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biochemical changes in terminal root galls caused by an ectoparasitic nematode, longidorus africanus: amino acids.the amino acids of terminal root galls caused by longidorus africanus on bur marigold (bidens tripartita l.) and grapevine (vitis vinifera l.) were studied. the galled roots of bur marigold contained 73% more cell-wall protein and 184% more free amino acids. the main changes among the free amino acids of the galled tissue were a large increase (1900%) in proline and a decrease in aspartic acid (56%) compared with the respective check tissue. hydroxyproline decreased in the wall protein fraction ...197119322388
differential growth response to arbuscular mycorrhizal fungi and plant density in two wild plants belonging to contrasting functional types.the effect of arbuscular mycorrhizal fungi (amf) on plant growth was examined in two wild plant species belonging to contrasting functional types: an annual forb (bidens pilosa, asteraceae) and a deciduous shrub (acacia caven, fabaceae) at three contrasting plant densities (one, two, and three individuals per pot). amf had a slightly negative effect on b. pilosa when the species grew in isolation while they positively affected a. caven. positive effects of amf on shoot mass of a. caven decreased ...200919444488
constituents of cajanus cajan (l.) millsp., moringa oleifera lam., heliotropium indicum l. and bidens pilosa l. from nigeria.the essential oils of four plant species from nigeria have been extracted by hydrodistillation and analyzed by gc and gc-ms. the oils of cajanus cajan were comprised of sesquiterpenes (92.5%, 81.2% and 94.3% respectively in the leaves, stem and seeds). the major compounds identified were alpha-himachalene (9.0-11.5%), beta-himachalene (8.0-11.0%), gamma-himachalene (6.9-8.1%), alpha-humulene (7.1-8.7%) and alpha-copaene (4.5-5.6%). however, monoterpenoid compounds (81.8%) dominated the oil of mo ...200919476009
first records of two mealybug species in brazil and new potential pests of papaya and coffee.five mealybug (hemiptera: pseudococcidae) plant pest species: dysmicoccus grassii (leonardi), ferrisia malvastra (mcdaniel), ferrisia virgata (cockerell), phenacoccus tucumanus granara de willink, and pseudococcus elisae borchsenius are recorded for the first time in the state of espírito santo, brazil. these are the first records of d. grassii in brazil, from papaya (carica papaya, caricaceae), and from coffee (coffea canephora, rubiaceae). ferrisia malvastra is also newly recorded in brazil, w ...200619537975
effects of bidens pilosa l. var. radiata scherff treated with enzyme on histamine-induced contraction of guinea pig ileum and on histamine release from mast cells.the medical mechanism against type i allergies is to block the release or production of chemical mediators from mast cells or to block the h(1)-receptor signaling. we previously reported that the anti-allergic action of the dry powder from bidens pilosa l. var. radiata scherff treated with the enzyme cellulosine (emmbp) was dependent on the inhibition of histamine release from mast cells. here, we investigate that the effect of fractions in emmbp on the histamine-induced contraction in guinea pi ...200919602852
anti-diabetic properties of three common bidens pilosa variants in taiwan.bidens pilosa l. var. radiata (bpr), b. pilosa l. var. pilosa (bpp), and b. pilosa l. var. minor (bpm) are common variants of a plant often used as a folk remedy for diabetes in taiwan. however, the three variants are often misidentified and little is known about their relative anti-diabetic efficacy and chemical composition. in this paper, we have first developed a method based on gc-ms and cluster analysis with visualization to assist in rapidly determining the taxonomy of these three bidens v ...200919683775
season variations for metallic elements compositions study in plant bidens pilosa l. var. radiate sch. in central taiwan.the possibility of using bidens pilosa l. var. radiate sch leaves as environmental indicators of metallic element pollution has been investigated. samples were analyzed with respect to the following pollutants: zn, mn, cu, ni, pb, cd, cr, fe, ca, and mg by using inductively coupled plasma atomic emission spectrometry. the results obtained on the metallic elements had the following average composition order: ca > mg > fe, mn > zn > cu > ni > pb > cr > cd for plant b. pilosa l. var. radiate sch. a ...201019685152
an acqueous extract of bidens pilosa l. protects liver from cholestatic disease: experimental study in young rats.to test the hepatoprotective effect of water extract from bidens pilosa l. (bpe) in cholestatic liver disease induced by ligature and resection of the common bile ducts (lrbd) in young rats.200919851686
[observation on therapeutic effect of runmushu oral liquid in treating xerophthalmia in postmenopausal women].to objectively evaluate the therapeutic effect and safety of runmushu oral liquid (rms) for the treatment of xerophthalmia in postmenopausal women.200919852302
botryorhodines a-d, antifungal and cytotoxic depsidones from botryosphaeria rhodina, an endophyte of the medicinal plant bidens pilosa.an endophytic fungus (botryosphaeria rhodina) was isolated from the stems of the medicinal plant bidens pilosa (asteraceae) that is known for its anti-inflammatory, antiseptic and antifungal effects. the ethyl acetate extract of the fungal isolate exhibits significant antifungal activity as well as potent cytotoxic and antiproliferative effects against several cancer cell lines. activity-guided fractionation resulted in the isolation of a complex of four depsidones, botryorhodines a-d and the au ...201019913264
[characteristics of cadmium tolerance and bioaccumulation of bidens pilosa l. seedlings].bidens pilosa l. has been identified as a newly found cd-hyperaccumulator. in the present study, the characteristics of its cd tolerance (growth response and physiological and biochemical characteristics) and accumulation were examined. the results showed that low cd treatments (< or =32 mg/kg) could enhance plant growth, the dry biomass of shoot and root increased by 32.4%-44.7% and 29.1%-57.6%, respectively, at cd concentrations 8-32 mg/kg when compared with the control. the shoot dry biomass ...200919968126
[identification characters of leaf venation of bidens pilosa with its confused herb bidens pilosa var. radiata].to study the leaf venation characteristics of bidens pilosa and b. pilosa var. radiata and establish an identification method.200920069891
polyacetylenes and flavonoids from the aerial parts of bidens pilosa.bidens pilosa is used in various folk medicines such as antimalarial, antibacterial, blood pressure-lowering, and antihyperglycemic agents. phytochemical investigation of the aerial parts of this plant yielded 10 polyacetylenes and 9 flavonoids, including four new polyacetylenes (5, 7- 9) and one new chalcone glucoside (11). the molecular structures of the isolated compounds were elucidated by comprehensive spectroscopic analysis.201020108176
in vivo and in vitro effects of bidens pilosa l. (asteraceae) leaf aqueous and ethanol extracts on primed-oestrogenized rat uterine muscle.bidens pilosa l. is an asteraceae growing in tropical zones, and traditionally utilized worldwide in herbal medicine. the present work is based on its traditional use during child birth as a labour facilitator. in vivo tests of acute toxicity showed a weak toxic effect for both extracts but the toxicity of the ethanol extract (ld(50)=6.15 g/kg) was upper than that of the aqueous extract (ld(50)=12.30 g/kg). the three-days uterotrophic assay on immature mice showed body weight gain followed by a ...200720162059
control of the sticktight flea on chickens. 194620341280
effects of bidens pilosa l. var. radiata scherff on experimental gastric lesion.bidens pilosa l. var. radiata scherff: (bp) is a plant used as a traditional folk medicine. bp, cultivated with only green manure on miyako island, okinawa prefecture, was processed to powder and is referred to as mmbp. we have reported that mmbp has antioxidant, anti-inflammatory, and anti-allergy properties. in this study, we investigated the effects of mmbp on several experimental gastric lesions induced by hcl/etoh, a non-steroidal anti-inflammatory drug, or cold-restraint stress, comparing ...201020526746
screening of medicinal plants against leishmania amazonensis.leishmaniasis is a widespread tropical infection caused by different species of leishmania protozoa. there is no immunoprophylaxis (vaccination) available for leishmania infections and conventional treatments are unsatisfactory; therefore antileishmanial drugs are urgently needed. natural products are attractive due to their structural diversity.201020731558
hplc method development and validation of cytotoxic agent phenyl-heptatriyne in bidens pilosa with ultrasonic-assisted cloud point extraction and preconcentration.extraction and pre-concentration of a bioactive marker compound, phenyl-1,3,5-heptatriyne from bidens pilosa, prior to hplc has been demonstrated using both organic and ecofriendly solvents. non-ionic surfactants, viz. triton x-100, triton x-114 and genapol x-80, were used for extraction. no back-extraction or liquid chromatographic steps were required to remove the target phytochemical from the surfactant-rich extractant phase. the optimized cloud point extraction procedure has been shown to be ...201120812202
joyce after flaubert: the cuckold as imperfect physician, the writer as physiologist.although joyce was not as familiar with the practice and theory of medicine as was gustave flaubert, this article argues that, through flaubert's legacy, joyce's writing was influenced by the french school of medical thought. several aspects of flaubert's style and narration-what has been dubbed his "medical realism"-were taken up by joyce: the artist's impersonal perspective, the precision of descriptions, and the materialist attack against romanticism, as well as the irony built into the narra ...200820836269
compilation of secondary metabolites from bidens pilosa l.bidens pilosa l. is a cosmopolitan annual herb, known for its traditional use in treating various diseases and thus much studied for the biological activity of its extracts, fractions and isolated compounds. polyacetylenes and flavonoids, typical metabolite classes in the bidens genus, predominate in the phytochemistry of b. pilosa. these classes of compounds have great taxonomic significance. in the asteraceae family, the acetylene moiety is widely distributed in the heliantheae tribe and some ...201121270729
anti-adult t-cell leukemia effects of bidens pilosa.we evaluated the effects of bidens pilosa, a plant found in tropical and subtropical regions, and investigated the molecular pathways responsible for the anti-adult t-cell leukemia (atl) effect. water extracts of b. pilosa had growth suppressive effects on human t-cell leukemia virus type 1 (htlv-1)-infected t-cell lines and atl cells. b. pilosa extracts arrested cells in g1 cell cycle and induced apoptosis of htlv-1-infected t-cell lines. b. pilosa extracts inhibited also the phosphorylation of ...201121318218
comparison of the nutritive value and biological activities of the acetone, methanol and water extracts of the leaves of bidens pilosa and chenopodium album.a resurgence of interest has developed in wild vegetables for their possible medicinal values in diets. wild plant species provide minerals, fibre, vitamins and essential fatty acids and enhance taste and color in diets. for this reason, the nutritional, phytochemical, antioxidant and antibacterial activities of the acetone, methanol and water extracts of the leaves of bidens pilosa and chenopodium album were investigated. the proximate analysis showed that the leaves of the plants contained app ...201321485705
brazilian bidens pilosa linné yields fraction containing quercetin-derived flavonoid with free radical scavenger activity and hepatoprotective effects.bidens pilosa is a plant used by amazonian and asian folks for some hepatopathies. the hydroethanol crude extract and three fractions were assessed for antioxidant and hepatoprotective effects. higher levels of scavenger activity on the 1,1-diphenyl-2-picrylhydrazyl radical, inhibition of deoxyribose oxidation and lipid peroxidation in vitro were detected for the ethyl acetate fraction (ic(50)~4.3-32.3 µg/ml) followed by the crude extract (ic(50)~14.2-98.0 µg/ml). the ethyl acetate fraction, aga ...201121526045
the current status of fleas according to environmental changes in some governorates in egypt.a preliminary survey of domestic rodent and their fleas was carried out in different environmental governorates (ismailia, dakahlia, el-fayoum, north sinai and matrouh), egypt. flea index (number of flea/rodent) and percentage frequency of different flea species were recorded in spring (2009- 2010). the main rodent species found were the norway rat, rattus norvegicus, the grey-bellied rat, rattus rattus alexandrinus, the white- bellied rat, rattus rattus frugivorus, the house mouse, mus musculus ...201121634253
uterine contraction induced by tanzanian plants used to induce abortion.ethnopharmacological relevance: women in tanzania use plants to induce abortion. it is not known whether the plants have an effect. aims of study: collect data on plant use in relation to induced abortion and test the effect of plant extracts on uterine contraction. methods: during interviews with traditional birth attendants and nurses, plants were identified. cumulative doses of plant extracts were added to rat uterine tissue in an organ bath, and the force and frequency of contractions record ...201121645605
the first total synthesis of cytopiloyne, an anti-diabetic, polyacetylenic glucoside.the first total synthesis of cytopiloyne 1, a novel bioactive polyacetylenic glucoside isolated from the extract of bidens pilosa, is described. the structure of cytopiloyne was determined to be 2-β-d-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne by using various spectroscopic methods, but the chirality of the polyyne moiety was unknown. herein, the convergent synthesis of two diastereomers of cytopiloyne by starting from commercially available 4-(2-hydroxyethyl)-2,2-dimethyl-1,3-diozolan ...201121681841
characterization and risk assessment of polychlorinated biphenyls in soils and vegetations near an electronic waste recycling site, south china.this study aimed at identifying the levels of pcbs generated from e-waste recycling, and their potential impacts on the soils and vegetations as well. the σpcbs concentrations in soil and plant samples ranged from 7.4 to 4000 ng g(-1) and from 6.7 to 1500 ng g(-1), respectively. for the plant samples, chrysanthemum coronarium l. from vegetable field and the wild plant bidens pilosa l. from the burning site showed relatively higher pcb concentrations than other species. for the soil samples, the ...201121813154
field studies on dominant rodents and the efficacy of certain insecticides to their fleas in dakahlia governorate, egypt.a preliminary survey of domestic rodent and the efficacy of bendiocarb, diazinon and pirimiphos-methyl insecticides to their fleas were carried out in dakahlia governorates (aga, meet-ghamr, el-senbellawen, temi el-amded, beni-abed, dekernes, nabarow, talkha, menia el-nasr and el-kordy). rodent index (number of rodent/trap) and percentage frequency of drodent species were recorded from october 2010 to may 2011. the main rodent species found were the norway rat, rattus norvegicus, the grey-bellie ...201121980770
External parasites of raptors (Falconiformes and Strigiformes): identification in an ex situ population from Mexico.Raptorial birds harbor a variety of ectoparasites and the mayority of them are host specific. The aim of this study was to identify the ectoparasites of captive birds of prey from Mexico, as well as to verify their impact in the health of infested birds. Raptorial birds were confiscated and kept in captivity at the Centro de Investigación y Conservación de Vida Silvestre (CIVS) in Los Reyes La Paz, Mexico State. Seventy-four birds of prey (66 Falconiformes and eigth Strigiformes) of 15 species w ...201122017130
plants used as antidiabetics in popular medicine in rio grande do sul, southern brazil.plants are widely as antidiabetics. the study of these plants is essential because many of them may have undesirable effects, such as acute or chronic toxicity; or their use may even delay or discourage the adoption of the proper and effective treatment.201222079795
effects of drugs of plant origin on the development of the immune response.the effects of extracts from licorice (glycyrrhisa glabra), great nettle (urtica dioica), common burdock (arctium lappa), and bur marigold (bidens tripartite) on the humoral and cellular immune response and nonspecific resistance in mice were studied. burdock and bur marigold extracts stimulated the humoral immune response, nettle and licorice extracts stimulated cellular response and nonspecific resistance, their effects being superior to those of pharmacopoeial echinacea purpurea tincture.201122238748
investigation of the extracts from bidens pilosa linn. var. radiata sch. bip. for antioxidant activities and cytotoxicity against human tumor cells.the aim of this study was to evaluate antioxidant activities and cytotoxicity against human tumor cell lines of extracts from bidens pilosa linn. var. radiata sch. bip. (bp). total phenolic and flavonoid contents of the extracts were determined by ultraviolet spectrophotometry. furthermore, the antioxidant properties of different polarity fractions extracted from bp were evaluated using dpph and abts radical scavenging test and frap assay. the ethyl acetate fraction (ee-bp) showed the highest an ...201322382861
efficacy of bidens pilosa extract against herpes simplex virus infection in vitro and in vivo.the development of strains of herpes simplex virus (hsv) resistant to drugs has been reported among the immunocompromised patients. thus, there is a need to develop new therapeutic agents for hsv infections. we evaluated the anti-hsv activity of bidens pilosa (b. pilosa), a tropical weed, in tissue culture cells and a mouse model. b. pilosa extract showed potent virucidal activity. it inhibited plaque formation and suppressed virus yield in vero and raw 264.7 cells infected with hsv-1 and hsv-2. ...201222474501
effect on blood pressure of a dietary supplement containing traditional medicinal plants of côte d'ivoire.a medicinal composition containing salt (sodium chloride) is given as a traditional dietary supplement to hypertensive patients (tdshp) in côte d'ivoire. it consists of whole plant of bidens pilosa (asteraceae) and fresh leaves of moringa oleifera (moringaceae).201222480886
the impact of herbal drug use on adverse drug reaction profiles of patients on antiretroviral therapy in zimbabwe.background. the main objective was to determine the impact of herbal drug use on adverse drug reactions in patients on antiretroviral therapy (art). methodology. patients receiving first-line art from the national roll-out program participated in this cross-sectional study. participants were interviewed and a data collection sheet was used to collect information from the corresponding medical record. results. the majority (98.2%) of participants were using at least one herbal drug together with ...201222506106
what's eating you? the sticktight flea (echidnophaga gallinacea). 201222611740
behavioural response of the malaria vector anopheles gambiae to host plant volatiles and synthetic blends.sugar feeding is critical for survival of malaria vectors and, although discriminative plant feeding previously has been shown to occur in anopheles gambiae s.s., little is known about the cues mediating attraction to these plants. in this study, we investigated the role of olfaction in an. gambiae discriminative feeding behaviour.201223069316
extraction of antioxidant components from bidens pilosa flowers and their uptake by human intestinal caco-2 cells.bidens pilosa l. var. radiata (bpr, asteraceae) is a commonly used folk medicine for treating various disorders such as diabetes, inflammation and hypertension. recent studies to determine its chemical composition have revealed three di-o-caffeoylquinic acids (dicqas) and three polyacetylene glucosides (pgas) to be among the major bioactive markers. to obtain the major compounds of these two chemical classes, the ethyl acetate fraction (em) obtained using liquid-liquid partition from the methano ...201323353127
[antimalarial activity and cytotoxicity of hydroalcoholic extracts from six plant species used in cuban traditional medicine].malaria is the most important parasitic disease for global health. lack of the structural diversity in current antimalarials demands the urgent search for new therapeutic alternatives. the plants have shown their potential to provide effective antimalarials, therefore, a large sample of cuban medicinal plants is being studied.201323437537
wild leafy vegetables consumed in buhera district of zimbabwe and their phenolic compounds content.a questionnaire was used to gather information on the wild leafy vegetables consumed. the phenolic concentrations were determined by the vanillin, butanol, and tannin binding assays. seventy-nine traditional vegetables were mentioned by the respondents and 20 of these were classified according to their species. the contents of flavonoids varied from 1.2 mg/g for cleome gynandra to 8.0 mg/g for bidens pilosa. the levels of proanthocyanidins ranged from 1.9 mg/g for lettuce to 11.2 mg/g for bidens ...201323445395
effect of floral sources on the antioxidant, antimicrobial, and anti-inflammatory activities of honeys in taiwan.we evaluated the antioxidant, antibacterial, and anti-inflammatory activities of honey made from different floral sources, including the medicinal herb bidens pilosa, fruit trees, dimocarpus longan, litchi chinensis, and citrus maxima, the taiwanese endemic plant aglaia formosana, and a multifloral forest. the total phenolic and flavonoid contents of the honey made from b. pilosa were significantly higher than those of the other honeys. the honey from b. pilosa also had significantly greater sca ...201323561193
experimental researches on acute toxicity of a bidens tripartita extract in mice - preliminary investigations.plants take up an important place in traditional medicine and scientific research confirmed properties about their use as alternative therapy. bidens tripartita, commonly known as three-lobe beggarticks, three-part beggarticks, trifid bur-marigold, is a flowering plant in the genus bidens, family compositae, subfamily asteroideae. evaluation of the chemical composition of this plant has revealed the presence of flavonoids, xanthophylls, volatile oil, acetylene and polyacetylene, sterols, aurones ...201223700917
[interspecific association of companion species in artemisia annua community in southwest of china].the interspecific association of companion species in artemisia annua community in 48 region of southwest china was analyzed by variance analysis, chi2-test and association indices. the total related variance ratio among species in a. annua community was 2.05. among 45 species pairs of 10 main species in the community, only 4 pairs showed significant negative correlations. chi2 test, pc, oi, di and ac values indicated pairs 1-8 (a. annua- a. lactiflora), 1-9 (a. annua- setaria viridis) and 1-10 ...201323724672
invasive congeners are unlikely to hybridize with native hawaiian bidens (asteraceae). 201323733530
decrease of reactive oxygen species and reciprocal increase of nitric oxide in human dermal endothelial cells by bidens pilosa extract: a possible explanation of its beneficial effect on livedo vasculopathy. 201323819986
bidens pilosa l. (asteraceae): botanical properties, traditional uses, phytochemistry, and pharmacology.there are 230 to 240 known bidens species. among them, bidens pilosa is a representative perennial herb, globally distributed across temperate and tropical regions. b. pilosa has been traditionally used in foods and medicines without obvious adverse effects. despite significant progress in phytochemical and biological analyses of b. pilosa over the past few years, comprehensive and critical reviews of this plant are anachronistic or relatively limited in scope. the present review aims to summari ...201323935661
[chemical constituents in whole herb of bidens pilosa var. radiata].to study the chemical constituents of bidens pilosa var. radiata.201324010324
preliminary phytochemical screening and molluscicidal activity of the aqueous extract of bidens pilosa linné (asteraceae) in subulina octona (mollusca, subulinidade).the aim of this study was to establish reference concentrations (lc₅₀ e lc₉₀) of aqueous extracts of bidens pilosa on the land snail subulina octona, in order to assess the changes caused by 24 and 48 h exposure to the sublethal concentration regarding species' fecundity, hatchability and in offspring produced after exposure to confirm the presence of tannins, saponins and flavonoids in this plant species. eggs newly hatched and 30 day-old snails were exposed to sublethal concentration, calculat ...201324141417
control of a symmetry-breaking process in the course of the morphogenesis of plantlets of bidens pilosa l.a mechanism involving transport, storage and retrieval of a symmetry-breaking message controls the relative growth rate of the cotyledonary buds of plantlets of bidens pilosa l. the asymmetry was induced by administering a few needle pricks to one cotyledon of each plant. the storage of the symmetry-breaking message was independent of the number of pricks ("all or nothing" process) and irreversible. however, various treatments could render the plants either able to retrieve the stored symmetry-b ...199124194158
analgesic and antiinflammatory activities of the ethyl acetate fraction of bidens pilosa (asteraceae).bidens pilosa is an asteraceae widely used in traditional medicine for the treatment of various ailments including pain and inflammation. the present work was undertaken to assess the analgesic and antiinflammatory properties of the ethyl acetate fraction of methylene chloride/methanol (1:1) extract of leaves of bidens pilosa at the gradual doses of 50, 100 and 200 mg/kg in mice and rats, respectively. the analgesic properties of bidens pilosa were investigated using the acetic acid writhing, ho ...201424242914
the role of pentacyclic triterpenoids in the allelopathic effects of alstonia scholaris.alstonia scholaris is a tropical evergreen tree native to south and southeast asia. alstonia forests frequently lack understory species. however, potential mechanisms-particularly the allelochemicals involved-remain unclear. in the present study, we identified allelochemicals of a. scholaris, and clarified the role of allelopathic substances from a. scholaris in interactions with neighboring plants. we showed that the leaves, litter, and soil from a. scholaris inhibited growth of bidens pilosa-a ...201424390624
evaluation of allelopathic potential of dominant herbaceous species in a coffee plantation.several shaded coffee plantations in coatepec, veracruz (mexico) are characterized by a dense cover of herbaceous vegetation mainly dominated by species from the commelinaceae which protect the soil from erosion and presumably contribute to regulating the abundance of other weeds. to detect their alleopathic potential, leachates from fresh, air-dried, or oven-dried plants and litter collected during different months of the year were tested uponbrassica campestris, bidens pilosa, andrumex sp. see ...198324407802
evaluation of antimicrobial and cytotoxic activities of plant extracts from southern minas gerais cerrado.the antimicrobial activity of plant hidroethanolic extracts on bacteria gram positive, gram negative, yeasts, mycobacterium tuberculosis h37 and mycobacterium bovis was evaluated by using the technique of agar diffusion and microdilution in broth. among the extracts evaluated by agar diffusion, the extract of bidens pilosa leaf presented the most expressive average of haloes of growth inhibition to the microorganisms, followed by the extract of b. pilosa flower, of eugenia pyriformis' leaf and s ...201424553603
botanical, pharmacological, phytochemical, and toxicological aspects of the antidiabetic plant bidens pilosa l.bidens pilosa l. is an easy-to-grow, widespread, and palatable perennial on earth. hence, it has traditionally been used as foods and medicines without noticeable adverse effects. despite significant advancement in chemical and biological studies of b. pilosa over the past few years, comprehensive and critical reviews on its anti-diabetic properties are missing. the present review is to summarize up-to-date information on the pharmacology, phytochemistry, and toxicology of b. pilosa, in regard t ...201424616740
medicinal plants used in malaria treatment by prometra herbalists in uganda.the aim of the survey was to document medicinal plants used in malaria treatment by prometra (promocion de la medicina tradicional amazonica) traditional medical practitioners (tmps) of uganda and for search of new antiplasmodial herbal medicines (hms) for further phytochemical analysis.201424928824
a trade off between separation, detection and sustainability in liquid chromatographic fingerprinting.it is now recognized that analytical chemistry must also be a target for green principles, in particular chromatographic methods which typically use relatively large volumes of hazardous organic solvents. more generally, high performance liquid chromatography (hplc) is employed routinely for quality control of complex mixtures in various industries. acetonitrile and methanol are the most commonly used organic solvents in hplc, but they generate an impact on the environment and can have a negativ ...201424952659
n-butanol fraction of entada phaseoloides ethanol extract inhibits hepatocellular carcinoma hepg2 cell proliferation by inducing apoptosis.to screen for substances with inhibitory effects on the proliferation of hepatocellular carcinoma (hcc) hepg2 cell line from extracts of traditional chinese medicinal plants including heliciopsis lobata (merr.) sleum, bidens pilosa, entada phaseoloides, plantago major, and smilax, and unveil their mechanism of action.201424965399
toxicity of six plant extracts and two pyridone alkaloids from ricinus communis against the malaria vector anopheles gambiae.the african malaria vector, anopheles gambiae s.s., is known to feed selectively on certain plants for sugar sources. however, the adaptive significance of this behaviour especially on how the extracts of such plants impact on the fitness of this vector has not been explored. this study determined the toxicity and larvicidal activity on this vector of extracts from six selected plants found in kenya and two compounds identified from ricinus communis: 3-carbonitrile-4-methoxy-n-methyl-2-pyridone ...201424996560
in vitro screening antibacterial activity of bidens pilosa linné and annona crassiflora mart. against oxacillin resistant staphylococcus aureus (orsa) from the aerial environment at the dental clinic.currently multiresistant staphylococcus aureus is one common cause of infections with high rates of morbidity and mortality worldwide, which directs scientific endeavors in search for novel antimicrobials. in this study, nine extracts from bidens pilosa (root, stem, flower and leaves) and annona crassiflora (rind fruit, stem, leaves, seed and pulp) were obtained with ethanol: water (7:3, v/v) and their in vitro antibacterial activity evaluated through both the agar diffusion and broth microdilut ...025076435
tetraoxanes as a new class of efficient herbicides comparable with commercial products.several 1,2,4,5-tetraoxanes were synthesised, and their herbicidal activity was tested against weeds and compared with the activity of commercial herbicides glyphosate and imazethapyr.201525157959
isoquercitrin inhibits the progression of pancreatic cancer in vivo and in vitro by regulating opioid receptors and the mitogen-activated protein kinase signalling pathway.pancreatic cancer is a common malignant tumour that affects individuals worldwide. in recent years, the incidence and mortality rates of pancreatic cancer have continuously increased. currently, the primary clinical treatment methods for pancreatic cancer include surgical resection, chemotherapy and radiotherapy. however, these treatment methods rarely produce satisfactory therapeutic outcomes. extensive research has also proven that the effective components of several traditional chinese medici ...201525434366
effect of bidens pilosa on infection and drug resistance of eimeria in chickens.extensive use of current anti-coccidial drugs together with drug resistance and residue has raised concerns about public health and poultry development. here, we studied the anti-coccidial properties of bidens pilosa. a phytochemical approach was developed for analysis of b. pilosa utilized as a feed additive. the protective effects of b. pilosa supplemented chicken diet were evaluated chickens infected with eimeria tenella. b. pilosa, at doses of 0.5%, 1% and 5% of the chicken diet, significant ...201525440995
[decomposition of herbaceous species in reservoir riparian region of three gorges reservoir under flooding condition].a total of 10 annuals and perennials of herbaceous species were investigated in reservoir riparian region of three gorges reservoir. the correlations between the plants' nutrient release rate and the substrate composition and structural matter were studied under flooding condition. the decomposition rates of different species differed substantially, with the maximum of alternanthera philoxeroides (decomposition rate constant k = 0.0228 d(-1)) and the minimum of microstegium vimineum (k = 0.0029 ...201425509072
flow cytometry reveals that the rust fungus, uromyces bidentis (pucciniales), possesses the largest fungal genome reported--2489 mbp.among the eukaryotes, fungi have relatively small genomes (average of 44.2 mbp across 1850 species). the order pucciniales (basidiomycota) has the largest average genome size among fungi (305 mbp), and includes the two largest fungal genomes reported so far (puccinia chrysanthemi and gymnosporangium confusum, with 806.5 and 893.2 mbp, respectively). in this work, flow cytometry was employed to determine the genome size of the bidens pilosa rust pathogen, uromyces bidentis. the results obtained r ...201525784533
effects of a native parasitic plant on an exotic invader decrease with increasing host age.understanding changes in the interactions between parasitic plants and their hosts in relation to ontogenetic changes in the hosts is crucial for successful use of parasitic plants as biological controls. we investigated growth, photosynthesis and chemical defences in different-aged bidens pilosa plants in response to infection by cuscuta australis. we were particularly interested in whether plant responses to parasite infection change with changes in the host plant age. compared with the non-in ...201525838325
bidens pilosa formulation improves blood homeostasis and β -cell function in men: a pilot study.b. pilosa has long been purported to have antidiabetes activity, but despite the advancement in phytochemistry and animal models of diabetes, no human clinical trials have been conducted to date. here, we evaluated the effect of a b. pilosa formulation on fasting blood glucose (fbg), fasting serum insulin, and glycosylated hemoglobin a1c (hba1c) in diabetic subjects. the b. pilosa formulation reduced the level of fbg and hba1c in diabetics but increased fasting serum insulin in healthy subjects. ...201525866541
antiageing mechanisms of a standardized supercritical co 2 preparation of black jack (bidens pilosa l.) in human fibroblasts and skin fragments.the use of topical retinoids to treat skin disorders and ageing can induce local reactions, while oral retinoids are potent teratogens and produce several unwanted effects. this way, efforts to explore complementary care resources should be supported. based on this, we evaluate the antiageing effects of a supercritical co2 extract from bidens pilosa l. (bpe-co2a) containing a standardized multicomponent mixture of phytol, linolenic, palmitic, linoleic, and oleic acids. bpe-co2a was assessed for ...201525883669
novel platensimycin derivatives with herbicidal activity.faced with the need to develop herbicides with different modes of action on account of weed resistance to existing herbicides, the sesquiterpene lactones can be the starting point in the search for new bioactive compounds. lumisantonin and five novel amides have been evaluated against two monocotyledons and three dicotyledons.201625914183
essential oils from ugandan aromatic medicinal plants: chemical composition and growth inhibitory effects on oral pathogens.the study assessed the growth inhibitory effects of essential oils extracted from ten ugandan medicinal plants (bidens pilosa, helichrysum odoratissimum, vernonia amygdalina, hoslundia opposita, ocimum gratissimum, cymbopogon citratus, cymbopogon nardus, teclea nobilis, zanthoxylum chalybeum, and lantana trifolia) used traditionally in the management of oral diseases against oral pathogens. chemical compositions of the oils were explored by gc-ms. inhibitory effects of the oils were assessed on ...201526170872
assessment of the root system of brassica juncea (l.) czern. and bidens pilosa l. exposed to lead polluted soils using rhizobox systems.the purpose of this study was to compare the behavior of the root system of one of the most frequently cited species in phytoremediation indian mustard [brassica juncea (l.) czern.] and a representative perennial herb (bidens pilosa l.) native of argentina, for different concentrations of lead in soils through chemical and visualization techniques of the rhizosphere. lead polluted soils from the vicinity of a lead recycling plant in the locality of bouwer, were used in juxtaposed rhizobox system ...201626292209
the invasive american weed parthenium hysterophorus can negatively impact malaria control in africa.the direct negative effects of invasive plant species on agriculture and biodiversity are well known, but their indirect effects on human health, and particularly their interactions with disease-transmitting vectors, remains poorly explored. this study sought to investigate the impact of the invasive neotropical weed parthenium hysterophorus and its toxins on the survival and energy reserves of the malaria vector anopheles gambiae. in this study, we compared the fitness of an. gambiae fed on thr ...201526367123
changes in gametophyte physiology of pteris multifida induced by the leaf leachate treatment of the invasive bidens pilosa.in recent years, the response of fern gametophytes to environment has raised much attention. however, studies on the influence of plant invasion to fern gametophytes are scarce. allelopathy plays an important role in biological invasion. hence, it is necessary to study the allelopathic effects of invasive plants on fern gametophytes and elucidate the mechanisms by which invasive plants cause phytotoxicity. as one of the main invasive plants in china, bidens pilosa exhibits allelopathic effects o ...201626490937
mechanistic study of the phytocompound, 2- β -d-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in human t-cell acute lymphocytic leukemia cells by using combined differential proteomics and bioinformatics approaches.bidens pilosa, a medicinal herb worldwide, is rich in bioactive polyynes. in this study, by using high resolution 2-dimensional gel electrophoresis coupled with mass spectrometry analysis, as many as 2000 protein spots could be detected and those whose expression was specifically up- or downregulated in jurkat t cells responsive to the treatment with 2-β-d-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne (ghtt) can be identified. ghtt treatment can upregulate thirteen proteins involved in si ...201526557148
evaluation of two brazilian indigenous plants for phytostabilization and phytoremediation of copper-contaminated soils.abstractindigenous plants have been grown naturally and vigorously in copper contaminated soils. thus, the aim of this study was to evaluate the phytoremediation ability of two indigenous plants naturally grown in two vineyard soils copper contaminated, and in a copper mining waste. however, it was evaluated the macro and micronutrient uptake and the potential of phytoremediation. so, a greenhouse study was carried out with bidens pilosa and plantago lanceolata in samples of vineyard soils (ince ...201526560649
total flavonoids of bidens bipinnata l. ameliorate experimental adjuvant-induced arthritis through induction of synovial apoptosis.bidens bipinnata are widely distributed in china, which have been widely used as a traditional chinese medicine. the aim of this study was to examine the effect of total flavonoids of bidens pilosa l. (tfb) on adjuvant arthritis (aa) and its possible mechanisms.201526669668
evaluation of two brazilian indigenous plants for phytostabilization and phytoremediation of copper-contaminated soils.indigenous plants have been grown naturally and vigorously in copper contaminated soils. thus, the aim of this study was to evaluate the phytoremediation ability of two indigenous plants naturally grown in two vineyard soils copper contaminated, and in a copper mining waste. however, it was evaluated the macro and micronutrient uptake and the potential of phytoremediation. so, a greenhouse study was carried out with bidens pilosa and plantago lanceolata in samples of vineyard soils (inceptisol a ...201526675903
medicinal plants used by a mbyá-guarani tribe against infections: activity on kpc-producing isolates and biofilm-forming bacteria.the traditional use of medicinal plants for treatment of infectious diseases by an indigenous mbyá-guarani tribe from south brazil was assessed by evaluating the antibiotic and antibiofilm activities against relevant bacterial pathogens. aqueous extracts from 10 medicinal plants were prepared according to indigenous mbyá-guarani traditional uses. to evaluate antibiotic (od600) and antibiofilm (crystal violet method) activities, pseudomonas aeruginosa atcc 27853, staphylococcus epidermidis atcc 3 ...201526749812
beneficial effect of bidens pilosa on body weight gain, food conversion ratio, gut bacteria and coccidiosis in chickens.in the interests of food safety and public health, plants and their compounds are now re-emerging as an alternative approach to treat gastrointestinal diseases in chickens. here, we studied the impact of the edible medicinal plant, b. pilosa, on growth performance, gut bacteria and coccidiosis in chickens. first, we found that b. pilosa significantly elevated body weight gain and lowered feed conversion ratio in chickens. next, we showed that b. pilosa reduced cecal damage as evidenced by increa ...201626765226
uptake and decomposition of the herbicide propanil in the plant bidens pilosa l. dominating in the yangtze three gorges reservoir (tgr), china.propanil (3',4'-dichloropropionanilide) is a selective post emergence herbicide for controlling broad leaf and grass weeds in rice (oryza sativa l.). after being taken up by plants, the fate of propanil in decomposing plant material is of particular importance to the phytoremediation of the environment. therefore, we investigated the biotransformation of propanil in the plant bidens pilosa under conditions close to those present in the three gorges reservoir (tgr), china. plants pre-treated with ...201626846318
cytopiloyne, a polyacetylenic glucoside from bidens pilosa, acts as a novel anticandidal agent via regulation of macrophages.bidens pilosa, a tropical and sub-tropical herbal plant, is used as an ethnomedicine for bacterial infection or immune modulation in asia, america and africa. it has been demonstrated that cytopiloyne (cp), a bioactive polyacetylenic glucoside purified from b. pilosa, increases the percentage of macrophages in the spleen but the specific effects on macrophages remain unclear.201626924565
effects of co-cropping bidens pilosa (l.) and tagetes minuta (l.) on bioaccumulation of pb in lactuca sativa (l.) growing in polluted agricultural soils.polluted agricultural soils are a serious problem for food safety, with phytoremediation being the most favorable alternative from the environmental perspective. however, this methodology is generally time-consuming and requires the cessation of agriculture. therefore, the purpose of this study was to evaluate two potential phytoextractor plants (the native species bidens pilosa and tagetes minuta) co-cropped with lettuce growing on agricultural lead-polluted soils. the concentrations of pb, as ...201626940382
herbicidal and cytotoxic constituents from aralia armata (wall.) seem.two new triterpenoids, 3β-hydroxyoleana-11,13(18)-diene-28,30-dioic acid (1) and 3-oxooleana-11,13(18)-diene-28,30-dioic acid (2), one novel triterpenoid glycoside, 3β-o-(6'-o-methyl-β-d-glucuronopyranosyl)oleana-11,13(18)-dien-28-oic acid (3) along with six known compounds (4 - 9) were isolated from the stem bark of aralia armata (wall.) seem. their structures were elucidated through extensive spectroscopic methods. the herbicidal activities of these compounds against bidens pilosa l., an invas ...201626948515
photosynthetic electron-transfer reactions in the gametophyte of pteris multifida reveal the presence of allelopathic interference from the invasive plant species bidens pilosa.to date, the response of the fern gametophyte to its environment has received considerable attention. however, studies on the influence of plant invasion on the fern gametophyte are fewer. allelopathy has been hypothesized to play an important role in biological invasion. hence, it is necessary to study the allelopathy of invasive plant species to the fern gametophyte and elucidate the mechanisms by which invasive plants cause phytotoxicity. as one of the main invasive plants in china, bidens pi ...201626954232
auxin effects on pb phytoextraction from polluted soils by tegetes minuta l. and bidens pilosa l.: extractive power of their root exudates.the principal impediment for pb uptake by plants is the casparian strip in roots. it prevents metals reaching the xylem, thereby hampering translocation to the aerial organs. in the root apices, young root cells have thin cell walls and the casparian strip is not completely developed, which could facilitate pb uptake by roots at these vulnerable points. however, as the phytotoxic effects of pb reduce root growth and enhance suberization, entry of pb into the plant is avoided. we propose that the ...201626954477
medicinal plants used to treat tb in ghana.the current study was designed to document medicinal plant species that are traditionally used to treat tuberculosis (tb) by ghanaian communities.201526972879
separation and identification of phenolic compounds in bidens pilosa l. by ultra high performance liquid chromatography with quadrupole time-of-flight mass spectrometry.a validated method based on ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry was established to separate and identify phenolic compounds in bidens pilosa l. mass spectrometry experiments were performed both in positive and negative ion modes. a total of 35 compounds were detected, and 26 phenolic compounds were unequivocally identified or tentatively assigned based on retention time, maximum uv absorption, molecular formula, and fragments. the ultr ...201627004754
bidens pilosa and its active compound inhibit adipogenesis and lipid accumulation via down-modulation of the c/ebp and pparγ pathways.obesity and its complications are a major global health problem. in this study, we investigated the anti-obesity effect and mechanism of an edible plant, bidens pilosa, and its active constituent. we first assessed the long-term effect of b. pilosa on body composition, body weight, blood parameters in icr mice. we observed that it significantly decreased fat content and increased protein content in icr mice. next, we verified the anti-obesity effect of b. pilosa in ob/ob mice. it effectively and ...201627063434
[protective effect of total flavones of bidens pilosa l. on iga1 induced injury of huvecs in henoch-schönlein purpura children patients].to explore the protective effect and mechanism of total flavones of bidens pilosa l. (tfb) on iga1 induced injury of venous endothelial cells in henoch-schönlein purpura (hsp) children patients. methods human umbilical venous endothelial cells (huvecs) were taken as subject. they were intervened by normal iga1 and hsp children patients' serum iga1, and added with different concentrations tfb at the same time. then they were divided into the blank control group, the normal control group, the hsp ...201627078994
field trial of medicinal plant, bidens pilosa, against eimeriosis in broilers.eimeriosis is a severe protozoan disease in poultry. because of increasing concern about drug residue and drug resistance with the use of anticoccidial drugs, natural products are emerging as an alternative and complementary approach to control avian eimeriosis. our previous publication showed that feed supplemented with b. pilosa (bp) was effective at combating chicken eimeriosis in experimental settings. however, its efficacy against chicken eimeriosis under field conditions is not known. here ...201627098674
studies on bioactivity and secondary metabolites of crude extracts of bidens pilosa l. (asteraceae): a medicinal plant used in the transkei region of south africa.whole plant-parts of bidens pilosa were powdered and extracted in concentrated hexane, acetone, ethanol, methanol and water. the extracts were tested for antimicrobial activity against escherichia coli (25922), bacillus subtilis (atcc 6051), enterococcus faecalis (51299) staphylococcus aureus (atcc 29213) and pseudomonas aeruginosa (atcc127853), using standard microbiological techniques. active crude extracts were macerated in concentrated methanol and tested for secondary metabolites including ...201627166532
isoquercitrin inhibits bladder cancer progression in vivo and in vitro by regulating the pi3k/akt and pkc signaling pathways.bladder cancer is the most common malignancy of the urinary system and is also one of the 10 most common cancers of the human body. currently, clinical treatment of bladder cancer mainly utilizes partial or total cystectomy, supplemented by conventional chemotherapy. however, such treatment has not fully improved the prognosis of patients and is associated with various side effects. studies have found that flavonoids extracted from plants can be used in radiotherapy and chemotherapy for the prev ...201627177091
performance of bemisia tabaci (genn.) biotype b (hemiptera: aleyrodidae) on weeds.bemisia tabaci (genn.) biotype b (hemiptera: aleyrodidae) is regarded as a pest with a large number of hosts, including crops and weeds. the performance of this whitefly on seven weeds was evaluated in order to identify the most suitable host. the following weeds that are very common in intense agricultural areas in the state of são paulo, brazil, were selected for this study: spurge (euphorbia heterophylla), beggarticks (bidens pilosa), red tasselflower (emilia sonchifolia), small-flower galins ...201427194066
prevalence of ectoparasites of indigenous chickens from dalahu region, kermanshah province, iran.ectoparasitism is an important factor associated with the poor production of indigenous chickens. the present study was undertaken to estimate the prevalence and ectoparasite diversity in indigenous chickens of the dalahu region in the western part of kermanshah province, iran.201627222329
herbal medicine use and linked suspected adverse drug reactions in a prospective cohort of ugandan inpatients.clinical history-taking can be employed as a standardized approach to elucidate the use of herbal medicines and their linked suspected adverse drug reactions (adrs) among hospitalized patients. we sought to identify herbal medicines nominated by ugandan inpatients; compare nomination rates by ward and gender; confirm the herbs' known pharmacological properties from published literature; and identify adrs linked to pre-admission use of herbal medicines.201627229463
the effect of the aqueous extract of bidens pilosa l. on androgen deficiency dry eye in rats.bidens pilosa l. (bp) is widely distributed in china and has been widely used as a traditional chinese medicine. the aim of this study was to examine the effect of the extract of bp on androgen deficiency dry eye and determine its possible mechanisms.201627337217
endogenous trans-zeatin content in plants with different metal-accumulating ability: a field survey.a field survey was conducted to evaluate soil metal pollution and endogenous trans-zeatin content in the leaves of plants growing at six sites in a metal-polluted area located in gejiu, yunnan, china. five plant species were collected, and the physicochemical properties and concentrations of five metals in the soil were analyzed. the trans-zeatin content in plant leaves was measured by high-performance liquid chromatography. based on the nemerow pollution index, the six sites were classified int ...201627613625
antioxidant activities of essential oil of bidens pilosa (linn. var. radita) used for the preservation of food qualities in north cameroon.this study aimed to determine the total antioxidant capacity of the essential oil (eo) of leaves of bidens pilosa (linn. var. radita) used as protectant of stored grains in northern cameroon. eo was characterized by gc-fid, antioxidant activity (aa) was determined by combining: evaluation of radical-scavenging activity, reducing power (rp) and co-oxidation of β-carotene methods. tests were carried out on crude and stored eo kept for two weeks at 31.48 ± 2.88°c and 58.56 ± 6.78% relative humidity ...201627625769
in vitro and in vivo anti-helicobacter activities of eryngium foetidum (apiaceae), bidens pilosa (asteraceae), and galinsoga ciliata (asteraceae) against helicobacter pylori.this study was performed to evaluate the antimicrobial activities of extracts of bidens pilosa, galinsoga ciliata, and eryngium foetidum against 6 clinical strains of helicobacter pylori in vitro and in vivo. broth microdilution method was used in vitro. in vivo, swiss mice were inoculated with h. pylori and divided into 5 groups; the control group received the vehicle and the four others received 125, 250, and 500 mg/kg of methanol extract of eryngium foetidum and ciprofloxacin (500 mg/kg) for ...201627631003
the fate of the herbicide propanil in plants of the littoral zone of the three gorges reservoir (tgr), china.the anti-seasonal hydrology with 30m water fluctuations in the three gorges reservoir (tgr) of china attracts growing environmental and ecological concerns. we investigated the biotransformation of the herbicide propanil in plants dominating in the littoral zone of the tgr by applying the (14)c-ring-labeled herbicide into non-aseptic hydroponic plant systems (cynodon dactylon, nelumbo nucifera and bidens pilosa), aseptic plants (lemna minor and lemna gibba) and cell suspension cultures (c. dacty ...201627745669
target and non-target site mechanisms developed by glyphosate-resistant hairy beggarticks (bidens pilosa l.) populations from mexico.in 2014 hairy beggarticks (bidens pilosa l.) has been identified as being glyphosate-resistant in citrus orchards from mexico. the target and non-target site mechanisms involved in the response to glyphosate of two resistant populations (r1 and r2) and one susceptible (s) were studied. experiments of dose-response, shikimic acid accumulation, uptake-translocation, enzyme activity and 5-enolpyruvyl shikimate-3-phosphate synthase (epsps) gene sequencing were carried out in each population. the r1 ...201627752259
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