Publications

research on the change of chemical composition in productive process of re du ning injection by hplc/q-tof ms.	a high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (hplc/q-tof ms) was developed for the analysis of chemical composition change in the production process of re du ning injection, a chinese medicine preparation with a combination of lonicera japonica thunb., gardenia jasminoides ellis and artemisia annua l. a total of 90 compounds from raw materials-intermediates-re du ning injection were detected; among them, 55 compounds were identified or tentati ...	2016	26058547
pharmacokinetics and disposition of circulating iridoids and organic acids in rats intravenously receiving reduning injection.	reduning injection, prepared from a combination of gardenia jasminoides fruits, lonicera japonica flower buds, and the artemisia annua aerial part, is extensively used for treatment of viral upper respiratory tract infections in china. iridoids, organic acids, and flavonoids are likely important compounds of the herbal injection because of their reported pharmacological properties. this study was designed to characterize pharmacokinetics and disposition of the major circulating herbal compounds ...	2016	27590023
development of a monoclonal antibody-based enzyme-linked immunosorbent assay for luteoloside detection in flos lonicerae japonicae.	flos lonicerae japonicae (flj), the flower bud of lonicera japonica thunb. (caprifoliaceae), is a widely used traditional chinese medicine with various pharmacological activities. luteoloside is a major active compound and a quality control marker of flj. luteolin-7-o-glucuronide (lg), an analog of luteoloside, was conjugated with bovine serum albumin (bsa) and ovalbumin (ova) to create the immunogen and coating antigen, respectively. a sensitive and specific monoclonal antibody (mab), designate ...	2016	26892641
in vitro study on anti-hepatitis c virus activity of spatholobus suberectus dunn.	hepatitis c virus (hcv) infects 200 million people worldwide, and 75% of hcv cases progress into chronic infections, which consequently cause cirrhosis and hepatocellular carcinoma. hcv infection is treated with currently considered standard drugs, including direct anti-viral agents (daas), alone or in combination with peginterferon-α plus ribavirin. however, sustained viral responses vary in different cohorts, and high costs limit the broad use of daas. in this study, the ethanol and water extr ...	2016	27754461
chinese vegetative materia medica in a venereological treatise by jean astruc from 1740.	historical medical sources can be still queried for forgotten cures and remedies. traditional chinese medicine has dealt with lues venerea (syphilis) since the five dynasties period (10th century). chinese indigenous materia medica and remedies recorded, studied or imported by the europeans can reveal known or quite unknown medicinal plants. the studied jean astruc's work is a published ethnopharmacological survey carried out in beijing in the 1730s and it deserves a modern interpretation.	2016	27132716
honeysuckle aqueous extract and induced let-7a suppress dengue virus type 2 replication and pathogenesis.	honeysuckle (lonicera japonica thunb.), a traditional chinese herb, has widely been used to treat pathogen infection. however, the underlying-mechanism remains elusive.	2017	28052239
agrimonia pilosa ledeb., cinnamomum cassia blume, and lonicera japonica thunb. protect against cognitive dysfunction and energy and glucose dysregulation by reducing neuroinflammation and hippocampal insulin resistance in β-amyloid-infused rats.	the water extracts of cinnamomum cassia blume bark (ccb; lauraceae), lonicera japonica thunb. flower (ljt; caprifoliaceae), and agrimonia pilosa ledeb. leaves (apl; rosaceae) prevented amyloid-β (25-35)-induced cell death in pc12 cells in our preliminary study. we evaluated whether long-term oral consumption of ccb, ljt, and apl improves cognitive dysfunction and glucose homeostasis in rats with experimentally induced ad-type dementia.	2017	26842885
on-line quantitative monitoring of liquid-liquid extraction of lonicera japonica and artemisia annua using near-infrared spectroscopy and chemometrics.	liquid-liquid extraction of lonicera japonica and artemisia annua (jq) plays a significant role in manufacturing reduning injection. many process parameters may influence liquid-liquid extraction and cause fluctuations in product quality.	2017	26246744
antioxidant activities of aqueous extracts from 12 chinese edible flowers in vitro and in vivo.	the antioxidant function of edible flowers have attracted increasing interest. however, information is lacking on the impact of edible flowers on oxidative injury including hypoxia-re-oxygenation and hyperlipidemia. the antioxidant activities of aqueous extracts from 12 chinese edible flowers were assessed in four different antioxidant models, including total antioxidant capacity (tac), oxygen radical absorbance capacity (orac), scavenging hydroxyl radical capacity (shrc) and scavenging superoxi ...	2017	28326000