| potential of zimbabwean commercial probiotic products and strains of lactobacillus plantarum as prophylaxis and therapy against diarrhoea caused by escherichia coli in children. | to evaluate the potential of commercial fermented products sold in the country, and strains of lactobacillus plantarum (l. plantarum) as prophylaxis and therapy against diarrhoea in children. | 2017 | 28107866 |
| probiotic microorganisms inhibit epithelial cell internalization of botulinum neurotoxin serotype a. | botulinum neurotoxins (bonts) are some of the most poisonous natural toxins known to man and are threats to public health and safety. previous work from our laboratory showed that both bont serotype a complex and holotoxin can bind and transit through the intestinal epithelia to disseminate in the blood. the timing of bont/a toxin internalization was shown to be comparable in both the caco-2 in vitro cell culture and in the oral mouse intoxication models. probiotic microorganisms have been exten ... | 2016 | 27999281 |
| selection of indigenous lactobacillus paracasei cd4 and lactobacillus gastricus btm 7 as probiotic: assessment of traits combined with principal component analysis. | the population of himalayan region is known to consume variety of fermented and non fermented foods and as a result they have been benefited in terms of overall health, because of the associated beneficial microbes. therefore, the focus of the present study was to identify new strains of lactic acid bacteria (lab) from dairy products such as milk (cow, goat, buffalo) and fermented products (curd and buttermilk) with properties suitable for use as probiotic cultures. | 2017 | 28236643 |
| the soil bacterium methylococcus capsulatus bath interacts with human dendritic cells to modulate immune function. | the prevalence of inflammatory bowel disease (ibd) has increased in western countries during the course of the twentieth century, and is evolving to be a global disease. recently we showed that a bacterial meal of a non-commensal, non-pathogenic methanotrophic soil bacterium, methylococcus capsulatus bath prevents experimentally induced colitis in a murine model of ibd. the mechanism behind the effect has this far not been identified. here, for the first time we show that m. capsulatus, a soil b ... | 2017 | 28293233 |
| [lactobacillus rhamnosus gg conditioned medium prevents e. coli meningitis by inhibiting nuclear factor-κb pathway]. | to investigate whether lactobacillus rhamnosus gg conditioned medium(lgg-cm)has preventive effect against e. coli k1-induced neuropathogenicity in vitro by inhibiting nuclear factor-κb (nf-κb) signaling pathway. | 2017 | 28109094 |
| the lectin-like protein 1 in lactobacillus rhamnosus gr-1 mediates tissue-specific adherence to vaginal epithelium and inhibits urogenital pathogens. | the probiotic lactobacillus rhamnosus gr-1 has been documented to survive implantation onto the vaginal epithelium and interfere with urogenital pathogens. however, the molecular mechanisms involved are largely unknown. here, we report for the first time the construction of dedicated knock-out mutants in l. rhamnosus gr-1 to enable the study of gene functions. in a search for genes responsible for the adherence capacity of l. rhamnosus gr-1, a genomic region encoding a protein with homology to l ... | 2016 | 27869151 |
| a combination of lactic acid bacteria regulates escherichia coli infection and inflammation of the bovine endometrium. | uterine function in cattle is compromised by bacterial contamination and inflammation after calving. the objective of this study was to select a combination of lactic acid bacteria (lab) to decrease endometrium inflammation and escherichia coli infection. primary endometrial epithelial cells were cultured in vitro to select the most favorable lab combination modulating basal tissue inflammation and e. coli infection. supernatants were obtained to determine expression of pro-inflammatory cytokine ... | 2017 | 27837977 |
| probiotics, fibre and herbal medicinal products for functional and inflammatory bowel disorders. | functional bowel disorders (fbd), mainly irritable bowel syndrome (ibs) and functional constipation (fc, also called chronic idiopathic constipation), are very common worldwide. inflammatory bowel disease (ibd), including ulcerative colitis and crohn's disease, although less common, has a strong impact on patients' quality of life, as well as being highly expensive for our healthcare. a definite cure for those disorders is still yet to come. over the years, several therapeutic approaches complem ... | 2016 | 27696378 |
| protective role of postbiotic mediators secreted by lactobacillus rhamnosus gg versus lipopolysaccharide-induced damage in human colonic smooth muscle cells. | some beneficial effects of probiotics may be due to secreted probiotic-derived factors, identified as "postbiotic" mediators. the aim of this study was to evaluate whether supernatants harvested from lactobacillus rhamnosus gg (lgg) cultures (atcc53103 strain) protect colonic human smooth muscle cells (hsmcs) from lipopolysaccharide (lps)-induced myogenic damage. | 2016 | 27741159 |
| lectin-like molecules of lactobacillus rhamnosus gg inhibit pathogenic escherichia coli and salmonella biofilm formation. | increased antibiotic resistance has catalyzed the research on new antibacterial molecules and alternative strategies, such as the application of beneficial bacteria. since lectin molecules have unique sugar-recognizing capacities, and pathogens are often decorated with sugars that affect their survival and infectivity, we explored whether lectins from the probiotic strain lactobacillus rhamnosus gg have antipathogenic properties. | 2016 | 27537843 |
| [effect on muc2 gene knockdown in ht29 cells by crispr/cas9 on probiotics-mediated inhibition of e.coli k1 adhesion and invasion]. | to investigate the effects of lactobacillus rhamnosus gg (lgg) for inhibiting e.coli k1 (e44) adhesion and invasion of an intestinal epithelial cell model with muc2 gene knockdown established using crispr-cas9 system. | 2016 | 27320885 |
| in vitro safety assessments and antimicrobial activities of lactobacillus rhamnosus strains isolated from a fermented mare's milk. | safety and probiotic characteristics such as antimicrobial activities of three lactobacillus rhamnosus strains, fsmm15, fsmm22 and fsmm26, previously isolated as potential probiotics from fermented mare's milk were investigated. the three fsmm strains were susceptible to ampicillin, gentamycin, kanamycin, streptomycin, tetracycline and chloramphenicol, whereas they were resistant to erythromycin (minimal inhibitory concentration (mic) = 4-8 µg/ml) and clindamycin (mic = 4 µg/ml); bioconversion o ... | 2017 | 27476815 |
| escherichia coli nissle 1917 protects gnotobiotic pigs against human rotavirus by modulating pdc and nk-cell responses. | lactobacillus rhamnosus gg (lgg), a gram-positive lactic acid bacterium, is one of the most widely used probiotics; while fewer gram-negative probiotics including escherichia coli nissle 1917 (ecn) are characterized. a mechanistic understanding of their individual and interactive effects on human rotavirus (hrv) and immunity is lacking. in this study, noncolonized, ecn-, lgg-, and ecn + lgg-colonized neonatal gnotobiotic (gn) pigs were challenged with hrv. ecn colonization is associated with a g ... | 2016 | 27457183 |
| carbohydrate-binding specificities of potential probiotic lactobacillus strains in porcine jejunal (ipec-j2) cells and porcine mucin. | bacterial lectins are carbohydrate-binding adhesins that recognize glycoreceptors in the gut mucus and epithelium of hosts. in this study, the contribution of lectin-like activities to adhesion of lactobacillus mucosae lm1 and lactobacillus johnsonii pf01, which were isolated from swine intestine, were compared to those of the commercial probiotic lactobacillus rhamnosus gg. both lm1 and pf01 strains have been reported to have good adhesion ability to crude intestinal mucus of pigs. to confirm t ... | 2016 | 27350617 |
| lactobacillus rhamnosus gr-1 limits escherichia coli-induced inflammatory responses via attenuating myd88-dependent and myd88-independent pathway activation in bovine endometrial epithelial cells. | intrauterine escherichia coli infection after calving reduces fertility and causes major economic losses in the dairy industry. we investigated the protective effect of the probiotic lactobacillus rhamnosus gr-1 on e. coli-induced cell damage and inflammation in primary bovine endometrial epithelial cells (beecs). l. rhamnosus gr-1 reduced ultrastructure alterations and the percentage of beecs apoptosis after e. coli challenge. increased messenger rna (mrna) expression of immune response indicat ... | 2016 | 27236308 |
| sex steroid deficiency-associated bone loss is microbiota dependent and prevented by probiotics. | a eubiotic microbiota influences many physiological processes in the metazoan host, including development and intestinal homeostasis. here, we have shown that the intestinal microbiota modulates inflammatory responses caused by sex steroid deficiency, leading to trabecular bone loss. in murine models, sex steroid deficiency increased gut permeability, expanded th17 cells, and upregulated the osteoclastogenic cytokines tnfα (tnf), rankl, and il-17 in the small intestine and the bm. in germ-free ( ... | 2016 | 27111232 |
| differential effects of escherichia coli nissle and lactobacillus rhamnosus strain gg on human rotavirus binding, infection, and b cell immunity. | rotavirus (rv) causes significant morbidity and mortality in children worldwide. the intestinal microbiota plays an important role in modulating host-pathogen interactions, but little is known about the impact of commonly used probiotics on human rv (hrv) infection. in this study, we compared the immunomodulatory effects of gram-positive (lactobacillus rhamnosus strain gg [lgg]) and gram-negative (escherichia coli nissle [ecn]) probiotic bacteria on virulent human rotavirus (virhrv) infection an ... | 2016 | 26800875 |
| non-antibiotic prophylaxis for urinary tract infections. | increasing antimicrobial resistance has stimulated interest in non-antibiotic prophylaxis of recurrent urinary tract infections (utis). well-known steps in the pathogenesis of utis are urogenital colonization and adherence of uropathogens to uroepithelial cell receptors. to prevent colonization in postmenopausal women, vaginal, but not oral, estrogens have been shown to restore the vagina lactobacilli flora, reduce vaginal colonization with enterobacteriaceae, and reduce the number of utis compa ... | 2016 | 27092529 |
| inhibition of enteropathogens adhesion to human enterocyte-like ht-29 cells by a dairy strain of propionibacterium acidipropionici. | adhesion to the host intestinal mucosa is considered relevant for orally delivered probiotics as it prolongs their persistence in the gut and their health promoting effects. classical propionibacteria are microorganisms of interest due to their role as dairy starters as well as for their functions as probiotics. propionibacterium acidipropionici q4, is a dairy strain isolated from a swiss-type cheese made in argentina that displays probiotic potential. in the present work we assessed the ability ... | 2016 | 26925604 |
| isolation and characterization of lactobacilli from human faeces and indigenous fermented foods for their potential application as probiotics. | this study was conducted to select lactobacillus strains from various sources on the basis of their probiotic attributes, such as acid and bile tolerance, binding to intestinal cells, and antimicrobial activity. twelve isolates were obtained from human and food sources and were evaluated against standard probiotic lactobacillus rhamnosus gg (lgg). isolates were also studied for their antibiotic susceptibility. isolate lactobacillus fermentum gpi-6 showed the best survival profile at 0.3% and 1% ... | 2016 | 26928011 |
| lactobacillus rhamnosus gr-1 ameliorates escherichia coli-induced inflammation and cell damage via attenuation of asc-independent nlrp3 inflammasome activation. | escherichia coli is a major environmental pathogen causing bovine mastitis, which leads to mammary tissue damage and cell death. we explored the effects of the probiotic lactobacillus rhamnosus gr-1 on ameliorating e. coli-induced inflammation and cell damage in primary bovine mammary epithelial cells (bmecs). increased toll-like receptor 4 (tlr4), nod1, and nod2 mrna expression was observed following e. coli challenge, but this increase was attenuated by l. rhamnosus gr-1 pretreatment. immunofl ... | 2015 | 26655757 |
| lactobacillus rhamnosus gg supernatant promotes intestinal barrier function, balances treg and th17 cells and ameliorates hepatic injury in a mouse model of chronic-binge alcohol feeding. | impaired intestinal barrier function plays a critical role in alcohol-induced hepatic injury, and the subsequent excessive absorbed endotoxin and bacterial translocation activate the immune response that aggravates the liver injury. lactobacillus rhamnosus gg supernatant (lgg-s) has been suggested to improve intestinal barrier function and alleviate the liver injury induced by chronic and binge alcohol consumption, but the underlying mechanisms are still not clear. in this study, chronic-binge a ... | 2016 | 26617183 |
| potential of lactic acid bacteria at regulating escherichia coli infection and inflammation of bovine endometrium. | about 40% of dairy cattle develop uterine disease during postpartum period, causing infertility. some studies indicate that uterine infection, predominantly by escherichia coli in the first week postpartum, is associated with metritis, an uterus inflammation in which the cow fails to completely clear bacterial contaminants. the aim of this study was to evaluate the potential of four lactic acid bacteria (lab) (lactobacillus rhamnosus, pediococcus acidilactici, lactobacillus reuteri, and lactobac ... | 2016 | 26549120 |
| lactobacillus plantarum lb95 impairs the virulence potential of gram-positive and gram-negative food-borne pathogens in ht-29 and vero cell cultures. | listeria monocytogenes, salmonella enterica and verocytotoxigenic escherichia coli (vtec) are amongst the most important agents responsible for food outbreaks occurring worldwide. in this work, two lactobacillus spp. strains (labs), lactobacillus plantarum (lb95) and lactobacillus paraplantarum (lb13), previously isolated from spontaneously fermenting olive brines, and two reference probiotic strains, lactobacillus casei shirota and lactobacillus rhamnosus gg, were investigated for their ability ... | 2016 | 26506821 |
| high protective efficacy of rice bran against human rotavirus diarrhea via enhancing probiotic growth, gut barrier function, and innate immunity. | previously, we showed that rice bran (rb) was able to reduce human rotavirus (hrv) diarrhea in gnotobiotic pigs. here, we investigated its effect on the growth of diarrhea-reducing probiotic lactobacillus rhamnosus gg (lgg) and escherichia coli nissle (ecn), and the resulting effects on hrv diarrhea, gut epithelial health, permeability and innate immune responses during virulent hrv challenge. on 3, 5, and 7 days of age pigs were inoculated with 2 × 10(4) colony-forming-units lgg+ecn to initiate ... | 2015 | 26459937 |
| op-3 the protective role of lactobacillus rhamnosus gg-derived factors against lps-induced damage of human colonic smooth muscle cells. | impaired gut barrier function has been reported in some functional gastrointestinal (gi) disorders.evidences suggest that gut microbiota affects gi motility in particular lactobacillus species elicits anti-inflammatory activity and exerts protective effects on damage induced by pathogen gram negative-derived lipopolysaccharide(lps).lps produced an oxidative imbalance in human colonic smooth muscle cells (smc) that persists after lps-washout and contributes to smc morphofunctional alterations. | 2015 | 26439544 |
| in vitro inhibition of 4-nitroquinoline-1-oxide genotoxicity by probiotic lactobacillus rhamnosus imc501. | inhibition of 4-nitroquinoline-1-oxide (4-nqo) genotoxicity by a probiotic strain of lactobacillus rhamnosus (imc501) was assessed by the prokaryotic short-term bioassay soschromotest, using escherichia coli pq37 as the target organism. results showed the ability of strain imc501 to rapidly and markedly counteract, in vitro, the dna damage originated by the considered genotoxin. the inhibition was associated with a spectroscopic hypsochromic shift of the original 4-nqo profile and progressive ab ... | 2015 | 26059518 |
| a tyrosine phosphorylation switch controls the interaction between the transmembrane modulator protein wzd and the tyrosine kinase wze of lactobacillus rhamnosus. | one proposed mechanism for assembly of secreted heteropolysaccharides by many gram positive bacteria relies on the coordinated action of a polymerization complex through reversible phosphorylation events. the role of the tyrosine protein kinase transmembrane modulator is, however, not well understood. | 2015 | 25885688 |
| purification, crystallization and preliminary x-ray diffraction analysis of spad, a backbone-pilin subunit encoded by the fimbrial spafed operon in lactobacillus rhamnosus gg. | spad is the predicted backbone-pilin subunit of the spafed pilus, whose loci are encoded by the fimbrial spafed operon in lactobacillus rhamnosus gg, a gram-positive gut-adapted commensal strain with perceived probiotic benefits. in this study, soluble recombinant spad protein was overproduced in escherichia coli and then purified by ni2+-chelating affinity and gel-filtration chromatography. after limited proteolysis with α-chymotrypsin, good-quality crystals of spad were obtained which diffract ... | 2015 | 25615979 |
| in vitro characterization of the digestive stress response and immunomodulatory properties of microorganisms isolated from smear-ripened cheese. | thirty-six microorganisms (twenty-one bacteria, twelve yeasts and three fungi) were isolated from surface-ripened cheeses and subjected to in vitro digestive stress. the approach mimicked gastric and/or duodenal digestion. lactobacillus rhamnosus gg, escherichia coli nissle 1917 and saccharomyces boulardii were used as reference strains. we studied the microorganisms grown separately in culture medium and then included (or not) in a rennet gel. the microorganisms' immunomodulatory abilities were ... | 2015 | 25589362 |
| a selected lactobacillus rhamnosus strain promotes egfr-independent akt activation in an enterotoxigenic escherichia coli k88-infected ipec-j2 cell model. | enterotoxigenic escherichia coli (etec) are important intestinal pathogens that cause diarrhea in humans and animals. although probiotic bacteria may protect against etec-induced enteric infections, the underlying mechanisms are unknown. in this study, porcine intestinal epithelial j2 cells (ipec-j2) were pre-incubated with and without lactobacillus rhamnosus atcc 7469 and then exposed to f4+ etec. increases in tlr4 and nod2 mrna expression were observed at 3 h after f4+ etec challenge, but thes ... | 2015 | 25915861 |
| gut commensal microvesicles reproduce parent bacterial signals to host immune and enteric nervous systems. | ingestion of a commensal bacteria, lactobacillus rhamnosus jb-1, has potent immunoregulatory effects, and changes nerve-dependent colon migrating motor complexes (mmcs), enteric nerve function, and behavior. how these alterations occur is unknown. jb-1 microvesicles (mvs) are enriched for heat shock protein components such as chaperonin 60 heat-shock protein isolated from escherichia coli (groel) and reproduce regulatory and neuronal effects in vitro and in vivo. ingested labeled mvs were detect ... | 2015 | 25392266 |
| characterization of lactobacillus isolated from dairy samples for probiotic properties. | in the present study twelve lactobacillus isolates (lbs 1-lbs 12) were characterized for probiotic properties. out of the twelve, eight isolates (lbs 1-6, 8 and 11) were bile resistant (survival > 50% at 0.3% bile salt w/v) and five isolates (lbs 1, 2, 5, 6 and 11) were found acid ph value resistant (survival > 50% at ph 3). all twelve isolates inhibited the growth of staphylococcus aureus whereas isolate lbs 2 also inhibited the growth of escherichia coli and salmonella typhimurium. antibiotic ... | 2015 | 25771244 |
| effects of lactobacillus johnsonii and lactobacillus reuteri on gut barrier function and heat shock proteins in intestinal porcine epithelial cells. | heat shock proteins (hsps) are a set of highly conserved proteins that can serve as intestinal gate keepers in gut homeostasis. here, effects of a probiotic, lactobacillus rhamnosus gg (lgg), and two novel porcine isolates, lactobacillus johnsonii strain p47-hy and lactobacillus reuteri strain p43-huv, on cytoprotective hsp expression and gut barrier function, were investigated in a porcine ipec-j2 intestinal epithelial cell line model. the ipec-j2 cells polarized on a permeable filter exhibited ... | 2015 | 25847917 |
| use of lactobacillus casei rhamnosus to prevent cholangitis in biliary atresia after kasai operation. | recurrent cholangitis may aggravate cholestatic liver cirrhosis in biliary atresia (ba) after the kasai operation. this pilot study aimed to investigate whether lactobacillus casei rhamnosus has the prophylactic efficacy for recurrent cholangitis in comparison with the conventional neomycin prophylaxis. | 2015 | 25534776 |
| effectiveness of alternative methods for toothbrush disinfection: an in vitro study. | this study aimed to evaluate the effectiveness of alternative methods for toothbrush disinfection. | 2014 | 24971388 |
| dose-dependent effects of lactobacillus rhamnosus on serum interleukin-17 production and intestinal t-cell responses in pigs challenged with escherichia coli. | the mechanism underlying the dose effect of probiotics on ameliorating diarrhea has not been fully elucidated. here, low (1 × 10(9) cfu/ml) or high (1 × 10(11) cfu/ml) doses of lactobacillus rhamnosus atcc 7469 were administered orally to piglets for 1 week before f4 (k88)-positive enterotoxigenic escherichia coli (f4(+) etec) challenge. administration of a low, but not a high, dose of l. rhamnosus decreased the percentage of cd3(+) cd4(+) cd8(-) t cells in the peripheral blood. notably, transie ... | 2014 | 24389928 |
| improvement in th1/th2 immune homeostasis, antioxidative status and resistance to pathogenic e. coli on consumption of probiotic lactobacillus rhamnosus fermented milk in aging mice. | imbalance in th1/th2 immune pathways and cellular antioxidant systems with progressive aging are among the leading causes of increased risk of morbidity and mortality in elderly. although probiotics have been considered to boost immune system, there is a lack of comprehensive analysis of probiotic effects on aging physiology. the present study aimed at determining anti-immunosenescence potential of milk fermented with probiotic lactobacillus rhamnosus (lr) in 16 months old mice by concurrent ana ... | 2014 | 25037247 |
| lactobacillus rhamnosus and its cell-free culture supernatant differentially modulate inflammatory biomarkers in escherichia coli-challenged human dendritic cells. | the intestinal immune system maintains a delicate balance between immunogenicity against invading pathogens and tolerance to the commensal microbiota and food antigens. different strains of probiotics possess the ability to finely regulate the activation of dendritic cells (dc), polarising the subsequent activity of t-cells. nevertheless, information about their underlying mechanisms of action is scarce. in the present study, we investigated the immunomodulatory effects of a potentially probioti ... | 2014 | 24480321 |
| in vitro evaluation of the mucin-adhesion ability and probiotic potential of lactobacillus mucosae lm1. | in this report, we characterized the probiotic potential of lactobacillus mucosae lm1, focusing on its in vitro mucin-adhesion abilities. | 2014 | 24807045 |
| tailoring the probiotic potential of non-starter lactobacillus strains from ripened parmigiano reggiano cheese by in vitro screening and principal component analysis. | non-starter lactic acid bacteria (nslab) inhabiting fermented food have been recently revised as source of probiotic strains. here, we in vitro assessed the potential probiotic aptitude of a de-replicated set of nslab previously isolated from long ripened parmigiano reggiano cheeses (22 lactobacillus rhamnosus, 18 lactobacillus paracasei, 3 lactobacillus casei, 2 lactobacillus harbinensis, and 2 lactobacillus fermentum). most strains showed moderate to good resistance to biological barriers, inc ... | 2014 | 24290648 |
| identification and characterization of toxin-antitoxin systems in strains of lactobacillus rhamnosus isolated from humans. | the toxin-antitoxin gene systems (tass) are present in the genomes of the overwhelming majority of bacteria and archaea. these systems are involved in various cellular regulatory processes (including stress response), and have not been previously investigated in lactobacilli. we identified 6 putative tass with toxins belonging to the maze and rele superfamilies (pemk1-а1lrh, pemk2-а2lrh, pemk3-relb2lrh, rele1lrh, relb3-rele3lrh, and yefm-yoeblrh) in the genomes of annotated strains of lactobacil ... | 2013 | 23727113 |
| adhesive ability means inhibition activities for lactobacillus against pathogens and s-layer protein plays an important role in adhesion. | eighty-five strains of lactobacillus were isolated from the pig intestine and identified by sequencing analysis based on 16s rrna gene, from which five lactobacillus strains with high adhesive ability were selected. the inhibition ability of the five lactobacillus strains with or without s-layer proteins against adherence of escherichia coli k88 and salmonella enteritidis 50335 to caco-2 was evaluated in vitro with lactobacillus rhamnosus gg strain (lgg) as a positive control. in addition, toler ... | 2013 | 23792230 |
| strain-specific probiotics properties of lactobacillus fermentum, lactobacillus plantarum and lactobacillus brevis isolates from brazilian food products. | a total of 234 lab isolates from brazilian food products were initially screened for their ability to survive at ph 2.0. fifty one of the isolates survived and were selected. they were characterized by phenotypic methods, rep-pcr and identified using 16s rrna gene sequencing as lactobacillus fermentum (34 isolates), lactobacillus plantarum (10) and lactobacillus brevis (7). based on being either highly tolerant to bile, showing an ability for auto-aggregation and/or hydrophobic properties, one l ... | 2013 | 23764216 |
| lactobacillus rhamnosus protects human colonic muscle from pathogen lipopolysaccharide-induced damage. | lactobacillus species might positively affect gastrointestinal motility. these gram-positive bacteria bind toll-like receptor 2 (tlr2) that elicits anti-inflammatory activity and exerts protective effects on damage induced by lipopolysaccharide (lps). whether such effect occurs in gastrointestinal smooth muscle has not been established yet. aim of this study was to characterize the effects of lactobacillus rhamnosus gg (lgg) and of supernatants harvested from lgg cultures on human colonic smooth ... | 2013 | 24118564 |
| the expression of adhesin ef-tu in response to mucin and its role in lactobacillus adhesion and competitive inhibition of enteropathogens to mucin. | to analyse the expression of ef-tu in lactobacillus strains with response to mucin exposure and its role in interfering with adhesion of enteropathogens to mucin. | 2013 | 23663754 |
| lactobacillus plantarum cs24.2 prevents escherichia coli adhesion to ht-29 cells and also down-regulates enteropathogen-induced tumor necrosis factor-α and interleukin-8 expression. | the aim of the present study was to evaluate the potential of lactobacillus plantarum cs24.2 to antagonize escherichia coli adhesion and modulate expression of the responses by ht-29 cells of inflammatory molecules to e. coli adhesion. experiments were performed under different adhesion conditions and findings compared with the responses of lactobacillus rhamnosus gg. tests of competitive adhesion, adhesion inhibition and displacement assays were performed for lactobacilli (l. rhamnosus gg and l ... | 2013 | 23586634 |
| study of probiotic potential of four wild lactobacillus rhamnosus strains. | the four wild lactobacillus rhamnosus strains were examined in vitro for resistance to simulated gastro and intestinal juices, adhesion to ht-29 cells, antagonistic activity against enteric pathogens and immunomodulating activity. the strains l. rhamnosus sb5l, j5l and in1l were able to survive in simulated gastro juice while the strain l. rhamnosus sb31l lost viability exposed to simulated gastro juice for 3 h. the four strains had high viability in simulated small intestinal juice with little ... | 2013 | 23528983 |
| inhibition of fe-induced colon oxidative stress by lactobacilli in mice. | iron (fe) can promote hydrogen peroxide (h(2)o(2)) and hydroxyl radical generation in the colonic surface and promote growth of fe-dependent bacteria. some lactobacillus strains are resistant to oxygen free-radicals, allowing them to survive in a fe-modulated mucosal environment and influence colon microbial ecology and redox state. here, we investigated the capacity of lactobacilli with different antioxidant abilities to modify the bacterial profile and prevent oxidative stress in the colon of ... | 2013 | 22990462 |
| the innovative potential of lactobacillus rhamnosus lr06, lactobacillus pentosus lps01, lactobacillus plantarum lp01, and lactobacillus delbrueckii subsp. delbrueckii ldd01 to restore the "gastric barrier effect" in patients chronically treated with ppi: a pilot study. | gastroesophageal reflux disease is a very widespread condition. in europe, it is estimated that about 175 million people suffer from this disease and have to chronically take drugs to increase gastric ph. the proton pump inhibitors (ppis) such as omeprazole, lansoprazole, and esomeprazole are the most widely used drug typology in this regard. however, the inhibition of normal gastric acid secretion has important side effects, the most important being bacterial overgrowth in the stomach and duode ... | 2012 | 22955351 |
| risks associated with high-dose lactobacillus rhamnosus in an escherichia coli model of piglet diarrhoea: intestinal microbiota and immune imbalances. | probiotic could be a promising alternative to antibiotics for the prevention of enteric infections; however, further information on the dose effects is required. in this study, weanling piglets were orally administered low- or high-dose lactobacillus rhamnosus actt 7469 (10(10) cfu/d or 10(12) cfu/d) for 1 week before f4 (k88)-positive escherichia coli challenge. the compositions of faecal and gastrointestinal microbiota were recorded; gene expression in the intestines was assessed by real-time ... | 2012 | 22848393 |
| lactobacilli vs antibiotics to prevent urinary tract infections: a randomized, double-blind, noninferiority trial in postmenopausal women. | growing antibiotic resistance warrants studying nonantibiotic prophylaxis for recurrent urinary tract infections (utis). use of lactobacilli appears to be promising. | 2012 | 22782199 |
| in vitro study of the effect of a probiotic bacterium lactobacillus rhamnosus against herpes simplex virus type 1. | due to the emergence of drug resistance in herpes simplex virus type 1 (hsv-1), researchers are trying to find other methods for treating herpes simplex virus type 1 infections. probiotic bacteria are effective in macrophage activation and may have antiviral activities. | 2017 | 22552453 |
| probiotic factors partially prevent changes to caspases 3 and 7 activation and transepithelial electrical resistance in a model of 5-fluorouracil-induced epithelial cell damage. | the potential efficacy of a probiotic-based preventative strategy against intestinal mucositis has yet to be investigated in detail. we evaluated supernatants (sn) from escherichia coli nissle 1917 (ecn) and lactobacillus rhamnosus gg (lgg) for their capacity to prevent 5-fluorouracil (5-fu)-induced damage to intestinal epithelial cells. a 5-day study was performed. iec-6 cells were treated daily from days 0 to 3, with 1 ml of pbs (untreated control), de man rogosa sharpe (mrs) broth, tryptone s ... | 2012 | 22526145 |
| functional properties of lactobacillus strains isolated from dairy products. | twenty-four acid- and bile-tolerant lactobacilli isolates from dairy products were identified and further in vitro characterized for the presence of functional traits potentially useful for probiotic applications, which included desirable and undesirable traits, such as biofilm formation, ability to inhibit intestinal pathogens, antibiotic susceptibility, and enzyme activity. the majority of examined strains were susceptible to certain antimicrobial agents (streptomycin, gentamicin, clindamycin, ... | 2012 | 22488103 |
| substances released from probiotic lactobacillus rhamnosus gr-1 potentiate nf-κb activity in escherichia coli-stimulated urinary bladder cells. | lactobacillus rhamnosus gr-1 is a probiotic bacterium used to maintain urogenital health. the putative mechanism for its probiotic effect is by modulating the host immunity. urinary tract infections (uti) are often caused by uropathogenic escherichia coli that frequently evade or suppress immune responses in the bladder and can target pathways, including nuclear factor-kappab (nf-κb). we evaluated the role of l. rhamnosus gr-1 on nf-κb activation in e. coli-stimulated bladder cells. viable l. rh ... | 2012 | 22620976 |
| antimicrobial susceptibility of microflora from ovine cheese. | strains identified in ovine cheese and bryndza by matrix-assisted laser desorption/ionization time-of-flight analysis belonged to ten species of non-enterococcal lactic acid bacteria and included lactobacillus casei/lactobacillus paracasei, lactobacillus plantarum, lactobacillus rhamnosus, lactobacillus helveticus, lactobacillus delbrueckii, lactobacillus fermentum, lactobacillus brevis, lactococcus lactis, pediococcus pentosaceus and pediococcus acidilactici. the susceptibility toward antibioti ... | 2012 | 22491987 |
| probiotics in the management of inflammatory bowel disease: a systematic review of intervention studies in adult patients. | mounting evidence suggests an important role for the intestinal microbiota in the chronic mucosal inflammation that occurs in inflammatory bowel disease (ibd), and novel molecular approaches have further identified a dysbiosis in these patients. several mechanisms of action of probiotic products that may interfere with possible aetiological factors in ibd have been postulated. | 2012 | 22512365 |
| cloning and characterization of a thermostable h2o-forming nadh oxidase from lactobacillus rhamnosus. | nadh oxidase (nox) catalyzes the conversion of nadh to nad(+). a previously uncharacterized nox gene (lrnox) was cloned from lactobacillus rhamnosus and overexpressed in escherichia coli bl21(de3). sequence analysis revealed an open reading frame of 1359 bp, capable of encoding a polypeptide of 453 amino acid residues. the molecular mass of the purified lrnox enzyme was estimated to be ~50 kda by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and 100 kda by gel filtration chromatogra ... | 2012 | 22418266 |
| the major secreted protein msp1/p75 is o-glycosylated in lactobacillus rhamnosus gg. | although the occurrence, biosynthesis and possible functions of glycoproteins are increasingly documented for pathogens, glycoproteins are not yet widely described in probiotic bacteria. nevertheless, knowledge of protein glycosylation holds important potential for better understanding specific glycan-mediated interactions of probiotics and for glycoengineering in food-grade microbes. | 2012 | 22297095 |
| faecal metaproteomic analysis reveals a personalized and stable functional microbiome and limited effects of a probiotic intervention in adults. | recent metagenomic studies have demonstrated that the overall functional potential of the intestinal microbiome is rather conserved between healthy individuals. here we assessed the biological processes undertaken in-vivo by microbes and the host in the intestinal tract by conducting a metaproteome analysis from a total of 48 faecal samples of 16 healthy adults participating in a placebo-controlled probiotic intervention trial. half of the subjects received placebo and the other half consumed la ... | 2016 | 27070903 |
| lactobacillus rhamnosus cncm i-3690 and the commensal bacterium faecalibacterium prausnitzii a2-165 exhibit similar protective effects to induced barrier hyper-permeability in mice. | impaired gut barrier function has been reported in a wide range of diseases and syndromes and in some functional gastrointestinal disorders. in addition, there is increasing evidence that suggests the gut microbiota tightly regulates gut barrier function and recent studies demonstrate that probiotic bacteria can enhance barrier integrity. here, we aimed to investigate the effects of lactobacillus rhamnosus cncm i-3690 on intestinal barrier function. in vitro results using a caco-2 monolayer cell ... | 2015 | 25517879 |
| lactobacillus rhamnosus gg antagonizes giardia intestinalis induced oxidative stress and intestinal disaccharidases: an experimental study. | the present study describes the in vivo modulatory potential of lactobacillus rhamnosus gg (lgg), an effective probiotic, in giardia intestinalis-infected balb/c mice. experimentally, it was observed that oral administration of lactobacilli prior or simultaneous with giardia trophozoites to mice, efficiently (p < 0.05) reduced both the severity and duration of giardiasis. more specifically, probiotics fed, giardia-infected mice, showed a significant increase in the levels of antioxidants [reduce ... | 2013 | 23361971 |
| the use of the probiotic lactobacillus rhamnosus gg and viral findings in the nasopharynx of children attending day care. | limited data are available on the effects of probiotics on the nasopharyngeal presence of respiratory viruses in children attending day care. in this substudy of a randomized, double-blinded, placebo-controlled 28-week intervention study, nasopharyngeal swab samples were collected, on visits to a physician due to symptoms of infection, from children receiving control milk (n = 97) and children receiving the same milk supplemented with probiotic lactobacillus rhamnosus gg (n = 97). the presence o ... | 2013 | 23794458 |
| maternal supplementation with lgg reduces vaccine-specific immune responses in infants at high-risk of developing allergic disease. | probiotics are defined as live micro-organisms that when administered in adequate amounts confer a health benefit on the host. among their pleiotropic effects, inhibition of pathogen colonization at the mucosal surface as well as modulation of immune responses are widely recognized as the principal biological activities of probiotic bacteria. in recent times, the immune effects of probiotics have led to their application as vaccine adjuvants, offering a novel strategy for enhancing the efficacy ... | 2013 | 24324465 |
| effects of early prebiotic and probiotic supplementation on development of gut microbiota and fussing and crying in preterm infants: a randomized, double-blind, placebo-controlled trial. | to evaluate the impact of early prebiotic and probiotic intervention on preterm infants' well-being, crying, growth, and microbiological programming. | 2013 | 23915796 |
| systematic review with meta-analysis: lactobacillus rhamnosus gg in the prevention of antibiotic-associated diarrhoea in children and adults. | the effects of probiotics are strain specific. the clinical effects of each strain need to be evaluated separately. | 2015 | 26365389 |
| probiotic bacterial and fungal strains: claims with evidence. | probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit for the host. this review summarizes current (i.e. published in the last 5 years) key evidence on probiotic efficacy and its safety in adults and children. to identify relevant data, searches of medline and the cochrane library databases were performed in august 2015 to locate randomized controlled trials (rcts) or their meta-analyses. the focus was on commonly used, well-specified, bacterial ... | 2016 | 27028756 |
| the use of probiotics in pediatric gastroenterology: a review of the literature and recommendations by latin-american experts. | the stability and composition of intestinal flora plays a vital role in human wellbeing throughout life from as early as birth. over the past 50 years, several studies have been conducted to evaluate the effect of probiotic administration in pediatric gastroenterology. this document aims to provide a recommendation score on probiotic utilization in pediatric gastroenterology, together with a review of current knowledge concerning its benefits, tolerability, and safety. | 2015 | 25799959 |
| probiotic screening and safety evaluation of lactobacillus strains from plants, artisanal goat cheese, human stools, and breast milk. | the aim of this study was to select autochthonous strains of lactobacillus from stools of healthy infants and adults, human milk, artisanal goat cheese, and fruits and vegetables according to their probiotic properties and safety. from 421 strains of lactobacillus isolated, 102 (24.2%) were shown to be tolerant to gastric ph and bile salts; they were used to determine their anti-helicobacter pylori (agar diffusion assay), antioxidant (oxygen radical absorption capacity), and anti-inflammatory (i ... | 2014 | 24433075 |
| [lactobacillus rhamnosus gg supplementation to reduce side-effects of anti-helicobacter pylori treatment]. | helicobacter pylori (hp) eradication fails in about 10% of patients because of the occurrence of resistance to antibiotics and side-effects. during anti h.pylori therapy, probiotics have been used to reduce the incidence of side-effects. | 2013 | 23838939 |
| probiotics reduce necrotizing enterocolitis severity in hiv-exposed premature infants. | to assess the effect of probiotics on the incidence of necrotizing enterocolitis (nec) in premature infants born to human immunodeficiency virus (hiv)-positive and hiv-negative women. | 2015 | 25724213 |
| mucosal siv vaccines comprising inactivated virus particles and bacterial adjuvants induce cd8(+) t-regulatory cells that suppress siv-positive cd4(+) t-cell activation and prevent siv infection in the macaque model. | a new paradigm of mucosal vaccination against human immunodeficiency virus (hiv) infection has been investigated in the macaque model. a vaccine consisting of inactivated simian immunodeficiency virus (siv)mac239 particles together with a living bacterial adjuvant (either the calmette and guerin bacillus, lactobacillus plantarum or lactobacillus rhamnosus) was administered to macaques via the vaginal or oral/intragastric route. in contrast to all established human and veterinary vaccines, these ... | 2014 | 25071760 |
| peptide extracts from cultures of certain lactobacilli inhibit helicobacter pylori. | helicobacter pylori inhibition by probiotic lactobacilli has been observed in vitro and in vivo. carefully selected probiotic lactobacillus strains could therefore play an important role in the treatment of h. pylori infection and eradication. however, the underlying mechanism for this inhibition is not clear. the aim of this study was to examine if peptide extracts, containing bacteriocins or other antibacterial peptides, from six lactobacillus cultures (lactobacillus acidophilus la1, lactobaci ... | 2010 | 26780898 |
| micronutrient supplemented probiotic yogurt for hiv-infected adults taking haart in london, canada. | the human immunodeficiency virus has devastating effects worldwide. the burden is less pronounced, but still present in canada where approximately 64,000 men and women are hiv positive. the virus and the life-saving antiretroviral therapies often contribute to diarrhea and other gastrointestinal disturbances. certain probiotic organisms, such as lactobacillus rhamnosus gr-1, have been shown to alleviate diarrhea as well as delay the decline of cd4 lymphocytes in some subjects. in addition, micro ... | 2014 | 22825497 |
| the effect of lactobacillus crispatus and lactobacillus rhamnosusculture supernatants on expression of autophagy genes and hpv e6 and e7 oncogenes in the hela cell line. | the aim of this study was to clarify the mechanism by which lactobacilli exert their cytotoxic effects on cervical cancer cells. in addition, we aimed to evalu- ate the effect of lactobacilli on the expression of human papilloma virus (hpv) onco- genes. | 2016 | 26862519 |
| nonpathogenic lactobacillus rhamnosus activates the inflammasome and antiviral responses in human macrophages. | in this study, we have utilized global gene expression profiling to compare the responses of human primary macrophages to two closely related, well-characterized lactobacillus rhamnosus strains gg and lc705, since our understanding of the responses elicited by nonpathogenic bacteria in human innate immune system is limited. macrophages are phagocytic cells of the innate immune system that perform sentinel functions to initiate appropriate responses to surrounding stimuli. macrophages that reside ... | 2017 | 22895087 |
| production of folate in oat bran fermentation by yeasts isolated from barley and diverse foods. | the focus of the research was to identify yeasts from barley kernels in order to study their folate production capability while maintaining high viscosity caused by soluble fibres in oat bran fermentation. | 2014 | 24916316 |
| the preliminary study of prebiotic potential of polish wild mushroom polysaccharides: the stimulation effect on lactobacillus strains growth. | according to the vast body of evidence demonstrating that the intestinal microbiota is undoubtedly linked with overall health, including cancer risk, searching for functional foods and novel prebiotic influencing on beneficial bacteria is necessary. the present study aimed to investigate the potential of polysaccharides from 53 wild-growing mushrooms to stimulate the growth of lactobacillus acidophilus and lactobacillus rhamnosus and to determine the digestibility of polysaccharide fractions. | 2017 | 28353071 |
| survival of probiotics in hypromellose capsules with rice or potato maltodextrin excipient. | there is currently no authorized or established therapeutic level/dose of probiotics for proposed health benefits; however, a daily probiotic consumption of 10(8) to 10(10) cfu has been recommended. this study determined the survival of 5 individual probiotic strains, lactobacillus rhamnosus, lactobacillus paracasei, lactobacillus plantarum, lactobacillus acidophilus, and bifidobacterium lactis, along with a mixture of the 5 strains in hypromellose capsules with rice or potato maltodextrin at 4, ... | 2016 | 27681165 |
| application of lactic acid bacteria in removing heavy metals and aflatoxin b1 from contaminated water. | in this study selected lactic acid bacteria (lab, lactobacillus acidophilus, lactobacillus rhamnosus, lactobacillus plantrium and streptococcus thermophiles) and probiotic bacteria (bifidobacterium angulatum) were tested for their ability in removing heavy metals (hm) including cadmium (cd), lead (pb) and arsenic (as) as well as aflatoxin b1 (afb1) from contaminated water. the biosorption parameters (ph, bacterial concentration, contact time and temperature) of removal using individual as well a ... | 2017 | 27508367 |
| addition of grape pomace extract to probiotic fermented goat milk: the effect on phenolic content, probiotic viability and sensory acceptability. | grape pomace is a source of phenolic compounds, which are associated with health benefits in humans. additionally, fermented dairy foods with probiotics can be good vehicles to deliver these bioactive compounds. the effects of the addition of grape pomace extract (gpe) on the total phenolic (tp) content, physico-chemical characteristics and viability of lactobacillus acidophilus la-5 or lactobacillus rhamnosus hn001 in fermented goat milks prepared with grape juice were investigated. | 2017 | 27282819 |
| [the immunomodulatory and anti-allergy effects of lactobacilli]. | this study was conducted to evaluate the potent immunomodulatory effects of lactobacilli and their possible anti-allergic effects. | 2016 | 27263293 |
| characterization of biosurfactants produced by lactobacillus spp. and their activity against oral streptococci biofilm. | lactic acid bacteria (lab) can interfere with pathogens through different mechanisms; one is the production of biosurfactants, a group of surface-active molecules, which inhibit the growth of potential pathogens. in the present study, biosurfactants produced by lactobacillus reuteri dsm 17938, lactobacillus acidophilus dds-1, lactobacillus rhamnosus atcc 53103, and lactobacillus paracasei b21060 were dialyzed (1 and 6 kda) and characterized in term of reduction of surface tension and emulsifying ... | 2016 | 27102127 |
| antilisterial bacteriocin from lactobacillus rhamnosus cjnu 0519 presenting a narrow antimicrobial spectrum. | a lactic acid bacterium presenting antimicrobial activity against a lactobacillus acidophilus strain used for eradication of acid inhibition was isolated from a natural cheese. the 16s rrna gene sequence of the isolate best matched with a strain of l. rhamnosus and was designated l. rhamnosus cjnu 0519. the antimicrobial activity of the partially purified bacteriocin of cjnu 0519 was abolished when treated with a protease, indicating the protein nature of the bacteriocin. the partially purified ... | 2015 | 26761811 |
| lactic acid bacteria protect human intestinal epithelial cells from staphylococcus aureus and pseudomonas aeruginosa infections. | staphylococcus aureus and pseudomonas aeruginosa are opportunistic pathogens that cause nosocomial and food-borne infections. they promote intestinal diseases. gastrointestinal colonization by s. aureus and p. aeruginosa has rarely been researched. these organisms spread to extra gastrointestinal niches, resulting in increasingly progressive infections. lactic acid bacteria are gram-positive bacteria that produce lactic acid as the major end-product of carbohydrate fermentation. these bacteria i ... | 2015 | 26681052 |
| assessment of the in vitro antimicrobial activity of lactobacillus species for identifying new potential antibiotics. | the bacteriocin-mediated antimicrobial properties of lactobacillus spp. have been widely studied, leading to the use of these micro-organisms in the food industry as preservative agents against foodborne pathogens. in an era in which antibiotic resistance is becoming a public health issue, the antimicrobial activity of lactobacillus spp. could be used for the discovery of new potential antibiotics. thus, it is essential to have an accurate method of screening the production of antimicrobial agen ... | 2015 | 26163158 |
| probiotic bacteria inhibit the bovine respiratory pathogen mannheimia haemolytica serotype 1 in vitro. | this study evaluated the potential of probiotic bacteria to inhibit growth and cell adhesion of the bovine respiratory pathogen mannheimia haemoltyica serotype 1. the inhibitory effects of nine probiotic strains (lactobacillus acidophilus, lactobacillus casei, lactobacillus helveticus, lactobacillus plantarum, lactobacillus rhamnosus, lactococcus lactis, streptococcus thermophilus and two paenibacillus polymyxa strains) against m. haemolytica were evaluated using a spot-on-lawn method. probiotic ... | 2017 | 28178767 |
| cheese supplemented with probiotics reduced the candida levels in denture wearers -rct. | the access to probiotics should be facilitated in order to encourage their usage. we evaluated the effect of consumption of two experimental probiotic-containing cheese on the oral colonization of candida in denture wearers. | 2017 | 28346730 |
| non-saccharomyces yeasts protect against epithelial cell barrier disruption induced by salmonella enterica subsp. enterica serovar typhimurium. | the human gastrointestinal epithelium makes up the largest barrier separating the body from the external environment. whereas invasive pathogens cause epithelial barrier disruption, probiotic micro-organisms modulate tight junction regulation and improve epithelial barrier function. in addition, probiotic strains may be able to reduce epithelial barrier disruption caused by pathogenic species. the aim of this study was to explore non-saccharomyces yeast modulation of epithelial cell barrier func ... | 2015 | 26280244 |
| cholesterol assimilation by lactobacillus probiotic bacteria: an in vitro investigation. | excess cholesterol is associated with cardiovascular diseases (cvd), an important cause of mortality worldwide. current cvd therapeutic measures, lifestyle and dietary interventions, and pharmaceutical agents for regulating cholesterol levels are inadequate. probiotic bacteria have demonstrated potential to lower cholesterol levels by different mechanisms, including bile salt hydrolase activity, production of compounds that inhibit enzymes such as 3-hydroxy-3-methylglutaryl coenzyme a, and chole ... | 2014 | 25295259 |
| effect of the bread-making process on zearalenone levels. | the effects of the bread-making process including fermentation with saccharomyces cerevisiae and lactic acid bacteria (lactobacillus casei, lactobacillus rhamnosus, lactobacillus acidophilus and lactobacillus fermentum) and baking at 200°c on zearalenone (zea) levels were investigated. standard solutions of zea were added to flour and then loaves of bread were prepared. sourdough and three types of yeast including active dry yeast, instant dry yeast and compressed yeast were used for the ferment ... | 2014 | 25291600 |
| eruca sativa might influence the growth, survival under simulated gastrointestinal conditions and some biological features of lactobacillus acidophilus, lactobacillus plantarum and lactobacillus rhamnosus strains. | the growth and viability of three lactobacillus strains, lactobacillus acidophilus, lactobacillus plantarum and lactobacillus rhamnosus, after their passage through simulated gastric and pancreatic juices were studied as a function of their presence in the growth medium of rocket salad (eruca sativa). the presence of e. sativa affected some of the biological properties of the strains. for example, l. acidophilus and l. plantarum worked more efficiently in the presence of e. sativa, increasing no ... | 2014 | 25275269 |
| synbiotic (lactobacillus rhamnosus+lactobacillus acidophilus+inulin) attenuates oxidative stress and colonic damage in 1,2 dimethylhydrazine dihydrochloride-induced colon carcinogenesis in sprague-dawley rats: a long-term study. | the inexorable increase in the incidence of colorectal cancer has led to growing interest in its prevention by natural interventions. thus, the present study was designed with the aim of delineating the antioxidative and antitumorigenic effects of synbiotics in experimental colon carcinogenesis. it was observed that administration of a synbiotic, before 1,2 dimethylhydrazine dihydrochloride (dmh)-induced colon carcinogenesis in sprague-dawley rats, led to increased body weight and growth rate, a ... | 2014 | 25025584 |
| co-culture fermentation of peanut-soy milk for the development of a novel functional beverage. | most of the commercial probiotic products are dairy-based, and the development of non-dairy probiotic products could be an alternative for new functional products. the peanut-soy milk (psm(1)) was inoculated with six different lactic acid bacteria (lab), including probiotic strains and yeasts and fermentation was accomplished for 24h at 37 °c and afterwards, another 24h at ±4 °c. the pediococcus acidilactici (ufla bffcx 27.1), lactococcus lactis (cct 0360), lactobacillus rhamnosus (lr 32) probio ... | 2014 | 24984220 |
| fermentation adaptability of three probiotic lactobacillus strains to oat, germinated oat and malted oat substrates. | functional foods targeting the improvement of gastrointestinal health are widely recognized; of these, dairy-based probiotics are the most popular. thus, the design of nondairy probiotics applying fruits, vegetables and cereals has raised great interest in the healthy food sector. the objective of this work was to assess the potential of germinated and malted oat substrates to support the growth of the probiotic cultures lactobacillus acidophilus, lactobacillus casei and lactobacillus rhamnosus. ... | 2014 | 24979232 |
| the effect of probiotics (lactobacillus rhamnosus hn001, lactobacillus paracasei lpc-37, and lactobacillus acidophilus ncfm) on the availability of minerals from dutch-type cheese. | the use of probiotic cultures in the production of dutch-type cheeses did not lead to significant changes in their chemical composition but it lowered their acidity. the availability of calcium and magnesium analyzed by in vitro enzymatic hydrolysis was 19 and 35%, respectively; the availability of phosphorus was significantly higher, at >90%. the use of probiotic cultures significantly increased the availability of calcium (~2.5%), phosphorus (~6%), and magnesium (~18%). the in vitro method sup ... | 2014 | 24913654 |
| use of probiotics for management of acute gastroenteritis: a position paper by the espghan working group for probiotics and prebiotics. | the use of probiotics has been suggested in the treatment of acute gastroenteritis (age) in addition to early rehydration and avoidance of dietary restrictions. this document provides recommendations for the use of probiotics for the treatment of age in previously healthy infants and children based on a systematic review of previously completed systematic reviews and of randomized controlled trials (rcts) published subsequently to these reviews. the recommendations were formulated only if at lea ... | 2014 | 24614141 |
| shelf life stability of lactobacilli encapsulated in raspberry powder: insights into non-dairy probiotics. | study the shelf-life quality changes in raspberry juice with encapsulated lactobacilli (lactobacillus rhamnosus nrrl b-4495 and lactobacillus acidophilus nrrl b-442) obtained by spray drying and understand the various factors involved. | 2014 | 24438190 |
| effects of probiotics on the recurrence of bacterial vaginosis: a review. | bacterial vaginosis (bv) is a common cause of genital discomfort in women in reproductive ages, which causes many complications. bacterial vaginosis is usually treated by metronidazole and clindamycin. however, this protocol does not prevent its recurrence, which is a main complaint of the patients. the number of lactobacilli in the vagina of women with bv is significantly lower than that in healthy women. hence, efforts have been made to normalize vaginal flora by oral or vaginal administration ... | 2014 | 24299970 |