Publications

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hydroxylation and n-demethylation of clarithromycin (6-o-methylerythromycin a) by mucor circinelloides. 19892529234
microbial transformation of 6-o-methylerythromycin derivatives.mucor circinelloides f. griseo-cyanus ifo 4563 was found to convert 6-o-methylerythromycin a (te-031, a-56268) to (14r)-14-hydroxy-6-o-methylerythromycin a [14r)-14-hydroxy te-031). the tlc and spectral data of the conversion product were perfectly identical with those of an active major metabolite of te-031 in humans (m-5). a related antibiotic, 6-o-methylerythromycin b (tb-010), was able to be similarly transformed to its c-14 hydroxy analogue [14r)-14-hydroxy-6-o-methylerythromycin b, (14r)-1 ...19882971032
a case of pseudoparacoccidioidomycosis: detection of the yeast phase of mucor circinelloides in a clinical specimen.a case is presented in which yeastlike cells resembling the yeast phase of paracoccidioides brasiliensis were observed by microscopic examination of a urine sample. a mold identified as mucor circinelloides was isolated from the specimen. it was converted to the yeast form by cultivation on sabouraud agar incubated in a gaspak jar at 37 degrees c. the isolate was eventually shown not to be related to the patient's illness; however, the superficial resemblance of the yeast phase to p. brasiliensi ...19873574440
effects of pentachlorophenol and some of its known and possible metabolites on fungi.the fungicidal activity of pentachlorophenol and its derivatives against 16 species of fungi representing 14 genera was tested. in relation to pentachlorophenol, no increase in fungistatic activity was found for pentachloroanisole, pentachloronitrobenzene, hexachlorobenzene, pentachlorophenyl acetate, o- and p-chloranil, the three isomeric chlorophenols, 2,6-dichlorophenol, the three isomeric tetrachlorobenzenediols, the three isomeric tetrachlorodimethoxybenzenes, the three isomeric tetrachloro ...19863729403
[studies on growth of the fungus strain mucor circinelloides (1 m). i. forms of the growth (author's transl)].the fungus strain mucor circinelloides (1 m) grew polymorphic with the three forms hyphae, gemmae, and budding cells in nutrition substrate with glucose or n-alkanes as c- and energy source. the forms of the growth were differentiated in the size and colour of the cells and in the mode of formation of biomass. the results were discussed.1979543349
a biochemical explanation for lipid accumulation in candida 107 and other oleaginous micro-organisms.the biochemical explanation for lipid accumulation was investigated principally in candida 107 and, for comparison, in the non-oleaginous yeast candida utilis. there were no significant differences between these two yeasts in their control of glucose uptake; in both yeasts, the rates of glucose uptake were independent of the growth rate and were higher in carbon-limited chemostat cultures than in nitrogen-limited cultures. there was no lipid turnover in either yeast, as judged from [14c]acetate ...197944315
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