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therapeutic effect of broussonetia papyrifera and lonicera japonica in ovalbumin-induced murine asthma model.broussonetia papyrifera (l.) vent. and lonicera japonica thunb. have been used in recent medicinal research for their antioxidative and anti-inflammatory properties. the present study investigated the therapeutic efficacy of b. papyrifera and l. japonica ethanolic extracts in a murine model of ovalbumin-induced asthma, in which intra-peritoneal (ip) injections and aerosol ovalbumin delivery were used to induce allergic asthma. bronchioalveolar lavage fluid (balf), serum samples, lungs and livers ...201324427953
antioxidant activities of aqueous extracts from 12 chinese edible flowers in vitro and in vivo.the antioxidant function of edible flowers have attracted increasing interest. however, information is lacking on the impact of edible flowers on oxidative injury including hypoxia-re-oxygenation and hyperlipidemia. the antioxidant activities of aqueous extracts from 12 chinese edible flowers were assessed in four different antioxidant models, including total antioxidant capacity (tac), oxygen radical absorbance capacity (orac), scavenging hydroxyl radical capacity (shrc) and scavenging superoxi ...201728326000
[a multicenter randomized controlled study on the efficacy and safety of yinzhihuang oral solution for the treatment of neonatal indirect hyperbilirubinemia in term newborn infants].a large-scale prospective multicenter randomized controlled trial was conducted to evaluate the efficacy and safety of yinzhihuang oral solution for the treatment of neonatal indirect hyperbilirubinemia in term newborn infants. yinzhihuang oral solution is a herbal extract with the main components of herba artemisiae scopariae, scutellaria, lonicera japonica and gardenia jasminoides.201122176900
[clinical observation of integrated acupuncture and herbal medicine for constipation of excess fu syndrome due to phlegm heat in acute cerebral infarction].to explore the optimal therapy for constipation of excess fu syndrome due to phlegm heat in acute cerebral infarction.201121692282
luteolin inhibited the gene expression, production and secretion of muc5ac mucin via regulation of nuclear factor kappa b signaling pathway in human airway epithelial cells.luteolin, a flavonoidal compound derived from lonicera japonica thunb. and chrysanthemum indicum l., has been reported to show anti-inflammatory, anti-oxidative and anti-carcinogenic effects. in this study, we investigated whether luteolin significantly affects the secretion, production and gene expression of airway mucin. confluent nci-h292 cells were pretreated with luteolin for 30 min and then stimulated with egf (epidermal growth factor) or pma (phorbol 12-myristate 13-acetate) for 24 h or t ...201525285988
comparison of the profiles of chlorogenic acids and their derivatives from three chinese traditional herbs by lc-msn.to investigate the chlorogenic acids resources in eucommia ulmoides olive leaves, lonicera japonica thunb. leaves and houttuynla cordata thunb. leaves, methanolic extracts of these three materials have been analysed qualitatively for chlorogenic acids and their derivatives by structure-diagnostic lc-msn. three monocaffeoylquinic acids (3-cqa, 4-cqa, 5-cqa) were detected. 5-cqa dominated this subgroup in eucommia ulmoides olive and lonicera japonica thunb. leaves, but 3-cqa and 4-cqa dominated th ...200818507347
[study of screening pseudoallergenic substances of shuanghuanglian injection].in this study, chemistry, biology and pharmacology were combinated to screen pseudoallergenic substances of shuang-huanglian injection (shli) so that to establish a scientific and systematic approach to screen pseudoallergenic substances of traditional chinese medicine injections. the mouse pseudoallergic reaction models were used to screen the pseudoallergic reaction of shli's intermediate extract and the intermediate extract's component or ingredient. among the three intermediates of shuanghua ...201526666017
exploiting genes and functional diversity of chlorogenic acid and luteolin biosyntheses in lonicera japonica and their substitutes.chlorogenic acids (cgas) and luteolin are active compounds in lonicera japonica, a plant of high medicinal value in traditional chinese medicine. this study provides a comprehensive overview of gene families involved in chlorogenic acid and luteolin biosynthesis in l. japonica, as well as its substitutes lonicera hypoglauca and lonicera macranthoides. the gene sequence feature and gene expression patterns in various tissues and buds of the species were characterized. bioinformatics analysis reve ...201423085319
anti-inflammatory activity of herbal medicines: inhibition of nitric oxide production and tumor necrosis factor-alpha secretion in an activated macrophage-like cell line.houttuynia cordata thunb. (hc), glycyrrhiza uralensis fischer (gu), forsythia suspense (thunb.) vahl (fs), and lonicera japonica thunb. (lj) are chinese herbs known to possess anti-inflammatory properties. the effects of aqueous extracts of these herbs on the production of the pro-inflammatory mediators, nitric oxide (no) and tumor necrosis factor-alpha (tnf-alpha) were examined in an activated macrophage-like cell line, raw 264.7 cells. aqueous extracts from fs at 0.0625-2.0 mg/ml inhibited in ...200516047559
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