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open source 3d printable replacement parts for the who insecticide susceptibility bioassay system.malaria vector control and research rely heavily on monitoring mosquito populations for the development of resistance to public health insecticides. one standard method for determining resistance in adult mosquito populations is the world health organization test (who bioassay). the who bioassay kit consists of several acrylic pieces that are assembled into a unit. parts of the kit commonly break, reducing the capacity of insectaries to carry out resistance profiling. since there is at present o ...201931727146
evaluation of an alpha-cypermethrin + pbo mixture long-lasting insecticidal net veeralin® ln against pyrethroid resistant anopheles gambiae s.s.: an experimental hut trial in m'bé, central côte d'ivoire.long-lasting insecticidal nets (llins) are the primary method of malaria prevention. however, the widespread resistance to pyrethroids among major malaria vector species represents a significant threat to the continued efficacy of pyrethroid llin. piperonyl butoxide (pbo) is a synergist that inhibits the activity of metabolic enzymes of the cytochrome p450 family known to detoxify insecticides including pyrethroids. synergist llin incorporating pbo and a pyrethroid may provide improved control c ...201931730481
vectorial transmission of malaria in major districts of côte d'ivoire.to better understand the influence of periodic mass distribution of long-lasting insecticidal nets (llins) on malaria transmission, a 1-yr entomological survey was conducted in three major districts of côte d'ivoire. mosquitoes were sampled by human landing catches (hlc) in urban and rural areas of san pedro and abidjan (coastal), and in yamoussoukro (central). mosquitoes were identified morphologically and by molecular methods. the plasmodium falciparum circumsporozoite (csp) indices were measu ...201931785095
high insecticide resistance in the major malaria vector anopheles coluzzii in chad republic.the sahel region of chad republic is a prime candidate for malaria pre-elimination. to facilitate pre-elimination efforts in this region, two populations of anopheles coluzzii from central chad republic were characterized, their insecticide resistance profile and the possible molecular mechanisms driving the resistance in the field investigated.201931796068
experimental hut evaluation of dawaplus 3.0 ln and dawaplus 4.0 ln treated with deltamethrin and pbo against free-flying populations of anopheles gambiae s.l. in vallée du kou, burkina faso.in view of widespread pyrethroid resistance in malaria vectors in africa, two long-lasting insecticidal nets (llins) incorporated with a synergist, piperonyl butoxide (pbo), dawaplus 3.0 (deltamethrin + pbo in the roof panel; deltamethrin alone in the side panels) and dawaplus 4.0 (deltamethrin + pbo in all panels), were evaluated in an experimental hut trial in a rice growing irrigated area in burkina faso. efficacy of nets was tested against free-flying malaria vector, anopheles gambiae s.l., ...201931869350
transcontinental dispersal of anopheles gambiae occurred from west african origin via serial founder events.the mosquito anopheles gambiae s.s. is distributed across most of sub-saharan africa and is of major scientific and public health interest for being an african malaria vector. here we present population genomic analyses of 111 specimens sampled from west to east africa, including the first whole genome sequences from oceanic islands, the comoros. genetic distances between populations of a. gambiae are discordant with geographic distances but are consistent with a stepwise migration scenario in w ...201931886413
efficacy of actellic 300 cs-based indoor residual spraying on key entomological indicators of malaria transmission in alibori and donga, two regions of northern benin.the current study shows the results of three years of irs entomological monitoring (2016, before intervention; 2017 and 2018, after intervention) performed in alibori and donga, northern benin.201931888730
anopheline mosquito species composition, kdr mutation frequency, and parasite infectivity status in northern tanzania.the scaling-up of malaria control interventions in northern tanzania has resulted in a decline in malaria prevalence and vector species composition. despite this achievement, residual malaria transmission remains a concern in the area. the main aim of this study was to investigate malaria vector species composition, parasite infectivity rates, and the presence of insecticide knockdown resistance (kdr) mutations in three sites that have experienced a significant decline in malaria in northern tan ...202031923308
transcontinental dispersal of anopheles gambiae occurred from west african origin via serial founder events.the mosquito anopheles gambiae s.s. is distributed across most of sub-saharan africa and is of major scientific and public health interest for being an african malaria vector. here we present population genomic analyses of 111 specimens sampled from west to east africa, including the first whole genome sequences from oceanic islands, the comoros. genetic distances between populations of a. gambiae are discordant with geographic distances but are consistent with a stepwise migration scenario in w ...201931925292
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