ages of 17-22 y old. thereafter, it dec ... | 1998 | 9581454 |
| identification of african paragonimidae by multivariate analysis of the eggs. | a study of metacercariae and adult paragonimidae revealed the existence in west-africa of four species, of which two are largely recorded in literature (paragonimus africanus and paragonimus uterobilateralis), one was suspected (paragonimnus westermani-like) and one remained unrecorded in africa (euparagonimus sp). among the two last ones, p. westermani-like was probably confused with p. africanus, and euparagonimus sp. with p. uterobilateralis. p. westermani-like adult worms differed from p. af ... | 1999 | 9924963 |
| otitis media and a neck lump--current diagnostic challenges for paragonimus-like trematode infections. | a 29 year-old nigerian studying in the uk presented with a neck lump and otitis media. paragonimus-like trematode eggs were found in the neck lump aspirate. morphologically these eggs resembled paragonimus uterobilateralis or achillurbainia congolensis. we favoured the diagnosis of achillurbainiasis over extrapulmonary paragonimiasis on the basis of clinical features and because we could not amplify dna sequences using pcr primers specific for paragonimus species. we discuss current diagnostic c ... | 2007 | 16824610 |
| prevalence and intensity of paragonimus uterobilateralis infection among school children in oban village, south eastern, nigeria. | a survey of paragonimus infection among primary school children aged 6-10 years in oban village, akamkpa local government area of cross river state, nigeria, was conducted. a total of 198 children were examined:112 (56.6%) were boys while 86 (43.4%) were girls. eleven of the subjects were sputum positive for paragonimus eggs, giving an overall prevalence rate of 5.5%. the findings show that paragonimiasis is a significant health problem in south eastern nigeria; the risk of infection could be mi ... | 2007 | 17988485 |