Publications

optimization of antifungal extracts from ficus hirta fruits using response surface methodology and antifungal activity tests.	the fruits of ficus hirta (fh) display strong antifungal activity against penicillium italicum and penicillium digitatum. in order to optimize the extraction conditions of antifungal extracts from fh fruit, various extraction parameters, such as ethanol concentration, extraction time, solvent to solid ratio and temperature, were chosen to identify their effects on the diameters of inhibition zones (dizs) against these two penicillium molds. response surface methodology (rsm) was applied to obtai ...	2015	26528961
in vitro and in vivo activity of essential oils against major postharvest pathogens of kinnow (citrus nobilis × c. deliciosa) mandarin.	the present study envisages the influence of essential oils namely lemon grass, eucalyptus, clove and neem on kinnow mandarin with the objective to combat major post harvest diseases and to prolong its availability for longer time in the season. for this, in vitro and in vivo studies were conducted. poisoned food technique was used for in vitro studies, and for in vivo studies, kinnow fruit were pre-inoculated with pathogens (penicillium digitatum and p. italicum), treated with different essenti ...	2015	25829604
correlation between ionic radii of metals and thermal decomposition of supramolecular structure of azodye complexes.	an interesting azodye heterocyclic ligand of copper(ii), cobalt(ii), nickel(ii) and uranyl(ii) complexes have been synthesized by the reaction of metal salts with 5-(2,3-dimethyl-1-phenylpyrazol-5-one azo)-2-thioxo-4-thiazolidinone (hl) yields 1:1 and 1:2 (m:l) complexes depending on the reaction conditions. the elemental analysis, magnetic moments, spectral (uv-vis, ir, (1)h and (13)c nmr and esr) and thermal studies were used to characterize the isolated complexes. the molecular structures of ...	2015	25150428
antifungal activities of crude extractum from camellia semiserrata chi (nanshancha) seed cake against colletotrichum musae, colletotrichum gloeosporioides and penicillium italicum in vitro and in vivo fruit test.	antifungal activities of crude extractum of nanshancha seed cake (nsc), to inactivate postharvest pathogens were investigated. highest inhibitory rate was found against c. musae, c. gloeosporioides and c. papaya p.henn, which was much stronger than that by tea saponin. compared to tea saponin, effects of nsc extractum was relatively weak and similar on c. gloeosporioides penzig and p. italicum. in an in vivo study, best controlling effects by nsc extractum was found with banana anthracnose disea ...	2015	26674222
effect of led blue light on penicillium digitatum and penicillium italicum strains.	studies on the antimicrobial properties of light have considerably increased due in part to the development of resistance to actual control methods. this study investigates the potential of light-emitting diodes (led) blue light for controlling penicillium digitatum and penicillium italicum. these fungi are the most devastating postharvest pathogens of citrus fruit and cause important losses due to contaminations and the development of resistant strains against fungicides. the effect of differen ...	2015	26288067
preparation of b-cyclodextrin-thiabendazole-piperonyl butoxide supramolecular complex and its activity against blue and green mould decay on inoculated satsuma fruit.	the supramolecular complex of β-cyclodextrin-thiabendazole-piperony butoxide (βcd-tbz/pbo) was prepared and its structure was characterized by 1h nmr. additionally, the antifungal activity of βcd-tbz/pbo was investigated in comparison with the commercially available thiabendazole (tbz) fungicide by in vitro tests and on artificially inoculated 'okitsu' satsuma fruit dipped in water at 20 degrees c or at 50 degrees c to control postharvest blue (penicillium italicum) and green mould (p. digitatum ...	2015	27141746
semi-synthesis of new antimicrobial esters from the natural oleanolic and maslinic acids.	in this article, we report an effective procedure for the selective isolation of oleanolic acid 1 and maslinic acid 2 (3.4 and 8.5mg/g dw, respectively) from pomace olive (olea europaea l.) using an ultrasonic bath, and the synthesis of a series of new triterpenic acid esters. the compounds were characterized by their spectral data and were evaluated for their antimicrobial activity. among the compounds tested, those having sulfur and chlorine atoms were found to be antibacterial. they showed ac ...	2015	25863603
effect of cd⁺² on phosphate solubilizing abilities and hydrogen peroxide production of soil-borne micromycetes isolated from phragmites australis-rhizosphere.	the aims of this work were to evaluate the phosphate-solubilization and hydrogen peroxide (h2o2) production by the soil-borne micromycetes, aspergillus japonicus, penicillium italicum and penicillium dipodomyicola, isolated from phragmites australis rhizosphere and to study the effect of several concentrations of cadmium (cd(2+)) on both variables. our results showed that p. italicum achieved a higher p-solubilization and h2o2 production than a. japonicus and p. dipodomyicola, as only p. italicu ...	2016	26646403
synthesis of oxylipin mimics and their antifungal activity against the citrus postharvest pathogens.	nine oxylipin mimics were designed and synthesized starting from d-mannose. their antifungal activity against three citrus postharvest pathogens was evaluated by spore germination assay. the results indicated that all the compounds significantly inhibited the growth of penicillium digitatum, penicillium italicum and aspergillus niger. the compound (3z,6z,8s,9r,10r)-octadeca-3,6-diene-8,9,10-triol (3) exhibited excellent inhibitory effect on both penicillium digitatum (ic50 = 34 ppm) and penicill ...	2016	26907241
antifungal effect of chitosan as ca(2+) channel blocker.	the aim of this study was to investigate antifungal activity of a range of different molecular weight (mw) chitosan against penicillium italicum. our results demonstrate that the antifungal activity was dependent both the mw and concentration of the chitosan. among a series of chitosan derived from the hydrolysis of high mw chitosan, the fractions containing various sizes of chitosan ranging from 3 to 15 glucosamine units named as chitooligomers-f2 (co-f2) was found to show the highest antifunga ...	2016	27298599
use of active extracts of poplar buds against penicillium italicum and possible modes of action.	antifungal components, from poplar buds active fraction (pbaf) against penicillium italicum, the causal agent of blue mold in citrus fruits, were identified and possible action modes were investigated. pinocembrin, chrysin and galangin were determined as active components in pbaf, using hplc and hplc-ms analysis. the antifungal activity is stable at temperatures ranging from 4 °c to 100 °c and ph levels ranging from 4 to 8. in the presence of pbaf, the hyphae become shriveled, wrinkled and the c ...	2016	26593534
monosubstituted benzene derivatives from fruits of ficus hirta and their antifungal activity against phytopathogen penicillium italicum.	ficus hirta, a widely consumed food by hakka people, has been reported to show potent antifungal activity against phytopathogen penicillium italicum. however, there is no report of chemical constituents responsible for the antifungal activity. in the current study, nine monosubstituted benzene derivatives, including three new derivatives (1-3), were isolated from the fruits of f. hirta. the structures of these isolates were elucidated on the basis of the analysis of spectroscopic data (mass spec ...	2016	27381890
antifungal indole alkaloids from winchia calophylla.	ten indole alkaloids (1-10) were obtained from an antifungal extract of winchia calophylla, of which two (2 and 4) were new. n(4)-methyl-10-hydroxyl-desacetylakuammilin (2) was an akuammiline-type indole alkaloid. n(1)-methyl-echitaminic acid (4) was an unusual zwitterion with a basic vincorine-type skeleton. this is the first report of 10 in w. calophylla. the structures of all of the compounds were determined based on spectroscopic data, and their bioactivities were assessed. compound 1 showed ...	2016	27002397
optimization of a protective medium for freeze-dried pichia membranifaciens and application of this biocontrol agent on citrus fruit.	to optimize a protective medium for freeze-dried pichia membranifaciens and to evaluate biocontrol efficacies of agents against blue and green mould and anthracnose in citrus fruit.	2016	26972894
activity of flavanones isolated from rhododendron hainanense against plant pathogenic fungi.	in a search for naturally occurring antimicrobial compounds in medicinal plants and herbs, seven flavanones were isolated from the aerial parts of rhododendron hainanense and were tested for their antimicrobial activities against six bacteria and six plant pathogenic fungi. within the series of flavanones tested, farrerol (1) displayed moderate antibacterial activities against bacillus cereus, b. subtilis, pseudomonas aeruginosa, staphylococcus aureus, escherichia coli and erwinia carotovora, wi ...	2016	27319130
the effect of locust bean gum (lbg)-based edible coatings carrying biocontrol yeasts against penicillium digitatum and penicillium italicum causal agents of postharvest decay of mandarin fruit.	strains belonging to wickerhamomyces anomalus, metschnikowia pulcherrima and aureobasidium pullulans species were tested in vitro as biocontrol agents (bcas) against the post-harvest pathogenic molds penicillium digitatum and penicillium italicum. moreover, studies aimed at screening the antifungal activity of selected yeast strains in vivo conditions against p. digitatum and p. italicum, and investigated the efficacy of a polysaccharidic matrix, locust bean gum (lbg), enriched with the tested b ...	2016	27217363
identification and antifungal activity of compounds from the mangrove endophytic fungus aspergillus clavatus r7.	two new coumarin derivatives, 4,4'-dimethoxy-5,5'-dimethyl-7,7'-oxydicoumarin (1), 7-(γ,γ-dimethylallyloxy)-5-methoxy-4-methylcoumarin (2), a new chromone derivative, (s)-5-hydroxy-2,6-dimethyl-4h-furo[3,4-g]benzopyran-4,8(6h)-dione (5), and a new sterone derivative, 24-hydroxylergosta-4,6,8(14),22-tetraen-3-one (6), along with two known bicoumarins, kotanin (3) and orlandin (4), were isolated from an endophytic fungus aspergillusclavatus (collection no. r7), isolated from the root of myoporum b ...	2017	28825634
antimicrobial effects of silver nanoparticles synthesized by fatsia japonica leaf extracts for preservation of citrus fruits.	due to their potent antimicrobial activity, silver nanoparticles (agnps) synthesized by biomass might be promising in food preservation, whereas effects of agnps on penicillium italicum-induced rot of citrus fruits have not been investigated. in this study, a novel agnps biosynthesis method was developed based on fatsia japonica leaf extracts. it was revealed that concentrations of leaf extracts, agno3 and nacl affected agnps yields and particle sizes obviously. under the optimized conditions (8 ...	2017	28727146
pharmacophore-based virtual screening of novel inhibitors and docking analysis for cyp51a from penicillium italicum.	sterol 14α-demethylases from cytochrome p450 family (cyp51s) are essential enzymes in sterol biosynthesis and well-known as the target of antifungal drugs. the 3d structure of cyp51a from penicillium italicum (picyp51a) was constructed through homology modeling based on the crystal structure of human cyp51a (pdb: 3ld6). molecular dynamics (md) simulation was operated to relax the initial model and followed by quality assessment using procheck program. on the basis of the docking information on t ...	2017	28379163
the structure-antifungal activity relationship of 5,7-dihydroxyflavonoids against penicillium italicum.	to evaluate the structure-activity relationship of 5,7-dihydroxyflavonoids against p. italicum, we tested the antifungal activity of 23 selected 5,7-dihydroxyflavonoids against spore germination of p. italicum, and the effects of hydroxyl group, hydrogenation, methylation and glycosylation on the antifungal activity are explored. c-4'-oh and c-3-oh are active groups for the 5,7-dihydroxyflavonoids against p. italicum. we find that hydrogenation of the c2/c3 bond decreases the antifungal activity ...	2017	28159264