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cosmetics and herbal remedies with compositae plant extracts - are they tolerated by compositae-allergic patients?compositae-sensitive patients are routinely warned against topical use of compositae-containing cosmetics and herbal remedies. however, the risk of elicitation of dermatitis in presensitized persons is unknown.200818154553
retrospective analysis of 736 implants inserted without antibiotic therapy.the routine use of antibiotics in oral implant treatment seems to be widespread. the principle of antibiotic prophylaxis before oral surgical procedures in patients at risk for endocarditis or in those who are severely immunocompromised is well established. antibiotic therapy in conjunction with implant surgery in fit patients and its correlation with failure and success rates remains poorly documented, however. the debate regarding overprescription of antibiotics raises the need for a critical ...200717954332
a novel melanin inhibitor: hydroperoxy traxastane-type triterpene from flowers of arnica montana.we isolated a novel inhibitor of melanin biosynthesis from the flowers of arnica montana l. (compositae), and identified it as a traxastane-type triterpene (3beta,16beta-dihydroxy-21alpha-hydroperoxy-20(30)-taraxastene) [1] by means of 1d or 2d-nmr and liquid chromatography/high-resolution mass spectrometry (lc-hr-ms). compound [1] at the concentration of 0.53 mum completely inhibited melanin accumulation in cultured b16 melanoma cells. it is one of the most potent among known plant inhibitors o ...200717473428
sesquiterpene lactone content in leaves of in vitro and field cultivated arnica montana.on the basis of gc and gc/ms analyses we report on the full qualitative and quantitative sesquiterpene lactone (stl) content of in vitro cultivated a. montana plantlets consisting of helenalin and 11alpha,13-dihydrohelenalin esters in approximately equal amounts. the accumulation of stl was shown to be correlated with tissue differentiation in the above-ground parts. the seasonal variation of stl content in leaves of a. montana cultivated in the proving field was investigated. changes in the com ...199817253241
homeopathic arnica montana for post-tonsillectomy analgesia: a randomised placebo control trial.to evaluate the efficacy of homeopathic arnica in reducing the morbidity following tonsillectomy.200717227743
homeopathic arnica therapy in patients receiving knee surgery: results of three randomised double-blind trials.we investigated the effectiveness of homeopathic arnica montana on postoperative swelling and pain after arthroscopy (art), artificial knee joint implantation (akj), and cruciate ligament reconstruction (clr).200617105693
immunologically active polysaccharides of arnica montana cell cultures.from the nutrition medium of arnica montana cell cultures two homogeneous polysaccharides, an acidic arabino-3,6-galactan-protein with mean mr of 100,000 and a neutral fucogalactoxyloglucan with mean mr of 22,500 have been isolated by deae-sepharose cl-6b and sephacryl s-400 column chromatography. their structures were elucidated mainly by methylation analysis, partial acidic and enzymatic hydrolysis and 13c nmr spectroscopy. the fucogalactoxyloglucan shows a pronounced enhancement of phagocytos ...19911367382
postpartum homeopathic arnica montana: a potency-finding pilot study. 19902102159
development and stability of semisolid preparations based on a supercritical co2 arnica extract.conventional herbal drug preparations (hdp) based on arnica montana l. have a low content of the active principles, sesquiterpene lactones, which show poor stability and low physical compatibility in semisolid formulations. recently, an innovative supercritical carbon dioxide (co2) extract with high sesquiterpene content has been marketed. development of six semisolid preparations (cetomacrogol, polysorbate 60, polawax, anphyphil, natrosol and sepigel) based on this innovative co2 extract is dis ...200616457981
[on the effectiveness of the homeopathic remedy arnica montana].arnica montana is a homeopathic remedy often prescribed after traumata and injuries.200516425108
effect of homeopathic arnica montana on bruising in face-lifts: results of a randomized, double-blind, placebo-controlled clinical trial.to design a model for performing reproducible, objective analyses of skin color changes and to apply this model to evaluate the efficacy of homeopathic arnica montana as an antiecchymotic agent when taken perioperatively.201216415448
altitudinal variation of secondary metabolite profiles in flowering heads of arnica montana cv. arbo.the altitudinal variation on the contents of secondary metabolites in flowering heads of arnica montana was assessed. plants of a. montana cultivar arbo were grown in nine experimental plots at altitudes between 590 and 2230m at mount patscherkofel near innsbruck/austria. the total contents of sesquiterpene lactones and flavonoids were not positively correlated with the altitude of the growing site. however, the proportion of flavonoids with vicinal free hydroxy groups in ring b to flavonoids la ...200616405933
methylated flavonoids from arnica montana and arnica chamissonis.from the flowers of arnica chamissonis less, subsp. foliosa var. incana, the methylated flavonoids acacetin, pectolinarigenin, hispidulin, jaceosidin, 6-methoxykaempferol, and betuletol have been isolated and identified by spectroscopic methods. except for acacetin, the same flavonoids were identified in the flowers of arnica montana l. betuletol was found for the first time in the family of asteraceae.198417340267
6-o-isobutyryl-tetrahydrohelenalin from the flowers of arnica montana.from the flowers of arnica montana l., the helenanolides 6- o-isobutyryl-tetrahydrohelenalin and 2beta-ethoxy-6- o-isobutyryl-2,3-dihydrohelenalin were isolated and their structures established by spectroscopic methods.198417340245
metronidazole (flagyl) and arnica montana in the prevention of post-surgical complications, a comparative placebo controlled clinical trial.a double blind trial, was designed, in which 118 patients undergoing the removal of impacted wisdom teeth were randomly divided into the following groups; 41 patients received metronidazole, 39 patients received arnica montana, 38 patients received the placebo. metronidazole was more effective in pain control than arnica (p less than 0.001) and placebo (p less than 0.01). it prevented swelling better than arnica (p less than 0.01) and placebo (p less than 0.05) and was more effective in promotin ...19846365158
homeopathic treatment in emergency medicine: a case series.following a multiple-casualty construction disaster in israel, members of the center of integrated complementary medicine joined in the emergency activity of the shaare zedek medical center. they administered homeopathic treatment to injured patients to supplement conventional orthopaedic treatment. this was to our knowledge the first time that complementary medicine had been used officially in conjunction with conventional medicine in an emergency situation. our objective is to report and summa ...200312587994
arnica montana gel in osteoarthritis of the knee: an open, multicenter clinical trial.this open multicenter trial investigated the safety and efficacy of an arnica montana fresh plant gel, applied twice daily, in 26 men and 53 women with mild to moderate osteoarthritis (oa) of the knee. after 3 and 6 weeks, significant decreases in median total scores on the western ontario and mcmaster universities osteoarthritis index (womac) were evident in the intention-to-treat and per-protocol populations (both p < .0001). scores on the pain, stiffness, and function subscales also showed si ...200612539881
the seamy side of natural medicines: contact sensitization to arnica (arnica montana l.) and marigold (calendula officinalis l.).medical remedies of plant origin have gained increasing popularity in recent years. both anaphylactic and eczematous allergic reactions are on the rise, accordingly. arnica and marigold, both of the compositae family, are in widespread use, but only limited data are available on their allergenic potential. we tested 443 consecutive patients, in addition to the european standard and other series, with compositae mix, sesquiterpene lactone mix, arnica, marigold, and propolis. 5 subjects ( approxim ...200111722485
[identification of carotenoids in arnica montana]. 19734732114
[fatty acids of the essential oil from leaves of arnica montana and arnica longifolia]. 19724403598
[a still mysterious medicinal plant, arnica montana l]. 19714927860
[arnica montana l]. 19685681721
[cultivation experiments with arnica species. ii. vegetative propagation of arnica montana l]. 19675603484
[contribution to the knowledge of the substances contained in arnica montana l]. 19665926222
[therapeutic experiences with arnica montana]. 196514263823
[some new constituents from the roots of arnica montana]. 196313987185
[arnica montana as a medicinal plant]. 195913834712
[arnica montana as a medicinal plant]. 195913676103
[study on the constituents of arnica montana l]. 195613328059
[cholagogue action of arnica montana]. 200614391392
[arnica montana mistaken for inula britannica]. 195413177151
[possible testing of tinctures of arnica montana l..]. 195413198192
[arnica montana. iii]. 195313073437
[arnica; arnica montana. ii]. 195313073424
[cultivation of arnica montana]. 200913051137
[arnica (arnica montana)]. 195313073403
[arnica montana]. 195212983199
[pharmacology of arnica montana l]. 194915406032
potential for danger with arnica montana. 200111293536
efficacy of homeopathic arnica: a systematic review of placebo-controlled clinical trials.the efficacy of homeopathic remedies has remained controversial. the homeopathic remedy most frequently studied in placebo-controlled clinical trials is arnica montana.19989820349
[selenium as a modifier of antioxidant protection and lipid peroxidation in microclones of arnica montana l. as affected by c-range ultraviolet rays].selenium was studied for its effect on the node components of antioxidant protection of plants irradiated by uv of c-range. it is shown that selenium modifies the uv action of c-range and decreases the oxidation of sh-groups, increases activity of superoxide dismutase and glutathione peroxidase and decreases the accumulation of the end product of peroxidation: malondialdehyde.20159606837
helenalin, an anti-inflammatory sesquiterpene lactone from arnica, selectively inhibits transcription factor nf-kappab.alcoholic extracts prepared form arnicae flos, the collective name for flowerheads from arnica montana and a. chamissonis ssp. foliosa, are used therapeutically as anti-inflammatory remedies. the active ingredients mediating the pharmacological effect are mainly sesquiterpene lactones, such as helenalin, 11alpha,13-dihydrohelenalin, chamissonolid and their ester derivatives. while these compounds affect various cellular processes, current data do not fully explain how sesquiterpene lactones exer ...19979348104
mekc as an improved method to detect falsifications in the flowers of arnica montana and a. chamissonis.arnica montana and arnica chamissonis ssp. foliosa flowers are often adultered by blending them with those from heterotheca inuloides. tlc, hplc, and tsp lc/ms have been proposed to detect this kind of falsification. a new method based on micellar electrokinetic chromatography (mekc) has been developed. this procedure permits us to characterize rapidly each drug and to detect easily falsifications from h. inuloides in arnica drugs.199417236057
[the effects of arnica montana on blood coagulation. randomized controlled trial].the purpose of this study, which took the form of a two-period cross-over clinical trial, was to determine whether a homeopathic substance, arnica montana, significantly decreased bleeding time (simplate ii) and to describe its impact on various blood coagulation tests. it was not shown that this substance had a significant impact on various parameters of blood coagulation in healthy volunteers in the period immediately following administration [corrected].19937903572
helenalin acetate in in vitro propagated plants of arnica montana.propagated "in vitro" shoots and plantlets of arnica montana l. (asteraceae) have been shown to produce sesquiterpene lactones, i.e. helenalin and 11,13-dihydrohelenalin esters. the compounds were detected in green organs only; roots of the plantlets contained no sesquiterpene lactones. the helenalin acetate content in leaves of the plantlets (0.073% dry wt) was 4-times higher than in proliferated shoots (0.016% dry wt). the best rate of shoot multiplication was achieved on ms medium, supplement ...199317230337
tussilagine and isotussilagine: two pyrrolizidine alkaloids in the genus arnica1.in flowerheads of arnica montana, a. chamissonis ssp. foliosa, a. amplexicaulis, and a. sachalinensis, traces of the non-toxic pyrrolizidine alkaloids tussilagine and isotussilagine were detected. their identity was unambiguously confirmed by direct comparison (tlc, gc, gc/ms) with the authentic samples.199217226521
new flavonoid glycosides from arnicae flos dab 91.five flavonoid glycosides were identified from flowers of arnica montana, ten from a. chamissonis subsp. foliosa var. incana. the structures were established on the basis of acid hydrolysis and spectral data (uv, nmr, ms) as the 7-beta-glucosides of pectolinarigenin, apigenin, and chrysoeriol; luteolin 3'- o-beta-glucoside; the 3-beta-glucuronides of kaempferol, isorhamnetin, and 6-methoxykaempferol; the 3,7-di-beta-glucosides of quercetin and patuletin; the 3-beta-glucosides of betuletol and qu ...199217226484
shoot tip culture of arnica montana for micropropagation.multiple shoots were regenerated from shoot tips of arnica montana on ms and b5 media supplemented with ba (1 mg/l) and naa (0.1 mg/l). sections of 1-2 mm in length cultured from in vitro germinated seedlings regenerated 7.7 (mean) shoots on the ms medium, whereas sections cultured from greenhouse plants regenerated 9.0 (mean) shoots on the b5 medium within 6 weeks. subsequent subcultures of shoots on the same media but without naa resulted in similar or lower multiplication rates (1.6 to 3.1 in ...199217226438
[effect of arnica d 30 during hard physical exertion. a double-blind randomized trial during the oslo marathon 1990].the effect of arnica montana on stiffness, restitution time and cell damage during hard physical exercise was evaluated in a randomized double blind trial during the oslo marathon. 36 participants were randomized: one group received arnica 10(-30) five pills twice daily for five days, starting the day before the event. the other group received placebo pills. blood tests were carried out before and immediately after finish, and after 48 and 72 hours. stiffness was evaluated on a visual analogue s ...19911780819
mycorrhizal plants of traditionally managed boreal grasslands in norway.this paper reports on the mycorrhizal status of 82 plant species growing in traditionally managed grasslands in three different locations in the boreal and boreo-nemoral vegetation zone in the eastern part of norway. seventy-four species were found to have arbuscular mycorrhiza (am). to our knowledge, we report am for the first time in achillea ptarmica, ajuga pyramidalis, alchemilla glaucescens, carex brunnescens, carex pallescens, crepis praemorsa, hieracium lactucella, rumex longifolius, scor ...200212072981
flavonoid glucuronides from the flowers of arnica montana1.five flavonoid glucuronides were identified from flowers of arnica montana l. the structures were established on the basis of total acid hydrolysis and spectral data (uv, (1)h-nmr, (13)c-nmr, mass) as 3- o-beta- d-glucuronides of quercetin, kaempferol, isorhamnetin, patuletin, and 6-methoxykaempferol. the last one is a new natural compound. this is the first report on glucuronides in the genus arnica. additionally, tricin and 3,5,7-trihydroxy-6,3',4'-trimethoxyflavone were identified. up to now ...198817265264
characterization of arnica montana l. flowers. 19873455222
flavonoid glycosides from arnica montana and arnica chamissonis.five flavonoid glycosides were identified from flowers of arnica montana, four from a. chamissonis subsp. foliosa var. incana. the structures were established on the basis of total acid hydrolysis and spectral data (uv, (1)h-nmr, (13)c-nmr, ms) as hispidulin 7- o-beta-glucoside, isorhamnetin 3- o-beta-glucoside, 3- o-beta- d-glucopyranosides of spinacetin, 6-methoxykaempferol and patuletin and querectin 3- o-(6''- o-acetyl)-beta- d-glucopyranoside. the latter compound can serve as distinctive ma ...198717269063
[immunostimulating action of polysaccharides (heteroglycans) from higher plants].from the water or alcaline-water extracts of echinacea purpurea (l.) moench. and -angustifolia dc., eupatorium cannabium l. and -perfoliatum l., chamomilla recutita l. rauscher, calendula officinalis l., baptisia tinctoria (l.) r. b., achyrocline satureioides dc., arnica montana l., sabal serrulata roem. et schult., and eleutherococcus (acanthopanax) senticosus maxim. polysaccharide fractions with molecular weights in the range of 25 000 to 500 000 and higher have been isolated, which, according ...19854052142
single-family versus multi-family introductions.the early success of plant introduction as a function of source material and habitat quality was tested in arnica montana to determine whether different introduction strategies could affect plant viability of the introduced population. plants originating from related (single-family introductions) and unrelated (multi-family introductions) individuals were introduced into undisturbed sites and into sites which were limed, turf cut, or both turf cut and limed. for four consecutive years, we analys ...200516163616
the effect of the homeopathic remedies arnica montana and bellis perennis on mild postpartum bleeding--a randomized, double-blind, placebo-controlled study--preliminary results.to evaluate the effect of arnica montana and bellis perennis on postpartum blood loss.200516036165
arnica montana and dosing of homeopathic medication. 200415220606
sesquiterpene lactones in arnica montana: a rapid analytical method and the effects of flower maturity and simulated mechanical harvesting on quality and yield.a rapid extraction, clean-up and rplc procedure suitable for routine quantitative analyses of sesquiterpene lactones (sls) in arnica montana is described. seven sls were isolated of which tigloyl and methacryloyl esters of helenalin made up over 50 % of the total. this method was applied to analyses of replicated samples of different flower parts, different stages of flower maturity, and herb from different harvest methods. the mean total sl levels were higher in the disk flowers (0.872 % w/w) t ...200414994196
arnica montana and homeopathic dosing guidelines. 200312900640
[immunostimulant action of polysaccharides (heteroglycans) from higher plants. preliminary communication].from the water or alcaline-water extracts of echinacea purpurea (l.) moench and -angustifolia dc., eupatorium cannabinum l. and -perfoliatum l., chamomilla recutita (l.) (rauscher), calendula officinalis l., baptisia tinctoria (l.) r.b., achyrocline satureoides dc., arnica montana l., sabal serrulata roem et schult. and eleutherococcus senticosus maxim. polysaccharide fractions with molecular weights in the range of 25 000 to 500 000 and higher have been isolated, which, according to the granulo ...19846541484
[helenalin- and 11,13-dihydrohelenalinester from flowers of arnica montana.].from the flowers of arnica montana l. 13 helenanolides were isolated and identified. they are shown to be 11,13-dihydrohelenalin ( 1), helenalin ( 2) and their ester derivatives 3-13 (see figure). the natural occurence of 6-o-isobutyryl-, 6-o-tigloyl-, 6-o-isovaleryl- and 6-o-(2-methyl)-butyrylhelenalin (compounds 9, 11, 12, 13) is reported for the first time. the qualitative sesquiterpene lactone composition in flowers of a. montana from different regions was found to be variable.198317405058
[arnica montana in facial injuries (proceedings)]. 2004855982
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