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the biochemical role and hypocholesterolaemic potential of the legume cassia fistula in hypercholesterolaemic rats.the hypocholesterolaemic effect of cassia fistula was investigated using hypercholesterolaemic male albino rats. hypercholesterolaemia was induced by feeding on a mixture of cholesterol plus cholic acid for a 12 weeks period. hypercholesterolaemia was characterized by significant increase in the average levels of total lipids, total cholesterol, and triglycerides and significant decrease in phospholipids content. administration of cassia fistula significantly reduced blood and liver total lipids ...19911780005
[evaluation of traditional medicine: effects of cajanus cajan l. and of cassia fistula l. on carbohydrate metabolism in mice].the authors report the results of pharmacologic evaluation of two medicinal plants: cajanus cajan (l.) millsp and cassia fistula, which are used in panamanian folk medicine for the treatment of diabetes. it was found that the aqueous fraction of the leaves and stems of c. cajan did not produce any hypo blood sugar effect in normoglycemic mice; instead, it produced a hyperglycemia with doses of 500 mg/kg and 1000 mg/kg (p less than 0.001). only with a dose of 300 mg/kg a short lived decrease in t ...19912024054
structure of fistulic acid, a new colouring matter from the pods of cassia fistula. 19725018491
galactomannan from the seeds of cassia fistula. 19725083251
antipyretic and analgesic activities of aconitum spicatum and cassia fistula. 19655885002
bioassay of cassia fistula. l. (aragvadha). 19665974956
studies on the possibilities to infect the cells of callus of cassia fistula by an animal virus & induce production of interferon-like antiviral factor(s). 19816168574
the indian laburnum (cassia fistula l.) fruit: an analysis of its chemical constituents.the edible fruit tissue of indian laburnum fruit (cassia fistula l.), a member of the leguminosae family, was analyzed for certain organic compounds and mineral nutrients. of the nine macro- and micronutrients studied, k was the most highly concentrated such that 100% of the us recommended dietary allowances (rda) for adults could be met by the consumption of about 100 g of the fresh fruit. na contents in pulp and seeds are relatively low. ca content at 827 mg per 100 g of dry matter is one of t ...19957784398
screening of 34 indian medicinal plants for antibacterial properties.a total of 34 plant species belonging to 18 different families, selected on the basis of folklore medicinal reports practised by the tribal people of western ghats, india, were assayed for antibacterial activity against escherichia coli, klebsiella aerogenes, proteus vulgaris, and pseudomonas aerogenes (gram-negative bacteria) at 1000-5000 ppm using the disc diffusion method. of these 16 plants showed activity; among them cassia fistula, terminalia arjuna and vitex negundo showed significant ant ...19989741889
evaluation of hepatoprotective activity of cassia fistula leaf extract.hepatoprotective activity of the n-heptane extract of cassia fistula leaves was investigated in rats by inducing hepatotoxicity with carbon tetrachloride:liquid paraffin (1:1). the extract has been shown to possess significant protective effect by lowering the serum levels of transminases (sgot and sgpt), bilirubin and alkaline phosphatase (alp). the extract of c. fistula at a dose of 400 mg/kg showed significant hepatoprotective activity which was comparable to that of a standard hepatoprotecti ...199910473173
effect of solvent residues of vitex negundo linn. and cassia fistula linn. on pulse beetle, callosobruchus maculatus fab. and its larval parasitoid, dinarmus vagabundus (timberlake).effect of solvent residues of vitex negundo l. and cassia fistula l. leaves (0.5 and 1%) was studied on egg laying and adult emergence of callosobruchus maculatus fab. and on percentage of larval parasitism by dinarmus vagabundus (timberlake). cowpea seeds treated with methanol and aqueous extract of vitex, at these concentrations (0.5 and 1%), significantly reduced the number of eggs and emergence of f1 adults of c. maculatus. both vitex and cassia extracts did not affect the percentage of para ...200010927878
antitumor activity of methanolic extract of cassia fistula l. seed against ehrlich ascites carcinoma.effects of methanolic extract (me) of cassia fistula seed on the growth of ehrlich ascites carcinoma (eac) and on the life span of tumor bearing mice were studied. me treatment showed an increase of life span, and a decrease in the tumor volume and viable tumor cell count in the eac tumor hosts. cytological studies have revealed a reduction in the mitotic activity, and the appearance of membrane blebbing and intracytoplasmic vacuoles in the treated tumor cells. improvement in the hematological p ...200010967466
defense proteins from seed of cassia fistula include a lipid transfer protein homologue and a protease inhibitory plant defensin.a novel trypsin inhibitor was extracted from the seeds of cassia fistula by a process successively involving soaking seeds in water, extraction of the seeds in methanol, and extraction of the cell wall material at high ionic strength. the protease inhibitor (pi) was subsequently purified by chromatography on carboxymethylcellulose, gel filtration and reversed phase hplc (rp-hplc). electrospray ionization mass spectrometry (esms) of the oxidized from of the pi yielded an average molecular mass of ...200011074277
antifertility effect of aqueous extract of seeds of cassia fistula in female rats.oral administration of aqueous extract of seeds of cassia fistula to mated female rats from day 1-5 of pregnancy at the doses of 100 and 200 mg/kg body weight resulted in 57.14% and 71.43% prevention of pregnancy, respectively, whereas 100% pregnancy inhibition was noted at 500 mg/kg bw. in the uterine bioassay test carried out in immature bilaterally ovariectomized female rats, aqueous extract of seeds of cassia fistula (100 mg/kg bw) increased the uterine wet weight (p<0.05) and luminal epithe ...199911145371
hepatoprotective activity of cassia fistula leaf extract.hepatoprotective activity of the n-heptane extract of cassia fistula leaves was investigated by inducing hepatotoxicity with paracetamol in rats. the extract at a dose of 400 mg/kg body wt. exhibited orally, significant protective effect by lowering the serum levels of transaminases (sgot and sgpt), bilirubin and alkaline phosphatase (alp). the effects produced were comparable to that of a standard hepatoprotective agent.200111417916
antiradical and antilipoperoxidative effects of some plant extracts used by sri lankan traditional medical practitioners for cardioprotection.reactive oxygen species (ros) are implicated in many pathogenic processes including the cardiovascular system. detoxification of ros by antioxidants (ao) therefore affords protection against such diseases. there is a growing body of evidence suggesting that antioxidants contribute to cardioprotection. therefore, nine plants that are components of ayurvedic formulations used for the therapy of cardiovascular diseases were investigated to determine whether antioxidant activity is one of the mechan ...200111536382
common environmental allergens causing respiratory allergy in india.respiratory allergy affects all age groups but the children are the worst affected by the respiratory allergy. bioparticles from different biological sources are the main cause of allergy. pollen grains, fungal spores, insect and other materials of biological origin form the most important allergen load in the air. for the efficient diagnosis of the allergy and its effective treatment it is very important to know about the prevalence, seasonal and annual variations of aeroallergens of the area. ...200212003301
antioxidant activities of phenolic, proanthocyanidin, and flavonoid components in extracts of cassia fistula.cassia fistula l., a semi-wild indian labernum, is widely cultivated in mauritius as an ornamental tree for its beautiful bunches of yellow flowers and also used in traditional medicine for several indications. the total phenolic, proanthocyanidin, and flavonoid contents, and the antioxidant activities, of fresh vegetative and reproductive organs of cassia fistula harvested at different stages of growth were determined using the trolox equivalent antioxidant capacity (teac) and ferric-reducing a ...200212188605
four new compounds from the seeds of cassia fistula.four new compounds, 5-(2-hydroxyphenoxymethyl)furfural (1), (2's)-7-hydroxy-5- hydroxymethyl-2-(2'-hydroxypropyl)chromone (2), benzyl 2-hydroxy-3,6-dimethoxybenzoate (3), and benzyl 2beta-o-d-glucopyranosyl-3,6-dimethoxybenzoate (4), together with four known compounds, 5-hydroxymethylfurfural, (2's)-7-hydroxy-2-(2'-hydroxypropyl)-5-methylchromone, and two oxyanthraquinones, chrysophanol and chrysophanein, were isolated and identified from the seeds of cassia fistula. the structures of 1-4 were d ...200212193023
a new biologically active flavone glycoside from the seeds of cassia fistula (linn.).a new bioactive flavone glycoside 1 [mp 252-254 degrees c, c28h32o16, [m]+ 624 (eims)] was isolated from the acetone soluble fraction of the defatted seeds of cassia fistula (linn.). it was characterized as a new bioactive flavone glycoside 5,3',4'-tri-hydroxy-6-methoxy-7-o-alpha-l-rhamnopyranosyl-(1 --> 2)-o-beta-d-galactopyranoside by several colour reactions, spectral analysis and chemical degradations. compound 1 showed anti-microbial activity.200312608640
microscopic evaluation and seasonal variations of anthraquinone glycosides of cultivated cassia fistula linn.in this report, we present the results of the microscopy, seasonal variations and spectrophotometric estimation of hydroxy-anthraquinone glycosides of culitivated cassia fistula linn. the total glycoside contents ofthe morphological parts of this species at different stages of growth are also presented. the study shows that anthraquinone glycosides are concentrated in the leaves (1.75%) and flowers (1.58%) at peak flowering. notable seasonal variations were observed in the cultivated species. hy ...200614510141
screening for acetylcholinesterase inhibitory activity in plants used in thai traditional rejuvenating and neurotonic remedies.acetylcholinesterase (ache) inhibitor has been used as a drug for the symptomatic treatment of alzheimer's disease. in order to search for new ache inhibitors, 32 plants used in thai traditional rejuvenating and neurotonic remedies were collected. the plant methanolic extracts were tested for ache inhibitory activity using ellman's colorimetric method in 96-welled microplates. the results showed that the methanolic extracts from roots of stephania suberosa forman. and tabernaemontana divaricata ...200314611889
the effect of medicinal plants of islamabad and murree region of pakistan on insulin secretion from ins-1 cells.in vitro testing of the extracts of medicinal plants collected from islamabad and the murree region on insulin secretagogue activity was carried out. dried ethanol extracts of all plants (zh1-zh19) were dissolved in ethanol and dmso, and tested at various concentrations (between 1 and 40 microg/ml) for insulin release from ins-1 cells in the presence of 5.5 mm glucose. glibenclamide was used as a control. promising insulin secretagogue activity in various plant extracts at 1, 10, 20 and 40 micro ...200414750205
antioxidant activity of cassia fistula (linn.) flowers in alloxan induced diabetic rats.aqueous extract of cassia fistula (linn.) flowers (acf) was screened for its antioxidant effect in alloxan induced diabetic rats. an appreciable decrease in peroxidation products viz thiobarbituric acid reactive substances, conjugated dienes, hydroperoxides was observed in heart tissues of acf treated diabetic rats. the decreased activities of key antioxidant enzymes such as superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase and glutathione in diabetic rats were brough ...200415652272
isoprene emission from tropical tree species.foliar emission of isoprene was measured in nine commonly growing tree species of delhi, india. dynamic flow enclosure technique was used and gas samples were collected onto tenax-gc/carboseive cartridges, which were then attached to the sample injection system in the gas chromatograph (gc). eluting compounds were analysed using a flame ionisation detector (fid). out of the nine tree species, isoprene emission was found in six species (eucalyptus sp., ficus benghalensis, ficus religiosa, mangife ...200515701397
evaluation of air pollution phytotoxicity downwind of a phosphate fertilizer factory in india.the effects of air pollution on plants downwind of a fertilizer factory at udaipur, india, were studied using three woody perennials. seedlings of these species including a shrub (carissa carandas l.), a leguminous avenue tree (cassia fistula l.) and a fruit tree (psidium guajava l.) were grown in earthen pots at different study sites receiving varying levels of air pollution input. changes in plant growth, morphological characteristics, photosynthetic pigment, ascorbic acid, n and s contents an ...200515727311
effect of pretreatment of cassia fistula linn. leaf extract against subacute ccl4 induced hepatotoxicity in rats.ccl4 alone treatment (0.lml of liquid paraffin/100g body weight, ip) for 7 days followed by 0.l ml of ccl4 (in liquid parafiin/100g body weight, ip) from day 8 till day 14, caused a 16 fold increase in lipid peroxidation and a 50% reduction in catalase and glutathione reductase in liver tissue of rats accompanied by an increase in the activities of transaminases. alkaline phosphatase, lactate dehydrogenase and gamma - glutamyl transpeptidase in serum as compared to liquid paraffin treated contro ...200515991578
wound healing potential of cassia fistula on infected albino rat model.infection is the major problem to treat the wound. antibiotic resistance by the pathogenic microorganism renders drug ineffective and calls for improved designing and development of new drugs. new approach has been developed to isolate active components from botanicals. our aim was to investigate the potential of cassia fistula to treat the infected wound on albino rat model.200616242721
preliminary phytochemical screening of four common plants of family caesalpiniaceae.preliminary phytochemical screening of bauhinia variegata, cassia fistula, cassia tora and tamarindus indica did not reveal alkaloids and unbound anthraquinones while glycosides as well as flavonoids were present in all the four species of the family caesalpiniaceae. cardiac glycosides were absent only in c. tora and saponins were present only in t. indica, b. variegata and t. indica were devoid of bound anthraquinones while bound anthraquinones were present in c. fistula and c. tora. paper chro ...198916414637
search for antibacterial and antifungal agents from selected indian medicinal plants.a series of 61 indian medicinal plants belonging to 33 different families used in various infectious disorders, were screened for their antimicrobial properties. screening was carried out at 1000 and 500 microg/ml concentrations by agar dilution method against bacillus cereus var mycoides, bacillus pumilus, bacillus subtilis, bordetella bronchiseptica, micrococcus luteus, staphylococcus aureus, staphylococcus epidermidis, escherichia coli, klebsiella pneumoniae, pseudomonas aeruginosa, streptoco ...200616678369
ni(ii) biosorption by cassia fistula (golden shower) biomass.cassia fistula is a fast-growing, medium-sized, deciduous tree which is now widely cultivated worldwide as an ornamental tree for its beautiful showy yellow flowers. methods are required to reuse fallen leaves, branches, stem bark and pods when they start getting all over lawn. this investigation studies the use of these non-useful parts of c. fistula as naturally occurring biosorbent for the batch removal of ni(ii) in a well stirred system under different experimental conditions. the data showe ...200716860463
endophytic phomopsis species: host range and implications for diversity estimates.foliar endophyte assemblages of teak trees growing in dry deciduous and moist deciduous forests of nilgiri biosphere reserve were compared. a species of phomopsis dominated the endophyte assemblages of teak, irrespective of the location of the host trees. internal transcribed spacer sequence analysis of 11 different phomopsis isolates (ten from teak and one from cassia fistula) showed that they fall into two groups, which are separated by a relatively long branch that is strongly supported. the ...200616917524
phytoextraction capacity of the plants growing on tannery sludge dumping sites.the study was undertaken to assess the phytoremediation potential of four plants (sida acuta, ricinus communis, calotropis procera, cassia fistula) growing at a tannery sludge disposal site. results showed that maximum amount of k, fe and ni was associated with residual fraction, whereas, zn, mn, cr, pb, cd and co was found in fe-mn oxide fraction. cu and na were mostly associated with organic matter and carbonate fraction, respectively. the results demonstrated that the levels of accumulation o ...200716973356
effect of cassia fistula linn. leaf extract on diethylnitrosamine induced hepatic injury in rats.the hepatoprotective and antioxidant effect of cassia fistula linn. leaf extract on liver injury induced by diethylnitrosamine (den) was investigated. wistar rats weighing 200+/-10g were administered a single dose of den (200mg/kg b.w., i.p.) and left for 30 days. for hepatoprotective studies, ethanolic leaf extract (ele) of c. fistula linn. (500mg/kg b.w., p.o.) was administered daily for 30 days. ast, alt, alp, ldh, gamma-gt and bilirubin were estimated in serum and liver tissue. lipid peroxid ...200717289008
kinetic studies for ni(ii) biosorption from industrial wastewater by cassia fistula (golden shower) biomass.the present study explores the ability of cassia fistula waste biomass to remove ni(ii) from industrial effluents. c. fistula biomass was found very effective for ni(ii) removal from wastewater of ghee industry (gi), nickel chrome plating industry (ni-cr pi), battery manufacturing industry (bmi), tanner industry: lower heat unit (tilhu), tannery industry: higher heat unit (tihhu), textile industry: dying unit (tidu) and textile industry: finishing unit (tifu). the initial ni(ii) concentration in ...200717289258
colorectal foreign body--a case report.colorectal foreign bodies are frequently encountered with increased incidence of homosexuality and anal auto-erotism. a thirty-five years old unmarried male presented with an incarcerated rectal foreign body, a phallus shaped dried fruit of cassia fistula. it was removed transanally after manipulation at laparotomy. the case is presented here due to its rarity.200617388014
isolation of antileishmanial sterol from the fruits of cassia fistula using bioguided fractionation.natural products represent a rich source of new chemical entities for the development of drugs for neglected diseases. leishmaniasis still afflicts the poorest populations in the world, with 12 million cases worldwide. this work analysed crude extracts and fractions from the fruits of cassia fistula against the most dramatic and fatal disease form of leishmaniasis, the visceral form (vl). hexane extract from the fruits showed significant antileishmanial activity against the promastigote form of ...200717397117
total phenol, antioxidant and free radical scavenging activities of some medicinal plants.phenols, a major group of antioxidant phytochemicals, have profound importance due to their biological and free radical scavenging activities. to identify their potential sources, extracts of some plants were studied for their total phenolic content (tpc), antioxidant (aoa) and free radical scavenging activities (frsa) by different methods at multiple concentrations followed by specific phenolic composition. the amount of tpc varied from 2.8 mg/g (withania somnifera, roots) to 107.8 mg/g (cassia ...200717415953
activity of synergistic combination amoxy-cassia against salmonella.the object of this study was to formulate new, cost effective anti-microbial combination for multi drug resistant (mdr) salmonella enterica serover typhi (sest) based on the synergistic activity of amoxicillin with the aqueous fruit solution of cassia fistula (cff), a medicinal plant found in pakistan which when tested alone have weak antimicrobial activity against blood isolates of mdr sest. mic of mdr sest for amoxicillin and cff alone was 750 microg/ml and 3750 microg/ml. the mic of amoxicill ...200717416570
antibacterial and antifungal activity of cassia fistula l.: an ethnomedicinal plant.hexane, chloroform, ethyl acetate, methanol and water extracts from the flower of cassia fistula (an ethnomedicinal plant) were tested against bacteria and fungi. all the extracts exhibited antibacterial activity against gram-positive organisms with minimum inhibitory concentrations (mic) between 0.078 and 2.5 mg/ml. among the gram-negative bacteria, only pseudomonas aeruginosa was susceptible to the extracts. ethyl acetate crude extract was fractionated using chromatographic techniques. a cryst ...200717532583
ecological niche of cryptococcus neoformans var. grubii and cryptococcus gattii in decaying wood of trunk hollows of living trees in jabalpur city of central india.cryptococcus neoformans var. grubii and c. gattii were repeatedly isolated from decaying wood of trunk hollows in living trees growing in jabalpur city in central india. the isolation of c. gattii has been reported from decayed wood inside trunk hollow of tamarindus indica (15.6%), mangifera indica (2.2%), pithecolobium dulce (12.5%), syzygium cumini (14%), and one from bark of s. cumini. c. n. var. grubii was isolated from decaying wood debris of t. indica (4.4%), m. indica (13.3%), terminalia ...200717661160
genetic diversity in some perennial plant species with-in short distances.distinct morphophysiological variations observed for over 2 years with-in short distances among four perennial plants indicated genetic diversity among the lines growing at three places. the isozyme and sds polyacrylamide gel banding patterns as genetic markers were used to investigate four perennial species, namely dalbergia sissoo roxb., delonix regia (boj.) refin., cassia fistula l. and calotropis procera r. br. plant materials collected from three locations (agra, gwalior and lucknow) differ ...200717717991
biochemical parameters of plants as indicators of air pollution.in the present study species like mangifera indica, linn., cassia fistula, linn., and eucalyptus hybrid were exposed to different air pollution load for short duration (active biomonitoring). variation in biochemical parameters like chlorophyll, protein, soluble sugar free amino acid, ascorbic acid, nitrate reductase, superoxide dismutase and peroxidase in the leaves were found to be pollution load dependent. these variations can be used as indicators of air pollution for early diagnosis of stre ...200717717999
larvicidal and ovicidal activity of cassia fistula linn. leaf extract against filarial and malarial vector mosquitoes.methanolic leaf extract of cassia fistula was tested for larvicidal and ovicidal activity against culex quinquefasciatus and anopheles stephensi. the extract was found to be more lethal to the larvae of a. stephensi than c. quinquefasciatus with lc(50) values of 17.97 and 20.57 mg/l, respectively. mean percent hatchability of the ovicidal activity was observed 120 h after treatment. the percent hatchability was inversely proportional to the concentration of extract and directly proportional to t ...200817989995
modulation of humoral immunity by cassia fistula and amoxy-cassia.immonomodulatory effect of fruit of c fistula, a traditional medicinal plant and its synergistic antimicrobial combination with amoxicillin named amoxy-cassia (patent # 1371240, government of pakistant) studied on humoral immune system of balb/c mice. animal immunized with sheep rbc and treated with c. fistula fruit, amoxycassia, amoxicillin and saline number of activated anti-srbc producing cell in spleen calculated by haemolytic plaque assay. antibody titer in blood was measured by haemaggluti ...200818166514
antiparasitic activity of biochanin a, an isolated isoflavone from fruits of cassia fistula (leguminosae).the fractionation through bioguided antileishmanial activity of the dichloromethane extract of cassia fistula fruits (leguminosae) led to the isolation of the active isoflavone biochanin a, identified by spectroscopic methods. this compound showed 50% effective concentration (ec(50)) value of 18.96 microg/ml against promastigotes of leishmania (l.) chagasi. the cytotoxicity of this substance against peritoneal macrophages resulted in an ec(50) value of 42.58 microg/ml. additionally, biochanin a ...200918810492
protective effect of different parts of cassia fistula on human umbilical vein endothelial cells against glycated protein-induced toxicity in vitro.the protective effect of methanol extracts of cassia fistula (flowers, leaves and bark) was examined in vitro in human umbilical vein endothelial cells (huvec) against toxicity induced by glycated protein (gfbs) in vitro. the experiments consisted of eight groups of huvec with five flasks in each group. group i was treated with 15% fbs, group ii with gfbs (70 microm) alone, and the other six groups were treated with gfbs plus 25 and 50 microg of each of the three types of c. fistula extracts. af ...200819088944
bioefficacy of cassia fistula linn. (leguminosae) leaf extract against chikungunya vector, aedes aegypti (diptera: culicidae).the leaf extract of cassia fistula with different solvens viz, methanol, benzene and acetone were studied for the larvicidal, ovicidal and repellent activity against aedes aegypti. the extract exhibited dose dependent activity and produced significant mortality. the 24 h lc50 concentration of the extract against aedes aegypti were observed at 10.69, 18.27 and 23.95 mg/l respectively. mean percent hatchability of the ovicidal activity was observed 120.00 h after treatment. the percent hatchabilit ...200919499844
ethno-medicinal application of plants in the eastern region of shimoga district, karnataka, india.the present paper aimed to document and study the role of traditional herbal drugs in the treatment of human and veterinary ailments by communities residing in the eastern part of shimoga district of karnataka in india and to determine the consensus of informant's knowledge on different category of ailments and fidelity level of plant species in treating particular disease.200919686831
evaluating the antifertility potential of an aqueous extract from cassia fistula seeds in male rats.cassia fistula suppresses fertility in male rats. withdrawal of extract restored all the altered parameters, including organ weights, fertility, circulatory level of hormones and tissue biochemistry, to control levels after 120 days.201019819443
insulin mimetic impact of catechin isolated from cassia fistula on the glucose oxidation and molecular mechanisms of glucose uptake on streptozotocin-induced diabetic wistar rats.diabetes mellitus is the most common and serious metabolic disorder among people all over the world. many plants have successfully been used to overcome this problem. cassia fistula, an ethnomedicnal plant, is widely used in indian medicine to treat diabetes. methanol extract of stem of plant, reduced the blood glucose levels in streptozotocin-induced diabetic rats. bioassay guided fractionation was followed to isolate catechin from methanol extract. catechin was administered to streptozotocin ( ...201019931438
chromosome number of cassia fistula. 194620280175
screening and partial immunochemical characterization of sulfite oxidase from plant source.sulfite oxidase [so; ec 1.8.3.1] catalyses the physiologically vital oxidation of sulfite to sulfate, the terminal reaction in degradation of sulfur containing amino acids, cysteine and methionine. sulfite oxidase from vertebrate sources is among the best studied molybdenum enzymes. existence of so in plants has been established recently by identification of a cdna from arabidopsis thaliana encoding a functional so. the present study was undertaken to identify herbaceous and woody plants (viz., ...201020358871
heavy metal bioaccumulation in selected medicinal plants collected from khetri copper mines and comparison with those collected from fertile soil in haridwar, india.heavy metal distribution in medicinal plants is gaining importance not only as an alternative medicine, but also for possible concern due to effects of metal toxicity. the present study has been focused on emphasizing the heavy metal status and bioaccumulation factors of v, mn, fe, co, cu, zn, se (essential metals) and cr, ni, cd, as and pb (potentially toxic metals) in medicinal plants grown under two different environmental conditions e.g., near to khetri copper mine and those in fertile soils ...201020390948
antiulcer activity of ethanol leaf extract of cassia fistula.the ethanol leaf extract (ele) of cassia fistula linn. (caesalpinaceae) was evaluated for antiulcer activity against pylorus ligation-induced gastric ulcer. ranitidine (30 mg/kg b.w.) and ele at doses of 250, 500, and 750 mg/kg b.w. were administered orally in different groups of rats (n = 6), 1 h prior to pyloric ligation. four hours after pyloric ligation, the gastric juice was collected for evaluation of various parameters. the antiulcer activity of ele was evidenced by the significant attenu ...201020673173
minimum inhibitory concentrations of medicinal plants used in northern peru as antibacterial remedies.the plant species reported here are traditionally used in northern peru to treat bacterial infections, often addressed by the local healers as "inflammation". the aim of this study was to evaluate the minimum inhibitory concentration (mic) of their antibacterial properties against gram-positive and gram-negative bacteria.201020678568
biochemical changes in plant leaves as a biomarker of pollution due to anthropogenic activity.the air pollution due to anthropogenic activities seriously affected human life, vegetation, and heritage as well. the vegetation cover in and around the city mitigates the air pollution by acting as a sink for pollution. an attempt was made to evaluate biochemical changes occurred in four selected plant species, namely azadirachta indica, mangifera indica, delonix regia, and cassia fistula of residential, commercial, and industrial areas of nagpur city in india. it was observed that the correla ...201120721619
a review of the efficacy of traditional iranian medicine for inflammatory bowel disease.the etiology of inflammatory bowel disease (ibd) is not yet known, but many factors such as defects in the immune system, oxidative stress, microbial content in the gastrointestinal tract, nuclear factor (nf)-κb, nitric oxide (no), cyclooxygenase-2 (cox-2), and leukotriene b4 (lb4) are thought to play a role in its pathogenesis. in traditional iranian medicine (tim), several medicinal plants are thought to be effective for the treatment of ibd. in this study, information on all of these remedies ...201020857519
protective effect of cassia fistula fruit extract against bromobenzene-induced liver injury in mice.in the present study, hepatoprotective effect of cassia fistula fruit extract was investigated in mice. animals were divided into six groups receiving normal saline (1), bromobenzene (460 mg/kg) alone (2) and together with increasing doses (200, 400, 600, 800 mg/kg) of a crude hydro-alcoholic extract of cassia fistula fruit (3-6, respectively). all administrations were carried out orally, daily, for 10 days. on the 11th day, animals were sacrificed. serum activities of aspartate aminotransferase ...201020930029
protective effect of cassia fistula linn. on diethylnitrosamine induced hepatocellular damage and oxidative stress in ethanol pretreated rats.diethylnitrosamine (den), found in many commonly consumed foods, is widely reported to induce cancer in animals and humans. the aim of the present study was to investigate the hepatoprotective and antioxidant activities of the leaf extract of the medicinal plant cassia fistula linn. against diethylnitrosamine induced liver injury in ethanol pretreated rats. albino wistar rats, pretreated with ethanol for 15 days, were administered a single dose of den. thirty days after den administration, hepat ...201021157638
study of the synergistic anti-inflammatory activity of solanum xanthocarpum schrad and wendl and cassia fistula linn.nonsteroidal and steroidal drugs are generally used as a part of drug therapy in inflammation. however, these drugs have severe side-effects like nausea and vomiting. therefore, there is a need to identify anti-inflammatory compounds that will be effective with a better safety profile. solanum xanthocarpum schrad and wendl and cassia fistula linn has many therapeutic uses mentioned in ayurveda and therefore we aimed to study its anti-inflammatory activity both alone and in combination.201021170209
protective effect of cassia fistula fruit extract on bromobenzene-induced nephrotoxicity in mice.the efficacy of a crude hydro-alcoholic extract of cassia fistula (golden shower tree) fruit to protect the kidney against bromobenzene-induced toxicity was studied. negative control mice received normal saline; positive control mice were given 460 mg/kg of bromobenzene; cassia fistula treated mice received 200, 400, 600 and 800 mg/kg of cassia fistula fruit extract followed by 460 mg/kg bromobenzene (daily by oral gavage for 10 days). on the 11th day, the mice were sacrificed, blood samples wer ...201121247991
aldose reductase inhibitory, anti-cataract and antioxidant potential of selected medicinal plants from the marathwada region, india.the water, ethanol and chloroform extracts of selected plants such as adhatoda vasica (l.) (acanthaceae), caesalpinia bonduc (l.), cassia fistula (l.) (caesalpiniaceae) and biophytum sensitivum (l.) (oxalidaceae) were evaluated for rat lens aldose reductase inhibitory (rlar) potential, anti-cataract and antioxidant activities. all the samples inhibited the aldose reductase considerably and exhibited anti-cataract activity, while c. fistula (ic(50), 0.154 mg ml(-1)) showed significant rlar inhibi ...201121462076
anticandidal activity of cassia fistula and its effect on ergosterol biosynthesis.context: cassia fistula linn. (caesalpiniaceae) has been used in folk medicine. anthraquinone derivative rhein having antimicrobial properties is actively present in c. fistula fruit. although, as yet there has been no study of its anticandidal potential. objective: the present study was conducted to determine the phytochemical composition of fruit pulp and seed extract and their effect on candida albicans atcc 10261, candida glabrata atcc 90030 and candida tropicalis atcc 750, respectively. mat ...201121591840
acute oral toxicity of methanolic seed extract of cassia fistula in mice.cassia fistula is widely used in traditional medicine to treat various types of ailments. the evaluation of toxic properties of c. fistula is crucial when considering public health protection because exposure to plant extracts can result in undesirable effects on consumers. hence, in this study the acute oral toxicity of c. fistula seeds extract was investigated in mice.201121701437
evaluation of cytotoxicity and genotoxicity of some philippine medicinal plants.the genotoxicity and toxicity of ethnomedicinal philippine plants, which include cassia fistula, derris elliptica, ficus elastica, gliciridia sepium, michelia alba, morus alba, pogostemon cablin and ricinus communis, were tested using the vitotox assay. the plants are used traditionally to treat several disorders like diabetes, weakness, menorrhagia, headache, toothache and rheumatism. the dried leaves were homogenized for overnight soaking in methanol at room temperature. the resulting alcoholi ...201121716927
antioxidant activity of phenolic and flavonoid compounds in some medicinal plants of india.in this study, total phenolics, flavonoids and vitamin c content vis-a-vis antioxidant activities were assayed in leaves and stem bark of azadirachta indica, butea monosperma, cassia fistula, mangifera indica, syzygium cumini and tamarindus indica using the 2,2-diphenyl-1-picrylhydrazyl (dpph) and superoxide radical scavenging method. the dpph radical scavenging activity positively correlated with the total phenolic content in both stem bark and leaf. superoxide radical scavenging activity incre ...201121726132
a new minor dimmeric ester from seeds of cassia fistula l. (leguminosae).bioactivity-guided fractionation of n-hexane phase from meoh extract of the seeds of cassia fistula l. (leguminosae) yielded two bioactive substances against cladosporium cladosporioides and c. sphaerospermum. after spectroscopic analysis, these compounds were characterised as the known benzyl 2-hydroxy-3,6-dimethoxybenzoate and its dimer dibenzyl 2,2'-dihydroxy-3,6,3?,6?-tetramethoxy-biphenyl-1,1'-dicarboxylate, which showed a new structural arrangement.201121756186
bioassay-directed isolation of active compounds with antiyeast activity from a cassia fistula seed extract.cassia fistula l belongs to the family leguminosae, and it is one of the most popular herbal products in tropical countries. c. fistula seeds have been used as a herbal medicine and have pharmacological activity which includes anti-bacterial, anti-fungal, and antioxidant properties. the goal of this study was to identify compounds from c. fistula seeds which are responsible for anti-candida albicans activity using bioassay-directed isolation.201121894090
role of rasayana in cure and prevention of recurrence of vicharchika (eczema).generally, skin diseases run a chronic course and the recurrence is very common. mandip and chandola (2009) reported that shirishadi decoction administered orally and simultaneously snuhyadi lepa applied externally to the patients of vicharchika (eczema) provided complete remission to 18.2% patients, marked improvement to 42.4% patients and moderate improvement to 36.4% patients but the recurrence rate was very high i.e. 80%. charaka, in the context of the treatment of apasmara mentions that in ...201022131682
Antibacterial activities and phytochemical analysis of Cassia fistula (Linn.) leaf.Cassia fistula Linn. which belongs to family Leguminosae is a medium-sized tree and its different parts are used in ayurvedic medicine as well as home remedies for common ailments. Sequential extraction was carried out using solvents viz. petroleum ether, chloroform, ethanol, methanol and water from leaf of the plant were investigated for preliminary phytochemical and antibacterial property. Results of the study showed that all the extracts had good inhibitory activity against Gram-positive test ...201122171295
Antibacterial and antifungal activities from leaf extracts of Cassia fistula l.: An ethnomedicinal plant.This study was carried out with an objective to investigate the antibacterial and antifungal potentials of leaves of Cassia fistula Linn. The aim of the study is to assess the antimicrobial activity and to determine the zone of inhibition of extracts on some bacterial and fungal strains. In the present study, the microbial activity of hydroalcohol extracts of leaves of Cassia fistula Linn. (an ethnomedicinal plant) was evaluated for potential antimicrobial activity against medically important ba ...201122171301
optimization of an aqueous tablet-coating process containing carboxymethylated cassia fistula gum.the present investigation was aimed at developing and optimizing a simple aqueous tablet-coating formulation and its process. 5-fluorouracil (5-fu) was used to ascertain the relative lipophilic/hydrophilic behavior of the coating system. optimization was performed by evaluating the adhesive force strength and cohesive force strength of the tablet coat using a texture analyzer. the in vitro release of 5-fu was found to decrease with an increase in (tablet surface-coat) adhesive force strength. th ...201222362140
biochemical analysis of cassia fistula aqueous extract and phytochemically synthesized gold nanoparticles as hypoglycemic treatment for diabetes mellitus.cassia fistula stem bark was used for the preparation of aqueous extract and synthesis of gold nanoparticles to evaluate the hypoglycemic effects of the plant. the synthesized gold nanoparticles were characterized by ultraviolet-visible spectroscopy for their absorbance pattern, fourier transform infrared spectroscopy to identify possible functional groups, and scanning electron microscopy to determine the size of the nanoparticles. the present investigation reports the efficacy of the gold nano ...201222419867
bioactivity of phytochemicals in some lesser-known plants and their effects and potential applications in livestock and aquaculture production systems.livestock and aquaculture production is under political and social pressure, especially in the european union (eu), to decrease pollution and environmental damage arising due to animal agriculture. the eu has banned the use of antibiotics and other chemicals, which have been shown to be effective in promoting growth and reducing environment pollutants because of the risk caused to humans by chemical residues in food and by antibiotic resistance being passed on to human pathogens. as a result of ...200722444893
chromatographic studies on a herb decoction.argwadhadhi kwatham is a compound preparation of 3 single drugs viz cassia fistula l. azadirachta indica a., tinospora cordifolia l. literature survey show tat all3 ingredients are very effective for skin diseases. kahayams prepared individually with these 3 drugs was found to be more effective for skin dideases. this paper deals with a comparative study of the chemical constituents present in aragwadhadhi kwatham and the individual kwathams, all the four kwarham were chemically analysed t.l.c. ...199822556839
role of aragvadhadi sutra in the management of fistula -in-ano.traditional medicine has its own importance for the treatment of various medical and surgical diseases irrespective of tremendous development of modern medicine. there are number of diseases were after repeated surgery. fistula-in ano is one such condition which is prone to recurrence even after repeated surgery and can be effectively treated by ayurvedic medicines. an extensive work has been done on the treatment of bhagandara by kshara sutra exploring various aspects of the problem and finding ...200022556930
efficacy of some botanical extracts against trogoderma granarium in wheat grains with toxicity evaluation.in an attempt to find alternative control methods for stored products insects, extracts of seven plant species (cassia senna, caesalpinia gilliesii, thespesia populnea var. acutiloba, chrysanthemum frutescens, euonymus japonicus, bauhinia purpurea, and cassia fistula) were evaluated under laboratory conditions for their ability to protect wheat (triticum spp.) grains against trogoderma granarium insect. moreover, gas chromatography-mass spectrometry (gc-ms) analysis was carried to identify the c ...201222606054
anti-proliferative activities on hela cancer cell line of thai medicinal plant recipes selected from manosroi ii database.the thai/lanna medicinal plant recipe database "manosroi ii" contained the medicinal plant recipes of all regions in thailand for the treatment of various diseases including anti-cancer medicinal plant recipes.201222626926
in vitro, in situ and in vivo studies on the anticandidal activity of cassia fistula seed extract.cassia fistula seeds have many therapeutic uses in traditional medicine practice. the present investigation was undertaken to demonstrate the anticandidal activity of the c. fistula seed extract at ultra-structural level through transmission electron microscope (tem) and scanning electron microscope (sem) observations. the effect of seed extract on the growth profile of the candida albicans was examined via time-kill assays and in vivo efficacy of the extract was tested in an animal model. in ad ...201222678414
antibacterial activity of fistulin: a protease inhibitor purified from the leaves of cassia fistula.plant protease inhibitors (ppis) are one of the important components of a plant's defense machinery. ppis are active against the insects and microbes which invade the plant. cassia species possess anti-insecticidal and antimicrobial properties and this study was aimed at investigating the antibacterial efficacy of a ppi present in the leaves of cassia fistula. a ppi, fistulin, was isolated from the leaves of c. fistula and purified by gel filtration chromatography. the antibacterial activity of ...201222779011
airborne load of cassia pollen in west bengal, eastern india: its atmospheric variation and health impact.a burkard personal volumetric sampler was used at sriniketan, a town about 150 km northwest of calcutta, in the state of west bengal, in eastern india to record the frequency of three common airborne cassia pollen types, cassia tora, cassia occidentalis, and cassia fistula for two consecutive years (2004-2006). correlation was made between the meteorological factors and the pollen concentration in the atmosphere. the study reports cassia pollinosis by in vivo skin prick test in respiratory aller ...201322810379
in vitro antibacterial and antifungal activities of cassia fistula linn. fruit pulp extracts.aim of the study is to assess the antimicrobial activity cassia fistula fruit pulp extracts on some bacterial and fungal strains. hydro alcohol and chloroform extracts of cassia fistula fruit pulp were evaluated for the potential antimicrobial activity. the antimicrobial activity was determined in both the extracts using the agar disc diffusion method. extracts were effective on tested microorganisms. the antibacterial and antifungal activities of solvent extracts (5, 25, 50, 100, 250 μg/ml) of ...201223049197
antiplasmodial activity of the ethnobotanical plant cassia fistula.in our ongoing investigation of new compounds with activity against malaria parasites, we tested the in vitro antiplasmodial activity of fractions and purified compounds from cassia fistula l., a plant traditionally used by native populations of tanzania, zimbabwe, mozambique and brazil to treat malaria or symptoms associated with this disease. crude extracts from leaves, bark and fruits were tested for their antiplasmodial activity against the chloroquine-sensitive strain of plasmodium falcipar ...201223156984
cytokinin changes in embryo and endosperm of cassia fistula during fruit growth.cytokinin activity was determined in embryo and endosperm tissues from 30-day (stage 1), 55-jay (stage 2), and 80-day (stage 3) old fruits of cassia fistual. high cytokinin activity was associated with stage 1 and the least in stage 3. this indicated that the cytokinins disappeared during the course of seed development. sephadex lh-20 column chromatography with 35% ethanol indicated the presence of cytokinins coeluting with zeatin glucoside, zeatin riboside, and zeatin. qualitatively the cytokin ...198423195505
the effect of cassia fistula emulsion on pediatric functional constipation in comparison with mineral oil: a randomized, clinical trial. 201223351337
composition of cassia fistula oil and its antifungal activity by disrupting ergosterol biosynthesis.cassia fistula oil was investigated for antifungal activities against standard and clinical isolates of candida species. gas chromatography coupled with mass spectrometric (gc-ms) analysis of c. fistula oil revealed the presence of antimicrobial compounds like beta-sitosterol, stigmasterol, ergosterol, betulinic acid, lupeol, fucosterol, alpha-amyrin and friedelin. the minimum inhibitory concentration (mic) of the pulp and seed oils ranged between 250-300 and 350-500 microg/ml respectively. both ...201323513744
a new natural naphtho[1,2-b]furan from the leaves of cassia fistula.a new naphtho[1,2-b]furan, 2,9-dihydroxy-7-methoxy-4-methylnaphtha[1,2-b]furan-3(2h)-one (1), along with 10 known compounds vanillic acid (2), naringenin (3), glyceryl-1-tetracosanoate (4), moracin j (5), 1,3,8-trihydroxyanthraquinone (6), esculetin (7), mauritianin (8), kaempferol 3-neohesperidoside (9), β-sitosterol (10), and β-daucosterol (11), was isolated from the leaves of cassia fistula. the structure of the new compound was determined by nmr and x-ray analysis. compounds 1, 3, 5-9 were i ...201323822190
acaricidal effect of cassia fistula linn. leaf ethanolic extract against rhipicephlaus (boophilus) annulatus.the present study evaluates the acaricidal properties of crude ethanolic extract of cassia fistula leaves for controlling rhipicephalus (boophilus) annulatus based on adult immersion test (ait). the percentage of adult mortality, inhibition of fecundity and hatching of ova laid were studied at different concentrations of the extract ranging from 50 to 100 mg / ml. the results were compared using one-way anova. the extract produced complete inhibition of hatching of eggs at concentrations above 8 ...201323959488
antifeedant and larvicidal activities of rhein isolated from the flowers of cassia fistula l.antifeedant and larvicidal activities of rhein (1,8-dihydroxyanthraquinone-3-carboxylic acid) isolated from the ethyl acetate extract of cassia fistula flower were studied against lepidopteron pests spodoptera litura and helicoverpa armigera. significant antifeedant activity was observed against h. armigera (76.13%) at 1000 ppm concentration. rhein exhibited larvicidal activity against h. armigera (67.5), s. litura (36.25%) and the lc50 values was 606.50 ppm for h. armigera and 1192.55 ppm for s ...201123961115
ethnomedicinal plants used for treating epilepsy by indigenous communities of sub-himalayan region of uttarakhand, india.although many plants are claimed to possess anticonvulsant/antiepileptic (ac/ae) properties, but there is very little information available about plants used by various ethnic communities in different parts of india to treat epilepsy, one of the most common disorders of central nervous system (cns); this communication provides significant ethnomedicinal information on the plants used by indigenous communities: bhoxa, tharu and nomadic gujjars of sub-himalayan region, uttarakhand, india to treat ...201324029249
pharmacological potentials of cassia auriculata and cassia fistula plants: a review.people are using herbal medicines from centuries for safety, efficacy, cultural acceptability and lesser side effects. plant and plant products have utilized with varying success to cure and prevent diseases throughout history. therapeutically interesting and important drugs can be developed from plant sources which are used in traditional systems of medicines. indian traditional system of medicine is based on empirical knowledge of observations and the experience over millennia and more than 50 ...201224163950
hplc quantitative analysis of rhein and antidermatophytic activity of cassia fistula pod pulp extracts of various storage conditions.cassia fistula is well known for its laxative and antifungal properties due to anthraquinone compounds in the pods. this study quantitatively analyzed rhein in the c. fistula pod pulp decoction extracts kept under various storage conditions using hplc. the antifungal activity of the extracts and their hydrolyzed mixture was also evaluated against dermatophytes. the contents of rhein in all stored decoction extracts remained more than 95% (95.69-100.66%) of the initial amount (0.0823 ± 0.001% w/w ...201324171175
differentiation in explants from mature leguminous trees.stem and petiole explants, obtained from mature trees, ofalbizzia lebbeck,cassia fistula andc.siamea callused and differentiated shoot-buds and later shoots on b5 medium supplemented with either 0.5 mg/l iaa + 1 mg/l bap or bm + 2 mg/l naa + 0.5 mg/l bap. the stem explants were more responsive than the petiole explants. ina.lebbeck, the iaa substituted medium favoured differentiation from both types of explants. however, inc.fistula, the type of explants rather than the medium composition had an ...199024226284
in vitro antioxidant activity of hydro alcoholic extract from the fruit pulp of cassia fistula linn.the present study is aimed to investigate antioxidant activity of the extracts of cassia fistula linn. (leguminosae) fruit pulp. cassia fistula linn., a indian laburnum, is widely cultivated in various countries and different continents including asia, mauritius, south africa, mexico, china, west indies, east africa and brazil as an ornamental tree for its beautiful bunches of yellow flowers and also used in traditional medicine for several indications. the primary phytochemical study and in vit ...201324250133
whitening efficacy of plant extracts including hippophae rhamnoides and cassia fistula extracts on the skin of asian patients with melasma.melasma/hyperpigmentation and solar damage of the skin remains a difficult problem to treat. various types of whitening agents are used to treat hyperpigmentation. a change has been observed recently to use plant extracts as skin whitening agents.201324278079
biochemical evaluation of the hypoglycemic effects of extract and fraction of cassia fistula linn. in alloxan-induced diabetic rats.various extracts of flowers of cassia fistula linn (leguminosae) such as petroleum ether (60-80°), chloroform, acetone, ethanol, aqueous, and crude aqueous extracts and two fractions of ethanol extract were tested for antihyperglycemic activity in glucose-overloaded hyperglycemic rats. the effective antihyperglycemic extracts and fraction were tested for their hypoglycemic activity at two dose levels, 200 and 400 mg/kg, respectively. to confirm their utility in higher models, the effective extra ...201324302797
effect of tamarindus indica linn. and cassia fistula linn. stem bark extracts on oxidative stress and diabetic conditions.tamarindus indica and cassia fistula are traditionally important medicinal plants. stem barks of these plants have not been much explored for their potential hypoglycemic and oxidative stress conditions. the main aim of present study was to evaluate antidiabetic activity along with renal complications and antioxidant potential of alcoholic extracts of stem barks of these plants. alcoholic extracts of stem barks of tamarindus indica and cassia fistula were evaluated for anti-hyperglycemic effect ...201624383324
plants used for treatment of dysentery and diarrhoea by the bhoxa community of district dehradun, uttarakhand, india.dysentery and diarrhoea are major causes of morbidity and mortality in rural communities of developing world. the bhoxa community is an important primitive indigenous community of uttarakhand, india. in this paper we have tried to scientifically enumerate ethnomedicinal plants and herbal preparations used by bhoxa community to treat dysentery and diarrhoea, and discuss their antidiarrhoeal properties in the light of previous ethnomedicinal, pharmacological, microbiological and phytochemical stud ...201324432368
plants used for treatment of dysentery and diarrhoea by the bhoxa community of district dehradun, uttarakhand, india.dysentery and diarrhoea are major causes of morbidity and mortality in rural communities of developing world. the bhoxa community is an important primitive indigenous community of uttarakhand, india. in this paper we have tried to scientifically enumerate ethnomedicinal plants and herbal preparations used by bhoxa community to treat dysentery and diarrhoea, and discuss their antidiarrhoeal properties in the light of previous ethnomedicinal, pharmacological, microbiological and phytochemical stud ...201324513640
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