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inactivation of poliovirus by formaldehyde: theoretical and practical aspects.since formaldehyde, either alone or in combination with other inactivating agents, is at present used in the production of all so-called "killed" poliovirus vaccines, a thorough knowledge of the kinetics of the reaction between the chemical agent and the virus, and of the mechanisms involved, is of great practical importance. in this paper the problem is discussed against the background of present knowledge of the structure of the virus and the chemical nature of the action of formaldehyde.195713511143
aetiologic study of poliomyelitis cases occurred in the second half of 1955 in hungary. 195713487262
growth characteristics of poliovirus in hela cells: nucleic acid metabolism.the rna and dna contents of the nucleus and cytoplasm of the hela cell were determined. the rates of incorporation of p(32) into the various nucleic acid fractions were established for the ordinary hela cell maintained under a set of standard conditions. the changes in the rates of incorporation of p(32) and in the amounts of rna and dna which occurred subsequent to infection with poliovirus were followed throughout the infectious cycle. these changes were correlated with the intracellular appea ...195713475620
[search for poliomyelitis & coxsackie viruses in the sewers of elisabethville]. 195713444992
influence of pyrimidine analogs and related compounds on the propagation of poliomyelitis virus in tissue culture. 195713429457
poliovirus precipitins; a study by means of diffusion in agar.antigens present in poliovirus concentrates react with antibodies present in the serum of hyperimmunized monkeys to give type-specific precipitates. one or more bands of precipitate can be formed wherever such homotypic reactants, diffusing into an agar gel, meet in sufficient concentration and in equivalent proportions. no qualitative differences have been detected between the type-specific reactions given by different strains of the same virus type; and no precipitates have been seen which cou ...195713475622
neonatal immunity. i. disparity in maternal-infant poliovirus antibody. 195713485099
[the poliovirus with respiratory distress]. 195713527884
properties and behavior of orally administered attenuated poliovirus vaccine. 195713438685
effective passive immunization of mice twelve days after intracerebral inoculation of type 2 poliovirus. 195713463330
spread of poliovirus infection during an epidemic of unusual severity, woodbury county iowa, and dakota county, nebraska, 1952. 195713424523
social patterns of antibody to poliovirus. 195713417596
observations on natural poliovirus infections in immunized children. 195713411317
poliomyelitis: comparison of responses of vaccinated and naturally immune humans to ingestion of attenuated poliovirus. 195713496118
inactivation of poliomyelitis virus by formaldehyde; incubation time in tissue culture of formalin treated virus. 195813545794
the effect of chlorine in water on enteric viruses. 195813583275
[behavior of glycolytic enzyme activity in tissue cultures before and after inoculation with viruses. ii. measurements in tissue cultures infected with poliomyelitis virus type i in comparison to normal tissue cultures]. 195813546200
[studies on differentiation of morphological changes in cell cultures from rhesus monkey kidneys infected with poliovirus hominis (type 1, mahoney) and echo virus (type 9, k 696)]. 195813612119
[etiological study on the poliomyelitis epidemic in hungary in 1957]. 195813613782
[kinetics of formaldehyde inactivation of viruses, with special reference to poliomyelitis virus]. 195813616609
[effects of essential fatty acids on the activity of poliomyelitis virus]. 195813629305
[age factor of the sero-immunity of poliomyelitis viruses and echo virus type 9]. 195813550833
variation in virulence of poliovirus. iii. on type iii virus by plaque method. 195813554636
[experimental research on the tissular affinity of various neurotropic viruses]. 195813556074
zone electrophoresis of type i poliomyelitis virus. 195813560461
[the distribution of poliomyelitis virus in tuscany. i. general results of etiological research]. 195813569005
[characteristics of the mk strain of poliomyelitis virus pathogenic for monkeys, cotton rats and newborn mice]. 195813569983
[a method for the visual determination of the cytopathogenic action of poliomyelitis virus on vitally stained cells]. 195813570005
effect of colchicin on poliomyelitis virus synthesis and enzyme activities of suspended rhesus kidney fragments. 195813574146
first poliovirus isolation done in hawaii; preliminary report. 195813574678
macrocrystalline patterns of closely packed poliovirus particles in ultrathin sections. 195813576580
correlation of the yield of poliovirus with the size of isolated tissue cultured cells. 195813581512
interference and multiplicity reactivation in polioviruses. 195813581529
dissociation of poliomyelitis virus from neutralizing antibody. 195813581538
observations on the excretion of type 1 poliovirus from cases and their contacts. 195813582934
[the effects of high pressures on viruses; variation with temperature of the pressure required for inactivation of poliomyelitis virus in tissue culture]. 195813583660
investigations of poliomyelitis antigens. 195813584365
specific precipitin reactions of the virus of poliomyelitis in gels. 195813584366
adsorption and maturation of poliovirus in singly and multiply infected hela cells.studies with polio-infected hela cells using cell disruption techniques during the early stages of infection have shown that: the inoculum of poliovirus adsorbed on hela cells is largely inactivated. infective virus accumulates in a monolayer sheet of cells in advance of release into the medium. the eclipse period is shorter in multiply infected cells than in those infected with a single particle.195813525575
detection of poliovirus i in monkey kidney cultures inoculated with overwhelming dose of adenovirus 4. 195813588061
stabilization of poliovirus by cystine. 195813593184
purification of poliovirus labeled with radiophosphorus. 195813593185
production of noninfectious complement-fixing poliovirus particles in hela cells treated with proflavine. 195813593187
glucose and glutamine in poliovirus production by hela cells. 195813593191
the effect of neutral red on plaque formation in two virus-cell systems. 195813593192
sparing effect of a high egg passage-fixed rabies virus on the intracerebral infection of mice with type 2 poliovirus. 195813593194
immunochemical studies of poliovirus. iii. further studies on the immunologic and physical properties of poliovirus particles produced in tissue culture. 195813598924
[titration of the s. k. new haven poliomyelitis virus strain]. 195813600035
observations on the interaction of poliovirus and host cells in vitro. i. the effect of environmental temperature. 195813607925
initial stages of the interaction of hela cells with poliovirus. 195813534311
studies of the inactivation of poliomyelitis virus by formaldehyde; inactivation of partially purified virus material and the effect upon the rate of inactivation by addition of glycine. 195813534313
the structure of crystals of purified mahoney poliovirus. 195813535719
ultracentrifugal examination of dissociated poliovirus. 195813535747
[activated, inactivated and weakened poliomyelitis virus]. 195813537660
effect of sodium bicarbonate concentration on plaque formation of virulent and attenuated polioviruses. 195813539371
immunochemical studies of poliovirus. ii. kinetics of the formation of infectious and noninfectious type 1 poliovirus in three cell strains of human derivation. 195813539385
influence of prior active immunization on the presence of poliomyelitis virus in the pharynx and stools of family contacts of patients with paralytic poliomyelitis. 195813542077
mammalian viruses and rickettsiae; their purification and recovery by cellulose anion exchange columns has significant implications.techniques of column chromatography with cellulose ion exchangers have been successfully applied to mammalian viruses and rickettsiae. recovery of virus is excellent, and appreciable purification in terms of phosphorus and protein removal has been demonstrated. elution characteristics of poliovirus (types 1, 2, and 3), and coxsackie a9 virus are similar, whereas those of echo-13 and colorado tick fever differ from them as well as from each other. elution diagrams of preparations of echo-13 and p ...195813543337
study of the mutability of d lines of polioviruses. 195813544102
studies on the induction of mutations in poliovirus by proflavin. 195813544103
size and structure of echo, poliomyelitis, and measles viruses determined by ionizing radiation and ultrafiltration. 195813544105
multiplication of poliomyelitis virus in hetero-transplanted human embryonic tissue. 195813532709
complementfixing antigens of living and inactivated poliovirus. i. complement-fixing antibody response of laboratory animals to poliovirus. 195813533408
[visualization & formaldehyde inactivation of partially purified & concentrated poliomyelitis virus]. 195813625990
[isolation and classification of 96 strains of poliomyelitis virus in the period 1956-1957]. 195813584531
[poliomyelitis in campania in 1956; incidence of the three types of poliomyelitis virus as causative agents of paralytic poliomyelitis]. 195813584528
infectivity of ribonucleic acid from poliovirus in human cell monolayers.ribonucleic acid prepared by the method of gierer and schramm from concentrated and partially purified types i and ii polioviruses has been demonstrated to be infectious for hela and human amnion cells in monolayers. in areas of cytopathogenic action resulting from invasion of cells by rna, intact poliovirus, of the type from which the rna had been prepared, is present. the infectivity of the rna was completely inactivated by a 2 minute exposure to purified ribonuclease or to whole normal monkey ...195813575680
russian coxsackie a-7 virus ab iv strain; neuropathogenicity and comparison with poliovirus. 195813563877
concerning the cytopathogenic effect of poliovirus; evidence for an extraviral toxin. 195813563872
[comparative biochemical studies on normal and poliomyelitis virus infected tissue cultures. ix. nucleolytic enzyme activity in cultures of suspended monkey kidney slices before and after inocculation with poliomyelitis virus]. 195813546186
studies of the inactivation of poliomyelitis virus by formaldehyde; the effect upon the rate of inactivation of temperature, ph and concentration of formaldehyde. 195813545795
poliovirus mutants with altered responses to cystine. 195813525651
a study of the effect of antiserum on poliovirus infection induced by the intraspinal inoculation of rhesus monkeys. 195813514079
poliovirus type 1 isolated from a budgerigar. 195813515269
metabolism of human amnion cell cultures infected with poliomyelitis virus. i. glucose metabolism during virus synthesis. 195813518183
mutation of polioviruses to resistance to neutralizing substances in normal bovine sera. 195813519748
inactivation of type 1, poliomyelitis virus with chlorine. 195813519749
infectivity of ribonucleic acid of poliovirus on hela cell mono-layers. 195813519758
a small-scale trial of type iii attenuated living poliovirus vaccine. 195813584894
infections with poliovirus types 2 and 3 in day nurseries and an orphanage. 195813497668
complement-fixing antigens of live and inactivated poliovirus. iii. evaluation of a sensitive quantitative procedure for complement fixation. 195813594931
response of pregnant women and their infants to poliomyelitis vaccine; distribution of poliovirus antibody in pregnant women before and after vaccination; transfer, persistence, and induction of antibodies in infants. 195813575112
antibodies against poliovirus in vaccinated and unvaccinated children in an epidemic area. 195813551000
poliovirus neutralizing antibody levels in pediatricians and preclinical faculty members. 195813507867
neurotoxoid interference in macacus rhesus infected intramuscularly with poliovirus. 195813529027
poliovirus studies in central scotland. 195813529049
experiences in the production of poliovirus vaccines. 195813579007
the use of 0.1 ml whole blood samples for testing neutralizing antibodies against poliovirus. 195813534321
comparative study of aerobic glycolysis by different cell strains in tissue culture. possible relation between poliomyelitis virus susceptibility and glycolytic metabolism. 195913849552
[infectiousness of ultracentrifuge components in partially purified poliomyelitis virus preparations]. 195913855729
[on the presence of high molecular desoxyribonucleic acid in partially purified concentrate of poliomyelitis virus]. 195913855730
[isolation of poliomyelitis virus in the child population of veneto in the years 1957-1958]. 195913826759
differences in stability of antigen-antibody complexes formed with poliovirus and acute and convalescent phase human sera. 195913805346
[the reaction between poliomyelitis virus and formaldehyde: a partially reversible process]. 195913830626
poliomyelitis-virus flocculation rection. behaviour of sera of cases and vaccinated individuals. 195913832165
[cytopathogenic action of poliomyelitis virus toward a cellular strain of bovine origin]. 195913842165
[characteristics of the poliomyelitis virus]. 195913816735
[commentary on material sent to the pasteur institute of paris for investigation of types of poliomyelitis virus]. 195913801274
purification and properties of poliovirus. 195913626666
[the incidence of different enteric viruses isolated during the year 1957]. 195913627581
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