| detection of plasmodium ovale by the ict malaria p.f/p.v. immunochromatographic test. | | 2001 | 11700187 |
| [not available]. | | 1958 | 13561026 |
| unusual length of a plasmodium ovale infection. | | 1958 | 13608056 |
| localization of alkaline phosphatase in the erythrocytic forms of plasmodium ovale. | | 1962 | 13973314 |
| studies on malaria in chimpanzees. x. the presumed second generation of the tissue phase of plasmodium ovale. | | 1963 | 14015114 |
| [plasmodium ovale in french language african territories]. | | 1963 | 14058232 |
| latent infections with plasmodium ovale malaria. | two cases of plasmodium ovale malaria acquired in west africa appeared as primary delayed attacks after one year's continuous residence in canada. both patients took full prophylactic doses of chloroquine before, during, and for several weeks after exposure. the inadequacy of the 4-aminoquinolines for protection against latent benign tertian malaria is noted, and the use of primaquine is recommended. paroxysms occurred in the evening and were accompanied by severe muscle pain, features considere ... | 1965 | 14296004 |
| [detection of plasmodium ovale in moscow among subjects infected in west africa]. | | 1965 | 14345035 |
| the pre-erythrocytic stage of plasmodium ovale. | | 1955 | 14373852 |
| a comparison of west african and west pacific strains of plasmodium ovale. | | 1955 | 14373853 |
| wide distribution of plasmodium ovale in myanmar. | the presence of plasmodium ovale has never been previously reported in myanmar. using blood samples obtained in many villages across the country between 1996 and 2000, molecular diagnosis of plasmodium species was made with semi- or full-nested polymerase chain reaction (pcr) with species-specific primers, followed by agarose gel electrophoresis to detect amplification products. the presence of p. ovale was also confirmed with the another pcr-based diagnosis, the microtiterplate hybridization (m ... | 2002 | 11903985 |
| [imported malaria in children in 1999. study of the armand-trousseau hospital in paris]. | eighty children were treated at the hospital armand-trousseau (paris, france) for a malaria attack from 1999-01-01 to 2000-02-01. | 2002 | 11998422 |
| effect of primaquine standard dose (15 mg/day for 14 days) in the treatment of vivax malaria patients in thailand. | primaquine (8-aminoquinoline), the only effective drug to prevent relapses of the persistent liver forms of plasmodium vivax and plasmodium ovale, can induce hemolytic anemia in patients with glucose-6-phosphate dehydrogenase (g6pd) deficiency. the severity varies considerably among affected individuals. three hundred and sixty-four plasmodium vivax cases (342 g6pd-normal and 22 g6pd-deficient) were given a 3-day course of chloroquine (total dose 1,500 mg) followed by primaquine 15 mg a day for ... | 2001 | 12041544 |
| plasmodium ovale in south africa. | | 1998 | 9861386 |
| "plasmodium ovale infection in delhi" published in indian journal of pediatrics jan-feb 1999; vol. 66 (1): 143-145. | | 1999 | 10798097 |
| [fourth specie of the malarial parasite in man (plasmodium ovale) and its discovery in the ussr]. | | 1951 | 14837465 |
| plasmodium ovale infections detected by pcr assay in lao pdr. | plasmodium ovate infection was demonstrated in 5 out of 143 inhabitants in a village in lao pdr by blood microscopy and pcr assay. although the specimen confirmed to be positive for p. ovale by microscopical examination was only one, the target sequences in the 18s rrna genes of malaria parasite detected in all of the five cases were consisted with those of p. ovale by the pcr assay. this is the first report concerning the presence of so many cases with p. ovale infection in lao pdr. | 1999 | 10928349 |
| plasmodium ovale species in papua new guinea--lest we forget. | the microscopical diagnosis of plasmodium ovale infection is reviewed and its similarity to plasmodium vivax emphasized. its presence in papua new guinea has been recognized for many years, from a time not long after stephens first described the species in 1922, but it is rarely reported. there is no doubt of its presence in papua new guinea, together with p. falciparum, p. vivax and p. malariae, but its exact prevalence and distribution has not been determined. | 1998 | 10934553 |
| malaria epidemiological situation in italy and evaluation of malaria incidence in italian travelers. | malaria was endemic throughout the country until it was eradicated nearly 50 years ago. since then, mainly imported malaria cases have been reported to the national health service, with an increasing trend. the aim of this study was to present a detailed analysis of the current epidemiological situation of malaria in italy, and to make a first attempt to calculate the incidence of malaria in italian international travelers. | 2001 | 11182603 |
| [triple malaria infection in twin sisters from the democratic republic of congo]. | infections with 3 species of malaria parasites are rarely encountered and observed in less than 0.05% of cases. we came across such an infection in four year-old, monozygote twin sisters, coming from kinshasa (democratic republic of congo). in both of them, parasitemia was low or very low for p. falciparum and p. ovale and of 0.1-0.2% for p. malariae. the twin sisters presented with an iron deficiency anaemia, associated with an heterozygous sickle-cell anaemia and a moderate splenomegaly. the b ... | 2003 | 12836524 |
| congenital malaria in england; plasmodium ovale. | | 1957 | 13383202 |
| studies on malaria in chimpanzees. iv. plasmodium ovale. | | 1957 | 13458668 |
| plasmodium ovale in liberia. | | 1957 | 13487966 |
| problems in the therapy for imported malaria in the united states. | errors in the diagnosis of imported malaria are increasingly recognized. however, there are few data on the treatment of malaria in the united states. | 2003 | 14504115 |
| plasmepsin 4, the food vacuole aspartic proteinase found in all plasmodium spp. infecting man. | plasmepsins are aspartic proteinases of the malaria parasite, and seven groups of plasmepsins have been identified by comparing genomic sequence data available for the genes encoding these enzymes from plasmodium falciparum, plasmodium vivax, plasmodium knowlesi, plasmodium berghei, and plasmodium yoelii. the food vacuole plasmepsins typified by plasmepsin 4 from p. falciparum (pfpm4) constitute one of these groups. genes encoding the ortholog of pfpm4 have been cloned from plasmodium ovale, pla ... | 2003 | 14550891 |
| procalcitonin serum levels in tertian malaria. | procalcitonin (pct) is closely correlated with parasite burden and clinical outcome in falciparum malaria. the role of pct in tertian malaria has not previously been investigated. | 2003 | 14613513 |
| malaria "epidemic" in quebec: diagnosis and response to imported malaria. | imported malaria is an increasing problem. the arrival of 224 african refugees presented the opportunity to investigate the diagnosis and management of imported malaria within the quebec health care system. | 2005 | 15632404 |
| external quality assessment schemes raise standards: evidence from the ukneqas parasitology subschemes. | the burden of parasitic disease imported into the temperate zone is increasing, and in the tropics remains very high. thus, high quality diagnostic parasitology services are needed, but to implement clinical governance a measure of quality of service is required. | 2003 | 14645352 |
| evaluation of the realart malaria lc real-time pcr assay for malaria diagnosis. | pcr-based methods have advantages over traditional microscopic methods for the diagnosis of malaria, especially in cases of low parasitemia and mixed infections. however, current pcr-based assays are often labor-intensive and not readily quantifiable and have the potential for contamination due to a requirement for postamplification sample handling. real-time pcr can address these limitations. this study evaluated the performance characteristics of a commercial malaria real-time pcr assay (reala ... | 2004 | 14766829 |
| two types of plasmodium ovale defined by ssu rrna have distinct sequences for ookinete surface proteins. | | 2002 | 12106877 |
| diagnostic criteria and risk factors for plasmodium ovale malaria. | plasmodium ovale is a common malaria parasite in africa, but the epidemiology of p. ovale malaria is poorly known. exposure to malaria, parasitemia, and morbidity were monitored for 6 years among the residents of a village in senegal. the relationship between the level of p. ovale parasitemia and fever risk were analyzed, and diagnostic criteria for clinical p. ovale malaria were established. then the relationships between the occurrence of p. ovale clinical malaria and a series of entomological ... | 2002 | 12195357 |
| a retrospective examination of sporozoite-induced and trophozoite-induced infections with plasmodium ovale: development of parasitologic and clinical immunity during primary infection. | a retrospective analysis was made of clinical and parasitologic parameters in patients with induced plasmodium ovale infection to document the initial clinical and parasitologic response and their subsequent development of clinical and parasitologic immunity, and to determine the effect of previous homologous and heterologous malaria on subsequent infection with this parasite. the prepatent periods were relatively uniform. eight patients injected with sporozoites that had been stored frozen had ... | 2002 | 12201582 |
| [two cases of mixed infection of malaria diagnosed by pcr method]. | we here reported two japanese cases of mixed infections of plasmodium species, whose dnas were detected using the pcr test. one case was a 31 year-old male, who presented fever and fatigue, and had a travel history to kenya, cameroon and indonesia. smear test of his peripheral blood found the presence of plasmodium vivax, while nested-pcr diagnosis detected the dnas both p. vivax and plasmodium malariae. the other was a 54 year-old female suffering from general fatigue. she had been treated with ... | 2002 | 12212325 |
| [current data on malaria in metropolitan france]. | epidemiological data from the french national reference center for imported diseases showed that the estimated number of cases of imported malaria in france increased from 5,940 in 1998 to 7,127 in 1999 and 8,056 in 2000. this three-year progression ended in 2001 when the number of estimated cases fell back to 7,223. it was due mainly to the concomitant increase in the number of people traveling to endemic zones especially in africa. in 2000 the median age of patients with imported malaria in fr ... | 2002 | 12244913 |
| the assessment of antimalarial drug efficacy. | antimalarial drug efficacy in uncomplicated malaria should be assessed parasitologically in large, community-based trials, enrolling the age groups most affected by clinical disease. for rapidly eliminated drugs, a 28-day follow-up is needed, but, for slowly eliminated drugs, up to nine weeks could be required to document all recrudescences, and, when possible, the drug levels should also be measured. the who 14-day assessments are neither sensitive nor specific. in tropical plasmodium vivax and ... | 2002 | 12377597 |
| detection of imported malaria with the cell-dyn 4000 hematology analyzer. | the sensitivity and specificity of the cell-dyn 4000 hematology analyzer in the diagnosis of imported malaria were studied with samples from patients in an academic hospital setting. the performance of the cell-dyn 4000 hematology analyzer was compared with that of conventional diagnostic methods for malaria. the cell-dyn 4000 hematology analyzer detected hemozoin-containing depolarizing monocytes in 29 of 58 patients with malaria and 2 of 55 patients without malaria. the presence or absence of ... | 2002 | 12454179 |
| transmission of mixed plasmodium species and plasmodium falciparum genotypes. | we studied malaria transmission by comparing parasite populations in humans and mosquito vectors at the household level. blood samples were collected from all inhabitants for microscopic detection of gametocytes and polymerase chain reaction analysis. the next morning, blood-fed resting mosquitoes were collected inside the bed nets used by the individuals surveyed the previous afternoon. after 8 days of maintenance, mosquitoes were dissected, and midguts and salivary glands were recovered for po ... | 2003 | 12641406 |
| automated detection of malaria-associated intraleucocytic haemozoin by cell-dyn cd4000 depolarization analysis. | laboratory tests for malaria are only performed if there is clinical suspicion of the disease, and a missed diagnosis contributes substantially to morbidity and mortality. malaria parasites produce haemozoin, which is able to depolarize light and this allows the automated detection of malaria during routine complete blood count analysis (cbc) with some abbott cell-dyn instruments. in this study, we evaluated the cell-dyn cd4000 with 831 blood samples submitted for malaria investigations. samples ... | 2003 | 12641610 |
| avoiding misdiagnosis of imported malaria: screening of emergency department samples with thrombocytopenia detects clinically unsuspected cases. | misdiagnosis of imported malaria is not uncommon and even abnormal routine laboratory tests may not trigger malaria smears. however, blind screening of all thrombocytopenic samples might be a possible way to detect clinically unsuspected malaria cases in the accident and emergency department (aed). | 2003 | 12757689 |
| cross-species regulation of plasmodium parasitemia in semi-immune children from papua new guinea. | malariologists have long been fascinated by the question of whether plasmodium spp. interact in the human host. the first genetic study of the longitudinal dynamics of multiple plasmodium spp. and genotypes in humans has been completed in papua new guinea, where all four plasmodium spp. that infect humans are present. the broad implications of the data from this study are covered here and they show that the total parasite density of plasmodium species oscillates around a threshold and that peaks ... | 2003 | 12798085 |
| use of a rapid, single-round, multiplex pcr to detect malarial parasites and identify the species present. | a new, rapid assay, based on a single-round, multiplex pcr, can be used to detect plasmodium falciparum, p. vivax, p. malariae or p. ovale in human blood. the pcr, which targets the conserved 18s small-subunit rna genes of the parasites, not only permits a malarial infection to be detected but also allows each plasmodium species present to be identified, even in cases of mixed infection. | 2003 | 12803868 |
| a systematic overview of published antimalarial drug trials. | systematic database searches identified 435 antimalarial drug treatment trials, involving 82,616 patients, conducted and published between 1966 and december 2002. of these trials 72% were randomised; 64 (15%) trials involved severe malaria, 47 (11%) studied plasmodium vivax, 3 plasmodium malariae or plasmodium ovale, and the remainder (74%) assessed treatment responses in uncomplicated falciparum malaria. twelve trials (2.7%) specifically evaluated antimalarial treatments in pregnant women. over ... | 2004 | 14964805 |
| evaluation of a new plate hybridization assay for the laboratory diagnosis of imported malaria in italy. | a new molecular diagnostic method "malaria-ibridogen" (amplimedical s.p.a.--bioline division, turin, italy) based on a plate-hybridization assay for the simultaneous detection and identification of human malaria parasites was evaluated in this study. a target dna sequence of the plasmodial 18s ribosomal rna gene was amplified by polymerase chain reaction (pcr) and hybridized in microtiter wells with five biotinylated probes each specific for plasmodium falciparum, p. vivax, p. malariae, p. ovale ... | 2004 | 15164627 |
| recombinant expression and enzymatic subsite characterization of plasmepsin 4 from the four plasmodium species infecting man. | plasmepsin 4 from plasmodium falciparum and orthologs from plasmodium malariae, plasmodium ovale and plasmodium vivax have been expressed in recombinant form, and properties of the active site of each enzyme characterized by kinetic analysis. a panel of chromogenic peptide substrates systematically substituted at the p3, p2, p2' and p3' positions was used to estimate enzyme/ligand interactions in the corresponding enzyme subsites based upon kinetic data. the kinetic parameters kcat, km and kcat/ ... | 2004 | 15287591 |
| low autochtonous urban malaria in antananarivo (madagascar). | the study of urban malaria is an area undergoing rapid expansion, after many years of neglect. the problem of over-diagnosis of malaria, especially in low transmission settings including urban areas, is also receiving deserved attention. the primary objective of the present study was to assess the frequency of malaria among febrile outpatients seen in private and public primary care facilities of antananarivo. the second aim was to determine, among the diagnosed malaria cases, the contribution o ... | 2006 | 16573843 |
| [characteristics of malaria cases diagnosed in edirne province between 1994-2002]. | in this study, the epidemiological characteristics of malaria cases in edirne province were investigated. between the years of 1994-2002, a total of 317,087 blood samples were collected from soldiers in the province with selective active surveillance and from the resident population with active or passive surveillance methods, by the medical staff of malaria control department and health centers, to search the presence of plasmodium. in 281 of them plasmodium spp. were detected, and the characte ... | 2004 | 15293910 |
| molecular analysis of plasmodium ovale variants. | complete dna sequences of the small subunit ribosomal rna (ssurrna) gene and partial sequences of three other loci were obtained from three variant-type and three classic-type plasmodium ovale isolates from southeast asia and compared with genbank-available data. three different ssurrna sequences (pov 1-3) were found in each variant-type isolate, and two different ssurrna sequences (poc 1-2) in each classic-type isolate. pov 1-3 were closer to sequences previously found in the cameroon and mal/m ... | 2004 | 15324543 |
| case report: plasmodium ovale infection acquired in malawi. | malaria due to plasmodium ovale is uncommon outside west africa. a 37-year-old male german who had returned from malawi four months previously presented in september 2003 because of fever recurring every two days. the patient had never been to west africa. microscopy of stained thick and thin blood films revealed p. ovale. this is the first report of a p. ovale infection acquired in malawi, east africa. malaria surveillance centres should monitor the possible emergence of autochtonous transmissi ... | 2004 | 15485706 |
| detection of four plasmodium species in blood from humans by 18s rrna gene subunit-based and species-specific real-time pcr assays. | there have been reports of increasing numbers of cases of malaria among migrants and travelers. although microscopic examination of blood smears remains the "gold standard" in diagnosis, this method suffers from insufficient sensitivity and requires considerable expertise. to improve diagnosis, a multiplex real-time pcr was developed. one set of generic primers targeting a highly conserved region of the 18s rrna gene of the genus plasmodium was designed; the primer set was polymorphic enough int ... | 2004 | 15583293 |
| [malaria in the emergency room. results of the emergency treatment of 137 patients with symptomatic malaria]. | to assess characteristics and outcome of emergency patients with acute malaria. | 2005 | 15662580 |
| ineffectiveness of the binax now malaria test for diagnosis of plasmodium ovale malaria. | | 2005 | 15695736 |
| active-site specificity of digestive aspartic peptidases from the four species of plasmodium that infect humans using chromogenic combinatorial peptide libraries. | two targeted chromogenic octapeptide combinatorial libraries, comprised of 38 pools each containing 361 different peptides, were used to analyze the enzyme/substrate interactions of five plasmepsins. the first library (p1 library) was based on a good synthetic aspartic peptidase substrate [westling, j., cipullo, p., hung, s. h., saft, h., dame, j. b., and dunn, b. m. (1999) protein sci. 8, 2001-2009; scarborough, p. e., and dunn, b. m. (1994) protein eng. 7, 495-502] and had the sequence lys-pro ... | 2005 | 15697202 |
| plasmodium (haemamoeba) cathemerium gene sequences for phylogenetic analysis of malaria parasites. | the dna sequence information on avian malaria parasites of the genus plasmodium is quite limited. at present, sequences of only 6 out of 34 valid species are available. however, sequence data of avian malaria parasites are particularly important with regard to the resolution of the phylogenetic relationships of the most virulent human malaria agent, plasmodium falciparum. the question as to whether p. falciparum originates from avian or from mammalian parasites would contribute to our understand ... | 2005 | 15812672 |
| glucose-6-phosphate dehydrogenase deficiency in two returning operation iraqi freedom soldiers who developed hemolytic anemia while receiving primaquine prophylaxis for malaria. | use of antimalarial prophylaxis continues to be routine practice among military personnel returning from areas where malaria is endemic. primaquine may be used for terminal prophylaxis against plasmodium ovale and plasmodium vivax. serious complications of this regimen are infrequent. we report the occurrence of significant hemolytic anemia for two soldiers returning from operation iraqi freedom. they presented with dark urine, headaches, and classic laboratory findings of hemolysis. both soldie ... | 2005 | 15916292 |
| large sequence heterogeneity of the small subunit ribosomal rna gene of plasmodium ovale in cambodia. | plasmodium ovale malaria has been reported in various countries in southeast asia, but never in cambodia. using a species-specific polymerase chain reaction (pcr) targeting the small subunit (ssu) ribosomal rna (rrna) gene, we detected p. ovale in nearly 4% of the inhabitants of a northeastern cambodian village. plasmodium ovale was associated with at least one other plasmodium species, and two quadruple infections were detected. the diagnosis was confirmed by microscopy and by ssu rrna pcr prod ... | 2005 | 15964956 |
| factors influencing the pattern of imported malaria. | data on imported malaria in industrialized areas are known to be incomplete because of underreporting and lack of homogeneity. these facts and the complexity of factors influencing the transmission of malaria render their interpretation difficult. the relevance of various factors is usually not fully considered, although their impact on recommendations for chemoprophylaxis may be important. | 2005 | 15996451 |
| minor liver profile dysfunctions in plasmodium vivax, p. malaria and p. ovale patients and normalization after treatment. | liver function tests were performed in 61 vivax, 54 malariae and 15 ovale malaria patients who were admitted to bangkok hospital for tropical diseases between 2001 and 2004. the objective of the study was to evaluate changes in hepatic biochemical indices before and after treatment with artemisinin derivatives. on admission and prior to treatment, hepatic dysfunction was found among the 3 groups. serum liver function tests and physical examinations were performed weekly during the 28-day follow- ... | 2006 | 17170571 |
| plasmodium ovale: parasite and disease. | humans are infected by four recognized species of malaria parasites. the last of these to be recognized and described is plasmodium ovale. like the other malaria parasites of primates, this parasite is only transmitted via the bites of infected anopheles mosquitoes. the prepatent period in the human ranges from 12 to 20 days. some forms in the liver have delayed development, and relapse may occur after periods of up to 4 years after infection. the developmental cycle in the blood lasts approxima ... | 2005 | 16020691 |
| plasmodium species mixed infections in two areas of manhiça district, mozambique. | we compared the distribution patterns of individual plasmodium species and mixed-species infections in two geographically close endemic areas, but showing environmental differences. comparisons concerned circulating plasmodium infections in both human and mosquito vector populations in the dry and wet seasons, at a micro-epidemiological level (households). both areas revealed a very high overall prevalence of infection, all year-round and in all age groups. plasmodium falciparum was the predomin ... | 2005 | 16094461 |
| targeting primaquine into liver using chylomicron emulsions for potential vivax malaria therapy. | primaquine (pq) exerts a broad spectrum of activities against various stages of parasitic malaria. it remains as the only drug that destroys late hepatic stages and latent tissue forms of plasmodium vivax and plasmodium ovale. however, systems that can target pq to liver hepatocytes, where malarial sporozoites reside, are needed to minimize the dose-limiting severe toxicities and side-effects caused by pq. recently, a reconstituted artificial chylomicron emulsion was generated using commercially ... | 2005 | 16140485 |
| epidemiology of highland malaria in western kenya. | to investigate the epidemiology of falciparum malaria in workers from a highland tea plantation in western kenya with very seasonally limited malaria transmission to determine what factors are associated with increased risk of malaria transmission in the kenyan highlands. | 2003 | 16167741 |
| failure of primaquine therapy for the treatment of plasmodium ovale malaria. | | 2005 | 16231275 |
| evaluation of a real-time polymerase chain reaction assay for the diagnosis of malaria in patients from thailand. | we compared the diagnosis of malaria in 297 patients from thailand by a real-time polymerase chain reaction (pcr) assay using the lightcycler with conventional microscopy using giemsa-stained thick and thin blood films. the pcr assay can be completed in one hour and has the potential to detect and identify four species of plasmodium in a single reaction by use of melting temperature curve analysis (however, we did not detect plasmodium ovale in this study). blood was collected, stored, and trans ... | 2005 | 16282292 |
| malaria relapse and recrudescence among travellers to the tropics. | this study describes 14 cases of relapse and recrudescence of malaria, treated between 1991 and 2003. in that period, 146 patients were hospitalized in the clinic of the institute in gdynia: 20 women and 126 men. in 103 cases the disease was caused by plasmodium falciparum, in 31 cases by plasmodium vivax, in 5 cases by plasmodium malariae, and in 2 cases by plasmodium ovale. five patients were found to have mixed infections, with either p. falciparum and p. vivax or p. falciparum and p. ovale. ... | 2003 | 14974782 |
| development of a real-time pcr assay for detection of plasmodium falciparum, plasmodium vivax, and plasmodium ovale for routine clinical diagnosis. | a taqman-based real-time pcr qualitative assay for the detection of three species of malaria parasites-plasmodium falciparum, p. ovale, and p. vivax-was devised and evaluated using 122 whole-blood samples from patients who had traveled to areas where malaria is endemic and who presented with malaria-like symptoms and fever. the assay was compared to conventional microscopy and to an established nested-pcr assay. the specificity of the new assay was confirmed by sequencing the pcr products from a ... | 2004 | 15004078 |
| compensatory evolution in the human malaria parasite plasmodium ovale. | the fixation of neutral compensatory mutations in a population depends on the effective population size of the species, which can fluctuate dramatically within a few generations, the mutation rate, and the selection intensity associated with the individual mutations. we observe compensatory mutations and intermediate states in populations of the malaria parasite plasmodium ovale. the appearance of compensatory mutations and intermediate states in p. ovale raises interesting questions about popul ... | 2004 | 15020451 |
| [malaria. primary symptoms: fever, headache, nausea, vomiting, diarrhea]. | | 2006 | 16523989 |
| primaquine-induced differential gene expression analysis in mice liver using dna microarrays. | primaquine (pq), a clinically important derivative of 8-aminoquinoline used against the hepatic stages (hypnozoites) of plasmodium vivax and plasmodium ovale, was studied to evaluate and compare between mrna expression, and biochemical and histological parameters of hepatic stress in adult swiss mice (mus musculus). following single oral dose of pq (40 mg/kg, bw), alanine aminotransferase (alt) and aspartate aminotransferase (ast) along with hematoxylin and eosin stained liver sections did not s ... | 2007 | 17686563 |
| epidemiology of malaria in new halfa, an irrigated area in eastern sudan. | a prospective study investigated the epidemiology of malaria in an agricultural area in eastern sudan from november 1999 to june 2000 (1 irrigation and 1 dry season). in monthly parasite surveys, 99/ 1539 blood films from 190 individuals were positive for malaria: 95% for plasmodium falciparum, 3% p. vivax and 2% p. ovale. the slide positive rate (spr) of malaria episodes ranged from 3.7% to 12.8% in different months of the survey, with a peak in january. there was no significant difference in s ... | 2005 | 16602473 |
| stronger host response per parasitized erythrocyte in plasmodium vivax or ovale than in plasmodium falciparum malaria. | fever tends to start at a lower level of parasitemia in plasmodium vivax or ovale than in p. falciparum malaria, but hyperparasitemia and complications are more likely to occur in p. falciparum malaria. therefore, we compared the relationship between parasitemia and host response parameters before therapy in 97 patients with p. faciparum malaria (18 with complications), and 28 with p. vivax or ovale malaria. | 2006 | 16772003 |
| moderate transmission but high prevalence of malaria in madagascar. | malaria transmission remains poorly documented in areas of low transmission. a study has been carried out over two consecutive years in analamiranga, a village located at an altitude of 885m on the western edge of the malagasy highlands, with the aim of generating and updating malariometric indexes for both mosquitoes and schoolchildren. in this village, no vector control measures were performed during the study period nor during previous decades. mosquitoes were collected monthly when landing o ... | 2006 | 16842796 |
| parasites resembling plasmodium ovale in strains of plasmodium vivax. | | 1949 | 18142530 |
| detection and identification of human plasmodium species with real-time quantitative nucleic acid sequence-based amplification. | decisions concerning malaria treatment depend on species identification causing disease. microscopy is most frequently used, but at low parasitaemia (<20 parasites/mul) the technique becomes less sensitive and time consuming. rapid diagnostic tests based on plasmodium antigen detection do often not allow for species discrimination as microscopy does, but also become insensitive at <100 parasites/microl. | 2006 | 17018138 |
| [severe imported malaria. the experience of the military hospital of marrakech]. | incidence of severe imported malaria increases with the multiplication of humanitarian and military missions in malarial endemic areas. the purpose of this study was to describe the demographic, clinical, therapeutic and outcome aspects of 9 cases which have been hospitalized in the intensive care unit and medecine service of the military hospital of marrakech, between january 2001 and december 2004. out of 68 patients admitted with symptomatic malaria during this period, 9 cases were considered ... | 2006 | 17040884 |
| a case of imported plasmodium ovale malaria. | there have been reports in korea of imported malaria cases of four plasmodium species, but there has been no report of imported plasmodium ovale malaria confirmed by molecular biological methods. we report an imported case of that was confirmed by wright-giemsa-stained peripheral blood smear and nested polymerase chain reaction targeting the small subunit ribosomal rna gene. the amplified dna was sequenced and compared with other registered p. ovale isolates. the isolate in this study was a memb ... | 2006 | 17043432 |
| tertian malaria (plasmodium vivax and plasmodium ovale) in two travelers despite atovaquone-proguanil prophylaxis. | there is limited data regarding the efficacy of prophylaxis with atovaquone/proguanil (a/p) against non-falciparum malaria in travelers. two cases, one plasmodium vivax infection and another plasmodium ovale infection, in travelers despite a/p prophylaxis are presented. | 2006 | 17107431 |
| failure of atovaquone/proguanil to prevent plasmodium ovale malaria in traveler returning from cameroon. | we report a case of a patient returning from cameroon who developed plasmodium ovale malaria, despite atovaquone/proguanil (ap, malarone) prophylaxis, which is widely used for the prevention of chloroquine-resistant malaria. ap is indeed active only on schizont blood forms of p. ovale but not against liver-stage hypnozoites and does not realize effective prophylaxis against delayed onset of p. ovale malaria. hence, this case illustrates the risk of failure with malarone for the prophylaxis of p. ... | 2008 | 18486067 |
| space-time clustering of childhood malaria at the household level: a dynamic cohort in a mali village. | spatial and temporal heterogeneities in the risk of malaria have led the who to recommend fine-scale stratification of the epidemiological situation, making it possible to set up actions and clinical or basic researches targeting high-risk zones. before initiating such studies it is necessary to define local patterns of malaria transmission and infection (in time and in space) in order to facilitate selection of the appropriate study population and the intervention allocation. the aim of this st ... | 2006 | 17118176 |
| malaria chemoprophylaxis: strategies for risk groups. | the risk of malaria for travelers varies from region to region and depends on the intensity of transmission, the duration of the stay in the area of endemicity, the style of travel, and the efficacy of preventive measures. the decision to recommend chemoprophylaxis to travelers to areas with a low risk of malarial infection is especially difficult because the risk of infection must be balanced with the risk of experiencing side effects. if the risk of side effects by far exceeds the risk of infe ... | 2008 | 18625682 |
| evaluation of a real-time pcr assay for malaria diagnosis in patients from vietnam and in returned travellers. | real-time pcr diagnosis of malaria has advantages over traditional microscopic methods, especially when parasitaemia is low and when dealing with mixed infections. we have developed a new real-time pcr with specific genes in each plasmodium species present only in one copy to identify the four pathogenic plasmodium spp. for humans. the sensitivity was less than 25 parasites/microl. no cross-hybridisation was observed with human dna or among the four plasmodium spp. using lightcycler pcr and conv ... | 2007 | 17150235 |
| [an imported case of mixed malaria caused by plasmodium falciparum and plasmodium ovale.] | malaria caused by plasmodium species is an important parasitic infection in turkey as in the rest of the world. malaria cases originating in our country are caused by p. vivax; those caused by other plasmodium spp. are imported cases. in this article, after work-related travel to cameroon, a patient who acquired specific clinical signs and symptoms of malaria has been evaluated. the major clinical findings of the patient were fever, chills and shaking. after examination of thin and thick blood s ... | 2005 | 17160826 |
| comparison of pcr and microscopy for the detection of asymptomatic malaria in a plasmodium falciparum/vivax endemic area in thailand. | the main objective of this study was to compare the performance of nested pcr with expert microscopy as a means of detecting plasmodium parasites during active malaria surveillance in western thailand. | 2006 | 17169142 |
| plasmodium ovale--a case report from gujarat. | | 2006 | 17175709 |
| outpatient treatment of malaria in recently arrived african migrants. | to describe the clinical features and management of african migrants recently arrived in western australia and subsequently diagnosed with malaria. | 2006 | 17181500 |
| pcr-based detection of plasmodium in anopheles mosquitoes: a comparison of a new high-throughput assay with existing methods. | detection of the four malaria-causing plasmodium species (plasmodium falciparum, plasmodium vivax, plasmodium ovale and plasmodium malariae) within their mosquito hosts is an essential component of vector control programmes. several pcr protocols have been developed for this purpose. many of these methods, while sensitive, require multiple pcr reactions to detect and discriminate all four plasmodium species. in this study a new high-throughput assay was developed and compared with three previous ... | 2008 | 18793416 |
| evaluation and optimization of membrane feeding compared to direct feeding as an assay for infectivity. | malaria parasite infectivity to mosquitoes has been measured in a variety of ways and setting, includind direct feeds of and/or membrane feeding blood collected from randomly selected or gametocytemic volunteers. anopheles gambiae s.l is the main vector responsible of plasmodium falciparum transmission in bancoumana and represents about 90% of the laboratory findings, whereas plasmodium malariae and plasmodium ovale together represent only 10%. | 2008 | 19055715 |
| prevalence of plasmodium spp. in malaria asymptomatic african migrants assessed by nucleic acid sequence based amplification. | malaria is one of the most important infectious diseases in the world. although most cases are found distributed in the tropical regions of africa, asia, central and south americas, there is in europe a significant increase in the number of imported cases in non-endemic countries, in particular due to the higher mobility in today's society. | 2009 | 19138412 |
| uk malaria treatment guidelines. | malaria is the tropical disease most commonly imported into the uk, with 1500-2000 cases reported each year, and 10-20 deaths. approximately three-quarters of reported malaria cases in the uk are caused by plasmodium falciparum, which is capable of invading a high proportion of red blood cells and rapidly leading to severe or life-threatening multi-organ disease. most non-falciparum malaria cases are caused by plasmodium vivax; a few cases are caused by the other two species of plasmodium: plasm ... | 2007 | 17215045 |
| [false-negative result with the rapid diagnostic test in plasmodium ovale infection]. | | 2009 | 19386395 |
| malaria and pregnancy: the perspective in pakistan. | to study the effects of malaria on pregnancy outcome. | 2007 | 17319413 |
| genetic polymorphisms influence plasmodium ovale pcr detection accuracy. | detection of plasmodium ovale by use of a nested pcr assay with a novel plasmodium ovale primer set was superior to detection of plasmodium ovale by real-time pcr assays. nested pcr was also better at detecting p. malariae. the detection of p. ovale in many patients first admitted >2 months following their return to italy indicated that p. ovale relapses are common. | 2007 | 17360843 |
| the diagnosis of malaria and identification of plasmodium species by polymerase chain reaction in turkey. | more than half of the world's population is exposed to malaria in approximately 100 countries. rapid diagnosis and correct treatment of cases are the main objectives of control programs in malaria endemic areas. we have developed a pcr method to determine the presence of plasmodium dna in blood. the method can also identify the species of the plasmodium by restriction enzyme analysis of the amplified product. we evaluated the performance of this method in the diagnosis of malaria suspected cases ... | 2007 | 17434795 |
| [severe imported malaria: the experience of the avicenna military hospital of marrakech]. | incidence of severe imported malaria increases with the multiplication of humanitarian and military missions in malarial endemic areas. the purpose of this study was to describe the demographic, clinical, therapeutic and outcome aspects of 9 cases which have been hospitalized in the intensive care unit and medecine service of the military hospital of marrakech, between january 2001 and december 2004. out of 68 patients admitted with symptomatic malaria during this period, 9 cases were considered ... | 2006 | 17446159 |
| chimpanzee malaria parasites related to plasmodium ovale in africa. | since the 1970's, the diversity of plasmodium parasites in african great apes has been neglected. surprisingly, p. reichenowi, a chimpanzee parasite, is the only such parasite to have been molecularly characterized. this parasite is closely phylogenetically related to p. falciparum, the principal cause of the greatest malaria burden in humans. studies of malaria parasites from anthropoid primates may provide relevant phylogenetic information, improving our understanding of the origin and evoluti ... | 2009 | 19436742 |
| evaluation of the sd fk70 malaria ag plasmodium vivax rapid diagnostic test in a non-endemic setting. | for clinical and epidemiological reasons, it is interesting to diagnose non-falciparum malaria to the species level. this retrospective study assessed the performance of the sd bioline malaria antigen pv test (fk70), a two-band immunochromatographic test detecting plasmodium vivax-specific lactate dehydrogenase, on samples of international travellers in a non-endemic setting. | 2009 | 19519915 |
| alpha-substituted norstatines as the transition-state mimic in inhibitors of multiple digestive vacuole malaria aspartic proteases. | the impact of moving the p1 side-chain from the beta-position to the alpha-position in norstatine-containing plasmepsin inhibitors was investigated, generating two new classes of tertiary alcohol-comprising alpha-benzylnorstatines and alpha-phenylnorstatines. twelve alpha-substituted norstatines were designed, synthesized and evaluated for their inhibitory potencies against plasmepsin ii and the plasmepsin iv orthologues (pm4) present in the digestive vacuole of all four plasmodium species causi ... | 2009 | 19635672 |
| implementation of a novel pcr based method for detecting malaria parasites from naturally infected mosquitoes in papua new guinea. | detection of plasmodium species in mosquitoes is important for designing vector control studies. however, most of the pcr-based detection methods show some potential limitations. the objective of this study was to introduce an effective pcr-based method for detecting plasmodium vivax and plasmodium falciparum from the field-caught mosquitoes of papua new guinea. | 2009 | 19646275 |
| longitudinal survey of malaria morbidity over 10 years in saharevo (madagascar): further lessons for strengthening malaria control. | madagascar has been known for having bio-geo-ecological diversity which is reflected by a complex malaria epidemiology ranging from hyperendemic to malaria-free areas. malaria-related attacks and infection are frequently recorded both in children and adults living in areas of low malaria transmission. to integrate this variability in the national malaria control policy, extensive epidemiological studies are required to up-date previous records and adjust strategies. | 2009 | 19660116 |
| value of liu's stain in rapid diagnosis of plasmodium ovale infection. | | 2009 | 19751654 |
| late relapse of plasmodium ovale malaria--philadelphia, pennsylvania, november 2004. | approximately 1,300 cases of malaria are reported each year in the united states; nearly all of these cases occur in travelers, many of whom fail to receive or adhere to prescribed chemoprophylaxis or do not follow recommendations for prevention of mosquito bites. malaria can persist if not treated or if treated incorrectly (e.g., with an ineffective drug or an incorrect dosage of an effective drug). early treatment is required to avoid severe illness or death. although malaria typically becomes ... | 2005 | 16340939 |