Publications
Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
---|
refractoriness of kb cell cultures carrying japanese b encephalitis virus to encephalomyocarditis virus infection. | 1969 | 4307239 | |
[induction of interferon synthesis by double-stranded rna. i. application to the study of the multiplication cycle of mengo virus]. | 1969 | 4307590 | |
a persistent and inapparent infection of l cells with the virus of lymphocytic choriomeningitis. | 1969 | 4186351 | |
[formation of interferon in the brain of baby mice after injection with some rhabdoviruses]. | 1969 | 4393905 | |
relation of incubation temperature to interferon production in mouse peritoneal cells infected with newcastle disease virus. | 1969 | 4398703 | |
release of interferon by mouse peritoneal cells in vitro. the requirement of contact with endotoxin and the temperature dependence of release. | 1969 | 4398704 | |
[attempts to use the interference phenomenon for detecting several mice leukemia viruses in tissue culture]. | 1969 | 4320252 | |
[some properties of the replicative form of mouse encephalomyocarditis virus rna]. | 1969 | 4320269 | |
tilorone hydrochloride: an orally active antiviral agent. | tilorone hydrochloride, 2,7-bis[2-(diethylamino)ethoxy]fluoren-9-one dihydrochloride, given orally to mice before they are infected is active against at least nine viruses of both rna and dna groups. the compound is effective when given prophylactically; the optimum time of treatment depends on the route of infection. | 1970 | 4317923 |
[relations between rna molecular structure and their induction power on interferon]. | 1970 | 4320457 | |
rapid sensitive assay for interferons based on the inhibition of mm virus nucleic acid synthesis. | a method for assaying mouse interferon based on the inhibition of viral ribonucleic acid (rna) synthesis was devised. the amount of mm virus and rna synthesized in interferon-treated l-cell cultures was determined by measuring the amount of (3)h-uridine converted into a trichloroacetic acid-insoluble form after treatment of the infected cultures with 2.5 mug of actinomycin d per ml. the amount of rna synthesized was inversely related to the concentration of interferon used for treatment. a linea ... | 1970 | 4320919 |
abnormal dna patterns in animal mitochondria: ethidium bromide-induced breakdown of closed circular dna and conditions leading to oligomer accumulation. | treatment of cultured mouse fibroblasts (l-cells) and hamster kidney cells with ethidium bromide was found to inhibit the incorporation of [(3)h]thymidine into mitochondrial closed-circular dna, but not into nuclear dna. the specific activity of nuclear dna in treated cells was higher than in control cells. treatment also led to breakdown of closed-circular mitochondrial dna, greatly enlarged mitochondrial profiles with few or no cristae, and a higher yield of mitochondrial protein per cell.a si ... | 1970 | 4321352 |
effect of mengovirus replication on choline metabolism and membrane formation in novikoff hepatoma cells. | infection of novikoff rat hepatoma cells (subline nlsl-67) with mengovirus resulted in a two- to threefold increase in the rate of choline incorporation into membrane phosphatidylcholine at about 3 hr after infection, without affecting the rate of transport of choline into the cell or its phosphorylation. the time course of virus-stimulated phosphatidylcholine synthesis was compared with the time courses of other virus-induced processes during a single cycle of replication. the formation of vira ... | 1970 | 4322083 |
tilorone hydrochloride: mode of action. | an antiviral serum component is found in mice treated orally with tilorone hydrochloride. the active material fulfills sufficient biological criteria to be classified as an interferon. | 1970 | 4317924 |
protection against herpes virus and encephalomyocarditis virus encephalitis with a double-stranded rna inducer of interferon. | 1970 | 5414254 | |
release of an interferon-like virus inhibitor during contact of mouse leukocytes with target cells. | 1970 | 4392852 | |
delay of mengovirus-induced cytopathology in mitotic l-cells. | the time course and extent of mengovirus production were the same in metaphase-arrested and interphase l-cells, yet the expression of cytopathology was delayed several hours in metaphase cells. | 1970 | 4194170 |
interferon induction by and infectivity of ultraviolet-irradiated double- and multistranded viral rna's. | 1970 | 4323578 | |
[stimulating interaction of animal viruses]. | 1970 | 4323595 | |
studies of the early events of the replicative cycle of three variants of mengo encephalomyelitis virus in mouse fibroblast cells. | 1970 | 4322160 | |
[electron microscopic detection of mengovirus in l cells with ferritin-labeled antibodies]. | 1970 | 4322839 | |
[myocarditic component of some acute diseases in children]. | 1970 | 4321607 | |
preparation of an inactivated emc virus vaccine. | 1970 | 4321205 | |
growth of mouse l cells in shaken culture and mengovirus plaque formation on l cells suspended in agar. | procedures are described that require a minimum of equipment and maintenance for growing mouse l cells suspended in liquid medium and for plaquing mengovirus on l cells suspended in agar. viability of l cells during storage for 1 to 2 hr at relatively high concentrations was better in media at 30 c than at 0 c, as measured by viable counts after growth for 24 hr at 35 c. the number and size of plaques increased with increasing concentration of nahco(3) in the agar layers, but the relative differ ... | 1970 | 4320864 |
viral interference in the brains of mice infected subcutaneously with herpes simplex virus. | 1970 | 4320341 | |
comparison of agar and agarose preparations for mengovirus plaque formation. | an agarose overlay yielded mengovirus plaques earlier and in greater size and number than overlays of chemically undefined agars with or without enhancers. marked variability in plaque-forming efficacy of commercial agarose preparations was noted. | 1970 | 4320349 |
haemagglutination-inhibition antibodies to encephalomyocarditis virus in queensland cattle. | 1970 | 4317520 | |
studies of the protein subunit of ph-inactivated mengo virus variants. i. polypeptide composition. | 1970 | 4318981 | |
mengovirus rna synthesis in productive and restrictive cell lines. | 1970 | 4318986 | |
influence of blood clearance rates on interferon production and virulence of mengo virus plaque mutants in mice. | 1970 | 4319089 | |
experimental encephalomyocarditis virus infection in calves. | 1970 | 4319465 | |
transfer of interferon-producing macrophages: new approach to viral chemotherapy. | mice were protected from infection with semliki forest virus and encephalomyocarditis virus by the transfer of peritoneal macrophages that were stimulated to produce interferon in vitro by exposure to a nonreplicating virus. this method of therapy was also utilized in animals infected with encephalomy-ocarditis virus after onset of clinical signs. of these animals 40 percent recovered, but only 9 percent of the control group recovered. | 1970 | 4319682 |
tissue-specific factor required for the translation of a mammalian viral rna. | 1970 | 4319843 | |
the structural proteins of mengo virus variants. | 1970 | 4314506 | |
polyacetal carboxylic acids: a new group of antiviral polyanions. | chlorite-oxidized oxypolysaccharides are polyacetal carboxylic acids. they inhibited the cytopathic effect of vesicular stomatitis virus in mouse embryo cell cultures challenged at low input multiplicity. after intraperitoneal injection of these compounds in mice, interferon appeared in the circulation. the compounds also protected mice against lethal mengovirus infection and against the development of experimental pox lesions on the tail. chlorite-oxidized oxyamylose was antiviral only when at ... | 1970 | 4314553 |
antiviral activity of chlorite-oxidized oxyamylose, a polyacetal carboxylic acid. | intraperitoneal injection of chlorite-oxidized oxyamylose (coam) protected mice against mengo, vaccinia, semliki forest, and influenza apr8 viruses. topical administration in the eye of rabbits partially inhibited the development of experimental herpetic keratoconjunctivitis. coam resembled polyacrylic acid in many aspects, but it was markedly less toxic. for systemic administration, the therapeutic index was on the order of magnitude of 1:300 to 1:500. although the in vivo antiviral effect of c ... | 1970 | 4314554 |
synthesis and cleavage of enterovirus polypeptides in mammalian cells. | evidence is presented that the entire enterovirus ribonucleic acid genome is translated into a single giant polypeptide of well over 200,000 daltons molecular weight. this giant protein was detected repeatedly in coxsackievirus b1-infected cells, even in the absence of amino acid analogues. the enzymes which cleave this giant protein into smaller structural and enzymatic proteins accumulate with increasing time after infection. it appears that they are either virus-coded proteolytic enzymes or e ... | 1970 | 4314555 |
[cellular alterations proper to viral infections]. | 1970 | 4315390 | |
studies of the ph inactivation of three variants of mengo encephalomyelitis virus. | 1970 | 4315409 | |
inhibition of synchronized cellular deoxyribonucleic acid synthesis during newcastle disease virus, mengovirus, or reovirus infection. | cultures of l cells were synchronized with respect to deoxyribonucleic acid (dna) synthesis with thymidine and 5-fluoro-2'-deoxyuridine (fudr) and infected with newcastle disease virus (ndv), mengovirus, or reovirus 3. inhibition of incorporation of (3)h-cytidine into the dna of synchronized cells is partially inhibited 2 hr after infection with ndv or mengovirus and nearly completely suppressed 4 hr after infection. with ndv and mengovirus, no evidence was obtained of differences in sensitivity ... | 1970 | 4317111 |
effect of hypobaric hypoxia on mm virus infection. | 1970 | 4317234 | |
physical and chemical studies of mengo virus variants. 3. absorbance--temperature profiles, sedimentation in dextran sulfate gradients, and total-infectious particle ratios. | 1970 | 4315866 | |
retention of functional coding properties by polyribosomes in the x-irradiated mammalian cell. | 1970 | 4317245 | |
effect of persistent fibroma virus infection on susceptibility of cells to other viruses. | shope fibroma virus establishes a persistent cytoplasmic infection in primary (rk) and serially cultivated (drk(3)) rabbit kidney cells which is accompanied by a morphological alteration of the cells. the response of such cells to superinfection by other viruses was compared with that of control cells by determining plaque production and virus yield of superinfecting viruses. it was found that the growth of other poxviruses, myxoma and vaccinia, was greatly inhibited in the fibroma virus-infecte ... | 1970 | 4317346 |
sedimentable and non-sedimentable interfering components in mouse embryo cultures treated with molluscum contagiosum virus. | 1970 | 4313395 | |
[interferon-inducing capacity of double-stranded rna. ii. studies on mengo virus replicatative intermediate]. | 1970 | 4312964 | |
translation of rna from encephalomyocarditis virus in a mammalian cell-free system. | 1970 | 4311932 | |
the step in cellular dna synthesis blocked by newcastle disease or mengovirus infection. | 1970 | 4312372 | |
differential susceptibility to a viral agent in mice housed alone or in groups. | 1970 | 4315920 | |
growth of viruses in organ cultures of intestine. | 1970 | 4316099 | |
ribonucleic acid content of encephalomyocarditis virus. | 1970 | 4313708 | |
particle weight and other biophysical properties of encephalomyocarditis virus. | 1970 | 4313709 | |
the effect of parenteral and oral immunization on encephalomyocarditis infection in mice. | 1970 | 4314148 | |
making proteins in higher cells. | 1970 | 4315547 | |
cytoplasmic methionine transfer rnas from eukaryotes. | 1970 | 4315548 | |
viral myocarditis during pregnancy: encephalomyocarditis virus infection in mice. | 1970 | 4316715 | |
antiviral activity of double stranded rna from a virus isolated from aspergillus foetidus. | 1970 | 4316959 | |
effect of statolon on aerogenic immunization of mice with mengovirus-37a. | 1970 | 4317263 | |
circular dichroism studies on mengo virus variants and their constituent ribonucleates. | 1970 | 4318119 | |
suspected encephalomyocarditis virus infection in pigs. | 1970 | 4318414 | |
encephalomyocarditis virus multiplication in the presence of pyronine. | 1970 | 4318433 | |
[the induction of nonspecific resistance by lysozyme and aristolochia acid in bacterial and viral infections]. | 1970 | 4318514 | |
stimulatory and inhibitory effects of adenovirus and sv40 on various virus-cell systems. | 1970 | 4318579 | |
the growth of viruses in organ-cultures of intestinal epithelium. | 1970 | 4317691 | |
some properties of a new epithelial cell line of human origin. | 1970 | 4317734 | |
jumping on the bandwagon. | 1970 | 4317811 | |
protection of mice against bacterial infection by interferon inducers. | antibacterial effect of known interferon inducers was investigated. intraperitoneal injection of statolon or pyran markedly enhanced the survival of mice challenged with klebsiella pneumoniae. the sparing effect of these two interferon inducers resembled that of bacterial endotoxin. significant protection was obtained when the inducers were administered 24 hr before challenge. treatments given 6 hr before or at the time of infection were ineffective. the persistence of increased resistance of tr ... | 1970 | 16557727 |
circular structures in preparations of the replicative form of encephalomyocarditis virus rna. | 1970 | 11947520 | |
protein synthesis directed by encephalomyocarditis virus rna: properties of a transfer rna-dependent system. | small amounts of encephalomyocarditis virus rna direct a 50-fold increase in amino acid incorporation, in appropriately supplemented ascites tumor cell extracts, under conditions that give rise to authentic viral polypeptides. incorporation in these crude extracts has a novel characteristic, namely, that it is almost entirely dependent upon the addition of exogenous trna. further, this incorporation is restricted in that trna derived from ascites tumor cells or from rat liver permits translation ... | 1971 | 4332253 |
[synthesis of the components of the encephalomyocarditis virus. the rna of polymerase reaction in vitro]. | 1971 | 4332925 | |
cellular dna replication in infections with cytocidal rna viruses. | 1971 | 4332966 | |
encephalomyocarditis viral valvulitis in new-born mouse. | 1971 | 4333311 | |
a comparison of the protective effect against mengo virus infection in mice of interferons induced by polyi:c and mengo virus. | 1971 | 4333910 | |
[the structure of the replicative form of encephlomycarditis virus rna]. | 1971 | 4333526 | |
repair replication of hela cell deoxyribonucleic acid in cells infected with newcastle disease virus or mengovirus or treated with puromycin. | we examined repair replication of hela cell deoxyribonucleic acid (dna) in cells infected with mengovirus or newcastle disease virus or treated with puromycin. cellular dna was damaged by ultraviolet light and then pulse-labeled with (3)h-thymidine. autoradiographic analysis of non-s-phase dna synthesis (repair replication) showed that there was no inhibition of this process at a time when overall cellular dna synthesis was severely inhibited by either virus infection or puromycin treatment. | 1971 | 4331658 |
antiviral activity of tobacco leaf on encephalomyocarditis (emc) virus infection. | 1971 | 4331947 | |
resistance to virus infection during the hyporeactive state of interferon induction. | 1971 | 4330349 | |
system of double infection between vaccinia virus and mengovirus. | when l cells are simultaneously infected with vaccinia virus and mengovirus, double interference in the replication of both viruses is observed. superinfection of vaccinia virus-infected cells by mengovirus during the first 5 hr of infection reduces vaccinia virus yields to between 1 and 3% of controls. the yields of mengovirus are reduced to between 1 and 16% of controls, depending upon the time of superinfection. the replication of vaccinia deoxyribonucleic acid is not inhibited by mengovirus; ... | 1971 | 4330362 |
studies of the protein subunit of ph-inactivated mengo virus variants. ii. physicochemical properties. | 1971 | 4330368 | |
further studies on a purification procedure for encephalomyocarditis virus. | 1971 | 4330790 | |
interferon levels and resistance to viral infection associated with selected interferon inducers. | 1971 | 4331094 | |
formation of small plaques by herpes viruses irradiated with ultraviolet light. | 1971 | 4331109 | |
[antiviral activity of imidazole derivatives. i. inhibition of multiplication of mengovirus in fl cells]. | 1971 | 4329638 | |
[antiviral activity of imidazole derivatives. ii. studies on rna and protein synthesis]. | 1971 | 4329639 | |
duration of resistance to viral infection following administration of interferon inducers. | 1971 | 4328255 | |
host-cell repair of vaccinia virus and of double stranded rna of encephalomyocarditis virus. | 1971 | 4328801 | |
the relationship between serum interferon and an inhibitor of mouse haemopoietic colonies in vitro. | 1971 | 4329930 | |
[demonstration of the mengo virus antigen in the mouse brain by help of the immunofluorescence technique]. | 1971 | 4327126 | |
effect of antilymphocytic serum on circulating interferon in mice as a function of the inducer. | 1971 | 4325471 | |
immunofluorescent studies on the effect of antiviral substances on virus multiplication. ii. determination of fluorescence intensity in mengo virus infected l cells treated with beta-2-dl-thienylalanine. | 1971 | 4325975 | |
immunofluorescent studies on the effect of antiviral substances on virus multiplication. 3. effect of actidione on the multiplication of mengo virus. | 1971 | 4325976 | |
interferon in mouse brain. | 1971 | 4326390 | |
diabetes mellitus-like syndrome in mice infected with encephalomyocarditis virus. | 1971 | 4323473 | |
encephalomyocarditis infection of the newborn mouse myocardium. an electron microscopic study. | 1971 | 4321486 | |
cellular changes attending mengovirus-induced cytolysis of mouse l-cells. | 1971 | 4108194 | |
effects of phenylalanine analogues on virus multiplication and protein synthesis in a cell-free system. | 1971 | 4397338 | |
[synthesis of virus-specific proteins in cells infected by the encephalomyocarditis virus]. | 1971 | 5103259 | |
early myocardial lesions in encephalomyocarditis (emc) virus infected mice. | 1971 | 4334293 | |
mural and valvular endocarditis of mice infected with encephalomyocarditis (emc) virus. | 1971 | 4336178 | |
interferon-inducing characteristics of mm virus. | interferon induction by mm virus in mice and in l cells was studied. in mice the virus readily induced interferon. the time of appearance was dose-dependent. a large virus dose induced interferon by 4 hr, whereas a small dose resulted in interferon production which paralleled virus replication 24 hr after infection. in l cells the interferon-inducing capacity of the virus was rapidly destroyed by ultraviolet light irradiation. heating (56 c) of the virus, on the other hand, greatly increased its ... | 1971 | 4324191 |