Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| ultrastructural cytopathology of mouse myocardium associated with emc viral infection. | 1973 | 4348560 | |
| enhancement of interferon production of murine peritoneal leukocytes by mineral oil: the effect of experimental emc infection in mice. | 1973 | 4349471 | |
| specificity in initiation of protein synthesis in a fractionated mammalian cell-free system. | 1973 | 4349564 | |
| virus-induced diabetes mellitus. i. hyperglycemia and hypoinsulinemia in mice infected with encephalomyocarditis virus. | infection of dba/2n male mice with encephalomyocarditis virus resulted in a diabeteslike syndrome characterized by hyperglycemia, glycosuria, hypoinsulinemia, polydipsia, and polyphagia. blood glucose levels were elevated within 4 days after infection and reached a maximum mean level of 320 mg/100 ml within 12 days. approximately 60-80% of the animals developed a transient hyperglycemia while 10-15% of the animals remained hyperglycemic for well over 6 mo. the remaining animals failed to become ... | 1973 | 4349751 |
| persistent infection of mouse cells with sindbis virus: role of virulence of strains, auto-interfering particles and interferon. | 1973 | 4356681 | |
| the effect of ethidium bromide on l cells and encephalomyocarditis virus replication. | 1973 | 4356683 | |
| specificity of reticulocyte initiation factors for the translation of globin messenger rna. | 1973 | 4356821 | |
| inhibition of protein synthesis directed by added viral and cellular messenger rnas in extracts of interferon-treated ehrlich ascites tumor cells. location and dominance of the inhibitor(s). | 1973 | 4356983 | |
| a comparison of the virus-specific polypeptides of encephalomyocarditis virus, human rhinovirus-1a, and poliovirus. | 1973 | 4357051 | |
| encephalomyocarditis virus activity in mus booduga (gray) in barur village (1961-1962), sagar kfd area, mysore state, india. | 1973 | 4357094 | |
| detection of encephalomyocarditis virus infection in animal cells by gas liquid chromatography. | 1973 | 4357193 | |
| size differences in the ribonucleic acids of feline leukaemia viruses. | 1973 | 4357376 | |
| [antiviral activity of components of echinacea purpurea]. | 1973 | 4358341 | |
| encephalomyocarditis (emc) virus infection of the mouse aorta. an ultrastructural study. | 1973 | 4355169 | |
| propionin b, an antiviral principle of propionibacteria. | 1973 | 4355824 | |
| [detection of complement fixing antibodies against herpes simplex virus (and other neurotropic viruses) in patients with multiple sclerosis]. | 1973 | 4350584 | |
| mechanism of interferon uptake in parental and somatic monkey-mouse hybrid cells. | dose-response curves of interferons in different sensitive cells are regularly sigmoidal. in somatic monkey-mouse hybrid cells, however, a significant decrease in the slope of the curve for primate interferon was observed, while the dose-response effect was unaltered for mouse interferon. high concentrations of primate interferon were 10- to 100-times less effective in hybrid clones than in parental monkey cv-1 cells; at low concentrations the antiviral effect was 10- to 20-times higher in hybri ... | 1973 | 4346894 |
| encephalomyocarditis virus (e variant) in mice. pancreatic changes. | 1973 | 4348435 | |
| the initiation of protein synthesis directed by the rna from encephalomyocarditis virus. | 1973 | 4348443 | |
| new isothiazole derivatives. ii. cytotoxicity and antiviral activity in tissue cultures. | 1973 | 4361627 | |
| antiviral activity of tobacco smoke condensate on encephalomyocarditis infection in mice. | a water-soluble nontumorigenic acidic fraction of tobacco smoke condensate of cigarettes has been found to have antiviral activity against encephalomyocarditis (emc) virus infection in mice. the portion of lower molecular weight was inhibitory to the growth of emc virus, vesicular stomatitis virus, reovirus type 2, vaccinia virus, and poliovirus type 2, but not against adenovirus type 12, in kb cell cultures. the cigarette smoke agent did not induce serum interferon although it protected mice fr ... | 1973 | 4364177 |
| n,n-dioctadecyl-n',n'-bis(2-hydroxyethyl) propanediamine: antiviral activity and interferon stimulation in mice. | cp-20,961, n,n-dioctadecyl-n', n'-bis(2-hydroxyethyl)propanediamine, is an antiviral drug with low acute toxicity in mice. parenteral injection of this compound protected mice against lethal infections with encephalomyocarditis and semliki forest viruses and effectively suppressed pox formation by vaccinia infection. maximal antiviral effects were observed when cp-20,961 was administered 6 to 12 h before infection. an interferon detected in plasma 12 to 20 h after the drug was given appeared to ... | 1973 | 4364178 |
| a correlation between the buoyant density and the sedimentation coefficient of emc viral polyribosomes. | 1973 | 4359147 | |
| the effect of certain amino acids on reproduction of encephalomyocarditis virus. ii. investigation of the inhibiting effect of l-histidine. | 1973 | 4359174 | |
| biochemical and biophysical characterization of calicivirus isolates from pinnipeds. | 1973 | 4359761 | |
| interferon assay based on the inhibition of double-stranded reovirus rna accumulation in mouse l cells. | 1973 | 4360633 | |
| typhoid-paratyphoid (tab) vaccine as interferon inducer in mice. | 1973 | 4358715 | |
| the in vitro effect of cyclophosphamide on col. mm virus replication and interferon production. | 1973 | 4358716 | |
| role of incomplete viruses and interferon in persistent infection of mouse cells with sindbis virus. | 1973 | 4358717 | |
| antiviral effect of interferon covalently bound to sepharose. | interferon, covalently bound to sepharose 4b activated by cyanogen bromide, induces the antiviral state in sensitive cells. the antiviral effect is neutralized by antiserum specific to interferon and is recovered thereafter when the antibody is detached from the interferon by treatment at low ph. binding interferon to sepharose increases the stability of the molecule. it is likely that the interferon molecule acts on the cell receptor without being detached from the beads. however, the data do n ... | 1973 | 4365374 |
| stimulation of restricted reproduction of emc virus in hela cells by non-replicating poliovirus. | 1973 | 4119353 | |
| neutralization of infectious me (maus-elberfeld) virus-antibody complexes by anti-gamma-globulin antibody. | 1973 | 4129412 | |
| viral encephalitis. | 1973 | 4144386 | |
| interferon tolerance and antiviral protection in mice given single or multiple injections of endotoxin or poly i : c. | 1973 | 4147139 | |
| interferon induction by detoxicated bacterial endotoxins. | 1973 | 4150031 | |
| changes in isoelectric points of chromatin deoxyribonucleoproteins from krebs ii cells after infection with encephalomyocarditis virus. | 1973 | 4150035 | |
| insecticide and viral interaction as a cause of fatty visceral changes and encephalopathy in the mouse. | 1974 | 4134409 | |
| [study of the interaction of the replicative form of the rna of the encephalomyocarditis virus with actinomycin]. | 1974 | 4140617 | |
| cleavage of mengovirus polyproteins in vivo. | the synthesis of mengovirus-specific proteins in vivo was studied by labeling the viral proteins with radioactive amino acids under conditions in which host protein synthesis was almost completely inhibited. pulse-chase experiments enabled the kinetic analysis of the cleavages of certain viral protein precursors and the formation of others. the pattern of cleavages of mengovirus precursor polypeptides is similar to that of encephalomyocarditis virus. the major difference between the two viruses ... | 1974 | 4367902 |
| regulation of protein synthesis during density-dependent growth inhibition of bhk21-13 cells. | 1974 | 4364657 | |
| virus-induced diabetes mellitus. ii. relationship between beta cell damage and hyperglycemia in mice infected with encephalomyocarditis virus. | infection of dba 2 male mice with the m variant of encephalomyocarditis virus resulted in a diabetes-like syndrome. histologic examination of the pancreas revealed damage to the beta cells with little involvement of the acinar cells. the severity of the hyperglycemia correlated closely with the degree of beta cell damage. by immunofluorescence, viral antigens could be detected in the beta cells during the first 10 days of the infection. in contrast to the response found in male dba 2 mice, infec ... | 1974 | 4363478 |
| the polypeptide composition of the encephalomyocarditis virus particle. | 1974 | 4365488 | |
| [role of viruses in cardiac pathology]. | 1974 | 4365756 | |
| encephalomyocarditis virus infection of mouse plasmacytoma cells. i. inhibition of cellular protein synthesis. | mouse plasmacytoma ascites tumor cells (mopc 460) were efficiently infected with encephalomyocarditis virus. inhibition of host protein synthesis was evident after 2 h and complete by 4 h postinfection. the mechanism by which virus infection results in inhibition of host cell protein synthesis was studied in vitro. cell-free protein-synthesizing systems, prepared from uninfected and infected cells, were found to be equally active with respect to their abilities to translate cellular and viral mr ... | 1974 | 4368674 |
| in vitro synthesis of structural proteins of semliki forest virus directed by isolated 26 s rna from infected cells. | 1974 | 4368800 | |
| interferon bioassay methods and the development of standard procedures: a critique and analysis of current observations. | 1974 | 4377882 | |
| editorial: viruses and arteriosclerosis. | 1974 | 4361469 | |
| genetic influences affecting the occurrence of a diabetes mellitus-like disease in mice infected with the encephalomyocarditis virus. | the m variant of encephalomyocarditis virus produces a diabetes mellitus-like disease in dba/2 mice but not in animals of the c3h strain. fewer than one-third of infected f(1) (dba/2 x c3h) progeny exhibit the disease, whereas the prevalence in backcrosses (f(1) x dba/2, f(1) x c3h) is comparable to the parental inbred strain. thus, the mode of inheritance of the diabetic predisposition appears to be polygenic. dba/2 animals develop striking inflammatory and necrotizing lesions of the islets of ... | 1974 | 4359400 |
| lesions of the islets of langerhans in encephalomyocarditis virus-infected mice with diabetes mellitus-like disease. i. acute lesions. | mice infected with the m variant of the encephalomyocarditis (emc) virus develop lesions of the islets of langerhans associated with a diabetes mellitus-like disease. ultrastructural alterations become evident in capillaries and beta cells at a time when large amounts of virus are present in the pancreatic tissue. although some beta cells become necrotic, degranulation and contraction of intact cells is the prominent lesion. changes in the capillaries appear early in the course of the infection ... | 1974 | 4359734 |
| rna ligase activity in phage-infected bacteria and animal cells. | 1974 | 4364393 | |
| presence of a large poly(rc) tract within the rna of encephalomyocarditis virus. | 1974 | 4364433 | |
| oral induction of interferon by a low-molecular-weight compound. | 1974 | 4362004 | |
| [translation of cellular and viral information rna in extracts from cells infected with encephalomyocarditis viruses]. | 1974 | 4362233 | |
| phagocytosis of injured hepatocytes following inoculation with encephalomyocarditis virus. | 1974 | 4363126 | |
| studies on the replicase of encephalomyocarditis virus. | 1974 | 4366015 | |
| increased sensitivity of cell-free protein synthesis to double-stranded rna after interferon treatment. | 1974 | 4366491 | |
| the mechanism of viral replication. structure of replication complexes of encephalomyocarditis virus. | the structure of the purified replicative intermediate of encephalomyocarditis virus was determined by electron microscopy. approximately 80% of the replicative intermediate complexes were characterized by a filament of double-stranded rna of widely variable length, which had a "bush" of single-stranded rna at one end. in many examples one or more additional single-stranded bushes were appended internally to the double-stranded rna filament. these results support the view that before deproteiniz ... | 1974 | 4366773 |
| inactivation of some bacterial and animal viruses by exposure to liquid-air interfaces. | 1974 | 4367307 | |
| bis-basic-substituted polycyclic aromatic compounds. a new class of antiviral agents. 2. tilorone and related bis-basic ethers of fluorenone, fluorenol, and fluorene. | 1974 | 4367593 | |
| bis-basic-substituted polycyclic aromatic compounds. a new class of antiviral agents. 3. 2,7-bis(aminoacyl)fluorenes and -fluorenones. | 1974 | 4367594 | |
| bis-basic-substituted polycyclic aromatic compounds. a new class of antiviral agents. 4. bis-basic sulfonamides of anthraquinone. | 1974 | 4367595 | |
| glucose intolerance in mice infected with encephalomyocarditis virus. | 1974 | 4367721 | |
| the rate of polypeptide chain elongation in a cell-free system from krebs ii ascites cells. | 1974 | 4364993 | |
| release of the inhibition of messenger rna translation in extracts of interferon-treated ehrlich ascites tumor cells by added transfer rna. | 1974 | 4363942 | |
| pancreatitis of mice infected with encephalomyocarditis virus. | 1974 | 4365521 | |
| [oligomers of the replicative form of encephalomyocarditis virus rna]. | 1974 | 4365610 | |
| hyporeactivity of tissue cultures. | 1974 | 4365729 | |
| microtiter hemagglutination-inhibition test for the detection of encephalomyocarditis virus antibodies. | several variables were found to affect the agglutination of sheep erythrocytes by encephalomyocarditis virus. a satisfactory and reliable microtiter hemagglutination-inhibition test is described. | 1974 | 4358861 |
| inactivation of encephalomyocarditis virus in aerosols: fate of virus protein and ribonucleic acid. | after aerosolization at relative humidities of 50% or lower, encephalomyocarditis virus is rapidly inactivated. in this process the protein coat of the virion is damaged. this appears as a loss of hemagglutination activity and loss of affinity for hemagglutination inhibiting antibodies. the ribonucleic acid of the virus retains its infectivity but it becomes susceptible to ribonuclease. it sediments in sucrose gradients when centrifuged at high speed with the same velocity as free infectious rib ... | 1974 | 4358862 |
| erythrocyte association and interferon production by minute virus of mice. | 1974 | 4363906 | |
| efficiency of translation of viral and cellular mrna's in extracts from cells infected with encephalomyocarditis virus. | the relative efficiency of translation of host cell mrna and encephalomyocarditis (emc) virus rna has been investigated in cell-free preparations from uninfected and emc virus-infected drebs-ii cells. the ability of cell-free extracts from infected cells to translate exogenously-added emc virus rna and total krebs-ii cell mrna was markedly diminished, but no evidence for the selective inhibition of translation of host cell mrna in these systems was obtained. | 1974 | 4376807 |
| characterization of the large picornaviral polypeptides produced in the presence of zinc ion. | zinc ion inhibits the posttranslational cleavages of human rhinovirus-1a, encephalomyocarditis virus, and poliovirus polypeptides. each virus displayed a different susceptibility to zinc. however, in each case the cleavages of the capsid precursor and the cleavages analogous to the c --> d --> e conversion in encephalomyocarditis virus were most sensitive to zinc. higher concentrations of zinc resulted in the buildup of even larger precursor polypeptides of a size between 106,000 and 214,000 dal ... | 1974 | 4367904 |
| amylase isoenzymes during viral infections of the pancreas and salivary glands. | 1974 | 4362566 | |
| encephalomyocarditis virus infection of mouse plasmacytoma cells. ii. effect on host rna synthesis and rna polymerases. | the effect of encephalomyocarditis virus infection of mopc 460 mouse plasmacytoma cells on host rna synthesis and rna polymerases was investigated. consistent with work performed in other virus host systems, rates of rna synthesis appeared to be inhibited in infected cells, whereas rna degradation appeared normal. these results were further extended with isolated nuclei, in which distinct rna polymerase activities could be studied under conditions where problems with rna turnover and endogenous ... | 1974 | 4368675 |
| selective inhibition of the synthesis of single-stranded rna of encephalomyocarditis virus by 2-(alpha-hydroxybenzyl)-benzimidazole in cell-free systems. | 1974 | 4370357 | |
| lead aggravates viral disease and represses the antiviral activity of interferon inducers. | lead acetate was administered continuously in the drinking water to cd-1 male mice beginning at 4 weeks of age. an ld(10-20) of the lytic viruses or 300 plaque-forming units of rlv was inoculated intrapertioneally at 6 weeks of age. lead increased the response of the mice to all classes of viruses against which it was tested: an rna picornavirus-encephalomyocarditis (emcv), a dna herpesvirus-pseudoribies, an rna leukemia-virus-rauscher leukemia (rlv), an rna arbovirus b-st. louis encephalitis, a ... | 1974 | 4364644 |
| viral infections of the central nervous system. | 1974 | 4362722 | |
| [the antiviral properties of corynebacterium parvum]. | 1974 | 4376977 | |
| viruses in experimental and human diabetes. | 1974 | 4377456 | |
| competition between eukaryotic messenger rnas in cell-free protein synthesis. | 1974 | 4377720 | |
| [etiology of encephalomyocarditis in rhesus monkeys]. | 1974 | 4368130 | |
| the synthesis of encephalomyocarditis virus polypeptides in infected l-cells and cell-free systems. | 1974 | 4369366 | |
| virus-specific proteins associated with ribosomes of krebs-ii cells infected with encephalomyocarditis virus. | 1974 | 4369440 | |
| [effect of a selective inhibitor of ribosomal rna synthesis on the antiviral action of interferon]. | 1974 | 4369543 | |
| bis-basic-substituted polycyclic aromatic compounds. a new class of antiviral agents. 1,2 6. bis-basic-substituted fluoranthenes. | 1974 | 4369817 | |
| bis-basic-substituted polycyclic aromatic compounds. a new class of antiviral agents. 5. bis-basic ethers of anthraquinone and bisalkamine esters of anthraquinonedicarboxylic acids. | 1974 | 4369818 | |
| experimental encephalomyocarditis virus infection of pigs. | 1974 | 4370016 | |
| inhibition of interferon action by plant lectins. | 1974 | 4370104 | |
| replication of arboviruses in mouse organ cultures. i. results with middelburg virus in organ cultures and peritoneal macrophages. | 1974 | 4370336 | |
| the synthesis of virus-specific polypeptides on polyribosomes isolated from the cells infected with encephalomyocarditis virus. | 1974 | 4370505 | |
| characteristic ultrastructural changes in organs of newborn mice infected with emc virus. | 1974 | 4370623 | |
| virologic studies of multiple sclerosis and other chronic and relapsing neurological diseases. | 1974 | 4371203 | |
| pronounced antiviral activity of human interferon on bovine and porcine cells. | 1974 | 4371444 | |
| interferon inducers in therapy of infection with encephalomyocarditis virus in mice. i. effect of single doses of polyriboinosinic-polyribocytidylic acid and tilorone hydrochloride on viral pathogenesis. | 1974 | 4371528 | |
| interferon inducers in therapy of infection with encephalomyocarditis virus in mice. ii. effect of multiple doses of polyriboinosinic-polyribocytidylic acid on viral pathogenesis. | 1974 | 4371529 | |
| adaptation of influenza virus to growth in cultured murine methylcholanthrene induced tumors. | 1974 | 4371624 | |
| influence of immunosuppressive drugs on replication of col mm virus and productive of interferon in vivo. | 1974 | 4371712 | |
| the anti-virus activity of double-stranded rna in the presence of antibody to double-stranded rna. | 1974 | 4372061 | |
| interferon-sepharose: priming of l cells for induction of interferon by mm virus. | 1974 | 4372309 | |
| poly(c) in animal viral rnas. | 1974 | 4372534 |