Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| genetic characterization of selected parasites from people with histories of gastrointestinal disorders using a mutation scanning-coupled approach. | a sscp analysis and targeted sequencing approach was used for the genetic characterization of some major pathogens from a cohort of 227 people with histories of gastrointestinal disorders. genomic dnas from fecal samples were subjected to pcr-amplification of regions in the glycoprotein (gp60) or triose phosphate isomerase (tpi) gene, or the second internal transcribed spacer of nuclear ribosomal dna (its-2). cryptosporidium, giardia, and strongylid nematodes were detected in 94, 132 and 12 samp ... | 2013 | 23592267 |
| prevalence of intestinal parasitic infections and associated risk factors among kigali institute of education students in kigali, rwanda. | intestinal parasitic infections (ipis) are a significant public health problem in sub- saharan africa (ssa) and rwanda is not spared. while eradication programs towards preschool-aged and school-aged children are undertaken, important gaps regarding ipis among students attending tertiary learning institutions remain. the aim of this study was to determine the prevalence of ipis and associated risk factors among kigali institute of education (kie) students who attended its medical clinic for stoo ... | 2013 | 24522143 |
| [a case of lung paragonimiasis superinfection with hookworm presenting difficulty in discrimination]. | a 40-year-old woman, who was born in thailand and moved to japan 20 years previously, was admitted to our university hospital because of eosinophilia and abnormal chest radiography findings over a 6-month period. the chest ct showed multiple cavitary nodules in the subpleural area and a tubular structure that extended from each cavity to the pleura. immunological examination revealed an elevation of antibody titers against ancylostoma duodenale, paragonimiasis miyazakii and paragonimiasis wester ... | 2013 | 24483024 |
| prevalence of ancylostomiasis in people living in slum area, philhousepet of eluru, west godavari district (andhra pradesh). | hookworm infection was found in the slum area of eluru, west godavari district, a.p. which has scheduled caste population. infection is related to different climatic conditions and socio-economic status of the population. the inhabitants are coolies in agricultural fields and household workers with a poor level of hygiene and sanitation. all the infected positive cases showed ancylostoma duodenale infection. the prevalence of hookworm infection was 15.6, 17.9 and 14 % in children, 23.5, 27.9 and ... | 2013 | 24431537 |
| a case of parasite invasion of the intestinal tract: a missed diagnosis in irritable bowel syndrome. | irritable bowel syndrome (ibs) is a gastrointestinal disorder characterized by chronic abdominal pain and altered bowel habits in the absence of any organic cause. as the clinical manifestations are very diverse and associated with nonspecific symptoms, research seeking to identify organic causes to rule out ibs and to enable differential diagnosis is required. a 24-year-old man was referred to our hospital for specialized management of ibs. he had a 7-month history of intermittent epigastric an ... | 2013 | 24340264 |
| impact of helminth diagnostic test performance on estimation of risk factors and outcomes in hiv-positive adults. | traditional methods using microscopy for the detection of helminth infections have limited sensitivity. polymerase chain reaction (pcr) assays enhance detection of helminths, particularly low burden infections. however, differences in test performance may modify the ability to detect associations between helminth infection, risk factors, and sequelae. we compared these associations using microscopy and pcr. | 2013 | 24324729 |
| baboons as potential reservoirs of zoonotic gastrointestinal parasite infections at yankari national park, nigeria. | zoonoses pose a risk to public health. | 2013 | 24235920 |
| molecular detection of ancylostoma duodenale, ancylostoma ceylanicum, and necator americanus in humans in northeastern and southern thailand. | the 2 principal species of hookworms infecting humans are necator americanus and ancylostoma duodenale. case studies on zoonotic hookworm infections with ancylostoma ceylanicum and/or ancylostoma caninum are known mainly from asian countries. of these 2 zoonotic species, only a. ceylanicum can develop to adulthood in humans. in the present study, we report a molecular-based survey of human hookworm infections present in southern and northeastern thailand. thirty larval hookworm samples were obta ... | 2013 | 24516284 |
| parasitic diseases of the pleura. | parasitic infections are prevalent in certain parts of the world and may cause pleural involvement, which often goes unrecognized. common parasites involving the pleura include entamoeba histolytica, echinococcus granulosus and paragonimus westermani. amebiasis can cause empyema with "anchovy sauce" pus, reactive pleural effusions and bronchopleural fistula with hydropneumothorax. echinococcosis may result in pleural thickening, pneumothorax, secondary pleural hydatidosis and pleural effusions. ... | 2013 | 22990049 |
| geohelminths: public health significance. | the worldwide prevalence of geohelminths and their unique place in evolutionary biology have attracted research focus. these major soil-transmitted intestinal nematodes that cause human diseases are the nematode roundworm (ascaris lumbricoides), the whipworm (trichuris trichiura) and the two hookworms (ancylostoma duodenale and necator americanus), often collectively referred as geohelminths. studies of geohelminthiasis in poorly nourished children in developing regions report that geohelminths ... | 2014 | 24423707 |
| controlling soil-transmitted helminths: time to think inside the box? | soil-transmitted helminths (sth) refer to several parasitic nematode species that infect over 1 billion people worldwide. infections with ascaris lumbricoides , trichuris trichiura , and the hookworms necator americanus and ancylostoma duodenale cause significant morbidity in more than 450 million people, primarily children and pregnant women, resulting in over 39 million disability-adjusted life years lost. considerable effort and resources have been, and continue to be, spent on top-down, medi ... | 2014 | 24393037 |
| helminths and human ancestral immune ecology: what is the evidence for high helminth loads among foragers? | recent theories of human immune ecology have invoked high helminth loads as an important selection factor among early humans. however, few studies have assessed this assumption among extant human foragers. | 2014 | 24469911 |
| current status of human hookworm infections, ascariasis, trichuriasis, schistosomiasis mekongi and other trematodiases in lao people's democratic republic. | soil-transmitted helminth (sth) infections, and schistosomiasis and other trematodiases often have a high prevalence in developing countries. here, we present updated information on the prevalence of these parasites in the lao people's democratic republic (lao pdr) in 2012, arising from the annual national helminthiasis survey. fecal specimens were collected from 8,610 inhabitants of 12 provinces and one municipality (bokeo, houaphan, luang namtha, luang prabang, oudomxay, and phongsaly province ... | 2014 | 24515942 |
| prevalence and risk factors of soil-transmitted helminth infection in nepal. | the purpose of this study is to evaluate the prevalence and intensity and examine the risk factors of soil transmitted helminth (sth; i.e., roundworm [ascaris lumbricoides], hookworms [ancylostoma duodenale and necator americanus], and whipworm [trichuris trichiura]) infections in nepal. | 2014 | 24488979 |
| prevalence of intestinal parasites and its impact on nutritional status among preschool children living in damanhur city, el-behera governorate, egypt. | this cross sectional study was done in damanhur city, the capital of el-behera governorate to detect the prevalence of intestinal parasitic infection among preschool aged children and to find out its effect on their nutritional status. five-hundreds children aged between 2-6 years were enrolled; a detailed questionnaire, complete clinical and anthropometric assessment as well as complete stool analysis and blood picture were done. the study revealed that 51.8% preschool children were infected; c ... | 2014 | 25597166 |
| an unusual cause of chronic diarrhoea. | we report a patient presenting with chronic diarrhoea of unidentified etiology. laboratory results showed microcytic anemia, peripheral eosinophilia with negative results of stool sample smears and stool concentration technique. ancylostoma duodenale was found in the caecum and terminal ileum during colonoscopy. the patient was treated with a 3-day course of 400 mg albendazole and iron supplement. the diarrhoea disappeared shortly after treatment. physicians particularly in tropical areas should ... | 2014 | 24862060 |
| overt small-intestine bleeding caused by ancylostoma duodenale. | 2014 | 24745772 | |
| water, sanitation, hygiene, and soil-transmitted helminth infection: a systematic review and meta-analysis. | preventive chemotherapy represents a powerful but short-term control strategy for soil-transmitted helminthiasis. since humans are often re-infected rapidly, long-term solutions require improvements in water, sanitation, and hygiene (wash). the purpose of this study was to quantitatively summarize the relationship between wash access or practices and soil-transmitted helminth (sth) infection. | 2014 | 24667810 |
| influence of physico-chemistry and mineralogy on the occurrence of geohelminths in geophagic soils from selected communities in the eastern cape, south africa, and their possible implication on human health. | geophagic soils from selected communities in eastern cape, south africa were characterised to determine their properties and geohelminth content. the soils were coarse-textured with cation exchange capacity values ranging from 6.35 to 18.94 cmol (+)/kg. quartz was the dominant mineral in the samples with sio2, al2o3, and fe2o3(t) having the highest concentrations among major element oxides. the soil properties, mineralogical composition, and low amounts of particle binding substances may favour ... | 2014 | 23574040 |
| identification of ancylostoma ceylanicum in children from a tribal community in tamil nadu, india using a semi-nested pcr-rflp tool. | it is generally assumed that hookworm infections in humans are caused by necator americanus and ancylostoma duodenale. however, previous studies have also reported the presence of the animal hookworm a. ceylanicum in human stools. | 2015 | 25618132 |
| parasitic infections: is male and female difference for anemia and growth retardation evident? | parasitoses are the commonest health problem among school age clildren, which impair children's growth and development and causing anemia. to detect the role of parasitic infections and both anemia and growth affection, on one hand, and if so the common complications among males and females on the other hand, a cross sectional descriptive study was carried out among the outpatient attended the pediatrics clinic, al-fayoum university's hospitals. a total of 314 children aged from 1 to 13 years we ... | 2015 | 26939224 |
| development and evaluation of a loop mediated isothermal amplification (lamp) technique for the detection of hookworm (necator americanus) infection in fecal samples. | hookworm infection is a major concern in sub-saharan africa, particularly in children and pregnant women. necator americanus and ancylostoma duodenale are responsible for this condition. hookworm disease is one of the neglected tropical diseases (ntds) that are targeted for elimination through global mass chemotherapy. to support this there is a need for reliable diagnostic tools. the conventional diagnostic test, kato-katz that is based on microscopic detection of parasite ova in faecal samples ... | 2015 | 26546069 |
| identification of human intestinal parasites affecting an asymptomatic peri-urban argentinian population using multi-parallel quantitative real-time polymerase chain reaction. | in resource-limited countries, stool microscopy is the diagnostic test of choice for intestinal parasites (soil-transmitted helminths and/or intestinal protozoa). however, sensitivity and specificity is low. improved diagnosis of intestinal parasites is especially important for accurate measurements of prevalence and intensity of infections in endemic areas. | 2015 | 26183074 |
| soil-transmitted helminths in southwestern china: a cross-sectional study of links to cognitive ability, nutrition, and school performance among children. | empirical evidence suggests that the prevalence of soil-transmitted helminth (sth) infections in remote and poor rural areas is still high among children, the most vulnerable to infection. there is concern that sth infections may detrimentally affect children's healthy development, including their cognitive ability, nutritional status, and school performance. medical studies have not yet identified the exact nature of the impact sth infections have on children. the objective of this study is to ... | 2015 | 26110518 |
| [a case of ancylostoma duodenale infection in rectum detected by colonoscopy]. | 2015 | 26080535 | |
| infection with soil-transmitted helminths is associated with increased insulin sensitivity. | given that helminth infections have been shown to improve insulin sensitivity in animal studies, which may be explained by beneficial effects on energy balance or by a shift in the immune system to an anti-inflammatory profile, we investigated whether soil-transmitted helminth (sth)-infected subjects are more insulin sensitive than sth-uninfected subjects. | 2015 | 26061042 |
| comparison of concentration methods for rapid detection of hookworm ova in wastewater matrices using quantitative pcr. | hookworm infection contributes around 700 million infections worldwide especially in developing nations due to increased use of wastewater for crop production. the effective recovery of hookworm ova from wastewater matrices is difficult due to their low concentrations and heterogeneous distribution. in this study, we compared the recovery rates of (i) four rapid hookworm ova concentration methods from municipal wastewater, and (ii) two concentration methods from sludge samples. ancylostoma canin ... | 2015 | 26358269 |
| rapid concentration and sensitive detection of hookworm ova from wastewater matrices using a real-time pcr method. | the risk of human hookworm infections from land application of wastewater matrices could be high in regions with high hookworm prevalence. a rapid, sensitive and specific hookworm detection method from wastewater matrices is required in order to assess human health risks. currently available methods used to identify hookworm ova to the species level are time consuming and lack accuracy. in this study, a real-time pcr method was developed for the rapid, sensitive and specific detection of canine ... | 2015 | 26297680 |
| immune polarization by hookworms: taking cues from t helper type 2, type 2 innate lymphoid cells and alternatively activated macrophages. | cellular and molecular investigation of parasitic helminth infections has greatly accelerated the understanding of type 2 immune responses. however, there remains considerable debate regarding the specific leucocytes that kill parasites and whether these mechanisms are distinct from those responsible for tissue repair. herein, we chronicle discoveries over the past decade highlighting current paradigms in type 2 immunity with a particular emphasis upon how cd4(+) t helper type 2 cells, type 2 in ... | 2016 | 26928141 |
| prevalence of intestinal parasite infections among patients in local public hospitals of hail, northwestern saudi arabia. | to evaluate the prevalence of intestinal parasites among patients in hail, northwestern saudi arabia. | 2016 | 26851785 |
| multi-parallel qpcr provides increased sensitivity and diagnostic breadth for gastrointestinal parasites of humans: field-based inferences on the impact of mass deworming. | although chronic morbidity in humans from soil transmitted helminth (sth) infections can be reduced by anthelmintic treatment, inconsistent diagnostic tools make it difficult to reliably measure the impact of deworming programs and often miss light helminth infections. | 2016 | 26813411 |
| epidemiological surveys of, and research on, soil-transmitted helminths in southeast asia: a systematic review. | soil-transmitted helminth (sth) infections of humans fall within the world health organization's (who) grouping termed the neglected tropical diseases (ntds). it is estimated that they affect approximately 1.4 billion people worldwide. a significant proportion of these infections are in the population of southeast asia. this review analyses published data on sth prevalence and intensity in southeast asia over the time period of 1900 to the present to describe age related patterns in these epidem ... | 2016 | 26813007 |
| detection of intestinal parasites by use of the cuvette-based automated microscopy analyser sedimax(®). | microscopy is the reference method for intestinal parasite identification. the cuvette-based automated microscopy analyser, sedimax 1, provides 15 digital images of each sediment sample. in this study, we have evaluated this fully automated instrument for detection of enteric parasites, helminths and protozoa. a total of 700 consecutively preserved samples consisting of 60 positive samples (50 protozoa, ten helminths) and 640 negative samples were analysed. operators were blinded to each others' ... | 2016 | 26679923 |
| molecular identification of hookworm isolates in humans, dogs and soil in a tribal area in tamil nadu, india. | hookworms (necator americanus and ancylostoma duodenale) remain a major public health problem worldwide. infections with hookworms (e.g., a. caninum, a. ceylanicum and a. braziliense) are also prevalent in dogs, but the role of dogs as a reservoir for zoonotic hookworm infections in humans needs to be further explored. | 2016 | 27486798 |
| molecular diagnostics for soil-transmitted helminths. | historically, the diagnosis of soil-transmitted helminths (sths) (e.g., strongyloides stercoralis, trichuris trichiura, ancylostoma duodenale, necator americanus, and ascaris lumbricoides) has relied on often-insensitive microscopy techniques. over the past several years, there has been an effort to use molecular diagnostics, particularly quantitative polymerase chain reaction (qpcr), to detect intestinal pathogens. while some platforms have been approved by regulatory bodies (e.g., food and dru ... | 2016 | 27481053 |
| mating ancylostoma duodenale under magnifying endoscopy. | 2016 | 27449192 | |
| improved pcr-based detection of soil transmitted helminth infections using a next-generation sequencing approach to assay design. | the soil transmitted helminths are a group of parasitic worms responsible for extensive morbidity in many of the world's most economically depressed locations. with growing emphasis on disease mapping and eradication, the availability of accurate and cost-effective diagnostic measures is of paramount importance to global control and elimination efforts. while real-time pcr-based molecular detection assays have shown great promise, to date, these assays have utilized sub-optimal targets. by perfo ... | 2016 | 27027771 |
| evaluation of an fda approved library against laboratory models of human intestinal nematode infections. | treatment options for infections with soil-transmitted helminths (sth) - ascaris lumbricoides, trichuris trichiura and the two hookworm species, ancylostoma duodenale and necator americanus - are limited despite their considerable global health burden. the aim of the present study was to test the activity of an openly available fda library against laboratory models of human intestinal nematode infections. | 2016 | 27363703 |
| heavy metals and parasitic geohelminths toxicity among geophagous pregnant women: a case study of nakuru municipality, kenya. | geophagia is defined as deliberate consumption of earths' materials, e.g. soil, clay and soft stones. the practice is widespread among pregnant women, and there are conflicting views as to whether it is beneficial to health or not. geophagic materials may be a source of micronutrients though the materials may bind the micronutrients thus reducing or hindering their bioavailability in the body. geophagia is closely associated with geohelminthic infections among pregnant women and heavy metal pois ... | 2016 | 25750054 |
| using a health-rating system to evaluate the usefulness of caenorhabditis elegans as a model for anthelmintic study. | soil-transmitted helminths (sths) are intestinal parasitic nematodes that infect humans, and are transmitted through contaminated soil. these nematodes include the large roundworm (ascaris lumbricoides), whipworm (trichuris trichiura), and hookworm (ancylostoma ceylanicum, ancylostoma duodenale, and necator americanus). nearly 1.5 billion people (~24% of the population) worldwide are infected with at least one species of these parasites, burdening the poor, in particular, children and pregnant w ... | 2017 | 28632749 |
| efficiency of two sewage treatment systems (activated sludge and natural lagoons) for helminth egg removal in morocco. | morocco is a country known for its vulnerability of water resources because of its arid and semi-arid climate. thus, recycled wastewater has been suggested for agricultural activities, but contamination of these wastewaters is a major concern. the current study aims to determine the occurrence of helminth eggs in urban wastewater and to evaluate the removal of these pathogens by two sewage treatment systems: activated sludge and natural lagoons. the samples of wastewater and sludge were collecte ... | 2017 | 28797540 |
| efficacy of single-dose 500 mg mebendazole in soil-transmitted helminth infections: a review. | soil-transmitted helminthiasis (sth) is caused by ascaris lumbricoides (roundworm), trichuris trichiura (whipworm), and ancylostoma duodenale and necator americanus (hookworms). mebendazole is one of the recommended preventive chemotherapy agents for sth. this review summarizes the efficacy data from 29 studies with single-dose 500 mg mebendazole in sth treatment and compares the results with those of a recently conducted phase 3 study of a 500 mg mebendazole chewable tablet against a. lumbricoi ... | 2017 | 28716158 |
| an integrated study of human and animal infectious disease in the lake victoria crescent small-holder crop-livestock production system, kenya. | the neglected zoonotic diseases (nzd) are an understudied group that are a major cause of illness throughout the developing world. in general, little is known about the prevalence and burden of nzds in affected communities, particularly in relation to other infectious diseases with which they are often co-endemic. we describe the design and descriptive epidemiological outputs from an integrated study of human and animal zoonotic and non-zoonotic disease in a rural farming community in western ke ... | 2017 | 28666412 |
| hookworm infections among migrant workers in malaysia: molecular identification of necator americanus and ancylostoma duodenale. | ongoing urbanisation of the working population as well as cross-border migration of workers particularly into large cities has contributed to the development and growth of urban slums. these deprived areas are conducive for the transmission of intestinal pathogens including hookworm. the aim of this study was to determine both the prevalence and species identity of hookworm infections among the migrant worker community in malaysia. a total of 388 faecal samples were collected from migrant worker ... | 2017 | 28610937 |
| hookworm infection is associated with decreased cd4+ t cell counts in hiv-infected adult ugandans. | most studies evaluating epidemiologic relationships between helminths and hiv have been conducted in the pre-art era, and evidence of the impact of helminth infections on hiv disease progression remains conflicting. less is known about helminth infection and clinical outcomes in hiv-infected adults receiving antiretroviral therapy (art). we sampled hiv-infected adults for eight gastrointestinal parasites and correlated parasitic infection with demographic predictors, and clinical and immunologic ... | 2017 | 28542260 |
| [gastrointestinal bleeding in newborn with hookworm, national hospital san bartolome. case report]. | we present the case of gastrointestinal bleeding uncinariasis in a newborn baby of 27 days old from anindigenous town of tangoshiri, located in the province of la convencion, department of cuzco, who enters to the service of neonatology national teaching hospital san bartolome in lima, peru, with decompensated severe anemia. the baby has melena since the fourth day of his birth, which increased in the third week of life, with hematocrit of 12%. she was hospitalized, receiving blood transfusion a ... | 2017 | 28489842 |
| [geohelminths]. | millions of people in in rural areas and deprived tropical and subtropical regions are infected by soil-transmitted helminths: ascaris lumbricoides, trichuris trichiura, hookworms (ancylostoma duodenale and necator americanus), and strongyloides stercoralis. large migratory flows have made their worldwide distribution easier. besides being debilitating and producing a significant mortality, they cause high morbidity, leading to physical and intellectual impairment in millions of children who liv ... | 2017 | 26980233 |
| blastocystis subtyping and its association with intestinal parasites in children from different geographical regions of colombia. | blastocystis is a common enteric protist colonizing probably more than 1 billion people with a large variety of non-human hosts. remarkable genetic diversity has been observed, leading to the subdivision of the genus into multiple subtypes (st), some of which are exclusively found in non-human hosts. the aim of this study was to determine the distribution of blastocystis sts/18s alleles in symptomatic (abdominal pain, anal pruritus, diarrhea, headache, nauseas and/or vomit) and asymptomatic chil ... | 2017 | 28222192 |
| detection and quantification of soil-transmitted helminths in environmental samples: a review of current state-of-the-art and future perspectives. | it is estimated that over a billion people are infected with soil-transmitted helminths (sths) globally with majority occurring in tropical and subtropical regions of the world. the roundworm (ascaris lumbricoides), whipworm (trichuris trichiura), and hookworms (ancylostoma duodenale and necator americanus) are the main species infecting people. these infections are mostly gained through exposure to faecally contaminated water, soil or contaminated food and with an increase in the risk of infect ... | 2017 | 28214519 |
| association of community sanitation usage with soil-transmitted helminth infections among school-aged children in amhara region, ethiopia. | globally, in 2010, approximately 1.5 billion people were infected with at least one species of soil-transmitted helminth (sth), ascaris lumbricoides, trichuris trichiura, hookworm (ancylostoma duodenale and necator americanus). infection occurs through ingestion or contact (hookworm) with eggs or larvae in the environment from fecal contamination. to control these infections, the world health organization recommends periodic mass treatment of at-risk populations with deworming drugs. prevention ... | 2017 | 28212668 |
| the molecular speciation of soil-transmitted helminth eggs collected from school children across six endemic countries. | the diagnosis of soil-transmitted helminths (sths; ascaris, trichuris and hookworms) is traditionally based on the demonstration of eggs in stool using microscopic techniques. while molecular techniques are more appropriate to speciate sth species they are seldom applied. in this study we speciated sth eggs from stool using molecular techniques to gain insights into the distribution of both human and animal sth species in the human host. | 2017 | 28100811 |
| diagnosis of intestinal parasites in a rural community of venezuela: advantages and disadvantages of using microscopy or rt-pcr. | a cross-sectional study was carried out to determine the prevalence and diagnostic performance of microscopy and real time pcr (rt-pcr) for 14 intestinal parasites in a venezuelan rural community with a long history of persistent intestinal parasitic infections despite the implementation of regular anthelminthic treatments. a total of 228 participants were included in this study. a multiplex rt-pcr was used for the detection of dientamoeba fragilis, giardia intestinalis, cryptosporidium sp. and ... | 2017 | 28007484 |
| molecular modeling and structural analysis of arylesterase of ancylostoma duodenale. | parasitic worm infection of humans is one of the most commonly prevalent helminth infection that has imposed great impact on society and public health in the developing world. the two species of hookworm, namely ancylostoma duodenale and necator americanus may be primarily responsible for causing parasitic infections in human beings. the highly prevalent areas for ancylostoma duodenale infections are mainly india, middle east, australia, northern africa and other parts of the world. the serum ar ... | 2017 | 27642240 |
| intestinal parasites of children and adults in a remote aboriginal community of the northern territory, australia, 1994-1996. | parasitic infections can adversely impact health, nutritional status and educational attainment. this study investigated hookworm and other intestinal parasites in an aboriginal community in australia from 1994 to 1996. | 2017 | 25960921 |