Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| [clinical and experimental study of xiao er ke cuan ling oral liquid in the treatment of infantile bronchopneumonia]. | xiao er ke chuan ling oral liquid (kcl) is a chinese herbal preparation consisted of 10 herbs such as prunus armeniacae, scutelaria baicalensis, lonicera japonica etc. 30 children suffering from bronchopneumonia and/or acute bronchitis were treated with kcl (treated group) and another 30 cases were treated with penicillin and aminophylline (control group). results: cure rate and effective rate in treated group was 26.6%, and 93.3% respectively. while in control group was 30% and 96.6% respective ... | 1992 | 1304839 |
| inhibition of platelet activation and endothelial cell injury by polyphenolic compounds isolated from lonicera japonica thunb. | effects of the polyphenolic compounds isolated from lonicera japonica thunb on platelet aggregation, platelet thromboxane biosynthesis and hydrogen peroxide-induced endothelial cell injury were studied. with regard to the inhibitory effect on human platelet aggregation, methyl caffeate, 3,4-di-o-caffeoylquinic acid and methyl 3,4-di-o-caffeoylquinate had a strong effect. they significantly inhibited the second wave of platelet aggregation induced by adp. concerning thromboxane biosynthesis trigg ... | 1992 | 1603820 |
| [clinical and experimental study of the effect of kang er xin-i on viral myocarditis]. | kang er xin-i (kex-i) is a proved recipe used to treat viral myocarditis. it consists of lonicera japonica, ophiopogon japonicus, astragalus membranaceus mainly and possesses the effect of clearing away heat and toxic materials and supplementing the vital energy and nourishing. the clinical study was carried out with kex-i according to a random, paired and cross-over design. coenzyme q10 was used as a control and left ventricular function was observed. the result showed: after being treated with ... | 1991 | 1659497 |
| [the combined modulating effects of cerium nitrate with certain chinese traditional drugs on altered cell-mediated immunities in scald mice]. | altered cell-mediated immunities (cmi) is one of the important causes of increased susceptibility to infection and, high mortality of burned patients. this paper presents the experimental work on mice with scald injury to restore their altered cmi by local application of cerium nitrate (ce) or systemic administration of astragalus membranaceus (am) or lonicera japonica thunb (ljt), as well as combination use of these drugs. the proliferative response to con a and the ability of il-2 production o ... | 1990 | 2086133 |
| studies on the saponins of lonicera japonica thunb. | 1988 | 3246039 | |
| inactivation of phospholipase a2 by naturally occurring biflavonoid, ochnaflavone. | ochnaflavone, a medicinal herb product isolated from lonicera japonica, strongly inhibited rat platelet phospholipase a2 (ic50, about 3 microm). inactivation was concentration and ph dependent (maximum inactivation occurred between ph 9.0 and 10.0). ochnaflavone inhibited the enzyme by a noncompetitive manner, with the apparent ki value of 3 x 10(-5) m. reversibility was studied directly by dialysis method; the inhibition was irreversible. in addition, the inhibitory activity of ochnaflavone is ... | 1994 | 7999121 |
| the quest for a herbal contraceptive. | an oral herbal contraceptive would allow couples control their fertility without consulting a health worker, which in turn would likely markedly increase the number of couples practicing family planning. other advantages of such a contraceptive would include the familiarity rural people have with herbal medicines, the fewer side effects associated with herbal preparations, their ready availability from local sources, and protection of privacy. there are many references to plants in india with ... | 1993 | 8241931 |
| differential inhibition of reverse transcriptase and cellular dna polymerase-alpha activities by lignans isolated from chinese herbs, phyllanthus myrtifolius moon, and tannins from lonicera japonica thunb and castanopsis hystrix. | two lignans, phyllamycin b and retrojusticidin b isolated from phyllanthus myrtifolius moon have been demonstrated to have a strong inhibitory effect on human immunodeficiency virus-1 reverse transcriptase activity (hiv-1 rt), but much less inhibitory effect on human dna polymerase-alpha (hdnap-alpha) activity. fifty percent inhibitory concentrations of phyllamycin b and retrojusticidin b were determined to be 3.5 and 5.5 microm for hiv-1 rt, and 289 and 989 microm for hdnap-alpha, respectively. ... | 1995 | 8540756 |
| anti-inflammatory effect of the aqueous extract from lonicera japonica flower is related to inhibition of nf-kappab activation through reducing i-kappabalpha degradation in rat liver. | we investigated the anti-inflammatory effects of aqueous extract from lonicera japonica flower (aelj), a traditional skin rash drug, in lipopolysaccharide (lps)-induced rat liver sepsis. immunoblot analysis showed that the level of nuclear factor (nf)-kappabp65 was rapidly up-regulated and inhibitory (i)-kappabalpha was down-regulated by lps challenge. however, aelj inhibited the increase of nf-kappabp65 and degradation of i-kappabalpha in the liver of lps-challenged rats. immunohistochemical an ... | 2001 | 11115613 |
| loniceroside c, an antiinflammatory saponin from lonicera japonica. | a new triterpenoid saponin, loniceroside c was isolated from the aerial parts of lonicera japonica. its structure was established to be 3-o-beta-d-glucopyranosyl hederagenin 28-o-alpha-l-rhamnopyranosyl (1-->2)-[beta-d-xylopyranosyl(1-->6)]-beta-d-glucopyranosyl ester by spectroscopic techniques and chemical transformations. loniceroside c showed in vivo antiinflammatory activity against mouse ear edema provoked by croton oil. | 2003 | 12612424 |
| anti-inflammatory effect of lonicera japonica in proteinase-activated receptor 2-mediated paw edema. | lonicera japonica (caprifoliaceae) has long been used for treatment of infectious diseases. in the present study, the anti-inflammatory effects of l. japonica water extract (aelj) were investigated in proteinase-activated receptor 2 (par2)-mediated mouse paw edema. | 2003 | 12636936 |
| interaction between warfarin and the herbal product quilinggao. | to describe a patient with loss of anticoagulation control and bleeding after consumption of the combination herbal product quilinggao. | 2003 | 12773074 |
| [comparative study on content of chlorogenic acid in lonicera japonica and l. macranthoides]. | to exploit and utilize reasonably the abundant natural resources by appraising the medicinal purposes of lonicera macranthoides hands-mazz. through the content of the useful chemical constitutents chlorogenic acid. | 2003 | 14528678 |
| inhibitory effect of luteolin on tnf-alpha-induced il-8 production in human colon epithelial cells. | interleukin (il)-8 plays a central role in the initiation and maintenance of inflammatory responses in the inflammatory bowel disease. the proinflammatory cytokine-mediated production of il-8 requires activation of various kinases, which leads to the ikappab degradation and nf-kappab activation. in this study, we investigated the role of luteolin, a major flavonoid of lonicera japonica, on tnf-alpha-induced il-8 production in human colonic epithelial cells. ht29 cells were stimulated with tnf-al ... | 2005 | 15589482 |
| luteolin induced dna damage leading to human lung squamous carcinoma ch27 cell apoptosis. | luteolin is an active compound from the lonicera japonica (caprifoliaceae). luteolin (50 microm)-induced human lung carcinoma ch27 cell apoptosis is a typical apoptosis that was accompanied by a significant dna condensation and apoptotic body formation. luteolin-induced apoptosis is related to its ability to change the expression of apoptotic markers, such as caspase-3 (caspase-dependent) and apoptosis-inducing factor (caspase-independent) protein expression. the alkaline microgel electrophoresi ... | 2005 | 15680256 |
| [study on qualitative and quantitative methods for yinhuang liangxiao granule]. | to establish the quality standard of yinhuang langxiao granule. | 2004 | 15706894 |
| anti-inflammatory activity of herbal medicines: inhibition of nitric oxide production and tumor necrosis factor-alpha secretion in an activated macrophage-like cell line. | houttuynia cordata thunb. (hc), glycyrrhiza uralensis fischer (gu), forsythia suspense (thunb.) vahl (fs), and lonicera japonica thunb. (lj) are chinese herbs known to possess anti-inflammatory properties. the effects of aqueous extracts of these herbs on the production of the pro-inflammatory mediators, nitric oxide (no) and tumor necrosis factor-alpha (tnf-alpha) were examined in an activated macrophage-like cell line, raw 264.7 cells. aqueous extracts from fs at 0.0625-2.0 mg/ml inhibited in ... | 2005 | 16047559 |
| [karyotype analysis of lonicera japonica and l. maackii]. | to study lonicera japonica thunb. and lonicera maackii (rupr. ) maxim. chromosome number, karyotype, volume. | 2005 | 16107023 |
| parental use of the term "hot qi" to describe symptoms in their children in hong kong: a cross sectional survey "hot qi" in children. | the chinese term "hot qi" is often used by parents to describe symptoms in their children. the current study was carried out to estimate the prevalence of using the chinese term "hot qi" to describe symptoms in children by their parents and the symptomatology of "hot qi". | 2006 | 16393344 |
| antioxidant enzymes activity involvement in luteolin-induced human lung squamous carcinoma ch27 cell apoptosis. | luteolin (3',4',5,7-tetrahydroxyflavone) is an active constituent of lonicera japonica (caprifoliaceae), and has been reported to produce anti-tumor activities. however, the apoptosis-inducing activity of luteolin still remains unknown. flavonoids have been found to possess prooxidant and antioxidant action. the biological and pharmacological effect of flavonoid may depend upon its behavior as either an antioxidant or a prooxidant. our experiments found that luteolin-induced ch27 cell apoptosis ... | 2006 | 16469309 |
| the naturally occurring biflavonoid, ochnaflavone, inhibits lps-induced inos expression, which is mediated by erk1/2 via nf-kappab regulation, in raw264.7 cells. | ochnaflavone (oc), a naturally occurring biflavonoid with anti-inflammatory activity [s.j. lee, j.h. choi, h.w. chang, s.s. kang, h.p. kim. life sci. 57(6), 1995, 551-558], was isolated from lonicera japonica and its effects on inducible nitric oxide synthase (inos) gene expression was examined in raw264.7 cells. u0126, an inhibitor of the extracellular signal-regulated kinase (erk), significantly down-regulated lipopolysaccharide (lps)-induced inos expression and promoter activity. transactivat ... | 2006 | 16527246 |
| the effect of medicinal plants used in chinese folk medicine on rantes secretion by virus-infected human epithelial cells. | the accumulation of inflammatory cells in the infective sites has been reported to play a crucial role in the progression of chronic inflammation and multiple sclerosis after viral infection. in the present study, nine ethanol extracts of forsythia suspensa vahl. (oleaceae), lonicera japonica thunb. (caprifoliaceae), isatis indigotica fort. (cruciferae), strobilanthes cusia (ness.) o. kuntze (acanthaceae), astragalus membranaceus (fisch.) bge. (leguminosae), hedysarum polybotrys hand.-mazz. (leg ... | 2006 | 16621378 |
| naturally occurring biflavonoid, ochnaflavone, inhibits cyclooxygenases-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells. | ochnaflavone is a medicinal herbal product isolated from lonicera japonica that inhibits cyclooxygenase-2 (cox-2) dependent phases of prostaglandin d2 (pgd2) generation in bone marrow-derived mast cells (bmmc) in a concentration-dependent manner with ic50 values of 0.6 microm. western blotting probed with specific anti-cox-2 antibodies showed that the decrease in quantity of the pgd2 product was accompanied by a decrease in the cox-2 protein level. in addition, this compound consistently inhibit ... | 2006 | 16681032 |
| acute and subacute toxicity study of the ethanol extract from lonicera japonica thunb. | the ethanol extract from the leaves of lonicera japonica thunb. was evaluated for acute and subacute toxicity. the single oral dose of the ethanol extract at 5,000 mg/kg did not produce mortality or significant changes in the general behaviour and gross appearance of the internal organs of rats. in subacute toxicity study, the ethanol extract was administered orally at a dose of 1,000 mg/kg/day for a period of 14 days. the satellite group was treated with the ethanol extract at the same dose and ... | 2006 | 16697541 |
| ochnaflavone inhibits tnf-alpha-induced human vsmc proliferation via regulation of cell cycle, erk1/2, and mmp-9. | ochnaflavone (c-3 of apigenin-0-c-4 of apigenin; oc), a biflavonoid present in the human diet, is known to inhibit angiotensin ii-induced hypertrophy and serum-induced smooth muscle cell proliferation. oc is known to have anti-fungal and anti-inflammatory activities. however, it is not known whether oc exerts similar cardioprotective effects in cells treated with tumor necrosis factor (tnf)-alpha. in this study, we isolated oc from lonicera japonica and studied its effect on matrix metalloprotei ... | 2006 | 16795041 |
| antioxidant constituents and a new triterpenoid glycoside from flos lonicerae. | as a component of our continuing investigations into herb-derived antioxidant agents, we have evaluated the antioxidant effects of flos lonicerae (lonicera japonica flowers), via 1,1-diphenyl-2-picrylhydrazyl (dpph) radical, total reactive oxygen species (ros), hydroxyl radical (*oh), and peroxynitrite (onoo-) assays. among the methanolic extract and the dichloromethane, ethyl acetate, n-butanol, and water fractions, the etoac fraction of flos lonicerae exhibited marked scavenging/inhibitory act ... | 2007 | 17328234 |
| [relative adscriptions of components in the effective fractions of yinqiao decoction and its composing individual herbs]. | hplc and lc-ms/ms were used to establish a comprehensive hplc analytical method of yinqiao decoction and identify the chemical constituents of the whole and individual herbs of yinqiao decoction. ywg-c18 (250 mm x4. 6 mm id, 10 microm) column was used; the mobile phase was composed of acetonitrile (a) and water ( b, with 3% acetic acid) with gradient elution; the flow rate was 1. 0 ml x min(-1) and the column temperature was set up at 25 degrees c. the detection wavelength was 280 nm. the chroma ... | 2007 | 17518050 |
| a rapid rp-hptlc densitometry method for simultaneous determination of major flavonoids in important medicinal plants. | a simple, sensitive, selective, precise, and robust high-performance tlc (hptlc) method was developed and validated for determination of flavonoids in herbal extracts bauhinia variegata, bacopa monnieri, centella asiatica, ginkgo biloba, lonicera japonica, rosa bourboniana, rosa brunonii, and rosa damascena. the hptlc of flavonoids was performed on rp-18 f(254) tlc plates with dual run, water (5% formic acid)/methanol (70:30) and water (5% formic acid)/methanol (50:50) as mobile phases. densitom ... | 2007 | 17654615 |
| binding study of flos lonicerae japonicae with bovine serum albumin using centrifugal ultrafiltration and liquid chromatography. | the screening and analysis of bioactive components in traditional chinese medicines (tcms) is very important not only for the quality control of chinese herbs but also for elucidating the therapeutic principles. this study developed a new method for screening and analyzing bioactive compounds from tcms using centrifugal ultrafiltration coupled with high-performance liquid chromatography. the method was successfully applied in the binding study of flos lonicerae japonicae with bovine serum albumi ... | 2008 | 18004737 |
| pyridinium alkaloid-coupled secoiridoids from the flower buds of lonicera japonica. | three pyridinium inner salt alkaloids, lonijaposides a-c (1-3), based on an unprecedented skeleton of an n-substituted nicotinic acid nucleus coupled through c-5 with c-7 of a secoiridoid, together with seven known iridoids, have been isolated from the flower buds of lonicera japonica. their structures were elucidated by spectroscopic and chemical analyses. lonijaposide c (3) showed activity against the release of glucuronidase in rat polymorphonuclear leukocytes induced by the platelet-activati ... | 2008 | 18321056 |
| anti-angiogenic, antinociceptive and anti-inflammatory activities of lonicera japonica extract. | this study aimed to elucidate some novel pharmacological activities of lonicera japonica (caprifoliaceae), which is widely used in oriental folk medicine. the ethanolic extract of l. japonica (lj) dose dependently inhibited chick chorioallantoic membrane angiogenesis. the antinociceptive activity of lj was assessed using the acetic acid-induced constriction model in mice. lj showed anti-inflammatory activity in two in-vivo models: the vascular permeability and air pouch models. lj suppressed the ... | 2008 | 18498715 |
| comparison of the profiles of chlorogenic acids and their derivatives from three chinese traditional herbs by lc-msn. | to investigate the chlorogenic acids resources in eucommia ulmoides olive leaves, lonicera japonica thunb. leaves and houttuynla cordata thunb. leaves, methanolic extracts of these three materials have been analysed qualitatively for chlorogenic acids and their derivatives by structure-diagnostic lc-msn. three monocaffeoylquinic acids (3-cqa, 4-cqa, 5-cqa) were detected. 5-cqa dominated this subgroup in eucommia ulmoides olive and lonicera japonica thunb. leaves, but 3-cqa and 4-cqa dominated th ... | 2008 | 18507347 |
| the begomoviruses honeysuckle yellow vein mosaic virus and tobacco leaf curl japan virus with dnabeta satellites cause yellow dwarf disease of tomato. | the complete nucleotide sequences of two begomoviruses (nara virus-1 and nara virus-2), a satellite dna (dnabeta-nara) and defective dnas were obtained from honeysuckle (lonicera japonica) showing characteristic yellow vein mosaic symptoms in nara prefecture, japan. one begomovirus (ibaraki virus) and a satellite dna (dnabeta-ibaraki) was isolated and cloned from honeysuckle plants exhibited typical yellowing of veins and small elliptical shaped enations along veins on the under side of the leav ... | 2008 | 18722488 |
| traditional chinese medicine for atopic eczema: pentaherbs formula suppresses inflammatory mediators release from mast cells. | pentaherbs formula (phf) containing cortex moutan, root bark of paeonia suffruticosa andr. (ranunculaceae), cortex phellodendri, bark of phellodendron chinensis schneid. (rutaceae), flos lonicerae, flower of lonicera japonica thunb. (capri-foliaceae), herba menthae, aerial part of mentha haplocalyx briq. (labiatae) and rhizoma atractylodis, rhizome of atractylodes lancea (thunb.) dc. (compositae) at the ratio of 2:2:2:1:2 was useful in the management of eczema. | 2008 | 18725279 |
| p38-associated pathway involvement in apoptosis induced by photodynamic therapy with lonicera japonica in human lung squamous carcinoma ch27 cells. | photodynamic therapy (pdt) is an effective therapy for local malignant tumors. lonicera japonica was found to have the anti-tumor effect. the aim of this study is to explore the mechanisms of apoptosis induced by pdt in lung ch27 carcinoma cells with alcohol extract from lonicera japonica as photosensitizer. our study indicated that lonicera japonica extracts exhibited significant photocytotoxicity in ch27 cells at a concentration range of 50-150 microg/ml, with 0.4-1.2j/cm2 light dose. pdt with ... | 2008 | 18796326 |
| the structure and absolute configuration of shuangkangsu: a novel natural cyclic peroxide from lonicera japonica (thunb.). | a novel cyclic peroxide, shuangkangsu (1), has been obtained from the water extract of the buds of lonicera japonica (thunb.). the structure was elucidated as 5,8-divinyl-1,4-dihydro-1,4-di-o-beta-d-glucopyranosyl-2,3-dioxane (1) on the basis of the spectral data. its absolute stereochemistry was determined to be (1s, 4s) by comparison of its cd curves with those of its optically pure analogs 2 and 3, which were synthesized from the phthalaldehyde. the absolute configurations of 2 and 3 were det ... | 2008 | 18985497 |
| determination of sweroside in rat plasma and bile for oral bioavailability and hepatobiliary excretion. | sweroside is an active ingredient of iridoid glycoside isolated from the flower buds of lonicera japonica thunb. a quantitative hplc-uv method was developed for monitoring sweroside in rat plasma, urine, feces and bile. the method was successfully applied for a basic pharmacokinetic study. the obtained data of pharmacokinetics were applied to evaluate the oral bioavailabilities of sweroside and the active ingredients of purified herbal extracts (iges-1). the absolute bioavailability was estimate ... | 2009 | 19122321 |
| phenotypical differences among b. cinerea isolates from ornamental plants. | b. cinerea is a common pathogenic fungus which causes botrytis blight (grey mould) in most ornamental plants. it may be responsible for serious preharvest diseases and postharvest losses in fruits, vegetables and flowers. in this work, several b. cinerea isolates from ornamental plants (chamelaucium uncinatum, pelargonium x hortorum, euphorbia pulcherrima, lantana camara, lonicera japonica, hydrangea macrophylla, and cyclamen persicum) affected by botrytis blight in the south of spain were studi ... | 2008 | 19226749 |
| rutin from lonicera japonica inhibits myocardial ischemia/reperfusion-induced apoptosis in vivo and protects h9c2 cells against hydrogen peroxide-mediated injury via erk1/2 and pi3k/akt signals in vitro. | we investigated pharmacological effects of rutin isolated form lonicera japonica on h2o2-induced cell death in h9c2 cells in vitro and rat myocardial ischemia-reperfusion injury model in vivo. western blot analysis showed that h2o2 increased expression of cleaved form of caspase-3 and proapoptotic bax protein, but decreased antiapoptotic bcl-2 protein in h9c2 cell. however, treatment with rutin decreased expression of both cleaved from of caspase-3 and increased bcl-2/bax ratio in h9c2 cells. th ... | 2009 | 19362115 |
| accumulation and tolerance characteristics of cadmium in a potential hyperaccumulator--lonicera japonica thunb. | phytoremediation using hyperaccumulators is a promising technique of removing soil pollutants. in the study, growth responses, cadmium (cd) accumulation capability and physiological mechanisms of lonicera japonica thunb. under cd stress were investigated. exposed to 5 and 10 mg l(-1) cd, the plants did not show any visual symptoms, furthermore, the height, dry biomass of leaves, roots and total and the chlorophyll (chl) content were obtained different grade increase. when the concentration of cd ... | 2009 | 19380199 |
| attraction of new zealand flower thrips, thrips obscuratus, to cis-jasmone, a volatile identified from japanese honeysuckle flowers. | this work was undertaken to identify floral compound(s) produced by honeysuckle flowers, lonicera japonica (thunberg), that mediate the attraction of new zealand flower thrips thrips obscuratus (crawford). volatiles were collected during the day and night and analyzed by gas chromatography-mass spectrometry (gc-ms) to determine their emission over these two periods. nine compounds were identified in the headspace; the main compound was linalool, and the other compounds were germacrene d, e,e-alp ... | 2009 | 19444522 |
| [research on medical speciality of traditional chinese medicines using dot-immunoblotting method based on polyclonal antibody prepared from traditional chinese medicines with hot/cold nature]. | to research on the substantial foundation of the medical speciality of chinese traditional medicines from immunogenicity. | 2009 | 19459307 |
| temperature-dependent growth of botrytis cinerea isolates from potted plants. | botrytis cinereo is a common aggressive saprophyte fungus which also invades injured plant tissues, causing botrytis blight (grey mould) in many ornamental plants, including potted flowering plants. several b. cinerea isolates from potted plants (pelargonium x hortorum, lantana camara, lonicera japonica, hydrangea macrophylla, and cyclamen persicum) affected by botrytis blight in the south of spain were studied and identified by pcr. the isolates showed phenotypic differences between them, as pr ... | 2009 | 20222557 |
| metabonomics study of the protective effects of lonicera japonica extract on acute liver injury in dimethylnitrosamine treated rats. | a metabonomics approach, consisting of gas chromatography coupled to mass spectrometry (gc/ms) and a multivariate statistical technique, was developed to estimate the protective effects of lonicera japonica extract (lje) on acute liver injury. a high dose of dimethylnitrosamine (dmn) was used to induce an acute stage of hepatic injury in 21 male wistar rats. the rats were divided into three groups: normal, model and treatment. pathological changes, particularly fibrosis, were also examined by az ... | 2010 | 20371156 |
| spatiotemporal dynamics of lianas during 50 years of succession to temperate forest. | although they are important components of forest communities, the general ecology and spatiotemporal patterns of temperate lianas during forest regeneration are largely unknown. the dependence of lianas on other plants for physical support makes them a potentially important driver of community dynamics. we examined 50 years of vegetation data from an old-field succession study to determine the dynamics and community controls on liana expansion within the piedmont region of new jersey, usa. four ... | 2010 | 20426327 |
| new alternatives to cosmetics preservation. | in recent years, there is a considerable interest in the development of preservative-free or self-preserving cosmetics. the aim of our work was to develop new cosmetic formulations by replacing chemical preservatives with ingredients with antimicrobial properties that are not legislated as preservatives according to annex vi of commission directive 76/768/eec. this paper describes the preservative efficacy of the well-known antimicrobial extracts of lonicera caprifoleum and lonicera japonica in ... | 2010 | 20447363 |
| cloning and characterization of a cdna coding a hydroxycinnamoyl-coa quinate hydroxycinnamoyl transferase involved in chlorogenic acid biosynthesis in lonicera japonica. | the flower buds of lonicera japonica are widely used in chinese medicine for their anti-inflammatory properties. the reason why l. japonica has potent and significant effects is that it contains various active components, especially chlorogenic acid (cga). in the present study, we isolated a hydroxycinnamoyl-coa quinate hydroxycinnamoyl transferase (hqt) gene encoding a protein of 439 amino acids from l. japonica. the rt-pcr results showed that tissue distribution of hqt was in accordance with t ... | 2010 | 20539970 |
| protective effects of luteolin against lipopolysaccharide-induced acute lung injury involves inhibition of mek/erk and pi3k/akt pathways in neutrophils. | to investigate whether luteolin, the major polyphenolic components of lonicera japonica, has beneficial effects against lipopolysaccharide (lps)-induced acute lung injury (ali) and to determine whether the protective mechanism involves anti-inflammatory effects on neutrophils. | 2010 | 20562902 |
| growth and landscape performance of ten herbaceous species in response to saline water irrigation. | ten herbaceous perennials and groundcovers were grown in raised beds from june to september in a dry, hot desert environment and micro-spray drip irrigated with synthesized saline solutions at electrical conductivity of 0.8 (tap water), 3.2, or 5.4 ds/m. plant height and two perpendicular widths were recorded monthly to calculate the growth index. landscape performance was assessed monthly by visual scores. salinity did not affect the visual scores in achillea millefolium l., gaillardia aristata ... | 2007 | 20585473 |
| the analgesic and anti-inflammatory effect of win-34b, a new herbal formula for osteoarthritis composed of lonicera japonica thunb and anemarrhena asphodeloides bunge in vivo. | lonicera japonica thunb and anemarrhena asphodeloides bunge have been used for the treatment of a variety of inflammatory diseases, cold and infective diseases in many countries, including korea and china. | 2010 | 20643199 |
| anti-inflammatory and analgesic activities of sklji, a highly purified and injectable herbal extract of lonicera japonica. | the parenteral route has many merits over the oral route, including greater predictability, reproducibility of absorption, and rapid drug action, but injectable phytomedicines are uncommon due to protein precipitating tannin and hemolytic saponin components. in this study, in an effort to develop a safe injectable analgesic phytomedicine, we prepared a tannin and saponin-free lonicera japonica extract, sklji, through fractionation and column purification, and evaluated its anti-inflammatory and ... | 2010 | 20944425 |
| luteolin ameliorates experimental lung fibrosis both in vivo and in vitro: implications for therapy of lung fibrosis. | lonicera japonica (caprifoliaceae) has been known as an anti-inflammatory herb in traditional chinese medicine for thousands of years and is used constantly for upper respiratory tract infections. luteolin, an active flavonoid compound isolated from lonicera japonica, has a spectrum of biological activities, especially with antioxidative and anti-inflammatory properties. however, whether luteolin has a direct inhibitory effect on lung fibrosis has not been established. in this study, we examined ... | 2010 | 20958047 |
| the neuroprotective effects of lonicera japonica thunb. against hydrogen peroxide-induced apoptosis via phosphorylation of mapks and pi3k/akt in sh-sy5y cells. | we investigated the neuroprotective effects of lonicera japonica thunb. (caprifoliaceae) (lj) extract against hydrogen peroxide (h(2)o(2)), a toxin created by oxidative stress and implicated in neurodegenerative diseases, in human sh-sy5y neuroblastoma cells. we examined the effects of lj against h(2)o(2)-induced cytotoxicity, apoptosis, the production of reactive oxygen species (ros), the proteolysis of cleaved poly-adp-ribose polymerase (parp), and the expression of bcl-2, bcl-xl, and cleaved ... | 2011 | 21237235 |
| [anti-erosion effect of hedgerows in hillside croplands of danjiangkou based on the evaluation with water erosion prediction project (wepp) model]. | based on the data of field experiments on the hillside croplands of danjiangkou, hubei province of china, the input files of crop characters, management measures, slope gradient and length, and soil properties for running wepp model (hillslope version) were established. combining with the local weather data, a simulation study with the model was made on the runoff and soil loss of the croplands protected by four kinds of hedgerows (amorpha fruticosa, lonicera japonica, hemerocallis fulva, and po ... | 2010 | 21265164 |
| agroinoculation of nicotiana benthamiana with cloned honeysuckle yellow vein virus isolated from lonicera japonica. | a new honeysuckle yellow vein geminivirus (hyvv) isolate (2,763 nucleotides) and the hyvv-β satellite (1,227 nucleotides) from korea were cloned and characterized from symptomatic leaves of lonicera japonica with a yellow net mosaic appearance. phylogenetic analysis of hyvv and 13 other begomoviruses revealed that hyvv has the highest nucleotide sequence homology to hyvv-uk2. grafting challenge of a virus-free l. japonica (scion) on an hyvv-infected l. japonica (stock) resulted in the appearance ... | 2011 | 21279729 |
| rottlerin inhibits lonicera japonica-induced photokilling in human lung cancer cells through cytoskeleton-related signaling cascade. | this study demonstrated that many apoptotic signaling pathways, such as rho family, pkc family, map kinase family, and mitochondria-mediated apoptotic pathway, were triggered by lonicera japonica extracts and irradiation in ch27 cells. rottlerin, a pkcd -selective inhibitor, reversed the photoactivated lonicera japonica extract-induced decrease in pkcd protein expression and change in cell morphology in this study. in addition, rottlerin inhibited the photoactivated lonicera japonica-induced dec ... | 2011 | 21331326 |
| effects of paclobutrazol on botrytis cinerea isolates obtained from potted plants. | the growth of different isolates of botrytis cinerea, collected from potted plants affected by botrytis blight in southern spain during recent years, was studied. these isolates, which show wide phenotypic differences when grown in vitro, are differentially affected by growth temperature, gibberellic acid, and paclobutrazol--an efficient plant growth retardant used widely in nursery potted plants to reduce plant size, favouring compactness, a more intense green foliage and increased stress toler ... | 2010 | 21534481 |
| [clinical observation of integrated acupuncture and herbal medicine for constipation of excess fu syndrome due to phlegm heat in acute cerebral infarction]. | to explore the optimal therapy for constipation of excess fu syndrome due to phlegm heat in acute cerebral infarction. | 2011 | 21692282 |
| gastroprotective and safety effects of win-34b, a novel treatment for osteoarthritis, compared to nsaids. | ethnopharmacological relevance: the dried flowers of lonicera japonica, also known as japanese honeysuckle, and the dried root of anemarrhena asphodeloides, the component herbs of win-34b, are traditionally used in eastern medicine to treat various inflammatory conditions including arthritis. objective: to study the acute and chronic toxicities of win-34b and to compare its effects on gastric mucosa with those of diclofenac, a widely used nsaid, and celecoxib, a selective cox-2 inhibitor. materi ... | 2011 | 21782922 |
| allergy-preventive effects of chlorogenic acid and iridoid derivatives from flower buds of lonicera japonica. | allergy-preventive activity of flower buds of lonicera japonica thunb. was found in the 35% etoh extract (lj) using an in vivo assay, the assay system uses monitoring of a decrease in blood flow (bf) in the tail vein of mice subjected to sensitization with hen-egg white lysozyme (hel). bioassay-guided fractionation of the 35% etoh extract led to isolation of chlorogenic acid (1) and three known iridoid derivatives, loganin (2), secoxyloganin (3) and sweroside (4), all of which inhibited the bf d ... | 2011 | 21804227 |
| [screen anti-influenza virus serum marker of lonicera japonica by proteomics technology]. | the candidate anti-influenza virus serum marker of lonicera japonica was searched by comparing the serum protein discrepancy of experimental groups. it will provide the basis for setting forth the action and mechanism of anti-influenza virus. | 2011 | 21809588 |
| homosecoiridoids from the flower buds of lonicera japonica. | homosecoiridoids (1-15) were isolated from the flower buds of lonicera japonica. compounds 1-4, designated as loniphenyruviridosides a-d, possess unprecedented skeletons featuring phenylpyruvic acid derived moieties coupled with an iridoid or a secoiridoid nucleus. compounds 5-15 (lonijaposides d-n) are additional examples of the unusual pyridinium alkaloid-coupled secoiridoids (lonijaposides a-c). the validity of the cd data to determine the configuration of the secoiridoid derivatives is discu ... | 2011 | 21942812 |
| [a multicenter randomized controlled study on the efficacy and safety of yinzhihuang oral solution for the treatment of neonatal indirect hyperbilirubinemia in term newborn infants]. | a large-scale prospective multicenter randomized controlled trial was conducted to evaluate the efficacy and safety of yinzhihuang oral solution for the treatment of neonatal indirect hyperbilirubinemia in term newborn infants. yinzhihuang oral solution is a herbal extract with the main components of herba artemisiae scopariae, scutellaria, lonicera japonica and gardenia jasminoides. | 2011 | 22176900 |
| effects of jin-ying-tang on staphylococcus aureus-induced mastitis in rabbit. | the present study was performed to investigate the effects of jin-ying-tang (jyt), a chinese herbal formula containing lonicera japonica, herba taraxaci, fructus trichosanthis, fructus forsythia, radix et rhizoma rhei, astragalus membranaceus, angelica sinensis, on rabbit mastitis induced by staphylococcus aureus. suckling rabbits were challenged with 1.5 × 10(7) colony forming unit (cfu) of s. aureus at the base of the third pair teats, and they were treated and pretreated with jyt to detect th ... | 2012 | 22303901 |
| effects of indole-3-acetic acid on botrytis cinerea isolates obtained from potted plants. | we study the growth of different isolates of botrytis cinerea collected from potted plants which were affected by botrytis blight in southern spain during recent years. these isolates, which show widely phenotypic differences when grown in vitro, are differentially affected by growth temperature, gibberellic acid applications and paclobutrazol, an efficient plant growth retardant and fungicide at the same time. in this work, we have evaluated the effect of the auxin indole-3-acetic acid (iaa) do ... | 2011 | 22702183 |
| molecular docking, kinetics study, and structure-activity relationship analysis of quercetin and its analogous as helicobacter pylori urease inhibitors. | it was disclosed in our group for the first time that the flavonoids in lonicera japonica thunb. are related to its therapy for gastric ulcer. based on this finding, 20 flavonoids were selected for helicobacter pylori urease inhibitory activity evaluation, and quercetin showed excellent potency with ic(50) of 11.2 ± 0.9 μm. structure-activity relationship analysis revealed that removal of the 5-, 3-, or 3'-oh in quercetin led to a sharp decrease in activity. thus, 3- and 5-oh as well as 3',4'-di ... | 2012 | 23067328 |
| exploiting genes and functional diversity of chlorogenic acid and luteolin biosyntheses in lonicera japonica and their substitutes. | chlorogenic acids (cgas) and luteolin are active compounds in lonicera japonica, a plant of high medicinal value in traditional chinese medicine. this study provides a comprehensive overview of gene families involved in chlorogenic acid and luteolin biosynthesis in l. japonica, as well as its substitutes lonicera hypoglauca and lonicera macranthoides. the gene sequence feature and gene expression patterns in various tissues and buds of the species were characterized. bioinformatics analysis reve ... | 2014 | 23085319 |
| wound repair and anti-inflammatory potential of lonicera japonica in excision wound-induced rats. | lonicera japonica thunb. (caprifoliaceae), a widely used traditional chinese medicinal plant, is used to treat some infectious diseases and it may have uses as a healthy food and applications in cosmetics and as an ornamental groundcover. the ethanol extract of the flowering aerial parts of l. japonica (ljee) was investigated for its healing efficiency in a rat excision wound model. | 2012 | 23173654 |
| epimedium koreanum nakai water extract exhibits antiviral activity against porcine epidermic diarrhea virus in vitro and in vivo. | porcine epidemic diarrhea virus (pedv) causes diarrhea of pigs age-independently and death of young piglets, resulting in economic loss of porcine industry. we have screened 333 natural oriental herbal medicines to search for new antiviral candidates against pedv. we found that two herbal extracts, kiom 198 and kiom 124, contain significant anti-ped viral effect. kiom 198 and kiom 124 were identified as epimedium koreanum nakai and lonicera japonica thunberg, respectively. the further plaque and ... | 2012 | 23259003 |
| screening and identification of the antibacterial bioactive compounds from lonicera japonica thunb. leaves. | our aim was to screen for antibacterial bioactive compounds from lonicera japonica leaves. staphylococcus aureus and escherichia coli were used as the indicator bacteria. bacteriostatic assay-guided extraction and stepwise partitioning of the samples yielded five compounds of interest. antimicrobial activities of the compounds were determined using a disk diffusion assay. extracts, fractions, and compounds from l. japonica leaves possessed considerable antibacterial activities against the tested ... | 2012 | 23265495 |
| [cloning and bioinformatic analysis of fatb genes in lonicera japonica thunb and its substitutes]. | a fatb unigene was obtained from the transcriptome dataset of lonicera japonica thunb. full-length fatb cdna was cloned from buds of lonicera japonica thunb., lonicera japonica thunb. var. chinensis (wats.) bak., lonicera hypoglauca miq. and lonicera dasystyla rehd. using rt-pcr technology, and named as ljfatb, lhfatb, ljcfatb and ldfatb. the results of bioinformatic analysis showed that ljfatb, ljcfatb, lhfatb and ldfatb and arabidopsis thaliana atfatb had a closely relationship. nucleotide seq ... | 2012 | 23289155 |
| adaptive divergence at the margin of an invaded range. | invasive plant species threaten biological communities globally. however, relatively little is known about how evolutionary processes vary over the course of an invasion. to evaluate the importance of historical and adaptive drivers of range expansion, we compare the performance of north american populations of invasive lonicera japonica from areas established 100-150 years ago, now the southern core of the range, to populations from the northern range margin, established within the last 65 year ... | 2012 | 23461323 |
| [regularity of changes in chlorogenic acids in lonicera japonica extracts by hplc-dad-esi-ms/ms]. | to analyze chlorogenic acids contained in lonicera japonica water extracts, and to investigate the regularity of changes in chlorogenic acids during the water extraction process. | 2012 | 23477140 |
| [authentication of lonicera japonica using bidirectional pcr amplification of specific alleles]. | to identify snp in flos lonicerae, and authenticate lonicera japonica from its adulterants and the mixture by using bidirectional pcr amplification of specific alleles (bi-pasa). | 2012 | 23627173 |
| cloning and characterization of lonicera japonica p-coumaroyl ester 3-hydroxylase which is involved in the biosynthesis of chlorogenic acid. | lonicera japonica is used in chinese medicine as a source of antioxidants, primarily flavonoids, and a phenolic acid chlorogenic acid (cga). here we report the isolation and characterization of the full-length cdna of ljc3h, a gene encoding p-coumaroyl ester 3-hydroxylase, an enzyme involved in cga synthesis. phylogenetic analysis indicated that is protein belongs to the cyp98a subfamily, and homology modeling revealed that its structure resembles that of other cytochrome p450 family proteins. s ... | 2013 | 23832359 |
| inhibition of experimental systemic inflammation (septic inflammation) and chronic bronchitis by new phytoformula bl containing broussonetia papyrifera and lonicera japonica. | broussonetia papyrifera and lonicera japonica have long been used in the treatment of inflammatory disorders in chinese medicine, especially respiratory inflammation. previously, a new phytoformula (bl) containing b. papyrifera and l. japonica was found to exert strong anti-inflammatory activity against several animal models of inflammation, especially against an animal model of acute bronchitis. in the present investigation, the effects of bl on animal models of septic inflammation and chronic ... | 2013 | 24009861 |
| effects of inhalable microparticle of flower of lonicera japonica in a mouse model of copd. | flower of lonicera japonica (flj) is a traditional herbal medicine widely used in east asia as an anti-inflammatory and anti-oxidative agent. the purpose of this study is to develop an inhalable powder formulation of flj and to evaluate its biological effects in a mouse model of chronic obstructive pulmonary disease (copd). | 2014 | 24211495 |
| homosecoiridoid alkaloids with amino acid units from the flower buds of lonicera japonica. | nine new homosecoiridoid alkaloids, named lonijaposides o-w (1-9), along with 19 known compounds, were isolated from an aqueous extract of the flower buds of lonicera japonica. their structures and absolute configurations were determined by spectroscopic data analysis and chemical methods. lonijaposides o-w have structural features that involve amino acid units sharing the n atom with a pyridinium (1-5) or nicotinic acid (6-9) moiety. the absolute configurations of the amino acid units were dete ... | 2013 | 24279769 |
| a refined-jinqi-jiangtang tablet ameliorates prediabetes by reducing insulin resistance and improving beta cell function in mice. | refined-jq (jq-r) is a mixture of refined extracts from three major herbal components of jinqi-jiangtang tablet: coptis chinensis (ranunculaceae), astragalus membranaceus (leguminosae), and lonicera japonica (caprifoliaceae). our previous studies have indicated that jq-r could decrease fasting blood glucose levels in diabetic mice and insulin resistance mice. investigating the hypoglycemic effect of jq-r on prediabetes has practical application value for preventing or delaying insulin resistance ... | 2014 | 24286962 |
| tyrosinase inhibitory effect and antioxidative activities of fermented and ethanol extracts of rhodiola rosea and lonicera japonica. | this is the first study to investigate the biological activities of fermented extracts of rhodiola rosea l. (crassulaceae) and lonicera japonica thunb. (caprifoliaceae). alcaligenes piechaudii cc-esb2 fermented and ethanol extracts of rhodiola rosea and lonicera japonica were prepared and the antioxidative activities of different concentrations of samples were evaluated using in vitro antioxidative assays. tyrosinase inhibition was determined by using the dopachrome method with l-dopa as substra ... | 2013 | 24307875 |
| [antibody preparation and enzyme linked immunosorbent assay of lonicera japonica phenylalnine ammonia lyase]. | the expression of phenylalnine ammonia lyase (ljpal1) is closely related to the content of active compounds in lonicera japonica. in this paper, a prokaryotic expression vector is constructed and ljpal1 protein is expressed in e. coli. three antigen sites were synthesized to peptide antigen and prepared polyclonal antibody of anti-ljt-1, anti-ljt-2 and anti-ljt-3, separately. antibody anti-ljt-2 was screened using western blotting. and indirect elisa was built using anti-ljt-2. the results of th ... | 2013 | 24358787 |
| therapeutic effect of broussonetia papyrifera and lonicera japonica in ovalbumin-induced murine asthma model. | broussonetia papyrifera (l.) vent. and lonicera japonica thunb. have been used in recent medicinal research for their antioxidative and anti-inflammatory properties. the present study investigated the therapeutic efficacy of b. papyrifera and l. japonica ethanolic extracts in a murine model of ovalbumin-induced asthma, in which intra-peritoneal (ip) injections and aerosol ovalbumin delivery were used to induce allergic asthma. bronchioalveolar lavage fluid (balf), serum samples, lungs and livers ... | 2013 | 24427953 |
| predicting the function of 4-coumarate:coa ligase (lj4cl1) in lonicera japonica. | 4-coumarate:coa ligases (4cls) are a group of essential enzymes involved in the pathway of phenylpropanoid-derived compound metabolisms; however it is still difficult to identify orthologs and paralogs of these important enzymes just based on sequence similarity of the conserved domains. using sequence data of 20 plant species from the public databases and sequences from lonicera japonica, we define 1252 adenosine monophosphate (amp)-dependent synthetase/ligase sequences and classify them into t ... | 2014 | 24518682 |
| comparison of anti-bacterial activity of three types of di-o-caffeoylquinic acids in lonicera japonica flowers based on microcalorimetry. | the anti-bacterial activities of three types of di-o-caffeoylquinic acids (dicqas) in lonicera japonica flowers, a traditional chinese medicine (tcm), on bacillus shigae growth were investigated and compared by microcalorimetry. the three types of dicqas were 3, 4-di-o-caffeoylquinic acid (3, 4-dicqa), 3, 5-di-o-caffeoylquinic acid (3, 5-dicqa), and 4, 5-di-o-caffeoylquinic acid (4, 5-dicqa). some qualitative and quantitative information of the effects of the three dicqas on metabolic power-time ... | 2014 | 24636060 |
| cloning and expression analysis of the lonicera japonica thunb. chlorogenic acid synthetase gene (ljccoaomt1) in rice. | complete coding dna sequences of a closely related chlorogenic acid synthetase gene (ljccoaomt1) were isolated from lonicera japonica thunb. by reverse transcription polymerase chain reaction (rt-pcr) and rapid amplification of cdna ends (race). ljccoaomt1 was subsequently overexpressed in escherichia coli and a 25-kd protein was detected by electrophoresis and western blot analysis. high-performance liquid chromatography (hplc) analysis showed that recombinant ljccoaomt1 methylates the caffeic ... | 2014 | 24737465 |
| [restriction endonuclease digest - melting curve analysis: a new snp genotyping and its application in traditional chinese medicine authentication]. | single nucleotide polymorphisms (snp) is an important molecular marker in traditional chinese medicine research, and it is widely used in tcm authentication. the present study created a new genotyping method by combining restriction endonuclease digesting with melting curve analysis, which is a stable, rapid and easy doing snp genotyping method. the new method analyzed snp genotyping of two chloroplast snp which was located in or out of the endonuclease recognition site, the results showed that ... | 2014 | 24974477 |
| effects of plant extracts on microbial population, methane emission and ruminal fermentation characteristics in in vitro. | this study was conducted to evaluate effects of plant extracts on methanogenesis and rumen microbial diversity in in vitro. plant extracts (artemisia princeps var. orientalis; wormwood, allium sativum for. pekinense; garlic, allium cepa; onion, zingiber officinale; ginger, citrus unshiu; mandarin orange, lonicera japonica; honeysuckle) were obtained from the plant extract bank at korea research institute of bioscience and biotechnology. the rumen fluid was collected before morning feeding from a ... | 2012 | 25049630 |
| screening and identification of multi-components in re du ning injections using lc/tof-ms coupled with uv-irradiation. | a high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry-uv-irradiation (hplc-qtof-ms-uv) method was established for rapid separation and structural identification of the constituents in re du ning injections (rdni). a total of 20 potentially bioactive compounds including 10 caffeoylquinic acids and 10 iridoid glycosides were identified or tentatively characterized in rdni by comparing their retention times and ms spectra with those of authentic standards or literatur ... | 2015 | 25265866 |
| luteolin inhibited the gene expression, production and secretion of muc5ac mucin via regulation of nuclear factor kappa b signaling pathway in human airway epithelial cells. | luteolin, a flavonoidal compound derived from lonicera japonica thunb. and chrysanthemum indicum l., has been reported to show anti-inflammatory, anti-oxidative and anti-carcinogenic effects. in this study, we investigated whether luteolin significantly affects the secretion, production and gene expression of airway mucin. confluent nci-h292 cells were pretreated with luteolin for 30 min and then stimulated with egf (epidermal growth factor) or pma (phorbol 12-myristate 13-acetate) for 24 h or t ... | 2015 | 25285988 |
| a dna barcoding approach to characterize pollen collected by honeybees. | in the present study, we investigated dna barcoding effectiveness to characterize honeybee pollen pellets, a food supplement largely used for human nutrition due to its therapeutic properties. we collected pollen pellets using modified beehives placed in three zones within an alpine protected area (grigna settentrionale regional park, italy). a dna barcoding reference database, including rbcl and trnh-psba sequences from 693 plant species (104 sequenced in this study) was assembled. the database ... | 2014 | 25296114 |
| transcriptome-wide analysis of same superfamily to novelty phosphoethanolamine n-methyltransferase copy in lonicera japonica. | the s-adenosyl-l-methionine-dependent methyltransferase superfamily plays important roles in plant development. the buds of lonicera japonica are used as chinese medical material and foods; chinese people began domesticating l. japonica thousands of years ago. compared to the wild species, l. japonica var. chinensis, l. japonica gives a higher yield of buds, a fact closely related to positive selection over the long cultivation period of the species. genome duplications, which are always detecte ... | 2014 | 25551601 |
| the multi-targets integrated fingerprinting for screening anti-diabetic compounds from a chinese medicine jinqi jiangtang tablet. | jinqi jiangtang tablet is a traditional chinese anti-diabetic formula containing three ingredients: coptis chinensis franch. (dried rhizome of c. chinensis franch., coptis deltoidea c. y. cheng et hsiao and coptis teeta wall.), astragalus membranaceus (fisch.) bunge. (dried root of a. membranaceus (fisch.) bge. var. mongholicus (bge. ) hsiao and a. membranaceus (fisch.) bge. ) and lonicera japonica thunb. (dried alabastrum or with nascent flowers of l. japonica thunb. ). free radicals, α-glucosi ... | 2015 | 25698248 |
| effect of lonicera japonica extract on mycoplasma gallisepticum in naturally infected broiler flocks. | 1. in this study, the effect of chlorogenic acid extract from lonicera japonica thunb. on mycoplasma gallisepticum infections and the performance of broiler flocks was investigated. 2. a total of 360 ross-308 broiler chicks taken from m. gallisepticum seropositive flocks were divided equally into three groups designated as control (nothing administered), antibiotic (tylosin tartrate given for the first 3 d and d 20-22) and test group (chlorogenic acid extract given twice a day on d 16 and 22). 3 ... | 2015 | 25731588 |
| [near infrared spectroscopy on-line and real-time monitoring of alcohol precipitation process of reduning injection]. | near infrared (nir) spectroscopy as a kind of rapid process analysis technology has been successfully applied in chinese medicine pharmaceutical process. in this research, the technology was adopted to establish the rapid quantitative analysis models of main indicators from the lonicera japonica and artemisia annua alcohol precipitation process of reduning injection. on-line nir spectra of 142 samples from alcohol precipitation process were collected and the content of main indicators for each s ... | 2014 | 25911810 |
| research on the change of chemical composition in productive process of re du ning injection by hplc/q-tof ms. | a high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (hplc/q-tof ms) was developed for the analysis of chemical composition change in the production process of re du ning injection, a chinese medicine preparation with a combination of lonicera japonica thunb., gardenia jasminoides ellis and artemisia annua l. a total of 90 compounds from raw materials-intermediates-re du ning injection were detected; among them, 55 compounds were identified or tentati ... | 2016 | 26058547 |
| [bioinformatics analysis of dna demethylase genes in lonicera japonica thunb]. | the dna demethylase genes are widespread in plants. four dna demethylase genes (ljdme1, ljdme2, ljdme3 and ljdme4) were obtained from transcriptome dataset of lonicera japonica thunb by using bioinformatics methods and the proteins' physicochemical properties they encoded were predicted. the phylogenetic tree showed that the four dna demethylase genes and arabidopsis thaliana dme had a close relationship. the result of gene expression model showed that four dna demethylase genes were different b ... | 2015 | 26118119 |
| on-line quantitative monitoring of liquid-liquid extraction of lonicera japonica and artemisia annua using near-infrared spectroscopy and chemometrics. | liquid-liquid extraction of lonicera japonica and artemisia annua (jq) plays a significant role in manufacturing reduning injection. many process parameters may influence liquid-liquid extraction and cause fluctuations in product quality. | 2017 | 26246744 |
| antifungal potential of essential oil and ethanol extracts of lonicera japonica thunb. against dermatophytes. | the antifungal potential of essential oil and ethanolic leaf extracts of lonicera japonica thunb. was evaluated for controlling the growth of dermatophytes. the oil (1,000 ppm) and extracts (1,500 ppm) of l. japonica revealed 55.1-70.3 % and 40.1-65.5 % antidermatophytic effect against microsporum canis kctc 6348, 6349, 6591, trichophyton rubrum kctc 6345, 6352, 6375, trichophyton mentagrophytes kctc 6077 and 6085, respectively, along with their respective minimum inhibitory concentrations rangi ... | 2014 | 26417269 |
| an improved method for thin layer chromatographic analysis of saponins. | analysis of saponins by thin layer chromatography (tlc) is reported. the solvent system was n-butanol:water:acetic acid (84:14:7). detection of saponins on the tlc plates after development and air-drying was done by immersion in a suspension of sheep erythrocytes, followed by washing off the excess blood on the plate surface. saponins appeared as white spots against a pink background. the protocol provided specific detection of saponins in the saponins enriched extracts from aesculusindica (wall ... | 2012 | 26434348 |
| [study of screening pseudoallergenic substances of shuanghuanglian injection]. | in this study, chemistry, biology and pharmacology were combinated to screen pseudoallergenic substances of shuang-huanglian injection (shli) so that to establish a scientific and systematic approach to screen pseudoallergenic substances of traditional chinese medicine injections. the mouse pseudoallergic reaction models were used to screen the pseudoallergic reaction of shli's intermediate extract and the intermediate extract's component or ingredient. among the three intermediates of shuanghua ... | 2015 | 26666017 |