Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| identification of dermatophyte species using genomic in situ hybridization (gish). | a genomic in situ hybridization (gish)-based method for dermatophyte identification has been developed. using specific gish probes, discrimination between trichophyton interdigitale, trichophyton rubrum and microsporum canis has been conducted. moreover, gish has been found particularly helpful when proper dermatophyte identification was difficult due to ambiguous pcr-rflp patterns. | 2014 | 24589627 |
| an outbreak of microsporum canis in two elementary schools in a rural area around the capital city of slovenia, 2012. | an outbreak of microsporum canis infection affected 12 persons in two elementary schools over a period of 48 days in 2012 in slovenia. epidemiological, microbiological, and animal investigations were conducted. we defined cases as pupils or employees with skin lesions and confirmed or probable m. canis infection, attending one of the implicated elementary schools. two clusters of six primary and six secondary cases were included in an unmatched case-control study. contact with an adopted stray k ... | 2014 | 24512846 |
| pathogenic fungus microsporum canis activates the nlrp3 inflammasome. | microsporum canis is a pathogenic fungus with worldwide distribution that causes tinea capitis in animals and humans. m. canis also causes invasive infection in immunocompromised patients. to defy pathogenic fungal infection, the host innate immune system is the first line of defense. as an important arm of innate immunity, the inflammasomes are intracellular multiprotein complexes that control the activation of caspase-1, which cleaves proinflammatory cytokine pro-interleukin-1β (il-1β) into it ... | 2014 | 24478101 |
| antifungal potential of essential oil and ethanol extracts of lonicera japonica thunb. against dermatophytes. | the antifungal potential of essential oil and ethanolic leaf extracts of lonicera japonica thunb. was evaluated for controlling the growth of dermatophytes. the oil (1,000 ppm) and extracts (1,500 ppm) of l. japonica revealed 55.1-70.3 % and 40.1-65.5 % antidermatophytic effect against microsporum canis kctc 6348, 6349, 6591, trichophyton rubrum kctc 6345, 6352, 6375, trichophyton mentagrophytes kctc 6077 and 6085, respectively, along with their respective minimum inhibitory concentrations rangi ... | 2014 | 26417269 |
| [in vitro antifungal activity of ravuconazole against isolates of dermatophytes and candida species from patients with dermatomycoses]. | the in vitro activity of ravuconazole (rvcz) was compared with those of itraconazole (itcz) and terbinafine (tbf) against 73 dermatophyte isolates and 18 candida spp. isolates recovered from patients with dermatomycosis at 4 dermatological clinics in japan in 2011. the dermatophyte isolates consisted of trichophyton rubrum (n=51), trichophyton mentagrophytes (n=20 : these strains were not identified by molecular phylogenetic analysis.), trichophyton tonsurans (n=1), and microsporum canis (n=1). ... | 2014 | 25742996 |
| evaluation of trace elements, oxidant/antioxidant status, vitamin c and β-carotene in dogs with dermatophytosis. | the aim of the study was to determine zinc, copper and iron levels, erythrocyte oxidant/antioxidant status, vitamin c and β-carotene in dogs with dermatophytosis. a total of 23 dogs with clinically established diagnosis of dermatophytosis by trichogram and positive fungal culture and six dogs as control were included in this study. on cultural examination 52.17% fungal isolates were found to be microsporum canis, 30.43% were trichophyton mentagrophytes and 17.39% were m. gypseum. in comparison t ... | 2014 | 24329950 |
| identification of dermatophytes by polymerase chain reaction-restriction fragment length polymorphism analysis of metalloproteinase-1. | transgenic research on metalloproteinase-1 is an emerging field in the area of plant molecular biology. the new method reported here can similarly be applied in fungal molecular biology to identify different dermatophytes. our method is more accurate than traditional methods such as molecular analyses. | 2014 | 24966633 |
| multiorgan fungal infection caused by microsporum canis in a green iguana (iguana iguana). | multiple organ invasion by keratinophilic fungi in the green iguana (iguana iguana) has not been previously reported. in this case, a 1-yr-old female green iguana presented with a nodular, darkly discolored skin lesion surrounded by necrosis in the right ventral abdominal region. a cytologic examination of the fine needle aspiration of the lesion revealed an exuberant proliferation of fibroblasts, macrophages, and multinucleated cells along with frequent filamentous structures consistent with hy ... | 2014 | 25000705 |
| tinea capitis caused by microsporum canis infection in a 75-years-old woman. | 2014 | 24990278 | |
| trichophyton species of arthroderma benhamiae - a new infectious agent in dermatology. | in germany, infections due to the zoophilic dermatophyte trichophyton (t.) species of arthroderma benhamiae are being more frequently diagnosed. the source of infection of this emerging pathogen overlaps with that of the zoophilic species t. interdigitale. the most common source are guinea pigs. t. species of arthroderma benhamiae causes inflammatory dermatophytosis in children and adolescents. in addition to tinea capitis, it may cause both tinea corporis, tinea manus and frequently tinea facie ... | 2014 | 24981469 |
| potential effects of trachyspermum copticum essential oil and propolis alcoholic extract on mep3 gene expression of microsporum canis isolates. | the purpose of this study was to evaluate the effects of trachyspermum copticum (t. copticum) essential oil and propolis alcoholic extract on growth and transcription of mep3 gene of microsporum canis (m. canis) strains. | 2014 | 24746722 |
| in vitro activity of the protegrin ib-367 alone and in combination compared with conventional antifungal agents against dermatophytes. | the occurrence of resistance or side effects in patients receiving antifungal agents leads to failure in the treatment of mycosis. the aim of this experimental study was to investigate the in vitro effects of ib-367 alone and in combination with three standard antifungal drugs, fluconazole (flu), itraconazole (itra) and terbinafine (terb), against 20 clinical isolates of dermatophytes belonging to three species. minimum inhibitory concentrations (mics), minimal fungicidal concentrations (mfcs), ... | 2014 | 26058322 |
| comparative study of microsporum canis isolates by dna fingerprinting. | microsporum canis is a zoophilic fungus and it is an important agent of dermatophytosis. cats act as important reservoirs. clinically, it is too difficult to differentiate dermatophytosis caused by various species, also this fungus loses its morphological characteristics easily because of subculture; so using of rapid and accurate laboratory techniques for identifying the dermatophytes is important, therefore, rapd-pcr was applied for the differentiation of the isolates. in this study, 10 m. can ... | 2014 | 24635009 |
| efficacy of disinfectants containing accelerated hydrogen peroxide against conidial arthrospores and isolated infective spores of microsporum canis and trichophyton sp. | accelerated hydrogen peroxide is a proprietary disinfectant formulation that is available for both commercial and home use and is labelled as antifungal. | 2014 | 24617995 |
| rapid detection for rabbit-derived dermatophytes using microsatellite-primed polymerase chain reaction. | a method exhibiting high sensitivity, specificity and rapidity to detect pathogenic dermatophytes was developed using microsatellite-primed polymerase chain reaction (pcr) in combination with a clustering method. the dna fragments of trichophyton mentagrophyton, microsporum gypseum and microsporum canis were amplified by using the primer (gaca)4 to detect the dna polymorphism fingerprints. twenty-one clinical strains identified as t. mentagrophyton, m. gypseum or m. canis by morphological method ... | 2014 | 24296862 |
| susceptibility of clinically important dermatophytes against statins and different statin-antifungal combinations. | the investigation of the antifungal activities of drugs whose primary activities are not related to their antimicrobial potential is in the current forefront of research. statin compounds, which are routinely used as cholesterol-lowering drugs, may also exert direct antimicrobial effects. in this study, the in vitro antifungal activities of various statins (lovastatin, simvastatin, fluvastatin, atorvastatin, rosuvastatin and pravastatin) were examined against one isolate each of four dermatophyt ... | 2014 | 24004389 |
| synthesis, spectral characterization, self-assembly and biological studies of n-acyl-2-pyrazolines bearing long alkoxy side chains. | a series of new pyrazoline derivatives (1b-4c) bearing n-acyl arms and nine to twelve carbon long alkoxy side chains was synthesized and characterized on the basis of spectroscopic data and microanalysis. the nature of self-assembly to understand the interplay of alkoxy chain crystallization and various supramolecular interactions was investigated using single crystal x-ray diffraction studies. interesting self-assembled supramolecular structures of 1b and 4c were observed in the crystal lattice ... | 2014 | 24177882 |
| a study on etiologic agents and clinical manifestations of dermatophytosis in yazd, iran. | dermatophytosis is one of the most common infections of skin, hair, and nails, caused by a group of keratinophilic fungi known as dermatophytes. species identification of these fungi is of great significance from epidemiological and therapeutic points of view. the objective of the present study was to investigate dermatophytosis and its causative agents in patients, referring to the central mycology laboratory of yazd university of medical sciences, yazd, iran. | 2015 | 28681000 |
| fingertip contamination after a brief touch of tinea capitis lesions caused by microsporum canis. | 2015 | 24975367 | |
| management of endemic microsporum canis dermatophytosis in an open admission shelter: a field study. | endemic microsporum canis dermatophytosis was identified in a large, open admission, private, no-kill shelter that admitted >1200 cats per year. fungal culture (fc) screening revealed that 166/210 (79%) and 38/99 (38%) cats in the non-public and public area were culture positive, respectively. however, pending screening fc results, the 99 cats in the public area were treated with once-weekly lime sulfur rinses and monitored with once-weekly fc. cats in the non-public area were not treated. when ... | 2015 | 25074567 |
| phytochemical characterization, antimicrobial activity, and antioxidant potential of equisetum hyemale l. (equisetaceae) extracts. | equisetum hyemale species is considered a medicinal plant used in the form of infusions to combat infectious or inflammation diseases and also diuretic effects, presenting several compounds related to these actions. in previous studies different species of equisetum showed several phenolic compounds. the objective of this study was, for the first time, based on phytochemistry analysis to evaluate the antioxidant and antimicrobial activity. the 70% ethanolic and methanolic extracts of e. hyemale ... | 2015 | 25587637 |
| dermoscopic features in 12 cats with dermatophytosis and in 12 cats with self-induced alopecia due to other causes: an observational descriptive study. | dermoscopy is a noninvasive technique allowing rapid magnified in vivo observation of the skin and structures that lie beneath the skin surface. various congenital and acquired hair shaft abnormalities may also be evaluated by dermoscopy. additionally, characteristic features of microsporum canis-induced tinea capitis and trichotillomania in humans have been reported. | 2015 | 25988302 |
| tinea capitis caused by microsporum canis infection in a 75-year-old woman. | 2015 | 25876151 | |
| digital gene expression analysis of microsporum canis exposed to berberine chloride. | berberine, a natural isoquinoline alkaloid of many medicinal herbs, has an active function against a variety of microbial infections including microsporum canis (m. canis). however, the underlying mechanisms are poorly understood. to study the effect of berberine chloride on m. canis infection, a digital gene expression (dge) tag profiling was constructed and a transcriptome analysis of the m. canis cellular responses upon berberine treatment was performed. illumina/hisseq sequencing technique w ... | 2015 | 25874937 |
| susceptibility of microsporum canis arthrospores to a mixture of chemically defined essential oils: a perspective for environmental decontamination. | the zoophilic dermatophyte microsporum canis has cats as natural reservoir, but it is able to infect a wide range of hosts, including humans, where different clinical features of the so-called ringworm dermatophytosis have been described. human infections are increasingly been reported in mediterranean countries. a reliable control program against m. canis infection in cats should include an antifungal treatment of both the infected animals and their living environment. in this article, a herbal ... | 2015 | 25854840 |
| updating the epidemiology of dermatophyte infections in palestine with special reference to concomitant dermatophytosis. | to determine the epidemiology of dermatophytosis in palestinian patients, detect changes in the etiological agents during the last three decades, and to correlate between concomitant tinea pedis infections, and other cutaneous lesions. | 2015 | 25835157 |
| kennel disinfectants for microsporum canis and trichophyton sp. | the antifungal efficacy of commonly used kennel disinfectants for large surfaces was tested using naturally infective material from untreated animals (m. canis and trichophyton sp.) soaked and macerated but unfiltered leaving visible fluorescing hairs and/or scales in the test inoculum to create a robust challenge. disinfectants included sodium hypochlorite (1 : 32 and 1 : 100), enilconazole (1 : 100), accelerated hydrogen peroxide (1 : 16), potassium peroxymonosulfate (1% and 2%), and calcium h ... | 2015 | 25763290 |
| incidence and etiological agents of genital dermatophytosis in males. | to determine the incidence and etiological agents of dermatophytosis of male genitalia in sarajevo area, bosnia and herzegovina, during a 5-year period (2009-2013). | 2015 | 25669337 |
| in vitro and in vivo antidermatophytic activities of some iranian medicinal plants. | in the last decades, the number of people suffering from dermatophytoses has seriously increased, which may be due to the development of resistant strains to a range of antifungal drugs. the present study was aimed to evaluate the antidermatophytic properties of eight extracts from the selected spices and herbs, which were ethno-medicinally used in iran against trichophyton mentagrophytes, trichophyton interdigitale, microsporum canis, and microsporum gypseum (10 strain of each). the in vitro an ... | 2015 | 26092105 |
| in vitro evaluation of enzymatic and antifungal activities of soil-actinomycetes isolates and their molecular identification by pcr. | human cutaneous infection caused by a homogeneous group of keratinophilic fungi called dermatophytes. these fungi are the most common infectious agents in humans that are free of any population and geographic area. microsporum canis is a cause of dermatophytosis (tinea) in recent years in iran and atypical strain has been isolated in iran. its cases occur sporadically due to m. canis transmission from puppies and cats to humans. since this pathogenic dermatophyte is eukaryotes, chemical treatmen ... | 2015 | 26060560 |
| antifungal activity of berberine hydrochloride and palmatine hydrochloride against microsporum canis -induced dermatitis in rabbits and underlying mechanism. | phellodendron amurense, exhibits antifungal activity mainly by bioactive components including berberine hydrochloride and palmatine hydrochloride. this study was conducted to evaluate the antifungal effects of berberine hydrochloride, palmatine hydrochloride, and a mixture of both substances against microsporum canis in vivo and in vitro. | 2015 | 26054937 |
| [evaluation of the in vitro susceptibility pattern of clinical isolates of trichophyton mentagrophytes and trichophyton rubrum in santiago, chile]. | dermatophytes are a group of keratinophilic fungi able to produce dermatophytosis or tinea infections. in chile, trichophyton rubrum and trichophyton mentagrophytes are the ones most commonly isolated in adults, while microsporum canis is found among children. treatment of these infections is usually with topical or oral antifungals, such as griseofulvin or azole derivatives (clotrimazole, itraconazole, fluconazole), allylamines (terbinafine) or new drugs that are available. | 2015 | 24794211 |
| the anti-dermatophyte activity of allium hirtifolium boiss aqueous extract. | in an attempt at demonstrating the efficacy of allium hirtifolium aqueous extract in control of skin fungal infections as traditional use, we evaluated the anti-dermatophyte activities of a. hirtifolium aqueous extract from bulbs and of ketoconazole against trichophyton rubrum, trichophyton mentagrophytes, microsporum canis, m. gypseum, trichophyton schoenleinii and trichophyton verrucosum var. album by food poisoning technique, disc diffusion and micro broth dilution assays. the anti-fungal act ... | 2015 | 25456419 |
| synthesis and fungistatic activity of aryl aldoxime derivatives. | the antifungal activity of 13 arylaldoxime ester and ether derivatives was tested against 4 dermatophytes trichophyton mentagrophytes (tm), microsporum canis (mc); m. cookei, and m. gypseum. | 2015 | 25499806 |
| newly described features resulting from high-magnification dermoscopy of tinea capitis. | recent studies have reported "comma hairs" as a typical dermoscopic feature of tinea capitis observed at low magnification (×10). the aim of this study was to evaluate the dermoscopic aspects of tinea capitis at high magnification (×150) and its diagnostic role. | 2015 | 25471133 |
| administration of oral itraconazole capsule with whole milk shows enhanced efficacy as supported by scanning electron microscopy in a child with tinea capitis due to microsporum canis. | although diagnosis and treatment of tinea capitis in children are not difficult, treatment failures are still somewhat common. we report a case of pediatric tinea capitis cured using oral itraconazole administered with whole milk, after prior treatment failure when oral itraconazole was administered with water. this apparent enhanced efficacy in one individual was demonstrated using scanning electron microscopy. | 2015 | 26447934 |
| [microsporum canis: current data on the prevalence of the zoophilic dermatophyte in central germany]. | microsporum (m.) canis, whose source of infection is mostly cats, is still considered as the most frequently occurring zoophilic dermatophyte in germany and europe. in distinct areas of germany, the zoophilic dermatophyte trichophyton (t.) anamorph of arthroderma (a.) benhamiae also presents a frequent and emerging causative agent of dermatophytoses. | 2015 | 26446665 |
| evaluation of two molecular techniques for rapid detection of the main dermatophytic agents of tinea capitis. | tinea capitis is very common in western china, with the most widespread aetiological agent being trichophyton violaceum, while microsporum canis is prevalent in the remainder of china. conventional diagnostics and internal transcribed spacer (its) sequencing analyses have proven relatively limited due to the close phylogenetic relationship of anthropophilic dermatophytes. therefore, alternative molecular tools with sufficient specificity, reproducibility and sensitivity are necessary. | 2015 | 26342174 |
| dermatoscopic findings as a complementary tool in the differential diagnosis of the etiological agent of tinea capitis. | tinea capitis is a scalp infection caused by fungi. in brazil, the main causative agents are microsporum canis and the trichophyton tonsurans. etiological diagnosis is based on suggestive clinical findings and confirmation depends on the fungus growth in culture. however, it is not always possible to perform this test due to lack of availability. we reveal the dermoscopic findings that enable distinction between the main causative agents of tinea capitis, m. canis and t. tonsurans. the associati ... | 2015 | 26312662 |
| epidemiological changes in tinea capitis over the sixty years of economic growth in china. | tinea capitis is a fungal infection of the scalp occurring commonly in children. historical data indicate that clinical manifestations and the spectrum of etiologic agents vary greatly with geography, as well as socioeconomic affected populations. | 2015 | 26260745 |
| griseofulvin and fluconazole reduce transmission of tinea capitis in schoolchildren. | we evaluated the efficacy of griseofulvin and fluconazole in reducing the potential for person-to-person transmission of tinea capitis (tc) in children. | 2015 | 26215468 |
| chemical composition and antifungal activity of essential oil from eucalyptus smithii against dermatophytes. | in this study, we evaluated the chemical composition of a commercial sample of essential oil from eucalyptus smithii r.t. baker and its antifungal activity against microsporum canis atcc 32903, microsporum gypseum atcc 14683, trichophyton mentagrophytes atcc 9533, t. mentagrophytes atcc 11480, t. mentagrophytes atcc 11481, and trichophyton rubrum cct 5507. | 2015 | 26676500 |
| tinea faciei caused by trichophyton mentagrophytes in a 20-day-old neonate. | although candidiasis in newborns is not uncommon, superficial dermatophyte infections of infants is quite rare. the causative agents of neonatal tinea reported in various case studies have been trichophyton rubrum, microsporum canis, microsporum gypseum, and trichophyton violaceum. to the best of our knowledge, no case report of neonatal tinea faciei caused by trichophyton mentagrophytes has been reported earlier. | 2015 | 26904450 |
| antifungal activity of cymbopogon nardus (l.) rendle (citronella) against microsporum canis from animals and home environment. | dermatophytosis is a common zoonosis in urban centers. dogs and cats have played an important role as its disseminators. environmental decontamination is essential for the prevention of its propagation to humans and animals. however, sanitizers or disinfectants with antifungal activity, currently available, have high toxicity. the present study evaluated the in vitro effects of an extract of citronella (cymbopogon nardus) on 31 microsporum canis isolates from animals and home environments. susce ... | 2015 | 27049705 |
| detection and characterization of zoonotic dermatophytes from dogs and cats in and around kolkata. | the ringworms of pet dogs, cats, and stray animals (dogs, cats, and other animals) could be a potential source of zoonotic infections causing a serious public health problem in the busy city kolkata. the pet owners are more susceptible to get this infection from their pets, because of the close contact with them as dermatophytosis is very much prevalent in those pets. so, this study was aimed to check the prevalence of dermatophytosis in dogs, cats, and in pet owners. | 2015 | 27047202 |
| [a recurrent case of adult favus successfully treated with terbinafine]. | favus or tinea capitis favosa, is a chronic inflammatory dermatophytosis of the scalp. the disease is particularly common in children aged 6 to 10 years, more often in boys, and it also occurs in adults. human-to-human transmission is therefore possible. anthropophilic trichophyton schöenleinii is responsible for over 95% of favus cases. in addition, there are rare cases of anthropophilic t.violaceum, zoophilic (t.verrucosum, t.quinckeanum, and microsporum canis) and geophilic m.gypseum species ... | 2015 | 26649420 |
| tinea corporis, caused by microsporum canis - a case report from kosovo. | tinea corporis (b35.6) caused by microsporum canis which is fungal species that causes numerous forms of disease. it is part of a group of fungi known as dermatophytes. though mostly well known for ringworm in pets, it is also known to infect humans. this fact makes this pathogen both anthrophilic and zoophilic in nature. microsporum canis is a communicable pathogen. | 2015 | 26622092 |
| essential oil of algerian eucalyptus citriodora: chemical composition, antifungal activity. | essential oil of eucalyptus citriodora is a natural product which has been attributed for various medicinal uses. in the present investigation, e. citriodora essential oil was used to evaluate its antifungal effect against medically important dermatophytes. | 2015 | 26597375 |
| assessment of immunogenicity and protective efficacy of microsporum canis secreted components coupled to monophosphoryl lipid-a adjuvant in a vaccine study using guinea pigs. | microsporum canis is the most common dermatophyte in pets and is of zoonotic importance but currently there is no effective vaccine available to prevent dermatophytosis. the aim of this work was to assess the immunogenicity and protective efficacy of secreted components (sc) from m. canis adjuvanted with the monophosphoryl lipid-a (mpla), in a vaccine study using the guinea pig as an experimental model. animals were vaccinated with either the sc adjuvanted with the mpla, the mpla adjuvant alone ... | 2015 | 25532779 |
| in vitro activity of twenty commercially available, plant-derived essential oils against selected dermatophyte species. | the in vitro activity of twenty chemically defined essential oils (eos) obtained from boswellia sacra, citrus bergamia, c. limon, c. medica, cinnamomum zeylanicum, eucalyptus globulus, foeniculum vulgare, helichrysum italicum, illicium verum, litsea cubeba, mentha spicata, myrtus communis, ocimum basilicum, origanum majorana, o. vulgare, pelargonium graveolens, rosmarinus officinalis, santalum album, satureja montana, and thymus serpyllum was assayed against clinical animal isolates of microspor ... | 2015 | 26434145 |
| anti-dermatophyte efficacy and environmental safety of some essential oils commercial and in vitro extracted pure and combined against four keratinophilic pathogenic fungi. | establish new biocontrol practices with low persistence in the environment against dermatophyte causing mycosis. | 2015 | 25953414 |
| [2011 epidemiological survey of dermatomycoses in japan]. | an epidemiological survey of dermatomycoses and their causative fungus flora in japan for 2011 was conducted in accordance with methods and criteria of the past four surveys. the survey covered a total number of 36,052 outpatients who visited 12 dermatological clinics throughout japan. the results were as follows. 1）dermatophytosis was the most prevalent cutaneous fungal infection (2,980 cases) seen in these clinics, followed by candidiasis (378 cases) and then malassezia infections (152 cases). ... | 2015 | 26617109 |
| dermatophytosis: a 16-year retrospective study in a metropolitan area in southern brazil. | dermatophytoses are considered a public health problem. the objectives of this study were to determine the evolution of their prevalence in the metropolitan area of porto alegre, brazil, and to analyze the dermatophyte species distribution according to body site and demographic characteristics of the patients. | 2015 | 26322879 |
| use of restriction fragment length polymorphism to rapidly identify dermatophyte species related to dermatophytosis. | dermatophytes are a group of keratinophilic fungi worldwide, which can infect the skin, hair and nails of humans and animals. this genus includes several species that present different features of dermatophytosis. although, laboratory diagnosis of dermatophytes is based on direct microscopy, biochemical tests and culture, these manners are expensive, time consuming and need skilled staff. therefore, molecular methods like pcr-rflp are the beneficial tools for identification, which are rapid and ... | 2015 | 26301058 |
| inhibitory effect of silver nanoparticles mediated by atmospheric pressure air cold plasma jet against dermatophyte fungi. | in an in vitro study with five clinical isolates of dermatophytes, the mic(50) and mic(100) values of silver nanoparticles (agnps) ranged from 5 to 16 and from 15 to 32 μg ml(- 1), respectively. the combined treatment of agnps with atmospheric pressure-air cold plasma (apacp) induced a drop in the mic(50) and mic100 values of agnps reaching 3-11 and 12-23 μg ml(- 1), respectively, according to the examined species. epidermophyton floccosum was the most sensitive fungus to agnps, while trichophyt ... | 2015 | 26296782 |
| a multi-target approach toward the development of novel candidates for antidermatophytic activity: ultrastructural evidence on α-bisabolol-treated microsporum gypseum. | multi-target strategies are directed toward targets that are unrelated (or distantly related) and can create opportunities to address different pathologies. the antidermatophytic activities of nine natural skin lighteners: α-bisabolol, kojic acid, β-arbutin, azelaic acid, hydroquinone, nicotinamide, glycine, glutathione and ascorbyl tetraisopalmitate, were evaluated, in comparison with the known antifungal drug fluconazole, on nine dermatophytes responsible for the most common dermatomycoses: mi ... | 2015 | 26132903 |
| antidermatophytic activity of mikania micrantha kunth: an invasive weed. | the incidence of dermatophytosis has risen dramatically in recent years. limited availability of side-effect free drugs has led to a search for new antidermatophytic agents. | 2015 | 26109783 |
| antimicrobial and antioxidant activities and chemical characterization of essential oils of thymusvulgaris, rosmarinus officinalis, and origanum majorana from northeastern méxico. | there have been no reports of antifungal activity and composition of extracts from thymus vulgaris, rosmarinus officinalis or origanum majorana from northeastern méxico. antifungal activity of these oils against trichophyton rubrum, trichophyton tonsurans, trichophyton mentagrophytes, microsporum gypseum, microsporum canis and epidermophyton floccosum was measured by diffusion assay. additionally, antibacterial and antioxidant activities were evaluated. antibacterial activity against staphylococ ... | 2015 | 25631514 |
| therapeutic switching: from antidermatophytic essential oils to new leishmanicidal products. | this study examined whether the antidermatophytic activity of essential oils (eos) can be used as an indicator for the discovery of active natural products against leishmania amazonensis. the aerial parts of seven plants were hydrodistilled. using broth microdilution techniques, the obtained eos were tested against three strains of dermatophytes (trichophyton mentagrophytes, microsporum gypseum and microsporum canis). to compare the eos antifungal and antiparasitic effects, the eos activities ag ... | 2015 | 25742270 |
| therapeutic switching: from antidermatophytic essential oils to new leishmanicidal products. | this study examined whether the antidermatophytic activity of essential oils (eos) can be used as an indicator for the discovery of active natural products against leishmania amazonensis. the aerial parts of seven plants were hydrodistilled. using broth microdilution techniques, the obtained eos were tested against three strains of dermatophytes (trichophyton mentagrophytes, microsporum gypseum and microsporum canis). to compare the eos antifungal and antiparasitic effects, the eos activities ag ... | 2015 | 25714080 |
| dermatophyte and non dermatophyte fungi in riyadh city, saudi arabia. | dermatophytes are a scientific label for a group of three genera (microsporum, epidermophyton and trichophyton) of fungus that causes skin disease in animals and humans. conventional methods for identification of these fungi are rapid and simple but are not accurate comparing to molecular methods. | 2015 | 26288566 |
| myrtus communis l. as source of a bioactive and safe essential oil. | in algeria, myrtus communis l. is distributed throughout the tell atlas and the coastal regions of algiers and constantine. the leaves are used in respiratory disorders, diarrhea and hemorrhoids. the aims of this work were to evaluate the antifungal and anti-inflammatory potential of well characterized essential oils (eo). since eo can be applied by inhalation, dermal application and oral administration, we used several mammalian cell lines to assess safe bioactive doses. the chemical compositio ... | 2015 | 25446467 |
| in vitro antifungal activity of some traditional persian medicinal plants on pathogenic fungi. | to investigate the antifungal activities of the extracts and sub-fractions of phlomis olivieri, verbascum speciosum, sambucus ebulus and erigeron hyrcanicus, four persian medicinal plants used in iranian folk medicine. | 2015 | 26129901 |
| hemolytic activity of dermatophytes species isolated from clinical specimens. | hemolytic activity was recently reported for several pathogenic fungal species, such as aspergillus, candida, trichophyton, penicillium and fusarium. based on a number of mechanistic and characterization studies, several fungal hemolysins have been proposed as virulence factors. hemolysins lyse red blood cells resulting in the release of iron, an important growth factor for microbes especially during infection. the requirement of iron in fungal growth is necessary for metabolic processes and as ... | 2015 | 25467819 |
| solid lipid nanoparticles containing copaiba oil and allantoin: development and role of nanoencapsulation on the antifungal activity. | the aim of this work was to develop solid lipid nanoparticles (sln) containing copaiba oil with and without allantoin (ncoa, nco, respectively) and to evaluate their antifungal activity. nanoparticle suspensions were prepared using a high homogenisation technique and characterised by dynamic light scattering, laser diffraction, nanoparticle tracking analysis, multiple light scattering analysis, high-pressure liquid chromatography, ph and rheology. the antifungal activities of the formulations we ... | 2015 | 25980176 |
| antiproliferative effect and characterization of a novel antifungal peptide derived from human chromogranin a. | cga-n46 is a novel antifungal peptide derived from the n-terminus of human chromogranin a, corresponding to the 31st to 76th amino acids. further research on its activities and characteristics may be helpful for the application of cga-n46 in medical or other situations. in the present study, the antifungal spectrum and physicochemical characteristics of cga-n46 were investigated using an antifungal assay, its antiproliferative effects on cancer and normal cells were assessed using mtt assay and ... | 2015 | 26668630 |
| report: antibacterial and antifungal activities of leaf extract of achyranthes aspera (amaranthaceae) from pakistan. | alcoholic extract and various fractions of achyranthes aspera leaves, traditionally used in pakistan for treatment of infectious diseases was screened for in vitro antibacterial and antifungal activity. the chloroform and butanol fractions were found to be the most active among the fractions, showing considerable antibacterial activity against shigella flexneri and escherichia coli. the highest activity was found in the ethylacetate fraction (17 mm zone of inhibition) against gram-negative (salm ... | 2015 | 26408900 |
| design, synthesis and in vitro bactericidal/fungicidal screening of some vanadyl(iv)complexes with mono- and di-substituted ons donor triazoles. | a new series of anti-bacterial and anti-fungal mono- and di-substituted triazoles (l(1))-(l(6)) have been synthesized and characterized on the basis of their physical, spectral and analytical data. the ligands (l(1))-(l(6)) on reaction with vanadyl(iv) sulphate led to the formation of vanadyl(iv) metal complexes (1)-(4). the structure of the complexes has been established on the basis of their physical, spectral and elemental analyses data. the synthesized ligands and their vanadyl(iv) complexes ... | 2015 | 25716124 |
| molecular identification of fungal pathogens in nodular skin lesions of cats. | in a retrospective study, we investigated 52 formalin-fixed, paraffin-embedded (ffpe) samples from cats with histologically confirmed cutaneous and subcutaneous mycoses to determine if the pathogens could be identified by molecular methods. aim of the study was to obtain a deep understanding of the spectrum of infectious agents, which, as we hypothesized, was not available by histopathology alone. detection of feline and fungal dna was achieved in 92.3% and 94.2% of the samples, respectively. mo ... | 2015 | 25550386 |
| biologically active and thermally stable polymeric schiff base and its metal polychelates: their synthesis and spectral aspects. | new metal polychelates of mn(ii), co(ii), ni(ii), cu(ii) and zn(ii) obtained by the interaction of metal acetates with polymeric schiff base containing formaldehyde and piperazine, have been investigated. structural and spectroscopic properties have been evaluated by elemental analysis, ft-ir and (1)h-nmr. geometry of the chelated polymers was confirmed by magnetic susceptibility measurements, uv-visible spectroscopy and electron spin resonance. the molecular weight of the polymer was determined ... | 2015 | 25955762 |
| a survey of the etiological agents of scalp and nail dermatophytosis in yazd, iran in 2014-2015. | tinea capitis and tinea unguium are regarded as global public health concerns. the purpose of the present study was to identify the etiological agents of tinea capitis and tinea unguium in patients, referring to the central laboratory of yazd university of medical sciences, yazd, iran. | 2015 | 28680997 |
| evaluation of antifungal effect of silver nanoparticles againstmicrosporum canis,trichophyton mentagrophytesandmicrosporum gypseum. | dermatophytosis is the common cutaneous infections in humans and animals, which is caused by the keratinophylic fungus called dermatophytes. in recent years, drugs resistance in pathogenic fungi, including dermatophyte strains to the current antifungals have been increased. | 2015 | 28959308 |
| composition and antifungal activity of zhumeria majdae essential oil. | essential oils extracted from different plants are extensively used in perfume, beverage, and food industries and are reported to exhibit antimicrobial activities against a variety of fungi. zhumeria majdae belonging to the lamiaceae family is a rare and endemic medicinal plant species in iran, with a strong and pleasant odor. the leaves of this plant have been used for many years as an antiseptic carminative agent for the treatment of stomachache (especially in infants) and dysmenorrhea. | 2015 | 28680999 |
| antifungal and antioxidant activities of organic and aqueous extracts of annona squamosa linn. leaves. | an increasing demand for natural additives has shifted the attention from synthetic to natural antioxidants and antifungal agents. this study was carried out to evaluate the antifungal and antioxidant activities of methanol, chloroform, and aqueous extracts of annona squamosa linn. leaves. the antifungal activities of all extracts of a. squamosa leaves against five different strains of fungi (alternaria alternata, candida albicans, fusarium solani, microsporum canis, and aspergillus niger) were ... | 2015 | 28911497 |
| proteolytic activity and cooperative hemolytic effect of dermatophytes with different species of bacteria. | globally, dermatophytes are the most common filamentous group of fungi causing cutaneous mycoses. dermatophytes were shown to secrete a multitude of enzymes that play a role in their pathogenesis. there is limited data on co-hemolytic (camp-like) effect of different bacterial species on dermatophyte species. in this study, we sought to the evaluate exoenzyme activity and co-hemolytic effect of four bacteria on clinical dermatophytes isolated from patients in shiraz, iran. | 2016 | 28959790 |
| phytochemical analysis, antibacterial, and antifungal assessment of aerial parts of polygonatum verticillatum. | the current study was designed to assess the phytochemical profile, antibacterial, and antifungal activities of the crude methanol extract of the aerial parts of polygonatum verticillatum (pa) and its various subsequent solvent fractions using agar well diffusion, agar tube dilution, and microdilution methods. phytochemical analysis showed positive for different chemical groups and also contained marked quantity of saponin and flavonoid contents. significant antibacterial activity was observed a ... | 2016 | 24311628 |
| antimicrobial activity of new 2-thioxo-benzo[g]quinazolin-4(3h)-one derivatives. | the antimicrobial activity of a synthesized series of 28 2-thioxo-benzo[g]quinazolin-4(3h)-one derivatives was evaluated in vitro against five gram-positive bacteria, including bacillus subtilis, enterococcus faecalis, staphylococcus aureus, staphylococcus epidermidis and streptococcus pyogenes. the antibacterial activity was extended to include five gram-negative bacteria: pseudomonas aeruginosa, escherichia coli, proteus mirabilis, klebsiella oxytoca and enterobacter cloacae. furthermore, the ... | 2016 | 27306606 |
| antimicrobial activity of synthesized 2-methylthiobenzo[g][1,2,4]- triazolo[1,5-a]quinazoline derivatives. | the present study was carried out to evaluate the antimicrobial activity of a synthesized 2-methylthio-benzo[g][1,2,4]triazolo[1,5- a]quinazoline series. the compounds (1-21) were tested against a variety of gram-positive bacterial species including bacillus subtilis (rcmb 01001 69-3), enterococcus faecalis (rcmb 0100154-2), staphylococcus aureus (rcmb 0100183-9), staphylococcus epidermidis (rcmb 0100183-9) and streptococcus pyogenes (rcmb 0100172-5). in addition, gram-negative bacteria were als ... | 2016 | 27140181 |
| metal-based ethanolamine-derived compounds: a note on their synthesis, characterization and bioactivity. | metal-based ethanolamines, (l(1))-(l(4)) coordinated with co(ii), cu(ii), ni(ii) and zn(ii) metals in 1:2 (metal:ligand) molar ratio to produce new compounds have been reported. these compounds were screened for their bactericidal/fungicidal activity against a number of bacterial (escherichia coli, shigella flexneri, pseudomonas aeruginosa, salmonella typhi, staphylococcus aureus and bacillus subtilis) and fungal strains (trichophyton longifusus, candida albicans, aspergillus flavus, microsporum ... | 2016 | 27557038 |
| in vitro antimicrobial activities of animal-used quinoxaline 1,4-di-n-oxides against mycobacteria, mycoplasma and fungi. | the quinoxaline 1,4-di-n-oxides (qdnos) were known as potent antibacterial agents. for the purpose of evaluating the bioactivity of existing animal-used qdnos drugs against representative pathogenic microorganism, the representative drugs of quinoxalines including cyadox, mequindox, quinocetone and their metabolites were submitted to the in vitro evaluation for antituberculosis, antimycoplasma, antifungal and antiviral activities. | 2016 | 27600955 |
| [superficial mycoses: casuistry of the mycology department of the instituto nacional de higiene "rafael rangel", caracas, venezuela (2001-2014)]. | the superficial mycoses are very common infectious diseases and therefore are a frequent reason for medical consultation. the aim of this study was to determine the diagnostic frequency of superficial mycoses in the mycology department of the instituto nacional de higiene "rafael rangel" during 14 years (2001-2014). a retrospective cross-sectional study was performed to review the mycological records of patients with presumptive diagnosis of superficial mycosis. nails, hairs and epidermal scales ... | 2016 | 27382801 |
| antifungal, antiradical and cytotoxic activities of extractives obtained from tagetes patula l. (asteraceae), a potential acaricide plant species. | tagetes patula l. shows a complex chemical composition, ranging from glycosylated flavonoids and thiophenes in extracts until terpenoids in the essential oil. in the present study, due to this rich flavonoidic constitution, its antioxidant potential was determined, having shown values of antiradical percentage superior to reference compounds, mainly the extracts prepared with flowers. previous studies performed emphasized the acaricide potential of t. patula and thus, the present study aimed to ... | 2016 | 26945559 |
| antifungal properties of hypericin, hypericin tetrasulphonic acid and fagopyrin on pathogenic fungi and spoilage yeasts. | the role of hypericin-mediated photodynamic antimicrobial properties on pathogenic fungi and photodynamic therapy for human cancer cells is known. antifungal properties of hypericum perforatum l. (hypericaceae) and fagopyrum esculentum moench. (polygonaceae) extracts were also studied. the different polarities of solvents can cause complication in the identification of antifungal effects of separate biologically active compounds. in recent experimental work, we compared antifungal properties of ... | 2016 | 27564138 |
| epidemiology of superficial mycoses in northern greece: a 4-year study. | superficial mycoses are defined as the fungal infections of skin, hair or nails that are caused by dermatophytes, yeasts and non-dermatophytic moulds. dermatophytes are the most frequently isolated fungi from specimens of patients with superficial mycoses. | 2016 | 25851424 |
| lenghty reverse poly(butylene oxide)-poly(ethylene oxide)-poly(butylene oxide) polymeric micelles and gels for sustained release of antifungal drugs. | in this work, we present a detailed study of the potential application of polymeric micelles and gels of four different reverse triblock poly(butylene oxide)-poly(ethylene oxide)-poly(butylene oxide) copolymers (boneombon, where n denotes the respective block lengths), specifically bo8eo90bo8, bo14eo378bo14, bo20eo411bo20 and bo21eo385bo21, as effective drug transport nanocarriers. in particular, we tested the use of this kind of polymeric nanostructures as reservoirs for the sustained delivery ... | 2016 | 27289012 |
| an epidemiological study of animals dermatomycoses in iran. | to determine the fungal species isolated from skin lesions of different animals suspected of having dermatomycoses and their prevalence in different regions of iran. | 2016 | 27180290 |
| synthesis and evaluation of thiophene-based guanylhydrazones (iminoguanidines) efficient against panel of voriconazole-resistant fungal isolates. | a series of new thiophene-based guanylhydrazones (iminoguanidines) were synthesized in high yields using a straightforward two-step procedure. the antifungal activity of compounds was evaluated against a wide range of medicaly important fungal strains including yeasts, molds, and dermatophytes in comparison to clinically used drug voriconazole. cytotoxic properties of compounds were also determined using human lung fibroblast cell line and hemolysis assay. all guanylhydrazones showed significant ... | 2016 | 26867487 |
| efficacy of topical therapy with newly developed terbinafine and econazole formulations in the treatment of dermatophytosis in cats. | in the field of veterinary dermatology dermatophytosis is one of the most frequently occurring infectious diseases, therefore its treatment should be effective, convenient, safe and inexpensive. the aim of this study was to evaluate the efficacy of newly developed topical formulations in the treatment of cats with dermatophytosis. evaluation of clinical efficacy and safety of terbinafine and econazole formulations administered topically twice a day was performed in 40 cats. cats, suffering from ... | 2016 | 27760032 |
| isolation and identification of microsporum canis from asian elephants (elephas maximus) in the chongqing zoo, china. | skin diseases affect millions of people and animals worldwide, including asian elephants. this study sought to determine the pathogen of skin diseases that occurred in asian elephants in chongqing zoo, china. the isolated fungus was identified through its cultural characteristics, morphology, and polymerase chain reaction (pcr) amplification. the pcr amplification using common fungal primers (its1 and its4) determined that the pathogen was 99.7% homologous to microsporum canis. this is the first ... | 2016 | 27691957 |
| molecular characterization and in vitro antifungal susceptibility of 316 clinical isolates of dermatophytes in iran. | dermatophytosis is a common mycotic infection of the skin, nail, and hair, associated with major public health concern worldwide. various species of dermatophytes show significant differences in susceptibility to antifungals. here, we present the antifungal susceptibility of a large collection of molecularly identified dermatophyte isolates obtained from tropical region of south of iran. a total of 9485 patients clinically suspected to have cutaneous fungal infections were examined. dermatophyto ... | 2016 | 26369643 |
| isolation, identification, and in vitro antifungal susceptibility testing of dermatophytes from clinical samples at sohag university hospital in egypt. | the objective of this study was to isolate, identify, and explore the in-vitro antifungal susceptibility pattern of dermatophytes isolated from clinically suspected cases of dermatophytosis (tinea infections) attending the dermatology outpatient clinic. | 2016 | 27504173 |
| species identification of dermatophytes in paraffin-embedded biopsies with a new polymerase chain reaction assay targeting the internal transcribed spacer 2 region and comparison with histopathological features. | dermatophytosis is a very common skin infection with a broad clinical spectrum. biopsies are often used to confirm the diagnosis, especially when the clinical presentation is unusual. not uncommonly, organisms are hard to find even with periodic acid-schiff stains. polymerase chain reaction (pcr) for dermatophytes can be used in such cases. | 2016 | 26556042 |
| detection of common dermatophytes in clinical specimens using a simple quantitative real-time taqman polymerase chain reaction assay. | dermatophytes are common fungal pathogens causing mostly superficial infections in humans with a high prevalence worldwide. traditional detection techniques are time-consuming and insensitive, whereas molecular detection methods have proved to be much more rapid and sensitive. | 2016 | 26406273 |
| epidemiology of dermatophytoses in crete, greece. | dermatophytoses are among the most frequently diagnosed skin infections worldwide. however, the distribution of pathogenic species and the predominating anatomical sites of infection vary with geographical location and change over time. the aim of this study was to determine the epidemiological and aetiological factors of dermatophytoses in crete, greece over the last 5-year period (2011-2015) and their incidence in relation to the gender and the age of the patients. we compared our findings wit ... | 2016 | 27904054 |
| computational analysis of conserved coil functional residues in the mitochondrial genomic sequences of dermatophytes. | dermatophyte is a group of closely related fungi that have the capacity to invade keratinized tissue of humans and other animals. the infection known as dermatophytosis, caused by members of the genera microsporum, trichophyton, and epidermophyton includes infection to the groin (tinea cruris), beard (tinea barbae), scalp (tinea capitis), feet (tinea pedis), glabrous skin (tinea corporis), nail (tinea unguium), and hand (tinea manuum). the identification of evolutionary relationship between thes ... | 2016 | 28149055 |
| antidermatophytic action of resorcinol derivatives: ultrastructural evidence of the activity of phenylethyl resorcinol against microsporum gypseum. | in this work, we evaluated the antidermatophytic activities of three resorcinol derivatives that have a history of use in dermo-cosmetic applications to discover molecules with multiple dermatological activities (i.e., multi-target drugs), thereby reducing the cost and time necessary for new drug development. the antidermatophytic activities of the three skin lighteners were evaluated relative to the known antifungal drug fluconazole on nine dermatophytes responsible for the most common dermatom ... | 2016 | 27706019 |
| characterization of clinically important dermatophytes in north of iran using pcr-rflp on its region. | dermatophytosis is considered as one of the major public health problems in the world. accurate identification of the dermatophytes species is important for recognition of the environment and animal sources of infection. in this survey, 1500 clinical specimens taken from outpatients suspected of dermatophytosis and they were examined by direct microscopy and culture. | 2016 | 27496524 |
| epidemiological aspects of dermatophytosis in khuzestan, southwestern iran, an update. | dermatophytosis is among the most common superficial mycoses in iran. the purpose of this report was to update the clinical and mycological features of human dermatophytosis in the khuzestan, southwestern iran. in the framework of a one-year survey, a total of 4120 skin, hair and nail samples obtained from the outpatients with symptoms suggestive of tinea were analyzed by using direct microscopy, culture and molecular identification methods. strains isolated from cultures were subjected to ampli ... | 2016 | 26886443 |
| phylogenetic analysis of dermatophyte species using dna sequence polymorphism in calmodulin gene. | use of phylogenetic species concepts based on rdna internal transcribe spacer (its) regions have improved the taxonomy of dermatophyte species; however, confirmation and refinement using other genes are needed. since the calmodulin gene has not been systematically used in dermatophyte taxonomy, we evaluated its intra- and interspecies sequence variation as well as its application in identification, phylogenetic analysis, and taxonomy of 202 strains of 29 dermatophyte species. a set of primers wa ... | 2016 | 26868901 |
| the anti-dermatophyte activity of commiphora molmol. | commiphora molmol engl (burseraceae) or myrrh has been traditionally used for the treatment of skin fungal infections. | 2016 | 26427766 |