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[comparative study of flavonoids form crataegus oxyacantha l. and crataegus monogyna jacq]. 1977557870
[production of catechins and oligomeric proanthocyanidins in tissue and suspension cultures of crataegus monogyna, c. oxyacantha and ginkgo biloba (author's transl)]. 1977594203
on the coronary and cardiotonic action of crataemon.crataemon contains the purified flavonoid mixture of crataegus monogyna. flowmetric studies of dog coronary blood flow show that it increases after intravenous application of 2 mg/kg crataemon. this increase is statistically significant and lasts about 30 min, with no significant changes in the heart rate and ecg. in experiments on cats it has been found that only the high crataemon doses have a bradycardic effect. influence on the blood pressure is insignificant and brief. the minute cardiac vo ...1977614766
isocratic liquid chromatographic method for the simultaneous determination of passiflora incarnata l. and crataegus monogyna flavonoids in drugs. 19863711184
preliminary study of potential antiarrhythmic effects of crataegus monogyna. 19744455776
[studies on plant preservation in the temperature range of 20-100 degrees on crataegus monogyna jacq. i. quantitative measure of flavone heterosides]. 19685753728
[studies on the plant preservation in temperature range of 20-100 degrees on crataegus monogyna, jacq. ii. enzymatic degradation of flavone heterosides]. 19685753748
[new flavonoids from crataegus. 1. isolation of an acetylated vitexin-4'-rhamnoside from crataegus monogyna l]. 19655899815
immediate-type hypersensitivity to crataegus monogyna (hawthorn). 19846525827
antioxidant activities of crataegus monogyna extracts.interesting antioxidant activities of extracts from different vegetative and reproductive organs of crataegus monogyna harvested at different stages of growth have been determined by the malondialdehyde-thiobarbituric acid (mda) test on hepatic microsomal preparations and compared to the contents in total phenolics, proanthocyanidins, catechins, flavonoids, and phenolic acids. the best correlations were established with total phenols while activities in leaves seem to be influenced by flavonoids ...19947938266
oxygen species scavenging activity of phenolic extracts from hawthorn fresh plant organs and pharmaceutical preparations.different extracts of fresh vegetative and reproductive organs from crataegus monogyna harvested during a whole season and from some pharmaceutical hawthorn preparations exhibit in vitro antioxidant activities using three different models of oxygen reactive species generation (superoxide anion, hydrogen peroxide and hypochlorous acid). all the tested samples show low ic50 values, the most efficient being fresh young leaves, fresh floral buds and pharmaceutical dried flowers. the activities seem ...19968955870
antioxidant activities of polyphenolic extracts from flowers, in vitro callus and cell suspension cultures of crataegus monogyna.numerous plants synthesize among their secondary metabolites phenolic compounds which possess antioxidant effects. the aim of the present work was to assay the antioxidant activities of phenolics from crataegus monogyna jacq. flowers and in vitro tissue culture (calli and cell suspensions) extracts. in the case of tissue culture extracts, the phenolic production is studied at three different stages of one subculture period (initial growth period, increasing and maximal phenolic synthesis phases) ...19979035237
extracts from viscum and crataegus are cytotoxic against larynx cancer cells.the effects of hexanoic extracts of viscum cruciatum sieber parasitic on crataegus monogyna jacq. (i), crataegus monogyna jacq. parasitized with viscum cruciatum sieber (ii), and crataegus monogyna jacq. non-parasitized (iii), and of a triterpenes enriched fractions isolated from i, ii and iii (cfi, cfii, cfiii respectively), on the growth of hep-2 cells have been evaluated. all the samples demonstrated significant cytotoxic activity against cultured hep-2 cells, and all of them showed a stronge ...20099090065
the effects of a triterpene fraction isolated from crataegus monogyna jacq. on different acute inflammation models in rats and mice. leucocyte migration and phospholipase a2 inhibition.the plant crataegus monogyna has action against cardiac insufficiency, angina and arrhythmia. the anti-inflammatory properties of the cycloartenol fraction from this plant have been investigated. chromatographic fractionation of the hexane extract of crataegus monogyna jacq. (rosaceae) furnished a triterpene fraction containing cycloartenol as the main component (80.87%). the anti-inflammatory activity of the fraction was tested against hind-paw oedema induced by carrageenan in rats. at the high ...19979231356
inhibition of platelet aggregation and 5-ht release by extracts of australian plants used traditionally as headache treatments.to identify potential migraine therapeutics, extracts of eighteen plants were screened to detect plant constituents affecting adp induced platelet aggregation and [14c]5-hydroxytryptamine (5-ht) release. extracts of the seven plants exhibiting significant inhibition of platelet function were reanalysed in the presence of polyvinyl pyrrolidone (pvp) to remove polyphenolic tannins that precipitate proteins. two of these extracts no longer exhibited inhibition of platelet activity after removal of ...200010664475
a comparison of the composition of epicuticular wax from red raspberry (rubus idaeus l.) and hawthorn (crataegus monogyna jacq.) flowers.epicuticular waxes have been characterised from the flowers of raspberry and hawthorn, on both of which adult raspberry beetles (byturus tomentosus) can feed. the flower wax from both species had similar alkane profiles and also contained long-chain alcohols, aldehydes and fatty acids. the range of the carbon numbers detected for these classes of compounds was broadly similar in both but the relative amounts of each differed between species. raspberry flower wax also contained fatty acid methyl ...200011065285
lichens of the knyszyńska forest (ne poland).during the period 1991-1999 the lichen species composition of 26 reserves of the knyszyńska forest were examined. 315 taxa, including 271 species were found. epiphytic lichens were predominant, while epilithic species were the least common. of the coniferous trees, pine (pinus sylvestis) was the habitat which supported most species (67), and common larch (larix decidua) the fewest (5). only two species were found on juniper (juniper communis). of deciduous trees, the largest number of species de ...200111780570
influence of the parasite viscum cruciatum sieber on the chemical constituents of crataegus monogyna jacq.a phytochemical study of two plant species, viscum cruciatum sieber and crataegus monogyna jacq., was completed to investigate the influence of the parasite viscum cruciatum on the host crataegus monogyna. the study was carried out with two samples and consisted of hexane extracts of the viscum cruciatum parasitizing on crataegus monogyna and c monogyna. in these samples ursolic acid, beta-sitosterol and a triterpene fraction were found that contained mainly butyrospermol (3beta-lanost 8, 24-die ...201211837662
s-allele diversity in sorbus aucuparia and crataegus monogyna (rosaceae: maloideae).rt-pcr was used to obtain the first estimates from natural populations of allelic diversity at the rnase-based gametophytic self-incompatibility locus in the rosaceae. a total of 20 alleles were retrieved from 20 sorbus aucuparia individuals, whereas 17 alleles were found in 13 crataegus monogyna samples. estimates of population-level allele numbers fall within the range observed in the solanaceae, the only other family with rnase-based incompatibility for which estimates are available. the nucl ...200212180088
hawthorn.crataegus monogyna jacq (lindm), c. laevigata (poir) dc, or related crataegus species, collectively known as hawthorn, have been used in the treatment of cardiovascular diseases. clinical studies have found that standardized extracts show promise as adjunctive agents for the treatment of left ventricular dysfunction. other trials consistently demonstrate its ability to improve exercise tolerance and symptoms of mild to moderate heart failure. preliminary evidence indicates that it improves left ...200212597258
screening low fire blight susceptible crataegus species for host suitability to hawthorn leaf-curling aphids (dysaphis spp.).the group of hawthorn leaf-curling aphids (dysaphis spp.) hosted by the common hawthorn crataegus monogyna jacq. may play an important role in the biological control of the rosy apple aphid, dysaphis plantaginea (passerini), by increasing reproduction opportunities for the indigenous hymenopteran parasitoid ephedrus persicae froggatt. unfortunately, most fruitgrowers hesitate to introduce the common hawthorn in their orchards because they fear fire blight infections which may be transmitted by t ...200212696414
ozone air pollution and foliar injury development on native plants of switzerland.the objectives of this study were to examine the foliar sensitivity to ozone exposure of 12 tree, shrub, and herbaceous species native to southern switzerland and determine the seasonal cumulative ozone exposures required to induce visible foliar injury. the study was conducted from the beginning of may through the end of august during 2000 and 2001 using an open-top chamber research facility located within the lattecaldo cantonal forest nursery in canton ticino, southern switzerland (600 m asl) ...200312804826
antioxidant capacity of polyphenolic extracts from leaves of crataegus laevigata and crataegus monogyna (hawthorn) subjected to drought and cold stress.crataegus laevigata and crataegus monogyna (hawthorn) were subjected to drought and cold stress treatments, and polyphenolic extracts from control and stress-treated plants were assayed for antioxidant capacities using a modified version of the total antioxidant status assay (randox, san francisco, ca). in addition, these plants were analyzed for levels of flavanol-type substance [(-)-epicatechin] and flavonoid (vitexin 2' '-o-rhamnoside, acetylvitexin 2' '-o-rhamnoside, and hyperoside) constitu ...200312822932
phenolic constituents and antioxidant capacities of crataegus monogyna (hawthorn) callus extracts.crataegus (hawthorn) has long been used as a folk medicine and is widely utilized in pharmaceutical preparations mainly because of its neuro- and cardiosedative actions and its low toxicity. the pharmacological effects of crataegus have mainly been attributed to the polyphenolic contents. in this study, the production of polyphenols by ten-year-old crataegus monogyna calli was studied in relation to growth variation and antioxidant capacity within a subculture period. assays based on the trolox ...200312866623
stomatal responses to drought at a mediterranean site: a comparative study of co-occurring woody species differing in leaf longevity.we studied stomatal responses to decreasing predawn water potential (psipd) and increasing leaf-to-air water vapor pressure difference (vpd) of co-occurring woody mediterranean species with contrasting leaf habits and growth form. the species included two evergreen oaks (quercus ilex subsp. ballota (desf.) samp. and q. suber l.), two deciduous oaks (q. faginea lam. and q. pyrenaica willd.) and two deciduous shrubs (pyrus bourgaeana decne. and crataegus monogyna jacq.). our main objective was to ...200312952785
[estimation of maximum acceptable concentration of lead and cadmium in plants and their medicinal preparations].heavy metals (lead, cadmium) are possible dashes which quantity is defined by the limiting acceptable contents. different drugs preparations: infusions, decoctions, tinctures, extracts, etc. are produced using medicinal plants. the objective of this research was to study the impurities of heavy metals (lead, cadmium) in medicinal plants and some drug preparations.200314617871
the mathematical treatment of leaf venation: the variation in secondary vein length along the midrib.in some dicotyledonous leaves and leaflets, the secondary veins run more-or-less straight to the margins and have well-defined lengths. for a given half-lamina of length l, an equation, previously proposed, relates the lengths of these veins, p, to the distances, l, between the leaf tip and their insertions on the midrib: p = b2(x+y)l(x)(l - l)(y)/l(x+y-1), where b, x and y are fitted parameters. aspects of the formula are re-examined, including its general applicability, significance and useful ...200414707000
[research of the amounts of flavonoids accumulated in the buds of single-styled hawthorn].to determine the amounts of flavonoids accumulated in the buds of single-styled hawthorn (crataegus monogyna jacq.); and to establish the possibility of usage of hawthorn buds in pharmacy practice.200415299992
[phytotherapy tested in heart-healthy seniors. more vital with crataegus monogyna]. 200415526637
phenological observations on shrubs to predict weed emergence in turf.phenology is the study of periodic biological events. if we can find easily recognizable events in common plants that precede or coincide with weed emergences, these plants could be used as indicators. weed seedlings are usually difficult to detect in turf, so the use of phenological indicators may provide an alternative approach to predict the time when a weed appears and consequently guide management decisions. a study was undertaken to determine whether the phenological phases of some plants ...200515846520
rodent seed predation promotes differential recruitment among bird-dispersed trees in temperate secondary forests.we investigated the role of seed predation by rodents in the recruitment of the fleshy-fruited trees taxus baccata, ilex aquifolium and crataegus monogyna in temperate secondary forests in nw spain. we measured the densities of dispersed seeds, early emerged seedlings, established recruits and adults, at four sites over a period of 2 years. seed predation among species was compared by seed removal experiments and analysis of rodent larder-hoards. the three species differed markedly in local rege ...200515891859
metsulfuron spray drift reduces fruit yield of hawthorn (crataegus monogyna l.).this study was carried out to investigate whether spray drift of metsulfuron has a potential to negatively affect hawthorn (crataegus monogyna) hedgerows near agricultural fields. for this purpose four doses of metsulfuron ranging from 5% to 40% of the field dose (4 g metsulfuron per hectare) were sprayed on trees in seven different hawthorn hedgerows. the actual deposition on the leaves was measured by means of a tracer (glycine). spraying was conducted both at the bud stage and at early flower ...200615893364
capillary electrophoretic analysis of flavonoids in single-styled hawthorn (crataegus monogyna jacq.) ethanolic extracts.flavonoids are an important group of natural compounds, which can prevent coronary heart disease and have antioxidant properties. hawthorn is a well known and widely used medicinal plant due to its cardiotonic activity. previous studies refer mostly to the hplc analysis of the flavonoids: vitexin, quercetin, hyperoside, oligomeric procyanidins, which appear to be primarily responsible for the cardiac action of the plant. aqueous ethanolic extracts of single-styled hawthorn (crataegus monogyna ja ...200616443232
the gathering and consumption of wild edible plants in the campoo (cantabria, spain).this paper discusses the traditional consumption of wild edible plants in the rural communities of the campoo (cantabria), a region in northern spain. through semi-structured interviews with key informants, data on the perception, gathering, preparation and use of 60 edible wild plant species were collected. social, economic and cultural factors need to be taken into account when trying to understand why some wild foods and traditional vegetables continue to be consumed while others are not. wil ...200516503563
correlation between the in vitro antioxidant activity and polyphenol content of aqueous extracts from bulgarian herbs.the water phase antioxidant activity of extracts from 23 bulgarian medicinal plants was studied in relation to their polyphenol content in comparison with mate, black tea, honeybush and rooibos foreign species. antioxidant activity was measured by the abts (2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)) cation radical decolorization assay, and the total polyphenol content was assayed according to the folin-ciocalteu method. five bulgarian plant extracts exhibited higher antioxidant activ ...200616906640
production of flavonoids in cell cultures of crataegus monogyna.callus and suspension cultures were established from shoot tips of crataegus monogyna l. in murashige and skoog (ms) medium and a modified ms medium. the flavonoid glycosides vitexin, vitexin 2- o-rhamnoside, rutin, and hyperoside, as well as the aglycones apigenin, luteolin, and quercetin, could be detected by tlc and hplc in, however, varying amounts. additionally, the contents of procyanidins were determined. the ratio between the contents of flavonoids and procyanidins is discussed.199317230364
seasonal and interannual variability of canopy transpiration of a hedgerow in southern england.transpiration from a hawthorn (crataegus monogyna l.) dominated hedgerow in southern england was measured continuously over two growing seasons by the sap flow technique. accompanying measurements of structural parameters, microclimate and leaf stomatal and boundary layer conductances were used to establish the driving factors of hedgerow transpiration. observed transpiration rates, reaching peak values of around 8 mm day(-1) and a seasonal mean of about 3.5 mm day(-1), were higher than those re ...200717241974
scale-dependent effects of habitat fragmentation on hawthorn pollination, frugivory, and seed predation.habitat fragmentation is a major cause of functional disruption in plant-animal interactions. the net effect on plant regeneration is, however, controversial because a given landscape change can simultaneously hamper mutualism and attenuate antagonism. furthermore, fragmentation effects may emerge at different spatial scales, depending on the size of the foraging range of the different interacting animals. we studied pollination by insects, frugivory by birds acting as seed dispersers, and postd ...200717391190
[new flavonoid-glycosides from crataegus monogyna and crataegus pentagyna].from the leaves and flowers of crataegus monogyna and c. pentagyna six new flavonoid-c- and o-glycosides respectively have been isolated and identified as 2''-o-rhamnosyl-orientin, 2''-o-rhamnosyl-isoorientin, 2''-o-rhamnosyl-isovitexin, rutin, spiraeosid, 8-methoxy-kämpferol and 8-methoxy-kämpferol-3-o-glucoside. the structure of o-rhamnosyl-vitexin and o-acetyl-o-rhamnosyl-vitexin isolated previously, have been elucidated unambigiously mainly by nmr- and ms-spectroscopy.198217402083
variability of total flavonoids in crataegus--factor evaluation for the monitored production of industrial starting material.european hawthorn species (crataegus spp.) are traditionally used for their demonstrated cardioprotective benefits. most products are based on the compendial leaf and flower drug (lfd), which is standardised on the total flavonoid content (tf). in order to reduce variability associated with the wild plant origin and to ease product standardisation, we set out to develop a sustainable source of high quality raw material. firstly, the lfd of wild trees in germany was screened in terms of tf conten ...200817706370
radioprotective properties of the phytochemically characterized extracts of crataegus monogyna, cornus mas and gentianella austriaca on human lymphocytes in vitro.the objective of the present study is to evaluate the radioprotective properties of extracts of crataegus monogyna jacq. (rosaceae) fruit, cornus mas l. (cornaceae) leaves and gentianella austriaca (a. kern. & jos. kern.) holub (gentianaceae) aerial parts on cultured human peripheral blood lymphocytes in vitro after irradiation with 2 gy of 60co gamma-rays. plants were collected at mt. maljen in serbia, air-dried and powdered, and the total phenolic content was analyzed. in c. mas leaves, ellagi ...200717764067
ecophysiological competence of populus alba l., fraxinus angustifolia vahl., and crataegus monogyna jacq. used in plantations for the recovery of riparian vegetation.in many semi-arid environments of mediterranean ecosystems, white poplar (populus alba l.) is the dominant riparian tree and has been used to recover degraded areas, together with other native species, such as ash (fraxinus angustifolia vahl.) and hawthorn (crataegus monogyna jacq.). we addressed three main objectives: (1) to gain an improved understanding of some specific relationships between environmental parameters and leaf-level physiological factors in these riparian forest species, (2) to ...200717849159
4'''-acetylvitexin-2''-o-rhamnoside, isoorientin, orientin, and 8-methoxykaempferol-3-o-glucoside as markers for the differentiation of crataegus monogyna and crataegus pentagyna from crataegus laevigata (rosaceae).in our chemotaxonomic investigation of pharmaceutically relevant crataegus species, the qualitative and quantitative flavonoid fingerprint of crataegus monogyna and c. pentagyna is presented. six flavonoids were identified as vitexin-2''-o-rhamnoside (1), vitexin (2), isovitexin (3), rutin (4), hyperoside (5), and isoquercitrin (6). besides the verification of the main compounds isoorientin (7) and orientin (8) in c. pentagyna, further four flavonoids were isolated and identified as isoorientin- ...200718081102
influence of the extraction mode on the yield of hyperoside, vitexin and vitexin-2''-o-rhamnoside from crataegus monogyna jacq. (hawthorn).the extract of crataegus monogyna shows sedative, hypotensive, vasodilator and cardio-tonic actions. although several papers dealing with the extraction of metabolites from crataegus have been published, the plant productivity in terms of bioactive compounds is not easily understandable as yet.201618618435
hawthorn (crataegus monogyna jacq.) extract exhibits atropine-sensitive activity in a cultured cardiomyocyte assay.hawthorn (crataegus spp.) plant extract is used as a herbal alternative medicine for the prevention and treatment of various cardiovascular diseases. recently, it was shown that hawthorn extract preparations caused negative chronotropic effects in a cultured neonatal murine cardiomyocyte assay, independent of beta-adrenergic receptor blockade. the aim of this study was to further characterize the effect of hawthorn extract to decrease the contraction rate of cultured cardiomyocytes. to test the ...200918696181
anti-inflammatory, gastroprotective, free-radical-scavenging, and antimicrobial activities of hawthorn berries ethanol extract.hawthorn [crataegus monogyna jacq. and crataegus oxyacantha l.; sin. crataegus laevigata (poiret) dc., rosaceae] leaves, flowers, and berries are used in traditional medicine in the treatment of chronic heart failure, high blood pressure, arrhythmia, and various digestive ailments, as well as geriatric and antiarteriosclerosis remedies. according to european pharmacopoeia 6.0, hawthorn berries consist of the dried false fruits of these two species or their mixture. the present study was carried ...200818698794
free radical-scavenging activities of crataegus monogyna extracts.the aim of this study was to investigate antiradical activity of aqueous and ethanolic hawthorn fruit extracts, their flavonoids, and flavonoid combinations.200818971609
seed dispersal patterns in a temperate forest during a mast event: performance of alternative dispersal kernels.seed dispersal patterns were studied in a north-western spain temperate forest community to assess the performances of alternative dispersal kernels during two years with ecologically contrasting scenarios; a non-mast year, and a mast year of the dominant canopy species, beech fagus sylvatica. dispersal kernels were fitted under a bayesian modeling framework. both simple and mixture kernels were considered for the five more abundant tree species (corylus avellana, crataegus monogyna, f. sylvatic ...200919018573
determination of antioxidant effects of some plant species wild growing in turkey.in this study, the antioxidant activity of 50% aqueous methanol extracts of crataegus tanacetifolia (lam.) pers, crataegus bornmuelleri zaberi, crataegus orientalis pall. ex m.bieb. var. orientalis, crataegus szovitsii pojark, crataegus curvisepala lindm., crataegus monogyna jacq. subsp. monogyna, crataegus monogyna jacq.subsp. azarella (gris.) franco, crataegus micophylla c.koch, rosa foetida herrm., rosa hemisphaerica j.herrm., rosa pulverulenta m.bieb., rosa canina l., rubus discolor weihe & ...200819382350
investigation of contribution of individual constituents to antioxidant activity in herbal drugs using postcolumn hplc method.the most important attention is paid to the search of natural antioxidants and their evaluation in medicinal and food raw materials of plant origin. a number of plants, their extracts, food products, and medicinal preparations appear to be the objects of scientific research. effectiveness and informative character of research, undoubtedly, depend on relevance, sensitivity, and efficiency of the methods chosen. the aim of this work was to develop and validate the postcolumn high-performance liqui ...200919535885
the comparison of anti-oxidative kinetics in vitro of the fluid extract from maidenhair tree, motherwort and hawthorn.the aim of the study was to perform a quantitative analysis of fluid extracts of maidenhair tree (ginkgo biloba l.), motherwort (leonurus cardiaca l.) and hawthorn (crataegus monogyna jacq.), to evaluate their antioxidant activity and to compare their ability to inactivate free radicals. the antioxidant activity was measured using the dpph*and the abts*+ radical scavenging reaction systems. the study showed that the manifestation of the radical scavenging capacity in the dpph* reaction system wa ...201619702174
pollination biology of fruit-bearing hedgerow plants and the role of flower-visiting insects in fruit-set.in the uk, the flowers of fruit-bearing hedgerow plants provide a succession of pollen and nectar for flower-visiting insects for much of the year. the fruits of hedgerow plants are a source of winter food for frugivorous birds on farmland. it is unclear whether recent declines in pollinator populations are likely to threaten fruit-set and hence food supply for birds. the present study investigates the pollination biology of five common hedgerow plants: blackthorn (prunus spinosa), hawthorn (cra ...200919770165
tryptophan depletion and formation of alpha-aminoadipic and gamma-glutamic semialdehydes in porcine burger patties with added phenolic-rich fruit extracts.the effect of added fruit extracts on the oxidation of muscle proteins in porcine burger patties subjected to cooking and chill storage was studied. extracts from arbutus berries (arbutus unedo l., au), common hawthorns (crataegus monogyna l., cm), dog roses (rosa canina l., rc), and elm-leaf blackberries (rubus ulmifolius schott, ru) were prepared, characterized, added to burger patties (3% of total weight), and evaluated as inhibitors of protein oxidation. negative (no added extract, c) and po ...201020170109
effects of forest fragmentation on seed dispersal and seedling establishment in ornithochorous trees.habitat fragmentation increases seed dispersal limitation across the landscape and may also affect subsequent demographic stages such as seedling establishment. thus, the development of adequate plans for forest restoration requires an understanding of mechanisms by which fragmentation hampers seed delivery to deforested areas and knowledge of how fragmentation affects the relationship between seed-deposition patterns and seedling establishment. we evaluated the dispersal and recruitment of two ...201020184646
six edible wild fruits as potential antioxidant additives or nutritional supplements.total antioxidant activity of six non-cultivated but traditionally collected fruits from the south of europe was assessed by measuring their ability to reduce the hydroxyl radical (oh) and hydrogen peroxide (h(2)o(2)), and their trolox equivalent antioxidant capacity (teac). this antioxidant activity was compared with that shown by the synthetic antioxidants bha (e-320), bht (e-321) and propyl gallate (e-310). total phenolics, ascorbic acid and the carotenoid content of the fruits were also anal ...201020198440
genetic relationships among some hawthorn (crataegus spp.) species and genotypes.the genus crataegus is well distributed in turkey as a wild plant, with numerous, inherently variable species and genotypes. rapd markers were used to study 17 hawthorn genotypes belonging to crataegus monogyna ssp. monogyna jacq (2 genotypes), c. monogyna ssp. azarella jacq (1), crataegus pontica k.koch (3), crataegus orientalis var. orientalis pallas ex bieb (3), crataegus pseudoheterophylla pojark (1), crataegus aronia var. dentata browicz (1), c. aronia var. aronia browicz (4), and crateagus ...201020640884
the evaluation of formulations for the preparation of new formula pellets.the aim of the study was to prepare pellets of maidenhair tree (ginkgo biloba), motherwort (leonurus cardiaca) and hawthorn (crataegus monogyna) dry extracts by extrusion/spheronization method. the critical step of this process was the amount of added wetting liquid (water-ethanolic mixture) and the amount of extract in the formulation. the samples of pellets containing 30-50% of extracts were formulated: pellets contained extracts of ginkgo, crataegi and leonuri. the last sample was aimed at th ...201120649408
effects of hawthorn seed and pulp extracts on the central nervous system.investigating potential central nervous system (cns) activities of crataegus monogyna jacq. (rosaceae), hawthorn, fruit extracts. objective: evaluating cns effects and analgesic activities of hawthorn fruit extracts based on the traditional uses of the plant for neurosedative and pain killer actions.201020673180
characterization of selected wild mediterranean fruits and comparative efficacy as inhibitors of oxidative reactions in emulsified raw pork burger patties.in the present study, water, ethanolic, and methanolic extracts from seven selected wild fruits originally from the mediterranean area, namely, strawberry tree ( arbutus unedo l., au), azarole ( crataegus azarolus l., ca), common hawthorn ( crataegus monogyna l., cm), blackthorn ( prunus spinosa l., ps), dog rose ( rosa canina l., rc), elm-leaf blackberry ( rubus ulmifolius schott, ru), and rowan ( sorbus aucuparia l., sa), were analyzed for the total amount and profile of phenolic compounds and ...201020681673
comparing the composition and bioactivity of crataegus monogyna flowers and fruits used in folk medicine.studying local plant foods is of particular interest as they often contain high amounts of bioactive compounds. furthermore, their nutritional and medicinal impact must be documented and supported with scientific studies. crataegus monogyna is an example of 'functional food' traditionally used all over south european countries.201120848392
correlation of xmap and elisa cytokine profiles; development and validation for immunotoxicological studies in vitro.there is an emerging trend in immunotoxicological studies to use the multiplex technologies for testing the safety and the efficacy of new pharmaceuticals by using cytokines profiling as biomarker. the luminex 200 xmap (multi-analyte profiling) technology provides simultaneous measurement of multiple cytokines in small sample volumes, expressing rapidly the differences between various test compounds. the aim is to develop and validate the luminex 200 multiplex immunoassays by correlation with el ...201021053779
hawthorn--crataegus monogyna (common hawthorn) or crataegus laevigata (midland hawthorn; crataegus oxyacantha); also known as haw, thornapple, maythorn, whitethorn. 201121359265
honeybees increase fruit set in native plant species important for wildlife conservation.honeybee colonies are declining in some parts of the world. this may have important consequences for the pollination of crops and native plant species. in spain, as in other parts of europe, land abandonment has led to a decrease in the number of non professional beekeepers, which aggravates the problem of honeybee decline as a result of bee diseases in this study, we investigated the effects of honeybees on the pollination of three native plant species in northern spain, namely wildcherry prunu ...201121519875
assessment of phenolic acid content and in vitro antiradical characteristics of hawthorn.the infusions and extracts obtained from leaves with flowers, fruit peel, and seed from hawthorn (crataegus monogyna jacq., family rosaceae) were subjected to evaluation as potential sources of antioxidant phytochemicals on the basis of their total content of phenolics, levels of phenolic acids, and in vitro antiradical activity. total phenolic content of extracts was determined using the modified folin-ciocalteau method. antioxidant activity was determined for phenolic extracts by a method invo ...201121554133
crataegus monogyna aqueous extract ameliorates cyclophosphamide-induced toxicity in rat testis: stereological evidences.cyclophosphamide (cp) is extensively used as an antineoplastic agent for the treatment of various cancers, as well as an immunosuppressive agent. however, despite its wide spectrum of clinical uses, cp is known to cause several adverse effects including reproductive toxicity. crataegus monogyna is one of the oldest pharmaceutical plants that have been shown to be cytoprotective by scavenging free radicals. the present study was conducted to assess whether crataegus monogyna fruits aqueous extrac ...201222267371
bioactive compounds, rp-hplc analysis of phenolics, and antioxidant activity of some portuguese shrub species extracts.in the ecosystem of serra da estrela, some plant species have the potential to be used as raw material for extraction of bioactive products. the goal of this work was to determine the phenolic, flavonoid, tannin and alkaloid contents of the methanolic extracts of some shrubs (echinospartum ibericum, pterospartum tridentatum, juniperus communis, ruscus aculeatus, rubus ulmifolius, hakea sericea, cytisus multiflorus, crataegus monogyna, erica arborea and ipomoea acuminata), and then to correlate t ...201122312726
characterization of phenolic compounds in flowers of wild medicinal plants from northeastern portugal.crataegus monogyna, cytisus multiflorus, malva sylvestris and sambucus nigra have been used as important medicinal plants in the iberian peninsula since a long time ago, and are claimed to have various health benefits. this study aimed to determine the phenolic profile and composition of wild medicinal flowers of those species. the analysis was performed by hplc-dad-esi/ms. flavonoids, and particularly flavonols and flavones, were the main groups in almost all the studied samples. c. multiflorus ...201222342808
phytochemical characterization of several hawthorn (crataegus spp.) species sampled from the eastern mediterranean region of turkey.we evaluated the total phenolic content, antioxidant capacity as well as antioxidant activity of five crataegus species (a1, a2, y1, y2, y4 accessions of crataegus aronia var. aronia; b2, b3, b5, b6, b7, b9, y5 accessions of c. aronia var. dentata; b10 accession of c. aronia var. minuta; y3 accession of crataegus orientalis var. orientalis and a3 accession of crataegus monogyna subsp. azarella).201222438658
a simple gc-ms method for the screening of betulinic, corosolic, maslinic, oleanolic and ursolic acid contents in commercial botanicals used as food supplement ingredients.the occurrence of triterpene pentacyclic acids in plants is extensive, but little is known about their availability in commercial extracts. a simple gc-ms method for the simultaneous determination of betulinic, corosolic, maslinic, oleanolic and ursolic acids was developed and applied to 38 different commercial plant extracts sold as ingredients for dietary supplements. a suitable protocol was set up to perform routine control of a diverse array of samples with different botanical, chemical and ...201323122121
formulation of microspheres containing crataegus monogyna jacq. extract with free radical scavenging activity.extracts of crataegus monogyna jacq. (hawthorn) show an interesting free radical scavenging (frs) effect, related to their flavonoids content. unfortunately, their oral administration is affected by their low bioavailability. the aim of this work is to obtain a multiparticulate drug delivery system for hawthorn extracts for oral administration. the extracts from flowering tops (fl) or fruits (fr) of hawthorn were obtained with maceration, using ethanol as an extraction solvent, and their antioxi ...201423301945
a strategy for the identification of plants in illegal pharmaceutical preparations and food supplements using chromatographic fingerprints.the detection of regulated and forbidden herbs in pharmaceutical preparations and nutritional supplements is a growing problem for laboratories charged with the analysis of illegal pharmaceutical preparations and counterfeit medicines. this article presents a feasibility study of the use of chromatographic fingerprints for the detection of plants in pharmaceutical preparations. fingerprints were developed for three non-regulated common herbal products--rhamnus purshiana, passiflora incarnata l. ...201323307125
antioxidant capacity and hplc-dad-ms profiling of chilean peumo (cryptocarya alba) fruits and comparison with german peumo (crataegus monogyna) from southern chile.liquid chromatography (lc) coupled with uv detection and electrospray ionization (esi) tandem mass spectrometry (ms/ms) was used for the generation of chemical fingerprints and the identification of phenolic compounds in peumo fruits and aerial parts from southern chile. thirty three compounds (19 of these detected in c. alba and 23 in c. monogyna) were identified, mainly flavonoid glycosides, phenolic acids, anthocyanins and flavonoid aglycons. total phenolic content and total flavonoid content ...201323385342
where do seeds go when they go far? distance and directionality of avian seed dispersal in heterogeneous landscapes.seed dispersal at large scales strongly influences plant population dynamics. still, ecologists have rarely measured seed dispersal at relevant scales, and the role of habitat types in affecting seed dispersal at long distances remains unexplored. we studied seed dispersal of ilex aquifolium and crataegus monogyna in northern spain, hypothesizing that seeds would be recovered at higher rates and at longer distances (ldd) at habitats with fleshy-fruited trees, compared to habitats with other tree ...201323691649
assessment of extracts of helichrysum arenarium, crataegus monogyna, sambucus nigra in photoprotective uva and uvb; photostability in cosmetic emulsions.the aim of our study was to investigate the photoprotective activity and photostability efficacy of sunscreen formulations containing helichrysum arenarium, sambucus nigra, crataegus monogyna extracts and their combination. uv transmission of the emulsion films was performed by using diffuse transmittance measurements coupling to an integrating sphere. in vitro photoprotection and photostability efficacy were evaluated according to the following parameters: sun protection factor (spf), uva prote ...201324007865
attenuation of cyclosporine-induced sperm impairment and embryotoxicity by crataegus monogyna fruit aqueous extract.cyclosporine (cs), a cyclic undecapeptide with potent immuno suppressive activity, causes several adverse effects including reproductive toxicity. this study aims to examine the ability of crataegus monogyna aqueous fruit extract as an antioxidant to protect against cs-induced reproductive toxicity.201324027659
selective pressure along a latitudinal gradient affects subindividual variation in plants.individual plants produce repeated structures such as leaves, flowers or fruits, which, although belonging to the same genotype, are not phenotypically identical. such subindividual variation reflects the potential of individual genotypes to vary with micro-environmental conditions. furthermore, variation in organ traits imposes costs to foraging animals such as time, energy and increased predation risk. therefore, animals that interact with plants may respond to this variation and affect plant ...201324069297
comparative analysis of tunisian wild crataegus azarolus (yellow azarole) and crataegus monogyna (red azarole) leaf, fruit, and traditionally derived syrup: phenolic profiles and antioxidant and antimicrobial activities of the aqueous-acetone extracts.quantitative and qualitative analyses of the yellow and red azarole phenolic extracts prepared from leaf, fruit peel/pulp, and syrup were comparatively investigated. the yellow azarole was found significantly richer in polyphenols than the red-fruit species. hyperoside was the main phenolic in both yellow and red azarole leaves and only in yellow fruits, whereas procyanidin b2 was the major compound in red fruits. yellow azarole leaf and fruit peel extracts exhibited the strongest antioxidant ac ...201324070066
seed predators exert selection on the subindividual variation of seed size.subindividual variation among repeated organs in plants constitutes an overlooked level of variation in phenotypic selection studies, despite being a major component of phenotypic variation. animals that interact with plants could be selective agents on subindividual variation. this study examines selective pressures exerted during post-dispersal seed predation and germination on the subindividual variation of seed size in hawthorn (crataegus monogyna). with a seed offering experiment and a germ ...201424176051
crataegus ×ninae-celottiae and c. ×cogswellii (rosaceae, maleae), two spontaneously formed intersectional nothospecies.crataegus monogyna jacq. is naturalized in north america, where it has hybridized with native diploid hawthorns at least twice. we provide names for the two nothospecies (as well as for the corresponding nothosections and nothoseries), referring to existing documentation in the literature for nothosp. nov. crataegus ×ninae-celottiae k.i. chr. & t.a. dickinson (c. monogyna × c. punctata jacq.). new data are provided to further document nothosp. nov. crataegus ×cogswellii k.i. chr. & t.a. dickinso ...201424843290
antioxidant, antimicrobial and neutrophil-modulating activities of herb extracts.the present study provides a comprehensive data on the antioxidant, antimicrobial and neutrophil-modulating activities of extracts from six medicinal plants--blackberry (rubus fruticosus) leaves, chokeberry (aronia melanocarpa) leaves, hawthorn (crataegus monogyna) leaves, lady's mantle (alchemilla glabra) aerial parts, meadowsweet (filipendula ulmaria) aerial parts and raspberry (rubus idaeus) leaves. in order to analyze the antioxidant activity of the herbs, several methods (orac, trap, horac ...201424945135
crataegus monogyna fruit aqueous extract as a protective agent against doxorubicin-induced reproductive toxicity in male rats.doxorubicin (dox) is a broad spectrum chemotherapeutic agent used in the treatment of several malignancies. the use of dox in clinical chemotherapy has been restricted due to its diverse toxicities, including reproductive toxicity. crataegus monogyna (c. monogyna) is one of the oldest medicinal plants that have been shown to be cytoprotective because of scavenging free radicals. the present study was undertaken to determine whether c. monogyna fruits aqueous extract could serve as a protective a ...201325050270
influence of extraction technique on the anti-oxidative potential of hawthorn (crataegus monogyna) extracts in bovine muscle homogenates.six extracts were prepared from hawthorn (crataegus monogyna) leaves and flowers (hlf) and berries (hb) using solid-liquid [traditional (t) (hlft, hbt), sonicated (s) (hlfs, hbs)] and supercritical fluid (c) extraction (hlfc, hbc) techniques. the antioxidant activities of hlf and hb extracts were characterised using in vitro antioxidant assays (tpc, dpph, frap) and in 25% bovine muscle (longissimus lumborum) homogenates (lipid oxidation (tbars), oxymyoglobin (% of total myoglobin)) after 24h sto ...201425170819
evaluation of the antithrombotic effects of crataegus monogyna and crataegus davisii in the carrageenan-induced tail thrombosis model.crataegus species are widely used as herbal medicines for preventing cardiovascular diseases (cvds). however, there are no studies on the effects of crataegus monogyna jacq. (rosaceae) and c. davisii browicz on thrombosis, which is an important mechanism in cvds.201525243870
habitat and forage associations of a naturally colonising insect pollinator, the tree bumblebee bombus hypnorum.bumblebees (bombus species) are major pollinators of commercial crops and wildflowers but factors affecting their abundance, including causes of recent population declines, remain unclear. investigating the ecology of species with expanding ranges provides a potentially powerful means of elucidating these factors. such species may also bring novel pollination services to their new ranges. we therefore investigated landscape-scale habitat use and foraging preferences of the tree bumblebee, b. hyp ...201425259579
stem co2 efflux in six co-occurring tree species: underlying factors and ecological implications.stem respiration plays a role in species coexistence and forest dynamics. here we examined the intra- and inter-specific variability of stem co2 efflux (e) in dominant and suppressed trees of six deciduous species in a mixed forest stand: fagus sylvatica l., quercus petraea [matt.] liebl, quercus pyrenaica willd., prunus avium l., sorbus aucuparia l. and crataegus monogyna jacq. we conducted measurements in late autumn. within species, dominants had higher e per unit stem surface area (es ) main ...201525292455
antimicrobial constituents from three endophytic fungi.to evaluate the antimicrobial potential of extracts of the endophytic fungi plectophomella sp., physalospora sp., and crataegus monogyna (c. monogyna) and study the tentative identification of their active constituents.201425312126
metal characterization of white hawthorn organs and infusions.hawthorn is one of the most commonly used european and north american phytopharmaceuticals. because there is no information on metals in seeds, and only rare data for leaves and flowers, the aim of the present study was elemental analysis of the white hawthorn (crataegus monogyna) by inductively coupled plasma emission spectrometry (icp-aes) or inductively coupled plasma mass spectrometry (icp-ms) after digestion in a microwave-assisted system. the limits of detection are below 2 μg/g for icp-ae ...201525630398
isolation and quantification of oligomeric and polymeric procyanidins in leaves and flowers of hawthorn (crataegus spp.).proanthocyanidins (pas) constitute a class of polyphenols with flavan-3-ols as monomeric building blocks. these polyphenols are mostly quantified by colorimetric methods or by chromatographic determination of monomeric flavan-3-ols or low molecular oligomers as lead compounds. no reliable analytical methods are available for unambiguous identification of the homologues series of oligo- and polymeric pas. for hawthorn leaf and flower (crataegi folium cum flore) from crataegus spp. (rosaceae) a pr ...201525917901
[investigation of metal element content of some european and far eastern herbs].metal elements and their excess intake have significant influence on general health.201526211750
using dna metabarcoding to identify the floral composition of honey: a new tool for investigating honey bee foraging preferences.identifying the floral composition of honey provides a method for investigating the plants that honey bees visit. we compared melissopalynology, where pollen grains retrieved from honey are identified morphologically, with a dna metabarcoding approach using the rbcl dna barcode marker and 454-pyrosequencing. we compared nine honeys supplied by beekeepers in the uk. dna metabarcoding and melissopalynology were able to detect the most abundant floral components of honey. there was 92% corresponden ...201526308362
hawthorn ethanolic extracts with triterpenoids and flavonoids exert hepatoprotective effects and suppress the hypercholesterolemia-induced oxidative stress in rats.the current study was aimed to determine the bioactive constituents and biological effects of the crataegus monogyna ethanolic extracts from bark, leaves and berries on hypercholesterolemia.201526361538
polyphenolic composition of crataegus monogyna jacq.: from chemistry to medical applications.the abundance of scientific evidence has shown that many synthetic drugs can cause serious adverse effects in patients. recently, the search of natural therapeutic agents with low adverse effects has attracted much attention. in particular, considerable interest has focused on edible and medicinal plants, which play an important role in human diet, and have been used for disease treatment since ancient times. crataegus monogyna jacq. (hawthorn) is one of the most important edible plants of the r ...201526378574
the investigation of some bioactive compounds and antioxidant properties of hawthorn (crataegus monogyna subsp. monogyna jacq).the antioxidant and pharmacological effects of hawthorn have mainly been attributed to the polyphenolic contents. the aim of this research is to determine some bioactive compounds and antioxidant properties of hawthorn aqueous and ethanol extracts of leaves, flowers, and ripened fruits.201726401347
rapid and repeatable shifts in life-history timing of rhagoletis pomonella (diptera: tephritidae) following colonization of novel host plants in the pacific northwestern united states.host shifts of phytophagous insect specialists to novel plants can result in divergent ecological adaptation, generating reproductive isolation and potentially new species. rhagoletis pomonella fruit flies in eastern north america underwent a host shift ~160 ya from native downy hawthorn (crataegus mollis) to introduced, domesticated apple (malus domestica). divergent selection on diapause phenology related to the earlier fruiting time of apples versus downy hawthorns resulted in partial allochr ...201526811757
physico-chemical, antioxidant, and anti-inflammatory properties and stability of hawthorn (crataegus monogyna jacq.) procyanidins microcapsules with inulin and maltodextrin.procyanidins from the bark of hawthorn (crataegus monogyna jacq.) were isolated and purified. qualitative and quantitative composition was compared with that of the extract of hawthorn fruit (crataegus monogyna jacq.). stability and antioxidant and anti-inflammatory properties of procyanidins before and after micro-encapsulation were estimated. the effects of the carrier type (inulin and maltodextrin) and procyanidins:carrier ratio (1:1, 1:3) and the influence of storage temperature (20 °c, -20 ...201727145129
geographic origin influences the phenolic composition and antioxidant potential of wild crataegus monogyna from spain.crataegus monogyna jacq l. (lind.) (rosaceae) is used in folk medicine as a sedative, aerial parts being rich in polyphenols with antioxidant ability.201627226067
in vitro measurement of total antioxidant capacity of crataegus macracantha lodd leaves.crataegus macracantha lodd, family rosaceae, is a very rare species in europe, and unlike crataegus monogyna is less investigated for pharmacologic activity.201627483734
adonis sp., convallaria sp., strophanthus sp., thevetia sp., and leonurus sp. - cardiotonic plants with known traditional use and a few preclinical and clinical studies.plants have been always a fruitful source of active metabolites against many human disorders, where cardiovascular (cv) diseases have been one of the major health problems all over the world. there are some clinically proved medicinal plants with cardioprotective effects such as crataegus monogyna and c. oxyacantha (hawthorn) from rosaceae. on the other hand, cardiac glycosides, present in a number of plant species, are well-known for their cardiotonic activity. however, we encountered such a fa ...201627748195
single-laboratory validation for the determination of flavonoids in hawthorn leaves and finished products by lc-uv.suitably validated analytical methods that can be used to quantify medicinally active phytochemicals in natural health products are required by regulators, manufacturers, and consumers. hawthorn (crataegus) is a botanical ingredient in natural health products used for the treatment of cardiovascular disorders. a method for the quantitation of vitexin-2″-o- rhamnoside, vitexin, isovitexin, rutin, and hyperoside in hawthorn leaf and flower raw materials and finished products was optimized and vali ...201627776376
antibacterial, antioxidant and anti-proliferative properties and zinc content of five south portugal herbs.crataegus monogyna l. (rosaceae) (cm), equisetum telmateia l. (equisataceae) (et), geranium purpureum vil. (geraniaceae) (gp), mentha suaveolens ehrh. (lamiaceae) (ms), and lavandula stoechas l. spp. luisieri (lamiaceae) (ls) are all medicinal.201727925492
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