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[determination of the in vitro bacteriostatic and bactericidal activity of a hexetidine-based pharmeceutic preparation on the bacterial strains from young dental plaque]. 19744471488
anaerobic infection of the paranasal sinuses. 19744148564
a role for cell-mediated immunity in the pathogenesis of periodontal disease. 19744154586
observations on the bacterial flora and pathology of the tongue of sheep deficient in zinc. 19744424066
phosphatase activity of anaerobic organisms.anaerobic organisms were tested for phosphatase activity in different ph ranges. several groups of organisms displayed characteristic patterns. bacteroides fragilis, b. melaninogenicus, and b. ruminicola produced phosphatase with strongest activity at ph 8.6. fusobacterium mortiferum was the only species of this genus to show strong hydrolysis. the enzyme was active in both acid and alkaline ranges. the activity of gram-positive organisms was variable, the most active groups being clostridium pe ...19744363556
extracellular deoxyribonuclease production by anaerobic bacteria.the production of extracellular deoxyribonuclease was examined with anaerobic organisms isolated from clinical specimens. nuclease activity was extraordinarily common. all strains of fusobacterium, including eight species, as well as bacteroides fragilis and b. melaninogenicus, displayed enzyme activity. whereas the gram-positive bacteria were generally less productive, all strains of clostridium perfringens, peptostreptococcus intermedius, and p. anaerobius specifically produced deoxyribonuclea ...19744364608
the normal microbial flora of the mouth. 19744373838
isolation and indentification of anaerobic bacteria in the clinical laboratory. a 2-year experience. 19744597783
bacteremia after tooth extractions studied with the aid of prereduced anaerobically sterilized culture media.both prereduced molten agar and broth and aerobic molten agar and broth were inoculated with blood samples collected from patients with periodontitis, but in otherwise good health, both before and after extraction of two or more teeth. postoperative blood samples from 23 of 25 patients sampled yielded anaerobic and facultative species. colony counts from nine samples yielded from less than 1 to over 100 colonies per ml of blood. organisms detected were species belonging to the genera bacteroides ...19744598226
bacterial microflora of the upper gastrointestinal tract in infants without diarrhoea. 19744208455
adjuvant effects of oral microorganisms on the immunological responses. 19744219133
bacteriological, electron microscopical, and biochemical studies on dento-gingival plaque of moroccan children from an area with low caries prevalence. 19744525486
the effects of preoperative rinsing with cetylpyridinium chloride on bacteremia associated with the surgical removal of impacted third molars. 19744528780
the presence and function of cytochromes in selenomonas ruminantium, anaerovibrio lipolytica and veillonella alcalescens. 19744362619
control of oral flora by hibitane and other antibacterial agents. 19744612717
intrinsic and extrinsic factors influencing the flora of the mouth. 19744612726
antimicrobial considerations in anaerobic infections. 19744822593
the incidence of bacteremia following oral prophylaxis on pediatric patients. 19744519445
isolation and classification of anaerobic bacteria from intact pulp chambers of non-vital teeth in man. 19744522935
[studies on the effect of physical agents, including ultraviolet irradiation, on veillonellophage particles (author's transl)]. 19744535018
a simple and efficient method for the antibiotic sensitivity disk testing of anaerobic bacteria. 19744452753
small-intestinal bacterial flora in dermatitis herpetiformis. 19744210511
[changes of susceptibility of anaerobes to various antibiotics (author's transl)]. 19744215896
metabolic interactions among intestinal microorganisms. 19744217102
accumulation of phosphatidylserine in strictly anaerobic lactate fermenting bacteria. 19751140395
lipid-phase transitions of the strictly anaerobic bacteria veillonella parvula and anaerovibrio lipolytica.as a basis for physicochemical studies on the membranes of the strictly anaerobic bacteria veillonella parvula, anaerovibrio lipolytica, and megasphaera elsdenii, the fatty acyl and alk-1-enyl moieties on the phosphoglycerides of these organism were characterized. uncommon is the high proportion of a heptadecenoic acyl and alk-1-enyl moiety in these three lactate-fermenting bacteria. in contrast to v. parvula and a. lipolytica, m. elsdenii contains high amounts of branched-chain acyl and alk-1-e ...19751194242
iron-sulphur systems in some isolated multi-component oxidative enzymes. 19751237425
cell wall composition and incorporation of radio-labelled compounds by veillonella alcalescens.the cell wall of veillonella alcalescens was shown to have a typically gram-negative appearance and composition. the wall contains 24% lipid, 0.8% phosphorus, and 6.8% hexosamine. it is estimated to contain about 5% murein, unlike the 24% reported by other for veillonella parvula. the amounts of 19 amino acids, including diaminopimelic acid, were determined. though veillonella sp. cannot metabolize sugars for energy, v. alcalescens incorporates ribose and fructose by separate, specific mechanism ...19751240789
evaluation of human oral organisms and pathogenic streptococcus for production of iga protease.iga protease is a proteolytic enzyme found in whole human saliva and in dental plaque that cleaves both secretory and myeloma iga of human origin to yield intact fabalpha and fcalpha fragments. to determine which bacteria are capable of producing this enzyme, we have examined a variety of strains normally found in the human oral cavity and a number of streptococci of known lancefield group serotype. streptococci of groups a, b, c, d, f, g, h, m, and n, streptococcus mutans, streptococcus sanguis ...19751168676
characterization of a naturally occurring diamine auxotroph of veillonella alcalescens.veillonella alcalescens strain atcc 17745 was shown to require putrescine or cadaverine for growth. none of the other compounds tried, including magnesium and spermidine, were able to substitute for the diamines. studies with labeled diamines showed that spermidine was made from putrescine in this organism. a polyamine analogous to spermidine, but made from cadaverine, was not found. a combination of growth experiments and chemical assays suggested that protein synthesis was limited in diamine-s ...19751194234
susceptibility of anaerobic bacteria to metronidazole: relative resistance of non-spore-forming gram-positive baccilli.susceptibility of 358 clinical isolates of obligate anaerobes to metronidazole was determined by an agar-dilution technique. only 66% of all isolates were inhibited by 6.25 mug/ml, whereas 30% required larger than or equal to 50 mug/ml. considerable variation in susceptibility was observed among different genera and species of bacteria. fusobacterium was most senstitive, followed by clostridium, bacteroides and peptococcus, peptostreptococcus, veillonella and acidaminococcus, and non-spore-formi ...1975163867
total viable count and differential count of vibrio (campylobacter) sputorum, fusobacterium nucleatum, selenomonas sputigena, bacteroides ochraceus and veillonella in the inflamed and non inflamed human gingival crevice. 1975129552
elective medium for the direct count of vibrio (campylobacter) fusobacteria, bacteroides, selenomonas and veillonella in the gingival crevice flora. 1975127034
rapid screening of veillonella by ultraviolet fluorescence.among 51 strains of anaerobic gram-negative cocci belonging to the family veillonellaceae, all strains of veillonella (v. parvula and v. alcalescens) displayed red fluorescence under long-wave (366 nm) ultraviolet light, whereas no acidaminococcus or megasphaera demonstrated fluorescence. in contrast to bacteroides melaninogenicus, growth of veillonella does not require hemin and menadione, and flourescence is rapidly lost upon exposure to air. the fluorescent component of a strain of v. parvula ...19751419
amino acid transport in membrane vesicles of obligately anaerobic veillonella alcalescens.membrane vesicles of veillonella alcalescens, grown in the presence of l-lactate and kno-3, actively transport amino acids under anaerobic conditions in the presence of several electron donors and the electron acceptor nitrate. the highest initial rates of uptake are obtained with l-lactate, followed by reduced nicotinamide adenine dinucleotide, glycerol-1-phosphate, formate, and l-malate.. the membrane vesicles contain the dehydrogenases for these electron donors, and these enzymes are coupled ...1975164433
purification and regulatory properties of pyruvate kinase from veillonella parvula.the nonglycolytic, anaerobic organism veillonella parvula m4 has been shown to contain an active pyruvate kinase. the enzyme was purified 126-fold and was shown by disc-gel electrophoresis to contain only two faint contaminating bands. the purified enzyme had a ph optimum of 7.0 in the forward direction and exhibited sigmoidal kinetics at varying concentrations o-f phosphoenol pyruvate (pep), adenosine 5'-monophosphate (amp), and mg-2+ ions with s0.5 values of 1.5, 2.0, and 2.4 mm, respectively. ...1975238944
continuous monitoring of ph and eh in bacterial plaque grown on a tooth in an artificial mouth.apparatus which enables the simultaneous continuous monitoring of ph and eh of bacterial dental plaque as it develops on a tooth surface in an artificial mouth is described. details of the electrodes used, monitoring equipment, and culture conditions are given. preliminary results are given showing the eh and ph values of plaque produced in vitro to be in close agreement with readings reported for plaque in vivo. the effect of the incorporation of 1 per cent sucrose in the medium on these par ...1975234712
activation by some t-independent antigens and b cell mitogens of the alternative pathway of the complement system.a number of t-independent antigens and b cell mitogens were examined for their ability to activate c3 via the alternative pathway of the complement system. loss of hemolytically active c3, generation of anaphylatoxin activity, and immunoelectrophoretic conversion of c3 and factor b, were checked in normal and c4-deficient guinea pig serum, and, in some cases, in normal human serum. as judged by their activity in these assays, 10 lipopolysaccharides of different origin and constitution, pneumococ ...1975239062
antibiotic treatment of oral anaerobic infections. 19751056466
disk susceptibility testing of slow-growing anaerobic bacteria.the susceptibility of 55 strains of slow-growing anaerobes to eight clinically useful or potentially useful antibiotics was determined by agar dilution and disk diffusion tests. strains of the genera peptococcus, peptostreptococcus, megasphaera, veillonella, eubacterium, bifidobacterium, clostridium, and fusobacterium were included. all strains were susceptible to chloramphenicol, but varied in their susceptibility to penicillin, lincomycin, clindamycin, tetracyclines, and vancomycin. correlatio ...19751137353
susceptibility of anaerobic bacteria to carbenicillin, cefoxitin, and related drugs.the agar dilution technique was used for determination of the bacteriostatic activity of carbenicillin, penicillin g, cefazolin, cephaloridine, cefoxitin, and cephalothin agaomst a variety of anaerobic bacteria. carbenicillin showed a high level of activity at a concentration of smaller than or equal to 100 mug/ml; only five of 123 strains of bacteroides fragilis, one strain of bifidobacterium eriksonii, and one strain of clostridium bifermentans were resistant to a concentration of larger than ...1975804023
[changes of antimicrobial susceptibility of anaerobic bacteria from clinical specimens (author's transl)].the susceptibility to several commonly used antimicrobial agents was examined on approximately 900 isolates of various anaerobes from clinical specimens between october 1965 to may 1975, and the changes of susceptibility were investigated. antimicrobial agents tested were penicillin g (pc-g), ampicillin (ab-pc), cephaloridine (cer), erythromycin (em), josamycin (jm), lincomycin (lcm), clindamycin (cldm), chloramphenicol (cp) and tetracycline (tc). and thiamphenicol (tp) and doxycycline (dotc) we ...19751042183
the faecal flora of children in the united kingdom.the faecal flora of 55 children (aged 8 days to 8 years) and 16 adults was determined. all the children were artificially fed from birth. the faecal flora of the youngest age group was generally less complex and less predictable than that of adults. some bacterial groups commonly found in adult stools, for example bacilli, lactobacilli and yeasts, were rarely found in the youngest infants. most of the changes towards the adult pattern took place between 4 and 12 months. the faecal flora of child ...19751056968
variations in microbial and biochemical components of four-day plaque during a four-week controlled diet period.variation in microbial and biochemical components of human four-day plaque was studied in seven subjects who were maintained on a high-sucrose diet during a four-week period. significant changes in populations of lactobacilli dextranase-producing organisms, streptococcus mutans, and s sanguis occurred during this period.19751057555
induction of cellular hypersensitivity to oral microorganisms in guinea-pigs. 19751056763
transient bacteremia associated with barium enema.a group of 175 patients had barium enema. pour-plate blood cultures were obtained immediately before and after the procedure and 5, 10, 15, and 30 minutes later. bacteremia was demonstrable in 20 (11.4%) patients. in some, blood cultures were positive for as long as 15 minutes after barium enema; all were negative at 30 minutes. among the bacteria associated with the 20 episodes of bacteremia were escherichia coli, klebsiella, enterococci, proteus morganii, bacteroides, and veillonella. the inci ...19751093504
symbiosis of streptococcus mutans and veillonella alcalescens in mixed continuous cultures. 19751096856
bacterial studies of clindamycin-associated colitis. a preliminary report.the cause of pseudomembraneous colitis is not known but has been attributed to an alteration in the microbial flora of the colon. to test this hypothesis, a blind, prospective study was undertaken in which fecal samples were cultured quantitatively for aerobic and anaerobic organisms. the patients from which these samples were taken were all receiving clindamycin and had diarrhea secondary to the use of the drug. we were able to show definite differences in the colonic microflora which correlate ...19751097297
use of preformed cavities in rabbits for the quantitation of leukocyte chemotaxis caused by bacterial lipopolysaccharides.wound chambers implanted subcutaneously in rabbits proved suitable for measurements of leukocyte chemotaxis. injection of bacterial lipopolysaccharide (lps) in the chambers the sixth day after implantation was followed by a marked increase of polymorphonuclear leukocytes in the wound chamber fluid, the number of which was dependent on the time after application of lps. up to a certain amount of lps, the concentration of leukocytes in the chamber fluid was dose-dependent. the histopathological ap ...1976970134
use of hydroxyapatite-coasted glass beads for preclinical testing of potential antiplaque agents.methods for rapid preclinical testing of antiplaque agents in vitro using hydroxyapatite (ht)-coated glass beads are described. the assays developed could reliably detect (i) prevention of growth in the culture fluid or on the ht surfaces, (ii) the effect of transient exposure of a bactericidal agent on the viability of cells in a preformed bacterial mat, (iii) reversible adsorption of a bactericidal agent on an ht surface, and (iv) the ability of an agent to inhibit adsorption of streptococcus ...1976984818
[antibacterial and bactericidal activity of tinidazole against anaerobic bacteria comparing with metronidazole (author's transl)].antibacterial activity of tinidazole (1-2-(ethylsulfonyl)-2-methyl-5-nitroimidazole) against anaerobic bacteria including peptococcus, peptostreptococcus, eubacterium, propionibacterium, bacteroides and fusobacterium was studied by agar dilution method comparing with metronidazole. in addition to this work, bactericidal effect of tinidazole and metronidazole against p. prevotii, b. fragilis ss. fragilis and f. varium was examined by quantitative culture method after incubation in gam broth conta ...19761271586
microbial transformation of 2,4,6-trinitrotoluene and other nitroaromatic compounds.a variety of nitroaromatic compounds, including 2,4,6-trinitrotoluene (tnt), were reduced by hydrogen in the presence of enzyme preparations from veillonella alkalescens. consistent with the proposed reduction pathway, r-no2 h2 leads to r-no h2 leads to r-nhoh h2 leads to r-nh2, 3 mol of h2 was utilized per mol of nitro group. the rates of reduction of 40 mono-, di-, and trinitroaromatic compounds by v. alkalescens extract were determined. the reactivity of the nitro groups depended on other sub ...1976779650
effect of n-methyl-n'-nitro-n-nitrosoguanidine on the fecal flora of rats. 1976787606
comparison of the pyrogenicity, limulus activity mitogenicity and complement reactivity of several bacterial endotoxins and related compounds.the correlation of mitogenicity, complement activation, pyrogenicity and limulus amebocyte lysate (lal) gelation induced by 17 bacterial endotoxins (lps), modified endotoxins, related compounds, and other b cell mitogens was examined. with the use of these compounds, a significant correlation was found between pyrogenicity and mitogenicity (r = 0.85, p is less than 0.0005), pyrogenicity and lal reactivity (r = 0.84, p is less than 0.0005), and mitogenicity and lal reactivity (r = 0.72, p is less ...1976789771
the effect of dietary fiber supplementation in man. ii. alteration in fecal physiology and bacterial flora.fecal weight and water content and fecal quantitative and qualitative bacterial studies were compared on six volunteer subjects during regular diet periods and when on 5.4 g of diet fiber supplementation. there was a statistical mean stool weight increase for the group from 103 +/- 40 g to 226 +/- 90 g. the water content of the stool remained constant under the diet conditions of this study. the total anaerobic counts increased significantly while the subjects were on the high fiber diet. trend ...1976793373
deconjugation of bile acids by human intestinal bacteria.the purpose of this report is to present the deconjugation of bile acids by numbers of strains of bacteria in the small intestine and feces. the small intestinal juice was aseptically aspirated by a double lumen tube with a rubber cover on the tip devised by us ("fukushima type 1"). bile acids were analyzed with thin layer chromatography. the results: 1) among aerobic bacteria, species of which all of the strains split conjugated bile acids was enterococcus, and most of the strains split were st ...1976992250
bacteriology of the lower respiratory tract as determined by fiber-optic bronchoscopy and transtracheal aspiration.for assessment of the validity of cultures of tracheobronchial secretions and exudates (tbse) obtained by fiber-optic bronchoscopy, the aerobic and anaerobic flora of expectorated saliva and tbse obtained by fiber-optic bronchoscopy from nine healthy volunteers and eight patients were compared with those obtained by fiber-optic bronchoscopy as well). normal volunteers yielded both aerobic and anaerobic bacteria in amounts usually less than 104.5 colony-forming units (cfu)/ml in tbse obtained by ...1976993617
[empyema caused by anaerobic flora: clinical and microbiological study of 4 cases]. 1976996980
establishment of defined microbial ecosystems in germ-free rats. ii. di-association of osborne-mendel rats with veillonella alcalescens and several oral microorganisms. 19761058741
the predominant cultivable organisms in juvenile periodontitis.quantitative and qualitative examinations of the predominant cultivable microflora of the advanced tissue destruction (pocket) associated with juvenile periodontitis and of control pockets without loss of attachment were carried out by using anaerobic tube culture technique. the microflora from the control sites consisted primarily of streptococci, gram-negative rods, and gram-positive rods. in contrast, the test pockets had a relatively stable and characteristic microflora, dominated by various ...19761061986
studies on veillonellophages isolated from washings of human oral cavity. 19761072190
effect of sonic treatment on pure cultures and aggregates of bacteria.pure cultures of a variety of bacteria were treated with ultrasonic energy using a sonic probe. fractions of organisms killed at different sonic energies were calculated, and streptococcus mutans was 600 times more resistant than fusobacterium nucleatum, the most sensitive organism tested. the effects of sonic treatment on aggregates of bacteria were examined, and the results were interpreted as a model of the events that probably occur during the sonic dispersion of dental plaque.1976819454
blastogenic response of human lymphocytes to oral bacterial antigens: characterization of bacterial sonicates.soluble sonicate supernatant preparations were made from actinomyces viscosus (atcc 19246), a. naeslundii (atcc 12104), two strains of veillonella alcalescens (strain hv-1 and a human oral isolate), streptococcus sanguis (atcc 10556), s. mutans (strain 6715-t2), bacteroides melaninogenicus (strain k110), and leptotrichia buccalis (isolated from human dental plaque). these supernatants were characterized with reference to their chemical and antigenic components and their biological activity deter ...1976977126
[the microbial population of the gingival sulcus of mongoloid and normal children--a comparative study]. 1976145388
microbial succession in subgingival plaque of man. 1976133231
studies by electron-paramagnetic-resonance spectroscopy on the mechanism of action of xanthine dehydrogenase from veillonella alcalescens.e.p.r- (electron-paramagnetic-resonance) spectroscopy was used to compare chemical environment and reactivity of molybdenum, flavin and iron-sulphur centres in the enzyme xanthine dehydrogenase from veillonella alcalescens (micrococcus lactilyticus) with those of the corresponding centres in milk xanthine oxidase. the dehydrogenase is frequently contaminated with small but variable amounts of a species resistant to oxidation and giving a new molybdenum (v) e.p.r. signal, "resting i". there is al ...1976179532
acetate kinase from veillonella alcalescens. regulation of enzyme activity by succinate and substrates.acetate kinase of veillonella alcalescens has been shown to be highly regulated enzyme exhibiting two levels of control: the requirement for succinate as a heterotropic allosteric effector, and cooperative binding at the substrate level. succinate addition was necessary for enzymatic activity in both the direction of acyl phosphate synthesis and that of atp synthesis. control at the substrate level was apparent in the cooperative binding (hill coefficients of 2) of acetyl phosphate, atp, and adp ...1976178662
ph and eh in single and mixed culture bacterial plaque in an artificial mouth. 19765393
studies by electron-paramagnetic-resonance spectroscopy and stopped-flow spectrophotometry on the mechanism of action of turkey liver xanthine dehydrogenase.studies by e.p.r. (electron-paramagnetic-resonance) spectroscopy and by stopped-flow spectrophotometry on turkey liver xanthine dehydrogenase revealed strong similarities to as well as important differences from the veillonella alcalescens xanthine dehydrogenase and milk xanthine oxidase. the turkey enzyme is contaminated by up to three non-functional forms, giving molybdenum e.p.r. signals designated resting i, resting ii and slow. slow and to a lesser extent resting i signals are like those fr ...1976179533
aerobic and anaerobic flora in bladder urine of patients with indwelling urethral catheters.twenty-five bladder urine specimens from 13 patients with long-standing indwelling catheters were obtained by percutaneous suprapubic needle aspiration to avoid contamination by extraneous flora and cultured aerobically and anaerobically. twenty different species of organism were isolated from twenty-four positive specimens. the isolates were predominantly gram-negative aerobic or facultatively anaerobic bacilli, with occasional gram-positive aerobic cocci and yeasts. one patient had clostridium ...1976178084
blastogenic response of human lymphocytes to oral bacterial antigens: comparison of individuals with periodontal disease to normal and edentulous subjects.cell-mediated immunity in humans to antigens derived from oral plaque bacteria was investigated by using the lymphocyte blastogenesis assay. subjects with varying severities of periodontal disease including normal, gingivitis, periodontitis, and edentulous were compared. mononuclear leukocytes were separated from peripheral blood and cultured with antigens prepared by sonication of actinomyces viscosus (av), actinomyces naeslundii (an), veillonella alcalescens (va), leptotrichia buccalis (lb), b ...197610259
chemically defined media for growing anaerobic bacteria of the genus veillonella.a chemically defined medium for veillonella parvula and v. alcalescens is described. some nutritional aspects of the two strains used were examined: the optimum concentration of reducing agents, the requirements for amino acids, diamines, vitamins and other growth factors, and the conditions needed for well balanced nutrition. no specific requirements for single amino acids were observed. a combination of l-cysteine, dl-aspartic acid, l-glutamic acid, l-serine and l-tyrosine, promoted growth. in ...19761087858
the microbial ecology of the upper small bowel. 1976775978
effects of sodium trimetaphosphate supplementation of a high sucrose diet on the microbial and biochemical composition of four-day plaque and on urine calcium and phosphorus levels.daily supplementation of a high sucrose diet with 5 gm tmp resulted in significant alterations in certain human plaque components. veillonella and neisseria population (as percent total viable microorganisms), s sanguis (as percent streptococci), and levan hydrolase activity per milligram of plaque increased, whereas total viable microorganisms per milligram of plaque, streptococci per milligram of plaque, and specific fructosyltransferase activity decreased during the tmp-containing diet regime ...19761067293
cigarette smoking and the microbial flora of the mouth.a range of selective media was used to culture the microbial flora of the dental plaque, tongue and palate, the subjects were five young men who smoked more than twenty cigarettes a day and four who did not smoke. neisseriae were less numerous on the mucosal surfaces of the smokers.19761068665
isolation of bacteriophages specific for the genus veillonella. 19761065266
in vitro inhibition of growth of neisseria gonorrhoeae by genital microorganisms.the ability of microorganisms present in titers of over 10(5)/ml in the vaginal or cervical secretions to inhibit growth of n. gonorrhoeae in vitro was tested. study of a strain of n. gonorrhoeae against 77 microorganisms demonstrated that most strans of s. epidermidis, s. aureus and the one "gaffkya anaerobia" interfered with the growth of the n. gonorrhoeae. a minority of strains of s. viridans, neisseria, candida and bifidobacterium demonstrated interference. no strains of enterococcus, dipth ...197717163
current aspects of gas gangrene, apropos of 47 cases collected over a 3-year period (1974-1976).on the basis of 47 cases of gas gangrene collected over the three year period between 1974 and 1976, the authors review the circumstances surrounding its development, the clinical features and the prognosis of the disorder which remains grave despite a well-defined therapeutic protocol combining surgery, antibiotics and hyperbaric oxygen. there would appear to be a real resurgence of the disease at the present time. post-traumatic and surgical aetiologies predominate, giving rise to two types of ...197723023
[fecal flora of man. v. communication: the fluctuation of the fecal flora of the healthy adult (author's transl)].seven fecal specimens from each of healthy persons, aged 25 to 42 years, during the period of 2 months were analyzed to obtain the knowledge on the day-to-day variation in the same person and the person-to-person variation. irrespective of individuals, bacteroidaceae, catenabacteria (eubacteria and strict anaerobic lactobacilli), peptostreptococci (anaerobic gram positive cocci) and bifidobacteria constituted the predominant flora. spirillaceae, megasphaerae and clostridia (except cl. perfringen ...1977196456
atp formation associated with fumarate and nitrate reduction in growing cultures of veillonella alcalescens.molar growth yields, fermentation balances and enzyme activities were measured in veillonella alcalescens grown anaerobically with different substrates in the absence or presence of fumarate or nitrate. the molar growth yields on malate (14.3 g dry wt bacteria/mole substrate) and citrate (19.3) were higher than that on lactate (8.6). the molar growth yield on lactate was increased to 15.5 or 19.8 by the addition of fumarate or nitrate, respectively, to the growth medium, and the molar growth yie ...1977202192
the capacity of lipopolysaccharides from bacteroides, fusobacterium and veillonella to produce skin inflammation and the local and generalized shwartzman reaction in rabbits. 1977143518
predominant cultivable microbiota in periodontosis. 1977138729
bacteriological studies of developing supragingival dental plaque. 1977138733
leukocyte migration inhibition by bacterial antigens in patients with periodontal disease. 197712257
erythromycin and anaerobes: in vitro aspects.anaerobic organisms are being increasingly recognised as important causes of serious infection in man. sampling procedures, transport of specimens and laboratory techniques need to be constantly monitored and improved if the causative organisms are to be consistently recovered from clinical specimens. once the organisms have been isolated, their susceptibility to antibiotics should be determined so that the clinician can base his antibiotic therapy on reliable laboratory results. there are many ...1977341310
serum antibodies to plaque bacteria in subjects with dental caries and gingivitis.correlations were sought between indices of gingival inflammation and dental caries experience and serum antibody titers to five species of oral bacteria. the material comprised 53 young adult males. a statistically significant, negative correlation was observed between the antibody titer to a pool of veillonella strains and dental caries experience. multiple regression analyses failed to reveal significant associations between periodontal disease and serum antibody titers. however, the data sug ...1977320647
the predominant cultivable microflora of advanced periodontitis.a study on the predominant cultivable microorganisms harbored in the base of deep periodontal pockets of eight patients aged 34-48 years was carried out using the roll tube culture technique. from a total of 475 isolates, 425 (89.5%) were obligate anaerobes, 356(74.9%) were gram-negative, and 441(92.8%) were categorized as rods. bacteroides melaninogenicus and fusobacterium nucleatum constituted the majority of the isolates in seven samples, but their mutual proportions differed considerably bet ...1977320648
the effect of levamisole on gingival inflammation in man.the effects of levamisole on gingival inflammation and on cell-mediated immunity were examined in patients with gingivitis and in subjects with clinically healthy gingiva. treatment with levamisole promoted the development of gingivitis and aggravated the severity of established gingivitis, although the amount of bacterial plaque at the gingival margin was not significantly increased. this effect was short-lasting, as the gingival indices returned almost to base-line values by the end of the fif ...1977322263
susceptibility of various microorganisms to chlorhexidine.the susceptibility to chlorhexidine of bacteria in aerobic, facultatively anaerobic and anaerobic isolates from clinical specimens of wounds, urine, saliva, and dental plaque was studied. agar diffusion tests using 50 microng chlorhexidine discs and agar dilution tests were performed and the mic values correlated with inhibition zone diameters. anaerobic plaque strains were isolated and tested by the agar dilution method in an anaerobic glove box. regression lines obtained for five agar media de ...1977266752
lymphoproliferative response during resolution and recurrence of naturally occurring gingivitis.the lymphocyte blastogenic response in humans to oral bacterial antigens was investigated during resolution and recurrence of naturally occurring gingivitis. the following conclusions were drawn: 1. actinomyces and fusobacterium and the host responses they evoke, are associated with gingival inflammation. 2. the magnitude of the blastogenic response to these antigens is directly related to the severity of gingival inflammation. 3. scaling may cause a transient rise in the blastogenic response. 4 ...1977328846
juvenile periodontitis (periodontosis).juvenile periodontitis, characterized by early age of onset, rapid rate of periodontal tissue destruction and selective tooth involvement in the absence of commensurate aetiological factors, is recognized as a distinct clinical entity. the present paper describes the clinical findings and some immunological characteristics in a group of thirty-four patients under the age of thirty. clinical aspects studied included the influence of sex, race, family history and general health. immunological find ...1977267621
effect of fissure sealing on the microflora in occlusal fissures of human teeth. 1977270316
microorganisms in recurrent aphthous ulcerations.qualitative and quantitative examinations of the cultivable bacterial flora in biopsies from recurrent aphthous ulcerations (rau), experimental oral ulcerations (eou), and normal oral mucosa (nom) were carried out under aerobic and continuous anaerobic conditions. an attempt was made to culture yeasts, mycoplasma, and virus from the biopsies of rau, which were also tested for the presence of herpes virus antigen by the fluorescent antibody method. the predominant bacteria recovered in rau were a ...1977271340
[nitrate reduction in human saliva. 3. nitrate reduction in veillonella (author's transl)]. 1977287541
susceptibility to erythromycin of anaerobes of the genera bacteroides, fusobacterium, sphaerophorus, veillonella, clostridium, corynebacterium, peptococcus, peptostreptococcus.the minimal inhibitory concentrations (mic) of erythromycin were determined by broth dilution tests for 313 anaerobic strains, most of which were clinical isolates. all the gram-positive anaerobes tested (84 peptococcaceae, including 21 peptostreptococcus anaerobius and 15 peptococcus variabilis; 65 corynebacterium acnes and 29 clostridium strains, including 13 c. perfringens) were sensitive (mic values 0.012 through 3.12 microgram erythromycin/ml); so were 111 cultures of gram-negative anaerobe ...1977580038
in vitro sensitivity of anaerobic bacteria to fosfomycin.the minimum inhibitory concentrations were determined in 98 strains of anaerobic bacteria that came from clinical samples against fosfomycin, penicillin, cephalothin, tetracycline, chloramphenicol, clindamycin and lincomycin. the results obtained indicate that fosfomycin is usually inactive against bacteroides sp. and is active up to 32 mug/ml or less against 85% of peptococcus and 95% of peptostreptococcus, being consequently comparatively less active than the rest of the antibiotics that were ...1977583867
nitrate-reductase electron-transport cofactors in veillonella alcalescens.studies on the effects of inhibitors of the nitrate-reducing activity of veillonella alcalescens extracts suggest the participation of a naphthoquinone, a b-type cytochrome, and non-heme iron in electron transport to nitrate. a nitrate-reductase-deficient mutant displayed a longer doubling time and a decreased molar growth yield on nitrate media. this mutant was phenotypically restored by the addition of molybdate to the growth medium, giving evidence for the functioning of molybdenum in the nit ...1977922606
interdependence of in vitro responsiveness of cord and maternal blood lymphocytes to antigens from oral bacteria.a group of thirty-five mothers and their babies at parturition were examined by the in vitro lymphocyte transformation test to determine sensitization by oral bacterial antigens, b-cell mitogens and dental plaque. lymphocytes from babies of sensitized mothers with gingival or periodontal disease gave the highest frequency (70 and 63%) and magnitude (mean stimulation index of 3.4 and 3.3) of response in cultures stimulated by actinomyces viscosus and veillonella alcalescens. however, igm antibodi ...1977606445
effect of bacterial products on inflammatory reactions in the dental pulp.culture filtrates (extracellular components) and material obtained from disintegrated cells (intracellular components) of cultured plaque bacteria were studied for their capacity to induce inflammatory reactions in the dental pulp. class v cavities were prepared on the buccal surface of 94 teeth: 42 test and 52 control teeth in six adult monkeys. lyophilized bacterial components were sealed into the test cavities either alone or following an 8-h topical application of a solution of the same comp ...1977402688
bacteremia after upper gastrointestinal endoscopy.during 24 months, 200 upper gastrointestinal endoscopies were performed on 193 patients. blood cultures were obtained before and five and 30 minutes after the procedure using thiol (50 ml) and trypticase soy broth (100 ml) media. the mean endoscopic time was 34 minutes. sixteen patients developed bacteremia (8%). twelve groups of microorganisms were detected in positive blood cultures: streptococcus (5 species), lactobacillus sp, veillonella alcalescens, staphylococcus aureus, staph epidermidis, ...1977404974
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