| phenotypic surface properties (aggregation, adhesion and biofilm formation) and presence of related genes in beneficial vaginal lactobacilli. | to evaluate the phenotypic expression of auto-aggregation, adhesion to mucin and biofilm formation of lactobacilli isolated from human vagina and the presence of related genes. | 2014 | 25195810 |
| the development of probiotic treatment in obesity: a review. | recent studies suggested that manipulation of the composition of the microbial ecosystem in the gut might be a novel approach in the treatment of obesity. such treatment might consist of altering the composition of the microbial communities of an obese individual by administration of beneficial microorganisms, commonly known as probiotics. here, we intend to contribute to the developmental process of probiotic treatment of human obesity. the aim is to review the evidence regarding the potential ... | 2014 | 23886977 |
| effectiveness of lactobacillus helveticus and lactobacillus rhamnosus for the management of antibiotic-associated diarrhoea in healthy adults: a randomised, double-blind, placebo-controlled trial. | broad-spectrum antibiotic use can disrupt the gastrointestinal microbiota resulting in diarrhoea. probiotics may be beneficial in managing this type of diarrhoea. the aim of this 10-week randomised, double-blind, placebo-controlled, parallel study was to investigate the effect of lactobacillus helveticus r0052 and lactobacillus rhamnosus r0011 supplementation on antibiotic-associated diarrhoea in healthy adults. subjects were randomised to receive 1 week of amoxicillin-clavulanic acid (875 mg/12 ... | 2016 | 27169634 |
| calcium phosphate supplementation increases faecal lactobacillus spp. in a randomised trial of young adults. | the aim of the studies was to determine the effects of calcium carbonate and calcium phosphate supplementation on faecal lactobacillus spp., with and without a probiotic supplement, in healthy adults. study 1 comprised of a randomised, double-blind, crossover design; participants (n=15) received 2 capsules/d of 250 mg elemental calcium as calcium carbonate (ca1) and calcium phosphate (ca2) each for 2-week periods, with 2-week baseline and washout periods. study 2 was a randomised, double-blind, ... | 2016 | 26503737 |
| emergency department treatment of children with diarrhea who attend day care: a randomized multidose trial of a lactobacillus helveticus and lactobacillus rhamnosus combination probiotic. | benefits associated with probiotic administration to children seeking emergency department care with diarrheal disease are unknown. | 2015 | 25669920 |
| microbial origin of non proteolytic aminoacyl derivatives in long ripened cheeses. | cheese ripening involves a complex series of biochemical events that contribute to the development of each cheese characteristic taste, aroma and texture. proteolysis, which has been the subject of active research in the last decade, is the most complex of these biochemical events. however, also aminoacyl derivates of non-proteolytic origin (γ-glutamyl-amino acids and lactoyl-amino acids) with interesting sensory properties have been identified in cheeses. in the present work, an enzymatic activ ... | 2013 | 23664262 |
| immune signalling responses in intestinal epithelial cells exposed to pathogenic escherichia coli and lactic acid-producing probiotics. | enterohaemorrhagic escherichia coli o157:h7 and adherent-invasive escherichia coli are two groups of enteric bacterial pathogens associated with haemorrhagic colitis and crohn's disease, respectively. bacterial contact with host epithelial cells stimulates an immediate innate immune response designed to combat infection. in this study, immune responses of human epithelial cells to pathogens, either alone or in combination with probiotic bacteria were studied. industrially prepared lactobacillus ... | 2013 | 23443951 |
| live and heat-killed lactobacillus spp. interfere with streptococcus mutans and streptococcus oralis during biofilm development on titanium surface. | this research investigates the ability of live and heat-killed (hk) lactic acid bacteria (lab) to interfere with streptococcus mutans atcc 25175 and streptococcus oralis atcc 9811 during biofilm formation. | 2017 | 28193570 |
| development of a simple, low-cost and eurytopic medium based on pleurotus eryngii for lactic acid bacteria. | lactic acid bacteria (lab) are a group of important beneficial microorganisms for human, but their growth is restricted to the habitats with rich nutrients. in order to develop a simple, low-cost and efficient medium based on the mushroom pleurotus eryngii, this study evaluated the effects of different treatment methods for the mushroom, concentration of the mushroom, buffers, tween 80, mgso4·7h2o, mnso4·4h2o, cuso4·5h2o, riboflavin and ascorbic acid on the growth of lactococcus lactis subsp. la ... | 2016 | 27590888 |
| effect of inhibition on tyrosinase and melanogenesis of agastache rugosa kuntze by lactic acid bacteria fermentation. | this work presents the first report that a. rugosa could have tyrosinase and melanogenesis inhibition and that its activities also be improved by fermentation with lactobacillus rhamnosus and lactobacillus paracasei. it was found that the tyrosinase and melanogenesis inhibition was correlated with antioxidant activity of acacetin, the major biologically active substances in a. rugosa. | 2016 | 27531590 |
| impact of probiotic synbio(®) administered by vaginal suppositories in promoting vaginal health of apparently healthy women. | the purpose of this study was to investigate whether vaginal administration of probiotic lactobacillus results in their colonization and persistence in the vagina and whether it promotes normalization and maintenance of ph and nugent score. a single-arm, open-label controlled towards the baseline (pre-post) study including 35 apparently healthy women was conducted. each woman was examined three times during the study. women were instructed to receive daily for 7 days, the probiotic suppositories ... | 2016 | 27324341 |
| early probiotics to prevent childhood metabolic syndrome: a systematic review. | to conduct a systematic review of studies on early probiotic supplementation to prevent childhood metabolic syndrome (ms). | 2015 | 26413489 |
| in vitro evaluation on hela cells of protective mechanisms of probiotic lactobacilli against candida clinical isolates. | to characterize in vitro the ability of human lactobacillus strains to inhibit the adhesion, to displace and to compete with clinically isolated candida strains. | 2015 | 26335148 |
| a combination of probiotics and whey proteins enhances anti-obesity effects of calcium and dairy products during nutritional energy restriction in ap2-agouti transgenic mice. | lactobacillus rhamnosus gg, lactobacillus paracasei tmc0409, streptococcus thermophilus tmc1543 and whey proteins were used to prepare fermented milk. for the experiment ap2- agouti transgenic mice were pre-treated with a high-sucrose/high-fat diet for 6 weeks to induce obesity. the obese mice were fed a diet containing 1·2% ca and either non-fat dried milk (nfdm) or probiotic-fermented milk (pfm) with nutritional energy restriction for 6 weeks. the animals were examined after the treatment for ... | 2015 | 25871498 |
| probiotic potential of selected lactic acid bacteria strains isolated from brazilian kefir grains. | a total of 34 lactic acid bacteria isolates from 4 different brazilian kefir grains were identified and characterized among a group of 150 isolates, using the ability to tolerate acidic ph and resistance to bile salts as restrictive criteria for probiotic potential. all isolates were identified by amplified ribosomal dna restriction analysis and 16s rdna sequencing of representative amplicons. eighteen isolates belonged to the species leuconostoc mesenteroides, 11 to lactococcus lactis (of which ... | 2015 | 25841972 |
| decrease in lactobacilli in the intestinal microbiota of celiac children with a gluten-free diet, and selection of potentially probiotic strains. | the intestinal microbiota would be implicated in pathology associated with celiac disease caused by an abnormal immune system reaction against gluten present in cereal grains. the objectives of this work were to detect through basic methods the changes in the composition of the most common genera of bacteria from the intestinal microbiota of symptom-free celiac disease children with a gluten-free diet compared with healthy children from tucumán and to select lactobacilli (lb) strains with probio ... | 2015 | 25438612 |
| prebiotic and synbiotic effects on rats fed malted barley with selected bacteria strains. | butyric acid, one of the key products formed when β-glucans are degraded by the microbiota in the colon, has been proposed to be important for colonic health. glutamine bound to the fibre may have similar effects once it has been liberated from the fibre in the colon. both β-glucans and glutamine are found in high amounts in malted barley. lactobacillus rhamnosus together with malt has been shown to increase the formation of butyric acid further in rats. | 2014 | 25317120 |
| identification and partial characterization of lactic acid bacteria isolated from traditional dairy products produced by herders in the western tianshan mountains of china. | thirty strains of lactic acid bacteria (lab) were isolated from herders' traditional dairy products collected from xinjiang, china. the species lactobacillus, lactococcus, enterococcus, pediococcus and leuconostoc were identified by 16s ribosomal rna gene sequencing analysis and conventional observation. the strains' fermentation characteristics, including milk acidification, proteolysis, autolysis, antimicrobial activity and diacetyl production, were assayed and compared. strains nl24 and nl31 ... | 2014 | 25082064 |
| in vitro evaluation of antimicrobial activity of lactobacillus rhamnosus imc 501(®) , lactobacillus paracasei imc 502(®) and synbio(®) against pathogens. | probiotic lactobacilli have a great potential to produce antimicrobial compounds that inhibit and control the microbial pathogen growth. the antimicrobial and antifungal activities of two probiotic strains, lactobacillus rhamnosus imc 501(®) and lactobacillus paracasei imc 502(®) , and their 1 : 1 combination, named synbio(®) , were studied using four different methods. | 2014 | 24836638 |
| whole genome sequence of the probiotic strain lactobacillus paracasei n1115, isolated from traditional chinese fermented milk. | lactobacillus paracasei n1115 is a new strain with probiotic properties isolated from traditional homemade dairy products in inner mongolia, china. here, we report the complete genome sequence of l. paracasei n1115, which shows high similarity to the well-studied probiotic lactobacillus rhamnosus gg, and 3 structures turned out to be inversions, according to the colinearity analysis of the blast alignment. | 2014 | 24625864 |
| evaluation of antipathogenic activity and adherence properties of human lactobacillus strains for vaginal formulations. | to test different lactobacillus strains for their antipathogenic activity towards candida strains and their adhesion properties for the preparation of vaginal ovules and douches to be used in vaginal candidiasis prevention. | 2014 | 24552173 |
| effect of buckwheat flour and oat bran on growth and cell viability of the probiotic strains lactobacillus rhamnosus imc 501®, lactobacillus paracasei imc 502® and their combination synbio®, in synbiotic fermented milk. | fermented foods have a great significance since they provide and preserve large quantities of nutritious foods in a wide diversity of flavors, aromas and texture, which enrich the human diet. originally fermented milks were developed as a means of preserving nutrients and are the most representatives of the category. the first aim of this study was to screen the effect of buckwheat flour and oat bran as prebiotics on the production of probiotic fiber-enriched fermented milks, by investigating th ... | 2013 | 24140807 |
| induced apoptosis of th2 lymphocytes and inhibition of airway hyperresponsiveness and inflammation by combined lactic acid bacteria treatment. | several lactic acid bacteria (lab) demonstrably regulate the immune system and inhibit allergic disease. this study examined whether oral feeding of either lactobacillus paracasei (l. paracasei) bb5 and/or lactobacillus rhamnosus (l. rhamnosus) bb1 suppresses ovalbumin (ova)-induced airway hyperresponsiveness (ahr) and inflammation in a murine model. ova-specific immune responses, cell profile of bronchoalveolar lavage fluid (balf), and airway ahr were assessed following ova and methacholine cha ... | 2013 | 23142092 |
| antiproliferative and proapoptotic effects of viable or heat-killed lactobacillus paracasei impc2.1 and lactobacillus rhamnosus gg in hgc-27 gastric and dld-1 colon cell lines. | data from literature suggest the possible use of probiotics as chemopreventive agents against colon cancer, but few investigations are available on their effects on gastric cancer proliferation. in our previous study, a specific lactobacillus, strain l. paracasei impc2.1, was demonstrated to colonize the human gut and positively affect fecal bacteria and biochemical parameters. the aims of the present study were to investigate the effects of l. paracasei impc2.1, comparing them with those of lac ... | 2012 | 23061912 |
| functional foods as carriers for synbio®, a probiotic bacteria combination. | the popularity of functional foods continues to increase as consumers desire flavorful foods that will fulfil their health needs. among these foods, probiotics may exert positive effects on the composition of gut microbiota and overall health. however, in order to be beneficial, the bacterial cultures have to remain live and active at the time of consumption. the aim of this study was to develop new probiotic food products, such as seasoned cheeses, salami, chocolate and ice-cream with a final p ... | 2012 | 22727086 |
| pilot-scale production and viability analysis of freeze-dried probiotic bacteria using different protective agents. | the functional food industry requires an improvement of probiotic strain stability during storage, especially when they are stored at room temperature. in this study, the viability of freeze-dried lactobacillus rhamnosus imc 501(®) and lactobacillus paracasei imc 502(®) using different protective agents (i.e., glycerine, mannitol, sorbitol, inulin, dextrin, crystalean(®)) was determined and compared with semi skimmed milk (ssm) control. no significant differences were observed between the tested ... | 2010 | 22254025 |
| investigating the effect of different treatments with lactic acid bacteria on the fate of listeria monocytogenes and staphylococcus aureus infection in galleria mellonella larvae. | the use of galleria mellonella as a model host to elucidate microbial pathogenesis and search for novel drugs and therapies has been well appreciated over the past years. however, the effect of microorganisms with functional appeal in the specific host remains scarce. the present study investigates the effect of treatment with selected lactic acid bacteria (lab) with probiotic potential, as potential protective agents by using live or heat-killed cells at 6 and 24 h prior to infection with liste ... | 2016 | 27618619 |
| meta-analysis of effects of inoculation with homofermentative and facultative heterofermentative lactic acid bacteria on silage fermentation, aerobic stability, and the performance of dairy cows. | forages are usually inoculated with homofermentative and facultative heterofermentative lactic acid bacteria (lab) to enhance lactic acid fermentation of forages, but effects of such inoculants on silage quality and the performance of dairy cows are unclear. therefore, we conducted a meta-analysis to examine the effects of lab inoculation on silage quality and preservation and the performance of dairy cows. a second objective was to examine the factors affecting the response to silage inoculatio ... | 2017 | 28342607 |
| transcriptomic analysis of the innate antiviral immune response in porcine intestinal epithelial cells: influence of immunobiotic lactobacilli. | lactobacillus rhamnosus crl1505 and lactobacillus plantarum crl1506 are immunobiotic strains able to increase protection against viral intestinal infections as demonstrated in animal models and humans. to gain insight into the host-immunobiotic interaction, the transcriptomic response of porcine intestinal epithelial (pie) cells to the challenge with viral molecular associated pattern poly(i:c) and the changes in the transcriptomic profile induced by the immunobiotics strains crl1505 and crl1506 ... | 2017 | 28210256 |
| effects of bacterial direct-fed microbials on ruminal characteristics, methane emission, and milk fatty acid composition in cows fed high- or low-starch diets. | this study investigated the effects of bacterial direct-fed microbials (dfm) on ruminal fermentation and microbial characteristics, methane (ch4) emission, diet digestibility, and milk fatty acid (fa) composition in dairy cows fed diets formulated to induce different ruminal volatile fatty acid (vfa) profiles. eight ruminally cannulated dairy cows were divided into 2 groups based on parity, days in milk, milk production, and body weight. cows in each group were fed either a high-starch (38%, hs) ... | 2017 | 28161181 |
| lactobacillus plantarum hac01 regulates gut microbiota and adipose tissue accumulation in a diet-induced obesity murine model. | the functional features of lactobacillus plantarum hac01 (hac01), isolated from fermented korean kimchi, were studied with regard to the fat mass, immunometabolic biomarkers and dysbiosis in a diet-induced obesity (dio) murine model. l. rhamnosus gg (lgg) served as reference strain and a pbs-treated group as control. the administration of l. plantarum hac01 resulted in reduction of the mesenteric adipose depot, the conjunctive tissue closely associated with the gastrointestinal tract, where lipi ... | 2017 | 27858139 |
| immunobiotic lactobacillus strains reduce small intestinal injury induced by intraepithelial lymphocytes after toll-like receptor 3 activation. | intestinal intraepithelial lymphocytes (iels) play critical roles in disrupting epithelial homeostasis after toll-like receptor (tlr)-3 activation with genomic rotavirus dsrna or the synthetic dsrna analog poly(i:c). the capacity of immunobiotic lactobacillus rhamnosus crl1505 (lr1505) or lactobacillus plantarum crl1506 (lp1506) to beneficially modulate iels response after tlr3 activation was investigated in vivo using a mice model. | 2016 | 27279272 |
| active lactobacillus rhamnosus la68 or lactobacillus plantarum wcfs1 administration positively influences liver fatty acid composition in mice on a hfd regime. | western life style, and high calorie diet in particular is causing major health problems such as insulin resistance, hepatic steatosis and heart disease in the modern age. high fat diet (hfd) induces similar changes in mice, such as increased body weight, hypercholesterolemia and accumulation of triglycerides in the liver. these changes can be ameliorated by the administration of some lactobacillus species. the focus of this study was to analyze the fatty acid content of liver, heart and brain t ... | 2016 | 27231730 |
| bacteriocin-producing strains of lactobacillus plantarum inhibit adhesion of staphylococcus aureus to extracellular matrix: quantitative insight and implications in antibacterial therapy. | in the present study, the adhesion of bacteriocin-producing probiotic strains of lactobacillus plantarum onto extracellular matrix (ecm) proteins such as collagen and mucin and their potential to prevent pathogen invasion onto the ecm was ascertained. fluorescence-based in vitro assays indicated that l. plantarum strains cra21, cra38 and cra52 displayed considerable adhesion to ecm molecules, which was comparable to the probiotic lactobacillus rhamnosus gg. flow cytometry-based quantitative asse ... | 2015 | 26445850 |
| vitamin d receptor pathway is required for probiotic protection in colitis. | low expression of vitamin d receptor (vdr) and dysfunction of vitamin d/vdr signaling are reported in patients with inflammatory bowel disease (ibd); therefore, restoration of vdr function to control inflammation in ibd is desirable. probiotics have been used in the treatment of ibd. however, the role of probiotics in the modulation of vdr signaling to effectively reduce inflammation is unknown. we identified a novel role of probiotics in activating vdr activity, thus inhibiting inflammation, us ... | 2015 | 26159695 |
| anti-tumour immune effect of oral administration of lactobacillus plantarum to ct26 tumour-bearing mice. | colorectal cancer (crc) is one of the most prevalent forms of cancer that shows a high mortality and increasing incidence. there are numerous successful treatment options for crc, including surgery, chemotherapy, radiotherapy and immunotherapy; however, their side effects and limitations are considerable. probiotics may be an effective strategy for preventing and inhibiting tumour growth through stimulation of host innate and adaptive immunity. we investigated and compared potential anti-tumour ... | 2015 | 25963256 |
| cyclooxygenase as a target in chemoprevention by probiotics during 1,2-dimethylhydrazine induced colon carcinogenesis in rats. | the present study was undertaken to assess the effects of potential probiotics in regulating the activity of cyclooxygenase-2 (cox-2) along with other morphological and histological analysis during 1,2-dimethylhydrazine (dmh) induced colon carcinogenesis in rats. the rats were divided into 6 groups viz., normal control, lactobacillus plantarum (adf10) treated, lactobacillus rhamnosus gg (lgg) treated, dmh treated, adf10 + dmh treated and lgg + dmh treated. probiotics were supplemented to rats at ... | 2015 | 25811420 |
| microbial population, chemical composition and silage fermentation of cassava residues. | in order to effectively use the cassava (manihot esculenta crantz) residues, including cassava leaves, peel and pulp for livestock diets, the chemical and microbiological composition, silage preparation and the effects of lactic acid bacteria (lab) inoculants on silage fermentation of cassava residues were studied. these residues contained 10(4) to 10(5) lab and yeasts, 10(3) to 10(4) coliform bacteria and 10(4) aerobic bacteria in colony forming units (cfu) on a fresh matter (fm) basis. the mol ... | 2015 | 25781881 |
| effects of lactobacillus plantarum a7 with probiotic potential on colon cancer and normal cells proliferation in comparison with a commercial strain. | several beneficial effects have been attributed to the probiotic lactic acid bacteria. it was determined that lactobacilli can exert antiproliferative effects on the various cancer cell lines including colon cancer. effects of lactic acid bacteria on colon cancer may vary from strain to strain and there is a need to find the new probiotic strains with tumor suppressing properties through in vitro studies. | 2014 | 25729553 |
| lactobacillus rhamnosus la68 and lactobacillus plantarum wcfs1 differently influence metabolic and immunological parameters in high fat diet-induced hypercholesterolemia and hepatic steatosis. | in this study, two lactobacillus strains (l. rhamnosus la68 and l. plantarum wcfs1) were evaluated for their effects on high fat diet induced pathology in mice. the aim was to determine whether the administration of lactic acid bacteria had beneficial effects on ameliorating pathology. c57bl/6 mice fed a high fat diet were orally administered with the lactobacillus strains. both the metabolic and immunological parameters were analyzed. the administration of both of the strains had beneficial eff ... | 2015 | 25518825 |
| differential immune-stimulatory effects of ltas from different lactic acid bacteria via mapk signaling pathway in raw 264.7 cells. | lipoteichoic acid (lta) is an immune-stimulatory component found in the cell wall of lactic acid bacteria, which are a major group of gram-positive bacteria known to have beneficial health effects in humans. in this study, we evaluated the stimulatory effects of ltas isolated from different lactobacilli species with mouse macrophage raw 264.7 cells. | 2015 | 25433634 |
| distinct immunomodulation of bone marrow-derived dendritic cell responses to lactobacillus plantarum wcfs1 by two different polysaccharides isolated from lactobacillus rhamnosus lock 0900. | the structures of polysaccharides (ps) isolated from lactobacillus rhamnosus lock 0900 and results from stimulation of mouse bone marrow-derived dendritic cells (bm-dc) and human embryonal kidney (hek293) cells stably transfected with toll-like receptors (tlr) upon exposure to these antigens were studied. l. rhamnosus lock 0900 produces ps that differ greatly in their structure. the polymer l900/2, with a high average molecular mass of 830 kda, is a branched heteropolysaccharide with a unique re ... | 2014 | 25107979 |
| efficacy of probiotic therapy on atopic dermatitis in children: a randomized, double-blind, placebo-controlled trial. | to evaluate a therapeutic efficacy of probiotics mixture (probiotics) in the treatment of children with mild-to-moderate atopic dermatitis (ad). | 2014 | 24843795 |
| use of microparticulated whey protein concentrate, exopolysaccharide-producing streptococcus thermophilus, and adjunct cultures for making low-fat italian caciotta-type cheese. | low-fat caciotta-type cheeses were manufactured with partially skim milk (fat content of ~0.3%) alone (lfc); with the supplementation of 0.5% (wt/vol) microparticulated whey protein concentrate (mwpc) (lfc-mwpc); with mwpc and exopolysaccharides (eps)-producing streptococcus thermophilus st446 (lfc-mwpc-eps); and with mwpc, eps-producing strain st446, and lactobacillus plantarum lp and lactobacillus rhamnosus lra as adjunct cultures (lfc-mwpc-eps-a). the non-eps-producing isogenic variant strept ... | 2014 | 24183686 |
| quantitative appraisal of the probiotic attributes and in vitro adhesion potential of anti-listerial bacteriocin-producing lactic acid bacteria. | estimation of bile tolerance, endurance to gastric and intestinal environment and adhesion potential to intestinal cells are significant selection criteria for probiotic lactic acid bacteria (lab). in this paper, the probiotic potential of native bacteriocin-producing lab isolated previously from indigenous source has been determined through quantitative approaches. among fifteen anti-listerial bacteriocin-producing native lab, ten strains were found to be bile tolerant. the presence of bile sal ... | 2013 | 26782735 |
| utilization of lactic acid bacterial genes in synechocystis sp. pcc 6803 in the production of lactic acid. | metabolic pathway engineering of cyanobacteria for the production of industrially important chemicals from atmospheric co2 has generated interest recently. here, we engineered synechocystis sp. pcc 6803 to produce lactic acid using a lactate dehydrogenase (ldh) gene from various lactic acid-producing bacteria, lactococcus lactis (ldhb and ldhx), lactobacillus plantarum (ldhl and ldh), and lactobacillus rhamnosus (ldhl). the lactic acid was secreted outside the cell using a transporter (lldp) gen ... | 2013 | 23649263 |
| selection of lactic acid bacteria to promote an efficient silage fermentation capable of inhibiting the activity of aspergillus parasiticus and fusarium gramineraum and mycotoxin production. | to select lactic acid bacteria with potential silage inoculant properties. the bio-control activity against mycotoxicogenic fungi and the presence of antibiotics resistance gene were also evaluated. | 2013 | 23437822 |
| ability of lactobacillus rhamnosus gaf01 to remove afm1 in vitro and to counteract afm1 immunotoxicity in vivo. | aflatoxin m1 (afm1) has been detected in many parts of the world both in raw milk and many dairy products, causing great economic losses and human disease. unfortunately, there are few studies dealing with afm1 immunotoxicity/interactions with lactic acid bacteria for potential application as a natural preventive agent. the aim of this study was to isolate (from dairy products) food-grade probiotic bacteria able to degrade/bind afm1 in vitro and evaluate whether the same organism(s) could impart ... | 2013 | 23030351 |
| reduction in cholesterol absorption in caco-2 cells through the down-regulation of niemann-pick c1-like 1 by the putative probiotic strains lactobacillus rhamnosus bfe5264 and lactobacillus plantarum nr74 from fermented foods. | hypercholesterolaemia is a major risk factor related to atherosclerosis, and it may be influenced by our diet. this study addresses the impact of lactobacillus rhamnosus bfe5264 (isolated from maasai fermented milk) and lactobacillus plantarum nr74 (from korean kimchi) on the control of cholesterol absorption through down-regulation of niemann-pick c1-like 1 (npc1l1) expression. caco-2 enterocytes were treated with the live, heat-killed (hk) bacteria, bacterial cell wall extracts and metabolites ... | 2013 | 22816655 |
| the probiotic lactobacillus rhamnosus bfe5264 and lactobacillus plantarum nr74 promote cholesterol efflux and suppress inflammation in thp-1 cells. | the balance between the rate of cholesterol uptake/accumulation and the rate of cholesterol efflux is reflected in the amount of lipid accumulation in macrophages. based upon the fact that liver x receptors (lxrs) play a role in cholesterol efflux, we studied the effects of probiotics on cholesterol efflux and anti-inflammatory action in macrophages. we confirmed changes in lxr expression by treatment of lxr-transfected cho-k1 cells with lactic acid bacteria (lab), and co-cultured thp-1 cells wi ... | 2013 | 22806829 |
| lactobacillus rhamnosus bfe 5264 and lactobacillus plantarum nr74 promote cholesterol excretion through the up-regulation of abcg5/8 in caco-2 cells. | the effect of two putative probiotic strains, lactobacillus rhamnosus bfe5264 and lactobacillus plantarum nr74, on the control of cholesterol efflux in enterocytes was assessed by focusing on the promotion of atp-binding cassette sub-family g members 5 and 8 (abcg5 and abcg8). differentiated caco-2 enterocytes were treated with live bacteria, heat-killed bacteria, a bacterial cell wall fraction, and metabolites and were subjected to cholesterol uptake assay, mrna analysis, and protein analyses. ... | 2011 | 26781680 |
| effects of probiotic drop containing lactobacillus rhamnosus, bifidobacterium infantis, and lactobacillus reuteri on salivary streptococcus mutans and lactobacillus levels. | the aim of the present study was to evaluate the effect of a probiotic drop containing lactobacillus rhamnosus, bifidobacterium infantis, and lactobacillus reuteri on salivary counts of streptococcus mutans (sm) and lactobacillus (lb) in children 3-6 years of age. | 2017 | 27994413 |
| the role of probiotics in prevention of oral diseases. | the dynamic development of knowledge in the field of probiotics was commenced at the beginning of the 20th century. since then, many ways of their possible usage in medicine have been established. in accordance with the who, probiotics are live microorganisms, which if applied in adequate amounts may benefit the host. among probiotics, fungi and bacteria are distinguished, and mechanisms of action of these organisms in the oral cavity and gut are parallel. application in dentistry, in prophylaxi ... | 2016 | 27594560 |
| oral lactobacillus rhamnosus gr-1 and lactobacillus reuteri rc-14 to reduce group b streptococcus colonization in pregnant women: a randomized controlled trial. | this study is to examine the effect of lactobacillus rhamnosus gr-1 and lactobacillus reuteri rc-14 taken orally before bedtime on group b streptococcus (gbs)-positive pregnant women with respect to becoming gbs negative. | 2016 | 27590374 |
| probiotic lactobacilli modulate staphylococcus aureus-induced activation of conventional and unconventional t cells and nk cells. | lactobacilli are probiotic commensal bacteria and potent modulators of immunity. when present in the gut or supplemented as probiotics, they beneficially modulate ex vivo immune responsiveness. further, factors derived from several lactobacilli strains act immune regulatory in vitro. in contrast, staphylococcus aureus (s. aureus) is known to induce excessive t cell activation. in this study, we aimed to investigate s. aureus-induced activation of human mucosal-associated invariant t cells (mait ... | 2016 | 27462316 |
| doses lactobacillus reuteri depend on adhesive ability to modulate the intestinal immune response and metabolism in mice challenged with lipopolysaccharide. | the objective of this study was to evaluate the modulatory effects of lactobacillus reuteri zj617 and zj615, which have high and low adhesive abilities, respectively, and lactobacillus rhamnosus gg (lgg) on immune responses and metabolism in mice stimulated with lipopolysaccharide (lps). six c57bl/6 mice per group were orally inoculated with zj617, zj615 or lgg for one week (1 × 10(8) cfu/mouse) and i.p. injected with lps (10 mg/kg) for 24 h. compared with the lps stimulation group, zj615, zj617 ... | 2016 | 27323686 |
| biofilms of vaginal lactobacillus reuteri crl 1324 and lactobacillus rhamnosus crl 1332: kinetics of formation and matrix characterization. | adhesion and biofilm formation are strain properties that reportedly contribute to the permanence of lactobacilli in the human vagina. the kinetics of biofilm formation and the chemical nature of the biofilm matrix formed by lactobacillus reuteri crl (centro de referencia para lactobacilos culture collection) 1324 and lactobacillus rhamnosus crl 1332, vaginal beneficial strains, were evaluated in this work. crystal violet-stained microplate assay and techniques of epifluorescence, electron and c ... | 2016 | 27146055 |
| [non-antibiotic strategies to prevent the recurrence of uncomplicated urinary tract infections in women]. | the aim of all medical treatment is "primum nihil nocere" ("first, do no harm").restoring the integrity of intestinal microbiota and optimising the immune response in recurrent infections, especially in the urinary tract, are treatment alternatives which are closer to this target than the usual focus on antibiotic prevention of recurrence.in the future, antibiotics will continue to be recommended for the prevention of urinary tract infections on a case-by-case basis. however, the problems of an ... | 2016 | 27138235 |
| probiotics [lgg-bb12 or rc14-gr1] versus placebo as prophylaxis for urinary tract infection in persons with spinal cord injury [prosciuttu]: a study protocol for a randomised controlled trial. | urinary tract infections [utis] are very common in people with spinal cord injury [sci]. utis are increasingly difficult and expensive to treat as the organisms that cause them become more antibiotic resistant. among the sci population, there is a high rate of multi-resistant organism [mro] colonisation. non-antibiotic prevention strategies are needed to prevent uti without increasing resistance. probiotics have been reported to be beneficial in preventing utis in post-menopausal women in severa ... | 2016 | 27084704 |
| probiotic lactobacillus rhamnosus gg therapy and microbiological programming in infantile colic: a randomized, controlled trial. | probiotic lactobacillus reuteri and reduced allergen load may lessen the daily crying of colic infants, but the role of lactobacillus rhamnosus gg (lgg) has remained obscure. | 2015 | 26151493 |
| the trpv1 channel in rodents is a major target for antinociceptive effect of the probiotic lactobacillus reuteri dsm 17938. | certain probiotic bacteria have been shown to reduce distension-dependent gut pain, but the mechanisms involved remain obscure. live luminal lactobacillus reuteri (dsm 17938) and its conditioned medium dose dependently reduced jejunal spinal nerve firing evoked by distension or capsaicin, and 80% of this response was blocked by a specific trpv1 channel antagonist or in trpv1 knockout mice. the specificity of dsm action on trpv1 was further confirmed by its inhibition of capsaicin-induced intrace ... | 2015 | 26084409 |
| lactobacillus reuteri glyceraldehyde-3-phosphate dehydrogenase functions in adhesion to intestinal epithelial cells. | this study was aimed to identify key surface proteins mediating the adhesion of lactobacilli to intestinal epithelial cells. by using caco-2 and ipec-j2 cells labeled with sulfo-nhs-biotin in the western blotting, a protein band of an approximately 37 kda was detected on the surface layer of lactobacillus reuteri strains zj616, zj617, zj621, and zj623 and lactobacillus rhamnosus gg. mass spectrometry analysis using the adhesion-related protein from l. reuteri zj617 showed that it was 100% homolo ... | 2015 | 25867279 |
| efficacy of orally applied probiotic capsules for bacterial vaginosis and other vaginal infections: a double-blind, randomized, placebo-controlled study. | to assess the efficacy of orally administered capsules containing the probiotics lactobacillus rhamnosus gr-1 and lactobacillus reuteri rc-14 (lactogyn, jgl, rijeka, croatia) compared to placebo in otherwise healthy women diagnosed with bacterial vaginosis. | 2013 | 23395559 |
| spatiotemporal maps reveal regional differences in the effects on gut motility for lactobacillus reuteri and rhamnosus strains. | commensal bacteria such as probiotics that are neuroactive acutely affect the amplitudes of intestinal migrating motor complexes (mmcs). what is lacking for an improved understanding of these motility effects are region specific measurements of velocity and frequency. we have combined intraluminal pressure recordings with spatiotemporal diameter maps to analyze more completely effects of different strains of beneficial bacteria on motility. | 2013 | 23316914 |
| lactobacillus reuteri protects epidermal keratinocytes from staphylococcus aureus-induced cell death by competitive exclusion. | recent studies have suggested that the topical application of probiotic bacteria can improve skin health or combat disease. we have utilized a primary human keratinocyte culture model to investigate whether probiotic bacteria can inhibit staphylococcus aureus infection. evaluation of the candidate probiotics lactobacillus reuteri atcc 55730, lactobacillus rhamnosus ac413, and lactobacillus salivarius ucc118 demonstrated that both l. reuteri and l. rhamnosus, but not l. salivarius, reduced s. aur ... | 2012 | 22582077 |
| genome sequences of potential probiotic lactobacillus rhamnosus isolates from human infants. | probiotics provide health benefits to their hosts, including modulation of host immune response, inhibition of colonization by pathogens, modulation of the gut microbiota, and epithelial barrier enhancement. here, we present the draft genome sequences of two newly isolated lactobacillus rhamnosus strains of probiotic potential from healthy human infants. | 2017 | 28385840 |
| low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior. | there is increasing concern about potential long-term effects of antibiotics on children's health. epidemiological studies have revealed that early-life antibiotic exposure can increase the risk of developing immune and metabolic diseases, and rodent studies have shown that administration of high doses of antibiotics has long-term effects on brain neurochemistry and behaviour. here we investigate whether low-dose penicillin in late pregnancy and early postnatal life induces long-term effects in ... | 2017 | 28375200 |
| infective endocarditis due to lactobacillus rhamnosus: risks of probiotic consumption in a patient with structural heart disease. | | 2017 | 28372874 |
| early pregnancy probiotic supplementation with lactobacillus rhamnosus hn001 may reduce the prevalence of gestational diabetes mellitus: a randomised controlled trial. | the study aims to assess whether supplementation with the probiotic lactobacillus rhamnosus hn001 (hn001) can reduce the prevalence of gestational diabetes mellitus (gdm). a double-blind, randomised, placebo-controlled parallel trial was conducted in new zealand (nz) (wellington and auckland). pregnant women with a personal or partner history of atopic disease were randomised at 14-16 weeks' gestation to receive hn001 (6×109 colony-forming units) (n 212) or placebo (n 211) daily. gdm at 24-30 we ... | 2017 | 28367765 |
| release of polyphenols is the major factor influencing the bioconversion of rice straw to lactic acid. | in this study, we found that p-coumaric acid (p-ca), ferulic acid (fa), and condensed tannins were released from rice straw during saccharification. the presence of polyphenols prolonged the lag phase and lowered the productivity of lactic acid. p-ca was identified as a key inhibitor. tannins had a lower inhibitory effect than p-ca; fa had little inhibitory effect. acid, alkaline, and ball milling pretreatments elicited different levels of polyphenol release from rice straw. due to the different ... | 2017 | 28349374 |
| anchorless cell surface proteins function as laminin-binding adhesins in lactobacillus rhamnosus fsmm22. | anchorless cell surface proteins (csps) were extracted with 1 m lithium chloride solution from lactobacillus rhamnosus fsmm22. loss of the anchorless csps resulted in a two-fold decrease in fsmm22 cells bound to a constitutive extracellular matrix glycoprotein, laminin, in vitro. dna-binding protein hu, glyceraldehyde-3-phosphate dehydrogenase, lactate dehydrogenase, and 30s ribosomal protein s19 (rpss) were identified by mass spectrometry in the extract as laminin-binding adhesins. among the fo ... | 2017 | 28333282 |
| lactobacillus rhamnosus endocarditis: an unusual culprit in a patient with barlow's disease. | | 2016 | 28302452 |
| effects of a diet-based weight-reducing program with probiotic supplementation on satiety efficiency, eating behaviour traits, and psychosocial behaviours in obese individuals. | this study evaluated the impact of probiotic supplementation (lactobacillus rhamnosus cgmcc1.3724 (lpr)) on appetite sensations and eating behaviors in the context of a weight-reducing program. obese men (n = 45) and women (n = 60) participated in a double-blind, randomized, placebo-controlled trial that included a 12-week weight loss period (phase 1) based on moderate energy restriction, followed by 12 weeks of weight maintenance (phase 2). during the two phases of the program, each subject con ... | 2017 | 28294985 |
| use of imaging techniques to identify efficient controlled release systems of lactobacillus rhamnosus gg during in vitro digestion. | matrix composition plays a crucial role in the controlled release of viable and functional bacteria in the intestine. imaging tools such as electronic and confocal microscopies were used in this work to investigate the influence of matrix composition on matrix integrity and porosity, bacterial spatial distribution and viability during simulated in vitro digestion. l. rhamnosus gg was encapsulated in matrices having different casein/whey protein ratios. the formulation with a casein/whey ratio of ... | 2017 | 28287654 |
| spray dried formulation of 5-fluorouracil embedded with probiotic biomass: in vitro and in vivo studies. | the present study is utilizing the targeted therapeutic approach and antioxidant potential of selected probiotic biomass in mitigating toxic side effects of chemotherapeutic agents. multicomponent carrier system consisting of 5-fluorouracil (5-fu) and selected probiotic strain with higher free radical scavenging activity was prepared using spray drying technique. prepared spray dried microparticles were characterized for various physical, pharmaceutical, and biopharmaceutical properties includin ... | 2017 | 28275899 |
| lactobacillus rhamnosus gg probiotic enteric regimen does not appreciably alter the gut microbiome or provide protection against gvhd after allogeneic hematopoietic stem cell transplantation. | graft-versus-host disease (gvhd) is a major adverse effect associated with allogeneic stem cell transplant. previous studies in mice indicated that administration of the probiotic lactobacillus rhamnosus gg can reduce the incidence of gvhd after hematopoietic stem cell transplant. here we report results from the first randomized probiotic enteric regimen trial in which allogenic hematopoietic stem cell patients were supplemented with lactobacillus rhamnosus gg. gut microbiome analysis confirmed ... | 2017 | 28256022 |
| the effect of non-standard heat treatment of sheep's milk on physico-chemical properties, sensory characteristics, and the bacterial viability of classical and probiotic yogurt. | classical and probiotic set yogurt were made using non-standard heat treatment of sheep's milk at 60°c/5min. physico-chemical properties, sensory characteristics, and the viability of bacteria that originated from cultures in classical and probiotic yogurt were analysed during 21days of storage at 4°c. for the production of yogurt, a standard yogurt culture and a probiotic strain lactobacillus rhamnosus gg were used. at the end of storage time of the classical and probiotic yogurt the totals of ... | 2017 | 28193434 |
| polysaccharides l900/2 and l900/3 isolated from lactobacillus rhamnosus lock 0900 modulate allergic sensitization to ovalbumin in a mouse model. | here, we compared the abilities of polysaccharides l900/2 and l900/3, which were previously isolated from lactobacillus rhamnosus lock 0900, to modulate the immune response to bystander antigens in a mouse model of ovalbumin (ova) sensitization. in vivo, both polysaccharides reduced the levels of ova-specific ige, ige-dependent basophil degranulation and igg2a antibodies, but had no effect on the levels of ova-specific iga or igg1. interestingly, both polysaccharides triggered recall cellular re ... | 2017 | 28165193 |
| dietary therapy in patients with inflammatory arthritis. | context • the exact etiology of rheumatoid disease is currently unknown. changes in the microbiota of the gastrointestinal (gi) tract, chronic bacterial infection of the upper urinary tract, increased permeability of the gi tract, and food sensitivities have been classified among the factors that may cause or aggravate the disease. dietary deficiencies also may render patients more susceptible to inflammatory conditions and disorders of the immunological system. objective • the study intended to ... | 2017 | 28160762 |
| effect of drying methods on protein and dna conformation changes in lactobacillus rhamnosus gg cells by fourier transform infrared spectroscopy. | microencapsulation protects cells against environmental stress encountered during the production of probiotics, which are used as live microbial food ingredients. freeze-drying and spray-drying are used in the preparation of powdered microencapsulated probiotics. this study examines the ability of fourier transform infrared (ftir) spectroscopy to detect differences in cells exposed to freeze-drying and spray-drying of encapsulated lactobacillus rhamnosus gg cells. the ftir analysis clearly demon ... | 2017 | 28132503 |
| dietary prebiotics and bioactive milk fractions improve nrem sleep, enhance rem sleep rebound and attenuate the stress-induced decrease in diurnal temperature and gut microbial alpha diversity. | severe, repeated or chronic stress produces negative health outcomes including disruptions of the sleep/wake cycle and gut microbial dysbiosis. diets rich in prebiotics and glycoproteins impact the gut microbiota and may increase gut microbial species that reduce the impact of stress. this experiment tested the hypothesis that consumption of dietary prebiotics, lactoferrin (lf) and milk fat globule membrane (mfgm) will reduce the negative physiological impacts of stress. male f344 rats, postnata ... | 2016 | 28119579 |
| synbiotic amazonian palm berry (açai, euterpe oleracea mart.) ice cream improved lactobacillus rhamnosus gg survival to simulated gastrointestinal stress. | the effect of açai pulp ice cream and of its supplementation with inulin (i), whey protein concentrate (wc), and/or whey protein isolate (wi) on the viability and resistance to simulated gastrointestinal stress of the probiotic lactobacillus (lb.) rhamnosus gg strain throughout storage at -18 °c for up to 112 days was evaluated and morphological changes during stress were monitored. lb. rhamnosus gg viability was stable in all formulations for up to 112 days of storage, preserving populations ar ... | 2017 | 28106205 |
| lactobacillus rhamnosus gr-1 attenuates induction of hypertrophy in cardiomyocytes but not through secreted protein msp-1 (p75). | previous animal studies have shown that the administration of probiotic lactobacillus rhamnosus can provide a protective effect against ischemia/reperfusion and necrotic injury to the intestine, liver, and heart, as well as a therapeutic effect to the outcome of ischemic injury to the heart, including cardiac hypertrophy and heart failure. we hypothesized that l. rhamnosus gr-1 major secreted protein 1 (msp-1), also known as p75, plays a major role in this phenomenon. experiments using neonatal ... | 2017 | 28085895 |
| oral treatment with lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress. | stress-related disorders involve systemic alterations, including disruption of the intestinal microbial community. given the putative connections between the microbiota, immunity, neural function, and behaviour, we investigated the potential for microbe-induced gut-to-brain signalling to modulate the impact of stress on host behaviour and immunoregulation. | 2017 | 28073366 |
| the association between loading of restorations and secondary caries lesions is moderated by the restoration material elasticity. | secondary caries limits the longevity of restorations and is thought to be associated with faulty restorations, e.g. dentin-restoration interfacial gaps. recent evidence indicates that loading of restorations might aggravate the effects of gaps on interfacial mineral loss. it is unclear if this effect of loading is dose-dependent or not, and if restoration material properties like elasticity moderate the association between load and mineral loss. we hypothesized that mineral loss of secondary le ... | 2017 | 28065621 |
| extensively hydrolyzed casein formula containing lactobacillus rhamnosus gg reduces the occurrence of other allergic manifestations in children with cow's milk allergy: 3-year randomized controlled trial. | children with cow's milk allergy (cma) have an increased risk of other allergic manifestations (ams). | 2016 | 28043872 |
| lactobacillus rhamnosus ncdc17 ameliorates type-2 diabetes by improving gut function, oxidative stress and inflammation in high-fat-diet fed and streptozotocintreated rats. | restoration of dysbiosed gut microbiota through probiotic may have profound effect on type 2 diabetes. in the present study, rats were fed high fat diet (hfd) for 3 weeks and injected with low dose streptozotocin to induce type 2 diabetes. diabetic rats were then fed lactobacillus rhamnosus ncdc 17 and l. rhamnosus gg with hfd for six weeks. l. rhamnosus ncdc 17 improved oral glucose tolerance test, biochemical parameters (fasting blood glucose, plasma insulin, glycosylated haemoglobin, free fat ... | 2016 | 28008783 |
| extensively hydrolyzed casein formula alone or with l. rhamnosus gg reduces β-lactoglobulin sensitization in mice. | extensively hydrolyzed casein formula (ehcf) has been proposed for the prevention and is commonly used for the treatment of cow's milk allergy (cma). the addition of the probiotic lactobacillus rhamnosus gg (lgg) to ehcf may induce faster acquisition of tolerance to cow's milk. the mechanisms underlying this effect are largely unexplored. we investigated the effects of ehcf alone or in combination with lgg on β-lactoglobulin (blg) sensitization in mice. | 2016 | 27992668 |
| dentifrice containing extract of rosmarinus officinalis linn.: an antimicrobial evaluation. | this study aimed to evaluate the antimicrobial activity of a dentifrice containing an alcoholic extract of rosemary on oral bacteria, compared to a commercially available herbal dentifrice. standard strains of streptococcus mutans (atcc 25175), streptococcus oralis (atcc 9811) and lactobacillus rhamnosus (atcc 7469) were used, as well as different toothpastes based on rosemary (tr), on propolis (th), triclosan (positive control) (tpc) and non-fluoridated dentifrice (negative control) (tnc). bact ... | 2016 | 27982224 |
| long-term safety assessment in children who received hydrolyzed protein formulas with lactobacillus rhamnosus gg: a 5-year follow-up. | extensively hydrolyzed (eh) formula with lactobacillus rhamnosus gg (lgg) was demonstrated to alleviate cow's milk allergy (cma) symptoms and promote faster acquisition of tolerance to cow's milk protein. we previously demonstrated that partially hydrolyzed (ph) and eh formulas with lgg supported normal growth in healthy-term infants through 120 days of age. the objective of the current study was to evaluate growth, development, and specific adverse events through 5 years of age in participants ... | 2017 | 27975116 |
| effects of production methods and protective ingredients on the viability of probiotic lactobacillus rhamnosus r0011 in air-dried alginate beads. | the goal of this study was to use a microencapsulation technology to prepare air-dried concentrated cultures of lactobacillus rhamnosus r0011. the cultures were microencapsulated in alginate beads, which were added to a growth medium to allow cell multiplication inside the matrix; the beads were recovered, dipped in protective solutions, and air-dried. the effects of fermentation technology and of the composition of the protective solutions on subsequent survival during air-drying were examined. ... | 2017 | 27900876 |
| the effects of different carbon sources on the antifungal activity by lactic acid bacteria. | lactobacillus rhamnosus r-2002 strain isolated from armenian pickled cheese sample has a fungicide effect, which was carried out by the first-time designed method. the fungicide effect of lab strain was expressed after 5 days of co-cultivation with mucor plumbeus and 6 days of co-cultivation with penicillium aurantioviolaceum. the growth as well as the antifungal activity of l. rhamnosus r-2002 was shown to directly depend on the nature of the medium's carbon source. the antifungal activity of t ... | 2017 | 27896483 |
| a randomised controlled demonstration trial of multifaceted nutritional intervention and or probiotics: the healthy mums and babies (humba) trial. | maternal obesity is associated with adverse pregnancy outcomes and has lifelong negative implications for offspring health. the institute of medicine recommends limited gestational weight gain (gwg) in obese women for optimal maternal and infant outcomes. however, there is a gap regarding an effective and sustainable intervention strategy to achieve this goal. the aim of the healthy mums and babies (humba) demonstration trial is to assess whether a multifaceted nutritional intervention and/or an ... | 2016 | 27884128 |
| lost in translation? the potential psychobiotic lactobacillus rhamnosus (jb-1) fails to modulate stress or cognitive performance in healthy male subjects. | preclinical studies have identified certain probiotics as psychobiotics - live microorganisms with a potential mental health benefit. lactobacillus rhamnosus (jb-1) has been shown to reduce stress-related behaviour, corticosterone release and alter central expression of gaba receptors in an anxious mouse strain. however, it is unclear if this single putative psychobiotic strain has psychotropic activity in humans. consequently, we aimed to examine if these promising preclinical findings could be ... | 2017 | 27865949 |
| impact of probiotics for reducing infections in veterans (improve): study protocol for a double-blind, randomized controlled trial to reduce carriage of staphylococcus aureus. | staphylococcus aureus (s. aureus) is an organism of great public health importance, causing 20,000 deaths annually. decolonization of patients with s. aureus may prevent infections, yet current options are limited to antimicrobials that promote antibiotic resistance and can cause adverse side effects. probiotics have potential to reduce colonization of pathogenic bacteria, representing a promising alternative for s. aureus decolonization, but thus far lack rigorous evaluation. | 2017 | 27836508 |
| high fat diet induced atherosclerosis is accompanied with low colonic bacterial diversity and altered abundances that correlates with plaque size, plasma a-fabp and cholesterol: a pilot study of high fat diet and its intervention with lactobacillus rhamnosus gg (lgg) or telmisartan in apoe(-/-) mice. | atherosclerosis appears to have multifactorial causes - microbial component like lipopolysaccharides (lps) and other pathogen associated molecular patterns may be plausible factors. the gut microbiota is an ample source of such stimulants, and its dependent metabolites and altered gut metagenome has been an established link to atherosclerosis. in this exploratory pilot study, we aimed to elucidate whether microbial intervention with probiotics l. rhamnosus gg (lgg) or pharmaceuticals telmisartan ... | 2016 | 27821063 |
| a randomized clinical trial on the effectiveness of a symbiotic product to decolonize patients harboring multidrug-resistant gram-negative bacilli. | we aimed to evaluate the effectiveness of a symbiotic product to decolonize the intestinal tract of patients harboring multidrug-resistant (mdr) gram-negative bacilli and to prevent nosocomial infections. | 2016 | 27812649 |
| complete genome sequence of lactobacillus rhamnosus strain lrb. | lactobacillus rhamnosus is a gram-positive facultative heterofermentative lactic acid bacterium. it is often isolated from the gastrointestinal tract, mouth, vagina, and fermented dairy products. we have isolated the l. rhamnosus strain lrb from a healthy baby tooth that had naturally fallen out. here, we report the annotated whole-genome sequence of lrb. | 2016 | 27811096 |
| margin integrity and secondary caries of lined or non-lined composite and glass hybrid restorations after selective excavation in vitro. | for deep carious lesions, selective carious tissue removal (leaving soft dentin close to the pulp) is suggested. afterward, different restoration materials, such as resin composites or glass hybrids (ghs), can be placed. many dentists also apply setting or non-setting calcium hydroxide liners before restoration. we compared margin integrity and susceptibility for secondary caries in differently restored premolars in vitro. | 2017 | 27802124 |
| effect of probiotics on vaginal health in pregnancy. effpro, a randomized controlled trial. | preterm delivery is a leading cause of neonatal morbidity and death. it often results from chorioamnionitis, which is a complication of bacterial vaginosis. probiotics are effective in the treatment of bacterial vaginosis in women who were not pregnant; studies in pregnant woman are missing. | 2016 | 27342046 |