Publications

TitleAbstractYear
Filter
PMID
Filter
free-radical scavenging properties and antioxidant activities of botryosphaeran and some other β-d-glucans.β-d-glucans are known to present antitumor, anticancer, and anti-inflammatory activities that are influenced by their own antioxidant capacity. the antioxidant activity of botryosphaeran, an exopolysaccharide of the (1 → 3;1 → 6)-β-d-glucan type produced by the botryosphaeria rhodina mamb-05 was evaluated and compared to some other β-d-glucans (lasiodiplodan an exocellular (1 → 6)-β-d-glucan from lasiodiplodia theobromae, laminarin and curdlan), and oligosaccharides, disaccharides, and monosacch ...201525128096
dieback and sooty canker of ficus trees in egypt and its control.this study was designed to throw lights on dieback and canker disease on urban trees of ficus sp. in egypt, its causal pathogens and disease control. diseased samples were collected from five locations. pathogenicity test was done on one year old of three different healthy seedlings of ficus trees (ficus benghalensis, ficu snitida and ficus hawaii). lasiodiplodia theobromae and phomopsis sp. were consistently isolated from infected tissues and were pathogenic. the fungicides antracol combi and t ...201424897790
degradation of pahs in soil by lasiodiplodia theobromae and enhanced benzo[a]pyrene degradation by the addition of tween-80.benzo[a]pyrene (bap), a five-ring polycyclic aromatic hydrocarbon (pah), which has carcinogenic potency, is highly recalcitrant and resistant to microbial degradation. a novel fungus, lasiodiplodia theobromae (l. theobromae), which can degrade bap as a sole carbon source in liquid, was isolated in our laboratory. to prompt the further application of l. theobromae in remediation of sites polluted by bap and other pahs, the present study was targeted toward the removal of bap and pahs from soil by ...201424878554
[study of production of sesquiterpenes of aquilaria senensis stimulated by lasiodiplodia theobromae].to investigate the mechanism of agarwood formation in aquilaria sinensis induced by lasiodiplodia theobromae, the fermentation liquor of l. theobromae was analyzed qualitatively and quantitatively by gas chromatography-mass spectrometry (gc-ms). jas were detected in the fermentation liquor. the effect of the fermentation liquor on the abundance of sesquiterpenes in the callus of a. sinensis was analyzed by solid phase microextraction-gas chromatography-mass spectrometry (spme-gc-ms). and the fer ...201424761630
effect of culture media and environmental factors on mycelial growth and pycnidial production of lasiodiplodia theobromae in physic nut (jatropha curcas).physic nut (jatropha curcas) is an important commercial bio-diesel plant species and is being advocated for development of waste and dry land. the collar and root rot caused by lasiodiplodia theobromae is an important soil borne disease which causes considerable yield loss in this crop. in this study, the effects of culture media, temperature, photoperiod, carbon and nitrogen sources and ph on mycelial growth and pycnidial production were evaluated. among the growth media tested, potato dextrose ...201324640243
insights into the biosynthesis of 12-membered resorcylic acid lactones from heterologous production in saccharomyces cerevisiae.the phytotoxic fungal polyketides lasiodiplodin and resorcylide inhibit human blood coagulation factor xiiia, mineralocorticoid receptors, and prostaglandin biosynthesis. these secondary metabolites belong to the 12-membered resorcylic acid lactone (ral12) subclass of the benzenediol lactone (bdl) family. identification of genomic loci for the biosynthesis of lasiodiplodin from lasiodiplodia theobromae and resorcylide from acremonium zeae revealed collaborating iterative polyketide synthase (ipk ...201424597618
simultaneous quantification of phytohormones in fermentation extracts of botryodiplodia theobromae by liquid chromatography-electrospray tandem mass spectrometry.fermentation broth and biomass from three strains of botryodiplodia theobromae were characterized by high performance liquid chromatography-electrospray tandem mass spectrometry (hplc-esi-ms/ms) method, in order to quantify different phytohormones and to identify amino acid conjugates of jasmonic acid (ja) present in fermentation broths. a liquid-liquid extraction with ethyl acetate was used as sample preparation. the separation was carried out on a c18 reversed-phase hplc column followed by ana ...201424510403
carbohydrate metabolism changes in prunus persica gummosis infected with lasiodiplodia theobromae.peach gummosis represents a significant global disease of stone fruit trees and a major disease in the south peach production area of the yangtze river of china. in this study, the carbohydrate composition of peach shoots during infection by lasiodiplodia theobromae was examined. the expression of genes related to metabolic enzymes was also investigated. control wounded and noninoculated tissue, lesion tissue, and wounded and inoculated surrounding lesion tissue of peach shoots were analyzed. so ...201424283537
keratitis due to the wood saprobic ascomycete, auerswaldia lignicola (family botryosphaeriaceae), in a carpenter in india.keratitis due to auerswaldia lignicola in a 32-year-old indian male carpenter is described. at presentation, the patient reported persistent pain and tearing (left eye) in spite of topical antimicrobial therapy for more than 3 weeks. clinically, mycotic keratitis was suspected, and direct microscopy of corneal scrapings stained by lactophenol cotton blue and gram stains revealed broad septate hyphae. intensive topical antifungal therapy was then given for 15 days. the keratitis continued to prog ...201324158617
[identification of pathogen of aquilaria sinensis dieback disease].the research focused on identification the pathogen of aquilaria sinensis dieback disease and confirmation the function of inducing agarwood formation by fungi.201324010282
optimization of culture conditions for some identified fungal species and stability profile of α-galactosidase produced.microbial α-galactosidase preparations have implications in medicine and in the modification of various agricultural products as well. in this paper, four isolated fungal strains such as al-3, wf-3, wp-4 and cl-4 from rhizospheric soil identified as penicillium glabrum (al-3), trichoderma evansii (wf-3), lasiodiplodia theobromae (wp-4) and penicillium flavus (cl-4) based on their morphology and microscopic examinations, are screened for their potential towards α-galactosidases production. the cu ...201323424684
[bioremediation of pahs contaminated soil from beijing coking plant by lasiodiplodia theobromae].bioremediation of pahs contaminated soil from beijing coking plant was performed using a novel fungal strain lasiodiplodia theobromae (l. theobromae). moreover, enhanced bioremediation of pahs contaminated soil was investigated in the presence of different concentrations of tween 80 and hydroxypropyl-beta-cyclodextrin (hpcd). the correlation of the dynamics of enzyme activities during remediation and the degradation of pahs was analyzed. the results showed that the degradation rate of pahs incre ...201223213912
toxicological assessment of β-(1-->6)-glucan (lasiodiplodan) in mice during a 28-day feeding study by gavage.studies evaluating the toxicity caused by fungal exopolysaccharides of the β-(1-->6)-d-glucan type are rare. in this study, the toxicological effects of sub-chronic treatments with lasiodiplodan (β-(1-->6)-d-glucan from lasiodiplodia theobromae mmpi) were evaluated in mice through the assessment of biochemical, hematological, and histopathological alterations. thirty-two mice (16 male, 16 female) were used in this study divided in two groups; one group received lasiodiplodan (50 mg/kg body weigh ...201223208465
catalytic asymmetric synthesis of butane diacetal-protected (4s,5s)-dihydroxycyclohexen-1-one and use in natural product synthesis.due to the lack of availability of unnatural (+)-quinic acid as a starting material, a 6-step synthesis of butane diacetal-protected (4s,5s)-dihydroxycyclohexen-1-one (formally derived from (+)-quinic acid) has been devised. the key catalytic asymmetric step involves a chiral co-salen-catalysed epoxide ring-opening reaction. (4s,5s)-dihydroxycyclohexen-1-one was utilised in the synthesis of two cyclohexenone natural products isolated from the mycelia of lasiodiplodia theobromae.201222930235
one-pot synthesis of novel isoindoline-1,3-dione derivatives bearing 1,2,4-triazole moiety and their preliminary biological evaluation.a series of novel isoindoline-1,3-diones containing 1,2,4-triazole moiety were synthesized via a one-pot reaction. bioassay indicated that compounds 33, 35, 37 and 39 exhibited much higher activities against botryodiplodia theobromae than commercial fungicide triadimefon at the dosage of 150 mg/l. most interestingly, compounds 36, 37 and 45 displayed much stronger antitumor activities against four human cell lines than positive control fluorouracil. particularly, compound 37 had four-fold improv ...201222809558
lasiodiplodia theobromae keratitis: a case report and review of literature.a case report and review of literature is reported of a rare case of fungal keratitis from eastern india. a 32-year-old woman with a history of vegetative trauma presented with keratitis in left eye. microbiological examination of corneal scraping showed refractile hyphae with aseptate branching filaments and black pigmented colonies on multiple solid agar medium. organism was identified from culture using d1/d2 region of lsu (large sub unit: 28s rdna)-based molecular technique. pcr amplified a ...201222544631
lasiodiplodan, an exocellular (1→6)-β-d: -glucan from lasiodiplodia theobromae mmpi: production on glucose, fermentation kinetics, rheology and anti-proliferative activity.lasiodiplodan, an exopolysaccharide of the (1→6)-β-d: -glucan type, is produced by lasiodiplodia theobromae mmpi when grown under submerged culture on glucose. the objective of this study was to evaluate lasiodiplodan production by examining the effects of carbon (glucose, fructose, maltose, sucrose) and nitrogen sources (kno(3), (nh(4))(2)so(4), urea, yeast extract, peptone), its production in shake flasks compared to a stirred-tank bioreactor, and to study the rheology of lasiodiplodan, and la ...201222399240
improved cellulase production by botryosphaeria rhodina from opefb at low level moisture condition through statistical optimization.the response surface method was applied in this study to improve cellulase production from oil palm empty fruit bunch (opefb) by botryosphaeria rhodina. an experimental design based on a two-level factorial was employed to screen the significant environmental factors for cellulase production. the locally isolated fungus botryosphaeria rhodina was cultivated on opefb under solid-state fermentation (ssf). from the analysis of variance (anova), the initial moisture content, amount of substrate, and ...201222394064
lasiodiplodia theobromae is a mycoparasite of a powdery mildew pathogen.powdery mildews on over 40 plants in bangalore were screened during july-december of 2003~2008. isolates from mycoparasitised oidium caesalpiniacearum of bauhinia purpurea comprised lasiodiplodia theobromae, in addition to ampelomyces quisqualis. koch's postulates were satisfied to establish the mycoparasitism of l. theobromae. this is the first report that l. theobromae acts as a mycoparasite of a powdery mildew.200923983554
novel cyclohexene compound from lasiodiplodia theobromae ifo 31059.a novel cyclohexene compound (1), which is structurally related to theobroxide (2), was isolated from a culture filtrate of the fungus, lasiodiplodia theobromae ifo 31059. the potato micro-tuber-inducing activity of this compound was observed at a concentration of 10(-3) m in the medium, whereas theobroxide (2) showed its activity at 10(-5) m.199827392405
Displaying items 201 - 220 of 220