Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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| using next-generation sequencing approaches to isolate simple sequence repeat (ssr) loci in the plant sciences. | the application of next-generation sequencing (ngs) technologies for the development of simple sequence repeat (ssr) or microsatellite loci for genetic research in the botanical sciences is described. microsatellite markers are one of the most informative and versatile dna-based markers used in plant genetic research, but their development has traditionally been a difficult and costly process. ngs technologies allow the efficient identification of large numbers of microsatellites at a fraction o ... | 2012 | 22186186 |
| effects of cranberry extracts on growth and biofilm production of escherichia coli and staphylococcus species. | biofilm producing bacteria such as staphylococcus species and escherichia coli are the most common cause of catheter related urinary tract infections (utis). the american cranberry (vaccinium macrocarpon) is utilized widely as a prophylaxis for utis due to its prevention of microbial adhesion. cranberry contains proanthocyanidins (pacs), which have been implicated as active constituents responsible for its bacterial antiadhesive properties. despite overwhelming data supporting cranberry's benefi ... | 2012 | 22294419 |
| comparisons of large (vaccinium macrocarpon ait.) and small (vaccinium oxycoccos l., vaccinium vitis-idaea l.) cranberry in british columbia by phytochemical determination, antioxidant potential, and metabolomic profiling with chemometric analysis. | there is a long history of use and modern commercial importance of large and small cranberries in north america. the central objective of the current research was to characterize and compare the chemical composition of 2 west coast small cranberry species traditionally used (vaccinium oxycoccos l. and vaccinium vitis-idaea l.) with the commercially cultivated large cranberry (vaccinium macrocarpon ait.) indigenous to the east coast of north america. v. oxycoccos and v. macrocarpon contained the ... | 2012 | 22337317 |
| american cranberry (vaccinium macrocarpon) extract affects human prostate cancer cell growth via cell cycle arrest by modulating expression of cell cycle regulators. | prostate cancer is one of the most common cancers in the world, and its prevalence is expected to increase appreciably in the coming decades. as such, more research is necessary to understand the etiology, progression and possible preventative measures to delay or to stop the development of this disease. recently, there has been interest in examining the effects of whole extracts from commonly harvested crops on the behaviour and progression of cancer. here, we describe the effects of whole cran ... | 2012 | 22388548 |
| the antimicrobial effects of cranberry against staphylococcus aureus. | the antimicrobial effects of the american cranberry (vaccinium macrocarpon) on a major food-borne pathogen, staphylococcus aureus, were investigated using commercially obtained lakewood® organic cranberry juice and ocean spray® cranberry juice cocktail and four other berry fruit extracts (acai berry, strawberry, raspberry, and blueberry). the results showed that cranberry is a potent antimicrobial against s. aureus and the most potent among the berries studied. the order of percentage inhibition ... | 2012 | 22414934 |
| comprehensive assessment of the quality of commercial cranberry products. phenolic characterization and in vitro bioactivity. | cranberry (vaccinium macrocarpon) products have been widely recommended in traditional american medicine for the treatment of urinary tract infection (uti). a total of 19 different commercial cranberry products from american and european markets have been analyzed by different global phenolic methods and by uplc-dad-esi-tq ms. in addition, in vitro antioxidant capacity and uropathogenic bacterial antiadhesion activity tests have been performed. results revealed that products found in the market ... | 2012 | 22439747 |
| investigation on the protective effects of cranberry against the dna damage induced by benzo[a]pyrene. | there are few reports that demonstrate the antigenotoxic potential of cranberries. although the types of berry fruits consumed worldwide are many, this paper focuses on cranberries that are commonly consumed in mexico (vaccinium macrocarpon species). the purpose of the present study is to determine whether cranberry ethanolic extract (cee) can prevent the dna damage produced by benzo[a]pyrene (b[a]p) using an in vivo mouse peripheral blood micronucleus assay. the experimental groups were organiz ... | 2012 | 22499190 |
| an innovative approach to the safety evaluation of natural products: cranberry (vaccinium macrocarpon aiton) leaf aqueous extract as a case study. | assessment of safety for a food or dietary ingredient requires determination of a safe level of ingestion compared to the estimated daily intake from its proposed uses. the nature of the assessment may require the use of different approaches, determined on a case-by-case basis. natural products are chemically complex and challenging to characterize for the purpose of carrying out a safety evaluation. for example, a botanical extract contains numerous compounds, many of which vary across batches ... | 2012 | 22504784 |
| comparison of isolated cranberry (vaccinium macrocarpon ait.) proanthocyanidins to catechin and procyanidins a2 and b2 for use as standards in the 4-(dimethylamino)cinnamaldehyde assay. | the 4-(dimethylamino)cinnamaldehyde (dmac) assay is currently used to quantify proanthocyanidin (pac) content in cranberry products. however, this method suffers from issues of accuracy and precision in the analysis and comparison of pac levels across a broad range of cranberry products. current use of procyanidin a2 as a standard leads to an underestimation of pacs content in certain cranberry products, especially those containing higher molecular weight pacs. to begin to address the issue of a ... | 2012 | 22533362 |
| phenotyping studies to assess the effects of phytopharmaceuticals on in vivo activity of main human cytochrome p450 enzymes. | the extensive use of herbal drugs and their multiple components and modes of action suggests that they may also cause drug interactions by changing the activity of human cytochrome p450 enzymes. the purpose of the present review is to present the available data for the top 14 herbal drug sales in the u. s. studies describing the effects of herbal drugs on phenotyping substrates for individual cyps were identified by a comprehensive medline search. drugs included allium sativum (liliaceae), echin ... | 2012 | 22588833 |
| functionality of varroa-resistant honey bees (hymenoptera: apidae) when used in migratory beekeeping for crop pollination. | two types of honey bees, apis mellifera l. (hymenoptera: apidae), bred for resistance to varroa destructor anderson & trueman were evaluated for performance when used in migratory crop pollination. colonies of russian honey bees (rhb) and outcrossed bees with varroa-sensitive hygiene (vsh) were managed without miticide treatments and compared with colonies of italian honey bees that served as controls. control colonies were managed as groups which either were treated twice each year against v. d ... | 2012 | 22606798 |
| composition of sugars, organic acids, and total phenolics in 25 wild or cultivated berry species. | sugars, organic acids, and total phenolic content in fruit of 25 wild and cultivated berry species were identified and quantified with high-performance liquid chromatograph. the composition of sugars, organic acids, and total phenolic compounds in various species of vaccinium, rubus, ribes, and fragaria genus was evaluated. additonally, total phenolics of less known berry species of the morus, amelanchier, sorbus, sambucus, rosa, lycium, actinidia, and aronia genus were determined in wild growin ... | 2012 | 22924969 |
| phenology of dasineura oxycoccana (diptera: cecidomyiidae) on cranberry and blueberry indicates potential for gene flow. | dasineura oxycoccana (johnson) (diptera: cecidomyiidae) is a pest of cranberry, vaccinium macrocarpon (aiton) (ericales: ericaceae), and highbush blueberry, vaccinium corymbosum (l.) (ericales: ericaceae), in north america. in british columbia, canada, d. oxycoccana was first found on highbush blueberry in 1991 and then on cranberry seven years later. because many cranberry and highbush blueberry farms are adjacent to one another, we hypothesized that d. oxycoccana was moving from highbush blueb ... | 2012 | 22928299 |
| injury to apical meristem of cranberry by dasineura oxycoccana (diptera: cecidomyiidae) reduces production of floral-units in the next growing season. | cranberry tipworm, dasineura oxycoccana johnson (a gall-making fly), disrupts normal growth of cranberry (vaccinium macrocarpon aiton) by injuring the apical meristem of shoots or uprights. the impact of larval feeding injury on reproductive parameters of cranberry was determined, from one growing season to next, at upright (maine and massachusetts, 2008-2009) and plot levels (massachusetts, 2009-2010 and 2010-2011). we also estimated the proportions of uprights injured because of tipworm feedin ... | 2012 | 22928318 |
| comparing procyanidins in selected vaccinium species by uhplc-ms(2) with regard to authenticity and health effects. | cranberry procyanidins have been associated with an effect against urinary tract infections (uti) for decades, and european health claims are requested. this study compares the procyanidin profiles and concentrations of american cranberry ( vaccinium macrocarpon ait.), european cranberry ( vaccinium oxycoccus l.), and lingonberry ( vaccinium vitis-idaea l.) analyzed using ultrahigh-performance liquid chromatoraphy coupled to a triple-quadrupole mass spectrometer with electrospray interface (uhpl ... | 2012 | 22931094 |
| deconvolution of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry isotope patterns to determine ratios of a-type to b-type interflavan bonds in cranberry proanthocyanidins. | a method to deconvolute overlapping isotope patterns in positive mode matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof ms) was developed to determine ratios of a- to b-type interflavan bonds in proanthocyanidins that were isolated from cranberry (vaccinium macrocarpon, ait.) press cake (c-pac). precision and accuracy was validated for binary mixtures of procyanidins a2 and b2. deconvolution of c-pac spectra indicated that oligomers with one or more a-type i ... | 2012 | 22953884 |
| enteric-coated, highly standardized cranberry extract reduces risk of utis and urinary symptoms during radiotherapy for prostate carcinoma. | cranberry (vaccinium macrocarpon) proanthocyanidins can interfere with adhesion of bacteria to uroepithelial cells, potentially preventing lower urinary tract infections (lutis). because lutis are a common side effect of external beam radiotherapy (ebrt) for prostate cancer, we evaluated the clinical efficacy of enteric-coated tablets containing highly standardized v. msacrocarpon (ecvm) in this condition. | 2012 | 22977312 |
| hplc-msn identification and quantification of flavonol glycosides in 28 wild and cultivated berry species. | berries and red fruits are rich dietary sources of polyphenols with reported health benefits. more than 50 different flavonols (glycosides of quercetin, myricetin, kaempferol, isorhamnetin, syringetin and laricitrin) have been detected and quantified with hplc-ms(n) in fruits of blueberry, bilberry, cranberry, lingonberry, eastern shadbush, japanese wineberry, black mulberry, chokeberry, red, black and white currants, jostaberry, red and white gooseberry, hardy kiwifruit, goji berry, rowan, dog ... | 2012 | 22980782 |
| chromobacterium vaccinii sp. nov., isolated from native and cultivated cranberry (vaccinium macrocarpon ait.) bogs and irrigation ponds. | a large number of gram-negative, motile, mesophilic, violacein-producing bacteria were isolated from the soils and roots of vaccinium macrocarpon ait. and kalmia angustifolia l. plants and from irrigation ponds associated with wild and cultivated cranberry bogs in massachusetts, usa. phylogenetic analyses of 16s rrna gene sequences placed these isolates in a clade with chromobacterium species, but the specialized environment from which they were isolated, their low genomic dna relatedness with c ... | 2013 | 22984138 |
| effects of cranberry components on human aggressive periodontitis gingival fibroblasts. | aggressive periodontitis (agp) causes rapid periodontal breakdown involving agp gingival fibroblast production of cytokines [i.e. interleukin (il)-6, a bone metabolism regulator], and matrix metalloproteinase (mmp)-3. lipopolysaccharide upregulates fibroblast il-6 and mmp-3, via transcription factors (i.e. nf-κb). cranberry (vaccinium macrocarpon) inhibits lipopolysaccharide-stimulated macrophage and normal gingival fibroblast activities, but little is known of its effects on agp fibroblasts. ob ... | 2013 | 23106206 |
| micropropagation of vaccinium sp. by in vitro axillary shoot proliferation. | the vaccinium genus contains several valuable fruit and ornamental species, among others: highbush blueberry (vaccinium × corymbosum l.), cranberry (vaccinium macrocarpon ait.), and lingonberry (vaccinium vitis-idaea l.). in some most popular and valuable cultivars, the conventional propagation methods, exploiting hard or soft wood cuttings, are inefficient. the demand for nursery plants could be fulfilled only by micropropagation. in principle cultivars are propagated in vitro through similar t ... | 2013 | 23179690 |
| the first genetic map of the american cranberry: exploration of synteny conservation and quantitative trait loci. | the first genetic map of cranberry (vaccinium macrocarpon) has been constructed, comprising 14 linkage groups totaling 879.9 cm with an estimated coverage of 82.2 %. this map, based on four mapping populations segregating for field fruit-rot resistance, contains 136 distinct loci. mapped markers include blueberry-derived simple sequence repeat (ssr) and cranberry-derived sequence-characterized amplified region markers previously used for fingerprinting cranberry cultivars. in addition, ssr marke ... | 2013 | 23224333 |
| populations of the gall midge dasineura oxycoccana on cranberry and blueberry produce and respond to different sex pheromones. | we identified and field-tested the sex pheromones of dasineura oxycoccana (johnson) (diptera: cecidomyiidae) midges collected from cranberry, vaccinium macrocarpon aiton, and from highbush blueberry, vaccinium corymbosum l., commonly named cranberry tipworm (ctw) and blueberry gall midge (bgm), respectively. coupled gas chromatographic-electroantennographic detection (gc-ead) analyses of pheromone gland extract from the ovipositor of calling ctw females revealed one component (<10 pg per oviposi ... | 2013 | 23297107 |
| identification of polyphenols and their metabolites in human urine after cranberry-syrup consumption. | as the beneficial effects of american cranberry (vaccinium macrocarpon) can be partly attributed to its phenolic composition, the evaluation of the physiological behaviour of this fraction is crucial. a rapid and sensitive method by ultra-performance liquid chromatography coupled to quadrupole-time-of-flight mass spectrometry (uplc-q-tof-ms) has been used to identify phenolic metabolites in human urine after a single dose of cranberry syrup. prior to the analysis, metabolites were extracted usin ... | 2013 | 23395719 |
| quantifying and characterizing proanthocyanidins in cranberries in relation to urinary tract health. | the "a-type" proanthocyanidins in cranberry fruit (vaccinium macrocarpon ait.) are bioactive components associated with prevention of urinary tract infections (uti). cranberry juice, fruit (fresh and dried), functional foods, and cranberry dietary supplements are promoted for prevention of uti and for maintenance of urinary tract health (uth), on the basis of their content of cranberry proanthocyanidins (c-pac) with "a-type" interflavan bonds. with increasing consumer use of cranberries for main ... | 2013 | 23397091 |
| quantification by uhplc of total individual polyphenols in fruit juices. | the present work proposes a new uhplc-pda-fluorescence method able to identify and quantify the main polyphenols present in commercial fruit juices in a 28-min chromatogram. the proposed method improve the ifu method no. 71 used to evaluate anthocyanins profiles of fruit juices. fruit juices of strawberry, american cranberry, bilberry, sour cherry, black grape, orange, and apple, were analysed identifying 70 of their main polyphenols (23 anthocyanins, 15 flavonols, 6 hydroxybenzoic acids, 14 hyd ... | 2013 | 23411199 |
| effect of ph on anti-rotavirus activity by comestible juices and proanthocyanidins in a cell-free assay system. | cranberry (vaccinium macrocarpon) and grape (vitis labrusca) juices, and these species' secondary plant metabolites [i.e., proanthocyanidins (pacs)] possess antiviral activity. an understanding of the mechanism(s) responsible for these juices and their polyphenolic constituents' direct effect on enteric virus integrity, however, remains poorly defined. using the rotavirus (rtv) as a model enteric virus system, the direct effect of manufacturer-supplied and commercially purchased juices [ocean sp ... | 2012 | 23412889 |
| inhibition of interleukin-17-stimulated interleukin-6 and -8 production by cranberry components in human gingival fibroblasts and epithelial cells. | gingival epithelial cells and fibroblasts participate in periodontal inflammation and destruction, producing interleukin (il)-6, a regulator of osteoclastic bone resorption, and the neutrophil chemoattractant il-8. il-17, a product of t-helper 17 cells, may play a role in periodontitis by stimulating cytokine production by gingival cells. the cranberry (vaccinium macrocarpon) is rich in polyphenols, particularly proanthocyanidins, which have antioxidant and other beneficial properties. cranberry ... | 2013 | 23441749 |
| the effect of american cranberry (vaccinium macrocarpon) constituents on the growth inhibition, membrane integrity, and injury of escherichia coli o157:h7 and listeria monocytogenes in comparison to lactobacillus rhamnosus. | the antimicrobial properties of the american cranberry were studied against escherichia coli o157:h7, listeria monocytogenes, and lactobacillus rhamnosus to determine the effects on growth inhibition, membrane permeability, and injury. cranberry powder was separated using a c-18 sep-pak cartridge into sugars plus organic acids (f1), monomeric phenolics (f2), and anthocyanins plus proanthocyanidins (f3). fraction 3 was further separated into anthocyanins (f4) and proanthocyanidins (f5) using an l ... | 2013 | 23541202 |
| high performance thin layer chromatography-densitometry: a step further for quality control of cranberry extracts. | a method for selective quantitation of catechin, proanthocyanidin (pac) a2 and pac-b1 in american cranberry (vaccinium macrocarpon) extracts using high performance thin layer chromatography (hptlc)-densitometry is presented. methylene chloride/ethyl acetate/formic acid (6:10:1, v/v) as the mobile phase and 1% vanillin hydrochloric solution as staining reagent were used. in these conditions, three standards considered as quality markers, catechin, pac-a2 and pac-b1, were well resolved allowing si ... | 2013 | 23561183 |
| jasmonate-mediated induced volatiles in the american cranberry, vaccinium macrocarpon: from gene expression to organismal interactions. | jasmonates, i.e., jasmonic acid (ja) and methyl jasmonate (meja), are signaling hormones that regulate a large number of defense responses in plants which in turn affect the plants' interactions with herbivores and their natural enemies. here, we investigated the effect of jasmonates on the emission of volatiles in the american cranberry, vaccinium macrocarpon, at different levels of biological organization from gene expression to organismal interactions. at the molecular level, four genes (bcs, ... | 2013 | 23641249 |
| habitat and host indicate lineage identity in colletotrichum gloeosporioides s.l. from wild and agricultural landscapes in north america. | understanding the factors that drive the evolution of pathogenic fungi is central to revealing the mechanisms of virulence and host preference, as well as developing effective disease control measures. prerequisite to these pursuits is the accurate delimitation of species boundaries. colletotrichum gloeosporioides s.l. is a species complex of plant pathogens and endophytic fungi for which reliable species recognition has only recently become possible through a multi-locus phylogenetic approach. ... | 2013 | 23671594 |
| cysticlean® a highly pac standardized content in the prevention of recurrent urinary tract infections: an observational, prospective cohort study. | the present study was aimed at determining the prophylactic efficacy of american cranberry (ac) extract (cysticlean®) in women with recurrent symptomatic postcoital urinary tract infections (pcuti), non-consumer of ac extract in the past 3 months before inclusion, and to determine changes in their quality of life (qol). | 2013 | 23738867 |
| cranberry impairs selected behaviors essential for virulence in proteus mirabilis hi4320. | proteus mirabilis is an etiological agent of complicated urinary tract infections. north american cranberries (vaccinium macrocarpon) have long been considered to have protective properties against urinary tract infections. this work reports the effects of cranberry powder (cp) on the motility of p. mirabilis hi4320 and its expression of flaa, flhd, and ured. our results show that swimming and swarming motilities and swarmer-cell differentiation were inhibited by cp. additionally, transcription ... | 2013 | 23750959 |
| impact of early season apical meristem injury by gall inducing tipworm (diptera: cecidomyiidae) on reproductive and vegetative growth of cranberry. | larvae of cranberry tipworm, dasineura oxycoccana johnson, disrupt early season growth of cranberry (vaccinium macrocarpon aiton) uprights or shoots by feeding on apical meristem tissue. a 2-yr field study was carried out at three different locations to determine the impact of tipworm feeding injury on the reproductive and vegetative growth of two cranberry cultivars ('howes' and 'stevens') in massachusetts. in addition to tipworm-injured and intact control uprights, an artificial injury treatme ... | 2013 | 23865200 |
| prevention of urinary tract infections with vaccinium products. | cranberries exert a dose-dependent inhibition of the adherence of e. coli fimbriae to uroepithelial cells. this was demonstrated in vitro but also ex vivo in vitro with urine from cranberry consumers. the active principle has not been identified in detail but type-a proanthocyanidins (pac) play an important role in the mechanism of action. since the three species, american cranberry (vaccinium macrocarpon), european cranberry (vaccinium oxycoccus) and/or lingonberry (vaccinium vitis-idaea), have ... | 2014 | 23922238 |
| development and validation of a sensitive, high-throughput bioassay for the adhesion of radiolabeled e. coli to uroepithelial cells in vitro. | vaccinium macrocarpon (cranberry) products have been used to prevent uropathogenic escherichia (e.) coli adherence to uroepithelial cells (uec) and may help reduce risk of urinary tract infection. reported herein are the development and validation of an assay to assess antiadhesion activity of v. macrocarpon extracts and human urine. p-fimbriated e. coli (cft073) was labeled with ³h-uridine, then co-incubated with htb-4 uec at a 400:1 ratio. v. macrocarpon extracts (0-17 mg proanthocyanidins/ml) ... | 2013 | 23964569 |
| cranberry flowering times and climate change in southern massachusetts. | plants in wild and agricultural settings are being affected by the warmer temperatures associated with climate change. here we examine the degree to which the iconic new england cranberry, vaccinium macrocarpon, is exhibiting signs of altered flowering phenology. using contemporary records from commercial cranberry bogs in southeastern massachusetts in the united states, we found that cranberry plants are responsive to temperature. flowering is approximately 2 days earlier for each 1 °c increase ... | 2014 | 24018848 |
| cranberry-derived proanthocyanidins prevent formation of candida albicans biofilms in artificial urine through biofilm- and adherence-specific mechanisms. | candida albicans is a common cause of nosocomial urinary tract infections (utis) and is responsible for increased morbidity and healthcare costs. moreover, the us centers for medicare & medicaid services no longer reimburse for hospital-acquired catheter-associated utis. thus, development of specific approaches for the prevention of candida urinary infections is needed. cranberry juice-derived proanthocyanidins (pacs) have efficacy in the prevention of bacterial utis, partially due to anti-adher ... | 2014 | 24114570 |
| phytochemicals in fruits of hawaiian wild cranberry relatives. | cranberries (vaccinium macrocarpon ait.) contain high levels of phytochemicals such as proanthocyanidins (pacs). these polymeric condensations of flavan-3-ol monomers are associated with health benefits. our objective was to evaluate phytochemicals in fruit from hawaiian cranberry relatives, v. reticulatum sm. and v. calycinum sm. normal-phase hplc coupled with fluorescence and esi-ms detected pacs; the colorimetric 4-dimethylaminocinnamaldehyde (dmac) assay was used to determine total pacs. spe ... | 2014 | 24154960 |
| rapds identify varietal misclassification and regional divergence in cranberry [vaccinium macrocarpon (ait.) pursh]. | the majority of cultivated cranberry varieties were selected from native populations in the 1800s and early 1900s from sites in massachusetts, new jersey, and wisconsin. since their initial selections 100-150 years ago, varietal identities have become increasingly confused; primarily the result of there being a paucity of qualitative markers to effectively distinguish among varieties. random amplified polymorphic dna (rapd) technology has the potential for allowing a more definitive classificati ... | 1994 | 24186254 |
| the american cranberry mitochondrial genome reveals the presence of selenocysteine (trna-sec and secis) insertion machinery in land plants. | this is the first de novo assembly and annotation of a complete mitochondrial genome in the ericales order from the american cranberry (vaccinium macrocarpon ait.). moreover, only four complete asterid mitochondrial genomes have been made publicly available. the cranberry mitochondrial genome was assembled and reconstructed from whole genome 454 roche gs-flx and illumina shotgun sequences. compared with other asterids, the reconstruction of the genome revealed an average size mitochondrion (459, ... | 2014 | 24342657 |
| cranberry versus placebo in the prevention of urinary infections in multiple sclerosis: a multicenter, randomized, placebo-controlled, double-blind trial. | our aim was to assess the usefulness of cranberry extract in multiple sclerosis (ms) patients suffering from urinary disorders. | 2014 | 24402038 |
| in vitro studies on the relationship between the antioxidant activities of some berry extracts and their binding properties to serum albumin. | the aim of this study was to investigate the possibility to use the bioactive components from cape gooseberry (physalis peruviana), blueberry (vaccinium corymbosum), and cranberry (vaccinium macrocarpon) extracts as a novel source against oxidation in food supplementation. the quantitative analysis of bioactive compounds (polyphenols, flavonoids, flavanols, carotenoids, and chlorophyll) was based on radical scavenging spectrophometric assays and mass spectrometry. the total phenolic content was ... | 2014 | 24449373 |
| variation in proanthocyanidin content and composition among commonly grown north american cranberry cultivars (vaccinium macrocarpon). | cranberry fruit (vaccinium macrocarpon) is rich in polyphenols, particularly oligomeric proanthocyanidins (pacs) possessing antimicrobial and antioxidant properties. pacs may play a role in resistance to fruit rot. although many cranberry cultivars are grown for use in foods, beverages and nutraceuticals, data on pac content among cultivars is limited. eight cultivars were sampled from four growing regions during the 2010 season and analyzed for pac content and composition. | 2014 | 24532348 |
| promising results of cranberry in the prevention of oral candida biofilms. | in the context of dental caries prevention by natural foodstuff sources, antifungal and antibiofilm activities of dry commercial extracts of cranberry fruit (vaccinium macrocarpon aiton) and two other red fruits (vaccinium myrtillus l. and malpighia punicifolia l.) were assessed on candida albicans and candida glabrata yeasts. when added to the culture medium, the cranberry extract displayed a significant anti-adhesion activity against candida spp. when used at low concentrations. in addition, t ... | 2014 | 24623607 |
| anthocyanin incorporated dental copolymer: bacterial growth inhibition, mechanical properties, and compound release rates and stability by (1)h nmr. | objective. to evaluate bacterial growth inhibition, mechanical properties, and compound release rate and stability of copolymers incorporated with anthocyanin (acy; vaccinium macrocarpon). methods. resin samples were prepared (bis-gma/tegdma at 70/30 mol%) and incorporated with 2 w/w% of either acy or chlorhexidine (chx), except for the control group. samples were individually immersed in a bacterial culture (streptococcus mutans) for 24 h. cell viability (n = 3) was assessed by counting the num ... | 2014 | 24693287 |
| diversity of fungi associated with hair roots of ericaceous plants is affected by land use. | culture-independent molecular studies have provided new insights into the diversity of fungi associating with ericaceous plant roots. however, there is little understanding of the distribution of these fungi across landscapes, or the effects of environmental heterogeneity on ericoid mycorrhizal (erm) fungal diversity and distribution. terminal-restriction fragment length polymorphism and selective sequence analyses of the internal transcribed spacer regions of rdna were used to infer fungal dive ... | 2014 | 24741702 |
| development of a fluorometric microplate antiadhesion assay using uropathogenic escherichia coli and human uroepithelial cells. | a fluorometric microplate assay has been developed to determine escherichia (e.) coli adhesion to uroepithelial cells (uec). p-fimbriated e. coli were labeled with baclight green and preincubated 30 min with human urine or standard. fluorescent-e. coli were added to uec in mircoplates at a 400:1 ratio, incubated 1 h, and washed, and the fluorescence intensity was measured. specific labeling and adherence were confirmed by flow cytometry. a myricetin (1) standard curve (0-30 μg/ml) was developed; ... | 2014 | 24749980 |
| consumption of cranberry beverage improved endogenous antioxidant status and protected against bacteria adhesion in healthy humans: a randomized controlled trial. | consumption of polyphenol-rich foods is associated with lower risk from many chronic diseases. we hypothesized that a single dose of cranberry beverage would improve indices of oxidative stress, inflammation, and urinary antibacterial adhesion activity in healthy humans. six males and 6 females (18-35 years; body mass index, 19-25 kg/m(2)) consumed placebo, cranberry leaf extract beverage, or low-calorie cranberry juice cocktail (lcjc) once in a randomized, double-blind, placebo-controlled cross ... | 2014 | 24916555 |
| the american cranberry: first insights into the whole genome of a species adapted to bog habitat. | the american cranberry (vaccinium macrocarpon ait.) is one of only three widely-cultivated fruit crops native to north america- the other two are blueberry (vaccinium spp.) and native grape (vitis spp.). in terms of taxonomy, cranberries are in the core ericales, an order for which genome sequence data are currently lacking. in addition, cranberries produce a host of important polyphenolic secondary compounds, some of which are beneficial to human health. whereas next-generation sequencing techn ... | 2014 | 24927653 |
| distinguishing vaccinium species by chemical fingerprinting based on nmr spectra, validated with spectra collected in different laboratories. | a method was developed to distinguish vaccinium species based on leaf extracts using nuclear magnetic resonance spectroscopy. reference spectra were measured on leaf extracts from several species, including lowbush blueberry (vaccinium angustifolium), oval leaf huckleberry (vaccinium ovalifolium), and cranberry (vaccinium macrocarpon). using principal component analysis, these leaf extracts were resolved in the scores plot. analysis of variance statistical tests demonstrated that the three group ... | 2014 | 24963620 |
| a polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased akkermansia spp. population in the gut microbiota of mice. | the increasing prevalence of obesity and type 2 diabetes (t2d) demonstrates the failure of conventional treatments to curb these diseases. the gut microbiota has been put forward as a key player in the pathophysiology of diet-induced t2d. importantly, cranberry (vaccinium macrocarpon aiton) is associated with a number of beneficial health effects. we aimed to investigate the metabolic impact of a cranberry extract (ce) on high fat/high sucrose (hfhs)-fed mice and to determine whether its consequ ... | 2015 | 25080446 |
| flavonoids and phenolic acids from cranberry juice are bioavailable and bioactive in healthy older adults. | cranberries (vaccinium macrocarpon) are a rich source of phenolic phytochemicals, which likely contribute to their putative health benefits. a single-dose pharmacokinetic trial was conducted in 10 healthy adults ⩾50y to evaluate the acute (24-h) absorption and excretion of flavonoids, phenolic acids and proanthocyanidins (pacs) from a low-calorie cranberry juice cocktail (54% juice). inter-individual variability was observed in the cmax and tmax of many of these compounds in both plasma and urin ... | 2015 | 25172705 |
| american cranberry (proanthocyanidin 120 mg): its value for the prevention of urinary tracts infections after ureteral catheter placement. | urinary tract infection (uti) is among the most frequent complications after urinary tract surgical procedures, mainly when catheter placement is necessary. although the use of american cranberry has been related with a reduced risk of uti, there is no study reporting the value of its prevention effect against catheter-associated urinary tract infections. | 2015 | 25204992 |
| effect of standardized cranberry extract on the activity and expression of selected biotransformation enzymes in rat liver and intestine. | the use of dietary supplements containing cranberry extract is a common way to prevent urinary tract infections. as consumption of these supplements containing a mixture of concentrated anthocyanins and proanthocyanidins has increased, interest in their possible interactions with drug-metabolizing enzymes has grown. in this in vivo study, rats were treated with a standardized cranberry extract (cysticran®) obtained from vaccinium macrocarpon in two dosage schemes (14 days, 0.5 mg of proanthocyan ... | 2014 | 25237750 |
| development and validation of 697 novel polymorphic genomic and est-ssr markers in the american cranberry (vaccinium macrocarpon ait.). | the american cranberry, vaccinium macrocarpon ait., is an economically important north american fruit crop that is consumed because of its unique flavor and potential health benefits. however, a lack of abundant, genome-wide molecular markers has limited the adoption of modern molecular assisted selection approaches in cranberry breeding programs. to increase the number of available markers in the species, this study identified, tested, and validated microsatellite markers from existing nuclear ... | 2015 | 25633331 |
| metabolomics for phytochemical discovery: development of statistical approaches using a cranberry model system. | metabolomics is the qualitative and quantitative analysis of all of the small molecules in a biological sample at a specific time and influence. technologies for metabolomics analysis have developed rapidly as new analytical tools for chemical separations, mass spectrometry, and nmr spectroscopy have emerged. plants have one of the largest metabolomes, and it is estimated that the average plant leaf can contain upward of 30 000 phytochemicals. in the past decade, over 1200 papers on plant metabo ... | 2015 | 25751407 |
| characterization of in vitro antifungal activities of small and american cranberry (vaccinium oxycoccos l. and v. macrocarpon aiton) and lingonberry (vaccinium vitis-idaea l.) concentrates in sugar reduced fruit spreads. | in this study, cranberry and lingonberry concentrates were added to commercial sugar-reduced fruit spreads (raspberry-aloe vera, strawberry-guava, and strawberry-lime), and tested for their antifungal activities. selected strains of the species absidia glauca, penicillium brevicompactum, saccharomyces cerevisiae and zygosaccharomyces bailii, as well as xerophilic environmental isolates of the genera penicillium and eurotium were used for challenge testing. initially, varying concentrations of sy ... | 2015 | 25868124 |
| adhesion of asaia bogorensis to glass and polystyrene in the presence of cranberry juice. | the aim of the study was to evaluate the adhesion abilities of the acetic acid bacterium asaia bogorensis to glass and polystyrene in the presence of american cranberry (vaccinium macrocarpon) juice. the strain of a. bogorensis used was isolated from spoiled commercial fruit-flavored drinking water. the cranberry juice was analyzed for polyphenols, organic acids, and carbohydrates using high-performance liquid chromatography and liquid chromatography-mass spectrometry techniques. the adhesive ab ... | 2015 | 26038911 |
| cranberry fruit powder (flowens™) improves lower urinary tract symptoms in men: a double-blind, randomized, placebo-controlled study. | lower urinary tract symptoms (luts) and benign prostatic hyperplasia increase with age. to date, several medications are available to treat luts, including herbal remedies which offer less side effects but lack robust efficacy studies. | 2016 | 26049866 |
| recurrent urinary tract infections in children: preventive interventions other than prophylactic antibiotics. | urinary tract infection (uti) is one of the most common childhood infections. permanent renal cortical scarring may occur in affected children, especially with recurrent utis, leading to long-term complications such as hypertension and chronic renal failure. to prevent such damage, several interventions to prevent uti recurrences have been tried. the most established and accepted prevention at present is low dose long-term antibiotic prophylaxis. however it has a risk of break through infections ... | 2015 | 26140267 |
| are high proanthocyanidins key to cranberry efficacy in the prevention of recurrent urinary tract infection? | most research on american cranberry in the prevention of urinary tract infection (uti) has used juices. the spectrum of components in juice is limited. this study tested whether whole cranberry fruit powder (proanthocyanidin content 0.56%) could prevent recurrent uti in 182 women with two or more uti episodes in the last year. participants were randomized to a cranberry (n = 89) or a placebo group (n = 93) and received daily 500 mg of cranberry for 6 months. the number of uti diagnoses was count ... | 2015 | 26268913 |
| cranberry extract-enriched diets increase nad(p)h:quinone oxidoreductase and catalase activities in obese but not in nonobese mice. | consumption of antioxidant-enriched diets is 1 method of addressing obesity, which is associated with chronic oxidative stress and changes in the activity/expression of various enzymes. in this study, we hypothesized that the modulation of antioxidant enzymes and redox status through a cranberry extract (cbe)-enriched diet would differ between obese and nonobese mice. the cbe used in this study was obtained from the american cranberry (vaccinium macrocarpon, ericaceae), a popular constituent of ... | 2015 | 26319613 |
| in vivo consumption of cranberry exerts ex vivo antiadhesive activity against fimh-dominated uropathogenic escherichia coli: a combined in vivo, ex vivo, and in vitro study of an extract from vaccinium macrocarpon. | for investigation of the molecular interaction of cranberry extract with adhesins of uropathogenic escherichia coli (upec), urine from four volunteers consuming standardized cranberry extract (proanthocyanidin content = 1.24%) was analyzed within ex vivo experiments, indicating time-dependent significant inhibition of 40-50% of bacterial adhesion of upec strain nu14 to human t24 bladder cells. under in vitro conditions a dose-dependent increase in bacterial adhesion was observed with proanthocya ... | 2015 | 26330108 |
| de novo sequencing and analysis of the cranberry fruit transcriptome to identify putative genes involved in flavonoid biosynthesis, transport and regulation. | cranberries (vaccinium macrocarpon ait.), renowned for their excellent health benefits, are an important berry crop. here, we performed transcriptome sequencing of one cranberry cultivar, from fruits at two different developmental stages, on the illumina hiseq 2000 platform. our main goals were to identify putative genes for major metabolic pathways of bioactive compounds and compare the expression patterns between white fruit (w) and red fruit (r) in cranberry. | 2015 | 26330221 |
| influence of accelerated solvent extraction and ultrasound-assisted extraction on the anthocyanin profile of different vaccinium species in the context of statistical models for authentication. | anthocyanins are frequently discussed as marker compounds for fruit product authenticity. proper analysis including sample preparation for the determination of anthocyanin concentrations is crucial for the comparability of authenticity data. the present study determined the influence of accelerated solvent extraction (ase) and ultrasound-assisted extraction (uae), using two different solvent compositions on the anthocyanin profile of bilberries (vaccinium myrtillus l.), lowbush blueberries (vacc ... | 2015 | 26330254 |
| comparison of the anti-adhesion activity of three different cranberry extracts on uropathogenic p-fimbriated escherichia coli: a randomized, double-blind, placebo controlled, ex vivo, acute study. | research suggests that cranberry (vaccinium macrocarpon) helps maintain urinary tract health. bacterial adhesion to the uroepithelium is the initial step in the progression to development of a urinary tract infection. the bacterial anti-adhesion activity of cranberry proanthocyanidins (pacs) has been demonstrated in vitro. three different cranberry extracts were developed containing a standardized level of 36 mg of pacs. this randomized, double-blind, placebo controlled, ex vivo, acute study was ... | 2015 | 26411014 |
| cranberry (vaccinium macrocarpon) oligosaccharides decrease biofilm formation by uropathogenic escherichia coli. | the preventive effects of the american cranberry (vaccinium macrocarpon) against urinary tract infections are supported by extensive studies which have primarily focused on its phenolic constituents. herein, a phenolic-free carbohydrate fraction (designated cranf1b-f2) was purified from cranberry fruit using ion exchange and size exclusion chromatography. maldi-tof-ms analysis revealed that the cranf1b-f2 constituents are predominantly oligosaccharides possessing various degrees of polymerisatio ... | 2015 | 26613004 |
| adjuvant effect of cranberry proanthocyanidin active fraction on antivirulent property of ciprofloxacin against pseudomonas aeruginosa. | quorum sensing inhibitors (qsis) act as antivirulent agents since quorum sensing (qs) plays a vital role in regulating pathogenesis of pseudomonas aeruginosa. however, application of single qsi may not be effective as pathogen is vulnerable to successful mutations. in such conditions, combination of qsis can be exploited as there can be synergistic or adjuvant action. in the present study, we evaluated the antivirulence efficacy of combination of vaccinium macrocarpon proanthocyanidin active fra ... | 2016 | 26620081 |
| in vitro activity of vaccinium macrocarpon (cranberry) on urinary tract pathogens in uncomplicated urinary tract infection. | urinary tract infection is the most common bacterial infection in the community, mainly caused by escherichia coli (e coli). due to its high incidence and recurrence, problems are faced in the treatment with antibiotics. cranberry being herbal remedy have long been the focus of interest for their beneficial effects in preventing urinary tract infections. this study was conducted to analyse in vitro activity of cranberry (vaccinium macrocarpon) on uropathogenic e coli in uncomplicated urinary tra ... | 2016 | 26721034 |
| phosphodiesters as mycorrhizal p sources: ii. ericoid mycorrhiza and the utilization of nuclei as a phosphorus and nitrogen source by vaccinium macrocarpon. | mycorrhizal plants of vaccinium mocrocarpon aiton used nuclei from salmon sperm as a sole source of phosphorus (p) and achieved similar yields, p content and p concentration to plants crown with orthophosphate. mycorrhizal infection significantly increased the effectiveness of utilization of both inorganic and organic (nuclei) sources of p by vaccinium but in the case of the organic source this involved providing access to p which was completely unavailable to the uninfected plants. the results ... | 1996 | 26763640 |
| natural antimicrobials and oral microorganisms: a systematic review on herbal interventions for the eradication of multispecies oral biofilms. | oral diseases such as caries and periodontitis are mainly caused by microbial biofilms. antibiotic therapy has reached its limits with regard to antimicrobial resistance, and new therapeutic measures utilizing natural phytochemicals are currently a focus of research. hence, this systematic review provides a critical presentation of the antimicrobial effects of various medicinal herbs against in vitro, ex vivo, and in situ formed multispecies oral biofilms. searches were performed in three englis ... | 2015 | 26834707 |
| a critical approach to evaluating clinical efficacy, adverse events and drug interactions of herbal remedies. | systematic reviews and meta-analyses represent the uppermost ladders in the hierarchy of evidence. systematic reviews/meta-analyses suggest preliminary or satisfactory clinical evidence for agnus castus (vitex agnus castus) for premenstrual complaints, flaxseed (linum usitatissimum) for hypertension, feverfew (tanacetum partenium) for migraine prevention, ginger (zingiber officinalis) for pregnancy-induced nausea, ginseng (panax ginseng) for improving fasting glucose levels as well as phytoestro ... | 2016 | 26887532 |
| antibacterial activity of isolated phenolic compounds from cranberry (vaccinium macrocarpon) against escherichia coli. | phenolic compounds from a cranberry extract were isolated in order to assess their contribution to the antibacterial activity against uropathogenic strains of escherichia coli (upec). with this purpose, a total of 25 fractions from a cranberry extract were isolated using semipreparative high performance liquid chromatography (hplc) and characterized based on the results obtained by reversed-phase hplc coupled to mass spectrometry detection. then, the effects on upec surface hydrophobicity and bi ... | 2016 | 26902395 |
| cranberry resistance to dodder parasitism: induced chemical defenses and behavior of a parasitic plant. | parasitic plants are common in many ecosystems, where they can structure community interactions and cause major economic damage. for example, parasitic dodder (cuscuta spp.) can cause up to 80-100 % yield loss in heavily infested cranberry (vaccinium macrocarpon) patches. despite their ecological and economic importance, remarkably little is known about how parasitic plants affect, or are affected by, host chemistry. to examine chemically-mediated interactions between dodder and its cranberry ho ... | 2016 | 26905738 |
| authentication of punica granatum l.: development of scar markers for the detection of 10 fruits potentially used in economically motivated adulteration. | the large commercial success of pomegranate increase the likelihood of economically motivated adulteration (ema), which has been gradually spotted with the undeclared addition of anthocyanin-rich plants or cheaper fruit juices used as bulking and diluting agents. a method based on sequence-characterized amplified regions (scars) was developed to detect the presence of aristotelia chilensis, aronia melanocarpa, dioscorea alata, euterpe oleracea, malus×domestica, morus nigra, sambucus nigra, vacci ... | 2016 | 26920316 |
| anti-adhesion activity of a2-type proanthocyanidins (a cranberry major component) on uropathogenic e. coli and p. mirabilis strains. | urinary tract infections (utis) are relatively common in women and may be classified as uncomplicated or complicated, depending upon the urinary tract anatomy and physiology. acute uncomplicated cystitis (auc) occurs when urinary pathogens from the bowel or vagina colonize the periurethral mucosa and reach the bladder. the vast majority of episodes in healthy women involving the same bacterial strain that caused the initial infection are thought to be reinfections. about 90% of auc are caused by ... | 2014 | 27025740 |
| fragman: an r package for fragment analysis. | determination of microsatellite lengths or other dna fragment types is an important initial component of many genetic studies such as mutation detection, linkage and quantitative trait loci (qtl) mapping, genetic diversity, pedigree analysis, and detection of heterozygosity. a handful of commercial and freely available software programs exist for fragment analysis; however, most of them are platform dependent and lack high-throughput applicability. | 2016 | 27098093 |
| effects of cranberry components on il-1β-stimulated production of il-6, il-8 and vegf by human tmj synovial fibroblasts. | osteoarthritis (oa) in the tmj is characterized by deterioration of articular cartilage and secondary inflammatory changes. interleukin-1β (il-1β) stimulates il-6, il-8, and vascular endothelial growth factor (vegf) in synovial fluid of tmj with internal derangement and bony changes. the cranberry (vaccinium macrocarpon) contains polyphenolic compounds that inhibit production of pro-inflammatory molecules by gingival cells in response to several stimulators. this study examined effects of cranbe ... | 2016 | 27107382 |
| anti-inflammatory activity of berry fruits in mice model of inflammation is based on oxidative stress modulation. | many fruits have been used as nutraceuticals because the presence of bioactive molecules that play biological activities. | 2016 | 27114691 |
| temperature-mediated growth thresholds of acrobasis vaccinii (lepidoptera: pyralidae). | degree-day models link ambient temperature to the development of insects, making such models valuable tools in integrated pest management. these models increase management efficacy by quantifying and predicting pest phenology. in wisconsin, the top insect pest of cranberry production is the cranberry fruitworm, acrobasis vaccinii riley (lepidoptera: pyralidae). control of this species is often complicated by the fact that the larvae feed entirely within the fruit. timing of control tactics, ther ... | 2016 | 27174127 |
| characterization of the key aroma volatile compounds in cranberry (vaccinium macrocarpon ait.) using gas chromatography-olfactometry (gc-o) and odor activity value (oav). | the volatile compounds of cranberries obtained from four cultivars (early black, y1; howes, y2; searles, y3; and mcfarlin, y4) were analyzed by gas chromatography-olfactometry (gc-o), gas chromatography-mass spectrometry (gc-ms), and gc-flame photometric detection (fpd). the result presented that a total of thirty-three, thirty-four, thirty-four, and thirty-six odor-active compounds were identified by gc-o in the y1, y2, y3, and y4, respectively. in addition, twenty-two, twenty-two, thirty, and ... | 2016 | 27265519 |
| natural cures for breast cancer treatment. | for centuries, herbs and plants have been used for medicinal purposes and as food as well. this review concerns about different types of plants that retain the immune stimulating and anti-tumor properties. large variety of active phytochemicals such as carotenoids, flavonoids, ligands, polyphenolics, terpenoids, sulfides, lignans and plant sterols has been identified in different types of herbs. these phytochemicals have different mechanisms of action. they either stimulate the protective enzyme ... | 2016 | 27275107 |
| exploiting genotyping by sequencing to characterize the genomic structure of the american cranberry through high-density linkage mapping. | the application of genotyping by sequencing (gbs) approaches, combined with data imputation methodologies, is narrowing the genetic knowledge gap between major and understudied, minor crops. gbs is an excellent tool to characterize the genomic structure of recently domesticated (~200 years) and understudied species, such as cranberry (vaccinium macrocarpon ait.), by generating large numbers of markers for genomic studies such as genetic mapping. | 2016 | 27295982 |
| effect of oral cranberry extract (standardized proanthocyanidin-a) in patients with recurrent uti by pathogenic e. coli: a randomized placebo-controlled clinical research study. | to evaluate the effect of cranberry extract (pac-a ~ proanthocyanidin-a) on the in vitro bacterial properties of uropathogenic (e. coli) and its efficacy/tolerability in patients with subclinical or uncomplicated recurrent uti (r-uti). | 2016 | 27314247 |
| inhibition of herpes simplex type 1 and type 2 infections by oximacro(®), a cranberry extract with a high content of a-type proanthocyanidins (pacs-a). | in the absence of efficient preventive vaccines, topical microbicides offer an attractive alternative in the prevention of herpes simplex type 1 (hsv-1) and type 2 (hsv-2) infections. because of their recognized anti-adhesive activity against bacterial pathogens, cranberry (vaccinium macrocarpon ait.) extracts may represent a natural source of new antiviral microbicides. however, few studies have addressed the applications of cranberry extract as a direct-acting antiviral agent. here, we report ... | 2016 | 27321663 |
| antiurease and anti-oxidant activity of vaccinium macrocarpon fruit. | the objective of present study was to evaluate the antiurease and anti-oxidant activity of vaccinium macrocarpon fruit. the parent extract was ethanolic extract while its sub fractions were prepared in n-hexane, chloroform and n-butanol. the method based on scavenging activity and reduction capability of 1, 1-diphenyl-2-picrylhydrazyl radical (dpph). n-butanol fraction was the most effective antioxidant with 87.0±1.15 activity but the activity was less than ascorbic acid i.e. 93.74±0.12. highly ... | 2016 | 27592488 |
| cranberry extract attenuates hepatic inflammation in high-fat-fed obese mice. | cranberry (vaccinium macrocarpon) consumption has been associated with health beneficial effects. nonalcoholic fatty liver disease (nafld) is a comorbidity of obesity. in the present study, we investigated the effect of a polyphenol-rich cranberry extract (cbe) on hepatic inflammation in high fat (hf)-fed obese c57bl/6j mice. following dietary treatment with 0.8% cbe for 10 weeks, we observed no change in body weight or visceral fat mass in cbe-supplemented mice compared to hf-fed control mice. ... | 2016 | 27619543 |
| botanicals and their bioactive phytochemicals for women's health. | botanical dietary supplements are increasingly popular for women's health, particularly for older women. the specific botanicals women take vary as a function of age. younger women will use botanicals for urinary tract infections, especially vaccinium macrocarpon (cranberry), where there is evidence for efficacy. botanical dietary supplements for premenstrual syndrome (pms) are less commonly used, and rigorous clinical trials have not been done. some examples include vitex agnus-castus (chastebe ... | 2016 | 27677719 |
| [erectile dysfunction - treatment with substances of natural origin]. | the article discusses erectile dysfunction (ed) with the special emphasis on epidemiology, as well as the currently available medical treatments. describing treatment methods authors paid special attention to natural therapies (as panax ginseng, tribulus terrestris, vaccinium macrocarpon), because taking into consideration their safety profile, they appear to be an important alternative to therapies with synthetic molecules. from substances of natural origin, extract from the fruit of tribulus t ... | 2017 | 27717948 |
| cranberry intervention in patients with prostate cancer prior to radical prostatectomy. clinical, pathological and laboratory findings. | recently, we described an inverse association between cranberry supplementation and serum prostate specific antigen (psa) in patients with negative biopsy for prostate cancer (pca) and chronic nonbacterial prostatitis. this double blind placebo controlled study evaluates the effects of cranberry consumption on psa values and other markers in men with pca before radical prostatectomy. | 2016 | 27833172 |
| phenolics of selected cranberry genotypes (vaccinium macrocarpon ait.) and their antioxidant efficacy. | free, esterified, and bound phenolic fractions of berries from five different cranberry genotypes and two market samples were evaluated for their total phenolic, flavonoid, and monomeric anthocyanin contents as well as their antioxidant efficacy using teac, orac, dpph radical, reducing power, and ferrous ion chelation capacity assays. hplc-ms/ms analysis was performed for two of the rich sources (pilgrim and wild clone nl2) of phenolics and high antioxidant activity. among the genotypes, pilgrim ... | 2016 | 27960275 |
| potential health benefits and quality of dried fruits: goji fruits, cranberries and raisins. | dried fruits are important snacks and additives to other foods due to their taste and nutritional advantages. therefore there is an important goal to control the quality of the food on the market for consumer's safety. antioxidant activity of goji fruits (lycium barbarum), cranberries (vaccinium macrocarpon and oxycoccus) and raisins (vitis vinifera) were studied using the dpph (2,2-diphenyl-1-picrylhydrazyl) and folin-ciocalteu assays. cu, mn and ge influencing antioxidant activity were determi ... | 0 | 27979197 |
| flight synchrony among the major moth pests of cranberries in the upper midwest, usa. | the cranberry fruitworm (acrobasis vaccinii riley), sparganothis fruitworm (sparganothis sulfureana clemens), and blackheaded fireworm (rhopobota naevana hübner) are historically significant pests of cranberries (vaccinium macrocarpon aiton) in the upper midwest (wisconsin), usa. their respective natural histories are well documented but correlations between developmental benchmarks (e.g., larval eclosion) and degree-day accruals are not yet known. treatment timings are critical to the optimizat ... | 2017 | 28245642 |
| construction of a high-density american cranberry (vaccinium macrocarpon ait.) composite map using genotyping-by-sequencing for multi-pedigree linkage mapping. | the american cranberry (vaccinium macrocarpon ait.) is a recently domesticated, economically important, fruit crop with limited molecular resources. new genetic resources could accelerate genetic gain in cranberry through characterization of its genomic structure and by enabling molecular-assisted breeding strategies. to increase the availability of cranberry genomic resources, genotyping-by-sequencing (gbs) was used to discover and genotype thousands of single nucleotide polymorphisms (snps) wi ... | 2017 | 28250016 |
| protein-bound vaccinium fruit polyphenols decrease ige binding to peanut allergens and rbl-2h3 mast cell degranulation in vitro. | peanut allergy is a worldwide health concern. in this study, the natural binding properties of plant-derived polyphenols to proteins was leveraged to produce stable protein-polyphenol complexes comprised of peanut proteins and cranberry (vaccinium macrocarpon ait.) or lowbush blueberry (vaccinium angustifolium ait.) pomace polyphenols. protein-bound and free polyphenols were characterized and quantified by multistep extraction of polyphenols from protein-polyphenol complexes. immunoblotting was ... | 2017 | 28294257 |
| reproductive trade-offs in genetically distinct clones ofvaccinium macrocarpon, the american cranberry. | patterns of resource allocation to growth, current reproduction, and potential future reproduction were quantified in six genetically distinct cultivars ofvaccinium macrocarpon. for all cultivars (genotypes), vegetative size is positively correlated with some measures of current reproduction (fruit and flower number) but negatively correlated with others (seed number per fruit, seed weight per fruit). vegetative growth in the current year is significantly related to the production of reproductiv ... | 1996 | 28307192 |
| [erectile dysfunction - treatment with substances of natural origin]. | the article discusses erectile dysfunction (ed) with the special emphasis on epidemiology, as well as the currently available medical treatments. describing treatment methods authors paid special attention to natural therapies (as panax ginseng, tribulus terrestris, vaccinium macrocarpon), because taking into consideration their safety profile, they appear to be an important alternative to therapies with synthetic molecules. from substances of natural origin, extract from the fruit of tribulus t ... | 2016 | 28478429 |
| enteric-coated and highly standardized cranberry extract reduces antibiotic and nonsteroidal anti-inflammatory drug use for urinary tract infections during radiotherapy for prostate carcinoma. | worldwide, bacterial resistance to antibiotic therapy is a major concern for the medical community. antibiotic resistance mainly affects gram-negative bacteria that are an important cause of lower urinary tract infections (lutis). pelvic irradiation for prostate cancer is a risk factor for lutis. cranberry extract is reported to reduce the incidence of lutis. the prophylactic role of an enteric-coated, highly standardized cranberry extract (vo370(®)) in reducing luti episodes, urinary discomfort ... | 2017 | 28491861 |