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flow cytometry reveals that the rust fungus, uromyces bidentis (pucciniales), possesses the largest fungal genome reported--2489 mbp.among the eukaryotes, fungi have relatively small genomes (average of 44.2 mbp across 1850 species). the order pucciniales (basidiomycota) has the largest average genome size among fungi (305 mbp), and includes the two largest fungal genomes reported so far (puccinia chrysanthemi and gymnosporangium confusum, with 806.5 and 893.2 mbp, respectively). in this work, flow cytometry was employed to determine the genome size of the bidens pilosa rust pathogen, uromyces bidentis. the results obtained r ...201525784533
biochemical changes in terminal root galls caused by an ectoparasitic nematode, longidorus africanus: amino acids.the amino acids of terminal root galls caused by longidorus africanus on bur marigold (bidens tripartita l.) and grapevine (vitis vinifera l.) were studied. the galled roots of bur marigold contained 73% more cell-wall protein and 184% more free amino acids. the main changes among the free amino acids of the galled tissue were a large increase (1900%) in proline and a decrease in aspartic acid (56%) compared with the respective check tissue. hydroxyproline decreased in the wall protein fraction ...197119322388
biochemical changes in terminal root galls caused by an ectoparasitic nematode, longidorus africanus - nucleic acids.changes in dna and rna in roots of bur marigold fed upon by longidorus africanus were studied using analytical methods, radioactive precursors, and analytical csc1 density-gradient centrifugation. the analyses showed that almost twice as much rna and dna was present in parasitized root tips as in those of nonparasitized control plants. studies on the rates of incorporation of labeled thymidine and uridine confirmed the dna levels determined by analytical methods, but revealed a much higher incor ...197419319364
biochemical changes in terminal root galls caused by an ectoparasitic nematode, longidorus africanus: phenols, carbohydrates and cytokinins.biochemical changes occurred in roots of bur marigold and grapevine infected with longidorus africanus. phenols of infected root tips differed quantitatively from those of healthy root tips (optical density of 0.68 and 0.32, respectively). column chromatography of the phenol extracts resulted in more fractions in the infected than in the healthy root extract. of the enzymes involved in phenol metabolism, three were tested. no polyphenol oxidase activity was detected and no difference in catalase ...197219319273
medicinal plants used to treat tb in ghana.the current study was designed to document medicinal plant species that are traditionally used to treat tuberculosis (tb) by ghanaian communities.201526972879
endogenous trans-zeatin content in plants with different metal-accumulating ability: a field survey.a field survey was conducted to evaluate soil metal pollution and endogenous trans-zeatin content in the leaves of plants growing at six sites in a metal-polluted area located in gejiu, yunnan, china. five plant species were collected, and the physicochemical properties and concentrations of five metals in the soil were analyzed. the trans-zeatin content in plant leaves was measured by high-performance liquid chromatography. based on the nemerow pollution index, the six sites were classified int ...201627613625
novel platensimycin derivatives with herbicidal activity.faced with the need to develop herbicides with different modes of action on account of weed resistance to existing herbicides, the sesquiterpene lactones can be the starting point in the search for new bioactive compounds. lumisantonin and five novel amides have been evaluated against two monocotyledons and three dicotyledons.201625914183
the impact of herbal drug use on adverse drug reaction profiles of patients on antiretroviral therapy in zimbabwe.background. the main objective was to determine the impact of herbal drug use on adverse drug reactions in patients on antiretroviral therapy (art). methodology. patients receiving first-line art from the national roll-out program participated in this cross-sectional study. participants were interviewed and a data collection sheet was used to collect information from the corresponding medical record. results. the majority (98.2%) of participants were using at least one herbal drug together with ...201222506106
[decomposition of herbaceous species in reservoir riparian region of three gorges reservoir under flooding condition].a total of 10 annuals and perennials of herbaceous species were investigated in reservoir riparian region of three gorges reservoir. the correlations between the plants' nutrient release rate and the substrate composition and structural matter were studied under flooding condition. the decomposition rates of different species differed substantially, with the maximum of alternanthera philoxeroides (decomposition rate constant k = 0.0228 d(-1)) and the minimum of microstegium vimineum (k = 0.0029 ...201425509072
performance of bemisia tabaci (genn.) biotype b (hemiptera: aleyrodidae) on weeds.bemisia tabaci (genn.) biotype b (hemiptera: aleyrodidae) is regarded as a pest with a large number of hosts, including crops and weeds. the performance of this whitefly on seven weeds was evaluated in order to identify the most suitable host. the following weeds that are very common in intense agricultural areas in the state of são paulo, brazil, were selected for this study: spurge (euphorbia heterophylla), beggarticks (bidens pilosa), red tasselflower (emilia sonchifolia), small-flower galins ...201427194066
herbal medicine use and linked suspected adverse drug reactions in a prospective cohort of ugandan inpatients.clinical history-taking can be employed as a standardized approach to elucidate the use of herbal medicines and their linked suspected adverse drug reactions (adrs) among hospitalized patients. we sought to identify herbal medicines nominated by ugandan inpatients; compare nomination rates by ward and gender; confirm the herbs' known pharmacological properties from published literature; and identify adrs linked to pre-admission use of herbal medicines.201627229463
invasive congeners are unlikely to hybridize with native hawaiian bidens (asteraceae). 201323733530
low allozymic variation in the bidens pilosa l. complex (asteraceae).bidens alba, b. subalternans, and b. pilosa form a complex group based on their morphological similarities. bidens pilosa l. and b. subalternans dc. are herbs with a wide distribution in agricultural and disturbed areas. bidens alba (l.) dc. varies in size from herb to subshrub and has a coastal distribution. enzyme electrophoresis was used to evaluate genetic diversity in 12 populations of bidens. all but three loci (lap-1, est, and got) were monomorphic. est-1 and got were polymorphic only in ...200516187159
brain transcriptional profiles of male alternative reproductive tactics and females in bluegill sunfish.bluegill sunfish (lepomis macrochirus) are one of the classic systems for studying male alternative reproductive tactics (arts) in teleost fishes. in this species, there are two distinct life histories: parental and cuckolder, encompassing three reproductive tactics, parental, satellite, and sneaker. the parental life history is fixed, whereas individuals who enter the cuckolder life history transition from sneaker to satellite tactic as they grow. for this study, we used rnaseq to characterize ...201627907106
inhibiting mdsc differentiation from bone marrow with phytochemical polyacetylenes drastically impairs tumor metastasis.myeloid-derived suppressor cells (mdscs) are implicated in the promotion of tumor metastasis by protecting metastatic cancerous cells from immune surveillance and have thus been suggested as novel targets for cancer therapy. we demonstrate here that oral feeding with polyacetylenic glycosides (bp-e-f1) from the medicinal plant bidens pilosa effectively suppresses tumor metastasis and inhibits tumor-induced accumulation of granulocytic (g) mdscs, but does not result in body weight loss in a mouse ...201627857157
essential oils from ugandan medicinal plants: in vitro cytotoxicity and effects on il-1β-induced proinflammatory mediators by human gingival fibroblasts.the study investigated cytotoxicity of essential oils from four medicinal plants (bidens pilosa, ocimum gratissimum, cymbopogon nardus, and zanthoxylum chalybeum) on human gingival fibroblasts and their effects on proinflammatory mediators' secretion. cytotoxicity of essential oils was investigated using 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide assay. effects of essential oils at subcytotoxicity concentrations on interleukin- (il-) 6, il-8, and prostaglandin e2 (pge2) secre ...201627807462
the fate of the herbicide propanil in plants of the littoral zone of the three gorges reservoir (tgr), china.the anti-seasonal hydrology with 30m water fluctuations in the three gorges reservoir (tgr) of china attracts growing environmental and ecological concerns. we investigated the biotransformation of the herbicide propanil in plants dominating in the littoral zone of the tgr by applying the (14)c-ring-labeled herbicide into non-aseptic hydroponic plant systems (cynodon dactylon, nelumbo nucifera and bidens pilosa), aseptic plants (lemna minor and lemna gibba) and cell suspension cultures (c. dacty ...201627745669
antioxidant activities of essential oil of bidens pilosa (linn. var. radita) used for the preservation of food qualities in north cameroon.this study aimed to determine the total antioxidant capacity of the essential oil (eo) of leaves of bidens pilosa (linn. var. radita) used as protectant of stored grains in northern cameroon. eo was characterized by gc-fid, antioxidant activity (aa) was determined by combining: evaluation of radical-scavenging activity, reducing power (rp) and co-oxidation of β-carotene methods. tests were carried out on crude and stored eo kept for two weeks at 31.48 ± 2.88°c and 58.56 ± 6.78% relative humidity ...201627625769
the effect of the aqueous extract of bidens pilosa l. on androgen deficiency dry eye in rats.bidens pilosa l. (bp) is widely distributed in china and has been widely used as a traditional chinese medicine. the aim of this study was to examine the effect of the extract of bp on androgen deficiency dry eye and determine its possible mechanisms.201627337217
isoquercitrin inhibits bladder cancer progression in vivo and in vitro by regulating the pi3k/akt and pkc signaling pathways.bladder cancer is the most common malignancy of the urinary system and is also one of the 10 most common cancers of the human body. currently, clinical treatment of bladder cancer mainly utilizes partial or total cystectomy, supplemented by conventional chemotherapy. however, such treatment has not fully improved the prognosis of patients and is associated with various side effects. studies have found that flavonoids extracted from plants can be used in radiotherapy and chemotherapy for the prev ...201627177091
field trial of medicinal plant, bidens pilosa, against eimeriosis in broilers.eimeriosis is a severe protozoan disease in poultry. because of increasing concern about drug residue and drug resistance with the use of anticoccidial drugs, natural products are emerging as an alternative and complementary approach to control avian eimeriosis. our previous publication showed that feed supplemented with b. pilosa (bp) was effective at combating chicken eimeriosis in experimental settings. however, its efficacy against chicken eimeriosis under field conditions is not known. here ...201627098674
[protective effect of total flavones of bidens pilosa l. on iga1 induced injury of huvecs in henoch-schönlein purpura children patients].to explore the protective effect and mechanism of total flavones of bidens pilosa l. (tfb) on iga1 induced injury of venous endothelial cells in henoch-schönlein purpura (hsp) children patients. methods human umbilical venous endothelial cells (huvecs) were taken as subject. they were intervened by normal iga1 and hsp children patients' serum iga1, and added with different concentrations tfb at the same time. then they were divided into the blank control group, the normal control group, the hsp ...201627078994
bidens pilosa and its active compound inhibit adipogenesis and lipid accumulation via down-modulation of the c/ebp and pparγ pathways.obesity and its complications are a major global health problem. in this study, we investigated the anti-obesity effect and mechanism of an edible plant, bidens pilosa, and its active constituent. we first assessed the long-term effect of b. pilosa on body composition, body weight, blood parameters in icr mice. we observed that it significantly decreased fat content and increased protein content in icr mice. next, we verified the anti-obesity effect of b. pilosa in ob/ob mice. it effectively and ...201627063434
separation and identification of phenolic compounds in bidens pilosa l. by ultra high performance liquid chromatography with quadrupole time-of-flight mass spectrometry.a validated method based on ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry was established to separate and identify phenolic compounds in bidens pilosa l. mass spectrometry experiments were performed both in positive and negative ion modes. a total of 35 compounds were detected, and 26 phenolic compounds were unequivocally identified or tentatively assigned based on retention time, maximum uv absorption, molecular formula, and fragments. the ultr ...201627004754
auxin effects on pb phytoextraction from polluted soils by tegetes minuta l. and bidens pilosa l.: extractive power of their root exudates.the principal impediment for pb uptake by plants is the casparian strip in roots. it prevents metals reaching the xylem, thereby hampering translocation to the aerial organs. in the root apices, young root cells have thin cell walls and the casparian strip is not completely developed, which could facilitate pb uptake by roots at these vulnerable points. however, as the phytotoxic effects of pb reduce root growth and enhance suberization, entry of pb into the plant is avoided. we propose that the ...201626954477
photosynthetic electron-transfer reactions in the gametophyte of pteris multifida reveal the presence of allelopathic interference from the invasive plant species bidens pilosa.to date, the response of the fern gametophyte to its environment has received considerable attention. however, studies on the influence of plant invasion on the fern gametophyte are fewer. allelopathy has been hypothesized to play an important role in biological invasion. hence, it is necessary to study the allelopathy of invasive plant species to the fern gametophyte and elucidate the mechanisms by which invasive plants cause phytotoxicity. as one of the main invasive plants in china, bidens pi ...201626954232
herbicidal and cytotoxic constituents from aralia armata (wall.) seem.two new triterpenoids, 3β-hydroxyoleana-11,13(18)-diene-28,30-dioic acid (1) and 3-oxooleana-11,13(18)-diene-28,30-dioic acid (2), one novel triterpenoid glycoside, 3β-o-(6'-o-methyl-β-d-glucuronopyranosyl)oleana-11,13(18)-dien-28-oic acid (3) along with six known compounds (4 - 9) were isolated from the stem bark of aralia armata (wall.) seem. their structures were elucidated through extensive spectroscopic methods. the herbicidal activities of these compounds against bidens pilosa l., an invas ...201626948515
effects of co-cropping bidens pilosa (l.) and tagetes minuta (l.) on bioaccumulation of pb in lactuca sativa (l.) growing in polluted agricultural soils.polluted agricultural soils are a serious problem for food safety, with phytoremediation being the most favorable alternative from the environmental perspective. however, this methodology is generally time-consuming and requires the cessation of agriculture. therefore, the purpose of this study was to evaluate two potential phytoextractor plants (the native species bidens pilosa and tagetes minuta) co-cropped with lettuce growing on agricultural lead-polluted soils. the concentrations of pb, as ...201626940382
uptake and decomposition of the herbicide propanil in the plant bidens pilosa l. dominating in the yangtze three gorges reservoir (tgr), china.propanil (3',4'-dichloropropionanilide) is a selective post emergence herbicide for controlling broad leaf and grass weeds in rice (oryza sativa l.). after being taken up by plants, the fate of propanil in decomposing plant material is of particular importance to the phytoremediation of the environment. therefore, we investigated the biotransformation of propanil in the plant bidens pilosa under conditions close to those present in the three gorges reservoir (tgr), china. plants pre-treated with ...201626846318
beneficial effect of bidens pilosa on body weight gain, food conversion ratio, gut bacteria and coccidiosis in chickens.in the interests of food safety and public health, plants and their compounds are now re-emerging as an alternative approach to treat gastrointestinal diseases in chickens. here, we studied the impact of the edible medicinal plant, b. pilosa, on growth performance, gut bacteria and coccidiosis in chickens. first, we found that b. pilosa significantly elevated body weight gain and lowered feed conversion ratio in chickens. next, we showed that b. pilosa reduced cecal damage as evidenced by increa ...201626765226
evaluation of two brazilian indigenous plants for phytostabilization and phytoremediation of copper-contaminated soils.indigenous plants have been grown naturally and vigorously in copper contaminated soils. thus, the aim of this study was to evaluate the phytoremediation ability of two indigenous plants naturally grown in two vineyard soils copper contaminated, and in a copper mining waste. however, it was evaluated the macro and micronutrient uptake and the potential of phytoremediation. so, a greenhouse study was carried out with bidens pilosa and plantago lanceolata in samples of vineyard soils (inceptisol a ...201526675903
evaluation of two brazilian indigenous plants for phytostabilization and phytoremediation of copper-contaminated soils.abstractindigenous plants have been grown naturally and vigorously in copper contaminated soils. thus, the aim of this study was to evaluate the phytoremediation ability of two indigenous plants naturally grown in two vineyard soils copper contaminated, and in a copper mining waste. however, it was evaluated the macro and micronutrient uptake and the potential of phytoremediation. so, a greenhouse study was carried out with bidens pilosa and plantago lanceolata in samples of vineyard soils (ince ...201526560649
mechanistic study of the phytocompound, 2- β -d-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne in human t-cell acute lymphocytic leukemia cells by using combined differential proteomics and bioinformatics approaches.bidens pilosa, a medicinal herb worldwide, is rich in bioactive polyynes. in this study, by using high resolution 2-dimensional gel electrophoresis coupled with mass spectrometry analysis, as many as 2000 protein spots could be detected and those whose expression was specifically up- or downregulated in jurkat t cells responsive to the treatment with 2-β-d-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne (ghtt) can be identified. ghtt treatment can upregulate thirteen proteins involved in si ...201526557148
changes in gametophyte physiology of pteris multifida induced by the leaf leachate treatment of the invasive bidens pilosa.in recent years, the response of fern gametophytes to environment has raised much attention. however, studies on the influence of plant invasion to fern gametophytes are scarce. allelopathy plays an important role in biological invasion. hence, it is necessary to study the allelopathic effects of invasive plants on fern gametophytes and elucidate the mechanisms by which invasive plants cause phytotoxicity. as one of the main invasive plants in china, bidens pilosa exhibits allelopathic effects o ...201626490937
assessment of the root system of brassica juncea (l.) czern. and bidens pilosa l. exposed to lead polluted soils using rhizobox systems.the purpose of this study was to compare the behavior of the root system of one of the most frequently cited species in phytoremediation indian mustard [brassica juncea (l.) czern.] and a representative perennial herb (bidens pilosa l.) native of argentina, for different concentrations of lead in soils through chemical and visualization techniques of the rhizosphere. lead polluted soils from the vicinity of a lead recycling plant in the locality of bouwer, were used in juxtaposed rhizobox system ...201626292209
antiageing mechanisms of a standardized supercritical co 2 preparation of black jack (bidens pilosa l.) in human fibroblasts and skin fragments.the use of topical retinoids to treat skin disorders and ageing can induce local reactions, while oral retinoids are potent teratogens and produce several unwanted effects. this way, efforts to explore complementary care resources should be supported. based on this, we evaluate the antiageing effects of a supercritical co2 extract from bidens pilosa l. (bpe-co2a) containing a standardized multicomponent mixture of phytol, linolenic, palmitic, linoleic, and oleic acids. bpe-co2a was assessed for ...201525883669
bidens pilosa formulation improves blood homeostasis and β -cell function in men: a pilot study.b. pilosa has long been purported to have antidiabetes activity, but despite the advancement in phytochemistry and animal models of diabetes, no human clinical trials have been conducted to date. here, we evaluated the effect of a b. pilosa formulation on fasting blood glucose (fbg), fasting serum insulin, and glycosylated hemoglobin a1c (hba1c) in diabetic subjects. the b. pilosa formulation reduced the level of fbg and hba1c in diabetics but increased fasting serum insulin in healthy subjects. ...201525866541
effects of a native parasitic plant on an exotic invader decrease with increasing host age.understanding changes in the interactions between parasitic plants and their hosts in relation to ontogenetic changes in the hosts is crucial for successful use of parasitic plants as biological controls. we investigated growth, photosynthesis and chemical defences in different-aged bidens pilosa plants in response to infection by cuscuta australis. we were particularly interested in whether plant responses to parasite infection change with changes in the host plant age. compared with the non-in ...201525838325
isoquercitrin inhibits the progression of pancreatic cancer in vivo and in vitro by regulating opioid receptors and the mitogen-activated protein kinase signalling pathway.pancreatic cancer is a common malignant tumour that affects individuals worldwide. in recent years, the incidence and mortality rates of pancreatic cancer have continuously increased. currently, the primary clinical treatment methods for pancreatic cancer include surgical resection, chemotherapy and radiotherapy. however, these treatment methods rarely produce satisfactory therapeutic outcomes. extensive research has also proven that the effective components of several traditional chinese medici ...201525434366
tetraoxanes as a new class of efficient herbicides comparable with commercial products.several 1,2,4,5-tetraoxanes were synthesised, and their herbicidal activity was tested against weeds and compared with the activity of commercial herbicides glyphosate and imazethapyr.201525157959
n-butanol fraction of entada phaseoloides ethanol extract inhibits hepatocellular carcinoma hepg2 cell proliferation by inducing apoptosis.to screen for substances with inhibitory effects on the proliferation of hepatocellular carcinoma (hcc) hepg2 cell line from extracts of traditional chinese medicinal plants including heliciopsis lobata (merr.) sleum, bidens pilosa, entada phaseoloides, plantago major, and smilax, and unveil their mechanism of action.201424965399
a trade off between separation, detection and sustainability in liquid chromatographic fingerprinting.it is now recognized that analytical chemistry must also be a target for green principles, in particular chromatographic methods which typically use relatively large volumes of hazardous organic solvents. more generally, high performance liquid chromatography (hplc) is employed routinely for quality control of complex mixtures in various industries. acetonitrile and methanol are the most commonly used organic solvents in hplc, but they generate an impact on the environment and can have a negativ ...201424952659
[interspecific association of companion species in artemisia annua community in southwest of china].the interspecific association of companion species in artemisia annua community in 48 region of southwest china was analyzed by variance analysis, chi2-test and association indices. the total related variance ratio among species in a. annua community was 2.05. among 45 species pairs of 10 main species in the community, only 4 pairs showed significant negative correlations. chi2 test, pc, oi, di and ac values indicated pairs 1-8 (a. annua- a. lactiflora), 1-9 (a. annua- setaria viridis) and 1-10 ...201323724672
phytotoxicity of volatile oil from eucalyptus citriodora against some weedy species.a study was undertaken to explore the phytotoxicity of volatile essential oil from eucalyptus citriodora hook. against some weeds viz. bidens pilosa, amaranthus viridis, rumex nepalensis, and leucaena leucocephala in order to assess its herbicidal activity. dose-response studies conducted under laboratory conditions revealed that eucalypt oils (in concentration ranging from 0.0012 to 0.06%) greatly suppress the germination and seedling height of test weeds. at 0.06% eucalypt oil concentration, n ...200717717987
prevalence of ectoparasites of indigenous chickens from dalahu region, kermanshah province, iran.ectoparasitism is an important factor associated with the poor production of indigenous chickens. the present study was undertaken to estimate the prevalence and ectoparasite diversity in indigenous chickens of the dalahu region in the western part of kermanshah province, iran.201627222329
medicinal plants used in malaria treatment by prometra herbalists in uganda.the aim of the survey was to document medicinal plants used in malaria treatment by prometra (promocion de la medicina tradicional amazonica) traditional medical practitioners (tmps) of uganda and for search of new antiplasmodial herbal medicines (hms) for further phytochemical analysis.201424928824
botanical, pharmacological, phytochemical, and toxicological aspects of the antidiabetic plant bidens pilosa l.bidens pilosa l. is an easy-to-grow, widespread, and palatable perennial on earth. hence, it has traditionally been used as foods and medicines without noticeable adverse effects. despite significant advancement in chemical and biological studies of b. pilosa over the past few years, comprehensive and critical reviews on its anti-diabetic properties are missing. the present review is to summarize up-to-date information on the pharmacology, phytochemistry, and toxicology of b. pilosa, in regard t ...201424616740
the role of pentacyclic triterpenoids in the allelopathic effects of alstonia scholaris.alstonia scholaris is a tropical evergreen tree native to south and southeast asia. alstonia forests frequently lack understory species. however, potential mechanisms-particularly the allelochemicals involved-remain unclear. in the present study, we identified allelochemicals of a. scholaris, and clarified the role of allelopathic substances from a. scholaris in interactions with neighboring plants. we showed that the leaves, litter, and soil from a. scholaris inhibited growth of bidens pilosa-a ...201424390624
analgesic and antiinflammatory activities of the ethyl acetate fraction of bidens pilosa (asteraceae).bidens pilosa is an asteraceae widely used in traditional medicine for the treatment of various ailments including pain and inflammation. the present work was undertaken to assess the analgesic and antiinflammatory properties of the ethyl acetate fraction of methylene chloride/methanol (1:1) extract of leaves of bidens pilosa at the gradual doses of 50, 100 and 200 mg/kg in mice and rats, respectively. the analgesic properties of bidens pilosa were investigated using the acetic acid writhing, ho ...201424242914
preliminary phytochemical screening and molluscicidal activity of the aqueous extract of bidens pilosa linné (asteraceae) in subulina octona (mollusca, subulinidade).the aim of this study was to establish reference concentrations (lc₅₀ e lc₉₀) of aqueous extracts of bidens pilosa on the land snail subulina octona, in order to assess the changes caused by 24 and 48 h exposure to the sublethal concentration regarding species' fecundity, hatchability and in offspring produced after exposure to confirm the presence of tannins, saponins and flavonoids in this plant species. eggs newly hatched and 30 day-old snails were exposed to sublethal concentration, calculat ...201324141417
[chemical constituents in whole herb of bidens pilosa var. radiata].to study the chemical constituents of bidens pilosa var. radiata.201324010324
decrease of reactive oxygen species and reciprocal increase of nitric oxide in human dermal endothelial cells by bidens pilosa extract: a possible explanation of its beneficial effect on livedo vasculopathy. 201323819986
effect of floral sources on the antioxidant, antimicrobial, and anti-inflammatory activities of honeys in taiwan.we evaluated the antioxidant, antibacterial, and anti-inflammatory activities of honey made from different floral sources, including the medicinal herb bidens pilosa, fruit trees, dimocarpus longan, litchi chinensis, and citrus maxima, the taiwanese endemic plant aglaia formosana, and a multifloral forest. the total phenolic and flavonoid contents of the honey made from b. pilosa were significantly higher than those of the other honeys. the honey from b. pilosa also had significantly greater sca ...201323561193
wild leafy vegetables consumed in buhera district of zimbabwe and their phenolic compounds content.a questionnaire was used to gather information on the wild leafy vegetables consumed. the phenolic concentrations were determined by the vanillin, butanol, and tannin binding assays. seventy-nine traditional vegetables were mentioned by the respondents and 20 of these were classified according to their species. the contents of flavonoids varied from 1.2 mg/g for cleome gynandra to 8.0 mg/g for bidens pilosa. the levels of proanthocyanidins ranged from 1.9 mg/g for lettuce to 11.2 mg/g for bidens ...201323445395
extraction of antioxidant components from bidens pilosa flowers and their uptake by human intestinal caco-2 cells.bidens pilosa l. var. radiata (bpr, asteraceae) is a commonly used folk medicine for treating various disorders such as diabetes, inflammation and hypertension. recent studies to determine its chemical composition have revealed three di-o-caffeoylquinic acids (dicqas) and three polyacetylene glucosides (pgas) to be among the major bioactive markers. to obtain the major compounds of these two chemical classes, the ethyl acetate fraction (em) obtained using liquid-liquid partition from the methano ...201323353127
what's eating you? the sticktight flea (echidnophaga gallinacea). 201222611740
effect on blood pressure of a dietary supplement containing traditional medicinal plants of côte d'ivoire.a medicinal composition containing salt (sodium chloride) is given as a traditional dietary supplement to hypertensive patients (tdshp) in côte d'ivoire. it consists of whole plant of bidens pilosa (asteraceae) and fresh leaves of moringa oleifera (moringaceae).201222480886
investigation of the extracts from bidens pilosa linn. var. radiata sch. bip. for antioxidant activities and cytotoxicity against human tumor cells.the aim of this study was to evaluate antioxidant activities and cytotoxicity against human tumor cell lines of extracts from bidens pilosa linn. var. radiata sch. bip. (bp). total phenolic and flavonoid contents of the extracts were determined by ultraviolet spectrophotometry. furthermore, the antioxidant properties of different polarity fractions extracted from bp were evaluated using dpph and abts radical scavenging test and frap assay. the ethyl acetate fraction (ee-bp) showed the highest an ...201322382861
plants used as antidiabetics in popular medicine in rio grande do sul, southern brazil.plants are widely as antidiabetics. the study of these plants is essential because many of them may have undesirable effects, such as acute or chronic toxicity; or their use may even delay or discourage the adoption of the proper and effective treatment.201222079795
characterization and risk assessment of polychlorinated biphenyls in soils and vegetations near an electronic waste recycling site, south china.this study aimed at identifying the levels of pcbs generated from e-waste recycling, and their potential impacts on the soils and vegetations as well. the σpcbs concentrations in soil and plant samples ranged from 7.4 to 4000 ng g(-1) and from 6.7 to 1500 ng g(-1), respectively. for the plant samples, chrysanthemum coronarium l. from vegetable field and the wild plant bidens pilosa l. from the burning site showed relatively higher pcb concentrations than other species. for the soil samples, the ...201121813154
the first total synthesis of cytopiloyne, an anti-diabetic, polyacetylenic glucoside.the first total synthesis of cytopiloyne 1, a novel bioactive polyacetylenic glucoside isolated from the extract of bidens pilosa, is described. the structure of cytopiloyne was determined to be 2-β-d-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetrayne by using various spectroscopic methods, but the chirality of the polyyne moiety was unknown. herein, the convergent synthesis of two diastereomers of cytopiloyne by starting from commercially available 4-(2-hydroxyethyl)-2,2-dimethyl-1,3-diozolan ...201121681841
comparison of the nutritive value and biological activities of the acetone, methanol and water extracts of the leaves of bidens pilosa and chenopodium album.a resurgence of interest has developed in wild vegetables for their possible medicinal values in diets. wild plant species provide minerals, fibre, vitamins and essential fatty acids and enhance taste and color in diets. for this reason, the nutritional, phytochemical, antioxidant and antibacterial activities of the acetone, methanol and water extracts of the leaves of bidens pilosa and chenopodium album were investigated. the proximate analysis showed that the leaves of the plants contained app ...201321485705
compilation of secondary metabolites from bidens pilosa l.bidens pilosa l. is a cosmopolitan annual herb, known for its traditional use in treating various diseases and thus much studied for the biological activity of its extracts, fractions and isolated compounds. polyacetylenes and flavonoids, typical metabolite classes in the bidens genus, predominate in the phytochemistry of b. pilosa. these classes of compounds have great taxonomic significance. in the asteraceae family, the acetylene moiety is widely distributed in the heliantheae tribe and some ...201121270729
hplc method development and validation of cytotoxic agent phenyl-heptatriyne in bidens pilosa with ultrasonic-assisted cloud point extraction and preconcentration.extraction and pre-concentration of a bioactive marker compound, phenyl-1,3,5-heptatriyne from bidens pilosa, prior to hplc has been demonstrated using both organic and ecofriendly solvents. non-ionic surfactants, viz. triton x-100, triton x-114 and genapol x-80, were used for extraction. no back-extraction or liquid chromatographic steps were required to remove the target phytochemical from the surfactant-rich extractant phase. the optimized cloud point extraction procedure has been shown to be ...201120812202
effects of bidens pilosa l. var. radiata scherff on experimental gastric lesion.bidens pilosa l. var. radiata scherff: (bp) is a plant used as a traditional folk medicine. bp, cultivated with only green manure on miyako island, okinawa prefecture, was processed to powder and is referred to as mmbp. we have reported that mmbp has antioxidant, anti-inflammatory, and anti-allergy properties. in this study, we investigated the effects of mmbp on several experimental gastric lesions induced by hcl/etoh, a non-steroidal anti-inflammatory drug, or cold-restraint stress, comparing ...201020526746
polyacetylenes and flavonoids from the aerial parts of bidens pilosa.bidens pilosa is used in various folk medicines such as antimalarial, antibacterial, blood pressure-lowering, and antihyperglycemic agents. phytochemical investigation of the aerial parts of this plant yielded 10 polyacetylenes and 9 flavonoids, including four new polyacetylenes (5, 7- 9) and one new chalcone glucoside (11). the molecular structures of the isolated compounds were elucidated by comprehensive spectroscopic analysis.201020108176
[characteristics of cadmium tolerance and bioaccumulation of bidens pilosa l. seedlings].bidens pilosa l. has been identified as a newly found cd-hyperaccumulator. in the present study, the characteristics of its cd tolerance (growth response and physiological and biochemical characteristics) and accumulation were examined. the results showed that low cd treatments (< or =32 mg/kg) could enhance plant growth, the dry biomass of shoot and root increased by 32.4%-44.7% and 29.1%-57.6%, respectively, at cd concentrations 8-32 mg/kg when compared with the control. the shoot dry biomass ...200919968126
[observation on therapeutic effect of runmushu oral liquid in treating xerophthalmia in postmenopausal women].to objectively evaluate the therapeutic effect and safety of runmushu oral liquid (rms) for the treatment of xerophthalmia in postmenopausal women.200919852302
season variations for metallic elements compositions study in plant bidens pilosa l. var. radiate sch. in central taiwan.the possibility of using bidens pilosa l. var. radiate sch leaves as environmental indicators of metallic element pollution has been investigated. samples were analyzed with respect to the following pollutants: zn, mn, cu, ni, pb, cd, cr, fe, ca, and mg by using inductively coupled plasma atomic emission spectrometry. the results obtained on the metallic elements had the following average composition order: ca > mg > fe, mn > zn > cu > ni > pb > cr > cd for plant b. pilosa l. var. radiate sch. a ...201019685152
differential growth response to arbuscular mycorrhizal fungi and plant density in two wild plants belonging to contrasting functional types.the effect of arbuscular mycorrhizal fungi (amf) on plant growth was examined in two wild plant species belonging to contrasting functional types: an annual forb (bidens pilosa, asteraceae) and a deciduous shrub (acacia caven, fabaceae) at three contrasting plant densities (one, two, and three individuals per pot). amf had a slightly negative effect on b. pilosa when the species grew in isolation while they positively affected a. caven. positive effects of amf on shoot mass of a. caven decreased ...200919444488
screen of chinese weed species for cadmium tolerance and accumulation characteristics.the cadmium (cd) tolerance and metal-accumulation characteristics of 29 species (18 families) of weed were studied by using outdoor pot-culture experiments. the results of this screening showed that bidens pilosa and kalimeris integrifolia (both asteraceae) expressed some properties that are characteristic of cd hyperaccumulators. in 10 mg/kg cd-spiked soil, they accumulated a good deal of cd in shoots (28 and 25 mg/kg dw, respectively) with high cd enrichment factors (efs; concentration in plan ...201319260234
[hyperaccumulative characteristics of 7 widely distributing weed species in composite family especially bidens pilosa to heavy metals].hyperaccumulator is the main point of phytoremediating contaminated soils by heavy metals, and the identification of hyperaccumulator is still the difficult and key step of phytoremediation. the outdoor pot-culture experiment was used to study the hyperaccumulative characteristics of 7 widely distributing weed species in northeast of china to heavy metals. the results in screening experiment showed that taraxacum mongolicum and bidens pilosa indicated strong tolerance to cd single and cd-pb-cu-z ...200819143394
bidens identification using the noncoding regions of chloroplast genome and nuclear ribosomal dna.bidens pilosa l. is a plant producing barbed fruits which, due to its method of seed dispersal, is commonly found during forensic investigations. in taiwan there are three varieties of the species, radiata, minor and pilosa. fragments of these three varieties are difficult to differentiate by traditional morphological characteristics and until now little is known of their genetic composition. to discover genetic polymorphisms among these varieties, five loci within the nuclear and chloroplast ge ...200819083787
joint effects of arsenic and cadmium on plant growth and metal bioaccumulation: a potential cd-hyperaccumulator and as-excluder bidens pilosa l.joint effects of arsenic (as) and cadmium (cd) on the growth of bidens pilosa l. and its uptake and accumulation of as and cd were investigated using the field pot-culture experiment. the results showed that single cd (<or=25 mg kg(-1)) and as (<or=50 mg kg(-1)) treatments could promote the growth of b. pilosa, resulting in 34.5-104.4% and 21.0-43.0%, respectively, increase in the dry biomass of shoots while compared with that under the control conditions. however, under the co-contamination of ...200919070954
antioxidant activity of extracts and flavonoids from bidens tripartita.extracts from herb and flowers of bidens tripartita l. (asteraceae), obtained using solvents of different polarity, were studied for their radical scavenging effects. antioxidant activities of pure flavonoids: flavanomarein (isookanin 7-o-glucoside), cynaroside (luteolin 7-o-glucoside) and luteolin, which had been isolated from this plant, were also evaluated. radical-scavenging activity was measured by electron paramagnetic resonance (epr) spectroscopy using stable 1,1-diphenyl-2-picrylhydrazyl ...201618540165
cadmium tolerance and accumulation characteristics of bidens pilosa l. as a potential cd-hyperaccumulator.recently, researchers are becoming interested in using hyperaccumulators for decontamination of heavy metal polluted soils, whereas few species that hyperaccumulate cadmium (cd) has been identified in the plant kingdom. in this study, the physiological mechanisms at the seedling stage and growth responses and cd uptake and accumulation at flowering and mature stages of bidens pilosa l. under cd treatments were investigated. at the seedling stage, when soil cd was lower than 16mgkg(-1), the plant ...200918513866
rwandan female genital modification: elongation of the labia minora and the use of local botanical species.the elongation of the labia minora is classified as a type iv female genital mutilation by the world health organization. however, the term mutilation carries with it powerful negative connotations. in rwanda, the elongation of the labia minora and the use of botanicals to do so is meant to increase male and female pleasure. women regard these practices as a positive force in their lives. this paper aims to assess whether rwandan vaginal practices should indeed be considered a form of female gen ...200818247211
allelopathy on bark of downed logs of chamaecyparis obtusa sieb. and zucc. var. formosana (hayata) rehder.chamaecyparis obtusa sieb. and zucc. var. formosana (hayata) rehder is the dominant species in the temperate forest of yuanyang lake nature reserve (yyl), taiwan. although downed logs of c. obstusa var. formosana occupy only a small percentage of the forest floor area in yyl, they are important regeneration substrates. seedlings of this species often grow without competition on the new downed logs, and a few broadleaf trees grow with them. we hypothesized that the bark of the newly fallen logs p ...200717476467
flavonoids, centaurein and centaureidin, from bidens pilosa, stimulate ifn-gamma expression.bidens pilosa is used as an ethnical medicine for bacterial infection or immune modulation in asia, america and africa. here, we employed an ifn-gamma promoter-driven luciferase reporter construct and t cells to characterize immunomodulatory compounds from this plant based on a bioactivity-guided isolation principle. we found that pha, a positive control, caused a six-fold increase in ifn-gamma promoter activity. in contrast, hot water crude extracts from bidens pilosa and its butanol subfractio ...200717408892
[toxicity of pesticides used in chrysanthemum crops to eggs and nymphs of orius insidiosus (say) (hemiptera: anthocoridae)].the objective of this study was to evaluate the toxicity of some pesticides used in chrysanthemum crops to eggs and nymphs of orius insidiosus (say). the bioassays were carried out at 25 +/- 2 degrees c, 70 +/- 10% rh and 12h photophase. for the tests with eggs, stems of bidens pilosa l. previously exposed to predator oviposition were dipped for five seconds in aqueous dilution of the pesticides, using 40 eggs per treatment. the pesticides were applied on nymphs using a potter's tower. forty fir ...200717352073
influence of photoperiod on orius thyestes herring (hemiptera: anthocoridae) reproduction and longevity.several species of orius wolff are used in biological control of thrips in protected cultivations in temperate regions, but some of them show reproductive diapause, compromising the efficiency of these agents of biological control. there are no reports on the biology of the neotropical species orius thyestes herring under different environmental conditions. the purpose of this work was to investigate the influence of photoperiod on reproduction and longevity of this predator. nymphs were kept in ...200617061797
differential effects of 11-ketotestosterone on dimorphic traits in a teleost with alternative male reproductive morphs.species with dimorphic males typically have one morph (type i) associated with territoriality and courtship, and another morph (type ii) associated with cuckoldry. in teleost fishes, type i males generally have higher levels of the androgen 11-ketotestosterone (kt) than type ii males. is kt causal to phenotypic differences between morphs? we investigated this question in the midshipman fish (porichthys notatus) in which type i males have detectable levels of kt during the breeding season, wherea ...200515811353
polyacetylenic compounds and butanol fraction from bidens pilosa can modulate the differentiation of helper t cells and prevent autoimmune diabetes in non-obese diabetic mice.compelling evidence suggests that infiltrating cd4+ type i helper t (th1) cells in the pancreatic islets play a pivotal role in the progression of diabetes in non-obese diabetic (nod) mice. we demonstrate in the present report that a butanol fraction of b. pilosa suppressed the development of diabetes, helped maintain levels of blood sugar and insulin in nod mice in a dose-dependent manner and elevated the serum ige levels regulated by th2 cytokines in nod mice. moreover, the butanol fraction in ...200415549660
[assessment of antioxidant activity of natural compound by water- and lipid-soluble antioxidant factor].we evaluated the antioxidant activity of natural compounds in water-soluble and lipid-soluble phases and found that ferulic acid, quercetin and caffeic acid showed stronger activity in the water-soluble phase. various fractions isolated from bidens pilosa showed this activity mainly in the water-soluble phase. antioxidant activity in the lipid-soluble phase of propolis depended on the lipophilic extraction.200415516812
metabolite profiling and chemopreventive bioactivity of plant extracts from bidens pilosa.bidens pilosa has been used as a folk medicine in various medications and as a popular ingredient in herb teas. chemopreventive activities of crude and fractionated plant extracts of bidens pilosa were evaluated in this study. ethyl acetate and butanolic fractions, partitioned from the total crude extract of bidens pilosa, exhibited significant scavenging free radical activity (ic(50) values approximately = with 14-17 microg/ml) comparable to that of alpha-tocopherol. strong effects on the inhib ...200415507368
a logical (discrete) formulation for the storage and recall of environmental signals in plants.when subjected to an appropriate asymmetric stimulus, seedlings of bidens pilosa l. "store" a symmetry-breaking instruction that will finally take effect (in the form of a differential growth of the cotyledonary buds) only if the plants are in a state in which they can "recall" this information. the ability of the plants to recall the stored symmetry-breaking instruction may be switched "on" or "off" by the application of a variety of stimuli. although its detailed phenomenology is rather compli ...200415375730
in vitro study of the antioxidant and immunomodulatory activity of aqueous infusion of bidens pilosa.bidens pilosa is an annual plant from tropical america with anti-inflammatory properties in hepatitis, laryngitis, headache and digestive disorders, among others. its wide pharmacological applications can be attributed to its chemical composition, with inhibitory effects on pathogenic microorganisms and flavonoids, which show strong antioxidant capacities. we investigated the antioxidant activity of an aqueous infusion of bidens pilosa by studying its protective effect on the hemolysis induced b ...200415234771
allelopathic potential of macaranga tanarius (l.) muell.-arg.macaranga tanarius is widely distributed in the abandoned lowlands of taiwan where substantial amounts of leaves accumulate on the ground. a unique pattern of weed exclusion underneath trees is often found and thought to result from allelopathic interactions. density-dependent phytotoxicity analysis of lactuca sativa l. (lettuce) growing in soil mixed with the powder of m. tanarius leaves showed a significant deviation from the expected yield-density relationship. lettuce growth was most suppres ...200312857035
a new disubstituted acetylacetone from the leaves of bidens pilosa linn.phytochemical investigation of the leaves of bidens pilosa lead to the isolation and characterization of a new disubstituted acetylacetone (1) named as 3-propyl-3-(2,4,5-trimethoxy)benzyloxy-pentan-2,4-dione.200312674146
antileukemic activity of bidens pilosa l. var. minor (blume) sherff and houttuynia cordata thunb.to evaluate the anti-leukemic activity of bidens pilosa l. var. minor (blume) sherff and houttuynia cordata thunb., cytotoxicity tests with an xtt-based colorimetric assay were used. five leukemic cell lines, namely l1210, u937, k562, raji and p3hr1, were cultured with hot water extracts of b. pilosa var. minor or h. cordata. hot water extracts of b. pilosa var. minor inhibited these five leukemic cells with ic50s between 145 microg/ml and 586 microg/ml. the effect was greatest on four cell line ...200111527072
5-o-methylhoslundin: an unusual flavonoid from bidens pilosa (asteraceae). 200010793259
a mathematical model for storage and recall functions in plants.in plantlets of bidens pilosa l., under severely limiting environmental conditions the growth of the buds at the axil of the cotyledons (cotyledonary buds) is asymmetric (i.e. one of the buds starts growing before the other one), this asymmetry being oriented by the pricking of one of the cotyledons (i.e. pricking one cotyledon increases the probability that the bud at the axil of the other cotyledon be the first to start to grow). as long as the plant apex (i.e. the terminal bud) is present, th ...200010742914
antihyperglycemic acetylenic glucosides from bidens pilosa.in vivo bioassay-guided fractionation of the aqueous alcohol extract of the aerial parts of bidens pilosa sch. bip. var. radiata (asteraceae) using c57 bl/ks-db/db mice as a model for type 2 diabetes, yielded two known polyacetylenic glucosides, identified as 2-beta-d-glucopyranosyloxy-1-hydroxy-5(e)-tridecene-7,9,11-+ ++triyne (1) and 3-beta-d-glucopyranosyloxy-1-hydroxy-6(e)-tetradecene-8,10,1 2-triyne (2). a 3:2 mixture of compounds 1 and 2 effected a significant drop in blood glucose.200010705745
synthesis and herbicidal activity of 2alpha, 4alpha-dimethyl-8-oxabicyclo[3.2.1]oct-6-en-3-one derivatives.the catalytic oxidation of 2alpha,4alpha-dimethyl-8-oxabicyclo[3.2. 1]oct-6-en-3-one with osmium tetraoxide and excess hydrogen peroxide resulted in the formation of 2alpha,4alpha-dimethyl-6, 7-exo-isopropylidenedioxy-8-oxabicyclo[3.2.1]octan-3-one (2), with 91% yield. addition of aryllithium reagents to this compound resulted in the formation of the aromatic alcohols (6a-h) with 48-76% yield. these alcohols were treated with thionyl chloride in pyridine, and the corresponding alkenes (7a-h) wer ...199910552894
activities of the pharmaceutical technology institute of the oswaldo cruz foundation with medicinal, insecticidal and insect repellent plants.in addition to original research, far-manguinhos, the pharmaceutical division of the brazilian ministry of health's oswaldo cruz foundation (fiocruz), devotes major attention to the finalising of products for use in public health campaigns or, under contract, for private industrial development. emphasis is on standardisation, adequate supply, safety in use and efficacy. among the products discussed in this summary of some of its activities in the chemical and pharmaceutical fields are medicinal ...199910412493
[drug or plant substances which antagonize venoms or potentiate antivenins].dendroaspis jamesoni (elapidae) and echis oceliatus (viperidae) are responsible for most of severe evenomation in cameroon. toxicity of venoms of these two species has been measured using mice according to the method of spearman & kàrber. the effect on experimental envenomation of various drugs (atropine, promethazine, neostigmine, hydrocortisone, pentosane sulfuric polyester, heparin, tranexamic acid and aminocaproic acid) and plant extracts (schumanniophyton magnificum, bidens pilosa, securida ...19979479470
is membrane potential involved in calmodulin gene expression after external stimulation in plants?in bidens pilosa (cv. radiata), a non-injurious stimulus induces a local and transient change in membrane potential, and an injurious stimulus induces a transmitted electrical signal described as the combination of an action potential and a slow wave. we have studied calmodulin gene expression after these stimuli. when the stimulus is non-injurious, calmodulin mrna accumulation is only increased in the stimulated region. in contrast, when the stimulus is injurious, mrna accumulation takes place ...19968603755
control of a symmetry-breaking process in the course of the morphogenesis of plantlets of bidens pilosa l.a mechanism involving transport, storage and retrieval of a symmetry-breaking message controls the relative growth rate of the cotyledonary buds of plantlets of bidens pilosa l. the asymmetry was induced by administering a few needle pricks to one cotyledon of each plant. the storage of the symmetry-breaking message was independent of the number of pricks ("all or nothing" process) and irreversible. however, various treatments could render the plants either able to retrieve the stored symmetry-b ...199124194158
constituents of bidens pilosa l.: do the components found so far explain the use of this plant in traditional medicine?the dried aerial parts of bidens pilosa l. were extracted with petrol ether, chloroform, methanol, and methanol/water. the petrol ether and the methanol/water extracts showed some antimicrobial activity. fractionation of the extracts yielded well known substances, most of which have, however, not yet been described as constituents of bidens pilosa. several of these substances have previously been shown to be biologically active. thus, phenylheptatriyne, linolic acid and linolenic acid have antim ...19911674399
[the role of mineral ions in controlling morphogenesis in plants: a case of the inhibition of growth of the hypocotyle of bidens pilosa l].mineral ions are implicated in various events occurring in the transduction of messages in plants, from the reception of the initial signal to the final morphogenetic expression. ions may be involved also in the possible migration, storage and retrieval of the message. in a number of cases, cellular exchange of ca2+ have been shown to occur at the reception of a signal. this is the reason why ca2+ has often been considered as a "second messenger". for the possible message migration, cellular exc ...19892534954
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