| xia-bai-san inhibits lipopolysaccharide-induced activation of intercellular adhesion molecule-1 and nuclear factor-kappa b in human lung cells. | xia-bai-san (xbs) is a traditional chinese medicine that has been used clinically for centuries in asian countries to treat some types of common cold and asthma-like diseases similar to infantile pneumonia and childhood bronchitis. in previous studies, xbs was found to suppress the inflammatory process induced in lungs of mice treated with lipopolysaccharide (lps). | 2009 | 19454309 |
| enhanced flavonoid production in hairy root cultures of glycyrrhiza uralensis fisch by combining the over-expression of chalcone isomerase gene with the elicitation treatment. | economically important compounds, such as licorice flavonoids, are present in insufficient amounts in the hairy roots. to overcome this problem, we took the transgenic approach combined with the elicitation technique to increase the flavonoid production. the glycyrrhiza uralensis fisch cdna encoding chalcone isomerase gene (chi) was over-expressed in hairy roots of g. uralensis fisch mediated by the disarmed agrobacterium rhizogenes a4. stable genetic transformation was confirmed by southern blo ... | 2009 | 19504262 |
| water extract of glycyrrhiza uralensis inhibited enterovirus 71 in a human foreskin fibroblast cell line. | human infection by enterovirus type 71 (ev71) can cause life-threatening meningo-encephalitis. currently, there is no effective anti-ev71 therapy available. since ev71 infection commonly involves skin lesions, we tested our hypothesis that water extract of glycyrrhiza uralensis (g. uralensis) could inhibit the cytopathic effects of ev71 in a human foreskin cell line by using an xtt-based method. our results showed that the water extract of g. uralensis at 3,000 microg/ml has only 30% cytotoxicit ... | 2009 | 19507280 |
| mechanisms of inhibiting proliferation of vascular smooth muscle cells by serum of rats treated with dahuang zhechong pill. | dahuang zhechong pill (dhzcp), a famous and classical chinese herbal prescription, consists of twelve traditional chinese drugs: eupolyphaga sinensis walker., rheum officinale baill., scutellaria baicalensis georgi., glycyrrhiza uralensis fisch., prunus persica batsch., prunus armeniaca l., paeonia lactiflora pall., rehmannia glutinosa libosch., toxicodendron vernicifluum f.a. barkl., tabanus bivittatus mats., hirudo nipponica whitman. and holotrichia diomphalia bates., and is clinically used to ... | 2009 | 19527826 |
| adjuvant activities of saponins from traditional chinese medicinal herbs. | new generation vaccines such as recombinant, antigen purified and dna vaccines are poorly immunogenic due to the lack of an innate immune stimulus. therefore, search of new adjuvants for these vaccines has become a topic of interesting. in new adjuvant development, saponins are outstanding candidates. recently, increased attention has been received on plant-derived saponins in search of new adjuvant candidates from traditional chinese medicinal herbs such as panax ginseng, astragalus species, pa ... | 2009 | 19559122 |
| host legume-exuded antimetabolites optimize the symbiotic rhizosphere. | rhizobia form symbiotic nodules on host legumes and fix nitrogen for their hosts in exchange for nutrients. in order to establish this mutually beneficial relationship, rhizobia must compete with other soil bacteria in the host legume rhizosphere to colonize plant roots efficiently. a promoter-trap transposon screen in mesorhizobium tianshanense, a rhizobium that forms nodules on licorice (glycyrrhiza uralensis) plants revealed that the expression of msia, which encodes a putative exporter prote ... | 2009 | 19602148 |
| ginseng (panax quinquefolius) and licorice (glycyrrhiza uralensis) root extract combinations increase hepatocarcinoma cell (hep-g2) viability. | the combined cytoactive effects of american ginseng (panax quinquefolius) and licorice (glycyrrhiza uralensis) root extracts were investigated in a hepatocarcinoma cell line (hep-g2). an isobolographic analysis was utilized to express the possibility of synergistic, additive or antagonistic interaction between the two extracts. both ginseng and licorice roots are widely utilized in traditional chinese medicine preparations to treat a variety of ailments. however, the effect of the herbs in combi ... | 2009 | 19617200 |
| analysis of fuzhisan and quantitation of baicalin and ginsenoside rb(1) by hplc-dad-elsd. | fuzhisan (fzs) is a traditional chinese medicine composed of radix ginseng rubra (araliaceae family), scutellaria baicalensis georgi (labiatae family), angelica sinensis (oliv) diels (umbelliferae family), anemone altaica fisch. ex c.a. mey (araceae family) and glycyrrhiza uralensis (leguminosae family). to establish the chemical fingerprint of the components of fzs and quantify the components, baicalin and ginsenoside rb(1), a high performance liquid chromatography method coupled with diode arr ... | 2009 | 19641879 |
| mesorhizobium shangrilense sp. nov., isolated from root nodules of caragana species. | five strains of bacteria isolated from nodules of caragana bicolor and caragana erinacea in yunnan province of china were classified within the genus mesorhizobium in the class alphaproteobacteria. the highest degree of 16s rrna gene sequence similarity was determined to be to mesorhizobium loti lmg 6125(t) (99.7 %) and mesorhizobium ciceri upm-ca7(t) (99.7 %). polyphasic taxonomic methods including sds-page of whole-cell soluble proteins, comparative housekeeping sequence analysis of atpd, glni ... | 2009 | 19643905 |
| [culture of transgenic glycyrrhiza uralensis hairy root with licorice squalene synthase (sqs) gene]. | a squalene synthase gene cloned (gusqs1, accession number in genbank database: am182329) from glycyrrhiza uralensis was transferred into g. uralensis via agrobacterium rhizogenes a4 for investigating biosynthesis pathway and enhancing synthesis of glycyrrhizic acid (ga). hypocotyl explants from g. uralensis were infected with a. rhizogenes a4 containing gusqs1 gene to induce the hairy roots. the hairy root lines established were selected in medium containing 0.8 mg x l(-1) phosphinothricin (ppt) ... | 2009 | 19894527 |
| [geographical variation of glycyrrhiza uralensis seed germination character on water stress]. | we studied the licorice provenance rule under the manual simulative water stress conditions, discussed geographical variation pattern and the ecology mechanism and laid the theoretical basis for the licorice seed regionalization and the seed allocation. | 2009 | 20030075 |
| metabolomics study on the anti-depression effect of xiaoyaosan on rat model of chronic unpredictable mild stress. | ethnopharmacology: xiaoyaosan, a famous chinese prescription, composed of poria (poria cocos (schw.) wolf), radix paeoniae alba (paeonia lactiflora pall.), radix glycyrrhizae (glycyrrhiza uralensis fisch.), radix bupleuri (bupleurum chinense dc.), radix angelicae sinensis (angelica sinensis (oliv.) diels), rhizoma atractylodis macrocephalae (atractylodes macrocephala koidz.), herba menthae (mentha haplocalyx briq.), and rhizoma zingiberis recens (zingiber officinale rosc.), has been widely used ... | 2010 | 20079416 |
| isoangustone a present in hexane/ethanol extract of glycyrrhiza uralensis induces apoptosis in du145 human prostate cancer cells via the activation of dr4 and intrinsic apoptosis pathway. | glycyrrhiza uralensis (licorice) is one of the most frequently prescribed ingredients in oriental medicine, and licorice extract has been shown to exert anti-carcinogenic effects. however, its use as a cancer chemopreventive agent is rather limited, due to the fact that its principal component, glycyrrhizin, is known to induce hypertension. this study determined the effects of a hexane/ethanol extract of g. uralensis (hegu), which contains undetectable amounts of glycyrrhizin, on the apoptosis o ... | 2010 | 20229524 |
| [effects of space flight on protein content and electrophoresis in glycyrrhiza uralensis]. | to investigate the space environment on the role of licorice mutagenesis analysis of proteins. | 2010 | 20394277 |
| est analysis reveals putative genes involved in glycyrrhizin biosynthesis. | glycyrrhiza uralensis is one of the most popular medicinal plants in the world and is also widely used in the flavoring of food and tobacco. due to limited genomic and transcriptomic data, the biosynthetic pathway of glycyrrhizin, the major bioactive compound in g. uralensis, is currently unclear. identification of candidate genes involved in the glycyrrhizin biosynthetic pathway will significantly contribute to the understanding of the biosynthetic and medicinal chemistry of this compound. | 2010 | 20423525 |
| inhibition of three selected beverage extracts on alpha-glucosidase and rapid identification of their active compounds using hplc-dad-ms/ms and biochemical detection. | inhibition of alpha-glucosidase is a therapeutic approach for diabetes. in this study, a method based on online liquid chromatography-diode array detection-tandem mass spectrometry and biochemical detection (lc-dad-ms/ms-bcd) was developed to screen and identify alpha-glucosidase inhibitors from selected beverage extracts, including pu-erh tea ( camellia sinensis var. assamica), eagle tea ( litsea coreana levl.), and radix glycyrrhizae ( glycyrrhiza uralensis fisch.). as a result, two components ... | 2010 | 20443596 |
| aldose reductase inhibitory compounds from glycyrrhiza uralensis. | we evaluated the inhibitory effects of components from the root of glycyrrhiza uralensis (g. uralensis) on aldose reductase (ar) and sorbitol formation in rat lenses with high levels of glucose as part of our ongoing search of natural sources for therapeutic and preventive agents for diabetic complications. in order to identify the bioactive components of g. uralensis, 5 prenylated flavonoids (semilicoisoflavone b, 7-o-methylluteone, dehydroglyasperin c, dehydroglyasperin d, and isoangustone a), ... | 2010 | 20460778 |
| hexane-ethanol extract of glycyrrhiza uralensis containing licoricidin inhibits the metastatic capacity of du145 human prostate cancer cells. | licorice extracts are known to exhibit anti-carcinogenic activities. however, chronic licorice consumption can lead to serious side effects due to the presence of considerable quantities of glycyrrhizin, which causes severe hypokalaemia and hypertension. in the present study, we evaluated the effects of a hexane-ethanol extract of glycyrrhiza uralensis (hegu), which lacks glycyrrhizin, on the metastatic characteristics of du145 prostate cancer cells. hegu inhibited basal and epidermal growth fac ... | 2010 | 20487583 |
| [investigation on medicinal plant resources of glycyrrhiza uralensis in china and chemical assessment of its underground part]. | in order to find out the current situation of wild and cultivated resources of glycyrrhiza uralensis, at the same time, the contents of glycyrrhizic acid and liquiritin were detected by hplc. | 2010 | 20617669 |
| glycyrol induces apoptosis in human jurkat t cell lymphocytes via the fas-fasl/caspase-8 pathway. | glycyrrhiza uralensis (leguminosae) has long been used to treat inflammatory ailments, such as gastric ulcers, arthritis, and rheumatism. from this traditional herbal plant, glycyrol, a coumestan with anti-bacterial and anti-inflammatory activities, was first isolated and synthesized to test its apoptosis-inducing properties in human jurkat cells. flow cytometry analysis indicated that glycyrol can arrest the cell cycle in s phase and subsequently induce apoptosis in both time- and dose-dependen ... | 2011 | 20717871 |
| use of yokukansan (tj-54) in the treatment of neurological disorders: a review. | kampo herbal remedies are reported to have a wide range of indications and have attracted attention due to reports suggesting that these remedies are effective when used in disease treatment while maintaining a favourable quality of life. yokukansan, also known as tj-54, is composed of seven herbs; angelica acutiloba, atractylodes lancea, bupleurum falcatum, poria cocos, glycyrrhiza uralensis, cnidium officinale and uncaria rhynchophylla. yokukansan is used to treat insomnia and irritability as ... | 2010 | 20812276 |
| in vitro anti-rotavirus activity of polyphenol compounds isolated from the roots of glycyrrhiza uralensis. | we evaluated the ability of six polyphenols isolated from the roots of glycyrrhiza uralensis to inactivate rotaviruses, specially g5p[7] and g8p[7]. upon finding that all polyphenols possessed anti-rotavirus activity, we evaluated whether these properties were attributable to direct inhibition of the binding of rotavirus to cells and/or to inhibition of viral replication. using the virucidal assay, we found that all six compounds directly inhibited rotavirus binding, with activity being dependen ... | 2010 | 20850329 |
| immunosuppressive activity on the murine immune responses of glycyrol from glycyrrhiza uralensis via inhibition of calcineurin activity. | calcineurin (cn), a unique protein phosphatase, plays an important role in immune regulation. our laboratory has established an effective molecular drug-screening model based on cn activity. | 2010 | 20860439 |
| antimicrobial and antioxidant activities of traditional thai herbal remedies for aphthous ulcers. | four medicinal plants (quercus infectoria, kaempferia galanga, coptis chinensis and glycyrrhiza uralensis) as well as one traditional thai treatment for aphthous ulcers based on these four plants were tested for antimicrobial activity. mic values for a range of bacteria and candida albicans were determined, with both type strains and clinical isolates being used. antioxidant activity was determined using the abts radical scavenging assay. among the four plants, q. infectoria showed antimicrobial ... | 2010 | 20878703 |
| effects on neuroendocrinoimmune network of lizhong pill in the reserpine induced rats with spleen deficiency in traditional chinese medicine. | lizhong pill, composed of radix ginseng (panax ginseng c.a. meyer), rhizoma zingiberis (zingiber officinale roscoe), rhizoma atractylodis macrocephalae (atractylodes macrocephala koidz.) and radix glycytthizae (glycyrrhiza uralensis fisch.), is a classical herbal product for curing spleen deficiency in traditional chinese medicine (tcm), and reserpine treated rats show similar signs to tcm spleen deficiency pattern. this paper is aimed to explore the regulatory effect on neuroendocrinoimmune net ... | 2010 | 20951788 |
| repeated-dose (28 days) oral toxicity study in rats of an antiacne formula (bc-af) derived from plants. | to evaluate the safety of a formula (bc-af) consisting of the extracts of danshen (salvia miltiorrhiza), loquat leaf (glycyrrhiza uralensis), and licorice (eriobotrya japonica), a preliminary 28-day, repeated-dose oral toxicity study was performed in sprague-dawley rats. eighty animals were divided into four groups, with each group comprising 10 male and 10 female rats. bc-af was administered once-daily by oral gavage at doses of 0 (control), 2.5 (low), 5 (middle), and 10 (high) g/kg body weight ... | 2010 | 20954811 |
| anti-inflammatory/anti-oxidative stress activities and differential regulation of nrf2-mediated genes by non-polar fractions of tea chrysanthemum zawadskii and licorice glycyrrhiza uralensis. | accumulating evidence from epidemiological studies indicates that chronic inflammation and oxidative stress play critical roles in neoplastic development. the aim of this study was to investigate the anti-inflammatory, anti-oxidative stress activities, and differential regulation of nrf2-mediated genes by tea chrysanthemum zawadskii (cz) and licorice glycyrrhiza uralensis (le) extracts. the anti-inflammatory and anti-oxidative stress activities of hexane/ethanol extracts of cz and le were invest ... | 2010 | 20967519 |
| [galactomannan from the seeds of ural licorice (glycyrrhiza uralensis fisch.)]. | galactomannans from the seeds of ural licorice (glycyrrhiza uralensis fisch.) obtained by hot water extraction of freshly ripened (ggu-1) and overwintered (ggu-2) seeds were studied. ggu-1 and ggu-2 (yield, 1.98 and 1.99% of the seed weight) had molecular weights of 1379 and 877 kda, respectively; their solutions were characterized by high viscosity ([eta] 1193.1 and 765.8 mg/g, respectively) and optical activity ([alpha]d +64.8 and +65.6 deg, respectively). their galactose-to-mannose ratio was ... | 2010 | 21061605 |
| neuroprotective effect of liquiritin against focal cerebral ischemia/reperfusion in mice via its antioxidant and antiapoptosis properties. | our present study was conducted to investigate whether liquiritin (7-hydroxy-2-[4-[3,4,5-trihydroxy-6-(hydroxymethyl) oxan-2-yl] oxyphenyl]-chroman-4-one, 1), an active component of glycyrrhiza uralensis fisch., exerts a neuroprotective effect against focal cerebral ischemia/reperfusion (i/r) in male institute of cancer research (icr) mice. on the establishment of mice with middle cerebral artery occlusion (mcao) for 2 h and reperfusion for 22 h, liquiritin at the doses of 40, 20, and 10 mg/kg w ... | 2010 | 21128146 |
| design, synthesis and sar study of hydroxychalcone inhibitors of human ß-secretase (bace1). | according to the structural characteristics of isoliquiritigenin from glycyrrhiza uralensis, a series of hydroxychalcones has been designed, synthesized and evaluated for their in vitro inhibitory activities of ß-secretase (bace1). structure-activity relationship study suggested that inhibitory activity against bace1 was governed to a greater extent by the hydroxyl substituent on a- and b-ring of the chalcone, and the most active compound was substituted with four hydroxyl group (17, ic(50)?=?0. ... | 2011 | 21222511 |
| [impacting of polymorphism of beta-amyrin synthase from glycyrrhiza uralensis on its catalytic efficiency]. | to analyze heterologous expression in saccharomyces cerevisiae of two genotypes: beta-as (a-t) genotype which is related to high content of glycyrrhizic acid and beta-as(g-c) genotype which is related to low content of glycyrrhizic acid, and compare two different genotypes on the impact of beta-amyrin production in order to provide a foundation for licorice molecular breeding. | 2010 | 21355256 |
| isoangustone a suppresses mesangial fibrosis and inflammation in human renal mesangial cells. | development of diabetic nephropathy with fibrosis is associated with hypereglycemia-linked inflammation. increased levels of proinflammatory factors have been found in diabetic patients with nephropathy. the present study was to test the hypothesis that isoangustone a, a novel compound present in licorice, can inhibit renal fibrosis and inflammation inflamed by high glucose (hg) in human mesangial cells through disturbing transforming growth factor ß (tgf-ß) and nuclear facor ?b (nf-?b) pathways ... | 2011 | 21367880 |
| cardioprotective effects of glycyrrhiza uralensis extract against doxorubicin-induced toxicity. | the purpose of the present study was to investigate the cardioprotective effects of glycyrrhiza uralensis extract (gue) against doxorubicin (dox)-induced cardiotoxicity. imprinting control region (icr) mice were treated with saline, dox (20 mg/kg intraperitoneal [ip] for once), gue (100 mg/kg intragastric [ig] for 8 days), co-treatments with dox and gue (100 mg/kg ig for 8 days), and amifostine (100 mg/kg intravenous [iv] for once), respectively. serum levels of lactate dehydrogenase (ldh) and c ... | 2011 | 21378374 |
| hexane/ethanol extract of glycyrrhiza uralensis and its active compound isoangustone a induce g1 cycle arrest in du145 human prostate and 4t1 murine mammary cancer cells. | although licorice is known to exert anticarcinogenic effects, it contains large quantities of glycyrrhizin (gl), which causes severe hypertension. we have previously demonstrated that the hexane/ethanol extract of glycyrrhiza uralensis (hegu) contains no detectable gl and suppresses doxorubicin-induced apoptosis in h9c2 rat cardiac myoblasts. the principal objective of this study was to determine whether and by what mechanism hegu and its active component, isoangustone a, inhibit cell-cycle prog ... | 2011 | 21429724 |
| effects of dietary supplementation of chinese medicinal herbs on polymorphonuclear neutrophil immune activity and small intestinal morphology in weanling pigs. | the purpose of this study was to evaluate the effects of dietary chinese medicinal herbs (cmh) supplementation composed of panax ginseng, dioscoreaceae opposite, atractylodes macrocephala, glycyrrhiza uralensis, ziziphus jujube and platycodon grandiflorum, on the performance, intestinal tract morphology and immune activity in weanling pigs. two hundred and forty weaned pigs were assigned randomly to four dietary groups including the negative control (basal diet), 0.1% cmh, 0.3% cmh and 0.114% an ... | 2011 | 21535231 |
| [experimental study on anti-influenza virus infection with yinqiao-decoction by orthogonal design]. | to investigate composition principle of yinqiao-decoction through experiment of anti-influenza. | 2010 | 21604566 |
| protective effects of liquiritin apioside on cigarette smoke-induced lung epithelial cell injury. | cigarette smoking is associated with an increased incidence of chronic obstructive pulmonary disease (copd). in this study, we hypothesized that liquiritin apioside (la), a main flavonoid component from glycyrrhiza uralensis, had antioxidant properties by inducing glutathione (gsh) biosynthesis via the inhibition of cytokines and protected lung epithelial cells against cigarette smoke-mediated oxidative stress. a549 cells were treated with cigarette smoke extract (cse) and/or la. icr mice were e ... | 2011 | 21631586 |
| sinorhizobium fredii hh103 does not strictly require kps and/or eps to nodulate glycyrrhiza uralensis, an indeterminate nodule-forming legume. | the sinorhizobium fredii hh103 rkp-1 region, which is involved in capsular polysaccharide (kps) biosynthesis, is constituted by the rkpu, rkpaghij, and kpsf3 genes. two mutants in this region affecting the rkpa (svq536) and rkpi (svq538) genes were constructed. polyacrylamide gel electrophoresis and (1)h-nmr analyses did not detect kps in these mutants. rt-pcr experiments indicated that, most probably, the rkpaghi genes are cotranscribed. glycine max cultivars (cvs.) williams and peking inoculat ... | 2011 | 21761170 |
| metabonomic study on chronic unpredictable mild stress and intervention effects of xiaoyaosan in rats using gas chromatography coupled with mass spectrometry. | ethnopharmacology: xiaoyaosan (xys), a famous chinese prescription, composed of radix bupleuri (bupleurum chinense dc.), radix angelicae sinensis (angelica sinensis (oliv.) diels), radix paeoniae alba (paeonia lactiflora pall.), rhizoma atractylodis macrocephalae (atractylodes macrocephala koidz.), poria (poria cocos (schw.) wolf), radix glycyrrhizae (glycyrrhiza uralensis fisch.), herba menthae (mentha haplocalyx briq.), and rhizoma zingiberis recens (zingiber officinale rosc.), has been widely ... | 2011 | 21718771 |
| screening of estrogenic and antiestrogenic activities from medicinal plants. | the medicinal plant extracts commercially used in asia were screened for their estrogenic and antiestrogenic activities in a recombinant yeast system featuring both a human estrogen receptor (er) expression plasmid and a reporter plasmid. pueraria lobata (flower) had the highest estrogenic relative potency (rp, 7.75+ù10(-3); rp of 17+¦-estradiol=1), followed by amomum xanthioides (1.25+ù10(-3)). next potent were a group consisting of glycyrrhiza uralensis, zingiber officinale, rheum undulatum, c ... | 2008 | 21783839 |
| Comparative pharmacokinetic studies of peimine and peiminine in rat plasma by LC-MS-MS after oral administration of Fritillaria thunbergii Miq. and Fritillaria thunbergii Miq. - Glycyrrhiza uralensis Fisch. couple extract. | A sensitive LC-MS-MS method has been successfully applied to pharmacokinetic study of peimine and peiminine in rat plasma after oral administration of Fritillaria thunbergii Miq. exact and Fritillaria thunbergii Miq. - Glycyrrhiza uralensis Fisch. couple extract. The results indicated that plasma profiles of peimine and peiminine confirmed to two-compartment open model with weighting function of 1/C2 for data fitting and parameter estimation and the utilization with Glycyrrhiza uralensis Fisch. ... | 2011 | 22026124 |
| Isoflavonoids and Coumarins from Glycyrrhiza uralensis: Antibacterial Activity against Oral Pathogens and Conversion of Isoflavans into Isoflavan-Quinones during Purification. | Phytochemical investigation of a supercritical fluid extract of Glycyrrhiza uralensis has led to the isolation of 20 known isoflavonoids and coumarins, and glycycarpan (7), a new pterocarpan. The presence of two isoflavan-quinones, licoriquinone A (8) and licoriquinone B (9), in a fraction subjected to gel filtration on Sephadex LH-20 is due to suspected metal-catalyzed oxidative degradation of licoricidin (1) and licorisoflavan A (2). The major compounds in the extract, as well as 8, were evalu ... | 2011 | 22074222 |
| anti-angiogenic effects of water extract of a formula consisting of pulsatilla koreana, panax ginseng and glycyrrhiza uralensis. | this study aimed to investigate the anti-angiogenic effects of the water extract of pulsatilla koreana (yabe ex nakai) nakai ex t. mori., panax ginseng c.a. meyer and glycyrrhiza uralensis fisch (weppg). | 2011 | 21906526 |
| estrogenic plant extracts reverse weight gain and fat accumulation without causing mammary gland or uterine proliferation. | long-term estrogen deficiency increases the risk of obesity, diabetes and metabolic syndrome in postmenopausal women. menopausal hormone therapy containing estrogens might prevent these conditions, but its prolonged use increases the risk of breast cancer, as wells as endometrial cancer if used without progestins. animal studies indicate that beneficial effects of estrogens in adipose tissue and adverse effects on mammary gland and uterus are mediated by estrogen receptor alpha (erα). one strate ... | 2011 | 22163294 |
| Biogeography of symbiotic and other endophytic bacteria isolated from medicinal Glycyrrhiza species in China. | A total of 159 endophytic bacteria were isolated from surface-sterilized root nodules of wild perennial Glycyrrhiza legumes growing on 40 sites in central and northwestern China. Amplified fragment length polymorphism (AFLP) genomic fingerprinting and sequencing of partial 16S rRNA genes revealed that the collection mainly consisted of Mesorhizobium, Rhizobium, Sinorhizobium, Agrobacterium and Paenibacillus species. Based on symbiotic properties with the legume hosts Glycyrrhiza uralensis and Gl ... | 2011 | 22066910 |
| [Evaluation of antifungal effects of a traditional medicine containing 17 components on Trichophyton verrucosum and Malassezia pachydermatis by microdilution]. | The minimum inhibitory concentration(MIC)of a traditional medicine containing 17 components against 9 strains of Trichophyton verrucosum and 13 strains of Malassezia pachydermatis was determined using a method recommended by the Clinical and Laboratory Standards Institute(CLSI). We also measured the MIC of each of the 17 components using the same method, and identified the main antifungal components.In order to evaluate MIC as a parameter of the antifungal effects using the microdilution method, ... | 2011 | 21891983 |
| [effects of grazing disturbance on leaf traits and their interrelationships of plants in desert steppe]. | this paper studied the effects of grazing disturbance on the specific leaf area (sla), leaf dry matter content (ldmc), leaf area, and leaf dry mass of dominant plant species cynanchum komarovii, euphorbia esula, glycyrrhiza uralensis, and lespedeza potaninii in desert steppe of ningxia, northwest china, aimed to approach the responses and adaptation strategies of different plant species in desert steppe to the environmental change. with the decrease of grazing intensity, the specific leaf area ( ... | 2012 | 23431780 |
| [analysis on correlation between 3-hydroxy-3-methylglutary-coenzyme a reductase gene polymorphism of glycyrrhiza uralensis and content of glycyrrhizic acid]. | to reveal the 3-hydroxy-3-methylglutary-coenzyme a reductase (hmgr) gene polymorphism of glycyrrhiza uralensis, and the correlation between hmgr gene polymorphism and the content of glycyrrhizic acid. | 2012 | 23627180 |
| [researches on the influence of 3-hydroxy-3-methylglutary-coenzyme a reductase gene polymorphism on catalytic efficiency of its encode enzyme in glycyrrhiza uralensis]. | to analyse the effect of expression proteins containing different escherichia coli of 3-hydroxy-3-methylglutary-coenzyme a reductase(hmgr) genic mutation on the conversion efficiency of mva with gc-ms method, in order to lay a foundation for revealing the function of hmgr gene polymorphism of glycyrrhiza uralensis in the production of high-quality g. uralensis medicines. | 2012 | 23627179 |
| [researches on influence of squalene synthase gene polymorphism on catalytic efficiency of its encode enzyme in glycyrrhiza uralensis]. | to analyse the polymorphism of squalene synthase gene and reveal the influence of squalene synthase (sqs) gene polymorphism on the catalytic efficiency of its encode enzyme in glycyrrhiza uralensi. | 2012 | 23627178 |
| [antidepressant activities of flavonoids from glycyrrhiza uralensis and its neurogenesis protective effect in rats]. | adult rats chronic unpredictable stress model of depression (cus) was adopted to elucidate the antidepressant pharmacological activity and related neurogenesis protective effect of the total flavonoids extract (licorice flavonoids, lf) from the glycyrrhiza uralensis fisch. cultivated locally in ningxia. the rats were exposed to 9 kinds of unpredictable sequence of stressors and were given flavonoids (300 mg x kg(-1), 100 mg x kg(-1) and 30 mg x kg(-1)) for 28 days. the antidepressant effect was ... | 2012 | 23460966 |
| the core structure and immunological activities of glycyrrhizan ua, the main polysaccharide from the root of glycyrrhiza uralensis. | the controlled smith degradation and limited hydrolysis of glycyrrhizan ua, the main phagocytosis-activating polysaccharide isolated from the root of glycyrrhiza uralensis fischer, was performed. the reticuloendothelial system-potentiating, anti-complementary and alkaline phosphatase-inducing activities of glycyrrhizan ua and its degradation products were investigated. methylation analyses of primary, secondary and tertiary smith degradation products and of the limited hydrolysis product indicat ... | 1966 | 1423767 |
| bacterial molecular signals in the sinorhizobium fredii-soybean symbiosis. | sinorhizobium (ensifer) fredii (s. fredii) is a rhizobial species exhibiting a remarkably broad nodulation host-range. thus, s. fredii is able to effectively nodulate dozens of different legumes, including plants forming determinate nodules, such as the important crops soybean and cowpea, and plants forming indeterminate nodules, such as glycyrrhiza uralensis and pigeon-pea. this capacity of adaptation to different symbioses makes the study of the molecular signals produced by s. fredii strains ... | 2016 | 27213334 |
| anti-rotaviral effects of glycyrrhiza uralensis extract in piglets with rotavirus diarrhea. | since rotavirus is one of the leading pathogens that cause severe gastroenteritis and represents a serious threat to human and animal health, researchers have been searching for cheap, safe, and effective anti-rotaviral drugs. there is a widespread of interest in using natural products as antiviral agents, and among them, licorice derived from glycyrrhiza spp. has exerted antiviral properties against several viruses. in this study, anti-rotaviral efficacy of glycyrrhiza uralensis extract (gue) a ... | 2012 | 23244491 |
| tissue-specific and stress-enhancing expression of the tr promoter for mannopine synthase in transgenic medicinal plants. | transgenic tobacco (nicotiana tabacum l.), licorice (glycyrrhiza uralensis fisher) and foxglove (digitalis purpurea l.) were obtained with binary vector systems based on a disarmed agrobacterium tumefaciens and on a virulent a. rhizogenes. the chimeric neomycin phosphotransferase ii (npt-ii) gene (kan) and the ß-glucuronidase (gus) gene (uida) were under the control of the tr1' and 2' promoters, respectively, on a binary vector, pgsgluc1. tissue-specific expression of the chimeric tr2' -uida gen ... | 1991 | 24193927 |
| aspergillus niger enhance bioactive compounds biosynthesis as well as expression of functional genes in adventitious roots of glycyrrhiza uralensis fisch. | in the present study, the culture conditions for the accumulation of glycyrrhiza uralensis adventitious root metabolites in balloon-type bubble bioreactors (btbbs) have been optimized. the results of the culture showed that the best culture conditions were a cone angle of 90° bioreactor and 0.4-0.6-0.4-vvm aeration volume. aspergillus niger can be used as a fungal elicitor to enhance the production of defense compounds in plants. with the addition of a fungal elicitor (derived from aspergillus n ... | 2016 | 26490378 |
| glycyrrhizic acid as the antiviral component of glycyrrhiza uralensis fisch. against coxsackievirus a16 and enterovirus 71 of hand foot and mouth disease. | the radices of glycyrrhiza uralensis fisch. and herbal preparations containing glycyrrhiza spp. have been used for thousands of years as an herbal medicine for the treatment of viral induced cough, viral hepatitis, and viral skin diseases like ulcers in china. glycyrrhizic acid (ga) is considered the principal component in glycyrrhiza spp. with a wide spectrum of antiviral activity. | 2013 | 23454684 |
| structures of new phenolics isolated from licorice, and the effectiveness of licorice phenolics on vancomycin-resistant enterococci. | licorice, which is the underground part of glycyrrhiza species, has been used widely in asian and western countries as a traditional medicine and as a food additive. our continuous investigation on the constituents of roots and stolons of glycyrrhiza uralensis led to the isolation of two new phenolics, in addition to 14 known compounds. structural studies including spectroscopic and simple chemical derivatizations revealed that both of the new compounds had 2-aryl-3-methylbenzofuran structures. ... | 2014 | 25157467 |
| biological synthesis of gold and silver chloride nanoparticles by glycyrrhiza uralensis and in vitro applications. | the current study highlights the rapid biosynthesis of gold nanoparticles (gu-aunps) and silver chloride nanoparticles (gu-agclnps) by aqueous root extract of glycyrrhiza uralensis, a medicinal plant. g. uralensis has been reported for anticancer and hepatoprotective effects. the reduction of chloroauric acid and silver nitrate by the glycyrrhiza root extract prompted the formation of gu-aunps and gu-agclnps within 4 and 40 min at 80 °c, respectively. the complete reaction did not require supple ... | 2017 | 28375686 |
| cloning and characterization of a cdna coding 3-hydroxy-3-methylglutary coa reductase involved in glycyrrhizic acid biosynthesis in glycyrrhiza uralensis. | the roots of glycyrrhiza uralensis are widely used in chinese medicine for their action of clearing heat, detoxicating, relieving cough, dispelling sputum and tonifying spleen and stomach. the reason why glycyrrhiza uralensis has potent and significant actions is that it contains various active secondary metabolites, especially glycyrrhizic acid. in the present study, we cloned the cdna coding 3-hydroxy-3-methylglutary coa reductase (hmgr) involved in glycyrrhizic acid biosynthesis in glycyrrhiz ... | 2013 | 23888704 |
| bioactive constituents of glycyrrhiza uralensis (licorice): discovery of the effective components of a traditional herbal medicine. | traditional herbal medicines have been reported to possess significant bioactivities. in this investigation, a combined strategy using both phytochemical and biological approaches was conducted to discern the effective components of licorice, a widely used herbal medicine. altogether, 122 compounds (1-122), including six new structures (1-6), were isolated and identified from the roots and rhizomes of glycyrrhiza uralensis (licorice). these compounds were then screened using 11 cell- and enzyme- ... | 2016 | 26841168 |
| uralsaponins m-y, antiviral triterpenoid saponins from the roots of glycyrrhiza uralensis. | thirteen new oleanane-type triterpenoid saponins, uralsaponins m-y (1-13), and 15 known analogues (14-28) were isolated from the roots of glycyrrhiza uralensis fisch. the structures of 1-13 were identified on the basis of extensive nmr and ms data analyses. the sugar residues were identified by gas chromatography and ion chromatography coupled with pulsed amperometric detection after hydrolysis. saponins containing a galacturonic acid (1-3) or xylose (5) residue are reported from glycyrrhiza spe ... | 2014 | 24957203 |
| sinorhizobium fredii hh103 rkp-3 genes are required for k-antigen polysaccharide biosynthesis, affect lipopolysaccharide structure and are essential for infection of legumes forming determinate nodules. | the sinorhizobium fredii hh103 rkp-3 region has been isolated and sequenced. based on the similarities between the s. fredii hh103 rkpl, rkpm, rkpn, rkpo, rkpp, and rkpq genes and their corresponding orthologues in helicobacter pylori, we propose a possible pathway for the biosynthesis of the s. fredii hh103 k-antigen polysaccharide (kps) repeating unit. three rkp-3 genes (rkpm, rkpp, and rkpq) involved in the biosynthesis of the hh103 kps repeating unit (a derivative of the pseudaminic acid) ha ... | 2012 | 22397406 |
| anti-hepatitis c virus compounds obtained from glycyrrhiza uralensis and other glycyrrhiza species. | development of complementary and/or alternative drugs for treatment of hepatitis c virus (hcv) infection is still much needed from clinical and economic points of view. antiviral substances obtained from medicinal plants are potentially good targets to study. glycyrrhiza uralensis and g. glabra have been commonly used in both traditional and modern medicine. in this study, extracts of g. uralensis roots and their components were examined for anti-hcv activity using an hcv cell culture system. it ... | 2014 | 24397541 |
| the anti-hsv-1 effect of quercetin is dependent on the suppression of tlr-3 in raw 264.7 cells. | quercetin is a major component of the plant glycyrrhiza uralensis, which is largely used as a traditional medicine in asia. quercetin has been reported to have several biological activities, which include anti-viral and anti-inflammatory effects. we explored the molecular mechanism linking anti-viral and anti-inflammatory activities using an in vitro herpes simplex virus-1 (hsv-1) infection model. raw 264.7 cells were infected with hsv-1 in the presence or absence of different concentrations of ... | 2017 | 28258480 |
| quercetin-induced apoptosis prevents ebv infection. | epstein-barr virus (ebv) is a human gamma-1 herpesvirus that establishes a lifelong latency in over 90% of the world's population. during latency, virus exists predominantly as a chromatin-associated, multicopy episome in the nuclei of a variety of tumor cells derived from b cells, t cells, natural killer (nk) cells, and epithelial cells. licorice is the root of glycyrrhiza uralensis or g. glabra that has traditionally cultivated in eastern part of asia. licorice was reported to have anti-viral, ... | 2015 | 26059439 |
| glycyrrhiza uralensis water extract enhances dendritic cell maturation and antitumor efficacy of hpv dendritic cell-based vaccine. | licorice has been used as herbal medicine and natural sweetener. here, we prepared glycyrrhiza uralensis water extract (guwe) and investigated the effect of guwe on the maturation and function of dendritic cells (dcs) and its adjuvant effect on dc-based vaccine. we observed that guwe dose-dependently promoted dc maturation and cytokine secretion through tlr4 signaling pathway. the capacity of dc to stimulate allogenic splenocyte proliferation was also enhanced by guwe treatment. compared with co ... | 2017 | 28272545 |
| water extract of licorice had anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines. | licorice (glycyrrhiza uralensis fisch., leguminosae) has been used in herbal medicine and food supplement worldwide for centuries. licorice is a common ingredient of several prescriptions of traditional chinese medicine which have been proved to inhibit infection of human respiratory syncytial virus (hrsv). there are two preparations of licorice, radix glycyrrhizae and radix glycyrrhizae preparata. however, it is unknown whether licorice or which preparation of licorice is effective against hrsv ... | 2013 | 23643542 |
| function of msir on canavanine-mediated repression in mesorhizobium tianshanense. | mesorhizobium tianshanense employs msia as canavanine exporter, which is upregulated by msir, to successfully form a symbiosis with the legume glycyrrhiza uralensis. in this research, through gel-shift and bacterial two-hybrid examination, msir was found to spontaneously form dimers and bind to msia promoter without additional canavanine. six truncated forms of msir were constructed, and the conserved helix-turn-helix (hth), substrate-binding, and surface-loop domains were found essential for ms ... | 2015 | 25854984 |
| lsp1, a responsive protein from meyerozyma guilliermondii, elicits defence response and improves glycyrrhizic acid biosynthesis in glycyrrhiza uralensis fisch adventitious roots. | this research explored the effects of protein and polysaccharide in meyerozyma guilliermondii on active compounds in glycyrrhiza uralensis fisch adventitious roots. in this study, a responsive protein lsp1 was purified from the meyerozyma guilliermondii since the excellent induction. the contents of total flavonoids (3.46 mg · g(-1) ), glycyrrhizic acid (0.41 mg · g(-1) ), glycyrrhetinic acid (0.41 mg · g(-1) ), and polysaccharide (94.49 mg · g(-1) ) in adventitious root peaked at lsp1 group, wh ... | 2017 | 28105652 |
| gene expression of glycyrrhizin acid and accumulation of endogenous signaling molecule in glycyrrhiza uralensis fisch adventitious roots after saccharomyces cerevisiae and meyerozyma guilliermondii applications. | this study reports the best culture conditions for roots growth and accumulation of active components by optimizing the parameters. glycyrrhiza uralensis adventitious roots metabolites were significantly increased after adding saccharomyces cerevisiae and meyerozyma guilliermondii. the highest contents of polysaccharide, glycyrrhizic acid, glycyrrhetinic acid and total flavonoids were obtained in meyerozyma guilliermondii group, the content of glycyrrhizic acid was 5.3-fold higher than the contr ... | 2016 | 27644996 |
| ochrobactrum endophyticum sp. nov., isolated from roots of glycyrrhiza uralensis. | a novel gram-staining negative, motile, rod-shaped and aerobic bacterial strain, designated egi 60010(t), was isolated from healthy roots of glycyrrhiza uralensis f. collected from yili county, xinjiang province, north-west china. the 16s rrna gene sequence of strain egi 60010(t) showed 97.2 % sequence similarities with ochrobactrum anthropi atcc 49188(t) and ochrobactrum cytisi esc1(t), and 97.1 % with ochrobactrum lupini lup21(t). the phylogenetic analysis based on 16s rrna gene sequences show ... | 2016 | 26615404 |
| pyrano-isoflavans from glycyrrhiza uralensis with antibacterial activity against streptococcus mutans and porphyromonas gingivalis. | continuing investigation of fractions from a supercritical fluid extract of chinese licorice (glycyrrhiza uralensis) roots has led to the isolation of 12 phenolic compounds, of which seven were described previously from this extract. in addition to these seven metabolites, four known components, 1-methoxyerythrabyssin ii (4), 6,8-diprenylgenistein, gancaonin g (5), and isoglycyrol (6), and one new isoflavan, licorisoflavan c (7), were characterized from this material for the first time. treatmen ... | 2014 | 24479468 |
| reduction of bacterial volatile sulfur compound production by licoricidin and licorisoflavan a from licorice. | halitosis affects a large proportion of the population and is, in most cases, caused by the production of volatile sulfur compounds (vscs), particularly methyl mercaptan and hydrogen sulfide, by specific bacterial species colonizing the oral cavity. in this study, a supercritical extract of chinese licorice (glycyrrhiza uralensis), and its major isoflavans, licoricidin and licorisoflavan a, were investigated for their effect on growth, vsc production and protease activity of porphyromonas gingiv ... | 2012 | 22368239 |
| pseudoclavibacter endophyticus sp. nov., isolated from roots of glycyrrhiza uralensis. | a gram-stain positive, aerobic, rod-shaped, non-motile actinomycete strain, designated egi 60007t, was isolated from healthy roots of glycyrrhiza uralensis f. collected from yili county, xinjiang province, north-west china. a polyphasic approach was applied to study the taxonomic position of the new isolate. the 16s rrna gene sequence of strain egi 60007t had highest sequence similarities with members of the genus pseudoclavibacter: pseudoclavibacter chunganensis cau59t (96.98%), pseudoclavibact ... | 2016 | 26739161 |
| cyp716a179 functions as a triterpene c-28 oxidase in tissue-cultured stolons of glycyrrhiza uralensis. | cyp716a179, a cytochrome p450 monooxygenase expressed predominantly in tissue-cultured stolons of licorice ( glycyrrhiza uralensis ), functions as a triterpene c-28 oxidase in the biosynthesis of oleanolic acid and betulinic acid. cytochrome p450 monooxygenases (p450s) play key roles in the structural diversification of plant triterpenoids. among these, the cyp716a subfamily, which functions mainly as a triterpene c-28 oxidase, is common in plants. licorice (glycyrrhiza uralensis) produces bioac ... | 2017 | 28008473 |
| enhancing the accumulation of beta-amyrin in saccharomyces cerevisiae by co-expression of glycyrrhiza uralensis squalene synthase 1 and beta-amyrin synthase genes. | glycyrrhiza uralensis fisch. ex dc is widely used in traditional chinese medicine (tcm). among its various active components, glycyrrhizic acid is believed to be the marker component. squalene synthase (sqs) and beta-amyrin synthase (beta-as) are key enzymes in the biosynthetic pathway of glycyrrhizic acid in g uralensis. to reveal the effects of co-expression of sqs1 and beta-as genes on this pathway, 7 yeast expression vectors harboring different sqs1 variants and beta-as were constructed and ... | 2014 | 25151748 |
| enhancing production of ergosterol in pichia pastoris gs115 by over-expression of 3-hydroxy-3-methylglutaryl coa reductase from glycyrrhiza uralensis. | the rate-limiting enzyme in the mevalonic acid (mva) pathway which can lead to triterpenoid saponin glycyrrhizic acid (ga) is 3-hydroxy-3-methylglutaryl-coa reductase (hmgr). in order to reveal the effect of copy number variation in the hmgr gene on the mva pathway, the hmgr gene from glycyrrhiza uralensis fisch. (guhmgr) was cloned and over-expressed in pichia pastoris gs115. six recombinant p. pastoris strains containing different copy numbers of the guhmgr gene were obtained and the content o ... | 2014 | 26579379 |
| sinorhizobium fredii hh103 bacteroids are not terminally differentiated and show altered o-antigen in nodules of the inverted repeat-lacking clade legume glycyrrhiza uralensis. | in rhizobial species that nodulate inverted repeat-lacking clade (irlc) legumes, such as the interaction between sinorhizobium meliloti and medicago, bacteroid differentiation is driven by an endoreduplication event that is induced by host nodule-specific cysteine rich (ncr) antimicrobial peptides and requires the participation of the bacterial protein baca. we have studied bacteroid differentiation of sinorhizobium fredii hh103 in three host plants: glycine max, cajanus cajan and the irlc legum ... | 2016 | 26521863 |
| short communication: an in vitro assessment of the antibacterial activity of plant-derived oils. | nonantibiotic treatments for mastitis are needed in organic dairy herds. plant-derived oils may be useful but efficacy and potential mechanisms of action of such oils in mastitis therapy have not been well documented. the objective of the current study was to evaluate the antibacterial activity of the plant-derived oil components of phyto-mast (bovinity health llc, narvon, pa), an herbal intramammary product, against 3 mastitis-causing pathogens: staphylococcus aureus, staphylococcus chromogenes ... | 2014 | 25022682 |
| in vitro antimicrobial activities of 1-methoxyficifolinol, licorisoflavan a, and 6,8-diprenylgenistein against streptococcus mutans. | the objective of the study was to investigate the antimicrobial effects of purified single compounds from ethanol-extracted licorice root on streptococcus mutans. the crude licorice root extract (cle) was obtained from glycyrrhiza uralensis, which was subjected to column chromatography to separate compounds. purified compounds were identified by mass spectrometry and nuclear magnetic resonance. antimicrobial activities of purified compounds from cle were evaluated by determining the minimum inhi ... | 2015 | 25531232 |
| anti‑inflammatory and antioxidant activity of the traditional herbal formula gwakhyangjeonggi‑san via enhancement of heme oxygenase‑1 expression in raw264.7 macrophages. | gwakhyangjeonggi‑san (ghjgs) is a mixture of herbal plants, including agastache rugosa, perilla frutescens, angelica dahurica, areca catechu, poria cocos, magnolia officinalis, atractylodes macrocephala, citrus reticulata, pinellia ternata, platycodon grandiflorum, glycyrrhiza uralensis, ziziphus jujuba and zingiber officinale. ghjgs has been used for treating diarrhea‑predominant irritable bowel syndrome in traditional korean medicine. in the present study, the anti‑inflammatory and antioxidant ... | 2016 | 27052497 |
| molecular screening of chinese medicinal plants for progestogenic and anti-progestogenic activity. | estrogen and progestins have adverse effects, and many of these adverse effects are caused by progestins. due to this, many women choose to use botanical alternatives for hormone replacement therapy, which does not trigger steroidogenic properties. therefore, it is necessary to screen these herbs for progestogenic and anti-progestogenic properties. extract of 13 chinese medicinal plants were analysed for progestogenic and anti-progestogenic activities by using progesterone response element-drive ... | 2014 | 24845509 |
| qualitative and quantitative analysis of amorfrutins, novel antidiabetic dietary natural products, by hplc. | initially isolated from fruits of amorpha fruticosa l. (fabaceae), amorfrutins are promising antidiabetic natural products as selective peroxisome proliferator-activated receptor γ-agonists. | 2016 | 26004584 |
| chinese vegetative materia medica in a venereological treatise by jean astruc from 1740. | historical medical sources can be still queried for forgotten cures and remedies. traditional chinese medicine has dealt with lues venerea (syphilis) since the five dynasties period (10th century). chinese indigenous materia medica and remedies recorded, studied or imported by the europeans can reveal known or quite unknown medicinal plants. the studied jean astruc's work is a published ethnopharmacological survey carried out in beijing in the 1730s and it deserves a modern interpretation. | 2016 | 27132716 |
| [construction and analysis of root cdna library in glycyrrhiza uralensis]. | to screen and isolate secondary metabolite biosynthesis-related gene for establishing the foundation of functional gene research, we construct a cdna library of glycyrrhiza uralensis. | 2008 | 18837336 |
| [relative adscriptions of components in the effective fractions of yinqiao decoction and its composing individual herbs]. | hplc and lc-ms/ms were used to establish a comprehensive hplc analytical method of yinqiao decoction and identify the chemical constituents of the whole and individual herbs of yinqiao decoction. ywg-c18 (250 mm x4. 6 mm id, 10 microm) column was used; the mobile phase was composed of acetonitrile (a) and water ( b, with 3% acetic acid) with gradient elution; the flow rate was 1. 0 ml x min(-1) and the column temperature was set up at 25 degrees c. the detection wavelength was 280 nm. the chroma ... | 2007 | 17518050 |
| changes in microbial diversity, methanogenesis and fermentation characteristics in the rumen in response to medicinal plant extracts. | this study evaluated the in vitro effect of medicinal plant extracts on ruminal methanogenesis, four different groups of methanogens and ruminal fermentation characteristics. a fistulated holstein cow was used as a donor of rumen fluid. licorice and mugwort extracts (glycyrrhiza uralensis and artemisia capillaris, 0.5% and 1% of total substrate dm, respectively), previously used as folk remedies, were added to an in vitro fermentation incubated with buffered-rumen fluid. total gas production in ... | 2013 | 25049911 |
| neuroprotective effect of a novel chinese herbal decoction on cultured neurons and cerebral ischemic rats. | historically, traditional chinese medicine has been widely used to treat stroke. based on the theory of chinese medicine and the modern pharmacological knowledge of herbal medicines, we have designed a neuroprotective formula called post-stroke rehabilitation (psr), comprising seven herbs - astragalus membranaceus (fisch.) bunge, salvia miltiorrhiza bunge, paeonia lactiflora pall., cassia obtusifolia l., ligusticum chuanxiong hort., angelica sinensis (oliv.) diels, and glycyrrhiza uralensis fisc ... | 2016 | 27814708 |
| integrative medicine for relief of nausea and vomiting in the treatment of colorectal cancer using oxaliplatin-based chemotherapy: a systematic review and meta-analysis. | the management of chemotherapy-induced nausea and vomiting (cinv) remains an issue in the treatment of colorectal cancer using oxaliplatin-based regimens. certain traditional plant-based medicines (tms) have histories of use for nausea and vomiting and have been integrated with conventional therapies for cinv. to assess the effectiveness of integrative management of cinv, meta-analysis was conducted of 27 randomised controlled studies (1843 participants) published from 2005 to 2013. the oxalipla ... | 2016 | 26912094 |
| nitric oxide inhibitory flavonoids from traditional chinese medicine formula baoyuan decoction. | three new flavonoid glycosides, (3r)-(+)-isomucronulatol-2'-o-β-d-glucopyranoside (1), (3r)-(-)-isomucronulatol-7-o-β-d-apiofuranosyl(1→2)-β-d-glucopyranoside (2), and (2s)-(-)-7,8-dihydroxylflavanone-4'-o-β-d-apiofuranosyl(1→2)-β-d-glucopyranoside (3), along with eight flavanones (4, 8, 10, 12, 15, 16, 21, and 24), four isoflavones (5, 11, 13, and 23), four chalcones (6, 14, 17, and 18), two isoflavans (19-20), one flavone (7), one flavonol (9), and one dihydrochalcone (22) were isolated from b ... | 2015 | 25889071 |
| synergistic antioxidant activities of eight traditional chinese herb pairs. | many chinese therapeutic herbs that are traditionally used in combination demonstrate significantly better pharmacological effects when used in the combination than when used alone. however, the pharmacological mechanism for this synergism is still not well understood. in the present study, the antioxidant activities of six herbs ((paeonia lactiflora (pl), atractylodes macrocephala (ama), angelica sinensis (as), astragalus membranaceus (ame), glycyrrhiza uralensis (gu) and rheum officinale (ro)) ... | 2009 | 19483308 |
| [the effect of herbal medicine including astragalus membranaceus (fisch) bge, codonpsis pilosula and glycyrrhiza uralensis fisch on airway responsiveness]. | to study the effect of astragalus membranceus(fisch) bge, codonpsis pilosula and glycyrrhiza uralensis fisch on airway responsiveness. | 1998 | 11326953 |
| identification of constituent herbs in ginseng decoctions by dna markers. | dna in herbal decoctions is usually fragmented by extensive boiling and is usually regarded as unsuitable for molecular authentication. this study aims to evaluate the feasibility for molecular authentication methods by multiplex polymerase chain reaction (pcr) and dna sequencing for decoctions. | 2015 | 25657815 |
| dynamic analysis of the endogenous metabolites in depressed patients treated with tcm formula xiaoyaosan using urinary (1)h nmr-based metabolomics. | xiaoyaosan (xys), one of the best-known traditional chinese medicine prescriptions with a long history of use, is composed of bupleurum chinense dc., paeonia lactiflora pall., poria cocos (schw.) wolf, angelica sinensis (oliv.) diels, zingiber officinale rosc., atractylodes macrocephala koidz., glycyrrhiza uralensis fisch., and mentha haplocalyx briq. for centuries, xys has been widely used in china for the treatment of mental disorders such as depression. however, the complicated mechanism unde ... | 2014 | 25448502 |
| lethal hepatocellular necrosis associated with herbal polypharmacy in a patient with chronic hepatitis b infection. | following a short treatment for irritable bowel with the following herbs: astragalus propinquus, codonopsis pilosula, paeonia sp., atractylodes macrocephala, pueraria sp., poria cocos, dioscorea opposita, patriniae, psoralea corylifolia, alpinia katsumadai, glycyrrhiza uralensis and dolomiaea souliei sp. a 43-year-old woman developed acute severe liver failure requiring liver transplantation. histopathological examination of the liver showed massive hepatic necrosis in keeping with drug/chemical ... | 2014 | 24915453 |
| identification of nuclear factor-κb inhibitors and β2 adrenergic receptor agonists in chinese medicinal preparation fuzilizhong pills using uplc with quadrupole time-of-flight ms. | fuzilizhong pills (fzlz), a modified form of a famous traditional chinese medicine (tcm) lizhong wan in treatise on febrile diseases and consisting of panax ginseng c.a.mey. (ren shen), aconitum carmichaelii debx. (fu zi, zhi), glycyrrhiza uralensis fisch., glycyrrhiza inflata bat. or glycyrrhiza glabra l. (gan cao), atractylodes macrocephala koidz. (bai zhu) and zingiber offcinale rosc. (gan jiang), show strong clinical therapeutic effects for dyspnea and pulmonary oedema. however, the bioactiv ... | 2014 | 24115085 |
| the antiinflammatory mechanism of igongsan in mouse peritoneal macrophages via suppression of nf-κb/caspase-1 activation. | igongsan (igs), which is an herbal prescription composed of five different herbs, ginseng radix (root of panax ginseng, araliaceae), atractylodis rhizoma alba (rhizome of atractylodes macrocephala, compositae), poria sclerotium (sclerotium of poria cocos, polyporaceae), glycyrrhizae radix et rhizoma (root and rhizome of glycyrrhiza uralensis, leguminosae), and citri unshius pericarpium (peel of citrus unshiu, rutaceae), has been traditionally used in korea to treat a variety of inflammatory dise ... | 2014 | 23956075 |
| uplc-q-tof-ms/ms fingerprinting of traditional chinese formula sijunzitang. | sijunzitang (sjzt), a classic traditional chinese formula (tcmf) consisting of four herbs, radix ginseng, atractylodes macrocephala, poria cocos and glycyrrhiza uralensis, has been demonstrated to show protective effects on intestine and stomach injure. the chromatographic quality control is needed. uplc-q-tof-ms is a rapid and efficient technique for analysis of complex sample in combination with uplc and tandem mass spectrometry (ms/ms). in this paper, uplc-ms fingerprinting of sjzt was develo ... | 2013 | 23511229 |
| jakyakgamcho-tang and its major component, paeonia lactiflora, exhibit potent anti-glycation properties. | advanced glycation end products (ages) have been implicated in the pathogenesis of diabetes and other age-related diseases. age inhibitors or breakers, such as aminoguanidine and alagebrium, have been proposed as therapeutic agents for age-related disorders. jakyakgamcho-tang (jgt) is a well-known traditional herbal formula, which consists of the radix of paeonia lactiflora pallas (pr) and the radix and rhizome of glycyrrhiza uralensis fisch (gr). the purpose of this study was to evaluate the in ... | 2016 | 28150470 |