Publications

TitleAbstractYear(sorted ascending)
Filter
PMID
Filter
efficacy of griseofulvin and itraconazole in the treatment of experimentally induced dermatophytosis in cats.to evaluate the efficacy of itraconazole and griseofulvin in the treatment of microsporum canis infection, 15 juvenile cats were infected by topical application of 10(5) live m canis macroconidia to the skin of the lateral part of the trunk, and an occlusive bandage was applied. after 3 weeks, cats were randomly assigned to 1 of 3 treatment groups (n = 5 each): cats in the first group received griseofulvin (50 mg/kg of body weight, po, q 24 h); the second group received itraconazole (10 mg/kg, p ...19957591941
[changes in the fungal spectrum of dermatomycoses].the spectrum of aetiologic agents isolated from 3607 patients suspicious for dermatomycosis being in the care of the berlin charité clinics was analysed. identification of dermatophytes and moulds were performed conventionally. for the identification of yeasts biochemical and genetic methods were used. among the dermatophytes in comparison of present with previous incidence rates changes can be observed. opportunistic yeasts are recognized in increasing importance. five fungal species are formin ...19957630368
evaluation of topical therapies for the treatment of dermatophyte-infected hairs from dogs and cats.seven commonly used, topical antifungal products (i.e., lime sulfur, chlorhexidine, captan, povidone-iodine, sodium hypochlorite, and enilconazole solutions, and ketoconazole shampoo) were evaluated for their antifungal activity on microsporum canis-infected hairs from dogs and cats in an in vitro study. hairs were soaked or shampooed in each product for five minutes twice a week for four weeks. of the seven products used in this study, lime sulfur and enilconazole solutions were superior in inh ...19957634061
screening of hundred rwandese medicinal plants for antimicrobial and antiviral properties.a series of 100 rwandese medicinal plants (267 plant extracts), used by traditional healers to treat infections, were screened for antibacterial, antifungal and antiviral properties. the results of the testing showed that 45% were active against staphylococcus aureus, 2% against escherichia coli, 16% against pseudomonas aeruginosa, 7% against candida albicans, 80% against microsporum canis and 60% against trichophyton mentagrophytes. not less than 27% of the plant species exhibited prominent ant ...19957475121
the occurrence of dermatophytes in slovakia.we have compared the epidemiology of dermatophytoses in slovakia during the periods 1956-85 and 1986-92. infections caused by trichophyton rubrum gradually increased while infections due to trichophyton verrucosum and microsporum canis decreased.19957477094
anti-microbial activity and anti-complement activity of extracts obtained from selected hawaiian medicinal plants.selected plants having a history of use in polynesian traditional medicine for the treatment of infectious disease were investigated for anti-viral, anti-fungal and anti-bacterial activity in vitro. extracts from scaevola sericea, psychotria hawaiiensis, pipturus albidus and eugenia malaccensis showed selective anti-viral activity against herpes simplex virus-1 and 2 and vesicular stomatitis virus. aleurites moluccana extracts showed anti-bacterial activity against staphylococcus aureus and pseu ...19958786654
antidermatophytic activity of garlic (allium sativum) in vitro.interest in herbal medicine is enjoying a renaissance at present. garlic (allium sativum) is an intriguing herb with a long history of medicinal use for a variety of diseases including ringworm infections.19957790146
sertaconazole in the treatment of pediatric patients with cutaneous dermatophyte infections.sertaconazole is a new topical anti-mycotic with demonstrated efficacy against dermatophyte infections in adults. an open-label, multicenter study was conducted to assess the efficacy and tolerability of sertaconazole in children in primary care. twenty-nine children were initially included in the study and tolerability was assessed in all of them. the 16 children examined for efficacy (8 girls and 8 boys, aged 2 to 16 years) all had culture-confirmed cutaneous mycoses. fourteen children had tin ...19957614526
inability of two topical treatments to influence the course of experimentally induced dermatophytosis in cats.an experimental model of dermatophytosis was used to compare the efficacy of 2 topical antifungal treatments against microsporum canis infection in cats. infection was established in 24 cats by topical application of 10(5) m canis macroconidia to the skin of the lateral part of the abdomen under an occlusive bandage. three groups of 6 cats each then were treated twice weekly for 18 weeks with chlorhexidine shampoo and dip, detergent shampoo vehicle only, or glyceryl monolaurate shampoo. six cats ...19957601693
antimicrobial activity of cassia alata from malaysia.ethanolic extract of cassia alata leaves was investigated for its antimicrobial activities on several microorganisms including bacteria, yeast, dermatophytic fungi and non-dermatophytic fungi. in vitro, the extract exhibited high activity against various species of dermatophytic fungi but low activity against non-dermatophytic fungi. however, bacterial and yeast species showed resistance against in vitro treatment with the extract. the minimum inhibitory concentration (mic) values of the extract ...19957623478
antifungal activity of itraconazole and terbinafine in human stratum corneum: a comparative study.the evaluation of antifungal agents by in vitro and animal experiments cannot predict clinical efficacy with certainty. new models are needed to assess and compare antifungal activity.19957868711
fungal infections in the netherlands. prevailing fungi and pattern of infection.species of fungi have specific characteristics in geographic distribution, and they have a predilection for certain body areas.19957894094
dermatophytes from cases of skin disease in cats and dogs in turin, italy.in urban environments, pet animals such as dogs and cats may be largely responsible for the progressive increase of zoophilic over anthropophilic dermatophytes in the aetiology of human dermatophytoses. mapping, in each city, of the natural foci of zoophilic dermatophytes may thus be important for understanding the epidemiology of human dermatophytoses, and for planning preventive measures. we have surveyed dogs and cats suspected of carrying dermatophytic lesions in the turin area. hairs, skin ...19958531941
uv susceptibility and negative phototropism of dermatophytes.high doses of ultraviolet radiation (uvr) have well-known inhibitory effects upon dermatophytes. in the present study, the effect of repetitive low doses of uvr on mycelial growth of dermatophytes was tested. pellets of trichophyton rubrum, t. mentagrophytes and microsporum canis were placed between two thin layers of sabouraud glucose agar. obverse, reverse or both sides of these 'sandwich' agars were irradiated for 10 days twice daily with 0.13 or 0.17 j cm-2 uvb. to simulate microaerophilic c ...19958531931
dermatophytes in northern finland in 1982-90.the epidemiology of human dermatophytes was studied in northern finland in 1982-90. the samples were analysed at the department of medical microbiology, university of oulu. the total number of samples was 17,822, of which 3185 (18%) were positive. the annual number of samples and positive cultures remained relatively constant. trichophyton rubrum was the most common species being isolated from 2101 samples (66% of all positive cultures), while trichophyton mentagrophytes was isolated from 815 sa ...19958569818
production and use of monoclonal antibodies to microsporum canis.microsporum canis ncpf 179 and m. canis ncpf 177 dermatophyte cytoplasmic extracts (dces) were used as antigens to generate monoclonal antibodies (mabs). hybridomas with supernatants of optical density (od) > 1 for homologous dermatophyte cytoplasmic extracts (ce) and od < 0.5 for heterologous ce of candida albicans tested by the enzyme-linked immunosorbent assays (elisa) were selected for cloning. mabs secreted by cloned hybridoma lines were screened against ce of m. canis, m. gypseum, m. equin ...19958560740
in vitro antifungal activity of polyporaceae against yeasts and dermatophytes.the antifungal activity of 38 polyporaceae sensu lato against yeasts and dermatophytes was tested in vitro by the agar dilution method. strains were typed organisms and clinical isolates. in this first report, pycnoporellus fulgens (fr.) donk was found to be the most active species against pathological fungi and showed broad-spectrum antifungal activity against yeasts (candida albicans, candida glabrata) and dermatophytes (trichophyton mentagrophytes, trichophyton rubrum, microsporum canis, micr ...19958559195
extracellular enzymatic activity of microsporum canis isolates.the enzymatic activity of 70 feline and canine microsporum canis isolates was determined by the api-zym test. the liquid phase of cultures, inoculated into tryptic soy broth, was used to examine 19 enzymes. considerable differences were observed among the extracellular enzymatic patterns. all the isolates produced alkaline phosphatase and beta-glucosidase, while lipase (c14), trypsin, chymotrypsin, beta-glucuronidase, and alpha-fucosidase activity was never revealed. esterase (c4) activity was p ...19958684426
tinea capitis in the florence area between 1985 and 1993.this paper describes the main epidemiological findings in 203 patients with tinea capitis and in seven other patients with dermatophytosis that had also extended to the scalp. the patients were observed over a 9-year period (from 1985 to 1993) at the department of dermatology of the university of florence. tinea capitis was the fourth most frequent dermatophytosis. most of the patients were children, although 23 were adults. the most frequent aetiological agent was microsporum canis. it is inter ...19958559198
investigations of a killed dermatophyte cell-wall vaccine against infection with microsporum canis in cats.a laboratory-prepared killed microsporum canis cell-wall vaccine was evaluated under conditions simulating an accidental infection of a cattery, by inoculating eight- to nine-week-old cats with the vaccine or with a placebo control. the vaccinated cats developed high titres of anti-dermatophyte igg as measured by an elisa, and a small cell-mediated response against m canis as measured by a lymphocyte blastogenesis assay, using a whole fungus extract. after being inoculated the cats were challeng ...19958525097
preliminary screening of some squalenoid derivatives for toxicity towards dermatophytes.we report a preliminary study of the in vitro anti-dermatophyte activity of six squalenoid derivatives that inhibit 2,3-oxidosqualene cyclase and squalene epoxidase: 2-aza-2,3-dihydrosqualene, 22,23-epoxy-2-aza-2,3-dihydrosqualene, azasqualene alcohol, 19-aza-18,19,22,23-tetrahydrosqualene, 2,3-epoxy-19-aza-18,19,22,23-tetrahydrosqualene and hexafluorosqualene epoxide. the tests were done by inoculating 10 microliters of trichophyton mentagrophytes (robin) blanchard or microsporum canis bodin ho ...19958559196
tinea capitis in adults.invasion of keratin of the hair by dermatophytes is a rare event after puberty. a study of 2200 patients affected by various mycotic cutaneous infections during 6 years of observation brought to our attention three cases of tinea capitis in adults. confirming the studies of other authors, we also found that this disease mostly affected females. in all cases the isolated aetiological agent was microsporum canis, the fungus species most frequently responsible for tinea capitis in italy.19958559199
epidemiology of dermatophytoses observed in rome, italy, between 1985 and 1993.between 1985 and 1993, 13,880 patients were studied for possible forms of dermatophytoses. the most frequently isolated dermatophyte was in 2821 positive cases microsporum canis (50%), followed by trichophyton rubrum (27%), trichophyton mentagrophytes (10.6%), epidermophyton floccosum (9.3%), microsporum gypseum (2.3%), trichophyton violaceum (0.6%), trichophyton tonsurans (0.2%) and trichophyton verrucosum (< 0.1%). the genera and species isolated were also considered in relation to the site of ...19958569819
[microsporum canis as the origin of an enzootic outbreak in swine. a case report].we report on the outbreak of dermatomycosis caused by microsporum canis at a bavarian pig breeding and fattening farm. clinical signs were shown mainly by younger pigs. microsporum canis could be identified in skin scrapings of pigs, cats, and the farmer's daughter by culture and fluorescence microscopy. questions of epizootiology, diagnostics and therapy are discussed.19958585059
[microsporum canis tinea ciliaris and blepharitis].the involvement of eyelashes and eyelids by dermatophytes is unfrequent.19958729822
fungal contamination of the floors of swimming pools, particularly subtropical swimming paradises.we compared the level of dermatophyte contamination of the floors of traditional swimming pools and of subtropical swimming paradises, a new type of indoor swimming pool introduced in belgium in 1981. from the results of routine hygiene inspections over several years and of a comparative study, we can conclude that the floors of subtropical swimming pools are much more highly contaminated by dermatophytes than the floors of traditional swimming pools. this higher degree of contamination is due t ...19958720205
proximal subungual onychomycosis due to microsporum canis.a case of proximal subungual onychomycosis due to microsporum canis in a 36-year-old woman is presented. the onychomycosis involved the left thumb and the little fingernails, with thinning of the nail plate and crumbling of the nail plate surface. a milky-white discoloration of the proximal portion of the left thumbnail was also evident. a 2-mm longitudinal nail biopsy showed a large number of fungal elements in the whole length of the nail plate. fungal hyphae were more numerous in the ventral ...19968745910
a study of dermatophytoses in hamadan, the governmentship of west iran.in order to determine the extent and causative agents of dermatophytoses in the hamadan region of west iran; a study was made during a 9-month period from october 1991 to june 1992. a total of 7495 individuals were studied of whom 681 (9%) were suspect of having cutaneous mycoses. among them dermatophytoses were the commonest infections (259/681 = 38%). of 259 individuals infected with dermatophytes, tinea capitis were observed in 163 (62.9%); t. corporis in 27 (10.4%); t. manuum and t. cruris i ...19968751822
acquired immunity in experimental feline microsporum canis infection.seven adult cats were inoculated cutaneously at a shaved site with microsporum canis; five (group a) had spontaneously recovered from a previous m canis infection, and two (group b) were dermatophyte-naive. both of the dermatophyte-naive cats developed typical clinical disease, the lesions reaching maximal size four to five weeks after exposure, and resolving by week 13. only one of the group a cats developed clinical disease; the lesions were more inflammatory in nature and of shorter duration ...19968880989
isolation of fungi from the pelage of cats and dogs using the hairbrush technique.a total of 178 cats and 59 dogs in palmerston north, new zealand were sampled for the presence of keratinophilic fungi on their pelage; 57.8% had fungi. the fungi were classified in 20 genera with the predominant species being members of the genera; chrysosporium, microsporum and trichophyton. cats were the major carriers of keratinolytic fungi. 18.5% of the cats and 5.1% of the dogs were either carriers or infected with m. canis. microsporum canis was a frequent isolate and its distribution had ...19968981779
diagnostic results in animal dermatophytoses.superficial mycoses caused by dermatophytes, as well as asymptomatic carriership of dermatophytes, have a high prevalence among domestic animals and pets. we examined 606 clinical specimens from skin lesions of animals with a significant tendency towards superficial mycosis due to their clinical features. samples were obtained from horses, dogs, cats, small rodents, birds, and rabbits. the specimens were examined by microscopic and cultural techniques. microscopically, there was no significant d ...19968976618
subcutaneous mycosis in a cat due to staphylotrichum coccosporum.a 5.5-year-old, male, feline leucosis virus-positive cat developed a concurrent dermatophytosis due to microsporum canis and a subcutaneous infection due to staphylotrichum coccosporum. st. coccosporum caused mycetoma-like lesions. the fungal elements revealed features like those seen in phaeohyphomycosis. until now st. coccosporum has been described to be non-pathogenic. the pathogenicity of st. coccosporum was corroborated by experimental infection.19969009663
human androgenic steroids affect growth of dermatophytes in vitro.hormonal effects on fungal growth are of particular interest to medical mycology. in the skin, androgenic steroids metabolized within pilosebaceous units may have direct effects on dermatophytes that invade hair follicles. in this study, 10(-1) to 10(2) mg 1(-1) testosterone, 5-alpha-dihydrotestosterone, dehydroepiandrosterone, androstenedione and androstanedione were used in agar dilution assays to test their effects on thallus diameters of trichophyton rubrum, epidermophyton floccosum, t. tons ...19969009664
fungal flora of the hair coat of stray cats in iran.the fungal flora of the hair coat of 100 stray cats in different districts of the city of isfahan, iran, were examined. saprophytic fungi were isolated from all cats. penicillium, aspergillus, alternaria, mucor and cladosporium spp. were the most frequently isolated saprophytes. microsporum canis was isolated from all kittens with clinical signs of dermatophytosis. in other cases, m. canis was isolated only from 22 of the 96 cats. no significant differences in sex, hair length, and fungal flora ...19968909038
tinea capitis in adults.between 1973 and 1994, 17 cases of tinea capitis in adults were observed in the dermatology clinic of the university of cagliari (italy). the patients were all women (age range 17-76 years) and came from the district of cagliari. at the time of referral, they presented with a disease duration varying from 8 to 10 months. the main clinical feature was scalp lesions, but in two cases mycotic lesions on the face were also present. the following dermatophytes were isolated: microsporum canis (eight ...19969009649
psoriasiform id reaction in tinea corporis.a case of tinea corporis due to microsporum canis followed by a scattered psoriasiform eruption is reported. the nature, clinical features and pathogenesis of the dermatophytid are discussed.19969009651
[fungi and yeasts isolated in mycological studies in skin and nail infections in the netherlands, 1992-1993].to describe fungi and yeasts isolated from skin and nail infections in the netherlands.19968684495
isolation of keratinophilic fungi from the floors of private veterinary clinics in italy.to evaluate the presence of keratinophilic fungi in the environment, 400 samples were collected from the floors of 50 private veterinary clinics using 55-mm-diameter 'contact plates', containing mycobiotic agar. after incubation for 15 days at 25 degrees c, the following species were isolated: microsporum canis, trichophyton terrestre, chrysosporium keratinophilum, chrysosporium sp., microsporum gypseum, trichophyton ajelloi, chrysosporium tropicum, trichophyton mentagrophytes, chrysosporium sta ...19968711896
microsporum canis infections in children: results of a new oral antifungal therapy.clinical and laboratory data from 22 children with tinea corporis and tinea capitis caused by microsporum canis (10 tinea corporis, 12 tinea capitis), confirmed by microscopic examination and culture and partly pretreated with griseofulvin or terbinafine, are summarized. the children were treated consecutively with itraconazole in our clinic during 1994/95. the age of the children ranged between 4 and 13 years, with girls being affected much more frequently than boys. oral, individually adapted, ...19969009643
unusual microsporum canis infections in adult hiv patients.tinea capitis in men, even if infected with hiv, is infrequent. microsporum species nail infections are extremely rare. in most cases microsporum canis infection is usually easy to treat with antifungal agents. we describe two hiv-infected men with an unusual m. canis infection. both patients had tinea capitis, presenting as alopecia in one and scaling of the scalp in the other. one patient also had tinea unguium caused by m. canis. ketoconazole was ineffective in both patients; terbinafine was ...19968912591
partial characterization of proteolytic enzymes of microsporum canis and microsporum cookei.characterization by proteinase inhibitors of the enzymes produced by microsporum spp. revealed that microsporum canis and microsporum cookei produce serine proteinase(s), but only m. canis expresses aspartic and cysteine proteinases and probably a metalloproteinase. both m. canis and m. cookei expressed metalloelastinolytic proteinases. all the proteinase types have been implicated in the pathogenicity of a wide range of microorganisms.19969009645
effect of glucose and thiamine concentrations on the formation of macroconidia in dermatophytes. occurrence of dysgonic microsporum canis strains in athens, greece.data collected from multiple trials with 110 fresh and preserved clinical isolates of trichophyton mentagrophytes var. mentagrophytes, t. violaceum, t. rubrum, t. verrucosum, microsporum canis and epidermophyton floccosum revealed that production of macroconidia depends on glucose and thiamine concentrations in the medium. optimal macroconidia production was obtained at the critical concentrations of 5 g l-1 glucose and 0.6 g l-1 thiamine when the two compounds were used in combination. the same ...19968786761
primary invasive cutaneous microsporum canis infections in immunocompromised patients.two cases of primary invasive cutaneous infections caused by the zoophilic dermatophytic species microsporum canis are presented. the first case occurred in a liver transplant recipient who was receiving immunosuppressive therapy. multiple erythematous papules were seen on both legs, and a biopsy revealed invasive fungal hyphae. the second case was diagnosed in a human immunodeficiency virus-positive individual with a cd4 lymphocyte count of 81 mm3. raised red nodules were seen on her scalp and ...19968789040
itraconazole responsive tinea capitis in an hiv-infected child.tinea capitis has not been reported to be a prevalent or serious affliction in pediatric patients infected with the human immunodeficiency virus (hiv). we report tinea capitis due to microsporum canis in a boy infected with hiv. after failing conventional therapy, he was treated successfully with a four-week course of itraconazole. his immunologic status improved during therapy. the possible relationship of this response to the ultimate resolution of disease is discussed.19968844753
fungi responsible for skin mycoses in turin (italy).there has been a recent increase in the frequency of skin mycoses, coupled with changes in the epidemiology and distribution of the species responsible. periodic epidemiological analyses of these disease are thus required to ensure their efficacious control. hair fragments, skin scrapings, specimens from vesicles and blisters and nail parings were seeded on petri dishes loaded with sabouraud or mycosel agar, supplemented with chloramphenicol and with chloramphenicol plus cycloheximide respective ...19968767009
in vitro susceptibility of fungi to acyclic inhibitors of 2,3-oxidosqualene cyclases.in the present study we determine the antifungal properties of two acyclic inhibitors of 2,3-oxidosqualene cyclases: 22,23-epoxy-2-aza-2,3-dihydrosqualene (eas) and azasqualene alcohol (asa). fungistatic and fungicidal activity towards dermatophytes and other fungi involved in cutaneous and systemic infections was tested (48 isolates from 10 species). the tests were carried out by inoculating 10 microliters of mycelial homogenate in 1 ml of sabouraud glucose liquid medium containing serial dilut ...19968786759
tinea corporis bullosa anularis.a case of annular bullous tinea corporis (tinea corporis bullosa anularis) in a 27-year-old woman is reported. the infection was characterized by numerous lesions localized exclusively to the forearms and the legs. these lesions were erythematous and scaling with bullous and annular borders. mycological culture yielded microsporum canis.19968864372
[scanning electron microscope sudy of the morphology of fungi isolated from patients at the aristide la dantec hospital in dakar, senegal].in order to improve the identification of fungi usually isolated among some patients at dantec hospital, a study by scanning electron microscopy has been carried out. it deals with four species of yeasts (candida albicans, candida parapsilosis, rhodotorula rubra sacharomyces cerevisiae) six species of dermatophytes (trichophyton rubrum, trichophyton soudanense, trichophyton interdigitale, microsporum canis, trichophyton violaceum, microsporum audouinii); two species of mildew, (aspergullus flavu ...19969827085
dermatophytoses in the gdańsk area, poland: a 12-year survey.a survey of dermatophytes and dermatophytoses was carried out among patients of the department of dermatology, medical university of gdańsk, in the years 1984-95. over the 12-year period, 1195 cases of ringworm were seen: 55% in men and 45% in women. listing the dermatophytes isolated and their frequencies as a percentage of the total are as follows: trichophyton mentagrophytes 42.1%, microsporum canis 26.0%, trichophyton rubrum 14.7%, epidermophyton floccosum 11.0%, trichophyton tonsurans 4.6%, ...19969009667
contact-sensing by hyphae of dermatophytic and saprophytic fungi.contact-sensing or thigmotropism is the directional growth response of cells in relation to topographical guidance cues. thigmotropism is thought to play a major role in the location of infectable sites on plants by phytopathogenic fungi and has recently been shown to be a property of hyphae in the human pathogenic fungus candida albicans. here we show that hyphae of the dermatophytes epidermophyton floccosum, microsporum canis and trichophyton mentagrophytes reorientate their direction of growt ...19979292428
some aspects of dermatophytoses seen at university hospital in florianópolis, santa catarina, brazil.dematophytoses comprise mycoses which are very frequently diagnosed in the routine of clinical laboratories of florianópolis, like any other brazilian cities. however, no clinical or epidemiological studies data have been published for that city so far. to partially clarify these questions, we carried out a study on this subject on patients who sought the mycology services of hospital of federal university of santa catarina, from january 1995 to november 1996. the most prevalent dermatophyte was ...19979460252
dermatophytomycoses in children in rural kenya: the impact of primary health care.in a survey of 5780 children from 13 schools in rural kisumu district (western kenya) in 1993, a prevalence rate of dermatophytomycoses of 10.1% was found. three-quarters of the affected children suffered from tinea capitis (prevalence rate 7.8%), caused by microsporum audouinii var. langeronii, trichophyton violaceum and microsporum canis. in 1994, a dermatology programme within the primary health care system was started. twelve community health workers (chws), trained in diagnosis and treatmen ...19979260482
the use of oral terbinafine (lamisil) in children.in an ongoing study of lamisil in children, 21 patients have so far been enrolled and preliminary data are reported in this paper. eighteen have tinea capitis and 1 has tinea corporis. so far, trichophyton tonsurans has been identified in 17 and trichophyton violaceum in 2. lamisil has so far proved to be well tolerated, efficacious and cost-effective in a 2-week course in those children with a trichophyton species. if microsporum canis is isolated, a longer course is probably indicated. lamisil ...19979154402
[microsporum infections in hajdú-bihar county].mycotic infections caused by microsporum canis occurred in 237 cases between 1983-1995 in hajdú-bihar county. the disease accumulated seasonally up during the beginning of summer and the end of autumn, in particularly. children and young people had often got microsporiasis. women patients seemed to be more frequent than men. the disease in many cases, appeared on all members of families. a main factor in spreading of pathogen were apparently healthy persian cats. only few cases could be observed ...19979254352
prevalence and characterization of microsporum canis carriage in cats.in order to determine the prevalence and to characterize the carriage of microsporum canis in cats, different mycological examinations (including a culture obtained by hair brushing and wood's light examination) were performed on 632 animals of different origins. group 1 comprised 467 healthy pet cats belonging to veterinary students. in this group, prevalence of carriage was 2.1%: eight cats were asymptomatic transient carriers and one cat was an asymptomatic infected animal presenting discrete ...19979292421
systemic antifungal treatment of children with terbinafine.at present, griseofulvin is the only licensed drug for oral treatment of dermatophyte infections in children.19979310719
dermatophytes isolated from domestic animals in barcelona, spain.this retrospective study deals with the main samples studied at the mycology diagnostic service of the faculty of veterinary science of barcelona: animals with suspected dermatophytosis. over a ten-year period from 1986 to 1995, 136 dermatophytes were identified from dog and cat cultures submitted for identification and from specimens submitted for mycological examination from a variety of other domestic animals. the most frequent dermatophytes isolated were microsporum canis (55.9%), trichophyt ...19979335154
povidone-iodine wash solutions in the prevention of superficial fungal infections; predictive evaluation using the corneofungimetry bioassay.prevention of superficial mycoses remains a stubborn problem. the effect of antiseptics for that purpose is largely unknown. we studied the potential fungitoxic activity of povidone iodine (pvp-i) contained in wash solutions.19979403279
a succinylanthranilic acid ester and other bioactive constituents of jolyna laminarioides.methyl 2-[propanamide-2'-methoxycarbonyl] benzoate, fucosterol, trans-phytol and p-formylphenol were isolated for the first time from a methanolic extract of jolyna laminarioides. methyl 2-[propanamide-2'-methoxycarbonyl]-benzoate exhibited chymotrypsin inhibitory activity and also found to be active against escherichia coli and shigella boydii. fucosterol exhibited antifungal activity against curvularia lunata, stachybotrys atra and microsporum canis.19979423291
tinea capitis in children in the district of cagliari, italy.between 1986 and 1995, 4104 children were observed in the clinic of dermatology in cagliari, italy. three hundred and thirty-six children (8.2%), 188 boys and 148 girls, aged 1 month to 13 years, were affected by tinea capitis. microsporum canis was detected in 278 cases (82.7%) and trichophyton mentagrophytes in 58 cases (17.3%). systemic treatment with 20-25 mg kg-1 day-1 griseofulvin led to complete recovery in 30-40 days. none of the patients relapsed. the epidemiology of the infection was a ...19979476495
[mycetomas caused by microsporum canis. report of one case].we report an eight years old boy presenting with a pyogenic granuloma of the scalp, generalized alopecia, descamative plates in the neck, trunk and limbs and nail involvement. cultures for fungus of all these lesions disclosed microspore canis. the patient was treated with oral griseofulvin, miconazole and topical tolnaftate. five years later and after several incomplete treatments, the patient returns with a fistulous mass of 15 x 8 cm in the dorsal area whose culture revealed microspore canis. ...19979567397
in vitro evaluation of antifungal properties of 8.o.4'-neolignans.eighteen racemic 8.o.4'-neolignans with six different substitution patterns in rings a and b, in their ketone and in their erythro and threo alcoholic forms, were evaluated for antifungal activity by the agar dilution method. only the alcohols exhibited a broad spectrum of activities against microsporum canis, microsporum gypseum, tricophyton mentagrophytes, tricophyton rubrum, and epidermophyton floccosum. (+/-)-erythro-3,4-(methylenedioxy) -7-hydroxy-1'-allyl-3',5'-dimethoxy-8.o.4'-neolignan ( ...19979249968
itraconazole susceptibility of feline isolates of microsporum canis.the in vitro activity of itraconazole against microsporum canis was evaluated with 38 feline isolates. based on the observed minimum inhibitory concentrations it can be concluded that the drug could be effective in the therapy of cats affected by m. canis ringworm.19979476516
prevalence and aetiology of dermatophytoses in isfahan, iran.in this study the prevalence and causative agents of dermatophytoses in isfahan, a large province of iran, were determined. of 16,578 clinically suspected cases 13.3% were affected with dermatophytoses. lesions of tinea capitis were the most prevalent clinical type of dermatophytoses (54.1%), followed by tinea corporis (23.8%) and tinea pedis (8.9%). trichophyton verrucosum was the most frequent causative agent (32.8%), followed by epidermophyton floccosum (17.6%), t. mentagrophytes (16.2%) and ...19979476518
[dermatophytes isolated in our clinics. 5-year-study in zaragoza].this review summarizes the different species of dermatophytes isolates in our laboratory between 1991 and 1995. we describe the clinical forms and establish the distribution over this period of time.19979580210
microsporum canis infection of the penis. 19979582492
prevalence of undetected tinea capitis in a school survey in spain.from october 1994 to november 1995, a prospective study aiming to detect dermatophytes on the scalp was undertaken in 5000 unselected school children aged between 3 and 16 years (mean age 8.34 years, sd +/- 3.83). thirty-two (0.64%) had dermatophytes in the scalp, 22. (0.44%) had tinea capitis and 10 were asymptomatic scalp carriers. it is important to point out that 33% of the patients with tinea capitis and 60% of the asymptomatic scalp carriers also had ringworm in other body sites. there was ...19979375502
lack of efficacy of 6-week treatment with oral terbinafine for tinea capitis due to microsporum canis in children.twenty-two children aged 2 to 9 years with noninflammatory tinea capitis due to microsporum canis were evaluated in an open clinical pilot study run from january 1994 to july 1995. each child was given oral terbinafine according to body weight for 6 weeks. mycologic evaluation was done at the end of treatment and after follow-up periods of 4 and 8 weeks. none of the patients achieved complete mycologic cure by the end of the treatment period. four weeks later complete mycologic cure was establis ...19979050765
wood's light in microsporum canis positive patients.in 64 patients with culturally proven microsporum canis infections, wood's light examination was performed. in 30 patients (47%) the characteristic fluorescence correlated with the cultural findings, whereas in the remaining 34 patients (53%), microsporum canis was isolated, although wood's light examination was negative. of the 30 positive and 34 negative cases eight patients of each group had been pre-treated. from the results presented, wood's light examination has a poor sensitivity in cases ...19979470413
dermatophytes isolated from asymptomatic stray cats.most human cases of dermatophytosis diagnosed in siena, italy, in the last 5 years have been caused by two zoophilic species: microsporum canis and trichophyton mentagrophytes. since many patients had a history of contact with apparently healthy stray cats, we examined the fur of 173 stray cats for dermatophytes. the cats were captured in different parts of siena and none of them had mycotic lesions. microsporum canis was isolated in 82 cats, trichophyton mentagrophytes in three and microsporum ...19979470415
[etiologic and epidemiologic study of dermatomycoses in navarra (spain)].we review the etiology of the dermatophytosis in navarra (spain) over a 5-year period and it is compared with previous studies. we have isolated 312 strains of dermatophyte fungi in 285 patients (188 men and 97 women). trichophyton rubrum was the most frequently isolated species (58.6%) followed by trichophyton mentagrophytes (26.2%) and microsporum canis (10.5%). concerning the location of the lesions, tinea pedis was the clinical pattern found in the greatest number of patients, followed by ti ...199716854174
[enzymatic activities of microsporum canis and microsporum gypseum strains.].the presence of 11 enzymatic activities, detected by qualitative methods, and 19 enzymes, semi-quantitatively detected by api zym system, in strains belonging to microsporum canis and microsporum gypseum has been studied. no pronounced differences were noted between microsporum canis and microsporum gypseum, although microsporum gypseum presented in some cases more intense enzymatic activities than microsporum canis.199717655387
[terbinafine and microsporum canis tinea capitis.]. 199817655409
butenafine.butenafine is a new antifungal agent with primary fungicidal activity against dermatophytes such as trichophyton mentagrophytes, microsporum canis and trichophyton rubrum which cause tinea infections. 14c-labelled butenafine (approximately 30 micrograms/g tissue) was found within guinea-pig dorsal skin 24 hours after topical application. most of the drug was distributed into the epidermis including the horny layer. small amounts were found in the dermis, probably transported via sebaceous glands ...19989530545
a survey of dermatophytes isolated from human patients in the united states from 1993 to 1995.a survey of dermatophytes, isolated from human patients seeking medical attention, was conducted for the years 1993 to 1995. data were collected from 23 states throughout the continental united states and the district of columbia and from 44 to 45 laboratories. these data were compared with the results of two earlier surveys (1979 to 1981 and 1985 to 1987). in contrast to the earlier surveys trichophyton tonsurans became the most frequently isolated dermatophyte (44.9%) followed by t. rubrum (41 ...19989704838
[dermatomycosis caused by trichophyton verrucosum in mother and child].in recent years, there has been an epidemiological renaissance of zoophilic dermatophytoses caused by a variety of factors. at present, the most important causative organisms are microsporum canis, trichophyton mentagrophytes var. granulosum and, as in the present case, trichophyton verrucosum. these are formerly notifiable pathogens which are highly virulent and contagious. the example of an extensive, originally unrecognized tinea corporis et faciei in mother and child presented here shows the ...19989715387
identification of clinical isolates of microsporum canis and m. gypseum by random amplification of polymorphic dna (rapd) and southern hybridization analyses.clinical isolates of microsporum canis and m. gypseum from humans, dogs and cats were examined by random amplification of polymorphic dna (rapd) and southern hybridization analyses. the rapd band patterns of six clinical isolates of m. canis were identical to those of standard strains of arthroderma otae. of nine clinical isolates of m. gypseum seven and two isolates showed rapd patterns identical to those of standard strains of a. gypseum and a. incurvatum respectively. southern blot analysis u ...19989670766
isozyme variation within and among populations of microsporum species.isozyme variation among 54 isolates of microsporum canis, 18 microsporum cookei isolates and two diheterospora isolates were studied using starch gel electrophoresis. of eight enzymes examined, four were polymorphic (est, g6p, mdh and pep), having from two to four electrophoretic forms. within each species, consistent and reproducible isozyme patterns of the eight enzyme systems were obtained. phenotypic diversity (h) in m. canis was higher than in m. cookei (h = 0.459 and h = 0.408 respectively ...19989919894
antimicrobial effects of aqueous plant extracts on the fungi microsporum canis and trichophyton rubrum and on three bacterial species.aqueous extracts of 10 plants were tested for their ability to inhibit trichophyton rubrum and microsporum canis, the aetiological agents of dermal fungal infections in humans. these extracts were also evaluated for their activity against some bacteria. aqueous extracts from the leaves of inula viscosa produced detectable antifungal activity against these dermatophytes.19989489036
griseofulvin and terbinafine in the treatment of tinea capitis in children.to compare the effectiveness of griseofulvin and terbinafine in the treatment of tinea capitis in children.19989539918
[two cases of tinea capitis with different clinical courses].we report cases of two 4-year-old boys with tinea capitis who attend the same daynursery. clinically, on the first visit both lesions were a superficial type, however we initiated treatment with a dose of 50 mg/day of oral itraconazole. althougth the lesion of case 2 improved after 11 weeks of treatment, case 1 developed to kerion celsi and required continued treatment for 22 weeks for cure. microsporum canis was isolated from the hairs of both cases and mic of itraconazole against both isolates ...19989580037
relapsing tinea capitis by microsporum canis in an adult female renal transplant recipient.scalp ringworm is very uncommon in adults. the occurrence and the atypical clinical course of this unusual dermatophytosis in a female renal transplant recipient are described. furthermore, the prevalence and the clinical features of superficial fungal infection in renal transplant recipients are reviewed. as immunosuppression enhances the risk of antifungal therapy failure, more prolonged treatment and careful follow-up are necessary to obtain complete recovery from any dermatophytosis in renal ...19989730705
fungal flora in human skin and skin appendages infections in the region of lódź, poland.in the years 1987-95, 3550 patients with mycotic skin infections were divided into two groups: a group of 2282 (64.3%) subjects with dermatophytosis and a group of 1268 (35.7%) subjects with other fungal infections. among dermatophytes the most common infectious agent was trichophyton mentagrophytes (33%), followed by t. rubrum (30%) and microsporum canis (11%). a total of 17% of all infections were caused by candida sp.19989715642
kerion celsi: a clinical epidemiological study.we present a case record of patients with kerion celsi observed in the clinic of dermatology, university of cagliari (italy) from 1981 to 1995. altogether, 31 children (18 male and 13 female) with an age range of 40 days to 12 years were studied. in all cases the lesions were confined to the scalp. in 10 cases the disease developed as such, while in 21 patients it represented the inflammatory evolution of tinea capitis secondary to incongruous topical treatment. microsporum canis was isolated in ...19989670770
differentiation of microsporum species by random amplification of polymorphic dna (rapd) and southern hybridization analyses.molecular characterization of 18 species belonging to the genus microsporum isolated from human and animal dermatophytosis was carried out by random amplification of polymorphic dna (rapd) and southern hybridization analyses. all of these 18 microsporum species showed different band patterns specific to each species in rapd analysis. southern hybridization analysis using c3 probe derived from a rapd band from arthroderma otae, teleomorph of m. canis, revealed distinct bands in 14 of the 18 micro ...19989715638
epidemiological study of tinea capitis in schoolchildren in the nablus area (west bank).a study of tinea capitis was carried out during the period january-june 1996 in 7525 primary schoolchildren aged 6-14 years comprising 4050 boys and 3475 girls in the nablus district in the palestinian area. fourteen primary schools located in rural, urban and refugee camp areas were surveyed in this study. seventy-five (1.0%) mycologically proven cases of tinea capitis were detected. the incidence was higher in schools in rural areas (1.9%) than in refugee camps (1.1%) or urban areas (0.4%). al ...19989715641
[dermatophytosis in the greater resistencia area, chaco province, argentina].epidemiological characteristics of dermatophytoses in the metropolitan area of resistencia city are described. hair fragments, skin, scalp or nail scrapings were collected from 3.507 persons with dermatological symptoms of probable fungal origin. the mycological studies were performed by three mycological laboratories, one from a university institute and two from private laboratories. direct microscopic examinations showed fungi in 39.66% of samples, while the recovering of dermatophytes from cu ...19989744034
itraconazole oral solution for the treatment of tinea capitis.twenty-seven children (12 boys, 15 girls, age range 3-11 years, weight range 10-40 kg) were treated with itraconazole oral solution 10 mg/ml given as pulse therapy for tinea capitis. the dosage regimen was 3 mg/kg per day given once daily in a fasting state with each pulse lasting 1 week. the first two pulses were separated by a 2-week off-drug period, and the second and third pulses had a 3-week period without drug between them. for each patient a second and third pulse were administered if the ...19989764158
increased incidence of trichophyton tonsurans tinea capitis in ontario, canada between 1985 and 1996.in canada, since the 1990s, trichophyton tonsurans has emerged as the main cause of tinea capitis. prior to this the more common agents were t. verrucosum, microsporum canis and m. audouinii. over the past few years the incidence of t. tonsurans has increased such that in 1985 and 1996 the cases of mycologically confirmed tinea capitis due to t. tonsurans were 9% and 76%, respectively. the epidemic of t. tonsurans has reduced the role of wood's lamp in diagnosis of tinea capitis. the age distrib ...19989776814
comments on microsporum canis. 19989776843
purification and characterization of a 315 kda keratinolytic subtilisin-like serine protease from microsporum canis and evidence of its secretion in naturally infected cats.a keratinolytic protease, secreted as the major component by a feline clinical isolate of microsporum canis cultivated in a minimal medium containing cat keratin, was purified by affinity chromatography on bacitracin agarose and gel filtration. the apparent molecular mass of the enzyme was 31.5 kda and the pi was 11.8. the enzyme was not glycosylated and its first 15 n-terminal amino acids showed numerous similarities with other fungal subtilisins. the optimum ph was around 9 while inactivation ...199810206750
terbinafine (lamisil) therapy for microsporum canis scalp ringworm. 19989861751
tinea capitis dermatophytes: susceptibility to antifungal drugs tested in vitro and in vivo.tinea capitis is a worldwide-spread infection of the scalp caused by dermatophytes and is predominantly seen in children. the clinical manifestations range from mild scaling lesions to widespread alopecia or highly inflammatory suppurating lesions. terbinafine and itraconazole seem to be promising therapies with shorter treatment durations than griseofulvin.19989873175
parasitic relationship between microsporum canis and the cat.cats are often cited as reservoirs of m. canis but it is questionable whether m. canis is part of the resident flora of the cat's skin and hair or only a transient organism. studies indicate that m. canis is most often isolated from cats at risk of infection or exposure from other infected cats or from a contaminated environment. many more cats are culture-positive for m. canis than have dermatophytosis. culture isolation alone is not an indication of dermatophytosis; the diagnosis of dermatophy ...19989988517
prevalence of undetected tinea capitis in a prospective school survey in madrid: emergence of new causative fungi.from october 1994 to december 1996, a prospective study was undertaken in 10,000 unselected school children in madrid, aged between 2 and 16 years (mean +/- sd 8.5 +/- 3.6 years). fifty-two (0.52%) (including 13 immigrants from africa) had dermatophytes in the scalp: 33 (0.33%) (including 10 immigrants from africa) had tinea capitis and 19 were scalp carriers. almost half of the symptomatic cases were caused by trichophyton tonsurans (12 of 33 cases) and microsporum canis (16 of 33 cases). t. to ...19989640375
[zoophilic dermatophytes as epizoonoses pathogens and their significance to dermatology].different dermatophytes occurring primarily in animals may be transmissible to man and produce human disease; such zoophilic fungi should be considered a possible cause of skin lesions of unclear origin. several species including trichophyton verrucosum, trichophyton mentagrophytes and microsporum canis may infect human skin, causing a variety of signs and symptoms. people who have close contact to infested cattle or cats are more often exposed to fungal infections. certain professions, such as ...19989675572
the in vitro and in vivo production of a 31.5-kd keratinolytic subtilase from microsporum canis and the clinical status in naturally infected cats.microsporum-canis-infected cats, especially the asymptomatic infected ones, are mainly responsible for the zoonotic disease. the important variability of the clinical signs in cats is poorly understood. recently, a 31.5-kd keratinolytic subtilase was found to be a putative virulence factor.19989669125
efficacy of oral administration of itraconazole to cats with dermatophytosis caused by microsporum canis.to determine efficacy of orally administered itraconazole in cats with dermatophytosis caused by microsporum canis.19989776995
isozyme variation of microsporum canis and m. cookei from new zealand.fifty-four isolates of microsporum canis (arthroderma otae) from humans, cats and dogs obtained from auckland, palmerston north and wellington, new zealand and 18 m. cookei and two diheterospori spp. from soils were examined for variation using eight isozyme loci. m. canis isolates were from infected and non-infected cases. isozyme analysis separated the three species which were further subdivided into electrophoretic types (ets). clustering analysis using normalized percentage disagreement (ptc ...199810075493
antifungal activity of plant extracts against dermatophytes.the aqueous extracts (15 micrograms ml-1 medium) of 22 plants used in folkloric medicine in palestine were investigated for their antifungal activity and minimum inhibitory concentrations (mics) against nine isolates of microsporum canis, trichophyton mentagrophytes and trichophyton violaceum. the extract of the different plant species reduced colony growth of the three dermatophytes by 36 to 100% compared with the control treatment. antimycotic activity of the extract against the three dermatop ...199910680445
Refresh
firstprev
12345678910...
nextlast
Displaying items 401 - 500 of 1282