Publications

characteristics and sites of infection of eubacterium nodatum, eubacterium timidum, eubacterium brachy, and other asaccharolytic eubacteria.	three new species, eubacterium nodatum, eubacterium timidum, and eubacterium brachy, were described, primarily from subgingival samples taken from patients with moderate and severe adult periodontitis. except for the isolation of e. brachy from a pleuropulmonary infection, these species have not been reported from other infected body sites. we report on the isolation of these species and an undescribed group (d-6) of asaccharolytic eubacteria also found in periodontal disease from numerous diffe ...	1987	3624445
serum antibody reactive with predominant organisms in the subgingival flora of young adults with generalized severe periodontitis.	in the present study we sought to determine whether serum antibody was present against microorganisms which predominate in the subgingival flora of young adults with generalized severe periodontitis (sp). subjects with sp were often seropositive for eubacterium brachy, fusobacterium nucleatum e3c22, and peptostreptococcus micros, whereas subjects with juvenile periodontitis (jp) and subjects with healthy periodontium (hp) were not. both sp and jp subjects were more frequently seropositive for ba ...	1985	3988337
aspartame as a source of essential phenylalanine for the growth of oral anaerobes.	phenylalanine and aspartic acid requirements were determined for 13 species of oral bacteria using the chemically defined medium omiz-w1. none of actinobacillus actinomycetemcomitans, bacteroides forsythus, eikenella corrodens, selenomonas sputigena, treponema pectinovorum, t. socranskii, or wolinella recta required either of these amino acid constituents of aspartame (l-aspartyl-l-phenylalanine methylester). phenylalanine was essential for the growth of capnocytophaga gingivalis, eubacterium ti ...	1993	8514113
phylogeny of oral asaccharolytic eubacterium species determined by 16s ribosomal dna sequence comparison and proposal of eubacterium infirmum sp. nov. and eubacterium tardum sp. nov.	16s rrna gene sequences of eubacterium brachy, eubacterium nodatum, eubacterium saphenum, eubacterium timidum, and two previously unnamed taxa were determined. the results of a phylogenetic analysis indicated that all of the strains sequenced belonged to a deep branch of the low-g+c-content gram-positive group. the levels of 16s ribosomal dna sequence similarity between species were low, suggesting that a number of genera may be represented in this group. the representatives of the two unnamed t ...	1996	8863423
restriction fragment-length polymorphism analysis of 16s rdna from oral asaccharolytic eubacterium species amplified by polymerase chain reaction.	restriction fragment-length polymorphism (rflp) analysis of 16s rdna amplified by polymerase chain reaction was used to generate restriction profiles of the type strains of oral asaccharolytic eubacterium species, that is, eubacterium brachy, eubacterium exiguum, eubacterium lentum, eubacterium minutum, eubacterium nodatum, eubacterium saphenum, eubacterium timidum and 33 asaccharolytic eubacterium strains isolated from oral sites. the 16s rrna gene sequences from isolated genomic dna samples we ...	1998	9573818
cryptobacterium curtum gen. nov., sp. nov., a new genus of gram-positive anaerobic rod isolated from human oral cavities.	novel eubacterium-like isolates, strains 12-3t and kv43-b, which were isolated from the periodontal pocket of an adult patient with periodontal disease and necrotic dental pulp, respectively, were studied taxonomically and phylogenetically. the morphological and differential biochemical characteristics of these organisms are also described in this paper. these organisms were gram-positive, anaerobic, non-spore-forming, rod-shaped bacteria that were inert in most of the conventional biochemical t ...	1999	10425779
description of mogibacterium pumilum gen. nov., sp. nov. and mogibacterium vescum gen. nov., sp. nov., and reclassification of eubacterium timidum (holdeman et al. 1980) as mogibacterium timidum gen. nov., comb. nov.	a new genus, mogibacterium, is proposed for anaerobic, non-spore-forming, gram-positive, rod-shaped bacteria which have been isolated from the periodontal pockets of adult human patients with periodontal disease and infected root canals. the novel isolates, strains d2-18t, ba11a-f and d5-2t, were inert in most of the conventional biochemical tests and phenotypically resemble asaccharolytic eubacterium species. the protein profiles of whole cells on sds-page gels and western immunoblotting reacti ...	2000	10758875
detection of slackia exigua, mogibacterium timidum and eubacterium saphenum from pulpal and periradicular samples using the polymerase chain reaction (pcr) method.	the purpose of this study was to detect slackia exigua from root canal samples using a sensitive pcr amplification method. mogibacterium timidum and eubacterium saphenum were also included because of their culture-difficult properties.	2001	11556514
characterisation of eubacterium-like strains isolated from oral infections.	the genus eubacterium currently includes a heterogeneous group of gram-positive, non-spore-forming anaerobic bacilli, many of which are slow growing, fastidious and generally unreactive in biochemical tests. as a consequence, cultivation and identification of isolates are difficult and the taxonomy of the group remains indifferent. in this study, 105 isolates from odontogenic infections, infections associated with dental implants or saliva from healthy subjects and provisionally assigned to the ...	2001	11699590
gram-positive anaerobic bacilli in human periodontal disease.	the uncertain taxonomy of oral anaerobic gram-positive bacilli and their generally slow growing nature has limited the understanding of their role in periodontal disease. the current objective was to design and use species-specific oligonucleotide probes to investigate the relationship of selected gram-positive anaerobic bacilli to periodontal disease.	2004	15206913
detection frequency of periodontitis-associated bacteria by polymerase chain reaction in subgingival and supragingival plaque of periodontitis and healthy subjects.	the aim of this study was to compare the detection frequencies of 25 bacterial species in subgingival and supragingival plaque of 18 untreated periodontitis subjects and 12 periodontally healthy subjects. genomic dna was extracted from subgingival and supragingival plaque samples, and bacterial detection was performed by polymerase chain reaction of the 16s rrna genes. fourteen bacteria showed no relationship with periodontitis, and 11 of these 14 species were frequently detected (> or =50%) in ...	2004	15491463
the microbiology of the acute dental abscess.	the acute dental abscess is frequently underestimated in terms of its morbidity and mortality. the risk of potential serious consequences arising from the spread of a dental abscess is still relevant today with many hospital admissions for dental sepsis. the acute dental abscess is usually polymicrobial comprising facultative anaerobes, such as viridans group streptococci and the streptococcus anginosus group, with predominantly strict anaerobes, such as anaerobic cocci, prevotella and fusobacte ...	2009	19141730
comparisons of subgingival microbial profiles of refractory periodontitis, severe periodontitis, and periodontal health using the human oral microbe identification microarray.	this study compared the subgingival microbiota of subjects with refractory periodontitis (rp) to those in subjects with treatable periodontitis (grs = good responders) or periodontal health (ph) using the human oral microbe identification microarray (homim).	2009	19722792
antibiotic effects on bacterial profile in osteonecrosis of the jaw.	oral diseases (2011) 18, 85-95 objective: oral infection is considered to play a critical role in the pathogenesis of bisphosphonate-related osteonecrosis of the jaw (bronj), and antibiotic therapy has become a mainstay of bronj therapy. this study was aimed to investigate the effect of antibiotics on bacterial diversity in bronj tissues. materials and methods: the bacterial profile from soft tissues associated with the bronj lesion was determined using 16s rrna-based denaturing gradient gel e ...	2012	21883710
detection of mogibacterium timidum in subgingival biofilm of aggressive and non-diabetic and diabetic chronic periodontitis patients.	the aim of the present study was to evaluate the frequency of detection of mogibacterium timidum in subgingival samples of subjects with generalized aggressive periodontitis (gagp) and uncontrolled diabetic and non-diabetic subjects with generalized chronic periodontitis (gchp). 48 patients with gagp, 50 non-diabetic and 39 uncontrolled (glycated hemoglobin >7%) type 2 diabetic subjects with gchp were enrolled in this study. subgingival biofilm were collected from deep pockets (probing depth > 7 ...	2012	24031909
association of synergistetes and cyclodipeptides with periodontitis.	the purpose of this study was to evaluate the microbial community (mc) composition as it relates to salivary metabolites and periodontal clinical parameters in a 21-d biofilm-overgrowth model. subjects (n = 168) were enrolled equally into 5 categories of periodontal status per the biofilm-gingival interface classification. microbial species within subgingival plaque samples were identified by human microbiome identification microarray. whole saliva was analyzed by liquid chromatography-mass spec ...	2015	26198391
microbiomes of endodontic-periodontal lesions before and after chemomechanical preparation.	this study was conducted to evaluate the microbiomes of endodontic-periodontal lesions before and after chemomechanical preparation (cmp).	2015	26521147