| in vitro comparison of cilofungin alone and in combination with other antifungal agents against clinical isolates of candida species. | cilofungin, a lipopeptide antifungal agent, was tested for in vitro activity alone and in combination with ketoconazole, itraconazole, flucytosine and amphotericin b against 102 clinical isolates of candida species. at 48 hours all isolates of candida albicans, candida tropicalis, candida paratropicalis and candida glabrata were inhibited by less than or equal to 5 meg/ml of cilofungin. in contrast, the mic90 for candida krusei was 10 mcg/ml and for candida parapsilosis greater than 40 mcg/ml. t ... | 1991 | 1655435 |
| characterization of the mycoflora from oral mucosal surfaces of some hiv-infected patients. | oral mucosal surfaces from 54 patients seropositive for human immunodeficiency virus (hiv) were assayed for the presence of cultivable yeasts. oral colonization with candida albicans, represented by 6 biotypes, was evident in 35 persons. the closely related variant, candida stellatoidea, was found in 3 patients. single isolates of candida parapsilosis, candida glabrata, candida tropicalis, and candida paratropicalis were also identified. one patient harbored a population of saccharomyces cerevis ... | 1990 | 2192330 |
| protein and enzyme electrophoresis profiles of selected candida species. | the cellular protein profiles and malate dehydrogenases, superoxide dismutases, alkaline phosphatases, and esterases from whole cell extracts of candida spp. were studied with polyacrylamide gel electrophoresis. we investigated isolates that differed in their ability to assimilate sucrose as the sole carbon source. the protein and enzyme patterns of candida tropicalis and its sucrose-negative variant "candida paratropicalis baker, salkin, pincus et d'amato" were indistinguishable. although the c ... | 1989 | 2654176 |
| uncommon yeastlike zoopathogens and commercial systems for their identification. | opportunistic infections caused by yeasts or yeastlike fungi have increased in incidence in recent years as a result of clinical and therapeutic factors. several formerly uncommon yeastlike zoopathogens--candida lusitaniae, candida paratropicalis (sucrose-negative variant of candida tropicalis), trichosporon beigelii, blastoschizomyces capitatus, and rhodotorula species--have been isolated from patients with invasive infections. the increased isolation of such opportunistic pathogens from a vari ... | 1987 | 3309664 |
| pathogenicity of candida paratropicalis. | a new candida species, candida paratropicalis, was recently described. four cases of infections due to c paratropicalis are reviewed in detail and an additional five cases are reviewed to establish the clinical relevance of this species of yeast. candida paratropicalis was isolated from blood and several other body sites. although the isolates tested were sensitive in vitro to amphotericin b and fluocytosine, significant morbidity and mortality were associated with the infections. | 1983 | 6578708 |
| random amplified polymorphic dna for strain delineation within candida tropicalis. | candida tropicalis dna was used as a template in a polymerase chain reaction (pcr) utilizing a 10-mer primer to generate random amplified polymorphic dna (rapd). rapd patterns associated with 25 primers were obtained for six epidemiologically-unrelated isolates, then a subset of six primers were selected to screen a panel of 18 isolates of c. tropicalis and six isolates of candida paratropicalis, a species that resembles c. tropicalis but has a sucrose-negative phenotype. the panel, which includ ... | 1995 | 8531022 |