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clinico-etiologic correlates of onychomycosis in sikkim.the etiological spectrum of any superficial mycosis is largely dependent on the flora in the immediate environment of the individual. it is influenced by the geographic, climatic and occupational factors. the study is basically to formulate baseline data for the species prevalence of various dermatophytes in patients with onychomycosis attending the central referral hospital, gangtok, sikkim.200919332910
in vitro antifungal drug susceptibilities of dermatophytes microconidia and arthroconidia.arthroconidia have been considered as the primary cause of infection by dermatophytes. however, the in vitro antifungal testing evaluates the responses mainly of microconidia or hyphae, and dermatophytes in vivo often produce arthroconidia, a cellular structure presumably more resistant to antifungals. the aim of this study was to compare the in vitro susceptibility of microconidia and arthroconidia of trichophyton rubrum, trichophyton tonsurans and trichophyton equinum to griseofulvin, itracona ...200818552341
[mycological view of dermatophytes in humans.].dermatophytes are a group of closely related fungi that have the capacity to invade keratinized tissue (skin, hair, and nails) of humans and animals to produce an infection, dermatophytosis, commonly referred to as ringworm. dermatophytoses are common of world wide: in the united states, microsporum audouinii and microsporum canis, once the major agents of tinea capitis, have been superseded by trichophyton tonsurans. since the 1950s, t. tonsuranshas advanced from mexico and the caribbean and is ...199918473586
epidemiologic and clinicomycologic profile of onychomycosis from north india.onychomycosis is an important public health problem because of the increase in immunosuppressive states. large-scale studies in india are scarce, and so the baseline incidence of onychomycosis is not firmly established.200818477149
epidemiology of sporadic (non-epidemic) cases of trichophyton tonsurans infection in japan based on pcr-rflp analysis of non-transcribed spacer region of ribosomal rna gene.a number of cases of trichophyton tonsurans infection have been reported among sportsmen and women participating in wrestling, judo, and sumo wrestling in japan, but there have also been sporadic reports of cases with no history of contact with these sports. a molecular method using restriction enzyme analysis of pcr-amplified fragments targeting the non-transcribed spacer region (nts) of ribosomal rna gene in fungal nuclei was applied to t. tonsurans strains isolated from sporadic cases in japa ...200818503175
susceptibility of dermatophyte isolates obtained from a large worldwide terbinafine tinea capitis clinical trial.our group, in collaboration with seven other laboratories, has recently developed a method to determine the susceptibility of dermatophytes.200818510668
epidemiology of tinea capitis in europe: current state and changing patterns.tinea capitis (scalp ringworm) is the most common dermatophyte infection of the scalp affecting mainly children and rarely adults. the epidemiology of tinea capitis varies within different geographical areas throughout the world. it may occur sporadically or epidemically and an increase in its incidence has been noted over the last few decades. the aim of the study is to obtain a general overview of the current state and changing pattern of tinea capitis in europe. according to the literature, t ...200717681048
[epidemiological correlation between keratinophilic fungi isolated from soil and dermatomycosis agents].this study had the aim of isolating and identifying keratinophilic fungi from soil and correlating them with dermatomycosis agents. according to our results, the predominance of trichophyton tonsurans as a dermatomycosis agent among children in the city of recife, pe, is probably due to children's greater contact with soil.200919802490
dermatophyte infections in cairo, egypt.in this study, we examined dermatophyte infections in patients referred to the department of dermatology, el-houd el-marsoud hospital, cairo, during march 2004 to june 2005. of 506 patients enrolled in this investigation, 403 (79.6%) were clinically diagnosed as having dermatophytoses (age range 6-70 years; males 240; females 163). species identification determined by observation of their macroscopic and microscopic characteristics was complemented with sequencing of the internal transcribed spa ...200918972221
[screening examination of trichophyton tonsurans among judo practitioners at the all japan inter high school championships, saga 2007].this paper presents the results of an examination for trichophyton tonsurans(t. tonsurans)performed by the hairbrush (hb; 90 bristles)method at the all japan inter high school championships, saga 2007. samples were taken from 487 judo practitioners (265 males and 222 females) out of a total of 951. the areas with the highest positive rates were: kyushu 21%(15 participants out of 73 sampled), tohoku 17% (13 out of 77), kinki 16% (14 out of 89), and chubu 13% (12 out of 89). four participants from ...200819001758
changes in frequency of agents of tinea capitis in school children from western china suggest slow migration rates in dermatophytes.tinea capitis is a common dermatophyte infection of the scalp of children in western china, with the gray-patch from being the most prevalent. twenty years ago, the most widespread etiologic agent was reported to be trichophyton violaceum, which was later succeeded by microsporum ferrugineum and trichophyton schoenleinii. in the framework of our recent study, 97 isolates were collected from patients with clinically suspected tinea capitis. identification was performed by conventional methods and ...200818608883
outbreak of tinea gladiatorum in wrestlers in tehran (iran).in recent years, skin diseases in wrestling have finally received the attention they deserve. outbreaks of tinea corporis are often associated with sports involving extensive bodily contact; such sports include wrestling. tinea corporis gladiatorum is primarily caused by trichophyton tonsurans, infecting wrestlers at alarming rates. the management of skin infections in wrestlers and other athletes in sports involving skin-to-skin contact entails numerous challenges, from making an accurate diagn ...200819882012
the emergence of trichophyton tonsurans in port-au-prince, haiti.the occurrence of the anthropophilic dermatophyte trichophyton tonsurans as a frequent causative agent of tinea capitis in several developed countries has been associated with a global rise in its isolation during recent years. while t. tonsurans was never found in haiti before 1988, a sharp increase in the number of isolates of this species from scalp lesions began to be observed in 2005 in port-au-prince, haiti. a prospective study was conducted in port-au-prince from may to november 2006 of 6 ...200918608887
fungistatic effects of optical brightener 220 against trichophyton tonsurans, aspergillus fumigatus and candida albicans.dermatophytes are one of the main causes of dermal infections. moreover, there are some opportunistic fungi such as aspergillus fumigatus (mycelial form) and candida albicans (yeasty form) that in immunosuppressed patients can cause cutaneous disease.200919003591
in vitro pharmacodynamic characteristics of griseofulvin against dermatophyte isolates of trichophyton tonsurans from tinea capitis patients.tinea capitis is the most commonly observed fungal infection in childhood and is primarily caused by the dermatophyte species trichophyton tonsurans, microsporum canis, and trichophyton violaceum. in north america and the united kingdom t. tonsurans is responsible for more than 90% of cases. griseofulvin has been the treatment of choice for tinea capitis for more than 40 years and is the sole oral antifungal agent approved by the fda for the management of tinea capitis. some researchers have exp ...200919212895
changing face of tinea capitis in europe.the aim of this review is to update the latest epidemiological situation in europe, explore recent issues in recognition and emerging opportunities in diagnosis and look at progressions in treatment. papers reviewed have, in the main, been published within the last 2 years.200919262376
epidemiological survey of dermatophytosis in tehran, iran, from 2000 to 2005.cutaneous fungal infections are common in tehran, iran, and causative organisms include dermatophytes, yeasts and non-dermatophyte molds. the prevalence of superficial mycosis infections has risen to such a level that skin mycoses now affect more than 20-25% of the world's population, making them the most frequent form of infection.200919293500
[dermatophytoses due to anthropophilic fungi in cadiz, spain, between 1997 and 2008].cutaneous fungal infections are a major public health problem. the distribution of the dermatophytoses varies between countries and geographical areas. the aim of this study was to determine the incidence, epidemiology, etiology, and clinical course of the dermatophytoses caused by anthropophilic fungi in cadiz, spain, over the past 12 years.201020398600
tinea capitis among children in the columbus area, ohio, usa.tinea capitis is a fungal infection of the hair follicles of the scalp. in the us, the most common organisms have traditionally been trichophyton tonsurans, and occasionally microsporum canis. this study was designed to examine patterns of organisms causing tinea capitis and determine factors associated with infection. a retrospective database analysis was conducted to locate records of patients with tinea capitis from may 2001 to may 2006 at nationwide children's hospital in columbus, oh. descr ...201019302461
epidemiology of fungal scalp infections in the west of scotland 2000-2006.fungal infections of the scalp commonly affect the paediatric population and are caused by dermatophytes which have the ability to invade the keratinised structures of skin, hair and nails. this study analyses the changes in the epidemiology of fungal scalp infections in the west of scotland during the period 2000-2006.200919530495
[dermatophytes isolated in hospital universitario 12 de octubre (madrid, spain).].over a 10 year period (january 1988 - december 1997), 3,241 dermatophyte strains were isolated from 18,465 specimens from patients in whom dermatophytosis was suspected clinically. this represents a 17.5% rate of isolation. trichophyton rubrum (38.44%), microsporum canis (28.75%), epidermophyton floccosum (14.5%) and trichophyton mentagrophytes (13.5%) were the dominant species, and trichophyton tonsurans (2.09%) has emerged, whilst in the previous decade it had virtually disappeared. our study ...199918473578
divergence among an international population of trichophyton tonsurans isolates.trichophyton tonsurans is a widely distributed pathogen that demonstrates a significant degree of genetic and phenetic heterogeneity. to date, the degree of genetic relatedness among geographically segregated isolates has not been explored. this investigation evaluates the extent of genetic variation among an international population of t. tonsurans isolates and examines the relatedness of isolates within and between countries. molecular strain typing was performed on 198 isolates obtained from ...201019609717
[summarization of tinea capitis cases encountered at a clinic in the past 5 years].twelve cases of tinea capitis were encountered at a clinic in kumamoto prefecture between april 2004 and december 2008. patients were boys aged between 2 and 18 in 11 cases, and a woman aged 50 years in 1 case. the pathogen was microsporum canis in 6 cases, and trichophyton tonsurans in 6 cases. in the cases with m. canis , patients were boys aged 2 to 8 years in 5 cases, and the type of disease was non-inflammatory in 5 cases and inflammatory in 1 case. the patients with t. tonsurans were boys ...200919654449
tinea capitis mimicking tufted hair folliculitis.we report a case of tinea capitis mimicking tufted hair folliculitis in a 56-year-old european man, who presented with a 4-year history of pain and erythema in an area of scarring alopecia of the occipital scalp, with scales and tufts of hair emerging from individual follicles. histological examination showed hair plugging, and a dense perifollicular infiltrate of plasma cells, lymphocytes, and neutrophils. there was widespread scarring and fibrosis. bacterial cultures were negative for staphylo ...200919663859
genotyping of trichophyton tonsurans isolate from a japanese boy reveals infection in the usa. 200919236416
[the part of a hospital dermatologist. prevention of trichophyton tonsurans infection].trichophyton tonsurans infection was found first in autumn 2000 in gifu prefecture and spread rapidly in the tokai region. not only direct koh examination but also culture is necessary to diagnose this disease. in order to collect a specimen, i recommend cellophane adhesive tape. during the past 5 years, dermatologists in the tokai area have sent me specimens in an envelope for mycological examination. hyphae were found in all 75 cases in the scales examined. fungal culture revealed 61 cases to ...200818689969
in vitro activity of penicillium chrysogenum antifungal protein (paf) and its combination with fluconazole against different dermatophytes.strains of five dermatophyte species (microsporum canis, microsporum gypseum, trichophyton mentagrophytes, trichophyton rubrum and trichophyton tonsurans) were selected for testing against penicillium chrysogenum antifungal protein (paf) and its combination with fluconazole (fcz). inhibition of microconidia germination and growth was detected with mics of paf ranging from 1.56 to 200 microg ml(-1) when it was used alone, or at constant concentration (100 microg ml(-1)) in combination with fcz at ...200818574706
trichophyton tonsurans-ringworm in an nicu.ringworm is very rarely found in the neonate, especially infants who have been confined from birth to an intensive care unit. we report an infection with the dermatophyte trichophyton tonsurans, the most common cause of tinea capitis in children but not yet described in a premature baby who has never left the nursery. our case illustrates the need to consider this diagnosis among the causes of dermatitis in the newborn, especially in at-risk populations such as indigenous australians. though our ...200919720594
[results of questionnaire survey of trichophyton tonsurans infection in judo clubs registered under the all japan judo federation].it has been seven years since an outbreak of trichophyton tonsurans infection occurred in japan. we have examined the state of t. tonsurans infection by a hairbrush test of athletes and a questionnaire survey of doctors' experience in its treatment, but have not completely grasped the actual state of infection at the sites of judo matches and its treatment or application of preventive measures. subjects and methods: the questionnaire was distributed to the leaders of all judo clubs (10,077 clubs ...200818689970
commonly affected body sites in 92 japanese combat sports participants with trichophyton tonsurans infection.outbreaks of trichophyton tonsurans infection constitute one of the serious problems among combat sports practitioners in japan. to facilitate the diagnosis of individuals at risk, we undertook a study to determine which body sites are most commonly infected. we reviewed medical data, hairbrush culture results and questionnaire information from patients with t. tonsurans infection who were admitted to the dermatology clinic of juntendo university hospital from 2000 to 2004. the study included 92 ...200818793263
tinea capitis in southwest poland.tinea capitis in southwest poland is mainly caused by zoophilic dermatophytes. microsporum canis is the main pathogen, which was demonstrated in all analysed periods between 1977 and 2006 (50.5%-63.2%). recently (2002-2006), a significant (p < 0.05) increase of trichophyton tonsurans isolates was observed, which may be due to increasing migration of polish population in this period. to sum up, the data on the prevalence of tinea capitis in southwest poland resemble the epidemiological situation ...200918793266
comparison between the standardized clinical and laboratory standards institute m38-a2 method and a 2,3-bis(2-methoxy-4-nitro-5-[(sulphenylamino)carbonyl]-2h-tetrazolium hydroxide- based method for testing antifungal susceptibility of dermatophytes.in this study, we determined the utility of a 2,3-bis(2-methoxy-4-nitro-5-[(sulfenylamino)carbonyl]-2h-tetrazolium hydroxide (xtt)-based assay for determining antifungal susceptibilities of dermatophytes to terbinafine, ciclopirox, and voriconazole in comparison to the clinical and laboratory standards institute (clsi) m38-a2 method. forty-eight dermatophyte isolates, including trichophyton rubrum (n = 15), trichophyton mentagrophytes (n = 7), trichophyton tonsurans (n = 11), and epidermophyton ...200818832129
tinea corporis with acute inflammation caused by trichophyton tonsurans.a 13-year-old japanese boy presented with acute skin inflammation on the extremities. he belonged to a judo club of a junior high school in which club tinea capitis and tinea corporis seemed to be prevalent. vesicles and pustules appeared on his right forearm and right leg. they increased in numbers and formed annular lesions. pruritic erythema appeared surrounding these lesions. direct microscopic examination of the lesions detected hyphae, and culture for the fungi yielded yellowish colonies. ...200818837705
trichophyton tonsurans scalp carriage among wrestlers in a national competition in turkey.trichophyton tonsurans tinea gladiatorum is an emerging epidemic among combat-sport athletes across the globe. in the present study, we investigated the prevalence of symptomatic and asymptomatic dermatophytic infections among wrestlers in the national greco-roman championship in turkey. in total, 194 wrestlers from 32 provinces and 72 clubs were examined for scalp, trunk, groin, and toe web dermatophytic infections. we also administered a questionnaire to obtain information on the participants' ...201121472391
prevalence of tinea capitis in southeastern austria between 1985 and 2008: up-to-date picture of the current situation.tinea capitis is the most common dermatophyte infection in childhood, but may rarely occur in adults and the elderly. causative agents vary within different geographical areas as well as during decades. the aim of this study was to evaluate the prevalence and causative agents of tinea capitis in southeastern austria. retrospective analysis of 714 patients diagnosed with tinea capitis seen at the outpatient department of dermatology/medical university of graz during the time period 1985-2008 was ...201119863725
organization and evolutionary trajectory of the mating type (mat) locus in dermatophyte and dimorphic fungal pathogens.sexual reproduction in fungi is governed by a specialized genomic region, the mating type (mat) locus, whose gene identity, organization, and complexity are diverse. we identified the mat locus of five dermatophyte fungal pathogens (microsporum gypseum, microsporum canis, trichophyton equinum, trichophyton rubrum, and trichophyton tonsurans) and a dimorphic fungus, paracoccidioides brasiliensis, and performed phylogenetic analyses. the identified mat locus idiomorphs of m. gypseum control cell t ...201019880755
a clinico-epidemiological study on tinea gladiatorum in iranian wrestlers and mat contamination by dermatophytes.dermatophytosis is still being considered as one of the major public health problems in wrestlers. objectives: to identify the prevalence, clinical pattern, aetiological agents and the predominant transmission route of dermatophytoses in iranian wrestlers, a study was carried out in 2008. in total, 270 wrestlers from eight wrestling salons were evaluated. classical mycological techniques were performed on 135 skin scraping samples of 110 wrestlers suspicious for dermatophytoses and 240 touch pre ...201119917034
a 5-year survey of dermatomycoses in southwest poland, years 2003-2007.the study was performed to analyse the spectrum of dermatomycoses in southwest poland during the period 2003-2007. a total of 10,486 patients were investigated for fungal skin infections by means of native specimen and cultivating procedures. skin scrapings, plucked hairs and nail clippings were examined and identified by direct microscopy and culture. from 2468 patients, 2753 fungi were identified including dermatophytes, yeast and moulds. among the dermatophytes, the most common pathogen isola ...201119925570
screening examination and treatment of trichophyton tonsurans infection in judo athletes affiliated with the university judo federation of tokyo.summary in japan, trichophyton tonsurans infection has become an increasing problem among combat sports participants. we investigated the prevalence of t. tonsurans infection in athletes affiliated to judo clubs in the 21 first division universities that were registered with the university judo federation of tokyo in 2008. study procedures performed by the subjects included (i) completion of a questionnaire concerning lifestyle, risk factors for tinea corporis and medical history; (ii) scrubbing ...200920002880
recovery of dermatophytes in pet grooming tools from veterinary clinics and pet grooming salons.fomites such as brushes and clippers are known to be potential risk factors for the transmission of dermatophytes between pet animals. the aim of this study was to investigate this risk by examining those grooming implements for the presence of any viable dermatophytes.201020137008
efficacy of local herbal therapy in the management of dermatophytosis among primary school children in cross river state, south-south nigeria.as a contribution to the on-going search for alternative, available and affordable treatment of common infections in sub-saharan africa, the efficacy of local herbs, senna alata(linn) and borreria ocymoides (burm), in comparison with conventional drugs, griseofulvin and clotrimazole in the treatment of dermatophytosis among primary school children, was examined in the three districts of cross river state, south-south nigeria. out of 840 pupils screened, 68 (8.1%) were infected, with incidence ra ...200920175416
Molecular Epidemiology of Trichophyton tonsurans Strains Isolated in Japan between 2006 and 2010 and Their Susceptibility to Oral Antimycotics.Trichophyton tonsurans has been isolated among judo practitioners, wrestlers, and sumo wrestlers during an epidemic of tinea corporis and tinea capitis in Japan. A previous study using restriction fragment length polymorphism (RFLP) analysis of the non-transcribed spacer (NTS) region of the ribosomal RNA gene revealed that different sources for the causative fungus in epidemics among judo practitioners and among wrestlers. Many different fungal strains have since been isolated from practiti ...201122116323
the prevalence of infections with trichophyton tonsurans in schoolchildren: the capitis study.although trichophyton tonsurans has become the leading cause of tinea capitis in the united states, reported infection rates vary widely, and prevalence estimates for the pediatric population at large remain poorly characterized.201020403937
onychomycosis observed in children over a 20-year period.summary there are few reports studying the aetiology of onychomycosis in children in spain. to study childhood dermatophyte onychomycosis, a retrospective study of children was carried out, who were <16 years of age with dermatophyte onychomycosis diagnosed between 1987 and 2007. of 4622 nail samples from 3550 patients, 218 came from 181 children up to 16 years old. onychomycosis caused by dermatophytes was demonstrated in 28 (15.5%) cases. trichophyton rubrum (18 cases) was the most prevalent s ...201020406389
[emergence of microsporum audouinii and trichophyton tonsurans as causative organisms of tinea capitis in the dominican republic].tinea capitis affects mainly children. the frequency and causative organism vary from region to region.201020487688
tinea capitis in birmingham: survey of elementary school students.trichophyton tonsurans is currently the leading cause of tinea capitis, but was only introduced into the united states less than six decades ago. in this study, we found a prevalence of 11% in birmingham, alabama, which is similar to earlier reports from other geographic regions. despite previous reports concerning escalation, the prevalence appears to be stable over the past decade.201020553397
evaluation of the association of superficial dermatophytosis and athletic activities with special reference to its prevention and control.this study was conducted to evaluate the association of superficial mycosis and athletic activities with special references to its prevention and control in tehran. participating in various kinds of sports can lead to direct and indirect exposures to and transmission of micro-organisms between athletes and also passive observers.201020636349
prevalence and causative fungal species of tinea capitis among schoolchildren in gabon.summary tinea capitis is endemic among schoolchildren in tropical africa. the objective was to determine the prevalence of symptomatic tinea capitis in schoolchildren in gabon. a cross-sectional study was conducted with 454 children aged 4-17 years, attending a rural school and an urban school. the diagnosis of tinea capitis was based on clinically manifest infection, direct microscopic examination using 20% potassium hydroxide (koh) solution and fungal culture. based on clinical examination, 10 ...201020637052
in vitro antifungal activity of indirubin isolated from a south indian ethnomedicinal plant wrightia tinctoria r. br.acalypha indica, cassia alata, lawsonia inermis, punica granatum, thespesia populnea and wrightia tinctoria are folklore medicines extensively used in the treatment of ringworm infections and skin related diseases in tamil nadu, india.201020691774
semisynthesis and antimicrobial activity of novel guttiferone-a derivatives.six derivatives of guttiferone-a (lfqm-79, 80, 81, 82, 113 and 114) were synthesized and evaluated for their antimicrobial activity against the opportunistic or pathogenic fungi candida albicans (atcc 09548), candida glabrata (atcc 90030), candida krusei (atcc 6258), candida parapsilosis (atcc 69548), candida tropicalis (atcc 750), cryptococcus neoformans (atcc 90012), trichophyton tonsurans, microsporum gypseum and also against the opportunistic and pathogenic gram-positive bacteria staphylococ ...201222401914
[role of cytokine secretion of human keratinocytes in dermatophytosis].the clinical presentation of dermatophytosis depends on species of the infecting fungus. the infections caused by the anthropophilic species tend to be chronic and intractable, and the resultant inflammation is minimal. on the other hand, the infections caused by the geophilic and zoophilic species tend to be self-healing, and the resultant inflammation is more severe. we investigated the role of cytokine secretion of human keratinocyte during dermatophyte infections: arthroderma benhamiae, a zo ...201020716850
experimental researches concerning trichophyton tonsurans, (the ringworm fungus). 188920752604
prevalence and risk factors of onychomycosis in primary school children living in rural and urban areas in central anatolia of turkey.onychomycosis is a world-wide public health concern in children, requiring epidemiological data for different regions for control and prevention.201324177609
chronically recurrent and disseminated tinea faciei/corporis--autoinoculation from asymptomatic tinea capitis carriage.we report clinical findings in a 12-year-old girl with long-term recurrent and disseminated multiple eruptions of tinea faciei and tinea corporis, which persisted for 10 years. mycological examination revealed the dermatophyte trichophyton tonsurans in both scale samples from the body lesions and in brushing samples from her asymptomatic scalp, suggesting that she was an asymptomatic dermatophyte carrier on the scalp, and autoinoculation of the dermatophyte was responsible for the recurrent and ...201020796239
comparative analysis of secreted enzymes between the anthropophilic-zoophilic sister species trichophyton tonsurans and trichophyton equinum.trichophyton tonsurans (tt) and trichophyton equinum (te) are two closely related dermatophytes with very different host preferences. this study was designed to examine the genetic and transcript level variations of secreted enzymes between tt and te. thirty-one genes representing 10 gene families were selected for comparison and complete genomic and cdna sequences were elucidated. sequence analyses of the selected genes identified 104 polymorphisms between the two dermatophytes, 37 of which are ...201020943153
prevalence of tinea pedis, tinea unguium of toenails and tinea capitis in school children from barcelona.to evaluate the prevalence of tinea capitis, tinea pedis, and tinea unguium in children from several schools of barcelona city.200919766517
tinea faciei and tinea capitis in a 15-day-old infant.a case of tinea faciei and tinea capitis in a 15-day-old male infant caused by trichophyton tonsurans is being reported because of its rarity. this may be the youngest infant from india where source of infection was his elder brother who had black dot type of tinea capitis and incubation period in the present case was 7 days.199620947967
clonal outbreak of trichophyton tonsurans tinea capitis gladiatorum among wrestlers in adana, turkey.tinea capitis gladiatorum and tinea corporis gladiatorum caused by the anthropophilic dermatophyte trichophyton tonsurans are well-known clinical entities in individuals involved in combat sports, e.g., wrestlers and judo practitioners. we present an outbreak of trichophyton tonsurans tinea capitis gladiatorum among wrestlers at a boarding school in adana, turkey. fourteen of the 29 wrestlers examined (48.3%) harbored the pathogen, including eight asymptomatic scalp carriers, five with tinea cap ...201019824879
inflammatory tinea capitis due to trichophyton tonsurans in a high school wrestler. 201121605194
carbohydrate profiling of fungal cell wall surface glycoconjugates of trichophyton tonsurans and other keratinophilic filamentous fungi using lectins.various researchers have concluded that lectins are useful reagents for the study of fungal cell wall surface glycoconjugates. in this study, we evaluated the expression of n-acetyl-d-glucosamine, l-fucose, d-galactose and glucose/mannose on the cell wall surface of trichophyton tonsurans and other keratinophilic filamentous fungi, using a simple lectin-binding protocol. the fungal cultures used were isolated from soils obtained from public parks by the hair-bait technique. the lectin assays use ...201121615541
inhibition of growth of trichophyton tonsurans by lactobacillus reuteri.aim:  the aims of this study were to identify antifungal lactic acid bacteria (lab) and characterize their activity against the dermatophyte trichophyton tonsurans. methods and results:  a total of 165 different lab were isolated and initially screened for anti-penicillium expansum activity. five strains, which exhibited strong inhibitory activity, were then tested against the dermatophyte t. tonsurans dsm12285, where they also caused inhibition as observed by large fungal clearing on agar surfa ...201121645181
antidermatophytic activity of pyrazolo[3,4-c]isothiazoles: a preliminary approach on 4-chlorophenyl derivative for evaluation of mutagenic and clastogenic effects on bacteria and human chromosomes in vitro.the antifungal activity of eight pyrazolo[3,4-c]isothiazole derivatives was evaluated on five dermatophytes: three were of an anthropophilic species (i.e., epidermophyton floccosum, trichophyton rubrum, and trichophyton tonsurans) and two were of a geophilic species (i.e., microsporum gypseum and nannizzia cajetani). the new compounds proved to be unlikely effective in inhibiting the growth of the different strains. in general, the fungi parasitic on man were more sensitive than the geophilic sp ...201121649488
tinea capitis and tinea corporis with a severe inflammatory response due to trichophyton tonsurans.trichophyton tonsurans is an anthropophilic dermato-phyte, with a worldwide distribution, although its prevalence varies considerably between different geographical regions. whereas in north america infections due to this fungus are exceptionally common, on the european continent they appear relatively seldom. although t. tonsurans is primarily associated with tinea capitis, it can also be the cause of tinea corporis and tinea unguium. the course of infection is usually only mildly symptomatic. ...201121710105
ganoderma lucidum: a source for novel bioactive lectin.ganoderma lucidum is known for its high medicinal value, clinically used in treatment for various diseases. we have selected this mushroom for isolation of novel bioactive lectin. the isolation procedure comprised of ion-exchange chromatography on deae- cellulose and affinity chromatography on affi-gel blue gel. purified lectin was monomer with a molecular mass of 15 kda, determined by sds-page, gel filtration, maldi-tof. it showed hemagglutinating activity against both human and animal erythroc ...201121728991
antimicrobial and antioxidant activities and chemical characterization of essential oils of thymusvulgaris, rosmarinus officinalis, and origanum majorana from northeastern méxico.there have been no reports of antifungal activity and composition of extracts from thymus vulgaris, rosmarinus officinalis or origanum majorana from northeastern méxico. antifungal activity of these oils against trichophyton rubrum, trichophyton tonsurans, trichophyton mentagrophytes, microsporum gypseum, microsporum canis and epidermophyton floccosum was measured by diffusion assay. additionally, antibacterial and antioxidant activities were evaluated. antibacterial activity against staphylococ ...201525631514
increasing place of trichophyton tonsurans in paris, france: a 15-year retrospective study. 201122059675
trichophyton tonsurans in a family microepidemic.trichophyton tonsurans is a highly transmissible anthropophilic dermatophyte fungus, which invades keratinized tissues. this study reports a case of family microepidemic caused by this dermato phyte. despite their excellent hygiene conditions, it remained active for several years, spreading to all family members. the hypothesis that the fungus was being kept alive in the family home was confirmed after samples collected from it were analyzed. pure cultures of the fungus were isolated and identif ...201122147044
A retrospective study of the management of pediatric kerion in Trichophyton tonsurans infection.Kerion celsi is the inflammatory extreme of tinea capitis, representing a delayed hypersensitivity reaction to the causative dermatophyte. Some authors have advocated the use of oral corticosteroids in patients with kerion formation to inhibit the host inflammatory response and minimize the risk of scarring. This retrospective study analyzed the management and outcome of all children younger than 10 years old presenting to our pediatric dermatology service with tinea capitis resulting in kerion ...201122082462
Extra-Scalp Black Dot Ringworm Caused by Trichophyton tonsurans Among Contact Sports Players.We describe here two patients with tinea corporis exhibiting black dot ringworm (BDR). A cluster of black dots was observed on the extensor surfaces of the extremities of two rather hairy male patients, a 15-year-old judo practitioner and a 26-year-old combined martial arts fighter, during treatment of tinea corporis with topical antimycotics. Direct KOH examination showed that the black dots were composed of degenerated hair with numerous arthroconidia and were indistinguishable from BDR of tin ...201122071663
prevalence of fungal skin infections in iranian wrestlers.fungal infections are one of the most common skin infections. athletes, especially in contact sports such as wrestlers are the group at risk of fungal skin infections (fsi). the aim of this study was to determine prevalence of fsi and some effective factors in wrestlers in tehran, iran.201223785573
tinea faciei in a newborn due to trichophyton tonsurans.we report here the first case of neonatal tinea faciei caused by trichophyton tonsurans in mainland china. the mother of the infant had tinea corpris and tinea capitis while the father had tinea incongnito. the infections in the parents were mycologically confirmed to be due to trichophyton tonsurans. ttinea faciei in the infant was cured after two-week topical use of amorolfine cream. the mother ceased breastfeeding and took oral terbinafine for 4 weeks. no recurrence was observed in the infant ...201223554797
discovery and characterization of a group of fungal polycyclic polyketide prenyltransferases.the prenyltransferase (ptase) gene vrtc was proposed to be involved in viridicatumtoxin (1) biosynthesis in penicillium aethiopicum. targeted gene deletion and reconstitution of recombinant vrtc activity in vitro established that vrtc is a geranyl transferase that catalyzes a regiospecific friedel-crafts alkylation of the naphthacenedione carboxamide intermediate 2 at carbon 6 with geranyl diphosphate. vrtc can function in the absence of divalent ions and can utilize similar naphthacenedione sub ...201222590971
in vitro and in vivo antimicrobial evaluation of alkaloidal extracts of enantia chlorantha stem bark and their formulated ointments.the in vitro and in vivo antimicrobial evaluation of the formulated ointment of alkaloidal extract of enantia chlorantha oliv. (annonaceae) was the concern of this study. the alkaloidal fraction of the stem bark extract was formulated into simple ointment using british pharmacopoeia formula for preparation of simple ointment. agar diffusion and agar dilution methods were used for the in vitro antimicrobial studies. ketoconazole 4000 μg/ml and tioconazole cream 1% were used as reference standards ...201525850210
detection and differentiation of causative organisms of onychomycosis in an ex vivo nail model by means of raman spectroscopy.onychomycosis is worldwide the most prevalent infection of the nail. it is mainly caused by the dermatophytes trichophyton rubrum and trichophyton mentagrophytes and to a lesser extent trichophyton tonsurans. the yeast candida albicans and the mould scopulariopsis brevicaulis can also cause onychomycosis. management of these nail conditions may require appropriate treatment methods and therefore the identification of the causative species can be of importance. however, the determination of agent ...201424286616
identification of fungi species in the onychomycosis of institutionalized elderly.superficial fungal infections are caused by dermatophytes, yeasts or filamentous fungi. they are correlated to the etiologic agent, the level of integrity of the host immune response, the site of the lesion and also the injured tissue.201723793195
dermatophytes isolated from the mosques in tokat, turkey.dermatophytes are a group of fungi that invade keratinized tissues such as the skin, hair and nails. the aim of this study was to investigate the existence of the potential causative agents of dermatophytosis in the mosque area in tokat, turkey. thirty mosques were included in the study. a total of two hundred samples were collected from various parts of carpets and slippers in the mosques. positive cultures were obtained in 144 samples (113 from carpets, 31 from slippers). among the species iso ...201222576940
enzymatic and non-enzymatic virulence activities of dermatophytes on solid media.dermatophytes are keratinophilic fungi causing superficial cutaneous infections that account 20-25% of the global population. as per literature search, there is a dearth in the study on virulence factors of dermatophytes from the indian sub-continent and moreover the association of the virulence factors and the host tissue in vitro helps in understanding the host-pathogen interaction.201728384862
clinicomicrobiological aspects of tinea cruris in madras.a total of 242 patients with clinically diagnosed tinea cruris were screened and 181 (74.7 %) were found to be positive in culture for dermatophytes. 93.9% of infections were caused by trichophyton spp., of which 58.4% were trichophyton rubrum, 5.5% were epidermophyton floccosum, 3.8% were trichophyton tonsurans and we had a single isolate of microsporum gypseum complex. incidence of tinea cruris was higher in males (95.6%) than in females (4.4%). 45% of the cases were recurrent and 38% of cases ...199620948056
trichophyton tonsurans infection in a 12 day-old infant.trichophyton tonsurans infection starting at the age of 12 days is reported. the diagnosis was confirmed by koh examination and culture. onset of superficial fungal infections in infancy is unusual.199520952878
epidemiology of superficial fungal diseases in french guiana: a three-year retrospective analysis.a three-year retrospective analysis of fungi isolated from specimens of patients with superficial fungal infections in french guiana is presented. clinical samples from 726 patients with presumptive diagnoses of onychomycosis (28.2% of the patients), tinea capitis (27.8%), superficial cutaneous mycoses of the feet (22.0%), and of other areas of the body (21.9%), were assessed by microscopic examination and culture. dermatophytes accounted for 59.2% of the isolates, followed by yeasts (27.5%) and ...201121314249
tinea capitis in elderly women: a report of 4 cases.tinea capitis is a condition usually found only in children. however, its epidemiological profile has changed in recent decades, with regard to age at onset and the causative microorganisms. we report the cases of 4 women over 65 years of age diagnosed with tinea capitis. one presented plaques of alopecia with desquamation and the other 3 developed crusted inflammatory lesions. cultures were positive for trichophyton tonsurans (2 patients), trichophyton rubrum, and trichophyton mentagrophytes. t ...201121592449
molecular characterization and in vitro antifungal susceptibility of 316 clinical isolates of dermatophytes in iran.dermatophytosis is a common mycotic infection of the skin, nail, and hair, associated with major public health concern worldwide. various species of dermatophytes show significant differences in susceptibility to antifungals. here, we present the antifungal susceptibility of a large collection of molecularly identified dermatophyte isolates obtained from tropical region of south of iran. a total of 9485 patients clinically suspected to have cutaneous fungal infections were examined. dermatophyto ...201626369643
dermatophytosis: a 16-year retrospective study in a metropolitan area in southern brazil.dermatophytoses are considered a public health problem. the objectives of this study were to determine the evolution of their prevalence in the metropolitan area of porto alegre, brazil, and to analyze the dermatophyte species distribution according to body site and demographic characteristics of the patients.201526322879
a multi-target approach toward the development of novel candidates for antidermatophytic activity: ultrastructural evidence on α-bisabolol-treated microsporum gypseum.multi-target strategies are directed toward targets that are unrelated (or distantly related) and can create opportunities to address different pathologies. the antidermatophytic activities of nine natural skin lighteners: α-bisabolol, kojic acid, β-arbutin, azelaic acid, hydroquinone, nicotinamide, glycine, glutathione and ascorbyl tetraisopalmitate, were evaluated, in comparison with the known antifungal drug fluconazole, on nine dermatophytes responsible for the most common dermatomycoses: mi ...201526132903
isolation of dermatophytes (and other fungi) from human nail and skin dust produced by podiatric medical treatments in australia.podiatric physicians routinely use electric drills for the treatment of nail and skin conditions. the grinding process produces human nail and skin dust that is generally vacuumed into bags in the grinding unit. many of the nails are thought to be mycotic, particularly because they are obtained from patients with symptoms of dermatophyte infections. currently, there is limited information available on the detection of fungi from nail dust samples. herein, we attempt to address this situation and ...201525815649
isolation of dermatophytes (and other fungi) from human nail and skin dust produced by podiatric medical treatments in australia.background: podiatric physicians routinely use electric drills for the treatment of nail and skin conditions. the grinding process produces human nail and skin dust that is generally vacuumed into bags in the grinding unit. many of the nails are thought to be mycotic, particularly because they are obtained from patients with symptoms of dermatophyte infections. currently, there is limited information available on the detection of fungi from nail dust samples. herein, we attempt to address this s ...201525647477
investigation of in vitro activity of five antifungal drugs against dermatophytes species isolated from clinical samples using the e-test method.dermatomycosis is an infection with fungi related to the skin: glabrous skin, hair and/or nails. oral treatment of fungal infections in dermatology has become a preferred modality for the management of these very common conditions. although there are increasing numbers of antifungals available for treatment of dermatophytes, some cases and relapses have been unresponsive to treatment. the determination of fungus in-vitro antifungal susceptibility has been reported to be important for the ability ...201425610290
epidemiology of dermatophytoses in crete, greece.dermatophytoses are among the most frequently diagnosed skin infections worldwide. however, the distribution of pathogenic species and the predominating anatomical sites of infection vary with geographical location and change over time. the aim of this study was to determine the epidemiological and aetiological factors of dermatophytoses in crete, greece over the last 5-year period (2011-2015) and their incidence in relation to the gender and the age of the patients. we compared our findings wit ...201627904054
the changing face of dermatophytic infections worldwide.dermatophytes evolve along with the geography and socioeconomic conditions. epidermophyton floccosum, microsporum audouinii and trichophyton schoenleinii acted as the major pathogens of superficial fungal diseases 100 years ago, but their frequency decreased dramatically since the middle of the twentieth century and they are limited to some less-developed countries nowadays; meanwhile, frequency of trichophyton rubrum, trichophyton interdigitale, trichophyton tonsurans and microsporum canis incr ...201727783316
antidermatophytic action of resorcinol derivatives: ultrastructural evidence of the activity of phenylethyl resorcinol against microsporum gypseum.in this work, we evaluated the antidermatophytic activities of three resorcinol derivatives that have a history of use in dermo-cosmetic applications to discover molecules with multiple dermatological activities (i.e., multi-target drugs), thereby reducing the cost and time necessary for new drug development. the antidermatophytic activities of the three skin lighteners were evaluated relative to the known antifungal drug fluconazole on nine dermatophytes responsible for the most common dermatom ...201627706019
characterization of clinically important dermatophytes in north of iran using pcr-rflp on its region.dermatophytosis is considered as one of the major public health problems in the world. accurate identification of the dermatophytes species is important for recognition of the environment and animal sources of infection. in this survey, 1500 clinical specimens taken from outpatients suspected of dermatophytosis and they were examined by direct microscopy and culture.201627496524
hemolytic activity of dermatophytes species isolated from clinical specimens.hemolytic activity was recently reported for several pathogenic fungal species, such as aspergillus, candida, trichophyton, penicillium and fusarium. based on a number of mechanistic and characterization studies, several fungal hemolysins have been proposed as virulence factors. hemolysins lyse red blood cells resulting in the release of iron, an important growth factor for microbes especially during infection. the requirement of iron in fungal growth is necessary for metabolic processes and as ...201525467819
an ancient plant lawsonia inermis (henna): determination of in vitro antifungal activity against dermatophytes species.world is endowed with a rich wealth of medicinal plants. there is a widespread belief that green medicines are healthier and more harmless or safer than synthetic ones. medicinal plants have been used to cure a number of diseases. the ancient plant lawsonia inermis or henna is used as medicinal plant because of its attributed strong fungicidal, anti-inflammatory, analgesic, antibacterial, virucidal, antiparasitic, antiamoebiasis, astringent, antihemorrhagic, hypotensive, sedative, anticancer eff ...201425442917
mycological pattern of dermatophytosis in and around shimla hills.dermatophytosis is defined as the fungal infection of the skin, hair and nails by a group of keratinophillic fungi known as dermatophytes.201424891658
in vitro susceptibility of dermatomycoses agents to six antifungal drugs and evaluation by fractional inhibitory concentration index of combined effects of amorolfine and itraconazole in dermatophytes.to investigate the antifungal drug susceptibility of fungi responsible for dermatomycoses, minimum inhibition concentration (mic) tests were performed in 44 strains of dermatophytes, including trichophyton rubrum, trichophyton mentagrophytes, trichophyton verrucosum, trichophyton tonsurans, microsporum canis, microsporum gypseum and epidermophyton floccosum, with six antifungal drugs (amorolfine, terbinafine, butenafine, ketoconazole, itraconazole and bifonazole) by broth microdilution assay acc ...201424215461
in vitro activities of antifungal drugs against dermatophytes isolated in tokat, turkey.in this study, we aimed to establish the in vitro antifungal susceptibilities of terbinafine, miconazole, itraconazole, ketoconazole, griseofulvin, and amphotericin b against dermatophyte isolates.201324134487
inactivation of pathogenic dermatophytes by ultraviolet irradiation in swimming pool thermal water.the effect of ultraviolet (uv) radiation from low-pressure mercury lamp against some pathogenic dermatophytes species such as epidermophyton floccosum, trichophyton mentagrophytes, trichophyton rubrum, trichophyton schoenleinii, trichophyton tonsurans and trichophyton violaceum suspended in thermal water was evaluated in laboratory-scale condition at various times. the main results showed that within 120 s of exposure, all species of dermatophytes are completely inactivated, which was evidenced ...201424024625
public health significance of dermatophytes in ismailia and port said provinces, egypt.[corrected] dermatophytes are common in both developed and developing countries, the species involved and the resulting clinical entities vary geographically.201323760076
in vitro antifungal activity of micafungin and caspofungin against dermatophytes isolated from china.the aims of this study are to investigate the in vitro activities of micafungin and caspofungin that are two new echinocandin antifungal drugs against clinically isolated dermatophytes in china and to define mec (minimal effective concentration) as the reading endpoints of this study in accordance with (clinical and laboratory standards institute) clsi m38-a2 reference.201322983900
epidemiology of dermatophytoses in crete, greece between 2004 and 2010.the present work was undertaken in order to study the epidemiology of dermatophytoses in the island of crete, greece, over a 7-year period (2004-2010) and to compare the results with those reported earlier from this region and from other parts of the world.201222648332
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