Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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| role of small mammals in the persistence of louping-ill virus: field survey and tick co-feeding studies. | louping-ill (li) is a tick-borne viral disease of red grouse, lagopus lagopus scoticus lath. (tetraonidae: galliformes), and sheep, ovis aries l. (bovidae: artiodactyla), that causes economic loss to upland farms and sporting estates. unvaccinated sheep, grouse and mountain hares, lepus timidus l. (leporidae: lagomorpha), are known to transmit li virus, whereas red deer, cenrus elaphus l. (cervidae: artiodactyla), and rabbits, oryctolagus cuniculus l. (leporidae: lagomorpha), do not. however, th ... | 2000 | 11016435 |
| dna vaccination of mice with a plasmid encoding puumala hantavirus nucleocapsid protein mimics the b-cell response induced by virus infection. | inoculation of naked dna has been applied for the development of prophylactic and therapeutic vaccines against different viral infections. to study the humoral immune response induced by dna vaccination we cloned the entire nucleocapsid protein-encoding sequence of the puumala hantavirus strain vranica/hällnäs into the cmv promoter-driven expression unit of the plasmid pcdna3, generating pcdna3-vr1. a single dose injection of 50 microg of plasmid dna into each m. tibialis anterior of balb/c mice ... | 2001 | 11035190 |
| murine gammaherpesvirus-68 infection of and persistence in the central nervous system. | murine gammaherpesvirus-68 (mhv-68) was originally isolated from a bank vole by passage through mouse brain. given its ability to replicate in mouse brain and its subsequent reisolation from trigeminal ganglia, it was originally considered to be an alphaherpesvirus. molecular studies have now firmly established mhv-68 to be a gammaherpesvirus. other gammaherpesviruses have been suggested to cause and in some cases shown to cause neurological disease. given the isolation history of mhv-68, we hav ... | 2000 | 11038374 |
| puumala (puu) hantavirus strain differences and insertion positions in the hepatitis b virus core antigen influence b-cell immunogenicity and protective potential of core-derived particles. | hepatitis b virus (hbv) core-derived chimeric particles carrying a puumala (puu) hantavirus (strain vranica/hällnäs) nucleocapsid (n) protein sequence (aa 1-45), alternatively inserted at three distinct positions (n-, c-terminus, or the internal region), and mosaic particles consisting of hbv core as well as core/puu (vranica/hällnäs) n (aa 1-45) readthrough protein were generated. chimeric particles carrying the insert at the n-terminus or the internal region of core induced some protective imm ... | 2000 | 11040127 |
| dietary cadmium induces histopathological changes despite a sufficient metallothionein level in the liver and kidneys of the bank vole (clethrionomys glareolus). | the objective of this study was to correlate hepatic and renal cadmium (cd) accumulation, cd-binding capacity of metallothionein (mt) and lipid peroxidation with the tissue injury in the male bank voles raised under short (8 h light/16 h dark) and long (16 h light/8 h dark) photoperiods that affect differently cd accumulation and mt induction in these rodents. the animals were exposed to dietary cd (0, 40 and 80 microg/g) for 6 weeks. the accumulation of cd in the liver and kidneys appeared to b ... | 2000 | 11048661 |
| babesia divergens in france: descriptive and analytical epidemiology. | babesia divergens cause of bovine babesiosis transmitted by ixodes ricinus, is widely spread especially in west, central and south-west parts of france. it occurs with two annual peaks, in spring and autumn. the study was carried out during a period of two years (1991-1993) in four farms in the sarthe area, in order to know the distribution and the ecology of i. ricinus, and to show the presence of b. divergens. cattle are parasitised as early as march essentially by adult ticks, according to a ... | 1999 | 11071546 |
| molecular evolution of puumala hantavirus in fennoscandia: phylogenetic analysis of strains from two recolonization routes, karelia and denmark. | like other members of the genus hantavirus: in the family bunyaviridae:, puumala virus (puuv) is thought to be co-evolving with its natural host, the bank vole clethrionomys glareolus. to gain insight into the evolutionary history of puuv in northern europe during the last post-glacial period, we have studied wild-type puuv strains originating from areas along two postulated immigration routes of bank voles to fennoscandia. full-length sequences of the s rna segment and partial sequences (nt 216 ... | 2000 | 11086113 |
| nmr spectroscopy based metabonomic studies on the comparative biochemistry of the kidney and urine of the bank vole (clethrionomys glareolus), wood mouse (apodemus sylvaticus), white toothed shrew (crocidura suaveolens) and the laboratory rat. | the metabolic profiles of three wild mammals that vary in their trophic strategies, the herbivorous bank vole (clethrionomys glareolus), the granivorous wood mouse (apodemus sylvaticus), and the insectivorous white-toothed shrew (crocidura suaveolens), were compared with that of a widely used strain of laboratory rat (sprague dawley). in conjunction with nmr spectroscopic investigations into the urine and blood plasma composition for these mammals, high resolution magic angle spinning (hrmas) 1h ... | 2000 | 11126766 |
| prevalence of igg antibodies response to borrelia burgdorferi s.l. in populations of wild rodents from mazury lakes district region of poland. | three rodent species: clethrionomys glareolus, apodemus flavicollis and microtus arvalis from mazury lakes district of poland were examined for antibodies to borrelia burgdorferi by enzyme-labelled protein g assay (elga). c. glareolus had an exceptionally high prevalence of b. burgdorferi antibodies - 58%, but a. flavicollis and m. arvalis also showed significant prevalence of 16.6% and 10.5%, respectively. the elga method is highly specific with good reproducibility. nevertheless, some differen ... | 2000 | 11153035 |
| s-100 protein immunoreactivity in mammalian testis and epididymis. | the present study deals with immunohistochemical localization of s-100 protein in mouse, bank vole and pine vole testis and epididymis. s-100 protein immunoreactivity was observed in the endothelia of capillaries and lymphatic sinusoids of pine vole testis. a reaction to s-100 protein of the same intensity as that noted in the endothelia of testicular capillaries was found in myoid cells of pine vole and bank vole seminiferous tubules. moreover, a positive reaction to s-100 protein was observed ... | 2000 | 11185720 |
| factors affecting the component community structure of haemoparasites in bank voles (clethrionomys glareolus) from the mazury lake district region of poland. | the prevalence and abundance of infections with haemoparasites were studied over a 3 year period in clethrionomys glareolus (bank vole, n = 420) sampled from forests in the ne of poland. total species richness was 5 (prevalence = haemobartonella sp. 63.1%, bartonella grahamii 27.4%, hepatozoon erhardovae 31.4%, trypanosoma evotomys 15% and babesia microti 1.0%) with 81.9% of the voles carrying at least 1 species and a mean infracommunity species richness of 1.4. variation in species richness was ... | 2001 | 11197763 |
| [ecological and epizootic characteristics of various zonal types of natural reservoirs of alveococcosis in the omsk region]. | natural foci of alveococcis of various zonal types were found in the omsk region. the final pathogen hosts are red (aspen and birch forests, northern and southern forest-steppe, steppe) and corsac (southern forest-steppe and steppe) foxes and, perhaps, wolves (southern taiga). there are intermediate hosts, that are small mammals of 10 species, among which clethrionomys voles (northern redbacked, large-toothed redbacked, and bank voles in the southern taiga; northern redbacked voles in the aspen ... | 2000 | 11210415 |
| genetic characterization of puumala hantavirus strains from belgium: evidence for a distinct phylogenetic lineage. | puumala hantavirus (puuv) sequences were recovered from red bank voles (clethrionomys glareolus) trapped between 1996 and 1998 in four localities of southern belgium: thuin, montbliart, momignies and couvin. in addition, three puuv isolates originating from bank voles trapped in the 1980s in southern (montbliart) and northern (turnhout) belgium were genetically characterized. analysis of the complete s and partial m segment sequences showed that the belgian puuv strains constitute a genetic line ... | 2001 | 11226569 |
| testosterone depresses innate and acquired resistance to ticks in natural rodent hosts: a force for aggregated distributions of parasites. | the effects of testosterone on acquired resistance to ticks, ixodes ricinus, in their natural rodent hosts (voles, clethrionomys glareolus, and wood-mice, apodemus sylvaticus) were investigated by manipulating testosterone levels and exposing the hosts to repeated tick infestations. testosterone reduced both innate and acquired resistance to tick feeding. during primary infestations, attachment rates were higher on rodents with high testosterone levels than on oil-implanted controls. successive ... | 2001 | 11227902 |
| [mutagenesis in muridae from regions with increased radiation level]. | genetic monitoring of wild populations of mouse-like rodents has been carried out since 1992 in areas with the increased radioactivity in the south of the bryansk region. the radioactive background ranged from 0.20 to 2.20 mkgy/h. over 400 rodents of different species have been examined. bank vole constituted more than a half of the examined animals. the genetic effect of radiation was estimated by the frequency of micronuclei in normochromatic erythrocytes of peripheral blood and by the frequen ... | 2000 | 11252236 |
| optimal allocation of reproductive effort: manipulation of offspring number and size in the bank vole. | the number of offspring attaining reproductive age is an important measure of an individual's fitness. however, reproductive success is generally constrained by a trade-off between offspring number and quality. we conducted a factorial experiment in order to study the effects of an artificial enlargement of offspring number and size on the reproductive success of female bank voles (clethrionomys glareolus). we also studied the effects of the manipulations on growth, survival and reproductive suc ... | 2001 | 11297185 |
| serological evidence that mus musculus is the natural host of theiler's murine encephalomyelitis virus. | theiler's murine encephalomyelitis virus (tmev) infection is maintained in mouse colonies by fecal-oral spread (with no apparent role for persistent central nervous system infection) from an acutely infected animal to another. therefore, serological methods offer the principal way to assess infection in mice and related rodent populations. infection of mouse colonies with tmev appears to be worldwide, yet no systematic serologic studies have been reported. in this study, enzyme-linked immunoassa ... | 2001 | 11376848 |
| germ cells: a new source of estrogens in the male gonad. | the cytochrome p450 aromatase (p450arom) is a key enzyme responsible for the formation of estrogens from androgens and is present in the endoplasmic reticulum of various tissues. p450arom has been immunolocalized in leydig cells of numerous species as well as in germ cells of mouse, bank vole and brown bear. aromatase activity has been measured in vitro in immature and mature rat leydig cells and sertoli cells, whereas in pig, ram and humans the enzyme activity is only present in leydig cells. i ... | 2001 | 11403896 |
| photoperiod-dependent capability of androgen aromatization and the role of estrogens in the bank vole testis visualized by means of immunohistochemistry. | detection of steroid hormone receptors within a target tissue is important for an understanding of their crucial role in regulating of steroids' action. in the light of recent knowledge on the role of estrogens in male gonads the efforts were undertaken to clarify and discuss a role of androgen receptors, aromatase and estrogen receptors (er) in mediating testosterone and/or estradiol action in testicular cells of bank voles that were kept under short or long light cycles. immunohistochemistry w ... | 2001 | 11403909 |
| [viral infectious and chromosome aberrations in bank vole from natural and laboratory populations]. | the frequency of chromosome damage was studied in the carriers of virus of the hemorrhagic fever with renal syndrome (puumala virus) and in noninfected animals from two laboratory colonies and two natural populations of bank vole. in the laboratory colony, where puumala virus persisted for three years, multiaberrant ("rogue") cells were found in the bone marrow; the mean frequencies of both structural and numeral chromosome abnormalities were significantly enhanced. in the other laboratory colon ... | 2001 | 11421123 |
| modifying the cellular transport of dna-based vaccines alters the immune response to hantavirus nucleocapsid protein. | puumala virus is a member of the hantavirus genus (family bunyaviridae) and is one of the causative agents of hemorrhagic fever with renal syndrome (hfrs) in europe. a genetic vaccination approach was conducted to investigate if the immune response could be modulated using different cellular secretion and/or localisation signals, and the immune responses were analysed in balb/c mice and in a bank vole infectious model. rodents vaccinated with dna constructs encoding the antigen fused to an amino ... | 2001 | 11427253 |
| the involvement of dopamine (da) and serotonin (5-ht) in stress-induced stereotypies in bank voles (clethrionomys glareolus). | in order to clarify the dependency of stress-induced stereotypies on dopamine (da) and serotonin (5-ht) functioning, undisturbed and acutely stressed stereotyping bank voles were treated during 3 weeks with the commonly used human atypical neurolepticum clozapine and the ssri antidepressant citalopram. clozapine blocks da receptors (d sub (4)) and acts as a partial 5-ht antagonist (5-ht sub (2) receptors), while citalopram increases 5-ht transmitter activity. levels of stereotypies were quantifi ... | 2001 | 11434965 |
| importance of surveillance of tularemia natural foci in the known endemic area of central europe, 1991-1997. | marked activation of natural foci of tularemia in the known endemic area of central europe, comprising the borderland of slovakia, austria and the czech republic, led to an epidemic outbreak in western slovakia and an increase in the number of human tularemia cases in the adjoining regions of northeastern austria and southern moravia from 1995 to 1997. the aim of this paper was to present the results of a longitudinal study on the prevalence of infection with francisella tularensis in small mamm ... | 2001 | 11467089 |
| consequences of polluted environments on population structure: the bank vole (clethrionomys glareolus) at chornobyl. | the accident at the chornobyl nuclear power plant in april 1986, released 100-200 million curies of radioactive material into the surrounding environment. to investigate the possible genetic and population effects resulting from chronic exposure to this environmental radiation, we have examined mitochondrial dna (control region) sequences from bank voles, clethrionomys glareolus, inhabiting contaminated sites. our analysis indicates genetic diversity is elevated in the contaminated sites when co ... | 2001 | 11501430 |
| high-resolution magic angle spinning 1h-nmr spectroscopy studies on the renal biochemistry in the bank vole (clethrionomys glareolus) and the effects of arsenic (as3+) toxicity. | 1. high-resolution magic angle spinning (mas) 1h-nmr spectroscopy was used to study renal metabolism and the toxicity of as3+, a common environmental contaminant, in the bank vole (clethrionomys glareolus), a wild species of rodent. 2. following a 14-day exposure to an environmentally relevant dose of as2o3 (28 mg kg(-1) feed), voles displayed tissue damage at autopsy. mas 1h spectra indicated abnormal lipid profiles in these samples. 3. tissue necrosis was also evident from measurements of the ... | 2001 | 11513249 |
| accumulation of 137cesium and 90strontium from abiotic and biotic sources in rodents at chornobyl, ukraine. | bank voles (clethrionomys glareolus) and laboratory strains of house mice (mus musculus balb and c57bl) were relocated into enclosures in a highly contaminated area of the red forest near the chornobyl (ukraine) reactor 4 to evaluate the uptake rates of 137cs and 90sr from abiotic sources. mice were provided with uncontaminated food supplies, ensuring that uptake of radionuclides was through soil ingestion, inhalation, or water. mice were sampled before introduction and were reanalyzed every 10 ... | 2001 | 11521818 |
| experimental exposure of naive bank voles (clethrionomys glareolus) to the chornobyl, ukraine, environment: a test of radioresistance. | previous studies have demonstrated no difference in micronucleus (mn) frequencies between wild rodents chronically exposed to the environmental radiation contamination of the chornobyl (ukraine) exclusion zone and those inhabiting reference populations. the aim of the present study was to test the hypothesis that a population of bank voles (clethrionomys glareolus) has developed radioresistance as a result of 14 years of chronic, low-dose radiation exposure. naive voles were placed in environmen ... | 2001 | 11521819 |
| biomonitoring of contaminated mine tailings through age accumulation of trace metals in the bank vole (clethrionomys glareolus). | lead, zinc and cadmium were determined in a range of tissues from laboratory-bred bank voles (clethrionomys glareolus) exposed to elevated levels of dietary zinc (124 micrograms g-1). the pelletised diet was derived from vegetation harvested from the surface of a revegetated tailings dam at a modern zn-pb mine. exposure regimes to the contaminated diet were 16, 32, 64, 128 or 256 days. elevated levels of dietary zinc were not reflected in the individual tissue or total body concentrations. margi ... | 1999 | 11529106 |
| effect of high-fat diet on body mass and energy balance in the bank vole. | we tested the hypothesis that animals that reduce their body mass in response to decreased photoperiod do not develop diet-induced obesity (dio) when fed a high-fat diet (hfd). bank voles (clethrionomys glareolus) fed a diet with fat content of 13.5% by mass and 28.2% by energy, for 5 weeks, did not develop hyperphagia and were resistant to dio, consistent with predictions. there was no significant difference between food (g/day) or energy intake (kj/day) between the experimental or control grou ... | 2006 | 11564453 |
| [species specificity of karyotype instability under conditions of radionuclide contamination (the chernobyl nuclear power plant) in the voles, micrototus oeconomus, micrototus arvalis, and clethrionomys glareolus]. | the comparative analysis of frequencies of different type cytogenetic anomalies in voles microtus oeconomus, microtus arvalis, clethrionomys glareolus trapped in territories with different levels of radionuclide contamination inside the 30-km zone of estrangement around the chernobyl npp was carried out. animals with constitutive chromosome abnormalities were not revealed. the frequency of lympocytes with micronuclei was the most universal and sensitive character to chronic low-dose radiation in ... | 2001 | 11589050 |
| variation in the helminth community structure in bank voles (clethrionomys glareolus) from three comparable localities in the mazury lake district region of poland. | we tested the null hypothesis that populations of hosts trapped in isolated neighbouring locations showing comparable habitat quality, should support similar helminth parasite communities. the study was undertaken in a 2-week period in late summer in ne poland in a single year, thereby eliminating seasonal and between-year variation in parasite burdens. a total of 139 clethrionomys glareolus (bank vole) were sampled from 3 forest sites of similar habitat quality. total species richness was 11 (6 ... | 2001 | 11676372 |
| [hantavirus infection in bank voles in the natural reservoir. part 1. characteristics of an infection process in bank voles]. | the specific features of hantavirus infection in naturally infected bank voles (clethrionomys glareolus), the principal host of hantavirus of the serotype puumala, were studied during long-term observation of individually marked animals in the active focus of hemorrhagic fever with renal syndrome (hfrs) in the south of udmurtia. the infection time in the bank voles was defined by paired serum seroconversion tests. in the natural focus, hantavirus was shown to cause asymptomatic persistent infect ... | 2001 | 11680366 |
| [organization of treatment and diagnosis of hemorrhagic fever with renal syndrome in udmurtiia]. | the paper presents basic parameters that characterize the status of prevention, treatment, diagnosis, and rehabilitation in hemorrhagic fever with renal syndrome (hfrs). the data from the epidemiological surveillance in the republic indicate the poor epidemic situation: with decreased immunization there are rises in morbidity and viral infection from the main source bank voles. the paper suggests possible ways of improving preventive measures. the mechanism of improvement of health care to patie ... | 2009 | 11680380 |
| antigenic profile of ixodes ricinus: effect of developmental stage, feeding time and the response of different host species. | antigens recognized by host species in response to ectoparasite infestation have been widely reported. although differences in the immune responses of different host species have been described, only a very few of these studies compare the range of antigens recognized by different host species in response to infestation. we used western blot analysis to investigate antigenic responses of different host species that were repeatedly infested with ixodes ricinus ticks. antigenic profiles of larval ... | 2001 | 11696166 |
| [hantavirus infection epidemiology in belgium]. | in europe, puumala (puu) is a hantavirus responsible for a human disease called nephropathia epidemica and its natural reservoir is the red bank vole, (clethrionomys glareolus). although the population densities and the prevalence rates of infection were high in red bank voles in southern belgium during the 1996 and 1999 epidemic years, the percentages of infected rodents were low in 1997 and 1998, when only a few positive sites were found. antibodies against puu virus were mainly detected in th ... | 2001 | 11697188 |
| [hemorrhagic fever with renal syndrome]. | puumala hantavirus is the most common hantavirus infection in western europe. the causative agent, puumala virus, is a member of the hantavirus genus in the bunyaviridae family. the natural hosts of hantaviruses are chronically, but asymptomatic infected rodents, which transmit the virus to human in their excretions. puumala virus is carried by the bank vole, clethrionomys glareolus. hemorrhagic fever with renal syndrome (hfrs) caused by puumala virus in france or belgium is very similar to the ... | 2001 | 11715607 |
| first molecular evidence for puumala hantavirus in slovakia. | we report on the first puumala hantavirus nucleotide sequence (strain opina-916) amplified from a bank vole trapped in slovakia, central europe. phylogenetic analysis of the s-segment sequence grouped the virus within the western/central european sublineage of puumala virus. in the neighborhood of the rodent trapping site two cases of human infection by the puumala virus were verified. | 2001 | 11724269 |
| immunolocalization and activity of aromatase in the bank vole testes. | a direct approach to identify the cellular source of p450 aromatase in the bank vole testes (seasonally breeding rodents) is the use of immunohistochemistry with a specific antibody that recognizes this enzyme. to confirm the presence of functional aromatase, its activity was measured in microsomal preparations of whole testes and of seminiferous tubules by means of biochemical assay with tritiated androstenedione. the assay was validated using increasing concentrations of both microsomal prepar ... | 2001 | 11766765 |
| immunolocalization of pthrp in the submandibular glands of three rodent species. | the present study deals with immunohistochemical localization of pthrp in bank vole, pine vole and white mouse submandibular glands. pthrp immunoreactivity was observed in epithelial cells of all ductal segments (intercalated, striated, interlobular and main excretory ducts) of the salivary glands in all the three animal species tested. we also found pthrp expression in myoepithelial cells surrounding the mucous alveoli of submandibular glands in those animals. the reaction was less intense than ... | 2001 | 11766767 |
| haemogregarines of the genus hepatozoon (apicomplexa: adeleina) in rodents from northern europe. | we studied the prevalence and distribution of hepatozoon infections in small rodents from finland and other areas in northern europe. hepatozoon infections were more common in voles (arvicolinae) than mice (murinae) and more prevalent in voles of the genus clethrionomys than in voles of the genus microtus. transmission electron microscopical examination of hepatozoon erhardovae krampitz, 1964 from bank voles clethrionomys glareolus (schreber) showed that intracellular lung meronts were located i ... | 2001 | 11817449 |
| effects of ash application on cadmium concentration in small mammals. | in order to assess the effects of wood ash application to forests on small mammals, we collected bank voles (clethrionomys glareolus) and common shrews (sorex araneus) from a forest area in southern finland. part of the sample population was from sites that had been treated with ash 1.5 years earlier, part from untreated control sites. the ash increased the soil ph and gave an average cadmium load in soil of 44 g ha(-1). when comparing treated and control areas, we found slightly but significant ... | 2013 | 11837422 |
| aromatase expression in male germ cells. | the cytochrome p450 aromatase (p450arom) is the terminal enzyme responsible for the formation of estrogens from androgens. according to the age, aromatase activity has been measured in immature and mature rat leydig cells, as well as in sertoli cells whereas in pig, ram and human the aromatase is mainly present in leydig cells. in the rat testis, we have immunolocalised the p450arom not only in leydig cells but also in germ cells and especially in elongated spermatids. related to the stage of ge ... | 2001 | 11850226 |
| host specificity of trypanosoma (herpetosoma) species: evidence that bank voles (clethrionomys glareolus) carry only one t. (h.) evotomys 18s rrna genotype but wood mice (apodemus sylvaticus) carry at least two polyphyletic parasites. | the strongest evidence for host specificity of mammalian trypanosomes comes from parasites of the subgenus trypanosoma (herpetosoma). laboratory studies have shown that t. (herpetosoma) species will not infect an alternative host. however, this has not been demonstrated in wild populations. we screened 560 bank voles (clethrionomys glareolus) and 148 wood mice (apodemus sylvaticus) for trypanosomes by pcr amplification of the 18s rrna gene. in total, 109 (19%) bank voles and 12 (8%) wood mice we ... | 2002 | 11860034 |
| phylogenetic analysis of ljungan virus and a-2 plaque virus, new members of the picornaviridae. | in addition to the viruses belonging to the nine proposed genera of the picornaviridae, enterovirus, rhinovirus, cardiovirus, aphtovirus, hepatovirus, parechovirus, kobuvirus, erbovirus and teschovirus, two new members of this family have recently been discovered. three strains of ljungan virus (lv) were isolated from bank voles (clethrionomys glareolus) and a-2 plaque virus (a-2) was isolated from human sera. to study the genetic relationship between these recently discovered viruses and the me ... | 2002 | 11955639 |
| tula hantavirus in belgium. | european common voles (microtus arvalis), captured in belgium in 1999, were proven by molecular as well as by serological techniques to be infected with tula hantavirus (tulv). this is the first evidence for the presence of tulv in this country. no indication of spill-over infections of puumala virus, known to be highly endemic among bank voles (clethrionomys glareolus) within the same geographical regions as the trapped tulv-infected common voles, was observed. together with previous reports on ... | 2002 | 12002543 |
| intraspecies interactions in the bank vole: field observation data. | 2017 | 12004887 | |
| local variation in endoparasite intensities of bank voles (clethrionomys glareolus) from ecologically similar sites: morphometric and endocrine correlates. | much interest has centred recently on the role of adaptive trade-offs between the immune system and other components of life history in determining resistance and parasite intensities among hosts. steroid hormones, particularly glucocorticoids and sex steroids, provide a plausible mechanism for mediating such trade-offs. a basic assumption behind the hypothesis, however, is that steroid activity will generally correlate with reduced resistance and thus greater parasite intensities. here, we pres ... | 2002 | 12015821 |
| excretion of vancomycin-resistant enterococci by wild mammals. | a survey of fecal samples found enterococcal excretion in 82% of 388 bank voles (clethrionomys glareolus), 92% of 131 woodmice (apodemus sylvaticus), and 75% of 165 badgers (meles meles). vancomycin-resistant enterococci, all enterococcus faecium of vana genotype, were excreted by 4.6% of the woodmice and 1.2% of the badgers, but by none of the bank voles. | 2002 | 12023924 |
| cross-protection against challenge with puumala virus after immunization with nucleocapsid proteins from different hantaviruses. | hantaviruses are rodent-borne agents that cause hemorrhagic fever with renal syndrome or hantavirus pulmonary syndrome in humans. the nucleocapsid protein (n) is relatively conserved among hantaviruses and highly immunogenic in both laboratory animals and humans, and it has been shown to induce efficient protective immunity in animal models. to investigate the ability of recombinant n (rn) from different hantaviruses to elicit cross-protection, we immunized bank voles with rn from puumala (puuv) ... | 2002 | 12050380 |
| assessing the genotoxicity of chronic environmental irradiation by using mitochondrial dna heteroplasmy in the bank vole (clethrionomys glareolus) at chornobyl, ukraine. | this study was designed to investigate whether or not chronic exposure to chornobyl radiation poses a molecular genetic risk to mammals by examining a relatively rapidly evolving genetic system, mitochondrial dna (mtdna). more mtdna mutations (approximately 19%) and an increase in mtdna heteroplasmy (approximately 5%) occurred in the cytochrome b gene of an exposed mother-embryo set when compared to a relatively unexposed mother-embryo set. however, this increase was not statistically significan ... | 2002 | 12069310 |
| frequency distributions of 137cs in fish and mammal populations. | we collected fish and mammals in several radioactively contaminated locations in the chornobyl exclusion zone and analyzed them for 137cs content. frequency distributions were built for populations of channel catfish, yellow-necked mice and bank voles. we combined our data with similar data from several other studies to demonstrate the relationship between the standard deviations and means of 137cs of fish and mammal populations. the frequency distributions of 137cs in populations of fish and ma ... | 2002 | 12113506 |
| spatial and temporal aspects of urban transmission of echinococcus multilocularis. | high prevalences of echinococcus multilocularis have been reported from foxes of the city of zurich, switzerland. in order to characterize transmission in urban areas, a coproantigen elisa was evaluated for diagnosing the infection in fox faecal samples collected in the environment. in addition, trapped rodents were investigated for the presence of metacestodes. faecal samples could reliably be classified as being of fox origin by assessing physical properties as shown by the different parasite ... | 2002 | 12118719 |
| reproductive system: aromatase and estrogens. | the cytochrome p450 aromatase (p450arom) is the terminal enzyme responsible for the formation of estrogens from androgens. in the rat testis we have immunolocalized the p450arom not only in leydig cells but also in germ cells and especially in elongated spermatids. related to the stage of germ cell maturation, we have shown that the level of p450arom transcripts decreases, it is much more abundant in pachytene spermatocytes (ps) than in mature germ cells whereas the aromatase activity is two- to ... | 2002 | 12161013 |
| molecular analysis of three ljungan virus isolates reveals a new, close-to-root lineage of the picornaviridae with a cluster of two unrelated 2a proteins. | ljungan virus (lv) is a suspected human pathogen recently isolated from bank voles (clethrionomys glareolus). in the present study, it is revealed through comparative sequence analysis that three newly determined swedish lv genomes are closely related and possess a deviant picornavirus-like organization: 5' untranslated region-vp0-vp3-vp1-2a1-2a2-2b-2c-3a-3b-3c-3d-3' untranslated region. the lv genomes and the polyproteins encoded by them exhibit several exceptional features, such as the absence ... | 2002 | 12163611 |
| prevalence and abundance of cryptosporidium parvum and giardia spp. in wild rural rodents from the mazury lake district region of poland. | prevalence and abundance of cryptosporodium parvum and giardia spp. were studied in 3 species of rodents from forests and abandoned agricultural fields in n.e. poland (clethrionomys glareolus n = 459; microtus arvalis n = 274; apodemus flavicollis n = 209). overall prevalence was consistently higher in the voles compared with a. flavicollis (70.6, 73.0 and 27.8% respectively for c. parvum and 93.9, 96.3 and 48.3% respectively for giardia spp.). prevalence and abundance of infection also varied m ... | 2002 | 12166517 |
| [epidemic nephropathy. an important differential diagnosis of acute renal failure in reutlingen, an endemic area]. | hantavirus ("epidemic") nephropathy (hn), or hemorrhagic fever with renal syndrome (who nomenclature), is an infection caused by strains (e.g. puumala) of hantavirus, which is often accompanied by acute renal failure. although its typical symptomatology has been fully reported, it is rarely included in the differential diagnosis of renal nephropathy. this study investigated whether, in the presence of typical symptoms, specific search for a certain constellation of laboratory values in associati ... | 2002 | 12183800 |
| demographic factors associated with hantavirus infection in bank voles (clethrionomys glareolus). | the bank vole (clethrionomys glareolus) is the natural reservoir of puumala virus (puuv), a species in the genus hantavirus. puuv is the etiologic agent of nephropathia epidemica, a mild form of hemorrhagic fever with renal syndrome. factors that influence hantavirus transmission within host populations are not well understood. we evaluated a number of factors influencing on the association of increased puuv infection in bank voles captured in a region in northern sweden endemic for the virus. l ... | 2002 | 12194768 |
| behavioral, physiologic, and habitat influences on the dynamics of puumala virus infection in bank voles (clethrionomys glareolus). | populations of bank voles (clethrionomys glareolus) were monitored during a 4-year study in southern belgium to assess the influence of agonistic behavior, reproductive status, mobility, and distribution of the rodents on the dynamics of puumala virus (abbreviation: puuv; genus: hantavirus) infection. concordance was high between data from serologic testing and results of viral rna detection. wounds resulting from biting or scratching were observed mainly in adult rodents. hantavirus infection i ... | 2002 | 12194769 |
| mycobacterium microti infection (vole tuberculosis) in wild rodent populations. | mycobacterium microti (vole tuberculosis) infections in small wild mammals were first described more than 60 years ago in several populations in great britain. few studies of vole tuberculosis have been undertaken since then, and little is known about the relationship between m. microti isolates originating from different populations or at different times or of the prevalence of this infection in wild rodent populations, despite human cases of m. microti infections being increasingly reported. i ... | 2002 | 12202566 |
| lack of a distinct gradient in biomarker responses in small mammals collected at different distances from a highway. | this study describes biomarker effects in small mammals exposed to traffic emissions. animals were collected at 10-50 m (site 1), 150-200 m (site 2), and 5 km (site 3) from a very busy highway (a2). to distinguish between routes of exposure, strictly carnivorous common shrews ( sorex araneus) and predominantly herbivorous bank voles ( clethrionomys glareolus) were collected. as a measure of exposure to polycyclic aromatic hydrocarbons (pahs), aromatic dna adduct levels were determined by (32)p-p ... | 2002 | 12202932 |
| hormonal manipulation of offspring number: maternal effort and reproductive costs. | we used exogenous gonadotropin hormones to physiologically enlarge litter size in the bank vole (clethrionomys glareolus). this method allowed the study design to include possible production costs of reproduction and a trade-off between offspring number and body size at birth. furthermore, progeny rearing and survival and postpartum survival of the females took place in outdoor enclosures to capture salient naturalistic effects that might be present during the fall and early winter. the aim of t ... | 2002 | 12206251 |
| characterisation of dna probes for the analysis of metallothionein gene expression in the bank vole (clethrionomys glareolus). | dna probes have been developed for subsequent use in monitoring the exposure of animals to heavy metal pollution in terrestrial environments using metallothionein (mt) gene expression in the bank vole (clethrionomys glareolus). three different bank vole sequences were characterised corresponding to the cdna and the genomic dna for mt-i and the genomic dna for mt-ii. nucleotide sequence analysis indicates that the coding sequences of the bank vole mt-i and mt-ii genes exhibit a very high degree o ... | 2002 | 12222609 |
| yeast-expressed puumala hantavirus nucleocapsid protein induces protection in a bank vole model. | hantaviruses are rodent-borne agents that cause severe human diseases. the coding sequences for the authentic and a his-tagged puumala hantavirus (puuv) nucleocapsid (n) protein were expressed in yeast (saccharomyces cerevisiae). n-specific monoclonal antibodies demonstrated native antigenicity of the two proteins. all bank voles vaccinated with the his-tagged n protein in freund's adjuvant (n=12) were defined as completely protected against subsequent virus challenge, based on the absence of vi ... | 2002 | 12297397 |
| rodent host specificity of european hantaviruses: evidence of puumala virus interspecific spillover. | in order to investigate rodent host specificity of european hantaviruses, experimental infection of colonized and wild-trapped rodents was performed. in addition to the natural rodent reservoir, clethrionomys glareolus, puumala hantavirus (puuv) could infect colonized microtus agrestis and lemmus sibiricus, but not syrian hamsters or balb/c mice. neither c. glareolus, nor m. agrestis, could be readily infected by tula hantavirus (tulv). wild-trapped apodemus flavicollis and a. agrarius, the natu ... | 2002 | 12376967 |
| hantaviruses in estonia. | human serum samples collected from healthy individuals in 14 counties were screened by elisa in order to investigate the presence of hantavirus infections in estonia. out of 1,234 serum samples, 124 were found positive for hantavirus-specific igg and were subsequently serotyped by a focus reduction neutralization test. a total of 112 samples neutralized at least one of the examined hantaviruses-puumala (puuv), saaremaa (saav), dobrava (dobv), hantaan, and seoul viruses-and thereby, the focus red ... | 2002 | 12376968 |
| evidence for a relationship between cage stereotypies and behavioural disinhibition in laboratory rodents. | cage stereotypies-abnormal, repetitive, unvarying and apparently functionless behaviours-are common in many captive animals, sometimes resulting in self-injury or decreased reproductive success. however, a general mechanistic or neurophysiological understanding of cage stereotypies has proved elusive. in contrast, stereotypies in human mental disorder, or those induced by drugs or brain lesions, are well understood, and are thought to result from the disinhibition of behavioural selection by the ... | 2002 | 12385793 |
| dinara - new natural focus of hemorrhagic fever with renal syndrome in croatia. | to investigate the characteristics and determine risk factors for hantanvirus infection in natural focus of hemorrhagic fever with renal syndrome (hfrs) on the dinara mountain, where outbreak of disease emerged among croatian soldiers in 1995, and to describe the features of hfrs acquired on the dinara mountain and determine the scale of the largest hfrs epidemic so far in croatia. | 2002 | 12402400 |
| epidemiologic characteristics and military implications of hemorrhagic fever with renal syndrome in croatia. | to analyze epidemiologic characteristics of hemorrhagic fever with renal syndrome in croatia, including military implications of the disease and measures for its prevention. | 2002 | 12402401 |
| prevalence of coinfection with francisella tularensis in reservoir animals of borrelia burgdorferi sensu lato. | studies on lyme borreliosis and other tick-borne zoonoses in the austrian and slovakian borderland, a region endemic for tularemia, revealed a relatively high prevalence of infection with borrelia burgdorferi s.l. and francisella tularensis in small terrestrial mammals, as well as in the ticks, during a one-year survey. the occurrence of coinfection with the agents of lyme borreliosis and tularemia was assessed in different species of rodents. | 2002 | 12422587 |
| cadmium accumulation in fetus and placenta of bank voles ( clethrionomys glareolus, schreber 1780). | 2002 | 12428159 | |
| distribution of hantavirus foci in belgium. | during 1999 and 2000, we performed rodent captures on 15 sites all over belgium to evaluate the presence of hantaviruses in local rodent populations. viral antibody and rna detection was performed by elisa/focus reduction neutralisation test and rt-pcr, respectively. we found hantavirus-positive rodents on 13 out of 15 trapping sites and 3 rodent species were found positive for hantavirus infection. apart from puumala virus that was carried by clethrionomys glareolus, 2 additional rodent species ... | 2002 | 12443796 |
| properties of bacillus thuringiensis isolated from bank voles. | to assess the properties of b. thuringiensis naturally occurring in the intestines of bank voles. | 2003 | 12492924 |
| puumala hantavirus infection in humans and in the reservoir host, ardennes region, france. | we compared the occurrence of nephropathia epidemica cases, over a multi-annual population cycle, in northeastern france with the hantavirus serology for bank voles captured in the same area. we discuss hypotheses to explain the pattern of infection in both humans and rodents and their synchrony. | 2002 | 12498675 |
| [detection of natural foci of babesiosis and granulocytic ehrlichiosis in russia]. | the use of microscopy, infection of golden hamsters and the polymerase chain reaction made it possible to find out that about 30% of common red-backed voles (clethrionomys glareolus), inhabiting the taiga forests of the southern part of the western urals (the chusovskoi district of the perm region), were infected with babesia microti and simultaneously (a third of them) with ehrlichia (cytoecetes) phagocytophila, the causative agent of granulocytic ehrlichiosis. the sequencing of 18s rdna of str ... | 2002 | 12506622 |
| [genetic efficacy of low doses of ionizing radiation in chronically-irradiated small mammals]. | earlier we have established the genetic effects of low dose chronic irradiation in bank vole (somatic and germ cells, embryos), in pond carp (fertilized eggs, embryos, fry) and in laboratory mice (somatic and germ cells) in the range of doses from near-background to 10 cgy. these low dose effects observed in mammals and fish are not expected from extrapolation of high dose experiments. for understanding reasons this discrepancy the comparative analysis of genetic efficiency of low dose chronic i ... | 2002 | 12530144 |
| seasonal dynamics of anaplasma phagocytophila in a rodent-tick (ixodes trianguliceps) system, united kingdom. | we investigated the reservoir role of european wild rodents for anaplasma phagocytophila using polymerase chain reaction (pcr) analysis of blood collected from individually tagged rodents captured monthly over 2 years. the only tick species observed in the woodland study site was ixodes trianguliceps, and ruminant reservoir hosts were not known to occur. a. phagocytophila infections were detected in both bank voles and wood mice but were restricted to periods of peak nymphal and adult tick activ ... | 2003 | 12533283 |
| the wood mouse is a natural host for murid herpesvirus 4. | infection of laboratory mice by the murid herpesvirus 4 (mhv-4) is a much studied model system for gammaherpesvirus pathogenesis. little, however, is known about its natural host range, epidemiology and pathogenesis outside the laboratory. we have studied mhv-4 infection in free-living murids in the uk. using a combination of serology and pcr analysis, we found that mhv-4 was endemic in wood mice (apodemus sylvaticus) but not in two species of voles (clethrionomys glareolus, microtus agrestis). ... | 2003 | 12533706 |
| a comparative analysis of the heavy metal loading of small mammals in different regions of bulgaria i: monitoring points and bioaccumulation features. | data on liver and body copper, zinc, lead, and cadmium content of small mammals (rodents and insectivorous) were collected and analyzed. data comparisons were performed in two aspects: (1) points and years of monitoring; (2) monitor species bioaccumulations. specific bioaccumulation features were observed in some of the monitor species. a method for comparative evaluation of heavy metal loads in the different species is proposed using data for liver and body contamination. the loads of clethrion ... | 2003 | 12550095 |
| a comparative analysis of the heavy metal loading of small mammals in different regions of bulgaria ii: chromosomal aberrations and blood pathology. | heavy metal content was monitored in small mammals inhabiting mountain ecosystems and two industrial polluted regions in bulgaria. rodents (microtus arvalis, m. rossiaemeridionalis, clethrionomys glareolus, pitymys subterraneus, chionomys nivalis, apodemus flavicollis, a. sylvaticus, and mus macedonicus) were used as zoomonitors. pathological changes in chromosome status, hematological indices, and blood cell morphology were analyzed in the context of heavy metal bioaccumulation. significant cor ... | 2003 | 12550096 |
| an iron-rich diet protects the liver and kidneys against cadmium-induced injury in the bank vole (clethrionomys glareolus). | the objective of this study was to determine whether supplemental dietary iron (fe) would protect against cadmium (cd)-induced injury in the liver and kidneys of bank voles. the rodents were provided, for 6 weeks, fe-adequate (60-80 microg/g) and fe-enriched (250-270 microg/g) diets containing 0.05 (control), 40, and 80 microg cd/g. histological examinations and analyses of cd, cd bound and not bound to metallothionein (mt), fe, and lipid peroxidation in liver and kidneys were carried out. the f ... | 2003 | 12550097 |
| bartonella infection in sylvatic small mammals of central sweden. | sylvatic small mammals were captured in rural habitats near uppsala, sweden, to measure the prevalence of bartonella infections, characterize bacterial isolates and identify their host range, and increase our understanding of host-pathogen ecology. during 7 nights of trapping at 3 localities, 236 small mammals were captured (trap success 30%). bartonella were isolated from bloods of apodemus flavicollis (19 of 110 tested), apodemus sylvaticus (6/25), clethrionomys glareolus (9/60), microtus agre ... | 2003 | 12613756 |
| association of borrelia afzelii with rodents in europe. | borrelia burgdorferi sensu lato (s.l.) is maintained in nature by complex zoonotic transmission cycles, involving a large variety of vertebrates as hosts and hard ticks of the genus ixodes as vectors. recent studies suggest that the genospecies of b. burgdorferi s.l. and sometimes their subtypes are propagated by different spectra of hosts, mainly birds and rodents. in order to test the concept of host-association, we analysed the relationships between borrelia genospecies, rodent hosts and i. r ... | 2003 | 12613759 |
| [structure and seasonal dynamics of the biotic community ectoparasites of the bank vole in the il'men'-volkhov lowland]. | a biodiversity, seasonal dynamics and parasite load of a single individual and local population of the bank vole (clethrionomys glareolus) were studied in coniferous and mixed forests of the ilmen-volkhov lowland (neighborhood of oskuy village, chudovo region, novgorod province) in the period from june 1999 till may 2002. the gero's traps were used for collecting the host. lines of traps stood in each place during 3-5 days and were checked twice a day. trapping of micromammalian hosts and collec ... | 2002 | 12624960 |
| the molecular evidence of babesia microti infection in small mammals collected in slovenia. | in europe, the zoonotic cycle of babesia microti has not been determined so far. recently, b. microti was detected in ixodes ricinus ticks in slovenia by using molecular methods. in order to investigate the mammalian hosts of b. microti in slovenia we collected 261 small mammals representing 11 species. they were tested for the presence of babesial parasites with a pcr assay based on the nuclear small subunit rrna gene (nss-rdna). the bank vole (clethrionomys glareolus) and yellow-necked mouse ( ... | 2003 | 12636348 |
| [detection of hantavirus antigen in rodents in the czech republic]. | the work is based on the hitherto implemented examinations of lungs of rodents from the territory of the czech republic for the presence of hantavirus antigen. for detection of a species specific antigen the elisa set hantagnost from the poliomyelitis institute in moscow was used. a total of 1494 micromammalia of 15 species caught in 1991-2001 were examined. the hantavirus antigen was detected in the lungs of 101 individuals (6.8%) whereby representatives of the species microtus arvalis predomin ... | 2003 | 12647557 |
| molecular characterization of m1146, an american isolate of ljungan virus (lv) reveals the presence of a new lv genotype. | ljungan virus (lv) is a suspected human pathogen recently isolated from bank voles in sweden. this study describes the genetic characterization of a virus, m1146, which was isolated in 1962 from another vole species (microtus montanus), trapped in oregon, usa. based on antigenic properties, m1146 was postulated previously as a putative member of the family picornaviridae: the near complete genomic sequence verifies that m1146 is a member of the picornaviridae, most closely related to lvs isolate ... | 2003 | 12655084 |
| distribution of puumala hantavirus in denmark: analysis of bank voles (clethrionomys glareolus) from fyn and jutland. | the majority of hantaviral infections in denmark since 1957 have occurred on the island of fyn. we have recently shown the presence of puumala hantavirus (puuv) in bank voles (clethrionomys glareolus) on fyn. to learn more about the distribution and prevalence of puuv in denmark, 310 small mammals, belonging to six rodent and two insectivore species, were trapped in four localities on fyn and three localities on the jutland peninsula (mainland denmark), where only a few cases of nephropathia epi ... | 2002 | 12656129 |
| complementary approaches demonstrate that cellular aromatization in the bank vole testis is related to photoperiod. | a growing body of evidence indicates that germ cells, at least in several mammalian species, are responsible for estrogen formation since they possess active aromatase. in seasonally breeding rodent, the bank vole, the length of photoperiod seems to be the primary environmental factor regulating annual changes in the reproductive activity. however, in this species gonadal steroidogenesis is still not well understood, neither the site of aromatization in testicular cells. in the bank vole testis, ... | 2003 | 12685558 |
| landscape effects on temporal and spatial properties of vole population fluctuations. | populations of northern small rodents have previously been observed to fluctuate in spatial synchrony over distances ranging from tens to hundreds of kilometers between sites. it has been suggested that this phenomenon is caused by common environmental perturbations, mobile predators or dispersal movements. however, very little focus has been given to how the physical properties of the geographic area over which synchrony occurs, such as landscape composition and climate, affect spatial populati ... | 2003 | 12698342 |
| immunolocalization of pthrp in the sublingual glands of three mammals. | the present study deals with immunohistochemical localization of pthrp in sublingual glands of white mouse, bank vole, and common vole. pthrp immunoreactivity was observed in epithelial cells of striated, interlobular and main excretory ducts of the salivary glands in all the three animal species tested. however, we found no positive reaction for pthrp in epithelial cells of the intercalated ducts. in striated duct cells, the reaction intensity was species-dependent. in bank vole and common vole ... | 2003 | 12705476 |
| accumulation of lead, zinc, and cadmium in a wild population of clethrionomys glareolus from an abandoned lead mine. | lead, zinc, and cadmium were determined in a range of tissues from wild populations of bank voles (clethrionomys glareolus) trapped on an abandoned metalliferous mine site and a reference site. estimated dietary intakes indicated that animals were exposed to elevated levels of all three metals at the mine site, and this was generally reflected in metal residues in body tissues. lead concentrations were significantly higher in all tissues of animals from the mine compared to the reference site, w ... | 2003 | 12712302 |
| the neuronal structure of the inferior colliculus in the bank vole (clethrionomys glareolus)--golgi and nissl studies. | the inferior colliculus (ic) of the bank vole is made up of 3 nuclei: the external and pericentral nucleus, which are located on the outer border of the ic, and the central nucleus, which is the largest part of ic and shows a laminated structure. on the basis of various morphological criteria 5 types of neurons have been distinguished in the bank vole ic: 1. the rounded cells (perikarya 10-15 microm) with 2-4 primary dendritic trunks. the dendritic tree has a spindle-like shape. the axon emerges ... | 2002 | 12725500 |
| the long-term effect of cadmium exposure through food on the postnatal development of the bank vole (clethrionomys glareolus schreber, 1780). | cadmium is well known for its toxicity to the animal body. however, its effect on pregnancy and the development of young animals is still not well understood. this study examined such effects, using bank voles captured from the wild to make the results closer to those which could be expected in the natural environment. one group of animals was fed 7 microg g(-1) cadmium in the food, a second 35 microg g(-1), and a third no cadmium, as a control. the concentrations of cadmium in the whole bodies ... | 2002 | 12729167 |
| the effect of heavy metal accumulation on metallothionein content in selected tissues of bank voles and yellow-necked mice caught near a steelworks and zinc smelter. | the effect of cadmium, zinc, and copper accumulation on metallothionein content in the selected tissues of bank voles and yellow-necked mice trapped near the sendzimir steelworks in krakow and the zinc smelter in bukowno were analysed. the borecka forest was chosen as a control area. the highest cadmium concentration, 32.98 microg g(-1) dry weight, was detected in the kidneys of the bank voles caught in the bukowno area. zinc and copper concentrations in the tissues did not exceed the critical v ... | 2002 | 12729168 |
| exposure of small mammals, in particular the wood mouse apodemus sylvaticus, to pesticide seed treatments. | field exposure of small mammals to fungicide-treated wheat seed was investigated over three weeks following drilling on fields near york, united kingdom. seed consumption by small mammals trapped on and immediately adjacent to the drilled fields was quantified by measuring the amount of seed in the stomach. in addition, exposure to one seed-treatment, fluquinconazole, was quantified by measuring residues of the fungicide in the stomach, liver, and intestine. the wood mouse, apodemus sylvaticus, ... | 2003 | 12729225 |
| effects of postnatal stress on the development of type 1 diabetes in bank voles (clethrionomys glareolus). | wild bank voles (clethrionomys glareolus) kept in the laboratory under barren housing conditions develop high incidences of type 1 diabetes mellitus due to beta cell-specific lysis in association with the appearance of gad65, ia-2, and insulin autoantibodies. wild-caught and immediately analyzed voles show no histological signs of diabetes, and the disease may therefore be induced by circumstances related to the housing of the animals in captivity. we tested the possibility that postnatal stress ... | 2008 | 12745667 |
| development of type 1 diabetes in wild bank voles associated with islet autoantibodies and the novel ljungan virus. | wild bank voles (clethrionomys glareolus) may develop diabetes in laboratory captivity. the aim of this study was to test whether bank voles develop type 1 diabetes in association with ljungan virus. two groups of bank voles were analyzed for diabetes, pancreas histology, autoantibodies to glutamic acid decarboxylase (gad65), ia-2, and insulin by standardized radioligand-binding assays as well as antibodies to in vitro transcribed and translated ljungan virus antigens. group a represented 101 tr ... | 2003 | 12745669 |
| aromatase expression and role of estrogens in male gonad : a review. | the ability of the testis to convert irreversibly androgens into estrogens is related to the presence of a microsomal enzymatic complex named aromatase, which is composed of a specific glycoprotein, the cytochrome p450 aromatase (p450arom) and an ubiquitous reductase. the aromatase gene is unique in humans and contained 18 exons, 9 of them being translated. in the rat testis we have immunolocalized the p450arom not only in leydig cells but also in germ cells and especially in elongated spermatid ... | 2003 | 12747806 |
| effect of photoperiod on the distribution patterns of androgen receptors and steroid hormone concentrations in ovaries of bank voles. | cellular distribution patterns of the androgen receptor in ovaries of female bank voles, born and reared in long (18:6; ld) or short (6:18; sd) photoperiods, have been studied to understand effects of androgens in female gonads. the photoperiod is one of the most important factors in bank voles, which are seasonal breeders, that regulates both morphology and hormonal function of the ovary. androgen receptors were visualized immunocytochemically, using a specific monoclonal antibody against andro ... | 2003 | 12831169 |
| prenatal stress affects the rate of sexual maturation and attractiveness in bank voles. | field studies reveal that bank vole females' mobility and aggression increase during pregnancy. here we investigated the reaction of pregnant females to social stress evoked by short but frequent meetings with another female at the same stage of pregnancy. the stress neither evoked pregnancy termination nor affected pregnancy duration but had a long-term effect on the reproductive activity of the offspring. prenatal stress reduced the rate of sexual maturation of voles as estimated at the age of ... | 2003 | 12834803 |