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aqueous extract from hibiscus sabdariffa linnaeus ameliorate diabetic nephropathy via regulating oxidative status and akt/bad/14-3-3{gamma} in an experimental animal model.several studies point out that oxidative stress maybe a major culprit in diabetic nephropathy. aqueous extract of hibiscus sabdariffa l. (hse) has been demonstrated as having beneficial effects on anti-oxidation and lipid-lowering in experimental studies. this study aimed at investigating the effects of hibiscus sabdariffa l. on diabetic nephropathy in streptozotocin induced type 1 diabetic rats. our results show that hse is capable of reducing lipid peroxidation, increasing catalase and glutath ...200919965962
anti-inflammatory activities of extracts of thai spices and herbs with lipopolysaccharide-activated raw 264.7 murine macrophages.nitric oxide (no) and tumor necrosis factor-alpha (tnf-alpha) play important roles in inflammatory processes. this study examined whether 13 spices/herbs commonly used in thai dishes modulate the production of no and tnf-alpha by the raw 264.7 mouse macrophage cell line pretreated with plant extracts (1-100 microg/ml) prior to activation by bacterial lipopolysaccharide (lps). tested plant tissues were extracted with ethanol with the exception of roselle, which was extracted with 70% acetone. eig ...200920041774
traditional leafy vegetables in senegal: diversity and medicinal uses.six administrative regions of senegal were investigated. forty species of vegetable leaves which are traditionally consumed in senegal have been inventoried. all species are members of twenty-one families the most numerous of which are amaranthaceae juss., malvaceae juss., moraceae link., the papilionaceae giseke and tiliaceae juss. the species are subdivided into three groups: cultivated leafy vegetables, plants gathered annually, perennial sub-ligneous and ligneous species. the gathered specie ...200720161914
delayed puberty onset in rats that consumed aqueous extract of hibiscus sabdariffa during the juvenile-pubertal period.the report that intervention during the juvenile-pubertal period in rats modifies the phenotype induced by prenatal nutrition suggests some degree of plasticity in the juvenile-pubertal period. it is not known whether consumption of aqueous extract of hibiscus sabdariffa (hs) during the juvenile-pubertal period will affect the growth and onset of puberty in rats. the present study was therefore designed to investigate this. weaned 21-days-old rats, whose mothers were given food and water ad libi ...200920180327
therapeutic effects on murine oral candidiasis by oral administration of cassia (cinnamomum cassia) preparation.we examined the effects of spices and herbs on candida albicans growth using in vitro assay and therapeutic activity of some selected herbal preparations against murine oral candidiasis. all tested samples: lemongrass (cymbopogon citratus), lemon balm (melissa officinalis), thyme (thymus vulgaris), rosemary (rosmarinus officinalis), roselle (hibiscus sabdariffa), green tea (camellia sinensis), and cassia (cinnamomum cassia) inhibited candida mycelial growth in vitro. the results of this assay sh ...201020185867
effect of ethnomedicinal plants used in folklore medicine in jordan as antibiotic resistant inhibitors on escherichia coli.escherichia coli occurs naturally in the human gut; however, certain strains that can cause infections, are becoming resistant to antibiotics. multidrug-resistant e. coli that produce extended-spectrum beta lactamases (esbls), such as the ctx-m enzymes, have emerged within the community setting as an important cause of urinary tract infections (utis) and bloodstream infections may be associated with these community-onsets. this is the first report testing the antibiotic resistance-modifying acti ...201020187978
aqueous extract of hibiscus sabdariffa l. decelerates acetaminophen-induced acute liver damage by reducing cell death and oxidative stress in mouse experimental models.acetaminophen (aap)-induced oxidative stress can cause cell death to induce liver damage. the antioxidant effect of hibiscus sabdariffa l. (hs) was shown in previous studies. in this study the effect of hs extract (hse) on aap-induced liver injury in balb/c mice was investigated.201020355050
production of maize-bambara groundnut complementary foods fortified pre-fermentation with processed foods rich in calcium, iron, zinc and provitamin a.maize-bambara groundnut complementary foods are deficient in calcium, iron, zinc and vitamin a. food-to-food fortification could be cheaper, safer and more easily adopted by local communities compared to the use of chemically pure compounds and vitamins to enrich such foods.201020355082
hypolipidemic effect of ethanolic extract from the leaves of hibiscus sabdariffa l. in hyperlipidemic rats.the present study is designed to investigate the hypolipidemic effect of ethanolic extract from the leaves of hibiscus sabdariffa l. (hsee) in hyperlipidemic rats. in the present work, hsee was evaluated at three doses (i.e. 100, 200 and 300 mg/kg, orally) in cholesterol-induced (2 g/kg, orally) hyperlipidemic wistar rats. atorvastatin (10 mg/kg, orally) was used as the standard drug. administration of hsee (200 mg/kg and 300 mg/kg) together with continuous cholesterol feeding for four weeks sho ...201020369795
inhibitory effect of marinades with hibiscus extract on formation of heterocyclic aromatic amines and sensory quality of fried beef patties.heterocyclic aromatic amines (haa) are carcinogenic compounds found in the crust of fried meat. the objective was to examine the possibility of inhibiting haa formation in fried beef patties by using marinades with different concentrations of hibiscus extract (hibiscus sabdariffa) (0.2, 0.4, 0.6, 0.8 g/100g). after frying, patties were analyzed for 15 different haa by hplc-analysis. four haa meiqx (0.3-0.6 ng/g), phip (0.02-0.06 ng/g), co-mutagenic norharmane (0.4-0.7 ng/g), and harmane (0.8-1.1 ...201020418021
the effect of aqueous extracts of hibiscus sabdariffa (sorrel) calyces on heamatological profile and organ pathological changes in trypanasoma congolense - infected rats.the effects of aqueous extract of hibiscus sabdariffa calyces on haematology and pathological changes in some selected organs during experimental trypanosoma congolense infection of rats were investigated. three groups of rats were intraperitoneally infected with t. congolense (karu stock). one group was administered with the aqueous extract and another given a solution of vitamin c in drinking water; the remaining infected group was left untreated. data from these groups were compared with thos ...200920606781
potential mechanisms of hypocholesterolaemic effect of thai spices/dietary extracts.several thai spices/dietary ingredients were previously shown to have hypocholesterolaemic effects. these studies were mostly conducted in animal models in which the mechanisms of action were not yet well-established. therefore, this study aimed to investigate the potential mechanism of hypocholesterolaemic action of 12 selected plants, namely hibiscus sabdariffa l., moringa oleifera lam., cucurbita moschata duchesne, ananas comosus (l.) merr., zingiber officinale, morus alba l., camellia sinens ...201120623425
mechanism of delayed puberty in rats whose mothers consumed hibiscus sabdariffa during lactation.extract of the calyx of hibiscus sabdariffa linn. (hs) (malvaceae) has been reported to decrease fluid and food intake in lactating rats through a mechanism not yet fully understood. it has also been reported that rat pups undernourished during lactation have delayed puberty onset, suggesting a link between nutrition and onset of puberty. there is paucity of data addressing the effect of maternal consumption of hs during lactation on the onset of puberty in the female offspring.201020839905
effects of orthosiphon grandiflorus, hibiscus sabdariffa and phyllanthus amarus extracts on risk factors for urinary calcium oxalate stones in rats.we evaluated the antilithic effect of orthosiphon grandiflorus, hibiscus sabdariffa and phyllanthus amarus extracts on known risk factors for calcium oxalate stones in rats.201121075390
hepatoprotective and antioxidant effects of hibiscus sabdariffa extract against carbon tetrachloride-induced hepatocyte damage in cyprinus carpio.the present study aims to evaluate the hepatoprotective and antioxidant effects of hibiscus sabdariffa extract on the carbon tetrachloride (ccl(4))-induced hepatocyte damage in fish and provide evidence as to whether it can be potentially used as a medicine for liver diseases in aquaculture. h. sabdariffa extract (100, 200, and 400 μg/ml) was added to the carp primary hepatocyte culture before (pre-treatment), after (post-treatment), and both before and after (pre- and post-treatment) the incuba ...201121082285
[hibiscus sabdariffa l: source of antioxidant dietary fiber].dietary fiber and antioxidants are food constituents and functional ingredients that are generally addressed separately. nowadays there is scientific evidence that primary characteristics of df assigned to non starch polysaccharides and lignin (resistance to digestion and absorption in the small intestine and fermentation in the large intestine) can be extended to other indigestible food constituents that are resistant to digestion and absorption in the human small intestine with complete or par ...201021090279
chemopreventive properties and molecular mechanisms of the bioactive compounds in hibiscus sabdariffa linne.hibiscus sabdariffa linne is a traditional chinese rose tea and has been effectively used in folk medicines for treatment of hypertension, inflammatory conditions. h. sabdariffa aqueous extracts (hse) were prepared from the dried flowers of h. sabdariffa l., which are rich in phenolic acids, flavonoids and anthocyanins. in this review, we discuss the chemopreventive properties and possible mechanisms of various h. sabdariffa extracts. it has been demonstrated that hse, h. sabdariffa polyphenol-r ...201121291361
liposome-containing hibiscus sabdariffa calyx extract formulations with increased antioxidant activity, improved dermal penetration and reduced dermal toxicity.hibiscus sabdariffa linn, or roselle, is a medicinal plant used extensively in traditional thai medicine since ancient times. the extracts of roselle calyces possess antioxidant activity and have potential for development as active ingredients in cosmetic products. however the limitations of using roselle extracts in cosmetics are its low skin permeation and dermal irritation. liposome technology is an obvious approach that might overcome these problems. liposome formulations of standardized ros ...201021294418
antioxidant and drug detoxification potentials of hibiscus sabdariffa anthocyanin extract.the antioxidant and drug metabolizing potentials of hibiscus anthocyanin extract in ccl(4)- induced oxidative damage of rat liver was investigated. hibiscus anthocyanin extract effectively scavenge a-diphenyl-ß-picrylhydrazyl (dpph) radical, superoxide ion, and hydrogen peroxide. it produced a 92% scavenging effect of dpph radical at a concentration of 2.0 mg/ml. hibiscus anthocyanin extract produced a 69 and 90% scavenging effect on superoxide ion and hydrogen peroxide, respectively, at 1.0 mg/ ...201121314460
insecticide use and competition shape the genetic diversity of the aphid aphis gossypii in a cotton-growing landscape.field populations of the cotton aphid, aphis gossypii glover, are structured into geographically widespread host races. in the cotton-producing regions of west and central africa (wca), two genotypes have been repeatedly detected within the cotton host race, one of which (burk1) is prevalent (>90%) and resistant to several insecticides, as opposed to the second one (ivo). here, we conducted whole plant and field cage experiments to test hypotheses for such low genetic diversity, including select ...201121320362
herb-drug interaction between the extract of hibiscus sabdariffa l. and hydrochlorothiazide in experimental animals.abstract decoctions of hibiscus sabdariffa l. (family malvaceae) are very popular for the preparation of homemade refreshing drinks and are also used medicinally for a variety of ailments. particularly remarkable are the various scientific reports supporting diuretic and antihypertensive potentials. it is therefore not unusual for patients who are on orthodox antihypertensive medications to use medicinal h. sabdariffa drinks concomitantly without regard to the possibility of herb-drug interactio ...201121480802
characterization of natural fibers and their application in bone grafting substitutes.in the last decades, researchers have developed new materials to improve the quality of human life. owing to the frequent occurrence of bone fractures, it is important to develop plate materials for the fixation of fractured bones. these plate materials have to be lightweight, compatible with human tissues and ought to allow stiffness. natural fibers have the advantage that they are renewable resources and have marketing appeal. the asian markets have been supplying natural fibers for many years ...201121500767
determination of antimicrobial activity of sorrel (hibiscus sabdariffa) on esherichia coli o157:h7 isolated from food, veterinary, and clinical samples.abstract the use of medicinal plants as natural antimicrobial agents is gaining popularity. sorrel (hibiscus sabdariffa) is widely used for the treatment of diseases. the objective of this study was to investigate the antimicrobial activity of sorrel on escherichia coli o157:h7 isolates from food, veterinary, and clinical samples. phenolics of the calyces were extracted from 10 g of ground, freeze-dried samples using 100 ml of 80% aqueous methanol. concentrations of 10%, 5%, and 2.5% methanol ex ...201121548802
estimation of proximate composition, micronutrients and phytochemical compounds in traditional vegetables from andaman and nicobar islands.in present study, 10 preferred traditional vegetables from andaman and nicobar islands, india, were analysed for nutritional profiles. moisture content in their edible parts ranged from 83.43 to 94.78%. maximum ash content was recorded in portulaca oleracea, crude protein in colocasia esculenta, crude fibre in eryngium foetidum and fat in e. foetidum. phosphorus was maximum in ipomea aquatica, potassium in c. esculenta, zinc, calcium and manganese in centella asiatica, copper in sauropus androgy ...201121615278
antinociceptive, anti-inflammatory and antidiarrheal activities of ethanolic calyx extract of hibiscus sabdariffa linn. (malvaceae) in mice.to evaluate the antinociceptive, anti-inflammatory and antidiarrheal activities of the ethanolic calyx extract of hibiscus sabdariffa linn. in mice.201121669166
effect of extract of hibiscus on the ultrastructure of the testis in adult mice.hibiscus sabdariffa extract is a popular beverage in many tropical and sub-tropical countries. although, hibiscus tea is known for its medicinal effects for thousands of years, scientific evidence of its systemic safety is very limited. the current study aimed to assess the potential adverse effects of h. sabdariffa extract on sperm morphology and testicular ultrastructure of albino mice. thirty adult male albino mice were divided into three equal groups and were given: (a) distilled water, (b) ...201121798576
morphological characteristics and pathogenicity of fungi associated with roselle (hibiscus sabdariffa) diseases in penang, malaysia.roselle, or jamaica sorrel (hibiscus sabdariffa) is a popular vegetable in many tropical regions, cultivated for its leaves, seeds, stems and calyces which, the dried calyces are used to prepare tea, syrup, jams and jellies and as beverages. the main objectives of this study were to identify and characterise fungal pathogens associated with roselle diseases based on their morphological and cultural characteristics and to determine the pathogenicity of four fungi infecting roselle seedlings, name ...201121839160
Hibiscus sabdariffa polyphenolic extract inhibits hyperglycemia, hyperlipidemia, and glycation-oxidative stress while improving insulin resistance.H. sabdariffa polyphenolic extract (HPE) was demonstrated to inhibit high glucose-stimulated cellular changes. In this study, we analyzed the composition of HPE and used a type 2 diabetic rat model to test its protective effect. At least 18 phenolic compounds were found in HPE. Treatment with HPE reduced hyperglycemia and hyperinsulinemia, especially at the dose of 200 mg/kg. HPE decreased serum triacylglycerol, cholesterol, and the ratio of low density lipoprotein/high density lipoprotein (LDL/ ...201121870884
indigenous perception and characterization of yanyanku and ikpiru: two functional additives for the fermentation of african locust bean.indigenous perception, processing methods, and physicochemical and microbiological characteristics of yanyanku and ikpiru, two additives used to produce fermented african locust bean condiments, sonru and iru, were evaluated. according to producers, these additives accelerate the fermentation and soften the texture of the condiments. yanyanku is produced by spontaneous fermentation with either hibiscus sabdariffa or gossypium hirsutum or adansonia digitata seeds, whereas only hibiscus sabdariffa ...201121888591
the effect of hibiscus sabdariffa on lipid profile, creatinine, and serum electrolytes: a randomized clinical trial.background. hibiscus sabdariffa l. (hs), a member of malvaceae family, is a medicinal plant with a worldwide fame. its effect on reducing serum lipids is mentioned in several studies. the purpose of this study was to assess the efficacy of this plant in reducing the serum's lipids in hypertensive patients. materials and methods. ninety hypertensive patients were randomly assigned to receive hibiscus sabdariffa (hs) tea or black tea for 15 days. the patients were asked to drink the tea within 20 ...201121991538
Inhibition of calcium oxalate crystal deposition on kidneys of urolithiatic rats by Hibiscus sabdariffa L. extract.The present study aims at systematic evaluation of the calyces of Hibiscus sabdariffa to establish its scientific validity for anti-urolithiatic property using ethylene glycol-induced hyperoxaluria model in male albino rats. Administration of a mixture of 0.75% ethylene glycol and 2% ammonium chloride resulted in hyperoxaluria as well as increased renal excretion of calcium and phosphate. The decrease in the serum calcium concentration indicates an increased calcium oxalate formation. Supplement ...201122057204
anti-fungal activity of cold and hot water extracts of spices against fungal pathogens of roselle (hibiscus sabdariffa) in vitro.crude extracts of seven spices, viz. cardamom, chilli, coriander, onion, garlic, ginger, and galangale were made using cold water and hot water extraction and they were tested for their anti-fungal effects against the three roselle pathogens i.e. phoma exigua, fusarium nygamai and rhizoctonia solani using the 'poisoned food technique'. all seven spices studied showed significant anti-fungal activity at three concentrations (10, 20 and 30% of the crude extract) in-vitro. the cold water extract of ...201222138549
hibiscus sabdariffa extractivities on cadmium-mediated alterations of human u937 cell viability and activation.to investigate the effect of the anthocyanin-rich extract of hibiscus sabdariffa (h. sabdariffa) calyx on the viability of cadmium-treated u937 cells and cadmium-mediated activation of u937-derived macrophages.201222182640
evaluation of the potential of trichoderma viride in the control of fungal pathogens of roselle (hibiscus sabdariffa l.) in vitro.the potential of trichoderma viride as a bio-control agent was evaluated in vitro against roselle pathogens i.e. phoma exigua, fusarium nygamai and rhizoctonia solani[1] using the dual culture technique. volatile and non-volatile inhibitors of trichoderma were also evaluated for this purpose. t. viride[2] was shown to have a marked inhibitory effect on the tested pathogens in vitro. maximum inhibition occurred against p. exigua, with 71.76% reduction in mycelial radial growth. the three pathogen ...201222261114
adsorption and desorption properties of macroporous resins for anthocyanins from the calyx extract of roselle (hibiscus sabdariffa l.).adsorption of roselle anthocynins, a natural pigment, onto various macroporous resins was optimized to develop a simple and efficient process for industrial separation and purification of roselle anthocyanins. nine different macroporous resins (ab-8, x-5, hpd-100, sp-207, xad-4, ls-305a, dm-21, ls-610b, and ls-305) were evaluated for the adsorption properties of the anthocyanins extracted from the calyx extract of hibiscus sabdariffa l. the influences of phase contact time, solution ph, initial ...201222329796
predominant effects of host plant species on aphis gossypii aphid and e. pisyrphus balteatus hoverfly in a tritrophic approach.the aphid aphis gossypii glover (homoptera: aphididae) is known as worldwide important pest. it causes serious injuries to crops, but is also able to feed on various cultivated and wild plants. some programs are developped to control this aphid. in many studies, hoverfy episyrphus balteatus de geer (diptera: syrphidae) is used as an efficient and aphid specific predator in biological control systems. in this work, we study cotton aphid choice plant discrimination, the effect of host plants on it ...201122696952
hibiscus sabdariffa linnaeus (malvaceae), curcumin and resveratrol as alternative medicinal agents against metabolic syndrome.metabolic syndrome (ms) is an obesity-associated collection of disorders, each of which contributes to cardiovascular risk. for patients with ms, it is difficult to follow a diet/exercise regime that would improve their symptoms. therefore, the investigation of agents that may deal with its more serious aspects is an important medical field for research. numerous experimental studies have confirmed the important role of medicinal plants or their active components in the prevention and treatment, ...201322721439
in vitro inhibitory effects of plant-based foods and their combinations on intestinal α-glucosidase and pancreatic α-amylase.plant-based foods have been used in traditional health systems to treat diabetes mellitus. the successful prevention of the onset of diabetes consists in controlling postprandial hyperglycemia by the inhibition of α-glucosidase and pancreatic α-amylase activities, resulting in aggressive delay of carbohydrate digestion to absorbable monosaccharide. in this study, five plant-based foods were investigated for intestinal α-glucosidase and pancreatic α-amylase. the combined inhibitory effects of pla ...201222849553
ni speciation in tea infusions by monolithic chromatography--icp-ms and q-tof-ms.for humans, ni is not considered to be an essential trace element. its compounds, at levels present in foodstuffs and drinks, are generally considered to be safe for consumption, but for individuals who already suffer from contact allergy to ni and may be subject to develop systemic reactions from its dietary ingestion, dietary exposure to ni must be kept under control. being the second most popular beverage, tea is a potential source of dietary ni. present knowledge on its speciation in tea inf ...201323232960
co-production of surfactin and a novel bacteriocin by bacillus subtilis subsp. subtilis h4 isolated from bikalga, an african alkaline hibiscus sabdariffa seed fermented condiment.bikalga is a hibiscus sabdariffa seed fermented condiment widely consumed in burkina faso and neighboring countries. the fermentation is dominated by bacillus subtilis group species. ten b. subtilis subsp. subtilis (six isolates) and bacillus licheniformis (four isolates) isolated from traditional bikalga were examined for their antimicrobial activity against a panel of 36 indicator organisms including gram-positive and gram-negative bacteria and yeasts. the bacillus spp. isolates showed variabl ...201323466466
aluminium and other elements in selected herbal tea plant species and their infusions.the determination of al, b, cu, fe, mn, ni, p, zn and ca, k, mg by inductively coupled plasma optical emission spectrometry (icp-oes) and flame atomic absorption spectroscopy (faas), respectively, in digests and infusions of hibiscus sabdariffa (petals), rosa canina (receptacles), ginkgo biloba (leaves), cymbopogon citratus (leaves), aloe vera (leaves) and panax ginseng (roots) was carried out in this study. particular attention has been given to al and heavy metals for the identification of pos ...201323561167
bacillus amyloliquefaciens ssp. plantarum strains as potential protective starter cultures for the production of bikalga, an alkaline fermented food.to identify and screen dominant bacillus spp. strains isolated from bikalga, fermented seeds of hibiscus sabdariffa for their antimicrobial activities in brain heart infusion (bhi) medium and in a h. sabdariffa seed-based medium. further, to characterize the antimicrobial substances produced.201323565829
biodiversity of aerobic endospore-forming bacterial species occurring in yanyanku and ikpiru, fermented seeds of hibiscus sabdariffa used to produce food condiments in benin.yanyanku and ikpiru made by the fermentation of malcavene bean (hibiscus sabdariffa) are used as functional additives for parkia biglobosa seed fermentations in benin. a total of 355 aerobic endospore-forming bacteria (aefb) isolated from yanyanku and ikpiru produced in northern and southern benin were identified using phenotypic and genotypic methods, including gtg5-pcr, m13-pcr, 16s rrna, gyra and gyrb gene sequencing. generally, the same 5-6 species of the genus bacillus predominated: bacillu ...201323571124
nutritional composition of minor indigenous fruits: cheapest nutritional source for the rural people of bangladesh.in line of the development of a food composition database for bangladesh, 10 minor indigenous fruits were analysed for their nutrient composition comprising ascorbic acid, carotenoids and mineral values. nutrient data obtained have been compared with published data reported in different literatures, book and united states department of agriculture-national nutrient database for standard reference. ascorbic acid was highest in wood apple and lowest in roselle. monkey jack contained the highest am ...201223601393
new experimental hosts of tobacco streak virus and absence of true seed transmission in leguminous hosts.of 70 plant species tested, 50 species were susceptible to tobacco streak virus (tsv) on sap inoculation. both localized (necrotic and chlorotic spots) and systemic (necrotic spots, axillary shoot proliferation, stunting, total necrosis and wilt) symptoms are observed by majority of plant species. eleven new experimental hosts were identified viz., amaranthus blitum var. oleracea (chaulai sag), celosia cristata (cocks comb), beta vulgaris var. bengalensis (palak/indian spinach), calendula offici ...201123637490
physicochemical properties and antimicrobial activity of roselle (hibiscus sabdariffa l.).the therapeutic action of a plant depends on its chemical constituents. in this study, experiments were carried out in order to evaluate the effect of extraction conditions on the antioxidative and antimicrobial activities of roselle (hibiscus sabdariffa l.).201323749748
wound healing potential of formulated extract from hibiscus sabdariffa calyx.wound healing agents support the natural healing process, reduce trauma and likelihood of secondary infections and hasten wound closure. the wound healing activities of water in oil cream of the methanol extract of hibiscus sabdariffa l. (malvaceae) was evaluated in rats with superficial skin excision wounds. antibacterial activities against pseudomonas aeroginosa, staphylococcus aureus and echerichia coli were determined. the total flavonoid content, antioxidant properties and thin layer chroma ...201323901160
by-product from decoction process of hibiscus sabdariffa l calyces as a source of polyphenols and dietary fiber.dietary fiber and antioxidant compounds are widely used as functional ingredients. the market in this field is competitive and the search of new types and quality ingredients for the food industry is on rise. the aim of this study was to evaluate the composition and antioxidant activity in by-products generated during decoction process of four mexican hibiscus sabdariffa l. calyces cultivars ('criolla', 'china', 'rosalis' and 'tecoanapa') in order to consider as a source of functional ingredient ...201323913523
effects of hibiscus sabdariffa l. on serum lipids: a systematic review and meta-analysis.prevention of cardiovascular disease by modifying its major risk factors, including serum cholesterol levels, is an important strategy. hibiscus sabdariffa l. has been promoted for reducing cholesterol levels, but its reported impact on cholesterol levels has been inconsistent. the study aimed to assess systematically the evidence and quality of current research on the effect of hibiscus sabdariffa l. on blood lipids and its adverse effects.201324120746
effects of consuming diets containing agave tequilana dietary fibre and jamaica calyces on body weight gain and redox status in hypercholesterolemic rats.dietary fibre (df) obtained from agave tequilana, which is rich in fructans and insoluble df, and jamaica calyces (hibiscus sabdariffa), which is rich in df and phenolic compounds, were assessed as new potential functional ingredients using the hypercholesterolemic animal model. wistar rats (200-250 g) were divided into 3 groups (n=8) and fed with cholesterol-rich diets supplemented with cellulose (cc, control), agave df (adf) or adf with jamaica calyces (adf-jc). after consuming the test diets ...201424262526
antimicrobial activity of hibiscus sabdariffa aqueous extracts against escherichia coli o157:h7 and staphylococcus aureus in a microbiological medium and milk of various fat concentrations.hibiscus sabdariffa l. calyces are widely used in the preparation of beverages. the calyces contain compounds that exhibit antimicrobial activity, yet little research has been conducted on their possible use in food systems as antimicrobials. aqueous extracts prepared from the brand "mi costenita" were sterilized by membrane filtration (0.22-μm pore size) or autoclaving (121 °c, 30 min) and tested for antimicrobial activity against the foodborne pathogens escherichia coli o157:h7 strains atcc 43 ...201424490920
occurrence of root rot and vascular wilt diseases in roselle (hibiscus sabdariffa l.) in upper egypt.roselle (hibiscus sabdariffa l.) family malvaceae is an important crop used in food, cosmetics and pharmaceutics industries. roselle is cultivated mainly in upper egypt (qena and aswan governorates) producing 94% of total production. root rot disease of roselle is one of the most important diseases that attack both seedlings and adult plants causing serious losses in crop productivity and quality. the main objective of the present study is to identify and characterize pathogens associated with r ...201424808737
ethno-medicinal knowledge and plants traditionally used to treat anemia in tanzania: a cross sectional survey. 201424835027
ethnobotanical study of indigenous knowledge on medicinal and nutritious plants used to manage opportunistic infections associated with hiv/aids in western uganda.traditional medicine plays an important role in the daily lives of the people of uganda to treat a wide range of health problems. our study presents results of an ethnobotanical inventory conducted to identify and document medicinal and nutritional plants used in the management of opportunistic infections associated with human immunodeficiency virus / acquired immunodeficiency syndrome (hiv/aids), the plant parts used, preparation and administration methods of herbal remedies.201424862490
evaluation of the potential nephroprotective and antimicrobial effect of camellia sinensis leaves versus hibiscus sabdariffa (in vivo and in vitro studies).green tea and hibiscus are widely consumed as traditional beverages in yemen and some regional countries. they are relatively cheap and the belief is that they improve health state and cure many diseases. the aim of this study was to evaluate the potential protective and antibacterial activity of these two famous plants in vitro through measuring their antibacterial activity and in vivo through measuring nonenzymatic kidney markers dysfunction after induction of nephrotoxicity by gentamicin. gra ...201424949007
hibiscus sabdariffa extract inhibits in vitro biofilm formation capacity of candida albicans isolated from recurrent urinary tract infections.to explore the prevention of recurrent candiduria using natural based approaches and to study the antimicrobial effect of hibiscus sabdariffa (h. sabdariffa) extract and the biofilm forming capacity of candida albicans strains in the present of the h. sabdariffa extract.201425182280
levels of some microelements and essential heavy metals in herbal teas in serbia.levels of fe, mn, cu, zn, mo, co, ni, se, sn and al were determined in 14 medicinal plants from serbia, which are widely used in phytopharmacy as herbal teas. the following plants were investigated: yarrow (achillea millefolium l.), basil (ocimum hasilicum l.), st. john's wort (hypericum perforatum l.), peppermint (mentha x piperita l.), field horsetail (equisetum arvense l.), stinging nettle (urtica dioica l.), thyme (thymus serpyllum l.), maize silk (zea mays l. - maydis stigma), hibiscus (hib ...201425265817
processing effects on the antioxidant activities of beverage blends developed from cyperus esculentus, hibiscus sabdariffa, and moringa oleifera extracts.the discovery of bioactive compounds in foods has changed the dietary lifestyle of many people. cyperus esculentus (tigernut) is highly underutilized in africa, yet tigernut extract is highly profitable in europe. this study aims to add value to tigernut extract by revealing its health benefits and food value. in this study, tigernut tubers were germinated or roasted and the extracts were combined with moringa oleifera extract (moe) or hibiscus sabdariffa extract (hse) and spiced with ginger to ...201425320721
control of root rot and wilt diseases of roselle under field conditions.roselle (hibiscus sabdariffa l.) is one of the most important medicinal crops in many parts of the world. in this study, the effects of microelements, antioxidants, and bioagents on fusarium oxysporum, f. solani, and macrophomina phaseolina, the causal pathogens of root rot and wilt diseases in roselle, were examined under field conditions. preliminary studies were carried out in vitro in order to select the most effective members to be used in field control trials. our results showed that micro ...201425606010
phenolic compounds of hibiscus sabdariffa and influence of organic residues on its antioxidant and antitumoral properties.the aim of this study was to evaluate the phenolic and flavonoids contents and the antioxidant and antitumoral activity of leaf and calyx methanolic extracts from hibiscus sabdariffa (roselle) cultivated with poultry litter and organosuper® under three modes of application. the total phenolic content in the each extract was determined using the folin-ciocalteu reagent and for aluminium chloride flavonoids. the antioxidant parameters were analyzed using a 2, 2-diphenyl-1-picrylhydrazyl (dpph.) fr ...201525945622
aqueous extracts of hibiscus sabdariffa calyces decrease hepatitis a virus and human norovirus surrogate titers.hibiscus sabdariffa extract is known to have antioxidant, anti-diabetic, and antimicrobial properties. however, their effects against foodborne viruses are currently unknown. the objective of this study was to determine the antiviral effects of aqueous extracts of h. sabdariffa against human norovirus surrogates (feline calicivirus (fcv-f9) and murine norovirus (mnv-1)) and hepatitis a virus (hav) at 37 °c over 24 h. individual viruses (~5 log pfu/ml) were incubated with 40 or 100 mg/ml of aqueo ...201526143492
cardiac and vascular synergic protective effect of olea europea l. leaves and hibiscus sabdariffa l. flower extracts.this study was aimed at investigating the cardiovascular effects of an olea europea l. leaf extract (oee), of a hibiscus sabdariffa l. flower extract (hse), and of their 13 : 2 w/w mixture in order to assess their cardiac and vascular activity. both extracts were fully characterized in their bioactive compounds by hplc-ms/ms analysis. the study was performed using primary vascular endothelial cells (huvecs) to investigate the antioxidant and cytoprotective effect of the extracts and their mixtur ...201526180582
herbal extracts in oral health care - a review of the current scenario and its future needs.oral diseases are among the major public health problems and the commonest of chronic diseases that affect mankind. the application of natural products for the control of oral diseases is considered as an interesting alternative to synthetic antimicrobials due to their lower negative impact, and for the effort to overcome primary or secondary resistance to the drug during therapy.201726392704
a review of commercially important african medicinal plants.data on the relative importance and research status of commercially relevant african medicinal plants are needed for developing new research strategies in order to stimulate much-needed ethnopharmacological research and to promote the commercialization of african plants.201526498493
a systematic review of medicinal plants used for weight loss in brazil: is there potential for obesity treatment?obesity is a pandemic disease and its prevalence is still increasing. moreover, it has important costs to public health. in brazil, many plants are used for weight loss by overweight or obese people, but there is a lack of scientific basis for this practice. many ethnobotanical studies aiming to characterize this usage have been published, but they are still limited by the region considered and the diversity of the popular knowledge.201526520790
fourier transform infrared spectroscopy (ftir) analysis, chlorophyll content and antioxidant properties of native and defatted foliage of green leafy vegetables.ftir analysis for five selected green leafy vegetables (glvs) viz., hibiscus cannabinus l., (kenaf), h. sabdariffa l., (roselle), basella alba l., (vine spinach), b. rubra l. (malabar spinach) and rumex vesicarius l., (sorrel) confirmed the presence of free alcohol, intermolecular bonded alcohol, intramolecular bonded alcohol, alkane, aromatic compounds, imine or oxime or ketone or alkene, phenol and amine stretching. the chlorophyll content was higher in native leaves of b. alba (2.96 g/kg) tha ...201526604386
local food-based complementary feeding recommendations developed by the linear programming approach to improve the intake of problem nutrients among 12-23-month-old myanmar children.poor feeding practices result in inadequate nutrient intakes in young children in developing countries. to improve practices, local food-based complementary feeding recommendations (cfr) are needed. this cross-sectional survey aimed to describe current food consumption patterns of 12-23-month-old myanmar children (n 106) from ayeyarwady region in order to identify nutrient requirements that are difficult to achieve using local foods and to formulate affordable and realistic cfr to improve dietar ...201626696232
vortex- and co2 -gas-assisted liquid-liquid microextraction with salt addition for the high-performance liquid chromatographic determination of furanic compounds in concentrated juices and dried fruits.a novel microextraction method based on vortex- and co2 -assisted liquid-liquid microextraction with salt addition for the isolation of furanic compounds (5-hydroxymethyl-2-furaldehyde, 5-methyl-2-furaldehyde, 2-furaldehyde, 3-furaldehyde, 2-furoic and 3-furoic acids) was developed. purging the sample with co2 was applied after vortexing to enhance the phase separation and mass transfer of the analytes. the optimum extraction conditions were: extraction solvent (volume), propyl acetate (125 μl); ...201626718308
in vitro synergistic effect of hibiscus sabdariffa aqueous extract in combination with standard antibiotics against helicobacter pylori clinical isolates.context the increasing problem of drug-resistant strains has led to the failure of current treatment regimens of helicobacter pylori (hp) infection. recently, a new treatment strategy has been developed to overcome the problem by using natural products in combination with antibiotics to enhance the treatment efficacy. objective the antimicrobial combinatory effect of the aqueous extract of hibiscus sabdariffa l. (malvaceae) (aehs) with antibiotics (clarithromycin, cla; amoxicillin, amx; metronid ...201626731378
plants with potential use on obesity and its complications.obesity is the most prevalent nutritional disease and a growing public health problem worldwide. this disease is a causal component of the metabolic syndrome related with abnormalities, including hyperglycemia, dyslipidemia, hypertension, inflammation, among others. there are anti-obesity drugs, affecting the fundamental processes of the weight regulation; however they have shown serious side effects, which outweigh their beneficial effects. most recent studies on the treatment of obesity and it ...201526869866
aqueous extracts of hibiscus sabdariffa calyces to control aichi virus.aqueous hibiscus sabdariffa extracts possess antimicrobial properties with limited information available on their antiviral effects. aichi virus (aiv) is an emerging foodborne pathogen that causes gastroenteritis. vaccines are currently unavailable to prevent their disease transmission. the objective of this study was to determine the antiviral effects of aqueous h. sabdariffa extracts against aiv. aiv at ~5 log pfu/ml was incubated with undiluted (200 mg/ml), 1:1 (100 mg/ml) or 1:5 (40 mg/ml) d ...201626892338
effect of roselle calyx extract on in vitro viability and biofilm formation ability of oral pathogenic bacteria.to investigate the effect of the roselle calyx extract (rce) (hibiscus sabdariffa l.) on the in vitro viability and biofilm formation ability of oral pathogenic bacteria.201626919939
investigation of free amino acid, total phenolics, antioxidant activity and purine alkaloids to assess the health properties of non-camellia tea.to find novel functional beverages from folk teas, 33 species of frequently used non-camellia tea (plants other than camellia) were collected and compared with camellia tea (green tea, pu-erh tea and black tea) for the first time. data are reported here on the quantities of 20 free amino acids (faas) and three purine alkaloids (measured by uhplc), total polyphenols (measured by folin-ciocalteu assay), and antioxidant activity (dpph). the total amounts of faas in non-camellia tea (0.62-18.99 mg/g ...201627006902
hibiscus sabdariffa l. flowers and olea europea l. leaves extract-based formulation for hypertension care: in vitro efficacy and toxicological profile.olea europaea l. leaves extract (oe) and hybiscus sabdariffa l. flowers extract (hs) have calcium antagonistic properties. aim of this work was to study the cardiovascular effects of pres phytum(®), a nutraceutical formulation containing a mixture of the two extracts and the excipients, and investigate its possible off-target effects, using in vitro biological assays on guinea pig isolated organs. cardiovascular effects were assessed using guinea pig atria and aorta. the effects of pres phytum o ...201627152980
transition rates of selected metals determined in various types of teas (camellia sinensis l. kuntze) and herbal/fruit infusions.teas and raw materials used as ingredients of herbal and fruit infusions (hfi) were analysed by means of icp-ms for their content of aluminium, arsenic, cadmium, copper, lead and mercury in the dry product and in the infusion. samples of tea (camellia sinensis l. kuntze) were selected to include different origins, types (black, green), leaf grades (whole leaf, broken, fannings, dust) and manufacturing techniques (orthodox, "crush, tear, curl"). the selected hfi raw materials (chamomile, elderber ...201727542446
development of functional beverages from blends of hibiscus sabdariffa extract and selected fruit juices for optimal antioxidant properties.the demand for functional foods and drinks with health benefit is on the increase. the synergistic effect from mixing two or more of such drinks cannot be overemphasized. this study was carried out to formulate and investigate the effects of blends of two or more of pineapple, orange juices, carrot, and hibiscus sabdariffa extracts (hse) on the antioxidant properties of the juice formulations in order to obtain a combination with optimal antioxidant properties. experimental design was carried ou ...201627625770
triple bag hermetic technology for controlling a bruchid (spermophagus sp.) (coleoptera, chrysomelidae) in stored hibiscus sabdariffa grain.we assessed the performance of hermetic triple layer purdue improved crop storage (pics) bags for protecting hibiscus sabdariffa grain against storage insects. the major storage pest in the grain was a bruchid, spermophagus sp.. when we stored infested h. sabdariffa grain for six months in the woven polypropylene bags typically used by farmers, the spermophagus population increased 33-fold over that initially present. the mean number of emergence holes per 100 seeds increased from 3.3 holes to 3 ...201627990030
attachment of 13 types of foodborne bacteria to jalapeño and serrano peppers and antibacterial effect of roselle calyx extracts, sodium hypochlorite, colloidal silver, and acetic acid against these foodborne bacteria on peppers.chili peppers are a very important crop in mexico. however, these peppers have been associated with salmonella infection outbreaks in the united states, and salmonella and diarrheagenic escherichia coli pathotypes have been isolated from jalapeño and serrano peppers in mexico. to decrease microbial contamination of fruits and vegetables, chemical agents are commonly used; however, chemical agents used to eliminate pathogenic bacteria on vegetables have a limited antimicrobial effect. roselle ( h ...201728199144
recurrent urinary tract infections in women: risk factors, etiology, pathogenesis and prophylaxis.urinary tract infections (utis) are one of the most common bacterial infections in women, often as a recurrent disease. uropathogenic escherichia coli (upec) is the most common pathotype of extraintestinal pathogenic e. coli (expec) found among patients with uti. the human intestinal can act as a reservoir of upec, with the female urethra being infected by fecal material containing upec. adhesion of bacteria to the epithelial cells of urogenital mucosa is an important mechanism in the pathogenes ...201728262045
combination effect of antituberculosis drugs and ethanolic extract of selected medicinal plants against multi-drug resistant mycobacterium tuberculosis isolates.adverse drug reaction and resistance to antituberculosis drugs remain the causes of tuberculosis therapeutic failure. this research aimed to find the combination effect of standard antituberculosis drugs with hibiscus sabdariffa l., kaempferia galanga l., and piper crocatum n.e. br against multi-drug resistant (mdr) mycobacterium tuberculosis isolates. two mdr strains (i.e., isoniazid/ethambutol resistant and rifampicin/streptomycin resistant) of m. tuberculosis were inoculated in löwenstein-jen ...201728335544
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