| detection of dermatophytes in healthy companion dogs and cats in eastern india. | in recent times increasing occurrence of dermatophytosis, especially among the school children in eastern india was evidenced along with increased tendency of keeping companion animals such as dogs and cats. this study was undertaken to detect the occurrence of dermatophytes with antifungal susceptibility among the companion animals. a total of 1501 healthy companion animals comprising 1209 dogs and 292 cats belonged to individual owners in and around kolkata (west bengal, india) were examined f ... | 2016 | 27656224 |
| melokhanines a-j, bioactive monoterpenoid indole alkaloids with diverse skeletons from melodinus khasianus. | the new melokhanines a-j (1-10) and 22 known (11-32) alkaloids were isolated from the twigs and leaves of melodinus khasianus. the new compounds and their absolute configurations were elucidated by extensive analysis of spectroscopic, x-ray diffraction, and computational data. melokhanine a (1), composed of a hydroxyindolinone linked to an octahydrofuro[2,3-b]pyridine moiety, is an unprecedented monoterpenoid indole alkaloid. melokhanines b-h (2-8) possess a new 6/5/5/6/6 pentacyclic indole alka ... | 2016 | 27584856 |
| [evolution of tinea capitis observed in mycology laboratory of institute pasteur of algeria from1995 to 2015]. | tinea capitis are common in algeria and are a frequent reason for consultation. this mycosis affects children and rarely adults. this is a retrospective study over a period of 20 years from 1995 to 2015 at the mycology laboratory of the pasteur institute of algeria. | 2016 | 27554867 |
| diagnostic performance of molecular and conventional methods for identification of dermatophyte species from clinically infected arabian horses in egypt. | rapid and accurate identification of dermatophytes is crucial for the effective control of disease outbreaks. current methods based on culture and microscopic characteristics may require weeks before positive identification is made. | 2016 | 27549079 |
| [tinea in the genital area : a diagnostic and therapeutic challenge]. | pubogenital tinea or tinea genitalis represents a rare type of dermatophytosis which, however, is increasingly being diagnosed. the mons pubis is affected, but also the outer regions to the penis shaft and the labia together with the groins. pubogenital tinea is a more superficial erythrosquamous type, but strong inflammatory dermatomycoses of the genital area as tinea genitalis profunda ranging to kerion celsi are observed. a total of 30 patients (14-63 years of age, 11 men and 19 women) with p ... | 2016 | 27488308 |
| prevalence of tinea capitis among school children in nok community of kaduna state, nigeria. | in recent years, the prevalence of tinea capitis, an infection of the scalp by dermatophytes, has increased in children worldwide. this cross-sectional study was carried out to determine the prevalence and risk factor of tinea capitis among school children in nok community of kaduna state, nigeria. a total of 100 children were screened and 45% were diagnosed to have tinea capitis after fungal culture and microscopy. the prevalence of tinea capitis among girls was higher (51.4%) than that among b ... | 2016 | 27471603 |
| antifungal effects of the biological agent pythium oligandrum observed in vitro. | dermatophytosis, commonly known as ringworm, is a superficial fungal skin disease and zoonosis. pythium oligandrum is a micromycete with mycoparasitic properties that is used in agriculture to control fungal infections on plants. formulations containing p oligandrum were also developed for the treatment of dermatophytoses, but only several case studies have been published. in order to document the process in simplified conditions in vitro, we investigated the effectiveness of p oligandrum agains ... | 2016 | 27418287 |
| antifungal activity of cleome gynandra l. aerial parts for topical treatment of tinea capitis: an in vitro evaluation. | cleome gynandra l. (capparaceae) is an edible weed used in uganda topically for its presumed antifungal activity against tinea capitis. the goal of this study was to determine if this plant possesses antifungal activity in vitro, since t. capitis is a pervasive infection among especially rural children. | 2016 | 27391957 |
| evaluation of dermoscopy in the diagnosis of naturally occurring dermatophytosis in cats. | a rapid, accurate screening test for dermatophytosis in cats is desirable in clinical and shelter medicine. in human dermatology, dermoscopy is used to identify dermatophyte-infected hairs by their characteristic comma hair appearance. similar "comma-like" hairs have been observed in infected cats. | 2016 | 27311364 |
| in vitro evaluation of antifungal susceptibility and keratinase, elastase, lipase and dnase activities of different dermatophyte species isolated from clinical specimens in iran. | the aims of this study were to evaluate the enzymatic activity of various dermatophyte species and their antifungal susceptibility profiles. a total of 60 dermatophyte isolates, including trichophyton mentagrophytes, trichophyton rubrum, microsporum canis and microsporum gypseum, were examined. fungal isolates were analysed for the production of keratinase, lipase, elastase and deoxyribonuclease (dnase). a broth microdilution method was performed on the basis of m38-a2 clinical and laboratory st ... | 2016 | 27291045 |
| anti-fungal potential of ozone against some dermatophytes. | dermatophytes are classified in three genera, epidermophyton, microsporum and trichophyton. they have the capacity to invade keratinized tissue to produce a cutaneous infection known as dermatophytoses. this investigation was performed to study the effect of gaseous ozone and ozonized oil on three specific properties of six different dermatophytes. these properties included sporulation, mycelia leakage of sugar and nutrients and the activity of their hydrolytic enzymes. generally, ozonized oil w ... | 2017 | 27287337 |
| invasive microsporum canis causing rhinitis and stomatitis in a cat. | microsporum canis is a pathogenic fungus that typically causes dermatophytosis in cats. this report describes a cat with a microsporum canis infection causing invasive fungal rhinitis that extended through the hard palate, resulting in adjacent stomatitis. treatment with itraconazole and terbinafine resolved the infection. | 2016 | 27061928 |
| antifungal activity of cymbopogon nardus (l.) rendle (citronella) against microsporum canis from animals and home environment. | dermatophytosis is a common zoonosis in urban centers. dogs and cats have played an important role as its disseminators. environmental decontamination is essential for the prevention of its propagation to humans and animals. however, sanitizers or disinfectants with antifungal activity, currently available, have high toxicity. the present study evaluated the in vitro effects of an extract of citronella (cymbopogon nardus) on 31 microsporum canis isolates from animals and home environments. susce ... | 2015 | 27049705 |
| detection and characterization of zoonotic dermatophytes from dogs and cats in and around kolkata. | the ringworms of pet dogs, cats, and stray animals (dogs, cats, and other animals) could be a potential source of zoonotic infections causing a serious public health problem in the busy city kolkata. the pet owners are more susceptible to get this infection from their pets, because of the close contact with them as dermatophytosis is very much prevalent in those pets. so, this study was aimed to check the prevalence of dermatophytosis in dogs, cats, and in pet owners. | 2015 | 27047202 |
| decontamination of carpet exposed to microsporum canis hairs and spores. | objectives the objective of this study was to evaluate the efficacy of vacuuming and three carpet cleaning methods for the removal of microsporum canis spores and hairs from experimentally contaminated carpets. methods sterile berber carpeting was artificially contaminated with naturally infective m canis hairs and spores. carpet swatches were vacuumed for 10 s, 30 s and 60 s, and then cultured. three carpet cleaning methods were evaluated on area rugs experimentally contaminated with infective ... | 2017 | 26927817 |
| overexpression of tlr-2 and tlr-4 mrna in feline polymorphonuclear neutrophils exposed to microsporum canis. | polymorphonuclear neutrophils (pmns), along with macrophages, are the first leukocytes recruited to the site of infection in dermatophytoses and are responsible for the in fine elimination of the fungus. it has been demonstrated that feline pmns produce pro-inflammatory cytokines after stimulation with microsporum canis. the activation of these cells results from the recognition of specific pamps (pathogen associated molecular patterns) from m. canis by prrs (pattern recognition receptors) of pm ... | 2016 | 26914839 |
| tinea faciei caused by trichophyton mentagrophytes in a 20-day-old neonate. | although candidiasis in newborns is not uncommon, superficial dermatophyte infections of infants is quite rare. the causative agents of neonatal tinea reported in various case studies have been trichophyton rubrum, microsporum canis, microsporum gypseum, and trichophyton violaceum. to the best of our knowledge, no case report of neonatal tinea faciei caused by trichophyton mentagrophytes has been reported earlier. | 2015 | 26904450 |
| epidemiology of superficial fungal infections in guangdong, southern china: a retrospective study from 2004 to 2014. | superficial fungal infections are common worldwide; however, the distribution of pathogenic species varies among geographical areas and changes over time. this study aimed to determine the epidemiologic profile of superficial fungal infections during 2004-2014 in guangzhou, southern china. data regarding the superficial mycoses from outpatients and inpatients in our hospital were recorded and analyzed. from the 3367 patients that were enrolled in the study, 3385 samples were collected from skin, ... | 2016 | 26883512 |
| determining the pathogenic potential of non-sporulating molds isolated from cutaneous specimens. | although non-sporulating molds (nsm) are frequently isolated from patients and have been recognized as agents of pulmonary disease, their clinical significance in cutaneous specimens is relatively unknown. therefore, this study aimed to identify nsm and to determine the keratinolytic activity of isolates from cutaneous sites. nsm isolates from clinical specimens such as skin, nail, and body fluids were identified based on their ribosomal dna sequences. of 17 nsm isolates (7 ascomycota, 10 basidi ... | 2016 | 26847667 |
| in vitro efficacy of shampoos containing miconazole, ketoconazole, climbazole or accelerated hydrogen peroxide against microsporum canis and trichophyton species. | objectives the objective was to evaluate the antifungal efficacy of shampoo formulations of ketoconazole, miconazole or climbazole and accelerated hydrogen peroxide wash/rinse against microsporum canis and trichophyton species spores. methods lime sulfur (1:16)-treated control, enilconazole (1:100)-treated control, accelerated hydrogen peroxide (ahp 7%) 1:20 and a 1:10 dilution of shampoo formulations of miconazole 2%, miconazole 2%/chlorhexidine gluconate 2-2.3%, ketoconazole 1%/chlorhexidine 2 ... | 2017 | 26809882 |
| synthesis, biological evaluation and molecular docking of certain sulfones as potential nonazole antifungal agents. | we reported herein the synthesis, antifungal activity, docking and in silico adme prediction studies of four novel series of sulfones 6a-f, 8a-c, 10a-f and 12a-c. all the newly synthesized sulfones were tested against four strains of candida (including fluconazole-resistant candida), two strains of aspergillus, two dermatophytic fungi (trichophytons mentagrophyte and microsporum canis) and syncephalastrum sp. with fluconazole as a reference drug. in general, compounds 8a and 10b showed selective ... | 2016 | 26805791 |
| ailanthus altissima (miller) swingle fruit - new acyl β-sitosteryl glucoside and in vitro pharmacological evaluation. | β-sitosterol-3-o-(6'-o-13"-octadecenoyl)-β-d-glucoside (1), a new acyl β-sitosteryl glucoside, along with three known compounds β-sitosterol-3-o-β-d-glucoside (2), β-sitosterol (3) and methyl gallate (4) have been isolated from the ethyl acetate soluble fraction of methanolic extract of ailanthus altissima fruits. their structures were elucidated through spectroscopic data including 2d nmr, esi-ms, methanolysis and oxidative cleavage of double bond. antibacterial, antifungal, cytotoxic, phytotox ... | 2016 | 26795253 |
| an open-field study comparing an essential oil-based shampoo with miconazole/chlorhexidine for hair coat disinfection in cats with spontaneous microsporiasis. | the goal of the present study was to compare the antifungal efficacy of an essential oil (eo) shampoo proven to be effective against microsporum canis with miconazole/chlorhexidine for topical hair coat disinfection in cats treated concurrently with oral itraconazole. | 2016 | 26783019 |
| [tinea capitis in the military hospital avicenna (morocco): review of 8 years (2006-2013)]. | tinea capitis are due to fungal infection by dermatophytes. they are common in developing countries including morocco. the objective of this study intended to describe the epidemiology, clinical and mycological profile of tinea capitis in avicenna military hospital of marrakech. | 2016 | 26778722 |
| chemical composition and antifungal activity of essential oil from eucalyptus smithii against dermatophytes. | in this study, we evaluated the chemical composition of a commercial sample of essential oil from eucalyptus smithii r.t. baker and its antifungal activity against microsporum canis atcc 32903, microsporum gypseum atcc 14683, trichophyton mentagrophytes atcc 9533, t. mentagrophytes atcc 11480, t. mentagrophytes atcc 11481, and trichophyton rubrum cct 5507. | 2015 | 26676500 |
| increased circulating th17 cell in a patient with tinea capitis caused by microsporum canis. | | 2016 | 26666478 |
| [a recurrent case of adult favus successfully treated with terbinafine]. | favus or tinea capitis favosa, is a chronic inflammatory dermatophytosis of the scalp. the disease is particularly common in children aged 6 to 10 years, more often in boys, and it also occurs in adults. human-to-human transmission is therefore possible. anthropophilic trichophyton schöenleinii is responsible for over 95% of favus cases. in addition, there are rare cases of anthropophilic t.violaceum, zoophilic (t.verrucosum, t.quinckeanum, and microsporum canis) and geophilic m.gypseum species ... | 2015 | 26649420 |
| tinea corporis, caused by microsporum canis - a case report from kosovo. | tinea corporis (b35.6) caused by microsporum canis which is fungal species that causes numerous forms of disease. it is part of a group of fungi known as dermatophytes. though mostly well known for ringworm in pets, it is also known to infect humans. this fact makes this pathogen both anthrophilic and zoophilic in nature. microsporum canis is a communicable pathogen. | 2015 | 26622092 |
| essential oil of algerian eucalyptus citriodora: chemical composition, antifungal activity. | essential oil of eucalyptus citriodora is a natural product which has been attributed for various medicinal uses. in the present investigation, e. citriodora essential oil was used to evaluate its antifungal effect against medically important dermatophytes. | 2015 | 26597375 |
| advances in microbiology, infectious diseases and public health: fungal occurrence in the hair and skin of symptomatic pets in turin, italy. | companion animals, often asymptomatic reservoir of fungi, can be important sources of infection in humans, due to the close contact with their owners. the present study was aimed to assess the occurrence of dermatophytes and other fungi isolated from pet dermatological lesions in turin, italy. dermatological specimens were examined for fungal elements by direct microscopy and cultured to detect dermatophytes, other filamentous fungi and yeasts: 247 pets (118 cats, 111 dogs and 18 dwarf rabbits) ... | 2016 | 26563306 |
| administration of oral itraconazole capsule with whole milk shows enhanced efficacy as supported by scanning electron microscopy in a child with tinea capitis due to microsporum canis. | although diagnosis and treatment of tinea capitis in children are not difficult, treatment failures are still somewhat common. we report a case of pediatric tinea capitis cured using oral itraconazole administered with whole milk, after prior treatment failure when oral itraconazole was administered with water. this apparent enhanced efficacy in one individual was demonstrated using scanning electron microscopy. | 2015 | 26447934 |
| [microsporum canis: current data on the prevalence of the zoophilic dermatophyte in central germany]. | microsporum (m.) canis, whose source of infection is mostly cats, is still considered as the most frequently occurring zoophilic dermatophyte in germany and europe. in distinct areas of germany, the zoophilic dermatophyte trichophyton (t.) anamorph of arthroderma (a.) benhamiae also presents a frequent and emerging causative agent of dermatophytoses. | 2015 | 26446665 |
| in vitro activity of twenty commercially available, plant-derived essential oils against selected dermatophyte species. | the in vitro activity of twenty chemically defined essential oils (eos) obtained from boswellia sacra, citrus bergamia, c. limon, c. medica, cinnamomum zeylanicum, eucalyptus globulus, foeniculum vulgare, helichrysum italicum, illicium verum, litsea cubeba, mentha spicata, myrtus communis, ocimum basilicum, origanum majorana, o. vulgare, pelargonium graveolens, rosmarinus officinalis, santalum album, satureja montana, and thymus serpyllum was assayed against clinical animal isolates of microspor ... | 2015 | 26434145 |
| the anti-dermatophyte activity of commiphora molmol. | commiphora molmol engl (burseraceae) or myrrh has been traditionally used for the treatment of skin fungal infections. | 2016 | 26427766 |
| evaluation of two molecular techniques for rapid detection of the main dermatophytic agents of tinea capitis. | tinea capitis is very common in western china, with the most widespread aetiological agent being trichophyton violaceum, while microsporum canis is prevalent in the remainder of china. conventional diagnostics and internal transcribed spacer (its) sequencing analyses have proven relatively limited due to the close phylogenetic relationship of anthropophilic dermatophytes. therefore, alternative molecular tools with sufficient specificity, reproducibility and sensitivity are necessary. | 2015 | 26342174 |
| dermatoscopic findings as a complementary tool in the differential diagnosis of the etiological agent of tinea capitis. | tinea capitis is a scalp infection caused by fungi. in brazil, the main causative agents are microsporum canis and the trichophyton tonsurans. etiological diagnosis is based on suggestive clinical findings and confirmation depends on the fungus growth in culture. however, it is not always possible to perform this test due to lack of availability. we reveal the dermoscopic findings that enable distinction between the main causative agents of tinea capitis, m. canis and t. tonsurans. the associati ... | 2015 | 26312662 |
| epidemiological changes in tinea capitis over the sixty years of economic growth in china. | tinea capitis is a fungal infection of the scalp occurring commonly in children. historical data indicate that clinical manifestations and the spectrum of etiologic agents vary greatly with geography, as well as socioeconomic affected populations. | 2015 | 26260745 |
| griseofulvin and fluconazole reduce transmission of tinea capitis in schoolchildren. | we evaluated the efficacy of griseofulvin and fluconazole in reducing the potential for person-to-person transmission of tinea capitis (tc) in children. | 2015 | 26215468 |
| [keratinophilic fungi in soils of parks of corrientes city, argentina]. | the soil is a natural reservoir of keratinophilic fungi, which are a small but important group of filamentous fungi, some of which typically develop on keratinized tissues of living animals. there are numerous species of saprophytic fungi with recognized keratinophilic abilities, and several studies have been undertaken in order to link their presence to possible human disease. | 2016 | 26112435 |
| in vitro and in vivo antidermatophytic activities of some iranian medicinal plants. | in the last decades, the number of people suffering from dermatophytoses has seriously increased, which may be due to the development of resistant strains to a range of antifungal drugs. the present study was aimed to evaluate the antidermatophytic properties of eight extracts from the selected spices and herbs, which were ethno-medicinally used in iran against trichophyton mentagrophytes, trichophyton interdigitale, microsporum canis, and microsporum gypseum (10 strain of each). the in vitro an ... | 2015 | 26092105 |
| in vitro evaluation of enzymatic and antifungal activities of soil-actinomycetes isolates and their molecular identification by pcr. | human cutaneous infection caused by a homogeneous group of keratinophilic fungi called dermatophytes. these fungi are the most common infectious agents in humans that are free of any population and geographic area. microsporum canis is a cause of dermatophytosis (tinea) in recent years in iran and atypical strain has been isolated in iran. its cases occur sporadically due to m. canis transmission from puppies and cats to humans. since this pathogenic dermatophyte is eukaryotes, chemical treatmen ... | 2015 | 26060560 |
| antifungal activity of berberine hydrochloride and palmatine hydrochloride against microsporum canis -induced dermatitis in rabbits and underlying mechanism. | phellodendron amurense, exhibits antifungal activity mainly by bioactive components including berberine hydrochloride and palmatine hydrochloride. this study was conducted to evaluate the antifungal effects of berberine hydrochloride, palmatine hydrochloride, and a mixture of both substances against microsporum canis in vivo and in vitro. | 2015 | 26054937 |
| decontamination of laundry exposed to microsporum canis hairs and spores. | the objective of this study was to determine the efficacy of decontamination of fabric exposed to microsporum canis hairs and spores by mechanical washing using hot or cold water with or without a sodium hypochlorite additive, and to field test a washing protocol for terry cloth and denim exposed to m canis via direct contact with infected cats. | 2016 | 26012868 |
| dermoscopic features in 12 cats with dermatophytosis and in 12 cats with self-induced alopecia due to other causes: an observational descriptive study. | dermoscopy is a noninvasive technique allowing rapid magnified in vivo observation of the skin and structures that lie beneath the skin surface. various congenital and acquired hair shaft abnormalities may also be evaluated by dermoscopy. additionally, characteristic features of microsporum canis-induced tinea capitis and trichotillomania in humans have been reported. | 2015 | 25988302 |
| tinea capitis caused by microsporum canis infection in a 75-year-old woman. | | 2015 | 25876151 |
| digital gene expression analysis of microsporum canis exposed to berberine chloride. | berberine, a natural isoquinoline alkaloid of many medicinal herbs, has an active function against a variety of microbial infections including microsporum canis (m. canis). however, the underlying mechanisms are poorly understood. to study the effect of berberine chloride on m. canis infection, a digital gene expression (dge) tag profiling was constructed and a transcriptome analysis of the m. canis cellular responses upon berberine treatment was performed. illumina/hisseq sequencing technique w ... | 2015 | 25874937 |
| susceptibility of microsporum canis arthrospores to a mixture of chemically defined essential oils: a perspective for environmental decontamination. | the zoophilic dermatophyte microsporum canis has cats as natural reservoir, but it is able to infect a wide range of hosts, including humans, where different clinical features of the so-called ringworm dermatophytosis have been described. human infections are increasingly been reported in mediterranean countries. a reliable control program against m. canis infection in cats should include an antifungal treatment of both the infected animals and their living environment. in this article, a herbal ... | 2015 | 25854840 |
| updating the epidemiology of dermatophyte infections in palestine with special reference to concomitant dermatophytosis. | to determine the epidemiology of dermatophytosis in palestinian patients, detect changes in the etiological agents during the last three decades, and to correlate between concomitant tinea pedis infections, and other cutaneous lesions. | 2015 | 25835157 |
| kennel disinfectants for microsporum canis and trichophyton sp. | the antifungal efficacy of commonly used kennel disinfectants for large surfaces was tested using naturally infective material from untreated animals (m. canis and trichophyton sp.) soaked and macerated but unfiltered leaving visible fluorescing hairs and/or scales in the test inoculum to create a robust challenge. disinfectants included sodium hypochlorite (1 : 32 and 1 : 100), enilconazole (1 : 100), accelerated hydrogen peroxide (1 : 16), potassium peroxymonosulfate (1% and 2%), and calcium h ... | 2015 | 25763290 |
| incidence and etiological agents of genital dermatophytosis in males. | to determine the incidence and etiological agents of dermatophytosis of male genitalia in sarajevo area, bosnia and herzegovina, during a 5-year period (2009-2013). | 2015 | 25669337 |
| clinical features of 80 cases of tinea faciei treated at a rural clinic in japan. | from march 2008 through february 2014, 80 patients aged 1-95 years (43 men and 37 women) were diagnosed with tinea faciei by a rural japanese clinic. the affected sites were the cheek in 42 patients (52.5%), the auricles and area surrounding the auricles in 16 (20.0%), and the mandible in 12 (15.0%); 33 patients (41.2%) had concurrent ringworm in areas other than the face. twenty-one patients (26.3%) had applied topical steroids to treat a rash. the pathogen responsible for tinea faciei was tric ... | 2014 | 25639303 |
| phytochemical characterization, antimicrobial activity, and antioxidant potential of equisetum hyemale l. (equisetaceae) extracts. | equisetum hyemale species is considered a medicinal plant used in the form of infusions to combat infectious or inflammation diseases and also diuretic effects, presenting several compounds related to these actions. in previous studies different species of equisetum showed several phenolic compounds. the objective of this study was, for the first time, based on phytochemistry analysis to evaluate the antioxidant and antimicrobial activity. the 70% ethanolic and methanolic extracts of e. hyemale ... | 2015 | 25587637 |
| phenotypical and molecular characterization of microsporum canis strains in north-tunisia. | in this study, 40 microsporum canis isolates were obtained from different patients from the mycology unit of the hospital la rabta (tunis) during a 3 month period. the phenotypic identification was done by morphological characterization and biochemical tests. molecular analysis was performed by amplification of the its region of rdna, the amplified region was subjected to enzymatic digestion and sequenced to evaluate phylogenetic relationships. the morphological analysis showed a considerable di ... | 2014 | 25546941 |
| application of microsatellite-primed pcr (msp-pcr) and pcr melting profile (pcr-mp) method for intraspecies differentiation of dermatophytes. | in this study, two pcr-based methods (msp-pcr and pcr-mp) were compared for their abilities to identify intraspecies variations of 23 isolates of trichophyton rubrum, 78 isolates of trichophyton interdigitale and 22 isolates of microsporum canis, obtained mainly from patients in lódź city. the results allowed to distinguish four types (containing two subtypes) characteristic for t. interdigitale and three types characteristic for t. rubrum using pcr-mp method. analysis conducted using msp-pcr wi ... | 2014 | 25546938 |
| assessment of immunogenicity and protective efficacy of microsporum canis secreted components coupled to monophosphoryl lipid-a adjuvant in a vaccine study using guinea pigs. | microsporum canis is the most common dermatophyte in pets and is of zoonotic importance but currently there is no effective vaccine available to prevent dermatophytosis. the aim of this work was to assess the immunogenicity and protective efficacy of secreted components (sc) from m. canis adjuvanted with the monophosphoryl lipid-a (mpla), in a vaccine study using the guinea pig as an experimental model. animals were vaccinated with either the sc adjuvanted with the mpla, the mpla adjuvant alone ... | 2015 | 25532779 |
| synthesis and fungistatic activity of aryl aldoxime derivatives. | the antifungal activity of 13 arylaldoxime ester and ether derivatives was tested against 4 dermatophytes trichophyton mentagrophytes (tm), microsporum canis (mc); m. cookei, and m. gypseum. | 2015 | 25499806 |
| newly described features resulting from high-magnification dermoscopy of tinea capitis. | recent studies have reported "comma hairs" as a typical dermoscopic feature of tinea capitis observed at low magnification (×10). the aim of this study was to evaluate the dermoscopic aspects of tinea capitis at high magnification (×150) and its diagnostic role. | 2015 | 25471133 |
| the anti-dermatophyte activity of allium hirtifolium boiss aqueous extract. | in an attempt at demonstrating the efficacy of allium hirtifolium aqueous extract in control of skin fungal infections as traditional use, we evaluated the anti-dermatophyte activities of a. hirtifolium aqueous extract from bulbs and of ketoconazole against trichophyton rubrum, trichophyton mentagrophytes, microsporum canis, m. gypseum, trichophyton schoenleinii and trichophyton verrucosum var. album by food poisoning technique, disc diffusion and micro broth dilution assays. the anti-fungal act ... | 2015 | 25456419 |
| evaluation of antifungal activities of the essential oil and various extracts of nigella sativa and its main component, thymoquinone against pathogenic dermatophyte strains. | plant extracts and plant-derived compounds are valuable sources as folk medicine for the treatment and prevention of a wide range of diseases including infectious diseases. in the present study, the antifungal activities of the essential oil and various extracts nigella sativa and its active principle, thymoquinone against trichophyton mentagrophytes, microsporum canis and microsporum gypseum as pathogenic dermatophyte strains have been evaluated. in addition, the cytotoxic effects of n. sativa ... | 2014 | 25442918 |
| antifungal activity of pomegranate peel extract and isolated compound punicalagin against dermatophytes. | dermatophyte species infect the epidermis and appendages, often with serious social and health-economic consequences. the hydroalcoholic extract of pomegranate fruit peel showed activity against the dermatophyte fungi trichophyton mentagrophytes, t. rubrum, microsporum canis and m. gypseum. | 2014 | 25260038 |
| management of endemic microsporum canis dermatophytosis in an open admission shelter: a field study. | endemic microsporum canis dermatophytosis was identified in a large, open admission, private, no-kill shelter that admitted >1200 cats per year. fungal culture (fc) screening revealed that 166/210 (79%) and 38/99 (38%) cats in the non-public and public area were culture positive, respectively. however, pending screening fc results, the 99 cats in the public area were treated with once-weekly lime sulfur rinses and monitored with once-weekly fc. cats in the non-public area were not treated. when ... | 2015 | 25074567 |
| multiorgan fungal infection caused by microsporum canis in a green iguana (iguana iguana). | multiple organ invasion by keratinophilic fungi in the green iguana (iguana iguana) has not been previously reported. in this case, a 1-yr-old female green iguana presented with a nodular, darkly discolored skin lesion surrounded by necrosis in the right ventral abdominal region. a cytologic examination of the fine needle aspiration of the lesion revealed an exuberant proliferation of fibroblasts, macrophages, and multinucleated cells along with frequent filamentous structures consistent with hy ... | 2014 | 25000705 |
| tinea capitis caused by microsporum canis infection in a 75-years-old woman. | | 2014 | 24990278 |
| trichophyton species of arthroderma benhamiae - a new infectious agent in dermatology. | in germany, infections due to the zoophilic dermatophyte trichophyton (t.) species of arthroderma benhamiae are being more frequently diagnosed. the source of infection of this emerging pathogen overlaps with that of the zoophilic species t. interdigitale. the most common source are guinea pigs. t. species of arthroderma benhamiae causes inflammatory dermatophytosis in children and adolescents. in addition to tinea capitis, it may cause both tinea corporis, tinea manus and frequently tinea facie ... | 2014 | 24981469 |
| fingertip contamination after a brief touch of tinea capitis lesions caused by microsporum canis. | | 2015 | 24975367 |
| identification of dermatophytes by polymerase chain reaction-restriction fragment length polymorphism analysis of metalloproteinase-1. | transgenic research on metalloproteinase-1 is an emerging field in the area of plant molecular biology. the new method reported here can similarly be applied in fungal molecular biology to identify different dermatophytes. our method is more accurate than traditional methods such as molecular analyses. | 2014 | 24966633 |
| survey of dermatophytes in stray cats with and without skin lesions in northern italy. | the aim of this study was to determine the prevalence of dermatophytes in stray cats with and without clinical lesions from different colonies in rural and urban areas of milan and surroundings in northern italy. stray cats (273) were caught during a trap-neuter-release (tnr) program conducted in different colonies of northern italy in both rural and urban areas. each cat was examined in dark environment with a wood's lamp prior to sample collection. hair or scales exhibiting typical fluorescenc ... | 2014 | 24955280 |
| the use of a one-step pcr method for the identification of microsporum canis and trichophyton mentagrophytes infection of pets. | dermatophytes are a closely related group of keratinophilic fungi. they encompass important etiological agents of superficial fungal infections. these fungi are able to invade keratinized tissues of humans and animals, causing dermatophytosis (ringworm) of hair, nails or skin. | 2014 | 24945136 |
| some characteristics of tinea capitis. | | 2013 | 24910754 |
| poly(ethylene glycol)-block-poly(ε-caprolactone) nanomicelles for the solubilization and enhancement of antifungal activity of sertaconazole. | sertaconazole nitrate is a broad spectrum imidazole antifungal agent with antibacterial and anti-inflammatory properties. however, its lipophilic nature and very poor aqueous solubility limit its use in the clinic. the aim of this study was to develop and characterize poly(ethylene glycol)-block-poly(ε-caprolactone) (peg-b-pcl) polymeric nanomicelles for the solubilization and enhancement of sertaconazole antifungal activity. sertaconazole was incorporated into peg-b- pcl polymeric nanomicelles ... | 2014 | 24909149 |
| [evaluation of the in vitro susceptibility pattern of clinical isolates of trichophyton mentagrophytes and trichophyton rubrum in santiago, chile]. | dermatophytes are a group of keratinophilic fungi able to produce dermatophytosis or tinea infections. in chile, trichophyton rubrum and trichophyton mentagrophytes are the ones most commonly isolated in adults, while microsporum canis is found among children. treatment of these infections is usually with topical or oral antifungals, such as griseofulvin or azole derivatives (clotrimazole, itraconazole, fluconazole), allylamines (terbinafine) or new drugs that are available. | 2015 | 24794211 |
| [dermatophytes transmitted by pets and cattle]. | most inflammatory skin and hair dermatophytoses are caused by one of four zoophilic dermatophyte species: microsporum canis (from cats and dogs), trichophyton verrucosum (from cattle), arthroderma benhamiae (from guinea-pigs) and arthrodermna vanbreuseghemii (generally from cats and dogs). in cases of highly inflammatory tinea corporis, tinea faciae and tinea capitis in humans, it is important to identify with certainty the precise etiologic agent and to examine pets as the possible source of in ... | 2014 | 24772808 |
| [epidemiology of tinea capitis in the suburbs of tipasa, algeria]. | tinea capitis represent a public health problem in algeria, despite improvement of living conditions. we conducted a retrospective study of cases diagnosed in the hospital hadjout (tipasa), algeria, during 3 years (january 2010-january 2013). | 2014 | 24746723 |
| potential effects of trachyspermum copticum essential oil and propolis alcoholic extract on mep3 gene expression of microsporum canis isolates. | the purpose of this study was to evaluate the effects of trachyspermum copticum (t. copticum) essential oil and propolis alcoholic extract on growth and transcription of mep3 gene of microsporum canis (m. canis) strains. | 2014 | 24746722 |
| in vitro activity of the protegrin ib-367 alone and in combination compared with conventional antifungal agents against dermatophytes. | the occurrence of resistance or side effects in patients receiving antifungal agents leads to failure in the treatment of mycosis. the aim of this experimental study was to investigate the in vitro effects of ib-367 alone and in combination with three standard antifungal drugs, fluconazole (flu), itraconazole (itra) and terbinafine (terb), against 20 clinical isolates of dermatophytes belonging to three species. minimum inhibitory concentrations (mics), minimal fungicidal concentrations (mfcs), ... | 2014 | 26058322 |
| comparative study of microsporum canis isolates by dna fingerprinting. | microsporum canis is a zoophilic fungus and it is an important agent of dermatophytosis. cats act as important reservoirs. clinically, it is too difficult to differentiate dermatophytosis caused by various species, also this fungus loses its morphological characteristics easily because of subculture; so using of rapid and accurate laboratory techniques for identifying the dermatophytes is important, therefore, rapd-pcr was applied for the differentiation of the isolates. in this study, 10 m. can ... | 2014 | 24635009 |
| efficacy of disinfectants containing accelerated hydrogen peroxide against conidial arthrospores and isolated infective spores of microsporum canis and trichophyton sp. | accelerated hydrogen peroxide is a proprietary disinfectant formulation that is available for both commercial and home use and is labelled as antifungal. | 2014 | 24617995 |
| the effect of microwave irradiation on the vitality of various dermatophytes. | dermatomycosis is one of the most common dermatological infectious diseases. in recent years, the incidence of tinea pedum, a fungal infection of the feet, was increasing due to changing lifestyles. the risk of tinea pedum infections is associated with the use of sport shoes as well as contact with public sports facilities. transmission of dermatomycosis occurs almost exclusively through indirect contacts, meaning that contagious material initially contaminates the patients' environment and subs ... | 2014 | 24612041 |
| identification of dermatophyte species using genomic in situ hybridization (gish). | a genomic in situ hybridization (gish)-based method for dermatophyte identification has been developed. using specific gish probes, discrimination between trichophyton interdigitale, trichophyton rubrum and microsporum canis has been conducted. moreover, gish has been found particularly helpful when proper dermatophyte identification was difficult due to ambiguous pcr-rflp patterns. | 2014 | 24589627 |
| an outbreak of microsporum canis in two elementary schools in a rural area around the capital city of slovenia, 2012. | an outbreak of microsporum canis infection affected 12 persons in two elementary schools over a period of 48 days in 2012 in slovenia. epidemiological, microbiological, and animal investigations were conducted. we defined cases as pupils or employees with skin lesions and confirmed or probable m. canis infection, attending one of the implicated elementary schools. two clusters of six primary and six secondary cases were included in an unmatched case-control study. contact with an adopted stray k ... | 2014 | 24512846 |
| pathogenic fungus microsporum canis activates the nlrp3 inflammasome. | microsporum canis is a pathogenic fungus with worldwide distribution that causes tinea capitis in animals and humans. m. canis also causes invasive infection in immunocompromised patients. to defy pathogenic fungal infection, the host innate immune system is the first line of defense. as an important arm of innate immunity, the inflammasomes are intracellular multiprotein complexes that control the activation of caspase-1, which cleaves proinflammatory cytokine pro-interleukin-1β (il-1β) into it ... | 2014 | 24478101 |
| antifungal potential of essential oil and ethanol extracts of lonicera japonica thunb. against dermatophytes. | the antifungal potential of essential oil and ethanolic leaf extracts of lonicera japonica thunb. was evaluated for controlling the growth of dermatophytes. the oil (1,000 ppm) and extracts (1,500 ppm) of l. japonica revealed 55.1-70.3 % and 40.1-65.5 % antidermatophytic effect against microsporum canis kctc 6348, 6349, 6591, trichophyton rubrum kctc 6345, 6352, 6375, trichophyton mentagrophytes kctc 6077 and 6085, respectively, along with their respective minimum inhibitory concentrations rangi ... | 2014 | 26417269 |
| [in vitro antifungal activity of ravuconazole against isolates of dermatophytes and candida species from patients with dermatomycoses]. | the in vitro activity of ravuconazole (rvcz) was compared with those of itraconazole (itcz) and terbinafine (tbf) against 73 dermatophyte isolates and 18 candida spp. isolates recovered from patients with dermatomycosis at 4 dermatological clinics in japan in 2011. the dermatophyte isolates consisted of trichophyton rubrum (n=51), trichophyton mentagrophytes (n=20 : these strains were not identified by molecular phylogenetic analysis.), trichophyton tonsurans (n=1), and microsporum canis (n=1). ... | 2014 | 25742996 |
| evaluation of trace elements, oxidant/antioxidant status, vitamin c and β-carotene in dogs with dermatophytosis. | the aim of the study was to determine zinc, copper and iron levels, erythrocyte oxidant/antioxidant status, vitamin c and β-carotene in dogs with dermatophytosis. a total of 23 dogs with clinically established diagnosis of dermatophytosis by trichogram and positive fungal culture and six dogs as control were included in this study. on cultural examination 52.17% fungal isolates were found to be microsporum canis, 30.43% were trichophyton mentagrophytes and 17.39% were m. gypseum. in comparison t ... | 2014 | 24329950 |
| clinical specificities of tinea capitis in georgia population. | the aim of the study was to reveal peculiarities of the clinical symptoms and forms of tinea capitis caused by etiological agents that are common in our country. the study was conducted on 176 ambulatory patients who approached the national centre in 2009-2013. inclusion criterion was simultaneous presence of clinical symptoms and positive result of microscopic study. for cultural examination was used sabouraud's dextrose agar with the antibiotic chloramphenicol. clinical manifestations were div ... | 2013 | 24323960 |
| rapid detection for rabbit-derived dermatophytes using microsatellite-primed polymerase chain reaction. | a method exhibiting high sensitivity, specificity and rapidity to detect pathogenic dermatophytes was developed using microsatellite-primed polymerase chain reaction (pcr) in combination with a clustering method. the dna fragments of trichophyton mentagrophyton, microsporum gypseum and microsporum canis were amplified by using the primer (gaca)4 to detect the dna polymorphism fingerprints. twenty-one clinical strains identified as t. mentagrophyton, m. gypseum or m. canis by morphological method ... | 2014 | 24296862 |
| efficacy and safety of terbinafine hydrochloride 1% cream vs. sertaconazole nitrate 2% cream in tinea corporis and tinea cruris: a comparative therapeutic trial. | to the best of our knowledge, till date no study comparing the efficacy and safety of terbinafine hydrochloride 1% cream and sertaconazole nitrate 2% cream has been done in localized tinea corporis and tinea cruris. | 2013 | 24249898 |
| synthesis, spectral characterization, self-assembly and biological studies of n-acyl-2-pyrazolines bearing long alkoxy side chains. | a series of new pyrazoline derivatives (1b-4c) bearing n-acyl arms and nine to twelve carbon long alkoxy side chains was synthesized and characterized on the basis of spectroscopic data and microanalysis. the nature of self-assembly to understand the interplay of alkoxy chain crystallization and various supramolecular interactions was investigated using single crystal x-ray diffraction studies. interesting self-assembled supramolecular structures of 1b and 4c were observed in the crystal lattice ... | 2014 | 24177882 |
| antifungal activity of copaifera langsdorffii desf oleoresin against dermatophytes. | dermatophytoses are mycoses that affect keratinized tissues in both humans and animals. the aim of this study was to investigate the antifungal activity of the oleoresin extracted from copaifera langsdorffii desf. against the strains microsporum canis atcc 32903, microsporum gypseum atcc 14683, trichophyton mentagrophytes atcc 11481 and trichophyton rubrum cct 5507. the antimicrobial activity was determined by minimum inhibitory concentration (mic) and minimum fungicidal concentration (mfc) valu ... | 2013 | 24126374 |
| efficacy of eight commercial disinfectants against microsporum canis and trichophyton spp. infective spores on an experimentally contaminated textile surface. | an important part of treatment of dermatophytosis is the removal of infective material and decontamination of the environment. it is recognized that the role of disinfectants is to kill infective material not removed during the mechanical removal of debris and gross cleaning steps. a widely used disinfectant in the home is a dilute solution of sodium hypochlorite. | 2013 | 24102835 |
| treatment of shelter cats with oral terbinafine and concurrent lime sulphur rinses. | dermatophytosis is an important contagious and infectious skin disease in an animal shelter. itraconazole is the commonly used systemic antifungal drug, but it is expensive in some countries and, at times, difficult to obtain. terbinafine is a fungicidal allylamine with documented in vitro and in vivo efficacy against microsporum canis in pet cats and in cats with experimental infections. | 2013 | 24033387 |
| contact-free inactivation of trichophyton rubrum and microsporum canis by cold atmospheric plasma treatment. | cold atmospheric plasma (cap) has already proven efficient at disinfection of microorganisms including biofilms. the objective of the present study is to assess the efficacy of cap against the dermatophytes trichophyton rubrum and microsporum canis in vitro. | 2013 | 24020738 |
| [kerion caused by the zoophilic dermatophyte trichophyton species of arthroderma benhamiae in a child. a new emerging pathogen of dermatomycoses in germany]. | trichophyton (t.) species of arthroderma (a.) benhamiae is a new emerging pathogen of dermatomycoses in children and adolescents. this zoophilic fungus seems to be more common than other zoophilic dermatophytes, e. g. microsporum canis transmitted from cats to humans, zoophilic strains of t. interdigitale, and t. verrucosum as cause of ringworm of cattle. trichophyton species of a. benhamiae is transmitted from guinea pigs (cavia porcellus form. domestica) to human beings and causes highly infla ... | 2013 | 24008933 |
| susceptibility of clinically important dermatophytes against statins and different statin-antifungal combinations. | the investigation of the antifungal activities of drugs whose primary activities are not related to their antimicrobial potential is in the current forefront of research. statin compounds, which are routinely used as cholesterol-lowering drugs, may also exert direct antimicrobial effects. in this study, the in vitro antifungal activities of various statins (lovastatin, simvastatin, fluvastatin, atorvastatin, rosuvastatin and pravastatin) were examined against one isolate each of four dermatophyt ... | 2014 | 24004389 |
| [dermatophytosis diagnosed at the laboratory of parasitology and mycology of le dantec hospital in dakar between 2007 and 2011]. | dermatophytosis is a disease caused by dermatophytes, filamentous fungi adapted to human and animal keratin, colonizing and infecting human skin. the goal of this study was to identify dermatophytes responsible for dermatophytosis among patients, seeking for care in dakar. material and methods this study was carried out at the laboratory of parasitology and mycology at le dantec hospital, in senegal between june 2007 and december 2011, and included 2026 patients. | 2013 | 23988404 |
| cortisol levels in cats' hair in presence or absence of microsporum canis infection. | the purpose of this work was to perform a preliminary screening in the domestic cat to assess the concentration of cortisol in hairs by radioimmunoassay technique (ria) in presence or absence of microsporum canis infections. a total of 245 cats (7 with cutaneous lesions referable to dermatophytosis and 238 apparently healthy) coming from 14 shelters were examined. m. canis was isolated in 126 (51.4%) cats. the cortisol levels were significantly higher in cats with lesions or without lesions but ... | 2013 | 23962857 |
| microsporum canis infection in three familial cases with tinea capitis and tinea corporis. | we report a familial infection caused by microsporum canis. the first two patients were a 30-year-old female and her son, a 5-year-old boy, who came in contact with a pet dog at a farm house. the boy then suffered from hair loss for 3 months. there were circular and patchy alopecia with diffuse scaling on his scalp. meanwhile, his mother also developed patchy erythema and scaling on her face. several weeks later, the boy's sister, a 4-year-old girl, was noted to have inconspicuous scaly plaques ... | 2013 | 23918090 |
| dermatophytosis in cats: abcd guidelines on prevention and management. | dermatophytosis, usually caused by microsporum canis, is the most common fungal infection in cats worldwide, and one of the most important infectious skin diseases in this species. many adult cats are asymptomatic carriers. severe clinical signs are seen mostly in kittens or immunosuppressed adults. poor hygiene is a predisposing factor, and the disease may be endemic in shelters or catteries. humans may be easily infected and develop a similar skin disease. | 2013 | 23813824 |
| microsporum canis infection mimics pemphigus erythematosus. | we report a 55-year-old japanese woman with a two-month history of multiple pruritic erythema and erosion on her face and neck. based on the clinical appearance, we initially diagnosed her as having pemphigus erythematosus. however, the results of a histopathological examination and a direct immunofluorescence study did not support the initial diagnosis. additionally, anti-desmoglein 1 and 3 antibodies were all negative. subsequently, a microscopic examination of scales revealed filaments of fun ... | 2013 | 23723503 |
| preparation and in vivo evaluation of solid lipid nanoparticles of griseofulvin for dermal use. | griseofulvin-loaded solid lipid nanoparticles (slns) were prepared by hot microemulsion technique and optimized for type and concentration of lipid and surfactant. the optimized sln composition was characterized in terms of particle shape and size, drug entrapment efficiency, ph, stability, spreadability, ex-vivo skin permeation, dermatokinetics, skin sensitivity, in vitro antifungal assay and in vivo antifungal activity against microsporum canis using guinea pig model for dermatophytosis. the c ... | 2013 | 23621015 |