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inventory of antidiabetic plants in selected districts of lagos state, nigeria.this study reports an ethnobotanical survey by means of semi-structured questionnaire of medicinal plants in five districts of lagos state of nigeria reputed for the treatment of diabetes. 100 respondents from the predominantly yoruba tribe mostly males (76%) were knowledgeable in traditional treatment of diabetes. about half of the respondents with 20-30 years experience in treating diabetes used mainly herbs (96%) and have developed effective and easily recognised diagnostic tools. 92% of diab ...200919013225
a promising anticancer and antimalarial component from the leaves of bidens pilosa.bidens pilosa is used in folk medicine for various applications due to the presence of polyacetylenes, flavonoids, terpenoids, phenylpropanoids and others. bioactivity-guided fractionation of different extracts of b. pilosa leaf showed potential in vitro anticancer and antimalarial activity and led to the identification of a potential marker compound, phenyl-1,3,5-heptatriyne. erythrocyte osmotic fragility experiments revealed the various extracts as well as the marker component's toxicity profi ...200919031368
anti-hyperglycemic effects and mechanism of bidens pilosa water extract.bidens pilosa has traditionally been used as an anti-diabetic phytomedicine. however, its alleged benefits and mechanism remain elusive. this study aimed to evaluate the effect and action of bidens pilosa water extract on type 2 diabetes.200919162158
isolation and identification of a potent antimalarial and antibacterial polyacetylene from bidens pilosa.diseases caused by malaria parasites and pathogenic bacteria were thought to be on the brink of eradication in the 1950-1960s, but they have once again become a serious threat to mankind as a result of the appearance of multidrug resistant strains. the spread of these multidrug resistant organisms has prompted a worldwide search for new classes of effective antimalarial and antibacterial drugs. natural products have been recognized as highly important candidates for this purpose. our attention h ...200919263339
a sticktight flea removed from the cheek of a two-year-old boy from los angeles.species-level identification of an ectoparasite often requires outside expertise. patients are increasingly turning to the internet for medical information, in part to gain access to experts. we present a case of a flea identified after contact was made between a patient's father and the authors via an insect-related forum on the internet. the flea had been attached for 12 hours without inducing symptoms before it was removed. the specimen was identified as a sticktight flea ectoparasites in the ...200919281709
full-length sequence analysis of a distinct isolate of bidens mottle virus infecting sunflower in taiwan.the full-length genome of a potyvirus, previously known as sunflower chlorotic spot virus isolate sf-1 (scsv-sf-1) which causes novel symptoms on sunflowers (helianthus annuus), was sequenced and analyzed. the genome of scsv-sf-1 is 9,741 nucleotides long, encoding a polyprotein of 3,071 amino acids containing the consensus motifs of potyviruses. sequence comparison revealed that the 3'-terminus of scsv-sf-1 shared over 96% similarities with isolates of bidens mottle virus (bimov). however, scsv ...200919308314
constituents of cajanus cajan (l.) millsp., moringa oleifera lam., heliotropium indicum l. and bidens pilosa l. from nigeria.the essential oils of four plant species from nigeria have been extracted by hydrodistillation and analyzed by gc and gc-ms. the oils of cajanus cajan were comprised of sesquiterpenes (92.5%, 81.2% and 94.3% respectively in the leaves, stem and seeds). the major compounds identified were alpha-himachalene (9.0-11.5%), beta-himachalene (8.0-11.0%), gamma-himachalene (6.9-8.1%), alpha-humulene (7.1-8.7%) and alpha-copaene (4.5-5.6%). however, monoterpenoid compounds (81.8%) dominated the oil of mo ...200919476009
effects of bidens pilosa l. var. radiata scherff treated with enzyme on histamine-induced contraction of guinea pig ileum and on histamine release from mast cells.the medical mechanism against type i allergies is to block the release or production of chemical mediators from mast cells or to block the h(1)-receptor signaling. we previously reported that the anti-allergic action of the dry powder from bidens pilosa l. var. radiata scherff treated with the enzyme cellulosine (emmbp) was dependent on the inhibition of histamine release from mast cells. here, we investigate that the effect of fractions in emmbp on the histamine-induced contraction in guinea pi ...200919602852
anti-diabetic properties of three common bidens pilosa variants in taiwan.bidens pilosa l. var. radiata (bpr), b. pilosa l. var. pilosa (bpp), and b. pilosa l. var. minor (bpm) are common variants of a plant often used as a folk remedy for diabetes in taiwan. however, the three variants are often misidentified and little is known about their relative anti-diabetic efficacy and chemical composition. in this paper, we have first developed a method based on gc-ms and cluster analysis with visualization to assist in rapidly determining the taxonomy of these three bidens v ...200919683775
an acqueous extract of bidens pilosa l. protects liver from cholestatic disease: experimental study in young rats.to test the hepatoprotective effect of water extract from bidens pilosa l. (bpe) in cholestatic liver disease induced by ligature and resection of the common bile ducts (lrbd) in young rats.200919851686
joint effects of arsenic and cadmium on plant growth and metal bioaccumulation: a potential cd-hyperaccumulator and as-excluder bidens pilosa l.joint effects of arsenic (as) and cadmium (cd) on the growth of bidens pilosa l. and its uptake and accumulation of as and cd were investigated using the field pot-culture experiment. the results showed that single cd (<or=25 mg kg(-1)) and as (<or=50 mg kg(-1)) treatments could promote the growth of b. pilosa, resulting in 34.5-104.4% and 21.0-43.0%, respectively, increase in the dry biomass of shoots while compared with that under the control conditions. however, under the co-contamination of ...200919070954
[characteristics of cadmium tolerance and bioaccumulation of bidens pilosa l. seedlings].bidens pilosa l. has been identified as a newly found cd-hyperaccumulator. in the present study, the characteristics of its cd tolerance (growth response and physiological and biochemical characteristics) and accumulation were examined. the results showed that low cd treatments (< or =32 mg/kg) could enhance plant growth, the dry biomass of shoot and root increased by 32.4%-44.7% and 29.1%-57.6%, respectively, at cd concentrations 8-32 mg/kg when compared with the control. the shoot dry biomass ...200919968126
[observation on therapeutic effect of runmushu oral liquid in treating xerophthalmia in postmenopausal women].to objectively evaluate the therapeutic effect and safety of runmushu oral liquid (rms) for the treatment of xerophthalmia in postmenopausal women.200919852302
differential growth response to arbuscular mycorrhizal fungi and plant density in two wild plants belonging to contrasting functional types.the effect of arbuscular mycorrhizal fungi (amf) on plant growth was examined in two wild plant species belonging to contrasting functional types: an annual forb (bidens pilosa, asteraceae) and a deciduous shrub (acacia caven, fabaceae) at three contrasting plant densities (one, two, and three individuals per pot). amf had a slightly negative effect on b. pilosa when the species grew in isolation while they positively affected a. caven. positive effects of amf on shoot mass of a. caven decreased ...200919444488
cadmium tolerance and accumulation characteristics of bidens pilosa l. as a potential cd-hyperaccumulator.recently, researchers are becoming interested in using hyperaccumulators for decontamination of heavy metal polluted soils, whereas few species that hyperaccumulate cadmium (cd) has been identified in the plant kingdom. in this study, the physiological mechanisms at the seedling stage and growth responses and cd uptake and accumulation at flowering and mature stages of bidens pilosa l. under cd treatments were investigated. at the seedling stage, when soil cd was lower than 16mgkg(-1), the plant ...200918513866
season variations for metallic elements compositions study in plant bidens pilosa l. var. radiate sch. in central taiwan.the possibility of using bidens pilosa l. var. radiate sch leaves as environmental indicators of metallic element pollution has been investigated. samples were analyzed with respect to the following pollutants: zn, mn, cu, ni, pb, cd, cr, fe, ca, and mg by using inductively coupled plasma atomic emission spectrometry. the results obtained on the metallic elements had the following average composition order: ca > mg > fe, mn > zn > cu > ni > pb > cr > cd for plant b. pilosa l. var. radiate sch. a ...201019685152
effects of bidens pilosa l. var. radiata scherff on experimental gastric lesion.bidens pilosa l. var. radiata scherff: (bp) is a plant used as a traditional folk medicine. bp, cultivated with only green manure on miyako island, okinawa prefecture, was processed to powder and is referred to as mmbp. we have reported that mmbp has antioxidant, anti-inflammatory, and anti-allergy properties. in this study, we investigated the effects of mmbp on several experimental gastric lesions induced by hcl/etoh, a non-steroidal anti-inflammatory drug, or cold-restraint stress, comparing ...201020526746
polyacetylenes and flavonoids from the aerial parts of bidens pilosa.bidens pilosa is used in various folk medicines such as antimalarial, antibacterial, blood pressure-lowering, and antihyperglycemic agents. phytochemical investigation of the aerial parts of this plant yielded 10 polyacetylenes and 9 flavonoids, including four new polyacetylenes (5, 7- 9) and one new chalcone glucoside (11). the molecular structures of the isolated compounds were elucidated by comprehensive spectroscopic analysis.201020108176
botryorhodines a-d, antifungal and cytotoxic depsidones from botryosphaeria rhodina, an endophyte of the medicinal plant bidens pilosa.an endophytic fungus (botryosphaeria rhodina) was isolated from the stems of the medicinal plant bidens pilosa (asteraceae) that is known for its anti-inflammatory, antiseptic and antifungal effects. the ethyl acetate extract of the fungal isolate exhibits significant antifungal activity as well as potent cytotoxic and antiproliferative effects against several cancer cell lines. activity-guided fractionation resulted in the isolation of a complex of four depsidones, botryorhodines a-d and the au ...201019913264
screening of medicinal plants against leishmania amazonensis.leishmaniasis is a widespread tropical infection caused by different species of leishmania protozoa. there is no immunoprophylaxis (vaccination) available for leishmania infections and conventional treatments are unsatisfactory; therefore antileishmanial drugs are urgently needed. natural products are attractive due to their structural diversity.201020731558
anti-adult t-cell leukemia effects of bidens pilosa.we evaluated the effects of bidens pilosa, a plant found in tropical and subtropical regions, and investigated the molecular pathways responsible for the anti-adult t-cell leukemia (atl) effect. water extracts of b. pilosa had growth suppressive effects on human t-cell leukemia virus type 1 (htlv-1)-infected t-cell lines and atl cells. b. pilosa extracts arrested cells in g1 cell cycle and induced apoptosis of htlv-1-infected t-cell lines. b. pilosa extracts inhibited also the phosphorylation of ...201121318218
brazilian bidens pilosa linné yields fraction containing quercetin-derived flavonoid with free radical scavenger activity and hepatoprotective effects.bidens pilosa is a plant used by amazonian and asian folks for some hepatopathies. the hydroethanol crude extract and three fractions were assessed for antioxidant and hepatoprotective effects. higher levels of scavenger activity on the 1,1-diphenyl-2-picrylhydrazyl radical, inhibition of deoxyribose oxidation and lipid peroxidation in vitro were detected for the ethyl acetate fraction (ic(50)~4.3-32.3 µg/ml) followed by the crude extract (ic(50)~14.2-98.0 µg/ml). the ethyl acetate fraction, aga ...201121526045
the current status of fleas according to environmental changes in some governorates in egypt.a preliminary survey of domestic rodent and their fleas was carried out in different environmental governorates (ismailia, dakahlia, el-fayoum, north sinai and matrouh), egypt. flea index (number of flea/rodent) and percentage frequency of different flea species were recorded in spring (2009- 2010). the main rodent species found were the norway rat, rattus norvegicus, the grey-bellied rat, rattus rattus alexandrinus, the white- bellied rat, rattus rattus frugivorus, the house mouse, mus musculus ...201121634253
uterine contraction induced by tanzanian plants used to induce abortion.ethnopharmacological relevance: women in tanzania use plants to induce abortion. it is not known whether the plants have an effect. aims of study: collect data on plant use in relation to induced abortion and test the effect of plant extracts on uterine contraction. methods: during interviews with traditional birth attendants and nurses, plants were identified. cumulative doses of plant extracts were added to rat uterine tissue in an organ bath, and the force and frequency of contractions record ...201121645605
External parasites of raptors (Falconiformes and Strigiformes): identification in an ex situ population from Mexico.Raptorial birds harbor a variety of ectoparasites and the mayority of them are host specific. The aim of this study was to identify the ectoparasites of captive birds of prey from Mexico, as well as to verify their impact in the health of infested birds. Raptorial birds were confiscated and kept in captivity at the Centro de Investigación y Conservación de Vida Silvestre (CIVS) in Los Reyes La Paz, Mexico State. Seventy-four birds of prey (66 Falconiformes and eigth Strigiformes) of 15 species w ...201122017130
field studies on dominant rodents and the efficacy of certain insecticides to their fleas in dakahlia governorate, egypt.a preliminary survey of domestic rodent and the efficacy of bendiocarb, diazinon and pirimiphos-methyl insecticides to their fleas were carried out in dakahlia governorates (aga, meet-ghamr, el-senbellawen, temi el-amded, beni-abed, dekernes, nabarow, talkha, menia el-nasr and el-kordy). rodent index (number of rodent/trap) and percentage frequency of drodent species were recorded from october 2010 to may 2011. the main rodent species found were the norway rat, rattus norvegicus, the grey-bellie ...201121980770
effects of drugs of plant origin on the development of the immune response.the effects of extracts from licorice (glycyrrhisa glabra), great nettle (urtica dioica), common burdock (arctium lappa), and bur marigold (bidens tripartite) on the humoral and cellular immune response and nonspecific resistance in mice were studied. burdock and bur marigold extracts stimulated the humoral immune response, nettle and licorice extracts stimulated cellular response and nonspecific resistance, their effects being superior to those of pharmacopoeial echinacea purpurea tincture.201122238748
characterization and risk assessment of polychlorinated biphenyls in soils and vegetations near an electronic waste recycling site, south china.this study aimed at identifying the levels of pcbs generated from e-waste recycling, and their potential impacts on the soils and vegetations as well. the σpcbs concentrations in soil and plant samples ranged from 7.4 to 4000 ng g(-1) and from 6.7 to 1500 ng g(-1), respectively. for the plant samples, chrysanthemum coronarium l. from vegetable field and the wild plant bidens pilosa l. from the burning site showed relatively higher pcb concentrations than other species. for the soil samples, the ...201121813154
the first total synthesis of cytopiloyne, an anti-diabetic, polyacetylenic glucoside.the first total synthesis of cytopiloyne 1, a novel bioactive polyacetylenic glucoside isolated from the extract of bidens pilosa, is described. the structure of cytopiloyne was determined to be 2-β-d-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne by using various spectroscopic methods, but the chirality of the polyyne moiety was unknown. herein, the convergent synthesis of two diastereomers of cytopiloyne by starting from commercially available 4-(2-hydroxyethyl)-2,2-dimethyl-1,3-diozolan ...201121681841
compilation of secondary metabolites from bidens pilosa l.bidens pilosa l. is a cosmopolitan annual herb, known for its traditional use in treating various diseases and thus much studied for the biological activity of its extracts, fractions and isolated compounds. polyacetylenes and flavonoids, typical metabolite classes in the bidens genus, predominate in the phytochemistry of b. pilosa. these classes of compounds have great taxonomic significance. in the asteraceae family, the acetylene moiety is widely distributed in the heliantheae tribe and some ...201121270729
hplc method development and validation of cytotoxic agent phenyl-heptatriyne in bidens pilosa with ultrasonic-assisted cloud point extraction and preconcentration.extraction and pre-concentration of a bioactive marker compound, phenyl-1,3,5-heptatriyne from bidens pilosa, prior to hplc has been demonstrated using both organic and ecofriendly solvents. non-ionic surfactants, viz. triton x-100, triton x-114 and genapol x-80, were used for extraction. no back-extraction or liquid chromatographic steps were required to remove the target phytochemical from the surfactant-rich extractant phase. the optimized cloud point extraction procedure has been shown to be ...201120812202
what's eating you? the sticktight flea (echidnophaga gallinacea). 201222611740
effect on blood pressure of a dietary supplement containing traditional medicinal plants of côte d'ivoire.a medicinal composition containing salt (sodium chloride) is given as a traditional dietary supplement to hypertensive patients (tdshp) in côte d'ivoire. it consists of whole plant of bidens pilosa (asteraceae) and fresh leaves of moringa oleifera (moringaceae).201222480886
the impact of herbal drug use on adverse drug reaction profiles of patients on antiretroviral therapy in zimbabwe.background. the main objective was to determine the impact of herbal drug use on adverse drug reactions in patients on antiretroviral therapy (art). methodology. patients receiving first-line art from the national roll-out program participated in this cross-sectional study. participants were interviewed and a data collection sheet was used to collect information from the corresponding medical record. results. the majority (98.2%) of participants were using at least one herbal drug together with ...201222506106
behavioural response of the malaria vector anopheles gambiae to host plant volatiles and synthetic blends.sugar feeding is critical for survival of malaria vectors and, although discriminative plant feeding previously has been shown to occur in anopheles gambiae s.s., little is known about the cues mediating attraction to these plants. in this study, we investigated the role of olfaction in an. gambiae discriminative feeding behaviour.201223069316
efficacy of bidens pilosa extract against herpes simplex virus infection in vitro and in vivo.the development of strains of herpes simplex virus (hsv) resistant to drugs has been reported among the immunocompromised patients. thus, there is a need to develop new therapeutic agents for hsv infections. we evaluated the anti-hsv activity of bidens pilosa (b. pilosa), a tropical weed, in tissue culture cells and a mouse model. b. pilosa extract showed potent virucidal activity. it inhibited plaque formation and suppressed virus yield in vero and raw 264.7 cells infected with hsv-1 and hsv-2. ...201222474501
experimental researches on acute toxicity of a bidens tripartita extract in mice - preliminary investigations.plants take up an important place in traditional medicine and scientific research confirmed properties about their use as alternative therapy. bidens tripartita, commonly known as three-lobe beggarticks, three-part beggarticks, trifid bur-marigold, is a flowering plant in the genus bidens, family compositae, subfamily asteroideae. evaluation of the chemical composition of this plant has revealed the presence of flavonoids, xanthophylls, volatile oil, acetylene and polyacetylene, sterols, aurones ...201223700917
plants used as antidiabetics in popular medicine in rio grande do sul, southern brazil.plants are widely as antidiabetics. the study of these plants is essential because many of them may have undesirable effects, such as acute or chronic toxicity; or their use may even delay or discourage the adoption of the proper and effective treatment.201222079795
screen of chinese weed species for cadmium tolerance and accumulation characteristics.the cadmium (cd) tolerance and metal-accumulation characteristics of 29 species (18 families) of weed were studied by using outdoor pot-culture experiments. the results of this screening showed that bidens pilosa and kalimeris integrifolia (both asteraceae) expressed some properties that are characteristic of cd hyperaccumulators. in 10 mg/kg cd-spiked soil, they accumulated a good deal of cd in shoots (28 and 25 mg/kg dw, respectively) with high cd enrichment factors (efs; concentration in plan ...201319260234
bidens pilosa l. (asteraceae): botanical properties, traditional uses, phytochemistry, and pharmacology.there are 230 to 240 known bidens species. among them, bidens pilosa is a representative perennial herb, globally distributed across temperate and tropical regions. b. pilosa has been traditionally used in foods and medicines without obvious adverse effects. despite significant progress in phytochemical and biological analyses of b. pilosa over the past few years, comprehensive and critical reviews of this plant are anachronistic or relatively limited in scope. the present review aims to summari ...201323935661
[antimalarial activity and cytotoxicity of hydroalcoholic extracts from six plant species used in cuban traditional medicine].malaria is the most important parasitic disease for global health. lack of the structural diversity in current antimalarials demands the urgent search for new therapeutic alternatives. the plants have shown their potential to provide effective antimalarials, therefore, a large sample of cuban medicinal plants is being studied.201323437537
[interspecific association of companion species in artemisia annua community in southwest of china].the interspecific association of companion species in artemisia annua community in 48 region of southwest china was analyzed by variance analysis, chi2-test and association indices. the total related variance ratio among species in a. annua community was 2.05. among 45 species pairs of 10 main species in the community, only 4 pairs showed significant negative correlations. chi2 test, pc, oi, di and ac values indicated pairs 1-8 (a. annua- a. lactiflora), 1-9 (a. annua- setaria viridis) and 1-10 ...201323724672
investigation of the extracts from bidens pilosa linn. var. radiata sch. bip. for antioxidant activities and cytotoxicity against human tumor cells.the aim of this study was to evaluate antioxidant activities and cytotoxicity against human tumor cell lines of extracts from bidens pilosa linn. var. radiata sch. bip. (bp). total phenolic and flavonoid contents of the extracts were determined by ultraviolet spectrophotometry. furthermore, the antioxidant properties of different polarity fractions extracted from bp were evaluated using dpph and abts radical scavenging test and frap assay. the ethyl acetate fraction (ee-bp) showed the highest an ...201322382861
invasive congeners are unlikely to hybridize with native hawaiian bidens (asteraceae). 201323733530
comparison of the nutritive value and biological activities of the acetone, methanol and water extracts of the leaves of bidens pilosa and chenopodium album.a resurgence of interest has developed in wild vegetables for their possible medicinal values in diets. wild plant species provide minerals, fibre, vitamins and essential fatty acids and enhance taste and color in diets. for this reason, the nutritional, phytochemical, antioxidant and antibacterial activities of the acetone, methanol and water extracts of the leaves of bidens pilosa and chenopodium album were investigated. the proximate analysis showed that the leaves of the plants contained app ...201321485705
preliminary phytochemical screening and molluscicidal activity of the aqueous extract of bidens pilosa linné (asteraceae) in subulina octona (mollusca, subulinidade).the aim of this study was to establish reference concentrations (lc₅₀ e lc₉₀) of aqueous extracts of bidens pilosa on the land snail subulina octona, in order to assess the changes caused by 24 and 48 h exposure to the sublethal concentration regarding species' fecundity, hatchability and in offspring produced after exposure to confirm the presence of tannins, saponins and flavonoids in this plant species. eggs newly hatched and 30 day-old snails were exposed to sublethal concentration, calculat ...201324141417
[chemical constituents in whole herb of bidens pilosa var. radiata].to study the chemical constituents of bidens pilosa var. radiata.201324010324
decrease of reactive oxygen species and reciprocal increase of nitric oxide in human dermal endothelial cells by bidens pilosa extract: a possible explanation of its beneficial effect on livedo vasculopathy. 201323819986
effect of floral sources on the antioxidant, antimicrobial, and anti-inflammatory activities of honeys in taiwan.we evaluated the antioxidant, antibacterial, and anti-inflammatory activities of honey made from different floral sources, including the medicinal herb bidens pilosa, fruit trees, dimocarpus longan, litchi chinensis, and citrus maxima, the taiwanese endemic plant aglaia formosana, and a multifloral forest. the total phenolic and flavonoid contents of the honey made from b. pilosa were significantly higher than those of the other honeys. the honey from b. pilosa also had significantly greater sca ...201323561193
wild leafy vegetables consumed in buhera district of zimbabwe and their phenolic compounds content.a questionnaire was used to gather information on the wild leafy vegetables consumed. the phenolic concentrations were determined by the vanillin, butanol, and tannin binding assays. seventy-nine traditional vegetables were mentioned by the respondents and 20 of these were classified according to their species. the contents of flavonoids varied from 1.2 mg/g for cleome gynandra to 8.0 mg/g for bidens pilosa. the levels of proanthocyanidins ranged from 1.9 mg/g for lettuce to 11.2 mg/g for bidens ...201323445395
extraction of antioxidant components from bidens pilosa flowers and their uptake by human intestinal caco-2 cells.bidens pilosa l. var. radiata (bpr, asteraceae) is a commonly used folk medicine for treating various disorders such as diabetes, inflammation and hypertension. recent studies to determine its chemical composition have revealed three di-o-caffeoylquinic acids (dicqas) and three polyacetylene glucosides (pgas) to be among the major bioactive markers. to obtain the major compounds of these two chemical classes, the ethyl acetate fraction (em) obtained using liquid-liquid partition from the methano ...201323353127
n-butanol fraction of entada phaseoloides ethanol extract inhibits hepatocellular carcinoma hepg2 cell proliferation by inducing apoptosis.to screen for substances with inhibitory effects on the proliferation of hepatocellular carcinoma (hcc) hepg2 cell line from extracts of traditional chinese medicinal plants including heliciopsis lobata (merr.) sleum, bidens pilosa, entada phaseoloides, plantago major, and smilax, and unveil their mechanism of action.201424965399
a trade off between separation, detection and sustainability in liquid chromatographic fingerprinting.it is now recognized that analytical chemistry must also be a target for green principles, in particular chromatographic methods which typically use relatively large volumes of hazardous organic solvents. more generally, high performance liquid chromatography (hplc) is employed routinely for quality control of complex mixtures in various industries. acetonitrile and methanol are the most commonly used organic solvents in hplc, but they generate an impact on the environment and can have a negativ ...201424952659
medicinal plants used in malaria treatment by prometra herbalists in uganda.the aim of the survey was to document medicinal plants used in malaria treatment by prometra (promocion de la medicina tradicional amazonica) traditional medical practitioners (tmps) of uganda and for search of new antiplasmodial herbal medicines (hms) for further phytochemical analysis.201424928824
botanical, pharmacological, phytochemical, and toxicological aspects of the antidiabetic plant bidens pilosa l.bidens pilosa l. is an easy-to-grow, widespread, and palatable perennial on earth. hence, it has traditionally been used as foods and medicines without noticeable adverse effects. despite significant advancement in chemical and biological studies of b. pilosa over the past few years, comprehensive and critical reviews on its anti-diabetic properties are missing. the present review is to summarize up-to-date information on the pharmacology, phytochemistry, and toxicology of b. pilosa, in regard t ...201424616740
the role of pentacyclic triterpenoids in the allelopathic effects of alstonia scholaris.alstonia scholaris is a tropical evergreen tree native to south and southeast asia. alstonia forests frequently lack understory species. however, potential mechanisms-particularly the allelochemicals involved-remain unclear. in the present study, we identified allelochemicals of a. scholaris, and clarified the role of allelopathic substances from a. scholaris in interactions with neighboring plants. we showed that the leaves, litter, and soil from a. scholaris inhibited growth of bidens pilosa-a ...201424390624
analgesic and antiinflammatory activities of the ethyl acetate fraction of bidens pilosa (asteraceae).bidens pilosa is an asteraceae widely used in traditional medicine for the treatment of various ailments including pain and inflammation. the present work was undertaken to assess the analgesic and antiinflammatory properties of the ethyl acetate fraction of methylene chloride/methanol (1:1) extract of leaves of bidens pilosa at the gradual doses of 50, 100 and 200 mg/kg in mice and rats, respectively. the analgesic properties of bidens pilosa were investigated using the acetic acid writhing, ho ...201424242914
[decomposition of herbaceous species in reservoir riparian region of three gorges reservoir under flooding condition].a total of 10 annuals and perennials of herbaceous species were investigated in reservoir riparian region of three gorges reservoir. the correlations between the plants' nutrient release rate and the substrate composition and structural matter were studied under flooding condition. the decomposition rates of different species differed substantially, with the maximum of alternanthera philoxeroides (decomposition rate constant k = 0.0228 d(-1)) and the minimum of microstegium vimineum (k = 0.0029 ...201425509072
performance of bemisia tabaci (genn.) biotype b (hemiptera: aleyrodidae) on weeds.bemisia tabaci (genn.) biotype b (hemiptera: aleyrodidae) is regarded as a pest with a large number of hosts, including crops and weeds. the performance of this whitefly on seven weeds was evaluated in order to identify the most suitable host. the following weeds that are very common in intense agricultural areas in the state of são paulo, brazil, were selected for this study: spurge (euphorbia heterophylla), beggarticks (bidens pilosa), red tasselflower (emilia sonchifolia), small-flower galins ...201427194066
toxicity of six plant extracts and two pyridone alkaloids from ricinus communis against the malaria vector anopheles gambiae.the african malaria vector, anopheles gambiae s.s., is known to feed selectively on certain plants for sugar sources. however, the adaptive significance of this behaviour especially on how the extracts of such plants impact on the fitness of this vector has not been explored. this study determined the toxicity and larvicidal activity on this vector of extracts from six selected plants found in kenya and two compounds identified from ricinus communis: 3-carbonitrile-4-methoxy-n-methyl-2-pyridone ...201424996560
evaluation of antimicrobial and cytotoxic activities of plant extracts from southern minas gerais cerrado.the antimicrobial activity of plant hidroethanolic extracts on bacteria gram positive, gram negative, yeasts, mycobacterium tuberculosis h37 and mycobacterium bovis was evaluated by using the technique of agar diffusion and microdilution in broth. among the extracts evaluated by agar diffusion, the extract of bidens pilosa leaf presented the most expressive average of haloes of growth inhibition to the microorganisms, followed by the extract of b. pilosa flower, of eugenia pyriformis' leaf and s ...201424553603
total flavonoids of bidens bipinnata l. ameliorate experimental adjuvant-induced arthritis through induction of synovial apoptosis.bidens bipinnata are widely distributed in china, which have been widely used as a traditional chinese medicine. the aim of this study was to examine the effect of total flavonoids of bidens pilosa l. (tfb) on adjuvant arthritis (aa) and its possible mechanisms.201526669668
effect of bidens pilosa on infection and drug resistance of eimeria in chickens.extensive use of current anti-coccidial drugs together with drug resistance and residue has raised concerns about public health and poultry development. here, we studied the anti-coccidial properties of bidens pilosa. a phytochemical approach was developed for analysis of b. pilosa utilized as a feed additive. the protective effects of b. pilosa supplemented chicken diet were evaluated chickens infected with eimeria tenella. b. pilosa, at doses of 0.5%, 1% and 5% of the chicken diet, significant ...201525440995
medicinal plants used by a mbyá-guarani tribe against infections: activity on kpc-producing isolates and biofilm-forming bacteria.the traditional use of medicinal plants for treatment of infectious diseases by an indigenous mbyá-guarani tribe from south brazil was assessed by evaluating the antibiotic and antibiofilm activities against relevant bacterial pathogens. aqueous extracts from 10 medicinal plants were prepared according to indigenous mbyá-guarani traditional uses. to evaluate antibiotic (od600) and antibiofilm (crystal violet method) activities, pseudomonas aeruginosa atcc 27853, staphylococcus epidermidis atcc 3 ...201526749812
the invasive american weed parthenium hysterophorus can negatively impact malaria control in africa.the direct negative effects of invasive plant species on agriculture and biodiversity are well known, but their indirect effects on human health, and particularly their interactions with disease-transmitting vectors, remains poorly explored. this study sought to investigate the impact of the invasive neotropical weed parthenium hysterophorus and its toxins on the survival and energy reserves of the malaria vector anopheles gambiae. in this study, we compared the fitness of an. gambiae fed on thr ...201526367123
essential oils from ugandan aromatic medicinal plants: chemical composition and growth inhibitory effects on oral pathogens.the study assessed the growth inhibitory effects of essential oils extracted from ten ugandan medicinal plants (bidens pilosa, helichrysum odoratissimum, vernonia amygdalina, hoslundia opposita, ocimum gratissimum, cymbopogon citratus, cymbopogon nardus, teclea nobilis, zanthoxylum chalybeum, and lantana trifolia) used traditionally in the management of oral diseases against oral pathogens. chemical compositions of the oils were explored by gc-ms. inhibitory effects of the oils were assessed on ...201526170872
flow cytometry reveals that the rust fungus, uromyces bidentis (pucciniales), possesses the largest fungal genome reported--2489 mbp.among the eukaryotes, fungi have relatively small genomes (average of 44.2 mbp across 1850 species). the order pucciniales (basidiomycota) has the largest average genome size among fungi (305 mbp), and includes the two largest fungal genomes reported so far (puccinia chrysanthemi and gymnosporangium confusum, with 806.5 and 893.2 mbp, respectively). in this work, flow cytometry was employed to determine the genome size of the bidens pilosa rust pathogen, uromyces bidentis. the results obtained r ...201525784533
medicinal plants used to treat tb in ghana.the current study was designed to document medicinal plant species that are traditionally used to treat tuberculosis (tb) by ghanaian communities.201526972879
evaluation of two brazilian indigenous plants for phytostabilization and phytoremediation of copper-contaminated soils.indigenous plants have been grown naturally and vigorously in copper contaminated soils. thus, the aim of this study was to evaluate the phytoremediation ability of two indigenous plants naturally grown in two vineyard soils copper contaminated, and in a copper mining waste. however, it was evaluated the macro and micronutrient uptake and the potential of phytoremediation. so, a greenhouse study was carried out with bidens pilosa and plantago lanceolata in samples of vineyard soils (inceptisol a ...201526675903
evaluation of two brazilian indigenous plants for phytostabilization and phytoremediation of copper-contaminated soils.abstractindigenous plants have been grown naturally and vigorously in copper contaminated soils. thus, the aim of this study was to evaluate the phytoremediation ability of two indigenous plants naturally grown in two vineyard soils copper contaminated, and in a copper mining waste. however, it was evaluated the macro and micronutrient uptake and the potential of phytoremediation. so, a greenhouse study was carried out with bidens pilosa and plantago lanceolata in samples of vineyard soils (ince ...201526560649
mechanistic study of the phytocompound, 2- β -d-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in human t-cell acute lymphocytic leukemia cells by using combined differential proteomics and bioinformatics approaches.bidens pilosa, a medicinal herb worldwide, is rich in bioactive polyynes. in this study, by using high resolution 2-dimensional gel electrophoresis coupled with mass spectrometry analysis, as many as 2000 protein spots could be detected and those whose expression was specifically up- or downregulated in jurkat t cells responsive to the treatment with 2-β-d-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne (ghtt) can be identified. ghtt treatment can upregulate thirteen proteins involved in si ...201526557148
antiageing mechanisms of a standardized supercritical co 2 preparation of black jack (bidens pilosa l.) in human fibroblasts and skin fragments.the use of topical retinoids to treat skin disorders and ageing can induce local reactions, while oral retinoids are potent teratogens and produce several unwanted effects. this way, efforts to explore complementary care resources should be supported. based on this, we evaluate the antiageing effects of a supercritical co2 extract from bidens pilosa l. (bpe-co2a) containing a standardized multicomponent mixture of phytol, linolenic, palmitic, linoleic, and oleic acids. bpe-co2a was assessed for ...201525883669
bidens pilosa formulation improves blood homeostasis and β -cell function in men: a pilot study.b. pilosa has long been purported to have antidiabetes activity, but despite the advancement in phytochemistry and animal models of diabetes, no human clinical trials have been conducted to date. here, we evaluated the effect of a b. pilosa formulation on fasting blood glucose (fbg), fasting serum insulin, and glycosylated hemoglobin a1c (hba1c) in diabetic subjects. the b. pilosa formulation reduced the level of fbg and hba1c in diabetics but increased fasting serum insulin in healthy subjects. ...201525866541
effects of a native parasitic plant on an exotic invader decrease with increasing host age.understanding changes in the interactions between parasitic plants and their hosts in relation to ontogenetic changes in the hosts is crucial for successful use of parasitic plants as biological controls. we investigated growth, photosynthesis and chemical defences in different-aged bidens pilosa plants in response to infection by cuscuta australis. we were particularly interested in whether plant responses to parasite infection change with changes in the host plant age. compared with the non-in ...201525838325
isoquercitrin inhibits the progression of pancreatic cancer in vivo and in vitro by regulating opioid receptors and the mitogen-activated protein kinase signalling pathway.pancreatic cancer is a common malignant tumour that affects individuals worldwide. in recent years, the incidence and mortality rates of pancreatic cancer have continuously increased. currently, the primary clinical treatment methods for pancreatic cancer include surgical resection, chemotherapy and radiotherapy. however, these treatment methods rarely produce satisfactory therapeutic outcomes. extensive research has also proven that the effective components of several traditional chinese medici ...201525434366
tetraoxanes as a new class of efficient herbicides comparable with commercial products.several 1,2,4,5-tetraoxanes were synthesised, and their herbicidal activity was tested against weeds and compared with the activity of commercial herbicides glyphosate and imazethapyr.201525157959
changes in gametophyte physiology of pteris multifida induced by the leaf leachate treatment of the invasive bidens pilosa.in recent years, the response of fern gametophytes to environment has raised much attention. however, studies on the influence of plant invasion to fern gametophytes are scarce. allelopathy plays an important role in biological invasion. hence, it is necessary to study the allelopathic effects of invasive plants on fern gametophytes and elucidate the mechanisms by which invasive plants cause phytotoxicity. as one of the main invasive plants in china, bidens pilosa exhibits allelopathic effects o ...201626490937
assessment of the root system of brassica juncea (l.) czern. and bidens pilosa l. exposed to lead polluted soils using rhizobox systems.the purpose of this study was to compare the behavior of the root system of one of the most frequently cited species in phytoremediation indian mustard [brassica juncea (l.) czern.] and a representative perennial herb (bidens pilosa l.) native of argentina, for different concentrations of lead in soils through chemical and visualization techniques of the rhizosphere. lead polluted soils from the vicinity of a lead recycling plant in the locality of bouwer, were used in juxtaposed rhizobox system ...201626292209
novel platensimycin derivatives with herbicidal activity.faced with the need to develop herbicides with different modes of action on account of weed resistance to existing herbicides, the sesquiterpene lactones can be the starting point in the search for new bioactive compounds. lumisantonin and five novel amides have been evaluated against two monocotyledons and three dicotyledons.201625914183
herbal medicine use and linked suspected adverse drug reactions in a prospective cohort of ugandan inpatients.clinical history-taking can be employed as a standardized approach to elucidate the use of herbal medicines and their linked suspected adverse drug reactions (adrs) among hospitalized patients. we sought to identify herbal medicines nominated by ugandan inpatients; compare nomination rates by ward and gender; confirm the herbs' known pharmacological properties from published literature; and identify adrs linked to pre-admission use of herbal medicines.201627229463
prevalence of ectoparasites of indigenous chickens from dalahu region, kermanshah province, iran.ectoparasitism is an important factor associated with the poor production of indigenous chickens. the present study was undertaken to estimate the prevalence and ectoparasite diversity in indigenous chickens of the dalahu region in the western part of kermanshah province, iran.201627222329
endogenous trans-zeatin content in plants with different metal-accumulating ability: a field survey.a field survey was conducted to evaluate soil metal pollution and endogenous trans-zeatin content in the leaves of plants growing at six sites in a metal-polluted area located in gejiu, yunnan, china. five plant species were collected, and the physicochemical properties and concentrations of five metals in the soil were analyzed. the trans-zeatin content in plant leaves was measured by high-performance liquid chromatography. based on the nemerow pollution index, the six sites were classified int ...201627613625
data on the effect of cytopiloyne against listeria monocytogenes infection in mice.cytopiloyne (cp), a novel polyacetylene compound extracted from b. pilosa, shows a multi-bioactivity, including immunomodulatory and antidiabetes. here, we investigated the anti-listeria effect of cytopiloyne in mice by assessing mortality, clearance of l. monocytogenes, and pathology examination. the data presented herein are supplemental to our research article entitled "cytopiloyne, a polyacetylenic glucoside from bidens pilosa, acts as a novel anticandidial agent via regulation of macrophage ...201627761492
studies on bioactivity and secondary metabolites of crude extracts of bidens pilosa l. (asteraceae): a medicinal plant used in the transkei region of south africa.whole plant-parts of bidens pilosa were powdered and extracted in concentrated hexane, acetone, ethanol, methanol and water. the extracts were tested for antimicrobial activity against escherichia coli (25922), bacillus subtilis (atcc 6051), enterococcus faecalis (51299) staphylococcus aureus (atcc 29213) and pseudomonas aeruginosa (atcc127853), using standard microbiological techniques. active crude extracts were macerated in concentrated methanol and tested for secondary metabolites including ...201627166532
cytopiloyne, a polyacetylenic glucoside from bidens pilosa, acts as a novel anticandidal agent via regulation of macrophages.bidens pilosa, a tropical and sub-tropical herbal plant, is used as an ethnomedicine for bacterial infection or immune modulation in asia, america and africa. it has been demonstrated that cytopiloyne (cp), a bioactive polyacetylenic glucoside purified from b. pilosa, increases the percentage of macrophages in the spleen but the specific effects on macrophages remain unclear.201626924565
in vitro and in vivo anti-helicobacter activities of eryngium foetidum (apiaceae), bidens pilosa (asteraceae), and galinsoga ciliata (asteraceae) against helicobacter pylori.this study was performed to evaluate the antimicrobial activities of extracts of bidens pilosa, galinsoga ciliata, and eryngium foetidum against 6 clinical strains of helicobacter pylori in vitro and in vivo. broth microdilution method was used in vitro. in vivo, swiss mice were inoculated with h. pylori and divided into 5 groups; the control group received the vehicle and the four others received 125, 250, and 500 mg/kg of methanol extract of eryngium foetidum and ciprofloxacin (500 mg/kg) for ...201627631003
brain transcriptional profiles of male alternative reproductive tactics and females in bluegill sunfish.bluegill sunfish (lepomis macrochirus) are one of the classic systems for studying male alternative reproductive tactics (arts) in teleost fishes. in this species, there are two distinct life histories: parental and cuckolder, encompassing three reproductive tactics, parental, satellite, and sneaker. the parental life history is fixed, whereas individuals who enter the cuckolder life history transition from sneaker to satellite tactic as they grow. for this study, we used rnaseq to characterize ...201627907106
inhibiting mdsc differentiation from bone marrow with phytochemical polyacetylenes drastically impairs tumor metastasis.myeloid-derived suppressor cells (mdscs) are implicated in the promotion of tumor metastasis by protecting metastatic cancerous cells from immune surveillance and have thus been suggested as novel targets for cancer therapy. we demonstrate here that oral feeding with polyacetylenic glycosides (bp-e-f1) from the medicinal plant bidens pilosa effectively suppresses tumor metastasis and inhibits tumor-induced accumulation of granulocytic (g) mdscs, but does not result in body weight loss in a mouse ...201627857157
essential oils from ugandan medicinal plants: in vitro cytotoxicity and effects on il-1β-induced proinflammatory mediators by human gingival fibroblasts.the study investigated cytotoxicity of essential oils from four medicinal plants (bidens pilosa, ocimum gratissimum, cymbopogon nardus, and zanthoxylum chalybeum) on human gingival fibroblasts and their effects on proinflammatory mediators' secretion. cytotoxicity of essential oils was investigated using 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide assay. effects of essential oils at subcytotoxicity concentrations on interleukin- (il-) 6, il-8, and prostaglandin e2 (pge2) secre ...201627807462
the fate of the herbicide propanil in plants of the littoral zone of the three gorges reservoir (tgr), china.the anti-seasonal hydrology with 30m water fluctuations in the three gorges reservoir (tgr) of china attracts growing environmental and ecological concerns. we investigated the biotransformation of the herbicide propanil in plants dominating in the littoral zone of the tgr by applying the (14)c-ring-labeled herbicide into non-aseptic hydroponic plant systems (cynodon dactylon, nelumbo nucifera and bidens pilosa), aseptic plants (lemna minor and lemna gibba) and cell suspension cultures (c. dacty ...201627745669
antioxidant activities of essential oil of bidens pilosa (linn. var. radita) used for the preservation of food qualities in north cameroon.this study aimed to determine the total antioxidant capacity of the essential oil (eo) of leaves of bidens pilosa (linn. var. radita) used as protectant of stored grains in northern cameroon. eo was characterized by gc-fid, antioxidant activity (aa) was determined by combining: evaluation of radical-scavenging activity, reducing power (rp) and co-oxidation of β-carotene methods. tests were carried out on crude and stored eo kept for two weeks at 31.48 ± 2.88°c and 58.56 ± 6.78% relative humidity ...201627625769
the effect of the aqueous extract of bidens pilosa l. on androgen deficiency dry eye in rats.bidens pilosa l. (bp) is widely distributed in china and has been widely used as a traditional chinese medicine. the aim of this study was to examine the effect of the extract of bp on androgen deficiency dry eye and determine its possible mechanisms.201627337217
isoquercitrin inhibits bladder cancer progression in vivo and in vitro by regulating the pi3k/akt and pkc signaling pathways.bladder cancer is the most common malignancy of the urinary system and is also one of the 10 most common cancers of the human body. currently, clinical treatment of bladder cancer mainly utilizes partial or total cystectomy, supplemented by conventional chemotherapy. however, such treatment has not fully improved the prognosis of patients and is associated with various side effects. studies have found that flavonoids extracted from plants can be used in radiotherapy and chemotherapy for the prev ...201627177091
field trial of medicinal plant, bidens pilosa, against eimeriosis in broilers.eimeriosis is a severe protozoan disease in poultry. because of increasing concern about drug residue and drug resistance with the use of anticoccidial drugs, natural products are emerging as an alternative and complementary approach to control avian eimeriosis. our previous publication showed that feed supplemented with b. pilosa (bp) was effective at combating chicken eimeriosis in experimental settings. however, its efficacy against chicken eimeriosis under field conditions is not known. here ...201627098674
[protective effect of total flavones of bidens pilosa l. on iga1 induced injury of huvecs in henoch-schönlein purpura children patients].to explore the protective effect and mechanism of total flavones of bidens pilosa l. (tfb) on iga1 induced injury of venous endothelial cells in henoch-schönlein purpura (hsp) children patients. methods human umbilical venous endothelial cells (huvecs) were taken as subject. they were intervened by normal iga1 and hsp children patients' serum iga1, and added with different concentrations tfb at the same time. then they were divided into the blank control group, the normal control group, the hsp ...201627078994
bidens pilosa and its active compound inhibit adipogenesis and lipid accumulation via down-modulation of the c/ebp and pparγ pathways.obesity and its complications are a major global health problem. in this study, we investigated the anti-obesity effect and mechanism of an edible plant, bidens pilosa, and its active constituent. we first assessed the long-term effect of b. pilosa on body composition, body weight, blood parameters in icr mice. we observed that it significantly decreased fat content and increased protein content in icr mice. next, we verified the anti-obesity effect of b. pilosa in ob/ob mice. it effectively and ...201627063434
separation and identification of phenolic compounds in bidens pilosa l. by ultra high performance liquid chromatography with quadrupole time-of-flight mass spectrometry.a validated method based on ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry was established to separate and identify phenolic compounds in bidens pilosa l. mass spectrometry experiments were performed both in positive and negative ion modes. a total of 35 compounds were detected, and 26 phenolic compounds were unequivocally identified or tentatively assigned based on retention time, maximum uv absorption, molecular formula, and fragments. the ultr ...201627004754
auxin effects on pb phytoextraction from polluted soils by tegetes minuta l. and bidens pilosa l.: extractive power of their root exudates.the principal impediment for pb uptake by plants is the casparian strip in roots. it prevents metals reaching the xylem, thereby hampering translocation to the aerial organs. in the root apices, young root cells have thin cell walls and the casparian strip is not completely developed, which could facilitate pb uptake by roots at these vulnerable points. however, as the phytotoxic effects of pb reduce root growth and enhance suberization, entry of pb into the plant is avoided. we propose that the ...201626954477
photosynthetic electron-transfer reactions in the gametophyte of pteris multifida reveal the presence of allelopathic interference from the invasive plant species bidens pilosa.to date, the response of the fern gametophyte to its environment has received considerable attention. however, studies on the influence of plant invasion on the fern gametophyte are fewer. allelopathy has been hypothesized to play an important role in biological invasion. hence, it is necessary to study the allelopathy of invasive plant species to the fern gametophyte and elucidate the mechanisms by which invasive plants cause phytotoxicity. as one of the main invasive plants in china, bidens pi ...201626954232
herbicidal and cytotoxic constituents from aralia armata (wall.) seem.two new triterpenoids, 3β-hydroxyoleana-11,13(18)-diene-28,30-dioic acid (1) and 3-oxooleana-11,13(18)-diene-28,30-dioic acid (2), one novel triterpenoid glycoside, 3β-o-(6'-o-methyl-β-d-glucuronopyranosyl)oleana-11,13(18)-dien-28-oic acid (3) along with six known compounds (4 - 9) were isolated from the stem bark of aralia armata (wall.) seem. their structures were elucidated through extensive spectroscopic methods. the herbicidal activities of these compounds against bidens pilosa l., an invas ...201626948515
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