Publications

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lethal mutations and balanced lethal systems in aspergillus nidulans. 19676064441
chromosome instability related to gene suppression in aspergillus nidulans. 19676064104
a revised map of the eight linkage groups of aspergillus nidulans. 19676061654
synchrony of nuclear replication in individual hyphae of aspergillus nidulans.the synchrony of nuclear replication in individual, multinucleate hyphae of aspergillus nidulans has been investigated. samples were taken from cultures of germinating conidiospores, and the relative frequency of hyphae containing two to eight nuclei was determined. because the conidiospores are mononucleate, complete synchrony will yield populations of hyphae containing only 2(n) nuclei, n being the number of doublings after germination. the appearance of hyphae with total numbers of nuclei oth ...19676057801
a system for the study of interlocus specificity for both forward and reverse mutation in at least eight gene loci in aspergillus nidulans. 19676054957
regulation of nitrate reduction in aspergillus nidulans. 19676052720
kinetic studies of the induction of nitrate reductase and cytochrome c reductase in the fungus aspergillus nidulans.in an earlier paper (cove, 1966) it was reported that the kinetics of appearance of nitrate reductase (nadph-nitrate oxidoreductase, ec 1.6.6.3) on the addition of nitrate to a growing culture of aspergillus nidulans were different in certain respects from those found for many escherichia coli enzymes. when urea is used as an initial nitrogen source, a further difference is found: enzyme synthesis is no longer continuous. this interruption of synthesis does not appear to be due to synchronous ce ...19676049855
inhibition of the lysis of fungi by melanins.evidence is presented that the resistance of aspergillus nidulans hyphae to lysis by a beta-(1-->3) glucanase-chitinase mixture results from the presence of melanin in the fungal walls. the resistance of the walls to digestion was directly correlated with the melanin content of the mycelium. a melanin-less mutant of a. nidulans was highly susceptible to hydrolysis by the enzyme mixture. preincubation of a synthetic melanin with the glucanase, chitinase, and a protease, before addition of the sub ...19676035264
genetic and cytoplasmic control of undifferentiated growth in aspergillus nidulans. 19676034180
the mechanism of action of proline suppressors in aspergillus nidulans. 19676034041
purification of two alkaline phosphatases from aspergillus nidulans. 19676030350
enzyme analysis of the tryptophan pathway in aspergillus nidulans. 19676029970
complementation analysis of the tryptophan pathway in aspergillus nidulans. 19676029969
use of analogues and the substrate-sensitivity of mutants in analysis of purine uptake and breakdown in aspergillus nidulans.aspergillus mutants resistant to various purine analogues (purine, 8-azaguanine, 2-thioxanthine, and 2-thiouric acid) are defective in at least one step of purine uptake or breakdown. the properties of these mutants show that there are two uptake systems for purines, one which mediates the uptake of hypoxanthine, guanine, and adenine, and the other, xanthine and uric acid. allantoinase-less strains are sensitive to the toxic effects of allantoin accumulation. they are severely inhibited when gro ...19676025432
electron transport pathways in riboflavinless mutants of aspergillus nidulans. 19666005316
fine analysis of mitotic intracistronic crossing-over in aspergillus nidulans. 19666004996
fine structure analysis of the gene for p-fluoro-phenylalanine resistance in aspergillus nidulans. 19666004989
a pair of pteridine derivatives in a heterokaryon of two mutants of aspergillus nidulans. 19665987145
formation of 4,5-diaminouracil in a riboflavineless mutant of aspergillus nidulans. 19665987043
genetical analysis of proline mutants and their suppressors in aspergillus nidulans. 19665980118
the influence of the cytoplasm on mutation in aspergillus nidulans. 19665972693
isolation of 5-amino-4-ribitylaminouracil from a riboflavineless mutant of aspergillus nidulans. 19665971789
interlocus specificity for chemical mutagens in aspergillus nidulans. 19665964558
thin-layer chromatographic separation of the metabolic products of aspergillus nidulans. 19665958835
kinetics of fungal growth and phosphatase formation in aspergillus nidulans.dorn, g. (albert einstein college of medicine, new york, n.y.), and w. rivera. kinetics of fungal growth and phosphatase formation in aspergillus nidulans. j. bacteriol. 92:1618-1622. 1966.-a liquid culture system is described for growing aspergillus nidulans in a manner amenable to kinetic studies. changes in dry weight, protein, deoxyribonucleic acid (dna), inorganic phosphate, alkaline phosphatase, and acid phosphatase activity were followed over a 40-hr interval. in both limiting- and high-p ...19665958101
the induction and repression of nitrate reductase in the fungus aspergillus nidulans. 19665940632
studies on the inhibition and mutation of aspergillus nidulans by acridines. 19665931141
analysis of induced mutations in aspergillus nidulans. i. uv- and hno2-induced mutations. 19665929395
recessive mutants at unlinked loci which complement in diploids but not in heterokaryons of aspergillus nidulans. 19665929247
somatically unstable mutants of aspergillus nidulans. 19665925191
observations on the effects of a chromosome duplication in aspergillus nidulans. 19665915374
isolation of 6,7-dimethyl-8-ribityl lumazine from a riboflavin-less mutant of aspergillus nidulans. 19665915130
complementation at the adenylosuccinase locus in aspergillus nidulans. 19655882197
an investigation of the suitability of the suppressors of meth 1 in aspergillus nidulans for the study of induced and spontaneous mutation. 19655878248
polarized negative interference in the lys-51 region of aspergillus nidulans. 19655872613
resistance to various inhibitors in aspergillus nidulans. 19655867759
purification of nitrate reductase and cytochrome c reductase from aspergillus nidulans. 19655866385
wild-type and mutant stocks of aspergillus nidulans. 19655857598
origins of translocations in aspergillus nidulans. 19655857597
phosphatase mutants in aspergillus nidulans.three mutants at three different phosphatase loci produce inactive enzymes at 35 degrees c but partially or fully active enzynmes at 25 degrees c. furthermore, a suppressor mutant (su5pala1) which restores alkaline phosphatase activity in the pala1 mtutant is an allele of palcc4, a mzutant with a simultaneous reduction in alkaline and acid phosphatase activity. these data suggest that the phosphataseproteins may be made up of two or more different polypeptide chains, and that some of the polypep ...19655852975
the use of p-fluorophenylalanine with 'master strains' of aspergillus nidulans for assigning genes to linkage groups. 19655848714
the two-way selection of mutants and revertants in respect of acetate utilization and resistance to fluoro-acetate in aspergillus nidulans. 19655848711
isolation and inhibitory effects of kb cell cultures of 3'-deoxyandenosine from aspergillus nidulans (eidam) wint. 19645836540
a kinetic study of the growth of aspergillus nidulans and other fungi. 19695822157
melanin production in aspergillus nidulans. 19695810076
uv-sensitive mutants increasing mitotic crossing-over in aspergillus nidulans. 19695807344
organization of enzymes in the common aromatic synthetic pathway: evidence for aggregation in fungi.centrifugation in sucrose density gradients of partially purified extracts from six species of fungi, i.e., rhizopus stolonifer, phycomyces nitens, absidia glauca (phycomycetes), aspergillus nidulans (ascomycetes), coprinus lagopus, and ustilago maydis (basidiomycetes), indicate that the five enzymes catalyzing steps two to six in the prechorismic acid part of the polyaromatic synthetic pathway sediment together. the sedimentation coefficients for these enzymes are very similar in the six specie ...19695802608
permeability properties of aspergillus nidulans protoplasts.the regeneration of mycelial forms from protoplasts of mutant and wild-type strains of aspergillus nidulans was followed microscopically under conditions with which the rate of regeneration depends upon a specific transport function. this method has shown that at least four uptake systems-one for divalent anions, two for purines, and one for sugars-remain functional after removal of the cell wall.19695802597
reversion of non-nitrate utilizing (nia d) mutants of aspergillus nidulans. 19695796514
methylammonium resistance in aspergillus nidulans.mutants of aspergillus nidulans resistant to methylammonium toxicity are simultaneously derepressed in the presence of ammonium for apparently all ammonium-repressible activities. enzyme assays directly demonstrate derepression of nitrate, nitrite, and hydroxylamine reductases, xanthine dehydrogenase, urate oxidase, and allantoinase, whereas in vivo tests show that ammonium and methylammonium repression or inhibition (or both) is relieved in these mutants in pathways of nitrate assimilation, pur ...19695788705
autoregulation of the synthesis of nitrate reductase in aspergillus nidulans.in aspergillus nidulans, the syntheses of nitrate and nitrite reductases are induced by nitrate, and are repressed by ammonium. it is possible in wild-type strains to overcome partially the repressive effect of ammonium, by the addition of high concentrations of nitrate to the growth medium. mutations which lead to the production of abnormal nitrate reductase affect in addition the control of the synthesis of the nitrate-metabolizing enzymes, which in these strains are produced constitutively. t ...19695776531
mutants of the arginine-proline pathway in aspergillus nidulans. 19695764741
cell volume per nucleus in haploid and diploid strains of aspergillus nidulans. 19695764740
[aspergillus nidulans, agent of mycetoma]. 19685756586
sexual and asexual phases of aspergillus nidulans in an egret. 19685750671
influence of chromosomal aberrations on meiotic and mitotic nondisjunction in aspergillus nidulans. 19685732416
[recent contribution to the study of mycetoma in senegal. neotestudina rosatii. pyrenochaeta romeroi. aspergillus nidulans]. 19685713774
nonrandom sister chromatid segregation and nuclear migration in hyphae of aspergillus nidulans.radioactive conidiospores of aspergillus nidulans were prepared by growing a purine-requiring mutant with tritiated adenine. when these spores germinated in a nonradioactive medium, the dispersion of the original chromosome set could be followed by treating the hyphae with ribonuclease and preparing radioautograms. germinating spores with four or eight nuclei contained two highly labeled nuclei and two or six nuclei with much less or no radioactivity. successive mitotic divisions thus distribute ...19685685997
the nature of mitotic intragenic recombination in aspergillus nidulans. 19685685164
metabolic changes in biotin-deficient aspergillus nidulans. 19685684683
evidence for an alternative pathway of xanthine oxidation in aspergillus nidulans. 19685680611
the induction and repression of the enzymes of purine breakdown in aspergillus nidulans. 19685680610
glucose metabolism in aspergillus nidulans. 19685677993
induced mutation in uv-sensitive mutants of aspergillus nidulans and neurospora crassa. 19685672966
genetic analysis of the first steps of sulphate metabolism in aspergillus nidulans. 19685671427
regulation and timing of deoxyribonucleic acid synthesis in hyphae of aspergillus nidulans.pulse labeling of deoxyribonucleic acid (dna) and radioautography have been used to study the effect of growth rate on nuclear replication in aspergillus nidulans. when conidia were germinated in media supporting a fast growth rate, the radioactive pulse labeled either all of the nuclei in a cell or none of them. at slower growth rates, hyphae contained both labeled and unlabeled nuclei. altering the growth rate thus changed nuclear replication from simultaneous to sequential. the time taken to ...19685669900
isolation of strains with increased penicillin yield after hybridization in aspergillus nidulans. 19685665723
quantitative intrachromosomal changes arising at mitosis in aspergillus nidulans. 19685664384
a radiation-sensitive mutant of aspergillus nidulans. 19685660770
[aspergillosis of the lung caused by aspergillus nidulans (eidam) wint]. 19685660496
regulation of sugar utilization by aspergillus nidulans. 19685660115
genetic fine structure and polarized negative inteference at the lys-51(fl) locus of aspergillus nidulans. 19685658755
purification and characterization of phosphatase i from aspergillus nidulans. 19685656385
regulation of choline sulphatase synthesis and activity in aspergillus nidulans.1. choline o-sulphate is taken up from the growth medium to the same extent by sulphur-deficient and sulphur-sufficient mycelia of aspergillus nidulans, but hydrolysis of the transported sulphate ester in vivo only occurs in the sulphur-deficient mycelia. 2. choline sulphatase activity could not be detected in vitro in sulphur-sufficient mycelia of wild-type and sulphur mutants of a. nidulans, but after sulphur starvation all strains showed appreciable activity of this enzyme. 3. optimum activit ...19685637354
mechanism of choline o-sulphate utilization in fungi.1. the position of the enzyme blocks in a number of parathiotrophic mutants of aspergillus nidulans a 69 and mutants a and c of a biotinless mutant of aspergillus nidulans were examined by nutritional and heterokaryosis experiments and by assay in vitro of enzyme systems and specific enzymes. 2. the mutants were in five groups: a and c blocked at sulphate transport; gamma at atp sulphurylase; iota at adenosine 5'-sulphatophosphate kinase; eta at the adenosine 3'-phosphate 5'-sulphatophosphate re ...19685637353
isolation from aspergillus nidulans, of a protein catalyzing the reduction of sulfite by reduced viologen dyes. 19675589532
aromatic amino acid biosynthesis and para-fluorophenylalanine resistance in aspergillus nidulans. 19675587942
a vegetative insatability in aspergillus nidulans. 19675586877
on the mechanism of mitotic recombination in aspergillus nidulans. ii. simultaneous recombination within two closely linked cistrons. 19675584174
on the mechanism of mitotic recombination in aspergillus nidulans. i. intragenic recombination and dna replication. 19675584173
gene-enzyme relationships in histidine biosynthesis in aspergillus nidulans. 19675583728
the genetic control of xanthine dehydrogenase and urate oxidase synthess in aspergillus nidulans. 19675583651
ultrastructure of aspergillus nidulans conidia and conidial lomasomes. 19715578692
sorbose resistant mutants of aspergillus nidulans. 19715564468
[mutagenic effect of ethyleneimine derivatives of pyrimidine on aspergillus nidulans]. 19715562879
another two genes controlling mitotic intragenic recombination and recovery from uv damage in aspergillus nidulans. ii. recombination behaviour and x-ray-sensitivity of uvsd and uvse mutants. 19715559679
a comparison of nucleotide sequences from mitochondrial and cytoplasmic ribosomal rna of aspergillus nidulans. 19715551626
methionine-sensitive leucine-requiring mutants of aspergillus nidulans. 19705518439
[the mutagenic effect of several alkylating substances on aspergillus nidulans]. 19705517360
[the mutagenic effect of alkylureides of diethylene imidophosphoric acid on aspergillus nidulans]. 19705517354
genetic and morphological properties of undifferentiated and invasive variants of aspergillus nidulans. 19705512361
recombination and transcription in the hisb and paba1 loci of aspergillus nidulans. 19705512357
a variegated position effect in aspergillus nidulans. 19705512256
a new class of slow-growing non-perithecial mutants of aspergillus nidulans. 19705512254
a mutation in aspergillus nidulans producing hyphal walls which lack chitin. 19705506575
genetic investigation of tryptophan-requiring mutants of aspergillus nidulans. 19705502333
control of ornithine-transcarbamylase formation in aspergillus nidulans. 19705501940
chemical composition of wild-type and mutant aspergillus nidulans cell walls. the nature of polysaccharide and melanin constituents. 19705500028
a study of aspects of heterokaryosis in aspergillus nidulans. 19705497573
regulation of lactose utilization in aspergillus nidulans. 19705495366
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