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artificial infection of the bed bug with rickettsia parkeri.although a variety of disease agents have been reported from bed bugs, the mechanical and biological disease transmission potential of bed bugs remains unelucidated. in this study we assayed survivability of the mildly pathogenic spotted fever group rickettsia, rickettsia parkeri, in bed bugs after feeding on r. parkeri-infected chicken blood. two groups of 15 adult bed bugs each were fed on infected or noninfected blood, and two groups of fourth-instar bed bugs also were fed on either infected ...201222897053
can travellers avoid bed bug bites? 201222926286
tracking bed bugs (cimex lectularius): a study of the effect of physiological and extrinsic factors on the response to bed bug-derived volatiles.the common bed bug, cimex lectularius, feeds on the blood of mammal and bird hosts, and is a pest of global importance. semiochemicals are chemicals involved in animal communication that may affect behaviour and/or physiology. attractive semiochemicals that play a role in mediating bed bug behaviour could be exploited for the development of a highly effective novel monitoring device. tracking software was used to record the response of bed bugs to volatiles from paper previously exposed to consp ...201322996447
bed bugs: they are back! the role of the school nurse in bed bug management.recently there has been a resurgence of bed bugs in all facets of our society. bed bugs have even been found in schools, causing unnecessary exclusion of students and unfounded hysteria. school nurses are again called upon to be front-line sources of information to quell the hysteria and confusion related to this unsavory condition. by arming themselves with the best evidence regarding proper identification of bed bugs and their bites and information about integrated prevention measures to contr ...201223008871
mental health effects from urban bed bug infestation (cimex lectularius l.): a cross-sectional study.to assess whether bed bug infestation was linked to sleep disturbances and symptoms of anxiety and depression.201223015597
carbon dioxide fumigation for controlling bed bugs.we investigated the potential of carbon dioxide (co2) fumigation as a method for controlling bed bugs, cimex lectularius l. the effect of bed bug developmental stage, temperature, and co2 concentration on the minimum time to kill 100% of bed bugs was determined. the minimum co2 concentration lethal to all bed bug stages was approximately 30% with 24 h exposure time at 25 degrees c. the minimum fumigation time required to kill 100% of eggs using 100% co2 at 20, 25, and 30 degrees c were 3, 7, and ...201223025189
bed bugs in healthcare settings.infestations caused by bed bugs have resurfaced during the past decade across all continents. even though bed bugs primarily cause skin manifestations in humans, a major stigma is placed upon people or institutions found to carry them. it is important for healthcare facilities to be prepared for this pest by implementing policies, carefully selecting materials used for hospital furniture, and educating providers on early identification and control.201223041813
potential population growth and harmful effects on humans from bed bug populations exposed to different feeding regimes.effects of host availability and feeding period on bed bugs, cimex lectularius (l.) (hemiptera: cimicidae), were measured. population growth and the potential harmful effect of bed bug populations on human hosts were modelled. bloodmeal sizes were affected by both feeding length and frequency, with >2-fold difference between insects fed daily or weekly. blood consumption increased >2-fold between bed bugs fed occasionally and often, and 1.5-fold between occasional and daily feeding. bed bugs fed ...201323046478
bed bug basics. 201223072210
susceptibility of cimex lectularius (hemiptera: cimicidae) to pyrethroid insecticides and to insecticidal dusts with or without pyrethroid insecticides.relative increases of bed bug, cimex lectularius l., populations are probably due in large measure to their resistance to pyrethroids, which have been used extensively against urban pests. a connecticut population of bed bugs was assessed for sensitivity to pyrethroids and exposed to commonly-used commercial insecticides applied to various substrates on which the residues were allowed to age for 0-24 wk. type i and type ii pyrethroids differed in toxicity when applied at a high dosage (1 microg) ...201223156178
infestation by pyrethroids resistant bed bugs in the suburb of paris, france.bed bugs are hematophagous insects responsible for a re-emerging and challenging indoor pest in many countries. bed bugs infestations may have health consequences including nuisance biting, cutaneous and systemic reactions. this resurgence can probably be attributed to factors such as increased international travel and development of resistance against insecticides. resistance against pyrethroids has been reported several times from the usa and rarely in europe. in france, very few data on bed b ...201223193523
[unclear pruritic and urticarial skin inflammation. bed bug attack].a 27-year-old woman presented with severe pruritus for a few weeks and diffuse urticarial erythema with pinhead-sized papules over the entire body. the skin lesions occurred directly after a stay in her secondary residence in london. the medical history, clinical picture and histological feature of an arthropod reaction in the skin biopsy, coupled with patient offering a bed bug specimen as evidence, secured the diagnosis of a cimicosis.201323223900
real-time measurement of volatile chemicals released by bed bugs during mating activities.in recent years, bed bug (hemiptera: cimicidae) problems have increased dramatically in many parts of the world, leading to a renewed interest in their chemical ecology. most studies of bed bug semiochemicals have been based on the collection of volatiles over a period of time followed by chemical analysis. here we present for the first time, a combination of proton transfer reaction mass spectrometry and video analysis for real-time measurement of semiochemicals emitted by isolated groups of be ...201223227225
what's eating you? bedbugs revisited (cimex lectularius). 201223259201
otitis from the common bedbug.there is a resurgence of interest in the biology and clinical disease associated with cimex lectularius, as the common bed bug is becoming more prevalent in well-developed countries. a patient presented with complaints of right ear irritation for several days' duration. a foreign body was lavaged from the ear canal, which proved to be an engorged nymphal form of cimex lectularius. the parasite had apparently obtained a blood feed from the tympanic membrane. the resolution of the illness was unre ...201223277805
bedbugs: a primer for the health-system pharmacist.the history and life cycle of bedbugs, the identification and supportive treatment of bedbug bites, and the eradication and prevention of bedbug infestations are reviewed.201323292265
bugging forecast: unknown, disliked, occasionally intimate. bed bugs in germany meet unprepared people.bed bugs appear to be feared more than vector insects and other household pests. the reasons for this exaggerated fear are not fully understood. one hypothesis is that the folk knowledge on recognising and controlling bed bugs decreased as bed bugs became rarer in the 1960s and led to irrational perceptions. here, we examine people's ability to recognise a bed bug and their response what to do in case of an infestation. we found that 13% of a sample of 391 people in four large german cities reco ...201323300947
threat and efficacy uncertainty in news coverage about bed bugs as unique predictors of information seeking and avoidance: an extension of the eppm.an experiment was conducted from the perspective of the extended parallel process model (eppm) investigating readers' responses to print news stories about the issue of bed bugs. stories containing reference to (a) the threat of bed bugs and (b) efficacy of the solution were manipulated to vary the level of certainty with which the variables were discussed. results suggest that stories referencing uncertainty regarding presence of the bed-bug threat may be more likely to motivate intention to se ...201323330859
bed bug infestation. 201323341545
bed bug saliva causes release of monocytic inflammatory mediators: plausible cause of cutaneous bite reactions.bed bugs may cause mild to severe cutaneous reactions. we studied the ability of bed bug salivary extract (sge) to induce inflammatory reactions responsible for cutaneous manifestations and found that sge stimulated the production of several potent chemokines and cytokines from macrophages. chemokines induced by sge included those known to recruit eosinophils (eotaxin), attract neutrophils [interleukin (il)-8] or induce their survival and proliferation (granulocyte colony-stimulating factor). cy ...201323343710
efficacy of commercially available ultrasonic pest repellent devices to affect behavior of bed bugs (hemiptera: cimicidae).little is known about the potential for acoustic communication in bed bugs, cimex lectularius l. (hemiptera: cimicidae), or the use of sound as cues in host location, although many hemipterans are known to communicate with sound. most behavioral research has focused on bed bug pheromones that are used in aggregation and as alarm signals. we investigated the influence of sound as a deterrent and as an attractant, either of which could ultimately be used to monitor and control bed bugs. female bed ...201223356076
comparison of multiple steam treatment durations for control of bed bugs (cimex lectularius l.).the factors contributing to the current resurgence of bed bug cimex lectularius l. populations across the united states and elsewhere include, among others, the development of resistance to chemical insecticides and population management practices. this has led to the development and attempted refinement of many non-chemical control methods that contribute to an ipm approach to solving the current bed bug population density increase in urban dwellings. one such approach is the use of heat in the ...201323371878
human travel and traveling bedbugs.a dramatic increase of reported bedbug (cimex lectularius and cimex hemipterus) infestations has been observed worldwide over the past decade. bedbug infestations have also been detected across a wide range of travel accommodations, regardless of their comfort and hygiene levels. travelers are increasingly exposed to the risks of bedbug bites, infestation of personal belongings, and subsequent contamination of newly visited accommodations and their homes.201223379708
molecular characterization of genes encoding inward rectifier potassium (kir) channels in the bed bug (cimex lectularius).the molecular genetics of inward-rectifier potassium (kir) channels in insects is poorly understood. to date, kir channel genes have been characterized only from a few representative dipterans (i.e., fruit flies and mosquitoes). the goal of the present study was to characterize kir channel cdnas in a hemipteran, the bed bug (cimex lectularius). using our previously reported bed bug transcriptome (rna-seq), we identified two cdnas that encode putative kir channels. one was a full-length cdna that ...201323416179
insect bite reactions.insects are a class of living creatures within the arthropods. insect bite reactions are commonly seen in clinical practice. the present review touches upon the medically important insects and their places in the classification, the sparse literature on the epidemiology of insect bites in india, and different variables influencing the susceptibility of an individual to insect bites. clinical features of mosquito bites, hypersensitivity to mosquito bites epstein-barr virus nk (hmb-ebv-nk) disease ...201323442453
evaluation of an insecticide dust band treatment method for controlling bed bugs.current bed bug, cimex lectularius l., control usually involves insecticide applications that pose a high risk of insecticide exposure to residents and applicators. to minimize these risks and the amount of insecticides used, we designed and evaluated a dust band treatment technique. the laboratory assay showed that 1% cyfluthrin dust treated bands are highly effective in killing bed bugs. we further evaluated this technique in bed bug infested apartments. the "dust band" treatment consisted of ...201323448050
photoacoustically-guided photothermal killing of mosquitoes targeted by nanoparticles.in biomedical applications, nanoparticles have demonstrated the potential to eradicate abnormal cells in small localized pathological zones associated with cancer or infections. here, we introduce a method for nanotechnology-based photothermal (pt) killing of whole organisms considered harmful to humans or the environment. we demonstrate that laser-induced thermal, and accompanying nano- and microbubble phenomena, can injure or kill c. elegans and mosquitoes fed carbon nanotubes, gold nanosphere ...201423450780
[bed bugs]. 201223451421
bed bugs evolved unique adaptive strategy to resist pyrethroid insecticides.recent advances in genomic and post-genomic technologies have facilitated a genome-wide analysis of the insecticide resistance-associated genes in insects. through bed bug, cimex lectularius transcriptome analysis, we identified 14 molecular markers associated with pyrethroid resistance. our studies revealed that most of the resistance-associated genes functioning in diverse mechanisms are expressed in the epidermal layer of the integument, which could prevent or slow down the toxin from reachin ...023492626
a quantitative analysis of a modified feeding method for rearing cimex lectularius (hemiptera: cimicidae) in the laboratory.a modified artificial feeding system was developed for rearing cimex lectularius and compared with the most widely used artificial feeding method which requires custom-made glassware and a circulating water bath to warm the blood. the petri dish method reduces some of the drawbacks from the current water bath method, such as the possibility of flooding bed bug rearing jars with water or blood and the need for expensive custom-made glassware.201323509084
effects of bed bug saliva on human skin. 201323552994
bed bug detection: current technologies and future directions.technologies to detect bed bugs have not kept pace with their global resurgence. early detection is critical to prevent infestations from spreading. detection based exclusively on bites is inadequate, because reactions to insect bites are non-specific and often misdiagnosed. visual inspections are commonly used and depend on identifying live bugs, exuviae, or fecal droplets. visual inspections are inexpensive, but they are time-consuming and unreliable when only a few bugs are present. use of a ...201323553226
targetoid lesions in the emergency department. bed bug bites (cimex lectularius) with targetoid lesions on initial presentation. 201323553426
entrapment of bed bugs by leaf trichomes inspires microfabrication of biomimetic surfaces.resurgence in bed bug infestations and widespread pesticide resistance have greatly renewed interest in the development of more sustainable, environmentally friendly methods to manage bed bugs. historically, in eastern europe, bed bugs were entrapped by leaves from bean plants, which were then destroyed; this purely physical entrapment was related to microscopic hooked hairs (trichomes) on the leaf surfaces. using scanning electron microscopy and videography, we documented the capture mechanism: ...201323576783
a 454 survey reveals the community composition and core microbiome of the common bed bug (cimex lectularius) across an urban landscape.elucidating the spatial dynamic and core constituents of the microbial communities found in association with arthropod hosts is of crucial importance for insects that may vector human or agricultural pathogens. the hematophagous cimex lectularius (hemiptera: cimicidae), known as the human bed bug, has made a recent resurgence in north america, as well as worldwide, potentially owing to increased travel, climate change and resistance to insecticides. a comprehensive survey of the bed bug microbio ...201323585900
[dermatitis and arthropods (anobium punctatum and cimex lectularius) in summer: three case reports].we report three cases of pruritic dermatitis with erythematous maculopapules, having a similar clinical presentation, in summer, and caused by two different arthropods. in wandering diagnosis since sometimes several months, patients have made entomologic investigations in their home. two of three samples, have shown an infestation by anobium punctatum, the common furniture beetle, a xylophagous beetle (usually harmless for human). it may be parasited by pyemotes ventricosus, a mite known since t ...201323587582
bed bugs and public health: new approaches for an old scourge.to share four canadian cities' experiences with bed bug infestations and to explore public health roles in managing them.201223618015
increasing use of pyrethroids in canadian households: should we be concerned?pyrethroids are a class of plant-derived insecticides and their man-made analogues that are increasingly applied in canada as first choice for pest control in many agricultural and residential settings. their popularity is partly due to their alleged safety compared to the older organochlorine and organophosphate insecticides. application of pyrethroids is expanding because of recent increases in the level of pest infestations--such as bed bugs--and the decreased susceptibility of target species ...201223618016
bed bugs reproductive life cycle in the clothes of a patient suffering from alzheimer's disease results in iron deficiency anemia.we report the case of an 82-year-old patient, hospitalized for malaise. her clothes were infested by numerous insects and the entomological analysis identified them as being cimex lectularius (bed bugs). the history of the patient highlighted severe cognitive impairment. the biological assessment initially showed a profound microcytic, aregenerative, iron deficiency anemia. a vitamin b12 deficiency due to pernicious anemia (positive intrinsic factor antibodies) was also highlighted, but this was ...201323673315
bed bugs, their blood sources and life history parameters: a comparison of artificial and natural feeding.a blood-feeding system that utilizes a small amount of whole heparinized human blood in parafilm bags is described in detail, and similarities and differences between artificially fed and naturally rodent-fed bed bugs (hemiptera: cimicidae) are discussed. blood with high levels of heparin (10%) was unsuitable for artificial colony rearing, whereas bed bugs fed on 1% heparinized blood and those that naturally ingested rat blood completed their lifecycle with similar stage structures over time, wi ...201423692154
bed bugs in hospitals: more than just a nuisance. 201323775615
no sex-related differences in mortality in bed bugs (hemiptera: cimicidae) exposed to deltamethrin, and surviving bed bugs can recover.exposure of a pyrethroid-susceptible strain of bed bugs, cimex lectularius l. (hemiptera: cimicidae) to varying concentrations of deltamethrin for 24 h indicated no significant difference in mortality between males, females, and nymphs at 24 nor at 168 h postexposure when bed bugs were removed to untreated surfaces at 24 h. in addition, many bed bugs classified as morbid or moribund at 24 h and removed to untreated surfaces at this time, recovered by 336 h (2 wk) and were capable of feeding when ...201323786091
suicide following an infestation of bed bugs.male, 62.201323826461
ivermectin causes cimex lectularius (bedbug) morbidity and mortality.bedbug infestations are increasing across north america and europe, with more people presenting to emergency departments for treatment. physicians cannot provide substantive treatment for people affected by bedbugs.201323871326
self-reported bed bug infestation among new york city residents: prevalence and risk factors.bed bug infestations have risen precipitously in urban areas. little is known about risk factors for infestations or health outcomes resulting from these infestations. in the 2009 community health survey, which is a representative population-based survey, 9,934 noninstitutionalized adults in new york city reported on bed bug infestations requiring an exterminator in the past year. the authors estimated infestation prevalence and explored predictors of infestation and associations between infesta ...201323947287
bed bugs and infectious disease: a case for the arboviruses. 201323966852
two different lineages of bedbug (cimex lectularius) reflected in host specificity.co-speciation between host-parasite species is generally thought to result in mirror-image congruent phylogenies. for the last several centuries, many bat species have been turning synanthropic, especially those that are hosted by bedbugs in europe. there is evidence of only limited gene flow from the population of people to the population of bats. this study was focused on comparison of survival, development, and the reproduction rate based on cross-feeding experiments. in our research, we used ...201323982311
standard metabolic rate of the bed bug, cimex lectularius: effects of temperature, mass, and life stage.metabolic rates provide important information about the biology of organisms. for ectothermic species such as insects, factors such as temperature and mass heavily influence metabolism, but these effects differ considerably between species. in this study we examined the standard metabolic rate of the bed bug, cimex lectularius l. we used closed system respirometry and measured both o2 consumption and co2 production across a range of temperatures (10, 20, 25, 30, 35°c) and life stages, while also ...201324013075
effect of trap design, chemical lure, carbon dioxide release rate, and source of carbon dioxide on efficacy of bed bug monitors.bed bugs, (cimex lectularius l.), are difficult to find because of their nocturnal and secretive behavior. in recent years, a number of monitors containing carbon dioxide (co2), chemical lures, heat, or both, to attract bed bugs have been developed for detecting bed bugs. ineffective trap design, lack of attraction of chemical lures, high cost of the co2 delivery system, or insufficient co release rates are some factors that limited the wide adoption of these monitors. to develop an affordable a ...201324020296
survey of bartonella spp. in u.s. bed bugs detects burkholderia multivorans but not bartonella.bed bugs (cimex lectularius l.) have resurged in the united states and globally. bed bugs are hematophagous ectoparasites of humans and other animals, including domestic pets, chickens, and bats, and their blood feeding habits contribute to their potential as disease vectors. several species of bartonella are re-emergent bacterial pathogens that also affect humans, domestic pets, bats and a number of other wildlife species. because reports of both bed bugs and bartonella have been increasing in ...201324040015
horizontal transfer of diatomaceous earth and botanical insecticides in the common bed bug, cimex lectularius l.; hemiptera: cimicidae.horizontal transfer of insecticide occurs when insects contact or ingest an insecticide, return to an aggregation or a nest, and transfer the insecticide to other conspecific insects through contact. this phenomenon has been reported in a number of insects including social insects, however it has not been reported in bed bugs. since horizontal transfer can facilitate the spread of insecticide into hard to reach spaces, it could contribute greatly to the management of these public health pests.201324086593
blood constituents as phagostimulants for the bed bug cimex lectularius l.many hematophagous arthropods are stimulated by blood constituents to initiate feeding. we used a membrane-based feeding system to identify chemicals that stimulate acceptance and engorgement responses in various life stages of bed bugs. water was fortified with a variety of compounds (e.g. salts, amino acids, vitamins, nucleotides, cholesterol and fatty acids) in these bioassays. atp was the most effective phagostimulant in adults and nymphs, resulting in >70% of bed bugs fully engorging. addit ...201424198260
out for blood: growing numbers of bed bugs, mosquitoes, and ticks are spreading misery and frustrating lawmakers. 201324199291
identification and management of bed bug infestations in austere environments.military forces have missions that send them all over the globe. with the reemergence of bed bugs worldwide, the possibility of servicemembers encountering them has increased. special operations forces are often sent to locations that may not have integrated pest management support. knowing how to identify and manage a bed bug infestation, with and without proper equipment and supplies, may become necessary in the very near future. it is also important that servicemembers are aware of how bed bu ...201324227555
karyotypes, male meiosis and comparative fish mapping of 18s ribosomal dna and telomeric (ttagg) n repeat in eight species of true bugs (hemiptera, heteroptera).eight species belonging to five true bug families were analyzed using dapi/cma3-staining and fluorescence in situ hybridization (fish) with telomeric (ttagg)n and 18s rdna probes. standard chromosomal complements are reported for the first time for deraeocoris rutilus (herrich-schäffer, 1838) (2n=30+2m+xy) and deraeocoris ruber(linnaeus, 1758) (2n=30+2m+xy) from the family miridae. using fish, the location of a 18s rdna cluster was detected in these species and in five more species: megaloceroea ...201124260641
increasing bedbug, cimex lectularius, infestations in kuwait.bedbug, cimex lectularius, human infestations were reported in the state of kuwait in the last 2 years. eleven separate infestations from different localities were received at the veterinary laboratories indicating that bedbug is widespread in the state of kuwait. there was circumstantial evidence to suggest the transfer of bugs with recent immigrants or used furniture. the spread of infestation can be attributed to the increase in migrant labor and their mobility inside the country. the increas ...201324260819
application of native prick test in diagnosis of bed bug allergy.the aim of the study was case report of the patient with systemic reaction after a bed bug (cimex lectularius) bite. a 23-year-old female, previously healthy, reports systemic reaction, including rash on her corpus and limbs, itching, nausea, conciseness disorder, forcing her to call the ambulance. the interview revealed that the bed bug occurs in the patient's apartment. a prick-by-prick test with bed bug excretion was made. the skin test with native allergen was strongly positive (histamine 5 ...201324278049
cases of bed bug (cimex lectularius) infestations in northwest italy.cbed bugs (cimex lectularius) have been a common problem for humans for at least 3,500 years and in europe their presence was endemic until the end of world war ii, when infestations began to decrease. however, since the beginning of the 21st century new cases of infestations have been reported in developed countries. many theories have been put forward to explain this change of direction, but none has been scientifically proven. the aim of this study is to provide some reports of bed bug infest ...201724362773
laboratory identification of arthropod ectoparasites.the collection, handling, identification, and reporting of ectoparasitic arthropods in clinical and reference diagnostic laboratories are discussed in this review. included are data on ticks, mites, lice, fleas, myiasis-causing flies, and bed bugs. the public health importance of these organisms is briefly discussed. the focus is on the morphological identification and proper handling and reporting of cases involving arthropod ectoparasites, particularly those encountered in the united states. o ...201424396136
morphology, ultrastructure and functional role of antennal sensilla in off-host aggregation by the bed bug, cimex lectularius.after blood feeding on a host, bed bugs, cimex lectularius, assemble in aggregation sites away from the host. off-host aggregation is mediated by a combination of mechanical and chemical stimuli associated with bug feces. partial antennectomies indicated removal of flagellomeres did not affect aggregation, but removal of the whole pedicel or its distal half significantly reduced (p < 0.01) aggregation, suggesting that sensilla related to off-host aggregation occur on the distal half of the pedic ...201424412653
human-facilitated metapopulation dynamics in an emerging pest species, cimex lectularius.the number and demographic history of colonists can have dramatic consequences for the way in which genetic diversity is distributed and maintained in a metapopulation. the bed bug (cimex lectularius) is a re-emerging pest species whose close association with humans has led to frequent local extinction and colonization, that is, to metapopulation dynamics. pest control limits the lifespan of subpopulations, causing frequent local extinctions, and human-facilitated dispersal allows the colonizati ...201424446663
population variation in and selection for resistance to pyrethroid-neonicotinoid insecticides in the bed bug.pyrethroid resistance in bed bugs, cimex lectularius, has prompted a change to combination products that include a pyrethroid and a neonicotinoid. ten populations of bed bugs were challenged with two combination products (temprid sc and transport ghp). susceptibility of these populations varied, with the correlated response of the two products indicating cross resistance. we imposed selection on three populations using label rate temprid, and then reared progeny from unselected and selected stra ...201424452337
extensive fragmentation of the x chromosome in the bed bug cimex lectularius linnaeus, 1758 (heteroptera, cimicidae): a survey across europe.variation in the number of chromosomes was revealed in 61 samples of cimex lectularius linnaeus, 1758 from the czech republic and other european countries, hosted on myotis kaup, 1829 (4) and homo sapiens linnaeus, 1758 (57). the karyotype of all the specimens of cimex lectularius analysed contained 26 autosomes and a varying number of the sex chromosomes. the number of sex chromosomes showed extensive variation, and up to 20 fragments were recorded. altogether, 12 distinct karyotypes were disti ...201324455100
genomic analyses of sodium channel α-subunit genes from strains of melon thrips, thrips palmi, with different sensitivities to cypermethrin.we examined the genomic organization of the sodium channel α-subunit gene in two strains of melon thrips, thrips palmi, having differing sensitivity to cypermethrin. the nucleotide sequences of the strains included 18 or 16 putative exons which covered the entire coding region of the gene producing 2039 amino acid residues. deduced amino acid sequences of both strains showed 80% homology with those of periplaneta americana and cimex lectularius. comparison of deduced amino acid sequences of both ...201424485319
cold tolerance of bed bugs and practical recommendations for control.bed bugs were exposed to freezing temperatures for various exposure times to determine cold tolerance and mortality estimates for multiple life stages. the mean supercooling point for all bed bug life stages ranged from -21.3 degrees c to -30.3 degrees c, with the egg stage reporting the lowest value. a probit analysis provided a lower lethal temperature (llt99) of -31.2 degrees c when estimates from all life stages were combined, demonstrating that all stages of bed bugs are not capable of surv ...201324498745
repellency of selected chemicals against the bed bug (hemiptera: cimicidae).in recent years, the common bed bug, cimex lectularius l. (hemiptera: cimicidae), became a major public health concern in urban communities. bed bugs are notoriously difficult to control, and their bites are not tolerated by most people. the public has an urgent need for materials and methods to reduce bed bug introduction and bites during work, travel, or sleep. a repellent product will help achieve these goals by discouraging and preventing bed bugs from moving to a protected area. we evaluate ...201324498754
rna interference of nadph-cytochrome p450 reductase of the rice brown planthopper, nilaparvata lugens, increases susceptibility to insecticides.nadph-cytochrome p450 reductase (cpr) is essential for numerous biological reactions catalysed by microsomal cytochrome p450 monooxygenases (p450s). knockdown of cpr in several insects leads to developmental defects and increased susceptibility to insecticides. however, information about the role of cpr in the brown planthopper, nilaparvata lugens, is still unavailable.201524515640
duplicated female receptacle organs for traumatic insemination in the tropical bed bug cimex hemipterus: adaptive variation or malformation?during mating, male bed bugs (cimicidae) pierce the female abdomen to inject sperm using their needle-like genitalia. females evolved specialized paragenital organs (the spermalege and associated structures) to receive traumatically injected ejaculates. in leptocimex duplicatus, the spermalege is duplicated, but the evolutionary significance of this is unclear. in cimex hemipterus and c. lectularius, in which females normally develop a single spermalege on the right side of the abdomen, similar ...201424586643
colonization of cimex lectularius with methicillin-resistant staphylococcus aureus.a recent paper published by lowe and romney in emerging infectious diseases titled, bed bugs as vectors for drug-resistant bacteria has sparked a renewed interest in bed bug vector potential. we followed a pyrethroid resistant strain of the human bed bug (cimex lectularius, l.) fed either human blood or human blood with added methicillin resistant staphylococcus aureus (mrsa) for 9 days post-feeding. results indicated that while the bed bug midgut is a hospitable environment for mrsa, the bacter ...201424589308
spatial and temporal patterns in cimex lectularius (hemiptera: cimicidae) reporting in philadelphia, pa.we analyzed a comprehensive telephone log of pest infestation reports to assess the spatial and temporal trends in cimex lectularius l. (bed bug) reporting throughout philadelphia, pa. citywide spatial analyses of reports from september 2011 to june 2012 revealed several statistically significant bed bug hotspots. however, these were small and diffuse. temporal analyses of reports from december 2008 to may 2011 detected prominent seasonality in bed bug reporting, peaking in august and reaching a ...201424605452
group living accelerates bed bug (hemiptera: cimicidae) development.for many insect species, group living provides physiological and behavioral benefits, including faster development. bed bugs (cimex lectularius l.) live in aggregations composed of eggs, nymphs, and adults of various ages. our aim was to determine whether bed bug nymphs reared in groups develop faster than solitary nymphs. we reared first instars either in isolation or in groups from hatching to adult emergence and recorded their development time. in addition, we investigated the effects of grou ...201424605482
the eyelid sign: a clue to bed bug bites.in pediatric patients, determining the culprit insect in arthropod assaults can be challenging. the patient's history may be vague, the causative insect may not be readily associated with the bites, and the clinical appearance of bites can be variable. six pediatric patients from the penn state milton s. hershey medical center dermatology offices with bed bug bites were identified. all had bites involving the face, trunk, and extremities. five patients demonstrated papules on one upper eyelid as ...201424649832
lifting the sheets. preventing and managing health care bed bug problems. 201424665557
good night, sleep tight, don't let the bed bugs bite. 201424749219
an outbreak of bed bug infestation in an office building.since 2000, resurgence in bed bugs has occurred in the u.s. reports of infestations of homes, hospitals, hotels, and offices have been described. on september 1, 2011, complaints of itching and bites among workers in an office were reported to the tennessee department of health. a retrospective cohort study and environmental assessments were performed in response to the complaints. canines certified to detect live bed bugs were used to inspect the office and arthropod samples were collected. of ...201424749221
biochemical and toxicological properties of two acetylcholinesterases from the common bed bug, cimex lectularius.we examined the molecular and enzymatic properties of two acetylcholinesterases (aches; clache1 and clache2) from the common bed bug, cimex lectularius. native polyacrylamide gel electrophoresis followed by activity staining and western blotting revealed that clache1 is the main catalytic enzyme and is abundantly expressed in various tissues. both claches existed in dimeric form connected by a disulfide bridge and were attached to the membrane via a glycophosphatidylinositol anchor. to determine ...201424759047
[the worldwide expansion of bed bugs also constitutes a problem in germany].worldwide, reports of the spread of the bed bugs cimex lectularius and c. hemipterus (in australia) are increasing. irrespective of hygiene conditions, the insects can be especially found in hotels and hostels as well as in other holiday accommodation, health facilities, transport and in the secondhand trade. from these localities the insects spread to private households. a bed bug infestation may well have health consequences and constitutes a heavy burden for those affected. the global spread ...201424781909
a door-to-door survey of bed bug (cimex lectularius) infestations in row homes in philadelphia, pennsylvania.we conducted a door-to-door survey in a residential census tract of philadelphia to estimate the prevalence and spatial patterns of recent bed bug infestations. we interviewed 596 residents, of whom 66 (11.1%) reported recent bed bug infestations. we confirmed current infestations in a subset of 15 (68.2%) of 22 inspected households. most residents reported that their infestation began within the past year (2012-2013). we found no correlation between property value and infestation status. spatia ...201424799372
antennal olfactory sensilla responses to insect chemical repellents in the common bed bug, cimex lectularius.populations of the common bed bug cimex lectularius (hemiptera; cimicidae), a temporary ectoparasite on both humans and animals, have surged in many developed countries. similar to other haematophagous arthropods, c. lectularius relies on its olfactory system to detect semiochemicals in the environment, including both attractants and repellents. to elucidate the olfactory responses of the common bed bug to commonly used insect chemical repellents, particularly haematophagous repellents, we inves ...201424817385
evolutionary origin of insect-wolbachia nutritional mutualism.obligate insect-bacterium nutritional mutualism is among the most sophisticated forms of symbiosis, wherein the host and the symbiont are integrated into a coherent biological entity and unable to survive without the partnership. originally, however, such obligate symbiotic bacteria must have been derived from free-living bacteria. how highly specialized obligate mutualisms have arisen from less specialized associations is of interest. here we address this evolutionary issue by focusing on an ex ...201424982177
effect of feeding status on mortality response of adult bed bugs (hemiptera: cimicidae) to some insecticide products.fresh and aged residual deposits of several insecticide products were tested against bed bug adults to determine if a recent bloodmeal affected their mortality response to the residues. the bed bugs with a recent bloodmeal survived significantly longer compared with the unfed ones on their exposure to fresh or aged residual deposits of chlorfenapyr and aged residual deposits of deltamethrin on a wooden substrate. even though the survival time of fed bed bugs was significantly longer than that of ...201425026684
development of multifunctional metabolic synergists to suppress the evolution of resistance against pyrethroids in insects that blood feed on humans.pyrethroids are the insecticides of choice when exposure to humans is likely, such as occurs in vector and public-health-related control programs. unfortunately, the pyrethroids share a common resistance mechanism with dichlorodiphenyltrichloroethane (ddt), knockdown resistance (kdr), and prior extensive use of ddt has predisposed the pyrethroids to cross-resistance via kdr. given the widespread occurrence of kdr, the use of synergists with pyrethroids is considered to be prudent to guard agains ...201525044360
detection of knockdown resistance mutations in the common bed bug, cimex lectularius (hemiptera: cimicidae), in australia.pyrethroid resistance in the common bed bug, cimex lectularius l., has been reported worldwide. an important resistance mechanism is via knockdown resistance (kdr) mutations, notably v419l and l925i. information regarding this kdr-type resistance mechanism is unknown in australia. this study aims to examine the status of kdr mutations in australian c. lectularius strains.201525046700
identification of putative kdr mutations in the tropical bed bug, cimex hemipterus (hemiptera: cimicidae).bed bugs [both cimex hemipterus (f.) and cimex lectularius l.] are highly resistant to pyrethroids worldwide. an important resistance mechanism known as 'knockdown resistance' (kdr) is caused by genetic point mutations on the voltage-gated sodium channel (vgsc) gene. previous studies have identified two point mutations (v419l and l925i) on the vgsc gene in c. lectularius that are responsible for kdr-type resistance. however, the kdr mutations in c. hemipterus have not been investigated.201525132449
cutaneous reactions to bed bug bites. 201425134309
fumigation of bed bugs (hemiptera: cimicidae): effective application rates for sulfuryl fluoride.the bed bug, cimex lectularius l. (hemiptera: cimicidae), has resurged recently as a domestic pest in north america with very limited options for decisive control. we report efficacy studies with sulfuryl fluoride (sf) toward use as a structural fumigant to control bed bugs. laboratory studies were conducted in which eggs, adults, and nymphs from a pesticide susceptible laboratory population were fumigated for 24 h using sf at 99.8% purity in airtight, 3.8-liter glass containers under two temper ...201425195451
[bed bugs bites]. 201525261919
survival and fecundity of two strains of cimex lectularius (hemiptera: heteroptera).knowledge of development of the bed bug cimex lectularius l. (hemiptera: heteroptera) under specific environmental conditions could lead to improved management techniques. developmental rates, age-, and stage-specific life tables were compared for a laboratory strain and a field strain of bed bugs reared on human blood. both strains were then crossed reciprocally to produce four f1 generations and subsequent age- and stage-specific life tables were constructed. no significant differences were fo ...201425276919
bed bugs are back and also arriving is the southernmost record of cimex lectularius (heteroptera: cimicidae) in south america.the arrival and establishment of the bed bug cimex lectularius l., 1755 in magallanes region (chile) is reported. the present record is the southernmost for this species in america. the circumstances that provided for the species reaching this southern locality are discussed.201425276939
bed bugs (cimex lectularius) as vectors of trypanosoma cruzi.populations of the common bed bug, cimex lectularius, have recently undergone explosive growth. bed bugs share many important traits with triatomine insects, but it remains unclear whether these similarities include the ability to transmit trypanosoma cruzi, the etiologic agent of chagas disease. here, we show efficient and bidirectional transmission of t. cruzi between hosts and bed bugs in a laboratory environment. most bed bugs that fed on experimentally infected mice acquired the parasite. a ...201525404068
the odorant receptor co-receptor from the bed bug, cimex lectularius l.recently, the bed bug, cimex lectularius l. has re-emerged as a serious and growing problem in many parts of the world. presence of resistant bed bugs and the difficulty to eliminate them has renewed interest in alternative control tactics. similar to other haematophagous arthropods, bed bugs rely on their olfactory system to detect semiochemicals in the environment. previous studies have morphologically characterized olfactory organs of bed bugs' antenna and have physiologically evaluated the r ...201425411789
bed bug aggregation pheromone finally identified.bed bugs have become a global epidemic and current detection tools are poorly suited for routine surveillance. despite intense research on bed bug aggregation behavior and the aggregation pheromone, which could be used as a chemical lure, the complete composition of this pheromone has thus far proven elusive. here, we report that the bed bug aggregation pheromone comprises five volatile components (dimethyl disulfide, dimethyl trisulfide, (e)-2-hexenal, (e)-2-octenal, 2-hexanone), which attract ...201525529634
bed bugs.the term bed bug is applied to 2 species of genus cimex: lectularius describes the common or temperate bed bug, and hemipterus its tropical cousin. cimex lectularius is aptly named; its genus and species derive from the latin words for bug and bed, respectively. though the tiny pest is receiving increased public attention and scrutiny, the bed bug is hardly a new problem.201425577850
effects of starvation and molting on the metabolic rate of the bed bug (cimex lectularius l.).the bed bug (cimex lectularius l.) is a common hematophagous pest in the urban environment and is capable of surviving extended periods of starvation. however, the relationship between starvation and metabolism in bed bugs is not well understood. to better understand this relationship, we measured the metabolism of all life stages for >900 h after feeding (starvation) using closed-system respirometry. measurements were made around molting for the immature life stages, which occurs only after a b ...201525590593
bed bug outbreak in a neonatal unit.there has been a worldwide increase in bed bug infestations over the last 10-15 years. a major stigma is placed upon the institutions found to be infested. we report our experience with an outbreak of the tropical bed bug, cimex hemipterus, in a neonatal unit. the outbreak not only affected the admitted newborns and mothers by causing a wide variety of rashes and inducing sleeplessness, but also impinged upon the health professionals and their families by producing similar symptomology. it is im ...201525591490
dermoscopy is useful for bed bug (cimex lectularius) bites. 201625600584
[bed bug alarm in berlin. "the ignorance of people contributes to the spread"]. 201425608392
host association drives genetic divergence in the bed bug, cimex lectularius.genetic differentiation may exist among sympatric populations of a species due to long-term associations with alternative hosts (i.e. host-associated differentiation). while host-associated differentiation has been documented in several phytophagus insects, there are far fewer cases known in animal parasites. the bed bug, cimex lectularius, a wingless insect, represents a potential model organism for elucidating the processes involved in host-associated differentiation in animal parasites with r ...201525611460
evaluation of a model community-wide bed bug management program in affordable housing.low-income apartment communities in the united states are suffering from disproportionally high bed bug, cimex lectularius l., infestations owing to lack of effective monitoring and treatment. studies examining the effectiveness of integrated pest management (ipm) for the control of bed bugs in affordable housing have been limited to small subsets of bed-bug-infested apartments, rather than at the apartment community level. we developed, implemented and evaluated a complex-wide ipm program for b ...201625644070
ectoparasites of medical and veterinary importance: drug resistance and the need for alternative control methods.despite multiple attempts at eradication, many ectoparasites of humans and domestic livestock remain a persistent problem in the modern world. for many years, a range of pesticide drugs including organophosphates, organochlorides and synthetic pyrethroids provided effective control of these parasites; but intensive use of these drugs has led to the evolution of resistance in many target species. this paper aims to review the effectiveness of current control methods and discuss potential alternat ...201525644683
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