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occurrences of gastrointestinal parasites in fecal samples from domestic dogs in são paulo, sp, brazil.occurrences of gastrointestinal parasites were assessed in fecal samples from 3,099 dogs in the metropolitan region of são paulo, sp, that were treated at the veterinary hospital of the university of são paulo veterinary school. the samples were analyzed using the flotation and centrifugal sedimentation methods. the results were compared with those from previous studies (at different times). the frequency of each parasite was correlated with the dogs' ages, breeds and gender, as well as the occu ...201627925072
electrophysiology in fisher syndrome.fisher syndrome (fs), a variant of guillain-barré syndrome (gbs), is characterized by the clinical triad of ophthalmoplegia, ataxia, and areflexia. the lesion sites for these unique clinical features include the oculomotor nerves and group 1a neurons in the dorsal root ganglion, and the presence of fs is determined by the expression of ganglioside gq1b in the human nervous system. neurophysiological findings suggest that ataxia and areflexia are due to an impaired proprioceptive afferent system. ...201727923188
study of the chemical space of selected bacteriostatic sulfonamides from an information theory point of view.the relative structural location of a selected group of 27 sulfonamide-like molecules in a chemical space defined by three information theory quantities (shannon entropy, fisher information, and disequilibrium) is discussed. this group is composed of 15 active bacteriostatic molecules, 11 theoretically designed ones, and para-aminobenzoic acid. this endeavor allows molecules that share common chemical properties through the molecular backbone, but with significant differences in the identity of ...201627922225
world endometriosis society consensus on the classification of endometriosis.what is the global consensus on the classification of endometriosis that considers the views of women with endometriosis?201727920089
longitudinal beta-binomial modeling using gee for overdispersed binomial data.longitudinal binomial data are frequently generated from multiple questionnaires and assessments in various scientific settings for which the binomial data are often overdispersed. the standard generalized linear mixed effects model may result in severe underestimation of standard errors of estimated regression parameters in such cases and hence potentially bias the statistical inference. in this paper, we propose a longitudinal beta-binomial model for overdispersed binomial data and estimate th ...201727917499
[pathophysiology of ataxia in fisher syndrome].fisher syndrome is regarded as a peculiar inflammatory neuropathy associated with ophthalmoplegia, ataxia, and areflexia. the disorder is associated with preceding infection, cerebrospinal fluid albumino-cytological dissociation, and spontaneous recovery, and regarded as a variant of guillain-barré syndrome. the discovery of anti-gq1b igg antibodies led to dramatic advances in understanding the pathophysiology of fisher syndrome. the lesions in fisher syndrome are determined by expression of gan ...201627916750
[lung transplantation for phase ⅲ silicosis: a series of 32 cases].objective: to evaluate the effect of lung transplantation for phase ⅲ silicosis. methods: from september 2002 to september 2015, 32 patients with end-stage silicosis underwent lung transplantation at department of thoracic surgery, affiliated wuxi people's hospital, nanjing medical university. there were 29 male and 3 female patients aged from 24 to 63 years. thirty-two patients were diagnosed as phase ⅲ silicosis by the local occupational disease prevention and control center. fifteen patients ...201627916032
lacrimal gland involvement in blepharophimosis-ptosis-epicanthus inversus syndrome.to describe the involvement of the lacrimal gland (lg) in blepharophimosis-ptosis-epicanthus inversus syndrome (bpes).201727914838
demographic and clinical characteristics of a predominantly hispanic population with inflammatory bowel disease on the us-mexico border.information regarding hispanics with inflammatory bowel disease (ibd) is scarce. in this study we aimed to describe a predominantly hispanic population with ibd in a city located along the us-mexico border and to identify clinical or demographic differences between hispanics and non-hispanics.201627911976
diagnostic accuracy of faecal biomarkers in detecting colorectal cancer and adenoma in symptomatic patients.the diagnosis of colorectal cancer (crc) can be difficult as symptoms are variable with poor specificity. thus, there is a quest for simple, non-invasive testing that can help streamline those with significant colonic pathology.201727910113
experiment design for nonparametric models based on minimizing bayes risk: application to voriconazole[formula: see text].an experimental design approach is presented for individualized therapy in the special case where the prior information is specified by a nonparametric (np) population model. here, a np model refers to a discrete probability model characterized by a finite set of support points and their associated weights. an important question arises as to how to best design experiments for this type of model. many experimental design methods are based on fisher information or other approaches originally devel ...201727909942
comparison of two different enteral nutrition protocol in critically ill patients.in this study, two enteral nutrition protocols with different gastric residual volumes (grvs) and different monitoring intervals were compared with respect to gastrointestinal intolerance findings in intensive care unit (icu) patients.201627909608
classification and verification of handwritten signatures with time causal information theory quantifiers.we present a new approach for handwritten signature classification and verification based on descriptors stemming from time causal information theory. the proposal uses the shannon entropy, the statistical complexity, and the fisher information evaluated over the bandt and pompe symbolization of the horizontal and vertical coordinates of signatures. these six features are easy and fast to compute, and they are the input to an one-class support vector machine classifier. the results are better th ...201627907014
computed tomographic analysis: the effects of frontal recess morphology and the presence of anatomical variations on frontal sinus pneumatization.the aim of this study is to describe the morphology of frontal recess area with its anatomical variations and to reveal if frontal recess morphology and the anatomical variations related to that region have effects on the pneumatization of the frontal sinuses. the frontal sinus and recess morphometry of 136 sides of 68 dry skulls were evaluated on multislice high-resolution computed tomography. the relationships between frontal sinus and frontal recess measurements were analyzed by correlation a ...201727906846
hemodynamic disturbances in the early phase after subarachnoid hemorrhage: regional cerebral blood flow studied by bedside xenon-enhanced ct.the mechanisms leading to neurological deterioration and the devastating course of delayed cerebral ischemia (dci) after subarachnoid hemorrhage (sah) are still not well understood. bedside xenon-enhanced computerized tomography (xect) enables measurements of regional cerebral blood flow (rcbf) during neurosurgical intensive care. in the present study, cbf characteristics in the early phase after severe sah were explored and related to clinical characteristics and early clinical course outcome.201627906765
transient bone marrow edema syndrome versus osteonecrosis: perfusion patterns at dynamic contrast-enhanced mr imaging with high temporal resolution can allow differentiation.purpose to prospectively evaluate the perfusion patterns at quantitative dynamic contrast material-enhanced (dce) magnetic resonance (mr) imaging of transient bone marrow edema syndrome (tbmes) and avascular osteonecrosis. materials and methods institutional review board approval and written informed consent were obtained. thirty-two patients (21 men, 11 women; mean age, 48 years; 26 hips, 10 knees) underwent conventional mr imaging and a dynamic contrast-enhanced three-dimensional spoiled gradi ...201727905865
factors associated to post-operative nausea and vomiting following oral and maxillofacial surgery: a prospective study.this study aims to address and assess possible factors associated with nausea and vomiting (nv) following oral and maxillofacial surgery.201727904962
virtual reality and anxiety in primiparous women during episiotomy repair.in recent studies, using virtual reality (vr) has been proposed as a nonpharmacological method for anxiety reduction, but until this time, its effects have not been assessed on anxiety during episiotomy repair. this study aimed to determine the effect of audiovisual distraction (vr) on anxiety in primiparous women during episiotomy repair.201727904638
[current status of warfarin therapy in chinese patients with nonvalvular atrial fibrillation: a single center analysis].objective: to investigate the current status of warfarin therapy and the related factors in patients with nonvalvular atrial fibrillation(nvaf) based on data from a single center. methods: we analyzed clinical data including baseline clinical characteristics, complications, concomitant medications and anti-thrombotic treatment in patients who were admitted to our hospital with nvaf from january 2014 to june 2014. the data were analyzed by t test, chi-square test, fisher exact test and binary log ...201627903391
predicting neurological deficit severity due to subarachnoid haemorrhage: soluble cd40 ligand and platelet-derived growth factor-bb.several biological markers can predict outcomes in patients with subarachnoid haemorrhage (sah), but markers to predict neurological deficit severity in patients with sah and poor neurological condition have not yet been established. soluble cd40 ligand (scd40l) and platelet-derived growth factor (pdgf) are related to the systemic inflammatory response.201627903205
outcomes in transcranial microsurgery versus extended endoscopic endonasal approach for primary resection of adult craniopharyngiomas.objective craniopharyngiomas have historically been resected via transcranial microsurgery (tcm). in the last 2 decades, the extended endoscopic endonasal (transtuberculum) approach to these tumors has become more widely accepted, yet there remains controversy over which approach leads to better outcomes. the purpose of this study is to determine whether differences in outcomes were identified between tcm and extended endoscopic endonasal approaches (eeeas) in adult patients undergoing primary r ...201627903125
effect of nerve stimulation use on the success rate of ultrasound-guided subsartorial saphenous nerve block: a randomized controlled trial.ultrasound-guided subsartorial saphenous nerve block is commonly used to provide complete surgical anesthesia of the foot and ankle in combination with a popliteal sciatic nerve block. however, in part owing to its small caliber and absence of a prominent vascular landmark in the subsartorial plane distal to the adductor canal, the saphenous nerve is more difficult to reliably block than the sciatic nerve in the popliteal fossa. although the saphenous nerve is a sensory nerve only, neurostimulat ...201727902645
prosthetic design of reverse shoulder arthroplasty contributes to scapular notching and instability.to evaluate whether implant design, glenoid positioning, and other factors influenced instability and scapular notching in reverse total shoulder arthroplasty.201627900271
motivations and predictors of cheating in pharmacy school.objective. to assess the prevalence, methods, and motivations for didactic cheating among pharmacy students and to determine predictive factors for cheating in pharmacy colleges and schools. methods. a 45-item cross-sectional survey was conducted at all four doctor of pharmacy programs in northern california. for data analysis, t test, fisher exact test, and logistic regression were used. results. overall, 11.8% of students admitted to cheating in pharmacy school. primary motivations for cheatin ...201627899829
reducing unplanned extubations in the nicu using lean methodology.unplanned extubations can lead to iatrogenic injury and have the potential to contribute to serious safety events. we adopted lean methodology to reduce the unplanned extubation rate in a level 3b nicu. we hypothesized that the use of a rapid-cycle pdsa (plan, do, study, act) initiative would reduce the unplanned extubation rate.201627899538
the fragility of statistically significant findings from randomized trials in sports surgery: a systematic survey.high-quality, evidence-based orthopaedic care relies on the generation and translation of robust research evidence. the fragility index is a novel method for evaluating the robustness of statistically significant findings from randomized controlled trials (rcts). it is defined as the minimum number of patients in 1 arm of a trial that would have to change status from a nonevent to an event to alter the results of the trial from statistically significant to nonsignificant.201727895038
apneic oxygenation may not prevent severe hypoxemia during rapid sequence intubation: a retrospective helicopter emergency medical service study.this study sought to determine the effectiveness of apneic oxygenation in preventing hypoxemia during prehospital rapid sequence intubation (rsi).201727894561
allele specific-pcr and melting curve analysis showed relatively high frequency of β-casein gene a1 allele in iranian holstein, simmental and native cows.there are two allelic forms of a1 and a2 of β-casein gene in dairy cattle. proteolytic digestion of bovine β-casein a1 type produces bioactive peptide of β-casomorphin-7 known as milk devil. β-casomorphin-7 causes many diseases, including type 1 diabetes, cardiovascular disease syndrome, sudden death and madness. the aim of the present study was to determine the different allelic forms of β-casein gene in iranian holstein, simmental and native cattle in order to identify a1 and a2 variants. the ...201627894411
the impact of prescriptions on sex partner treatment using expedited partner therapy for chlamydia trachomatis infection, new york city, 2014-2015.chlamydia trachomatis reinfections, often resulting from resuming sex with untreated partners, can increase the risk of pelvic inflammatory disease, infertility, and ectopic pregnancy. expedited partner therapy (ept) has been shown to prevent reinfection when provided as medication (medication-ept) that patients give to sex partners; however, ept is often provided as a prescription (prescription-ept). we compared partner treatment outcomes for medication-ept versus prescription-ept.201627893595
human papillomavirus-induced oropharyngeal cancer in hispanics in the united states.determine disparities in survival outcome and clinical presentation between hispanic and non-hispanic white patients with human papillomavirus-positive oropharyngeal squamous cell carcinoma.201627891616
urban rural comparison of anthropometry and menarcheal status of adolescent school going girls of jodhpur, rajasthan, india.adolescence is the formative period of life. poor adolescent health translates into poor maternal health leading to increased maternal morbidity with inter-generational consequences.201627891415
a comparative study of single incision versus conventional four ports laparoscopic cholecystectomy.cholelithiasis is one of the most common disorders of the digestive tract encountered by general surgeons worldwide. conventional or open cholecystectomy was the mainstay of treatment for a long time for this disease. in the 1980s laparoscopic surgery revolutionized the management of biliary tract diseases. it brought about a revolutionary change in the basic concepts of surgical principles and minimal access surgery gradually started to be acknowledged as a safe means of carrying out surgeries.201627891389
case-control study of diarrheal disease etiology in individuals over 5 years in southwest china.acute diarrhea is one of the major public health problems worldwide. most of studies on acute diarrhea have been made on infants aged below 5 years and few efforts have been made to identify the etiological agents of acute diarrhea in people over five, especially in china.201627891182
reinforced angle-based multicategory support vector machines.the support vector machine (svm) is a very popular classification tool with many successful applications. it was originally designed for binary problems with desirable theoretical properties. although there exist various multicategory svm (msvm) extensions in the literature, some challenges remain. in particular, most existing msvms make use of k classification functions for a k-class problem, and the corresponding optimization problems are typically handled by existing quadratic programming sol ...201627891045
predictors of shunt insertion in aneurysmal subarachnoid hemorrhage.hydrocephalus is a common complication of aneurysmal subarachnoid hemorrhage (asah), requiring permanent cerebrospinal fluid (csf) diversion in up to two thirds of patients. factors that predict permanent csf diversion are not well established.201727890755
acute disseminated encephalomyelitis following campylobacter jejuni gastroenteritis: case report and review of the literature.we describe a case of a 25-year-old male with a diagnosis of acute disseminated encephalomyelitis (adem) following infection with campylobacter jejuni, which is implicated in various human pathologies regarding the central nervous system (cns) with acute course like guillain-barré syndrome (gbs), miller-fisher syndrome (mfs), bickerstaff's brainstem encephalitis (bee), acute transverse myelitis (atm) as well as adem. these conditions are caused by cross-reactivity between campylobacter's epitope ...201727888275
phosphoramide mustard induces autophagy markers and mtor inhibition prevents follicle loss due to phosphoramide mustard exposure.phosphoramide mustard (pm) is an ovotoxic metabolite of cyclophosphamide. postnatal day 4 fisher 344 rat ovaries were exposed to vehicle control (1% dmso) or pm (60μm)±ly294002 or rapamycin for 2 or 4 d. transmission election microscopy revealed abnormally large golgi apparatus and electron dense mitochondria in pm-exposed ovaries prior to and at the time of follicle depletion. pm exposure increased (p<0.05) mrna abundance of bbc3, cdkn1a, ctfr, edn1, gstp1, nqo1, tlr4, tnfrsfla, txnrd1 and decr ...201727888070
significant regional variation exists in morbidity and mortality after repair of abdominal aortic aneurysm.limited data exist comparing perioperative morbidity and mortality after open and endovascular abdominal aortic aneurysm (aaa) repair (evar) among regions of the united states. this study evaluated the regional variation in mortality and perioperative outcomes after repair of aaas.201727887854
parameter set for computer-assisted texture analysis of fetal brain.magnetic resonance data were collected from a diverse population of gravid women to objectively compare the quality of 1.5-tesla (1.5 t) versus 3-t magnetic resonance imaging of the developing human brain. mazda and b11 computational-visual cognition tools were used to process 2d images. we proposed a wavelet-based parameter and two novel histogram-based parameters for fisher texture analysis in three-dimensional space.201627887658
a computer tool for a minimax criterion in binary response and heteroscedastic simple linear regression models.binary response models are used in many real applications. for these models the fisher information matrix (fim) is proportional to the fim of a weighted simple linear regression model. the same is also true when the weight function has a finite integral. thus, optimal designs for one binary model are also optimal for the corresponding weighted linear regression model. the main objective of this paper is to provide a tool for the construction of mv-optimal designs, minimizing the maximum of the v ...201727886709
histogram-based feature extraction from individual gray matter similarity-matrix for alzheimer's disease classification.automatic computer-aided diagnosis (cad) systems have been widely used in classification of patients who suffer from alzheimer's disease (ad). this paper presents an automatic cad system based on histogram feature extraction from single-subject gray matter similarity-matrix for classifying the ad patients from healthy controls (hc) using structural magnetic resonance imaging (mri) data. the proposed cad system is composed of five stages. in the first stage, segmentation is employed to perform pr ...201727886012
cxc chemokine receptor 4 (cxcr4) antagonist, a novel pathway to prevent chronic allograft nephropathy.background chronic allograft nephropathy (can) remains a major problem for long-term graft survival and different pathways participate in its development. cxc chemokine receptor 4 (cxcr4) is significantly upregulated following renal injury and fibrotic response. we investigated the effect of amd3100, a cxcr4 antagonist, on the development of can in rat models. material and methods can rat models (n=20) were established using male fisher 344 to lewis rats. rats in the experimental group (n=10) we ...201627885250
the consequences of landscape change on fishing strategies.we show how land-use change can affect fisher-harvesting behavior. we test whether fisher harvesting behavior can be predicted by landscape change patterns at local (~200km) and regional (~1200km) levels. our data suggest that fishers harvesting in areas near tree plantations reduced benthic-invertebrate harvests in favor of demersal and pelagic finfish that are usually located further offshore. fishers' management areas, which were near tree plantations, had higher chlorophyll-a values, and con ...201727884521
enhanced expression of the stemness-related factors oct4, sox15 and twist1 in ectopic endometrium of endometriosis patients.current evidence suggests that endometrial-derived stem cells, spilled in the peritoneal cavity via retrograde menstruation, are key players in the establishment of endometriotic lesions. the aim of this study was to determine the presence and distribution of the stemness-related factors oct4, sox15, twist1 and dcamlk1 in women with and without endometriosis.201627881125
composite sickles and cereal harvesting methods at 23,000-years-old ohalo ii, israel.use-wear analysis of five glossed flint blades found at ohalo ii, a 23,000-years-old fisher-hunter-gatherers' camp on the shore of the sea of galilee, northern israel, provides the earliest evidence for the use of composite cereal harvesting tools. the wear traces indicate that tools were used for harvesting near-ripe semi-green wild cereals, shortly before grains are ripe and disperse naturally. the studied tools were not used intensively, and they reflect two harvesting modes: flint knives hel ...201627880839
the effects of migration and assortative mating on admixture linkage disequilibrium.statistical models in medical and population genetics typically assume that individuals assort randomly in a population. while this simplifies model complexity, it contradicts an increasing body of evidence of nonrandom mating in human populations. specifically, it has been shown that assortative mating is significantly affected by genomic ancestry. in this work, we examine the effects of ancestry-assortative mating on the linkage disequilibrium between local ancestry tracks of individuals in an ...201727879348
microrna-6826 and -6875 in plasma are valuable non‑invasive biomarkers that predict the efficacy of vaccine treatment against metastatic colorectal cancer.various vaccine treatments against metastatic colorectal cancer have been developed and applied. however, to improve the efficacy of immunotherapy, biomarkers that can predict the effects are needed. it has been reported that various micrornas (mirnas) in peripheral blood may be useful as non-invasive biomarkers. in this study, mirnas influencing the efficacy of vaccine treatment were screened for in a microarray analysis of 13 plasma samples that were obtained from patients prior to vaccine tre ...201727878288
arthroscopic subscapularis augmentation of bankart repair in chronic anterior shoulder instability with bone loss less than 25% and capsular deficiency: clinical multicenter study.to assess the short-term outcomes of the arthroscopic subscapularis augmentation (asa) technique, consisting of a tenodesis of the upper third of the subscapularis tendon and a bankart repair, and its effect on shoulder external rotation.201727876488
the risk of melanoma and hematologic cancers in patients with psoriasis.the risk of melanoma and hematologic cancers in patients with psoriasis is controversial.201727876302
a discriminant analysis prediction model of non-syndromic cleft lip with or without cleft palate based on risk factors.a risk prediction model of non-syndromic cleft lip with or without cleft palate (nscl/p) was established by a discriminant analysis to predict the individual risk of nscl/p in pregnant women.201627876010
a case of miller fisher syndrome associated with preceding herpes zoster ophthalmicus. 201727875624
locally-supervised deep hybrid model for scene recognition.convolutional neural networks (cnn) have recently achieved remarkable successes in various image classification and understanding tasks. the deep features obtained at the top fully-connected layer of the cnn (fc-features) exhibit rich global semantic information and are extremely effective in image classification. on the other hand, the convolutional features in the middle layers of the cnn also contain meaningful local information, but are not fully explored for image representation. in this pa ...201627875222
aneurysm rebleeding after poor-grade aneurysmal subarachnoid hemorrhage: predictors and impact on clinical outcomes.aneurysm rebleeding is a major cause of morbidity and mortality after aneurysmal subarachnoid hemorrhage (asah) and more often occurs in patients with poor-grade asah. limited data on predictors of rebleeding in these patients are available.201627871451
breast cancers found with digital breast tomosynthesis: a comparison of pathology and histologic grade.to compare the pathology and histologic grading of breast cancers detected with digital breast tomosynthesis to those found with conventional digital mammography. the institutional review board approved this study. a database search for all breast cancers diagnosed from june 2012 through december 2013 was performed. imaging records for these cancers were reviewed and patients who had screening mammography with tomosynthesis as their initial examination were selected. five dedicated breast imagin ...201627870337
patterns of reflux in gastroesophageal reflux disease in pediatric population of new south wales.this study is to determine the association of ambulatory ph monitoring (24hr ph) with symptoms of gastroesophageal reflux and its other investigations. the clinical and epidemiological profiles of subjects referred for reflux disorders are also studied. symptoms or group of symptoms, profiles and prior investigations of 1259 consecutive pediatric subjects (with 1332 24hr ph studies performed) referred for evaluation of reflux disorders between 1988 and 2012 were retrospectively studied. chi-squa ...201727868292
prkag3 polymorphisms associated with sporadic wolff-parkinson-white syndrome among a taiwanese population.the aim of this study was to investigate whether mutation in amp-activated protein kinase (ampk) subunit genes (prkag3-230) is associated with sporadic, isolated wolff-parkinson-white (wpw) syndrome.201627866917
n-[(11)ch3]dimethylaminoparthenolide (dmapt) uptake into orthotopic 9lsf glioblastoma tumors in the rat.the aim of this study was to determine the uptake of intravenously administered n-[(11)ch3]-dimethylaminoparthenolide (dmapt) into orthotopic 9lsf glioblastoma brain tumors in fisher 344 rats from positron emission tomography (pet) imaging studies. [(11)c]methyl iodide ((11)ch3i) was utilized as a [(11)c]-labeling reagent to label the precursor methylaminoparthenolide (mapt) intermediate. from pet imaging studies it was found that brain uptake of n-[(11)ch3]dmapt into brain tumor tissue was rapi ...201627866815
optimizing the success of surgeons innovating and commercializing ideas: 10 lessons learned.michael blackhurst is a salaried employee in the role of general manager of the surgical product group of fisher and paykel healthcare limited.201627866641
[a fisher discriminant model to predict the outcome of postoperative blood pressure in primary aldosteronism].objective: to establish a fisher discriminant model in order to predict the outcome of postoperative blood pressure for primary aldosteronism (pa). methods: a total of 83 cases from the first affiliated hospital of chongqing medical university were enrolled and divided into two groups: cure group and not cure group according to postoperative blood pressure. fisher stepwise discriminant analysis was used to establish a discriminant model, and compared with aldosteronoma resolution score (ars) and ...201627866529
fixation probability in a haploid-diploid population.classical population genetic theory generally assumes either a fully haploid or fully diploid life cycle. however, many organisms exhibit more complex life cycles, with both free-living haploid and diploid stages. here we ask what the probability of fixation is for selected alleles in organisms with haploid-diploid life cycles. we develop a genetic model that considers the population dynamics using both the moran model and wright-fisher model. applying a branching process approximation, we obtai ...201727866168
joint l2,1 norm and fisher discrimination constrained feature selection for rational synthesis of microporous aluminophosphates.feature selection has been regarded as an effective tool to help researchers understand the generating process of data. for mining the synthesis mechanism of microporous alpos, this paper proposes a novel feature selection method by joint l2,1 norm and fisher discrimination constraints (jnfdc). in order to obtain more effective feature subset, the proposed method can be achieved in two steps. the first step is to rank the features according to sparse and discriminative constraints. the second st ...201727863104
porous versus nonporous orbital implants after enucleation for uveal melanoma: a randomized study.to compare hydroxyapatite with acrylic implants after enucleation for uveal melanoma with respect to eyelid position, ocular motility, implant complications, and patient satisfaction.201627861329
digital subtraction of magnetic resonance images improves detection and characterization of pancreatic neuroendocrine neoplasms.the aim of this study was to evaluate the usefulness of digital image subtraction of contrast-enhanced magnetic resonance (mr) images for detection and characterization of pancreatic neuroendocrine neoplasms (pannens).201727861198
anti-gq1b ganglioside positive miller fisher syndrome - evidence of paranodal pathology on nerve biopsy.miller fisher syndrome is a regional variant of guillain-barre syndrome with a characteristic clinical triad of ophthalmoplegia, areflexia and ataxia and occasionally distal limb sensory loss. 90% of patients have associated antibodies to the gq1b ganglioside. the pathophysiology of antibody-mediated peripheral nerve impairment remains uncertain. this report includes the first description of a peripheral sensory nerve biopsy in miller fisher syndrome.201427858774
diagnostic utility of auto antibodies in inflammatory nerve disorders.a wide range of autoantibodies have been described in immune-mediated nerve disorders that target glycans borne by glycolipids and glycoproteins enriched in the peripheral nerves. their use as diagnostic biomarkers is very widespread, despite some limitations on sensitivity and specificity, and the lack of standardized assays and access to quality assurance schemes. although many methods have been applied to measurement, elisa, in the form of commercial kits or in-house assays, still remains the ...201527858733
the clinical predictors of shunt-dependent hydrocephalus following aneurysmal subarachnoid hemorrhage.shunt-dependent hydrocephalus (sdh) is a relatively common complication following aneurysmal subarachnoid hemorrhage (asah). delay in diagnosis and treatment may worsen neurological outcome. this study was conducted to identify early clinical factors associated with sdh following asah.201627858393
statistical inference in abstracts of major medical and epidemiology journals 1975-2014: a systematic review.since its introduction in the twentieth century, null hypothesis significance testing (nhst), a hybrid of significance testing (st) advocated by fisher and null hypothesis testing (nht) developed by neyman and pearson, has become widely adopted but has also been a source of debate. the principal alternative to such testing is estimation with point estimates and confidence intervals (ci). our aim was to estimate time trends in nhst, st, nht and ci reporting in abstracts of major medical and epide ...201727858205
efficacy of double-blind peer review in an imaging subspecialty journal.many scientific journals use double-blind peer review to minimize potential reviewer bias concerning publication recommendations. however, because neuroradiology is a relatively small subspecialty, this process may be limited by prior knowledge of the authors' work or associated institutions. we sought to investigate the efficacy of reviewer blinding and determine the impact that unblinding may have on manuscript acceptance.201727856433
computer-aided detection of pulmonary nodules using dynamic self-adaptive template matching and a flda classifier.improving the performance of computer-aided detection (cad) system for pulmonary nodules is still an important issue for its future clinical applications. this study aims to develop a new cad scheme for pulmonary nodule detection based on dynamic self-adaptive template matching and fisher linear discriminant analysis (flda) classifier. we first segment and repair lung volume by using otsu algorithm and three-dimensional (3d) region growing. next, the suspicious regions of interest (rois) are ext ...201627856118
distribution of bottom trawling effort in the yellow sea and east china sea.bottom trawling is one of the most efficient fishing activities, but serious and persistent ecological issues have been observed by fishers, scientists and fishery managers. although china has applied the beidou fishing vessel position monitoring system (vms) to manage trawlers since 2006, little is known regarding the impacts of trawling on the sea bottom environments. in this study, continuous vms data of the 1403 single-rig otter trawlers registered in the xiangshan port, 3.9% of the total tr ...201627855215
fisheries regulatory regimes and resilience to climate change.climate change is already producing ecological, social, and economic impacts on fisheries, and these effects are expected to increase in frequency and magnitude in the future. fisheries governance and regulations can alter socio-ecological resilience to climate change impacts via harvest control rules and incentives driving fisher behavior, yet there are no syntheses or conceptual frameworks for examining how institutions and their regulatory approaches can alter fisheries resilience to climate ...201727854068
the effect of obesity on the improvement in health state outcomes following minimally invasive transforaminal interbody fusion.study design observational study. objective studies have shown a correlation between obesity and lumbar spine pathology, but also that obese patients have higher rates of complication following lumbar spine surgery. it is unknown if obese patients have clinical gains following lumbar spine surgery comparable to the gain of normal-weight patients. this study investigated the correlation of obesity and the delta change in outcomes in a single surgeon's cohort of normal-weight and obese patients un ...201627853657
mpc1 and mpc2 expressions are associated with favorable clinical outcomes in prostate cancer.cancer cells exhibit an altered metabolism, which is characterized by a preference for aerobic glycolysis more than mitochondrial oxidation of pyruvate. mitochondrial pyruvate carrier 1 (mpc1) and mitochondrial pyruvate carrier 2 (mpc2) play a bottleneck role by transporting pyruvate into mitochondrial through the mitochondrial inner membrane. therefore, their protein expression in cancers may be of clinical consequences. there are studies showing low levels of mpc1 expression in colon, kidney a ...201627852261
less invasive phenotype found in isocitrate dehydrogenase-mutated glioblastomas than in isocitrate dehydrogenase wild-type glioblastomas: a diffusion-tensor imaging study.purpose to explore the diffusion-tensor (dt) imaging-defined invasive phenotypes of both isocitrate dehydrogenase (idh-1)-mutated and idh-1 wild-type glioblastomas. materials and methods seventy patients with glioblastoma were prospectively recruited and imaged preoperatively. all patients provided signed consent, and the local research ethics committee approved the study. patients underwent surgical resection, and tumor samples underwent immunohistochemistry for idh-1 r132h mutations. dt imagin ...201727849434
is extended preoperative antibiotic prophylaxis for high-risk patients necessary before percutaneous nephrolithotomy?the goal of this study was to compare the rate of systemic inflammatory response syndrome (sirs) in high-risk patients undergoing percutaneous nephrolithotomy (pcnl) between patients who received 7, 2, or 0 days of preoperative antibiotics.201627847915
increased prevalence of autoimmune disease within c9 and ftd/mnd cohorts: completing the picture.to determine the prevalence of autoimmune disease in symptomatic c9orf72 (c9) mutation carriers and frontotemporal dementia with motor neuron disease (ftd/mnd) cohorts.201627844039
are intensive cares worthwhile for breast cancer patients: the experience of an oncological icu.one among seven women will present with breast cancer for which major therapeutic advances led to a significant increase in survival and cure rates. during or after cancer treatment, severe complications may occur requiring admission in intensive care unit (icu). intensivists could be reluctant for accepting cancer patients in the icu, and there are very few data about causes of admission and prognosis of patients with breast cancer admitted in the icu for an acute complication. our study seeks ...201627843912
study of efficacy and timing of laser suture lysis in reducing intraocular pressure after trabeculectomy with mitomycin-c.laser suture lysis is used to enhance filtration after trabeculectomy.201727843228
solution of classical evolutionary models in the limit when the diffusion approximation breaks down.the discrete time mathematical models of evolution (the discrete time eigen model, the moran model, and the wright-fisher model) have many applications in complex biological systems. the discrete time eigen model rather realistically describes the serial passage experiments in biology. nevertheless, the dynamics of the discrete time eigen model is solved in this paper. the 90% of results in population genetics are connected with the diffusion approximation of the wright-fisher and moran models. ...201627841654
species survival and scaling laws in hostile and disordered environments.in this work we study the likelihood of survival of single-species in the context of hostile and disordered environments. population dynamics in this environment, as modeled by the fisher equation, is characterized by negative average growth rate, except in some random spatially distributed patches that may support life. in particular, we are interested in the phase diagram of the survival probability and in the critical size problem, i.e., the minimum patch size required for surviving in the lo ...201627841634
impact of chlorhexidine bathing on methicillin-resistant staphylococcus aureus incidence in an endemic chronic care setting: a randomized controlled trial.we postulated that bathing with 2% chlorhexidine-impregnated antiseptic washcloths could reduce methicillin-resistant staphylococcus aureus (mrsa) incidence among chronic care patients compared with nonantiseptic bathing. a total of 122 patients on 3 hospital units were enrolled in a 12-month, cluster-randomized, open-label, controlled trial, with 8 patients becoming mrsa positive. the 2% chlorhexidine-impregnated antiseptic washcloths reduced incidence by 71% (0.1 vs 0.44 cases per 1,000 patien ...201727839752
cellular defects by deletion of ano10 are due to deregulated local calcium signaling.tmem16k (ano10) belongs to a family of ion channels and phospholipid scramblases. mutations in ano10 cause neurological and immunological defects, and abrogated ion transport. here we show that ano10 knockout in epithelial cells leads to defective ion transport, attenuated volume regulation and deranged ca(2+) signaling. intestinal epithelial cells from ano10 null mice are reduced in size and demonstrate an almost abolished spontaneous and tnfα-induced apoptosis. similar defects were found in mo ...201727838374
the safety and efficacy of irreversible electroporation for large hepatocellular carcinoma.this study aimed to investigate the safety and effectiveness of irreversible electroporation ablation for unresectable large liver cancer. fourteen patients were enrolled: 8 with large hepatocellular carcinoma (tumor diameter: 5.1-11.5 cm) and 6 with medium hepatocellular carcinoma (tumor diameter: 3.0-4.1 cm). all patients received percutaneous irreversible electroporation ablation. ablation time and the incidence of complications were assessed by a t test. post-irreversible electroporation and ...201727837054
the risk factors, costs, and survival analysis of invasive vre infections at a medical center in eastern taiwan.to analyze 48 cases the risk factors of vancomycin-resistant enterococcus (vre) infections, the antibiotic costs after infection, and the survival conditions.201727836794
lymphocyte depression as a predictor of postoperative intraabdominal abscess after appendectomy in children.this study evaluated the efficacy of lymphopenia to predict postappendectomy intraabdominal abscess (iaa) in pediatric complex appendicitis.201727836359
consequences of experience and specialist training on the fabrication of implant-supported prostheses: a survey.fabricating fixed restorations on implants requires that dentists stay up-to-date with the scientific publications.201727836146
prediction of endocrine system affectation in fisher 344 rats by food intake exposed with malathion, applying naïve bayes classifier and genetic algorithms.reported cases of uncontrolled use of pesticides and its produced effects by direct or indirect exposition, represent a high risk for human health. therefore, in this paper, it is shown the results of the development and execution of an algorithm that predicts the possible effects in endocrine system in fisher 344 (f344) rats, occasioned by ingestion of malathion.201627833725
ce: original research: examining the links between lifestyle factors and metabolic syndrome.: background: as it is in many other developed countries, obesity is a growing health concern in taiwan, affecting nearly 20% of the adult population. obesity can increase the risk of developing metabolic syndrome, diabetes, and cardiovascular disease. recent data indicate that the prevalence of metabolic syndrome in taiwan is 25.5%. yet some overweight and obese individuals have normal metabolic profiles. it's not clear why some overweight or obese people remain metabolically healthy while othe ...201627831954
optimal prediction of the number of unseen species.estimating the number of unseen species is an important problem in many scientific endeavors. its most popular formulation, introduced by fisher et al. [fisher ra, corbet as, williams cb (1943) j animal ecol 12(1):42-58], uses n samples to predict the number u of hitherto unseen species that would be observed if [formula: see text] new samples were collected. of considerable interest is the largest ratio t between the number of new and existing samples for which u can be accurately predicted. in ...201627830649
[tnm-classification of localized prostate cancer : the clinical t-category does not correspond to the required demands].the tnm staging system for localized prostate cancer (pca) divides tumors based on clinical parameters into a clinical (c)t category and, after radical prostatectomy (rp), a pathological (p)t category.201627830286
counseling by epileptologists affects contraceptive choices of women with epilepsy.there are several important interactions between antiepileptic drugs (aeds) and hormonal contraception that need to be carefully considered by women with epilepsy (wwe) and their practitioners. many aeds induce hepatic enzymes and decrease the efficacy of hormonal contraception. in addition, estrogen-containing hormonal contraception can increase the metabolism of lamotrigine, the most commonly prescribed aed in women of childbearing age. the intrauterine device (iud) is a highly effective form ...201627829186
alcohol use disorder as a possible predictor of electroconvulsive therapy response.two rapidly acting antidepressive treatment forms, namely, electroconvulsive therapy (ect) and ketamine, possibly share a common mechanism of action primarily involving alterations of neurotransmission (glutamate and γ-aminobutyric acid levels). because patients receiving ketamine and with a coexistent family history of an alcohol use disorder (aud) seem to benefit from consistent and longer lasting antidepressive effects, we hypothesized better treatment response in ect patients with an own his ...201727828926
rate matrix estimation from site frequency data.a procedure is described for estimating evolutionary rate matrices from observed site frequency data. the procedure assumes (1) that the data are obtained from a constant size population evolving according to a stationary wright-fisher or decoupled moran model; (2) that the data consist of a multiple alignment of a moderate number of sequenced genomes drawn randomly from the population; and (3) that within the genome a large number of independent, neutral sites evolving with a common mutation ra ...201727825765
predictors of persistent or recurrent disease after loop electrosurgical excision procedure.follow-up recommendations after an excisional procedure vary depending on whether or not there is a positive ectocervical or endocervical margin or endocervical curettage (ecc). the purpose of this study was to evaluate the importance of these findings in predicting recurrent/persistent (r/p) disease in a sample of human immunodeficiency virus (hiv)-seropositive and -negative patients.201727824789
readmission and prolapse recurrence after abdominal and vaginal apical suspensions in older women.our objective was to evaluate 30-day readmission, 12-month prolapse recurrence, and complications after apical surgeries in older women.201627824746
posterior reversible encephalopathy as the first manifestation of bickerstaff's brainstem encephalitis.posterior reversible encephalopathy syndrome (pres) has been associated with guillain-barre syndrome in rare cases. here we report a patient in whom pres was the presenting manifestation of bickerstaff's brainstem encephalitis.201627821089
comparison of clinical features and outcomes in patients with bilateral versus unilateral adrenal neuroblastoma.while nearly half of cases of neuroblastoma arise in one of the adrenal glands, bilateral origin is rare. we aimed to compare clinical characteristics and outcomes between patients with bilateral versus unilateral adrenal neuroblastoma.201727820129
clinical significance of prominent retraction clefts in invasive urothelial carcinoma.micropapillary morphology in invasive urothelial carcinoma is an established predictor of aggressive disease. it is unknown, however, if prominent retraction is associated with more aggressive disease in the absence of classic micropapillary morphology. we reviewed a retrospective series of 309 radical cystectomy specimens with clinical follow-up data and documented the presence or absence of invasive urothelial carcinoma with prominent retraction clefts, defined as invasive carcinoma with retra ...201727818288
does varicocelectomy improve semen analysis outcomes in adolescents without testicular asymmetry?the main indications for adolescent varicocelectomy are testicular hypotrophy or pain. however, we have previously shown that both serial total testicular volume and volume differential are weakly associated with semen quality. the ultimate patient goal is paternity, but semen analysis is critical to appropriate management of varicocele. we hypothesize that varicocelectomy improves total motile count (tmc) among patients who only have abnormal semen analysis (sa) parameters, but not among those ...201727818033
factors which influence treatment initiation for pulmonary non-tuberculous mycobacterium infection in hiv negative patients; a multicentre observational study.clinical, radiological and microbiological criteria inform diagnosis of pulmonary non-tuberculous mycobacteria (ntm) disease and treatment decisions. this multicentre, review aims to characterise ntm disease meeting ats/idsa criteria and define factors associated with initiation of treatment.201627817806
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