Publications

potential of non-mulberry silk protein fibroin blended and grafted poly(є-caprolactone) nanofibrous matrices for in vivo bone regeneration.	an in vivo investigation is conducted to evaluate effectiveness of poly(є-caprolactone) (pcl) nanofibrous matrices, with non-mulberry silk fibroin (nsf) (from antheraea mylitta) inclusion, for bone tissue engineering. inclusion is achieved by either blending nsf with pcl prior to electrospinning substrates or by grafting nsf onto electrospun pcl substrates. proceeding from our previous in vitro results, showing that nsf grafted matrices have an edge when it comes to aiding cellular adhesion and ...	2016	27037780
non-mulberry and mulberry silk protein sericins as potential media supplement for animal cell culture.	silk protein sericins, in the recent years, find application in cosmetics and pharmaceuticals and as biomaterials. we investigate the potential of sericin, extracted from both mulberry bombyx mori and different non-mulberry sources, namely, tropical tasar, antheraea mylitta; muga, antheraea assama; and eri, samia ricini, as growth supplement in serum-free culture medium. sericin supplemented media containing different concentrations of sericins from the different species are examined for attachm ...	2016	27517047
carbon nanofiber reinforced nonmulberry silk protein fibroin nanobiocomposite for tissue engineering applications.	natural silk protein fibroin based biomaterial are exploited extensively in tissue engineering due to their aqueous preparation, slow biodegradability, mechanical stability, low immunogenicity, dielectric properties, tunable properties, sufficient and easy availability. carbon nanofibers are reported for their conductivity, mechanical strength and as delivery vehicle of small molecules. limited evidence about their cytocompatibility and their poor dispersibility are the key issues for them to be ...	2016	27523165
silk fibroin scaffolds with muscle-like elasticity support in vitro differentiation of human skeletal muscle cells.	human adult skeletal muscle has a limited ability to regenerate after injury and therapeutic options for volumetric muscle loss are few. technologies to enhance regeneration of tissues generally rely upon bioscaffolds to mimic aspects of the tissue extracellular matrix (ecm). in the present study, silk fibroins from four lepidoptera (silkworm) species engineered into three-dimensional scaffolds were examined for their ability to support the differentiation of primary human skeletal muscle myobla ...	2016	27878977
genetic variation in ecoraces of tropical tasar silkworm, antheraea mylitta using ssr markers.	the tropical tasar silkworm, antheraea mylitta, polyphagous sericigenous insect mostly found in the tropical areas of india. it is found in these regions as ecotypes or ecoraces. it feeds primarily on plants, a variety of secondary plants like terminalia arjuna and t. tomentosa. tasar culture is a traditional livelihood for lakhs of tribal populace in the areas of jharkhand, chhatisgarh, orissa, maharashtra, andhra pradesh, west bengal and uttar pradesh. in the present study, the genetic diversi ...	2016	27994176
fabrication and characterization of conductive conjugated polymer-coated antheraea mylitta silk fibroin fibers for biomedical applications.	conductive polymers are interesting materials for a number of biological and medical applications requiring electrical stimulation of cells or tissues. highly conductive polymers (polypyrrole and polyaniline)/antheraea mylitta silk fibroin coated fibers are fabricated successfully by in situ polymerization without any modification of the native silk fibroin. coated fibers characterized by scanning electron microscopy confirm the silk fiber surface is covered by conductive polymers. thermogravime ...	2017	28240813
hydroxyapatite reinforced inherent rgd containing silk fibroin composite scaffolds: promising platform for bone tissue engineering.	replacement and repair of ectopic bone defects and traumatized bone tissues are done using porous scaffolds and composites. the prerequisites for such scaffolds include high mechanical strength, osseoconductivity and cytocompatibility. the present work is designed to address such requirements by fabricating a reinforced cytocompatible scaffold. biocompatible silk protein fibroin collected from tropical non-mulberry tasar silkworm (antheraea mylitta) is used to fabricate fibroin-hydroxyapatite (h ...	2017	28285159
elucidation of structural and functional integration of a novel antimicrobial peptide from antheraea mylitta.	we report here the amino acid sequence of an antimicrobial peptide of antheraea mylitta (peptide fraction ii) effectively killed urinary tract associated mdr e. coli (dutta et al., 2016), as gly-gly-gly-gly-gly-gly-his-leu-val-ala. the physicochemical and biological properties of this peptide were evaluated by computational analysis and its isoelectric point, grand average of hydropathicity and boman index values were found to be 6.74, 0.42 and -1.17kcal/mol, respectively. one valid model of pep ...	2017	28302399