Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| isolation, identification, and in vitro antifungal susceptibility testing of dermatophytes from clinical samples at sohag university hospital in egypt. | the objective of this study was to isolate, identify, and explore the in-vitro antifungal susceptibility pattern of dermatophytes isolated from clinically suspected cases of dermatophytosis (tinea infections) attending the dermatology outpatient clinic. | 2016 | 27504173 |
| melokhanines a-j, bioactive monoterpenoid indole alkaloids with diverse skeletons from melodinus khasianus. | the new melokhanines a-j (1-10) and 22 known (11-32) alkaloids were isolated from the twigs and leaves of melodinus khasianus. the new compounds and their absolute configurations were elucidated by extensive analysis of spectroscopic, x-ray diffraction, and computational data. melokhanine a (1), composed of a hydroxyindolinone linked to an octahydrofuro[2,3-b]pyridine moiety, is an unprecedented monoterpenoid indole alkaloid. melokhanines b-h (2-8) possess a new 6/5/5/6/6 pentacyclic indole alka ... | 2016 | 27584856 |
| [evolution of tinea capitis observed in mycology laboratory of institute pasteur of algeria from1995 to 2015]. | tinea capitis are common in algeria and are a frequent reason for consultation. this mycosis affects children and rarely adults. this is a retrospective study over a period of 20 years from 1995 to 2015 at the mycology laboratory of the pasteur institute of algeria. | 2016 | 27554867 |
| diagnostic performance of molecular and conventional methods for identification of dermatophyte species from clinically infected arabian horses in egypt. | rapid and accurate identification of dermatophytes is crucial for the effective control of disease outbreaks. current methods based on culture and microscopic characteristics may require weeks before positive identification is made. | 2016 | 27549079 |
| [tinea capitis in the military hospital avicenna (morocco): review of 8 years (2006-2013)]. | tinea capitis are due to fungal infection by dermatophytes. they are common in developing countries including morocco. the objective of this study intended to describe the epidemiology, clinical and mycological profile of tinea capitis in avicenna military hospital of marrakech. | 2016 | 26778722 |
| overexpression of tlr-2 and tlr-4 mrna in feline polymorphonuclear neutrophils exposed to microsporum canis. | polymorphonuclear neutrophils (pmns), along with macrophages, are the first leukocytes recruited to the site of infection in dermatophytoses and are responsible for the in fine elimination of the fungus. it has been demonstrated that feline pmns produce pro-inflammatory cytokines after stimulation with microsporum canis. the activation of these cells results from the recognition of specific pamps (pathogen associated molecular patterns) from m. canis by prrs (pattern recognition receptors) of pm ... | 2016 | 26914839 |
| detection of dermatophytes in healthy companion dogs and cats in eastern india. | in recent times increasing occurrence of dermatophytosis, especially among the school children in eastern india was evidenced along with increased tendency of keeping companion animals such as dogs and cats. this study was undertaken to detect the occurrence of dermatophytes with antifungal susceptibility among the companion animals. a total of 1501 healthy companion animals comprising 1209 dogs and 292 cats belonged to individual owners in and around kolkata (west bengal, india) were examined f ... | 2016 | 27656224 |
| pcr and real-time pcr approaches to the identification of arthroderma otae species microsporum canis and microsporum audouinii/microsporum ferrugineum. | the identification of species in the arthroderma otae complex is essential to determine the origin of infection and to eliminate the risk of transmission. microsporum canis is a zoophilic species, whereas microsporum audouinii and microsporum ferrugineum are anthropophilic species. in this paper, we propose alternative methods that permit species-specific identification of both anthropophilic and zoophilic members of the a. otae complex methods: two pcr assays were designed based on differences ... | 2016 | 27306227 |
| tinea capitis: temporal shift in pathogens and epidemiology. | tinea capitis is the most common type of dermatomycosis in children. its pathogen profile shows geographic variations as well as temporal shifts. | 2016 | 27509419 |
| tinea on a tattoo. | in the last twenty years, the prevalence of individuals with tattoos in the general population has increased in europe (1) as well as in australia (2) and the united states of america (3). a series of complications such as acute inflammatory reactions, allergic contact dermatitis (4,5), photoinduced, lichenoid, and granulomatous reactions (6, 7), pseudolymphoma (8), pseudoepitheliomatous hyperplasia (9), skin infections (6), and skin cancers (10) may occur on tattoos. infectious complications on ... | 2016 | 27663926 |
| species identification of dermatophytes in paraffin-embedded biopsies with a new polymerase chain reaction assay targeting the internal transcribed spacer 2 region and comparison with histopathological features. | dermatophytosis is a very common skin infection with a broad clinical spectrum. biopsies are often used to confirm the diagnosis, especially when the clinical presentation is unusual. not uncommonly, organisms are hard to find even with periodic acid-schiff stains. polymerase chain reaction (pcr) for dermatophytes can be used in such cases. | 2016 | 26556042 |
| efficacy of topical therapy with newly developed terbinafine and econazole formulations in the treatment of dermatophytosis in cats. | in the field of veterinary dermatology dermatophytosis is one of the most frequently occurring infectious diseases, therefore its treatment should be effective, convenient, safe and inexpensive. the aim of this study was to evaluate the efficacy of newly developed topical formulations in the treatment of cats with dermatophytosis. evaluation of clinical efficacy and safety of terbinafine and econazole formulations administered topically twice a day was performed in 40 cats. cats, suffering from ... | 2016 | 27760032 |
| isolation and identification of microsporum canis from asian elephants (elephas maximus) in the chongqing zoo, china. | skin diseases affect millions of people and animals worldwide, including asian elephants. this study sought to determine the pathogen of skin diseases that occurred in asian elephants in chongqing zoo, china. the isolated fungus was identified through its cultural characteristics, morphology, and polymerase chain reaction (pcr) amplification. the pcr amplification using common fungal primers (its1 and its4) determined that the pathogen was 99.7% homologous to microsporum canis. this is the first ... | 2016 | 27691957 |
| [tinea in the genital area : a diagnostic and therapeutic challenge]. | pubogenital tinea or tinea genitalis represents a rare type of dermatophytosis which, however, is increasingly being diagnosed. the mons pubis is affected, but also the outer regions to the penis shaft and the labia together with the groins. pubogenital tinea is a more superficial erythrosquamous type, but strong inflammatory dermatomycoses of the genital area as tinea genitalis profunda ranging to kerion celsi are observed. a total of 30 patients (14-63 years of age, 11 men and 19 women) with p ... | 2016 | 27488308 |
| prevalence of tinea capitis among school children in nok community of kaduna state, nigeria. | in recent years, the prevalence of tinea capitis, an infection of the scalp by dermatophytes, has increased in children worldwide. this cross-sectional study was carried out to determine the prevalence and risk factor of tinea capitis among school children in nok community of kaduna state, nigeria. a total of 100 children were screened and 45% were diagnosed to have tinea capitis after fungal culture and microscopy. the prevalence of tinea capitis among girls was higher (51.4%) than that among b ... | 2016 | 27471603 |
| antifungal effects of the biological agent pythium oligandrum observed in vitro. | dermatophytosis, commonly known as ringworm, is a superficial fungal skin disease and zoonosis. pythium oligandrum is a micromycete with mycoparasitic properties that is used in agriculture to control fungal infections on plants. formulations containing p oligandrum were also developed for the treatment of dermatophytoses, but only several case studies have been published. in order to document the process in simplified conditions in vitro, we investigated the effectiveness of p oligandrum agains ... | 2016 | 27418287 |
| modeling dermatophytosis in reconstructed human epidermis: a new tool to study infection mechanisms and to test antifungal agents. | dermatophytosis is a superficial fungal infection of keratinized structures that exhibits an increasing prevalence in humans and is thus requesting novel prophylactic strategies and therapies. however, precise mechanisms used by dermatophytes to adhere at the surface of the human epidermis and invade its stratum corneum are still incompletely identified, as well as the responses provided by the underlying living keratinocytes during the infection. we hereby report development of an in vitro mode ... | 2016 | 27760830 |
| antifungal activity of cleome gynandra l. aerial parts for topical treatment of tinea capitis: an in vitro evaluation. | cleome gynandra l. (capparaceae) is an edible weed used in uganda topically for its presumed antifungal activity against tinea capitis. the goal of this study was to determine if this plant possesses antifungal activity in vitro, since t. capitis is a pervasive infection among especially rural children. | 2016 | 27391957 |
| evaluation of dermoscopy in the diagnosis of naturally occurring dermatophytosis in cats. | a rapid, accurate screening test for dermatophytosis in cats is desirable in clinical and shelter medicine. in human dermatology, dermoscopy is used to identify dermatophyte-infected hairs by their characteristic comma hair appearance. similar "comma-like" hairs have been observed in infected cats. | 2016 | 27311364 |
| in vitro evaluation of antifungal susceptibility and keratinase, elastase, lipase and dnase activities of different dermatophyte species isolated from clinical specimens in iran. | the aims of this study were to evaluate the enzymatic activity of various dermatophyte species and their antifungal susceptibility profiles. a total of 60 dermatophyte isolates, including trichophyton mentagrophytes, trichophyton rubrum, microsporum canis and microsporum gypseum, were examined. fungal isolates were analysed for the production of keratinase, lipase, elastase and deoxyribonuclease (dnase). a broth microdilution method was performed on the basis of m38-a2 clinical and laboratory st ... | 2016 | 27291045 |
| detection of common dermatophytes in clinical specimens using a simple quantitative real-time taqman polymerase chain reaction assay. | dermatophytes are common fungal pathogens causing mostly superficial infections in humans with a high prevalence worldwide. traditional detection techniques are time-consuming and insensitive, whereas molecular detection methods have proved to be much more rapid and sensitive. | 2016 | 26406273 |
| characterization of clinically important dermatophytes in north of iran using pcr-rflp on its region. | dermatophytosis is considered as one of the major public health problems in the world. accurate identification of the dermatophytes species is important for recognition of the environment and animal sources of infection. in this survey, 1500 clinical specimens taken from outpatients suspected of dermatophytosis and they were examined by direct microscopy and culture. | 2016 | 27496524 |
| molecular characterization and in vitro antifungal susceptibility of 316 clinical isolates of dermatophytes in iran. | dermatophytosis is a common mycotic infection of the skin, nail, and hair, associated with major public health concern worldwide. various species of dermatophytes show significant differences in susceptibility to antifungals. here, we present the antifungal susceptibility of a large collection of molecularly identified dermatophyte isolates obtained from tropical region of south of iran. a total of 9485 patients clinically suspected to have cutaneous fungal infections were examined. dermatophyto ... | 2016 | 26369643 |
| antidermatophytic action of resorcinol derivatives: ultrastructural evidence of the activity of phenylethyl resorcinol against microsporum gypseum. | in this work, we evaluated the antidermatophytic activities of three resorcinol derivatives that have a history of use in dermo-cosmetic applications to discover molecules with multiple dermatological activities (i.e., multi-target drugs), thereby reducing the cost and time necessary for new drug development. the antidermatophytic activities of the three skin lighteners were evaluated relative to the known antifungal drug fluconazole on nine dermatophytes responsible for the most common dermatom ... | 2016 | 27706019 |
| computational analysis of conserved coil functional residues in the mitochondrial genomic sequences of dermatophytes. | dermatophyte is a group of closely related fungi that have the capacity to invade keratinized tissue of humans and other animals. the infection known as dermatophytosis, caused by members of the genera microsporum, trichophyton, and epidermophyton includes infection to the groin (tinea cruris), beard (tinea barbae), scalp (tinea capitis), feet (tinea pedis), glabrous skin (tinea corporis), nail (tinea unguium), and hand (tinea manuum). the identification of evolutionary relationship between thes ... | 2016 | 28149055 |
| epidemiological aspects of dermatophytosis in khuzestan, southwestern iran, an update. | dermatophytosis is among the most common superficial mycoses in iran. the purpose of this report was to update the clinical and mycological features of human dermatophytosis in the khuzestan, southwestern iran. in the framework of a one-year survey, a total of 4120 skin, hair and nail samples obtained from the outpatients with symptoms suggestive of tinea were analyzed by using direct microscopy, culture and molecular identification methods. strains isolated from cultures were subjected to ampli ... | 2016 | 26886443 |
| phylogenetic analysis of dermatophyte species using dna sequence polymorphism in calmodulin gene. | use of phylogenetic species concepts based on rdna internal transcribe spacer (its) regions have improved the taxonomy of dermatophyte species; however, confirmation and refinement using other genes are needed. since the calmodulin gene has not been systematically used in dermatophyte taxonomy, we evaluated its intra- and interspecies sequence variation as well as its application in identification, phylogenetic analysis, and taxonomy of 202 strains of 29 dermatophyte species. a set of primers wa ... | 2016 | 26868901 |
| in vitro antimicrobial activities of animal-used quinoxaline 1,4-di-n-oxides against mycobacteria, mycoplasma and fungi. | the quinoxaline 1,4-di-n-oxides (qdnos) were known as potent antibacterial agents. for the purpose of evaluating the bioactivity of existing animal-used qdnos drugs against representative pathogenic microorganism, the representative drugs of quinoxalines including cyadox, mequindox, quinocetone and their metabolites were submitted to the in vitro evaluation for antituberculosis, antimycoplasma, antifungal and antiviral activities. | 2016 | 27600955 |
| enzymatic and non-enzymatic virulence activities of dermatophytes on solid media. | dermatophytes are keratinophilic fungi causing superficial cutaneous infections that account 20-25% of the global population. as per literature search, there is a dearth in the study on virulence factors of dermatophytes from the indian sub-continent and moreover the association of the virulence factors and the host tissue in vitro helps in understanding the host-pathogen interaction. | 2017 | 28384862 |
| development of enzyme immunoassays (elisa and western blot) for the serological diagnosis of dermatophytosis in symptomatic and asymptomatic cats. | dermatophytosis is the most common fungal infection in cats worldwide and plays an important role in both animal and human health due to their high zoonotic potential. effective screening is a strong preventive measure and the fungal culture is quite useful but requires full laboratorial experience and it takes a long time to obtain the result. a rapid and accurate screening test for dermatophytosis in cats is crucial for the effective control of disease outbreaks. the aim of this study was to d ... | 2017 | 28340215 |
| anti-fungal potential of ozone against some dermatophytes. | dermatophytes are classified in three genera, epidermophyton, microsporum and trichophyton. they have the capacity to invade keratinized tissue to produce a cutaneous infection known as dermatophytoses. this investigation was performed to study the effect of gaseous ozone and ozonized oil on three specific properties of six different dermatophytes. these properties included sporulation, mycelia leakage of sugar and nutrients and the activity of their hydrolytic enzymes. generally, ozonized oil w ... | 2017 | 27287337 |
| inibitory effects of linalool on fungal pathogenicity of clinical isolates of microsporum canis and microsporum gypseum. | in humans worldwide, microsporum sp. is a frequent agent of dermatophytsosis. when considering the emergence of resistant fungi and the clinical relevance of dermatophytosis, terpene antifungal activity is of great interest. linalool is a monoterpene alcohol with pharmacological properties. in this study, antifungal in vitro activity of linalool and ketoconazole (as a positive control) were evaluated against clinical isolates of m. canis and m. gypseum. the minimum inhibitory concentration (mic) ... | 2017 | 28198097 |
| intra-abdominal fungal pseudomycetoma in two cats. | pseudomycetomas are deep cutaneous to subcutaneous lesions caused by microsporum canis mainly described in persian cats, with few reports of intra-abdominal location. this report describes the clinical signs and lesions of intra-abdominal pseudomycetomas caused by m. canis in two persian cats. | 2017 | 28214274 |
| evaluation of growth conditions and dna extraction techniques used in the molecular analysis of dermatophytes. | recent molecular methods for diagnosis of superficial mycoses have determined the need for a rapid and easy method of extracting dna. the aim of study was to determine growth conditions and techniques of dna extraction for microsporum canis, trichophyton mentagrophytes and t. verrucosum. | 2017 | 28236353 |
| changing in the epidemiology of tinea capitis among school children in egypt. | tinea capitis remains a prevalent health problem among school-aged children. | 2017 | 28223741 |
| ultraviolet dermoscopy for the diagnosis of tinea capitis. | 2017 | 28087021 | |
| decontamination of carpet exposed to microsporum canis hairs and spores. | objectives the objective of this study was to evaluate the efficacy of vacuuming and three carpet cleaning methods for the removal of microsporum canis spores and hairs from experimentally contaminated carpets. methods sterile berber carpeting was artificially contaminated with naturally infective m canis hairs and spores. carpet swatches were vacuumed for 10 s, 30 s and 60 s, and then cultured. three carpet cleaning methods were evaluated on area rugs experimentally contaminated with infective ... | 2017 | 26927817 |
| antimicrobial metal-based thiophene derived compounds. | a novel series of thiophene derived schiff bases and their transition metal- [co(ii), cu(ii), zn(ii), ni(ii)] based compounds are reported. the schiff bases act as tridentate ligands toward metal ions via azomethine-n, deprotonated-n of ammine substituents and s-atom of thienyl moiety. the synthesized ligands along with their metal complexes were screened for their in vitro antibacterial activity against six bacterial pathogens (escherichia coli, shigella flexneri, pseudomonas aeruginosa, salmon ... | 2017 | 27766891 |
| cutaneous blastomycosis and dermatophytic pseudomycetoma in a persian cat from bangkok, thailand. | this is a case report of concurrent of blastomycosis and pseudomycetoma in a 3 year-old persian cat from bangkok, thailand. histopathology from antemortem and postmortem samples revealed blastomycosis and dermatophyte pseudomycetoma. the pcr analysis of the formalin-embedded tissue of antemortem sample confirmed that blastomycosis was caused by blastomyces dermatitidis. dermatophyte infection was caused by microsporum canis. according to the author's knowledge, this is the first case of blastomy ... | 2017 | 28116230 |
| antidermatophytic and protease-inhibiting activities of zerumbone: a natural sesquiterpene from the rhizome of zingiber zerumbet (l.) roscoe ex j.e; smith. | due to increase in the number of patients with impaired immunity, incidence of dermatophytoses has increased considerably. antidermatophytic agents with anti-inflammatory and protease-inhibiting activities will help in restricting inflammatory response associated with dermatophytoses. | 2017 | 28216875 |
| composition, antifungal and antiproliferative activities of the hydrodistilled oils from leaves and flower heads of pterocephalus nestorianus nab. | this paper reports the first study of the chemical composition, and antifungal and antiproliferative properties of the volatile extracts obtained by hydrodistillation of the flower heads and leaves of the traditional kurdish medicinal plant p. nestorianus nab., collected in the wild. a total of fifty-five constituents, 43 of the flower heads' oil (pfo) and 46 of the leaves' oil (plo), respectively, were identified by gc/ms, constituting 99.68% and 99.04% of the two oils, respectively. the oils w ... | 2017 | 28217981 |
| the changing face of dermatophytic infections worldwide. | dermatophytes evolve along with the geography and socioeconomic conditions. epidermophyton floccosum, microsporum audouinii and trichophyton schoenleinii acted as the major pathogens of superficial fungal diseases 100 years ago, but their frequency decreased dramatically since the middle of the twentieth century and they are limited to some less-developed countries nowadays; meanwhile, frequency of trichophyton rubrum, trichophyton interdigitale, trichophyton tonsurans and microsporum canis incr ... | 2017 | 27783316 |
| inhibition of dermatophytes by photodynamic treatment with curcumin. | treatment of dermatophytoses with currently available antimycotic agents is often tedious and sometimes unsatisfactory. a search for better therapeutic methods-ideally with an immediate fungicidal effect-has, among others, lead to photodynamic procedures as a promising alternative, and recently curcumin was found to be a suitable agent for this application. in this study the effect of photodynamic treatment with curcumin on dermatophytes was tested in vitro wells of microtiter plates were filled ... | 2017 | 28053148 |
| chemical characterisation and biological activity of leaf essential oils obtained from pistacia terebinthus growing wild in tunisia and sardinia island. | in the present work the chemical compositions, measured by gc and gc-ms, of the essential oils obtained by hydrodistillation from leaves of pistacia terebinthus collected in bizerte (tunisia) and baunei (italy) are reported. both essential oils possessed high content of monoterpene hydrocarbons (86.3% and 90.9%, respectively), being α-pinene (62.4 vs. 35.0)%, camphene (3.0 vs. 2.4)%, β-pinene (12.1 vs. 4.5)%, terpinolene (1.7 vs. 35.2)% and β-phellandrene (3.8 vs. 4.5)% the main components. the ... | 2017 | 28278668 |
| antifungal activity of lactobacillus against microsporum canis, microsporum gypseum and epidermophyton floccosum. | a total of 220 lactic acid bacteria isolates were screened for antifungal activity using aspergillus fumigatus and aspergillus niger as the target strains. four lactobacillus strains exhibited strong inhibitory activity on agar surfaces. all four were also identified as having strong inhibitory activity against the human pathogenic fungi microsporum canis, microsporum gypseum and epidermophyton floccosum. one of the four lactobacilli, namely lb. reuteri ee1p exhibited the most inhibition against ... | 2017 | 22539027 |
| nimesulide inhibits pathogenic fungi: pge2-dependent mechanisms. | certain non-steroidal anti-inflammatory drugs can inhibit fungal growth, fungal prostaglandin e2 production, and enzyme activation. this study aims to investigate the antifungal effect of nimesulide against pathogenic filamentous fungi and yeast. the experiments detailed below were also designed to investigate whether the action is dependent on e2 fungal prostaglandins. our data showed that nimesulide exhibited potent antifungal activity, mainly against trichophyton mentagrophytes (atcc 9533) an ... | 2017 | 27866353 |
| in vitro efficacy of shampoos containing miconazole, ketoconazole, climbazole or accelerated hydrogen peroxide against microsporum canis and trichophyton species. | objectives the objective was to evaluate the antifungal efficacy of shampoo formulations of ketoconazole, miconazole or climbazole and accelerated hydrogen peroxide wash/rinse against microsporum canis and trichophyton species spores. methods lime sulfur (1:16)-treated control, enilconazole (1:100)-treated control, accelerated hydrogen peroxide (ahp 7%) 1:20 and a 1:10 dilution of shampoo formulations of miconazole 2%, miconazole 2%/chlorhexidine gluconate 2-2.3%, ketoconazole 1%/chlorhexidine 2 ... | 2017 | 26809882 |
| antifungal activity of silver nanoparticles on fluconazole resistant dermatophytes identified by (gaca)4 and isolated from primary school children suffering from tinea capitis in ismailia - egypt. | fungal infections caused by dermatophytes recently became more common. available antifungal drugs are limited because of emergence of resistant strains due to prophylaxis with them, so there is an urgent need for novel antifungals. this study is aimed to detect the antifungal activity of silver nanoparticles (snps) on fluconazole resistant dermatophytes isolated from primary school children clinically suffering from tinea capitis and attending el-sheikh zaid dermatology center in ismailia. the s ... | 2017 | 29208175 |
| flavonoid composition and biological activities of ethanol extracts of caryocar coriaceum wittm., a native plant from caatinga biome. | caryocar coriaceum fruits, found in brazilian cerrado and caatinga, are commonly used as food and in folk medicine, as anti-inflammatory, bactericide, fungicide, leishmanicide, and nematicide. due to the biological potential of this plant, this study focuses on the evaluation of antifungal and antileishmanial activities, including anticholinesterase and antioxidant tests, correlating with total phenols and flavonoids content. peel extracts contain higher yield of phenols and flavonoids as analyz ... | 2017 | 29081821 |
| prp8 intein in dermatophytes: evolution and species identification. | dermatophytes are keratinophilic fungi belonging to the family arthrodermataceae. despite having a monophyletic origin, its systematics has always been complex and controversial. sequencing of nuclear ribosomal its and d1/d2 rdna has been proposed as an efficient tool for identifying species in this group of fungi, while multilocus analyses have been used for phylogenetic species recognition. however, the search for new markers, with sequence and size variation, which enable species identificati ... | 2017 | 29228309 |
| in vivoevaluation ofgalla chinensissolution in the topical treatment of dermatophytosis. | dermatophytosis is one of the main fungal diseases in humans and animals all over the world.galla chinensis, a traditional medicine, has various pharmacological effects. the goal of this study was to evaluate the treatment effect ofgalla chinensissolution (gcs) on dermatophytosis-infected dogs (microsporum canis,microsporum gypseum, andtrichophyton mentagrophytes, resp.). | 2017 | 29259645 |
| infection by microsporum canis in paediatric patients: a veterinary perspective. | microsporum canisis a dermatophyte fungus of which cats and dogs are recognized as the natural hosts.m. canisis also easily transmitted to humans, causing lesions to the glabrous skin (tinea corporis) and to the head (tinea capitis). the present study describes some cases of infection withm. canisin children from a veterinary perspective, highlighting some important features of this clinical entity (e.g., the necessity to identify the animal source of infection with appropriate diagnostic tests; ... | 2017 | 29056704 |
| tinea capitis by microsporum audouinii: case reports and review of published global literature 2000-2016. | tinea capitis caused by microsporum audouinii is reported herein from two brazilian schoolchildren, which are brothers. arthroconidia were evidenced on direct examination of scalp hair, and a fungus of the genus microsporum was isolated from cultures of each patient. the isolated fungi were classified as m. audouinii by visualization of species-specific structures, including: pectinate hyphae, chlamydospores, and fusiform macroconidia, sterile growth with characteristic brown pigment in rice gra ... | 2017 | 28736794 |
| [tinea capitis: main mycosis child. epidemiological study on 10years]. | despite the changes in their epidemiology, and the improving level of hygiene of the population, tinea capitis is still considered a public health problem in our country, and is the most common type of dermatophytosis in our country. the aim of our study was to evaluate the epidemiological, clinical and mycological features of tinea capitis in children encountered in the tunis region. a retrospective study concerned 1600 children aged 6 months to 15 years suspected to have tinea capitis was cond ... | 2017 | 28501468 |
| an invertebrate infection model for evaluating anti-fungal agents against dermatophytosis. | animal models of pathogenic infection are needed to evaluate candidate compounds for the development of anti-infectious drugs. dermatophytes are pathogenic fungi that cause several infectious diseases. we established a silkworm dermatophyte infection model to evaluate anti-fungal drugs. injection of conidia of the dermatophyte arthroderma vanbreuseghemii into silkworms was lethal. a. vanbreuseghemii conidia germinated in liquid culture were more potent against silkworms than non-germinated conid ... | 2017 | 28947778 |
| biosynthesis of zinc oxide nanoparticles by petals extract of rosa indica l., its formulation as nail paint and evaluation of antifungal activity against fungi causing onychomycosis. | aim: the authors report the biological synthesis of zinc oxide nanoparticles (zno-nps) from the petals extract of rosa indica l. (rose). its efficacy was evaluated against two dermatophytes: namely: trichophyton mentagrophytes and microsporum canis which cause onychomycosis. the activity of antibiotics against the tested dermatophytes was enhanced, when evaluated in combination with zno-nps. methods and results: the synthesised zno-nps were preliminary detected by using ultraviolet uv visible sp ... | 2017 | 28477005 |
| assessment of real-time pcr cycle threshold values in microsporum canis culture-positive and culture-negative cats in an animal shelter: a field study. | objectives real-time pcr provides quantitative information, recorded as the cycle threshold (ct) value, about the number of organisms detected in a diagnostic sample. the ct value correlates with the number of copies of the target organism in an inversely proportional and exponential relationship. the aim of the study was to determine whether ct values could be used to distinguish between culture-positive and culture-negative samples. methods this was a retrospective analysis of ct values from d ... | 2017 | 28425361 |
| evaluation of zanthoxylum armatum roxb for in vitro biological activities. | zanthoxylum armatum fruits are used traditionally as a spice in various food preparations. the aim of this study was analysis of antimicrobial, cytotoxic, phytotoxic, insecticidal, and anti-leishmanial activity. the crude extract showed 86 ± 10% antifungal activity (agar tube dilution method) against trichophyton longifusis while n-hexane, chloroform, and aqueous-methanol fractions inhibited this pathogen by 90 ± 7, 85 ± 10 and 70 ± 9% respectively. the n-hexane and aqueous-methanol fraction als ... | 2017 | 29034201 |
| evaluation of incubation time for microsporum canis dermatophyte cultures. | objectives the goal of this study was to determine how frequently microsporum canis was isolated after 1, 2 and 3 weeks of incubation on dermatophyte culture medium either from untreated cats or cats during treatment. methods this was an observational retrospective study. toothbrush fungal culture results were examined from two data pools: untreated cats with suspect skin lesions and weekly fungal cultures from cats being treated for dermatophytosis. results results from 13,772 fungal cultures w ... | 2017 | 28920535 |
| antimicrobial activity of essential oil and aqueous and ethanol extracts ofteucrium poliuml. subsp.gabesianum(l.h.) from tunisia. | the antimicrobial effects of essential oil, ethanol and aqueous extracts ofteucrium poliuml. were investigated against 13 microorganisms. extracts and essential oil were obtained from maceration, decoction and hydrodistillation respectively. samples were tested for their antimicrobial activity using the disk diffusion, the agar dilution and the agar incorporation method. essential oil was analysed using gc/ms, results showed that β-pinene (35.97%) and α-pinene (13.32%) were the main components. ... | 2017 | 28878510 |
| kerion celsi due to microsporum canis with a dermatophytid reaction. | microsporum (m.) canis is the most common fungus to cause tinea capitis in europe, especially in the mediterranean region and south and central europe. fungal scalp infections caused by m. canis tend to be non-inflammatory. recently, a growing number of cases of tinea capitis characterized by inflammatory infection caused by m. canis and m. gypseum have been registered. we present a case of highly inflammatory tinea capitis, also known as kerion celsi, caused by m. canis in a 6-year-old-patient. ... | 2017 | 28871931 |
| tinea capitis in children and trichoscopic criteria. | tinea capitis is the most common pediatric superficial dermatophyte infection. the causative species vary, as for instance, microsporum canis predominates in europe, while trichophyton tonsurans predominates in north america. tinea capitis does not respond well to topical therapy alone, thus oral therapy is requisite. the drug of choice is griseofulvin; however in some countries, it is no longer available. fungal culture should be requested in the persistent, scalp lesion and trichoscopy can put ... | 2017 | 28839385 |
| quantitative and structural analyses of the in vitro and ex vivo biofilm-forming ability of dermatophytes. | the aim of this study was to evaluate the in vitro and ex vivo biofilm-forming ability of dermatophytes on a nail fragment. | 2017 | 28708048 |
| molecular epidemiology of microsporum canis isolated in japan based on multilocus microsatellite typing fragment analysis. | intraspecies polymorphisms of microsporum canis strains isolated from human lesions and domesticated cats in japan were examined by multilocus microsatellite (ms) analysis. using nine ms markers, 70 strains were classified into 20 genotypes (genotypes a to t). of the nine ms markers, five were useful for genotyping, whereas the other four were not. the combination of ms2, ms4 and ms7 has the highest resolution power for inter-strain differentiation. genotype a, present in 15 strains (21.4%), was ... | 2017 | 28674311 |
| biofilm formation by microsporum canis. | 2017 | 28642143 | |
| epidemiological profile of tinea capitis in são paulo city. | tinea capitis is the most common fungal infection in children. the identification of the etiologic agent helps clinicians make their therapeutic choice. studies conducted in different countries show a changing pattern of the main etiological agents according to their regions. we performed a retrospective study in the tertiary public service in são paulo, analyzing the isolated etiological agents in patients with tinea capitis from march 2013 to may 2015. microsporum canis was the main agent (56. ... | 2017 | 28538903 |
| common dermatophytes and in vitro anti-fungal susceptibility testing in patients attending the dermatological clinic at the hospital for tropical medicine, bangkok. | dermatophytes comprising the genera trichophyton, microsporum, and epidermophyton are important causes of superficial mycoses. the number of infected patients and the distribution of species of these organisms in our hospital were unknown. we therefore aimed to investigate the clinical pattern of dermatophyte infections and to identify the species of these dermatophytes at the dermatological clinic of the hospital for tropical medicine, faculty of tropical medicine, mahidol university, bangkok i ... | 2017 | 28513812 |
| in vitroantifungal activity of hexahydropyrimidine derivatives against the causative agents of dermatomycosis. | nitrogenated heterocyclic compounds are present in both natural and synthetic drugs, and hexahydropyrimidine derivatives may prove to be efficient in treating dermatomycosis causing fungi. this study evaluated the antifungal activity of four hexahydropyrimidine derivatives against the dermatomycosis causing fungi. these derivatives were synthesized, characterized, and assessed in terms of their activity againsttrichophyton mentagrophytes,microsporum canis,microsporum gypseum,trichophyton rubrum, ... | 2017 | 29226215 |
| chemical composition, antibacterial and antifungal activities of crude dittrichia viscosa (l.) greuter leaf extracts. | the small amount of data regarding the antifungal activity of dittrichia viscosa (l.) greuter against dermatophytes, malassezia spp. and aspergillus spp., associated with the few comparative studies on the antimicrobial activity of methanolic, ethanolic, and butanolic extracts underpins the study herein presented. the total condensed tannin (tct), phenol (tpc), flavonoid (tfc), and caffeoylquinic acid (cqc) content of methanol, butanol, and ethanol (80% and 100%) extracts of d. viscosa were asse ... | 2017 | 28665341 |
| tinea folliculorum complicating tinea of the glabrous skin: an important yet neglected entity. | dermatophytes are capable of infecting the skin and its appendages such as nails and hairs producing a variety of clinical conditions. hair invasion by dermatophytes is a key feature of tinea capitis and tinea barbae but not of tinea of glabrous skin. in this project, we studied the clinico-mycological aspects of follicular involvement in patients with dermatophytosis of the glabrous skin. in total, 16 patients, eight males and eight females, were included in the study. all were adults except fo ... | 2017 | 29087496 |
| efficacy of itraconazole oral solution using an alternating-week pulse therapy regimen for treatment of cats with experimental microsporum canis infection. | objectives the objective of this study was to evaluate itraconazole 10 mg/ml oral solution for the treatment of microsporum canis infection using an alternating-week pulse therapy regimen in a controlled laboratory setting. methods eighty cats with experimentally induced infections were randomly assigned to treatment (itraconazole vs control [sterile water]), administered 5 mg/kg orally once daily for 1 week on alternate weeks for 5 weeks, followed by a 4 week follow-up period. topical therapeut ... | 2017 | 29025320 |
| epidemiological status of dermatophytosis in guilan, north of iran. | the epidemiological features of dermatophytoses have been characterized in many geographical locations of iran, but not in guilan, north of iran. this study was carried out to determine the distribution pattern of dermatophytoses and their relevant agents in guilan, north of iran, over a period of one year, from april 2010 to april 2011. | 2017 | 29302626 |
| epidemiology of dermatophyte infections among school children in menoufia governorate, egypt. | most superficial mycotic infections of human skin are due to dermatophytes. children are frequently affected due to different predisposing factors, particularly overcrowding in classrooms. this study aimed to estimate the prevalence of dermatophytes infections and their related risk factors among school children in menoufia governorate, egypt. six public primary and preparatory schools were randomly selected and their pupils (n = 3464) were asked to complete a predesigned questionnaire covering ... | 2018 | 29314351 |
| resistance mechanism in a terbinafine-resistant strain of microsporum canis. | to clarify the terbinafine (trf) resistance mechanism in a trf-resistant strain of microsporum canis, the expression of the pleiotropic drug resistance (pdr1), multidrug resistance (mdr1), mdr2 and mdr4 genes were investigated by real-time quantitative pcr (rt-qpcr) analysis, given the known interaction of the corresponding proteins with antifungals and with the efflux blocker fk506. the expression of the pdr1, mdr1, mdr2 and mdr4 genes was 2-4 times higher in the trf-resistant strain grown in t ... | 2018 | 29340910 |
| comparison of real-time pcr with fungal culture for the diagnosis of microsporum canis dermatophytosis in shelter cats: a field study. | objectives fungal culture requires at least 14 days for a final result, compared with 1-3 days for pcr. the study compared a commercial real-time dermatophyte pcr panel with fungal culture in cats in a shelter setting for: (1) diagnosis of microsporum canis infection; and (2) determination of mycological cure. methods this was a cross-sectional, observational study of cats with suspicious skin lesions or suspected exposure to dermatophytosis. hair samples were collected for fungal culture and pc ... | 2018 | 29172910 |
| genus- and species-level identification of dermatophyte fungi by surface-enhanced raman spectroscopy. | this paper demonstrates that surface-enhanced raman spectroscopy (sers) coupled with principal component analysis (pca) can serve as a fast and reliable technique for detection and identification of dermatophyte fungi at both genus and species level. dermatophyte infections are the most common mycotic diseases worldwide, affecting a quarter of the human population. currently, there is no optimal method for detection and identification of fungal diseases, as each has certain limitations. here, fo ... | 2018 | 29156315 |
| characterizing the clinical isolates of dermatophytes in hamadan city, central west of iran, using pcr-rlfp method. | dermatophytosis is one of the most common mycotic infections, which considered as a public health problem in the major of countries. this study evaluated the molecular epidemiology of dermatophytosis in patients referred to farshchian hospital in hamadan city with pcr-rflp method. | 2018 | 29439839 |
| activity of salvia dolomitica and salvia somalensis essential oils against bacteria, molds and yeasts. | essential oils (eos) fromsalvia dolomiticaandsalvia somalensis, widely employed in the cosmetic and perfume industry, were analyzed for composition and tested against bacterial and fungal pathogens isolated from clinical and environmental specimens. the analyses were carried out againststaphylococcus aureus,staphylococcus pseudointermedius,pseudomonas aeruginosa,escherichia coli,streptococcus canis,streptococcus pyogenes,klebsiella pneumoniae,proteus mirabilis,microsporum canis,microsporum gypse ... | 2018 | 29438274 |
| selection and validation of reference genes for qrt-pcr analysis of gene expression in microsporum canis growing under different adhesion-inducing conditions. | dermatophytes are the group of filamentous fungi infecting keratinized structures such as skin, hair, and nails. knowledge about genes and molecular mechanisms responsible for pathogenicity, as well as other biological properties of microsporum canis is still relatively poor. the qrt-pcr is a reliable technique for quantifying gene expression across various biological processes, and choosing a set of suitable reference genes to normalize the expression data is a crucial step of this technique. w ... | 2018 | 29352152 |
| in vitro evaluation of new 2-phenoxy-benzo[g][1,2,4]triazolo[1,5-a]quinazoline derivatives as antimicrobial agents. | previously, seventeen 2-phenoxy-benzo[g][1,2,4]triazolo[1,5-a]quinazoline derivatives were prepared and characterized by physicochemical and spectral means. this study was conducted to evaluate their activities in vitro against five gram-negative and five gram-positive of clinically pathogenic bacterial strains and ten fungal strains. the antimicrobial activity was assessed, and the minimum inhibitory concentration values of the tested compounds were determined in μg ml-1, using the diffusion ag ... | 2018 | 29432912 |
| infant case of tinea faciei caused by microsporum canis. | 2018 | 29411427 | |
| correction to: resistance mechanism in a terbinafine-resistant strain of microsporum canis. | in the initial online publication, the name of author hock siew han was given incorrectly as han hock siew. the original article has been corrected. | 2018 | 29380187 |