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babesia argentina: observations on the immunogenicity of the cryofibrinogen complex.rabbit antisera were prepared against the soluble and insoluble fractions of a cryofibrinogen complex that formed in plasma of cattle acutely infected with babesia argentina. analyses of the rabbit antisera indicated that the cryofibrinogen complex contained proteins from erythrocytes and parasites as well as fibrinogen and related proteins.1977335689
an electron microscopic study of intra-erythrocytic stages of babesia bovis in the brain capillaries of infected splenectomized calves.splenectomized vaccine donor calves undergoing primary reactions to babesia bovis infections may develop cerebral babesiosis which leads to death if not treated in time. a brain biopsy was performed on an artificially-infected animal showing nervous symptoms and the tissue was immediately processed for electron microscopic examination. virtually every erythrocyte in the brain capillaries sectioned was infected with b. bovis. intra-erythrocytic merozoites, trophozoites and dividing trophozoites w ...1979460822
efficacy of attenuated anaplasma marginale vaccine under laboratory and field conditions in colombia.four-month-old holstein-friesian calves were inoculated with 3 different doses (1, 2, and 3 ml) of attenuated anaplasma marginale vaccine. vaccinated calves showed mild anaplasma parasitemia, slight decrease in packed cell volume, low serologic conversion, and no clinical illness. an artificial challenge exposure of vaccinated and unvaccinated calves with virulent colombian a marginale showed that the vaccine provided protection against clinical signs of the disease, including parasitemia and an ...1978629456
the duration of latent infection and functional immunity in droughtmaster and hereford cattle following natural infection with babesia argentina and babesia bigemina.tne droughtmaster and 9 hereford cattle were born in an enzootic babesiasis area and became naturally infected with babesia argentina and b.bigemina during a 3 year period. they were then kept free of cattle ticks (boophilus microplus) for the remainder of the experiment. annually for the next 3 years their individual infection status with babesia was determined by sub-inoculation of blood into splenectomised calves. at the end of this period the functional immunity of all cattle was challenged ...1978655965
methods to improve the health of cattle in the tropics: immunisation and chemoprophylaxis against haemoparasitic infections.a study of methods to improve the health of native cattle in tropical areas of colombia showed an advantage using immunisation techniques against haemoparasitic infections in comparison with other control methods. the control of anaplasmosis and babesiosis by immunisation of cattle with fully virulent anaplasma marginale, babesia argentina and b. bigemina is feasible in tropical cattle when the postimmunisation reaction is controlled by appropriate drug therapy. chemoprophylaxis was found less e ...1978664017
immunization against anaplasmosis and babesiosis. part ii. evaluation of cryo-preserved vaccines using different doses and routes of inoculation.anaplasma marginale, babesia argentina and babesia bigemina infected blood used as vaccines for immunization trials in valle del cauca, were preserved with 4 molar dimethyl-sulfoxide (4m dmso) and stored in liquid nitrogen (-196 degrees c). the effectivity of the vaccines was determined in 87 healthy calves utilizing serial 10-fold dilutions. the effects of dose, inoculation routes, time and temperature were determined. the minimum infective dose for a. marginale was 10(-3) (2 x 10(6)) when 2 ml ...1978675843
methods to improve the health of cattle in the tropics: conclusions and economic appraisal.the results of the immune responses of immunised and chemoprophylactically treated calves to tick-borne (boophilus microplus) challenge indicate that the system of immunisation was effective in protecting cattle against anaplasma marginale, babesia argentina (bovis), and b. bigemina. however, chemoprophylaxis was effective only against babesia spp. but not against a. marginale. both methods showed a substantial advantage over no control system when using native cattle breeds in a zone endemic fo ...1978705891
evaluation of the indirect fluorescent antibody test for detecting trypanosoma vivax in south american cattle.the indirect fluorescent antibody test (ifat) as used in africa for detecting bovine trypanosomiasis was adapted for use in south america and evaluated. antigen consisted of trypanosoma vivax laden bovine blood fixed in a 60 : 40 : : acetone : methanol solution. the test detected initial titres of 1 : 50 and 1 : 100 at an average of 13.1 and 15.9 days post parasitaemia (pp). maximum titres as high as 1 : 400 developed in eight calves at an average of 23.4 days pp. in another calf, 109 days pp we ...1976781765
comparison of indirect fluorescent antibody (ifa) with complement fixation (cf) tests for diagnosis of babesia spp infections in colombian cattle.a total of 372 serum samples were collected from colombian cattle before and during the course of natural babesia spp. infection on the north coast of colombia. the serum samples were used to compare indirect fluorescent antibody (ifa) with complement fixation (cf) tests for diagnosis of babesiosis. the ifa technique detected babesia argentina antibodies an average of 4.0 weeks earlier than the cf test and babesia bigemina an average of 2.5 weeks earlier. both ifa and cf were capable of differen ...1976781955
tolerance to imidocarb induced experimentally in tick-transmitted babesia argentina.babesia argentina was repeatedly exposed to imidocarb by transmitting parasites from infected ticks in a series of 4 groups of nonsplenectomised calves that had been treated prophylactically at 2 mg/kg. as the number of exposures to imidocarb increased, the parasites more readily infected the treated calves, indicating increased tolerance to the drug. tests comparing parasites not previously exposed to imidocarb with those exposed 4 times showed that a dose of 3 mg/kg imidocarb completely cured ...1977869813
bovine haemoglobin types and their possible relationship to resistance to babesiosis: an experimental study.two groups of droughtmaster cattle, one group previously infected, were challenged with babesia argentina infected erythrocytes. all animals were typed for haemoglobin and the course of infection followed by regular parasite counts. no conclusive relationship between the frequencies of the hba and hbb genes and the severity of parasitaemia in the different groups was found. the presence of hbf was not associated with any limitations on the severity of infection in 1 1/2 - 2 1/2 months calves.1977910284
babesia argentina: studies on the nature of an antigen associated with infection. 1976945246
babesia argentina: disseminated intravascular coagulation in acute infections in splenectomized calves. 1976949999
serological comparison of australian and south american strains of babesia argentina and anaplasma marginale. 1976955774
erythrocyte adenosine triphosphate levels in cattle infected with babesia argentina.erythrocyte adenosie triphosphate (atp) was estimated in 60 droughtmaster cattle. the mean was 0.76 mumole/g haemoglobin; standard deviation +/- 0.18; range 0.41-1.45. atp values were log normally distributed. repeatability of atp estimations was confirmed using 10 hereford cattle. animal variation in the estimates was double the sampling variation. no significant correlation between susceptibility to b. argentina and atp was observed in 25 droughtmaster and 5 hereford cattle.1976982554
immunization against anaplasmosis and babesiosis: part i. evaluation of immunization using minimum infective doses under laboratory conditions.a method of immunization against anaplasmosis and babesiosis using minimum infective doses was developed under laboratory conditions. stabilates of anaplasma marginale stored at -60 degrees c were found infective when diluted 10-fold to 10(-3). stabilates of babesia argentina and babesia bigemina stored under the same conditions were infective when diluted 10-fold to 10(-1). intact calves inoculated with the above dilutions of stabilates developed moderate parasitemias and recovered from infecti ...19761006801
infection rates and outbreaks of disease due to babesia argentina in unvaccinated cattle on 5 beef properties in south-eastern queensland.serums from unvaccinated groups in 5 herds of beef-cattle in south-east queensland were tested for antibodies to babesia argentina at intervals while the cattle were increasing in age from about 6 months. an indirect fluorescent antibody test was used. infection rates, indicating the proportions of the groups that had been exposed to tick-transmitted infection were 49.2, 56.9 and 69.1% for cattle aged approximately 6, 12 and 18 months, respectively. the degree to which cattle were infested with ...19761016134
vaccination with babesia argentina in 5 beef herds in south-eastern queensland.observations on the use of a vaccine containing babesia argentina in 5 partly susceptible beef herds in south-eastern queensland were made on 1,029 female breeding cattle over a period of 4 years. groups averaging about 20 heifers were given 0, 1, 2 or 3 vaccinations. incidence derived from groups experiencing clinical attacks were 17.9% for unvaccinated cattle and 1.2% for vaccinates. increasing the number of vaccinations did not appear to increase protection. the one clinical manifestation of ...19761016135
effect of trasylol on packed cell volume and plasma kallikrein activation in acute babesia argentina infection of splenectomised calves.three groups of four splenectomised calves, three months old, were infected with babesia argentina parasites. one group was inoculated intravenously with 2000 kallikrein inhibitor units (kiu)/kg body weight of the broad-spectrum proteinase inhibitor, trasylol, three times a day for 5 days commencing on the 3rd day after infection (early treatment). the same dose of trasylol was given to a second group for 3 days commencing 8 days after infection (late treatment). the third group was untreated. p ...19751079995
babesia bigemina, babesia argentina, and anaplasma marginale: coinfectious immunity in bovines. 19751123013
a cold precipitable fibrinogen complex in the plasma of cattle dying from infection with babesia argentina.plasma from cattle dying from infection with babesia argentina formed a cold precipitable gel when stored at 4 degrees c. immunodiffusion and electrophoresis showed the soluble phase of the gel to consist mainly of a fibrinogen-like protein with small amounts of other plasma proteins. gel filtration and specific clotting assays demonstrated a wide molecular weight spectrum of fibrinogen-like proteins, most of which appeared to be soluble fibrin in either monomer or complex forms. the possibility ...19751220358
piroplasmosis in buffaloes and its serological diagnosis based on a homology between buffalo and bovine immunoglobulins.babesia argentina, babesia bigemina and theileria mutans were transmitted experimentally from water buffaloes (bubalus bubalis) to splenectomised bos taurus calves. buffaloes were positive to an indirect fluorescent antibody test for b. argentina when reagents of bovine origin were used. the formation of similar patterns during immunoelectrophoresis suggested a homology of buffalo and bovine serum proteins, particularly igg.19761267733
studies on antigenic changes and strain differences in babesia argentina infections. 19734124695
plasma kallikrein levels in acute babesia argentina infections in splenectomised and intact calves. 19734126412
proteolytic enzyme activity in the intra-erythrocytic parasites babesia argentina and babesia bigemina. 19734129425
bovine babesiasis: computer simulation of babesia argentina parasite rates in bos taurus cattle. 19744141238
babesia argentina: the infectivity and immunogenicity of irradiated blood parasites for splenectomized calves. 19734196318
observations on the haematology of experimentally induced babesia argentina and b. bigemina infections in splenectomised calves. 19734196561
ultrastructural changes in babesia argentina-infected erythrocytes in kidney capillaries. 19734198651
babesia argentina: intraerythrocytic location of babesial antigen extracted from parasite suspensions. 19734200008
evaluation of an indirect fluorescent antibody test for detecting babesia argentina infection in cattle. 19734201299
a rapid slide agglutination test for the herd diagnosis of babesia argentina infection. 19744411727
evaluation of the passive haemagglutination test for the diagnosis of babesia argentina infection in cattle. 19744413320
diagnosis of babesia argentina infection in cattle using brain smears. 19724568452
the effect of different light sources and filtering systems on the sensitivity of fluorescent tests for babesia argentina antibodies in cattle. 19734591120
a comparison of indirect, direct inhibition and labelled anticomplement fluorescent antibody tests in the detection of babesia argentina infection in cattle. 19734591121
the immunity of cattle to babesia argentina after drug sterilisation of infections of varying duration. 19744594671
a direct counting technique for estimating high parasitaemias in infections of babesia argentina, babesia bigemina and plasmodium berghei. 19734595621
babesia argentina: immunogenicity of plasma from infected animals. 19724626125
babesia argentina, plasmodium vivax and p. falciparum: antigenic cross-reactions. 19724630690
an electron microscopic study of intravascular agglutination in the cerebral cortex due to babesia argentina infection. 19724652608
bovine babesiasis: the persistence of immunity to babesia argentina and b. bigemina in calves (bos taurus) after naturally acquired infection. 19734722422
chemoprophylaxis (imidocarb) against babesia bigemina and babesia argentina infections. 19734747036
osmotic fragility of erythrocytes in acute babesia argentina and babesia bigemina infections in splenectomised bos taurus calves. 19734792009
blood group antibody production in cattle by a vaccine against babesia argentina. 19734792010
bovine babesiosis: sterile immunity to babesia bigemina and babesia argentina infections. 19734807692
measurement of and correlations between fever, changes in the packed cell volume and parasitaemia in the evaluation of the susceptibility of cattle to infection with babesia argentina. 19744819467
babesia argentina: the infection of splenectomized calves with extracts of larval ticks (boophilus microplus). 19744819982
the activation of kallikrein in acute babesia argentina infections of splenectomised calves. 19744854636
bovine babesiosis: the passive immunization of calves against babesia argentina with special reference to the role of complement fixing antibodies. 19674961047
bovine babesiosis: the immunization of cattle with killed babesia argentina. 19674961048
loss of infectivity of a vaccine strain of babesia argentina for boophilus microplus. 19664961183
babesia argentina: serum changes in infected calves. 19694978878
diagnosis of babesia argentina infections in cattle using brain smears. 19725013810
studies on the pathogenesis of babesia argentina and babesia bigemina infections in splenectomised calves. 19725081456
the acquired resistance to babesia argentina of cattle exposed to light infestation with cattle tick (boophilus microplus). 19715106905
observations on the pathology of babesia argentina infections in cattle. 19715106906
differential diagnosis of babesia argentina and babesia bigemina infections in cattle using thin blood smears and brain smears. 19715106907
the prophylactic effects of imidocarb against babesia argentina and babesia bigenima infections of cattle. 19715166579
chemoprophylaxis in babesia argentina infection in cattle. 19695353494
vaccination against babesia argentina infection in cattle during chemoprophylaxis with a quinuronium compound. 19695389523
bovine babesiosis: duration of latent infection and immunity to babesia argentina. 19695408640
the effect of imidocarb against babesia argentina and babesia bigemina infections of cattle. 19705464834
the prevalence of babesia bovis (babesia argentina) in the brains of slaughter cattle in northern nigeria. 19675629275
in vitro agglutination of bovine erythrocytes infected with babesia argentina. 19685639134
field observations on babesia argentina vaccination in queensland. 19685689432
a note on homologous strain immunity in babesia argentina infections. 19685690590
cortisone-induced relapses in babesia argentina infections of cattle. 19695814040
a new vaccine for babesia argentina infection prepared in splenectomised calves. 19665962488
an indirect haemagglutination test for the diagnosis of babesia argentina infection in cattle. 19676069193
vaccination against bovine babesiosis. infectivity and virulence of blood from animals either recovered from or reacting to babesia argentina. 19676069699
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