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does insulin dependent diabetes mellitus have a viral etiology?clinical, epidemiological, and experimental observations suggest that common viruses may play an etiologic role in at least some cases of insulin dependent diabetes mellitus. the evidence is summarized and critically assessed in this presentation.1979223962
molecular approach to the epidemiology of swine vesicular disease: correlation of variation in the virus structural polypeptides with serological properties.variation has been observed in the structural polypeptides of swine vesicular disease viruses isolated from the united kingdom and hong kong. despite the limited number of isolates examined, several distinct polypeptide patterns were obtained when the virus structural proteins were examined by polyacrylamide gel electrophoresis. isolates from outbreaks in the united kingdom which were known to be connected gave the same polypeptide pattern, whereas viruses with different polypeptide patterns cou ...1979223980
fatal hand-foot-and-mouth disease in an adult caused by coxsackievirus 47. 1979224221
clinical features of acute coxsackie b viral myocarditis.clinical features of 11 patients of acute coxsackie b viral myocarditis diagnosed by neutralizing antibody titers were reported. all patients had a flu-like symptom and 8 patients had fever. initial cardiac manifestations were congestive heart failure in 9 patients, and syncopal attack in 4 patients. electrocardiographic abnormalities frequently observed were non-specific st-t changes, low voltage, and intraventricular conduction, disturbances including 4 patients of complete a-v block due to tr ...1979224222
[clinical analysis of 78 cases of viral myocarditis]. 1979224241
[viral infection in the etiology of juvenile diabetes mellitus]. 1979224376
[observations on the isolation of polio in 2 cases]. 1978224540
stability of three animal viruses in thyroid tissue from infected swine. 1979224564
virus induced diabetes and the immune system. ii -- evidence for an immune pathogenesis of the acute phase of diabetes.the infection of normal dba2 and balb/c nu/ + mice with 2 x 10(2,6) tcid50 of the m variant of the emc virus induced pathological mean glucose values of 426 +/- 99 mg/100 ml in dba2 mice and 292 +/- 130 mg/100 ml in balb/c nu/ + mice on day five following infection. as diabetic animals died afterwards, mean glucose values decreased in the surviving animals on day seven and fourteen. the infected immunodeficient balb/c nu/nu mice with thymus aplasia did not show abnormal mean glucose values or hi ...1979224966
second-step concentration of viruses in drinking and surface waters using polyethylene glycol hydroextraction.in our laboratory, virus adsorbed to talc--celite layers is eluted with 100 ml of 10% fetal calf serum (fcs) in normal saline (ph 9.0). a further 10-fold reduction in the volume of the eluate was necessary before its inoculation into cell cultures. a 100-ml volume of an experimentally contaminated sample was placed in a dialysis sac and hydroextracted overnight (4 degrees c) with polyethylene glycol (peg) 6000. the viscous material remaining in the sac was resuspended in 10 ml of earle's balance ...1979224994
[therapeutic and diagnostic problems of generalized acute suppurative periodontitis marginalis profunda].generalized periodontal abscesses with considerable increase in the volume and sensitivity of the gingiva, tooth loosening, and malaise accompanied by fever and weight loss were observed in 22 of 35 patients studied. the symptoms developed after antibiotic treatment for another disease. local therapeutic measures alone were successful. success was obtained only after institution of directed antibiotic therapy.1979225154
selective polymyositis inducted by coxsackievirus b1 in mice.a high-passage laboratory strain of coxsackievirus b1 produced a unique myositis that predominantly and profoundly affected hip extensors and, to a lesser extent, hindquarter knee flexors when inoculated into a strain of random-bred newborn mice of swiss origin (coh mice). the effect was not observed in balb/c or c3h mice similarly inoculated. in addition to the differences in susceptibility of the mouse strains, it was found that six different low-passage "field" isolates of coxsackie-virus b1 ...1979225392
studies of the replication of a bovine enterovirus rna.replicative intermediate (ri), replicative form (rf) and single-stranded (ss) rna have been isolated from bhk cells infected with a bovine enterovirus by salt precipitation and gel filtration techniques. kinetic experiments showed that at no time up to 16 h post-infection (p.i.) did the amount of rf exceed that of ri or ss rna. electrophoresis of rf on 1.5% polyacrylamide-agarose gels showed that at least three species of double-stranded rna were present, one of which was associated with an acce ...1979225421
properties of coxsackievirus b3 variants which are amyocarditic or myocarditic for mice.inoculation of adolescent cd-1 mice with one variant of coxsackievirus b3 (cvb3m) results in induction of readily observable myocardial lesions, whereas inoculation of siblings with a second variant (cvb3o) results in little or no myocarditis. these variants could not be distinquished from each other on the basis of replication properties in hela cells or cardiac tissues in vivo, sensitivity to human interferon in hela cells, induction of interferon in the mouse, generation of detectable levels ...1979225441
[sensitivity of transplantable cell cultures to group b coxsackie viruses when using bentonite]. 1979225645
the formation of complexes between polynucleotides, carboxymethylcellulose and polylysine which are anti-viral in mice without inducing interferon. 1979225654
effects of viral exposure of the two-cell mouse embryo on cleavage and blastocyst formation in vitro.the effect of viral exposure of two-cell mouse embryos on their capacity to undergo subsequent cleavage and blastocyst formation in vitro was determined. exposure to coxsackie viruses b-4 and b-6, reovirus type 2, influenza virus type a, mouse cytomegalovirus, adenovirus type 5, and mouse adenovirus resulted in statistically significant inhibition of blastocyst formation. development in vitro was unaffected by exposure to echo virus type 11, attenuated poliomyelitis virus type 2, parainfluenza v ...1979225719
glutaraldehyde inactivation of exotic animal viruses in swine heart tissue.glutaraldehyde, 0.2%, in a 1:100 (wt/vol) ratio, inactivated four animal viruses (foot-and-mouth disease, swine vesicular disease, african swine fever, hog cholera) in swine heart tissues during 11-day exposures at 22 to 26 degrees c.1979225989
virucidal activity of some quaternary ammonium compounds.four different quaternary ammonium compounds were tested by microtechniques for evaluating their activity against the type species of six viral groups very frequently involved in human and animal pathology. three disinfectants showed good activity against five of the representative viruses under test, while the fourth proved less effective. poliovirus type 1 was found to be completely resistant.1978226100
altered immune reactivity in encephalomyocarditis-m variant (emc-m)-induced diabetes in mice.approximately 50% of dba/2j male mice infected with emc-m develop glycosuria with suppressed immune responsiveness to the mitogens pha, con a and pwm. the greatest degree of suppression was noted with con a treated cultures. in vivo treatment with levamisole, a known t cell stimulant, especially increased the response to con a but exacerbated the diabetogenic state as reflected by increased occurrence of glycosuria. virus infected mice, given anti-lymphocyte serum (als), showed marked ameliorati ...1979226473
in vivo and in vitro studies on temperature-sensitive mutants of swine vesicular disease virus.two temperature-sensitive mutants of the ukg 27/72 strain of swine vesicular disease virus were isolated in tissue culture and a third was derived following adaptation in mice. all three were found to have similar growth restrictive temperatures, but varied considerably in their virulence when administered to pigs. the route of inoculation appeared to exert a considerable influence on the apparent degree of attenuation, the antibody titre engendered and the transmission of disease to pigs held i ...1979226626
trichomonas vaginalis resistance to mengo virus infection.we have investigated the susceptibility of trichomonas vaginalis to mengo virus infection by comparing the outcome of mengo virus or purified mengo virus rna infection in t. vaginalis and in ccl-1 mouse fibroblasts. while the adsorption and entry of mengo virus into t. vaginalis occurred in the same manner as in fibroblasts, the uncoating was much slower. in addition, mengo virus infection of t. vaginalis displayed no eclipse nor any subsequent production of infectious virus. purified rna failed ...1979226694
[viral diseases (author's transl)]. 1979226759
[viruses as originators of acute gastroenteritis]. 1979227181
[properties and methods of use of peracetic acid in medical practice]. 1979227182
virus-induced diabetes mellitus: infection of mice with variants of encephalomyocarditis virus, coxsackievirus b4, and reovirus type 3. 1979227239
[clinical and etiological study of viral conjunctivitis during five years, 1974--1978, sapporo, japan (author's transl)]. 1979227255
the effect of water from the bay of gdaƄsk on preservation of contagious properties of the viruses coxsackie b type 3 and echo type 1. 1979227500
prenatal influence on immunocompetence of the neonate. 1979227826
coxsackieviruses and adult human cardiac illness in egypt. 1978227950
effect of antiviral lipids, heat, and freezing on the activity of viruses in human milk.semliki forest virus (sfv), herpes simplex virus type 1 (hsv-1), coxsackievirus b4, and cytomegalovirus (cmv) were added to human milk, which was then subjected to treatments that approximated those required for the decontamination or storage of milk. boiling was the only treatment that eliminated these viruses from the milk. pasteurization (at 62.5 c for 30 min) did destroy cmv, but the other viruses could still be detected. all of the viruses except hsv-1 were detectable after the contaminated ...1979227969
occurrence of infection with group b coxsackievirus in rheumatic and nonrheumatic filipino children.the pathogenesis of rheumatic fever has been linked to various immune mechanisms involving streptococcal antibodies and heart tissue antigens. latent myocarditis due to group b coxsackievirus has also been considered as a possible conditioning factor. the validity of the role of infection with group b coxsackievirus in rheumatic fever was tested by determining the incidence of type-specific neutralizing antibodies in sera of filipino children. analysis of the results by means of a normal z-test ...1979227971
protection of mice against infection with wild-type mengo virus and an interferon sensitive mutant (is-1) by polynucleotides and interferons.single-stranded polynucleotide preparations [trna, poly(ri) plus poly(ho5c)-copolymer] which protect mice against picornavirus infections without inducing interferon, protected mice equally against infection with an interferon-sensitive mutant (is-1) of mengo virus and with wild-type virus (is+). poly(ri) . poly(rc), and mouse macrophage interferon [i.e. serum from mice treated with poly(ri) . poly(rc)] protected mice equally against infections with the two viruses, but fibroblast interferon pro ...1979227997
[coxsackie viruses and diabetes mellitus]. 1978228385
coxsackie b viruses and heart muscle disease in nigerian adults.in 44 nigerians with heart muscle disease, the percentage of patients who had a fourfold rise or fall to at least one of the coxsackie b viruses was greater than controls. patients with heart muscle disease also had significantly higher levels of antibody titres. antibodies to coxsackie viruses b2, b3 and b6 were more frequent in their sera than in controls. while these results do not prove a coxsackie b viral aetiology it is concluded that these viruses could be the cause of cardiac damage and ...1979228451
[does an autoimmune process play a role in the pathogenesis of obstructive cardiomyopathy? (author's transl)]. 1979228507
[microbial emission, immission and changes in the germ count in the cooling water during operation of wet cooling towers ii. communication: measuring methods, emission values and changes in the germ count in the cooling system (author's transl)].the second in the series "microbial emission, immission and changes in the germ count in the cooling water of wet cooling towers" describes measuring methods and results of the measurements for determining the emission values and the changes in the germ count in the cooling system. the content of colony-forming units (kbe) in the cooling water varied widely, depending on the germ content of the surface water and the preparation of the cooling water (filtration, chemical conditioning). in summer ...1979228514
indication of viruses in shellfish growing waters. 1979228560
failure of indicator bacteria to reflect the occurrence of enteroviruses in marine waters.the results of several studies conducted along the upper texas gulf coast, where a substantial amount of quantitative virological data were collected, are compared to bacteriological indicators and other environmental factors on a statistical basis. variables common to all these studies were anlayzed by multivariate regression. although multivariate analysis indicated that the number of viruses detected in water was related to rainfall, salinity, and total coliforms in the water, the amount of v ...1979228561
[anti-coxsackievirus activity in vitro on culture filtrates of agaricales (author's transl)]. 1979228584
the to strains of theiler's viruses cause "slow virus-like" infections in mice.intracerebral inoculation of mice with tissue culture-adapted to strains of theiler's mouse encephalomyelitis viruses results in a clinical disease consisting of spastic paralysis due to demyelination after a lengthy incubation period. thus, in effect, these ordinary picornaviruses are capable of causing a slow infection in their natural host, the mouse. in addition, through the use of tissue culture-adapted virus stocks, virus content in mouse tissues now can be accurately quantified by standar ...1979228588
coxsackievirus type a16 infection in a neonate. 1979228613
enterovirus 71 isolated from cases of epidemic poliomyelitis-like disease in bulgaria.virological and serological studies of an epidemic disease in bulgaria, 1975, were carried out. epidemiologically, clinically and pathomorphologically, the disease simulated almost all known forms of poliomyelitis, acute stem encephalitis, encephalomyocarditis and aseptic meningitis. the studies completely rules out the participation of polioviruses and provided comprehensive evidence for the etiological role of a peculiar enterovirus subsequently identified as enterovirus (ev) type 71 known in ...1979228639
investigation of physicochemical properties of bulgarian strain 258 of enterovirus type 71. brief report.in the present report some general physicochemical properties and rna characteristics of strain 258 of enterovirus (ev) 71, isolated in 1975 from cases of poliomyelitis-like disease in bulgaria (1), are described. it is concluded, that the features of the virus are consistent with the previous identification, based on biological studies, of this virus strain as a member of enterovirus subgroup of picornaviridae family.1979228641
pathogenicity of mengo virus to mice. iii. potentiation of infection by immunosuppressants.mengo virus has been described to cause, in dependence on the virus dose, lethal panencephalomyelitis and exocrine pancreatitis in mice after i.p. inoculation. two immunosuppressive agents, cyclophosphamide and 1,3-bis(piperidinomethyl)-5-ethyl-5-phenyl-barbituric acid (zimet 176/68), were shown to potentiate mengo virus infection as demonstrated by histopathology and enhanced mortality. organotropism of mengo virus did not change under the drug treatment. however, the histological lesions in br ...1979228963
factors involved in enzyme-linked immunoassay of viruses and evaluation of the method for identification of enteroviruses.a quantitative enzyme-linked immunosorbent assay was used for identification of selected enteroviruses: poliovirus type 1, echovirus type 6, coxsackievirus a type 9, and coxsackievirus b types 1 through 6. partially purified viral antigens or virus-specific antibodies were adsorbed to polystyrene spectrophotometer cuvettes, which permitted the assays to be reported and compared in terms of enzyme units specifically reacting. both the adsorbed antigen and the adsorbed antibody methods were approx ...1979229122
[the most important problems of the etiology and clinical aspects of primary myocardial diseases in children]. 1979229296
perinatal infection. 1979229446
[virological diagnosis of enteroviral diseases].68 human enteroviruses are responsible for many acute viral diseases. an economic diagnostic procedure is discussed and documented by the author's own findings. virus isolation is regarded as the method of choice, for epidemiological reasons and in view of the fact that enteroviruses are often isolated within a few days.1979229546
[effect of a viral infection on the cellular chromosome apparatus of mice in vitro and in vivo against a background of hydrocortisone action].a cytogenetic investigation of murine bone marrow after hydrocortison injection has been made. high doses of hormone (50 mg/kg) provoke deteriorations in bone marrow both in the structure and in the chromosome number. a dose of 5 mg/kg has no such effect. the koksak a13 virus does not induce cytogenetic deteriorations in mice, however, it is able to produce a big mutagenic effect on the hydrocortison background. the vaccine strain of measles virus -- leningrad-16 -- also increases its mutagenic ...1979229597
pathogenesis of swine vesicular disease in pigs.pigs exposed to swine vesicular disease virus developed vesicular lesions by postinoculation day 2. lesions first appeared on the coronary band and then on the dewclaw, tongue, snout, lips, and bulbs of the heels. the onset of viremia coincided with febrile response and the appearance of vesicles. virus was isolated from the nasal discharge, esophageal-pharyngeal fluid, and feces as early as postinoculation day 1. greater amounts of virus were isolated from samples collected during the first wee ...1979229744
bioaccumulation and depuration of enteroviruses by the soft-shelled clam, mya arenaria.low levels of feces-associated natural virus, simulating virus numbers estimated to exist in moderately polluted shellfish-growing waters, were used to evaluate the effectiveness of depuration as a virus depletion procedure in soft-shell clams. depuration effectiveness depended upon the numbers of virus bioaccumulated and whether virus was solids associated. virus uptake was greatest when viruses were solids associated and pollution levels were equivalent or greater than those likely to be found ...1979229766
survey of human enterovirus occurrence in fresh and marine surface waters on long island.a variety of surface water systems, including a lake, a creek, and two marine embayments, were analyzed on a monthly basis for indigenous human enteroviruses and coliform bacteria. findings are discussed in terms of the probable pollution sources to each system and their relationship to data from previous studies.1979229767
lead-cadmium interaction: effects on viral-induced mortality and tissue residues in mice.simultaneous exposure to lead and cadmium is highly probable due to common environmental sources of exposure. mice were exposed simultaneously for 10 wek to lead and cadmium and effects were observed on accumulation of the metals in tissues and susceptibility to viral challenge. the incidence of viral-induced mortality was enhanced in all groups of mice exposed to lead and suppressed in groups of mice treated with cadmium. mice exposed to both lead and cadmium had mortality rates intermediate to ...1979229776
clones of cells from a human embryo lung: their growth and susceptibility to respiratory viruses.colonies of cells were obtained from human fetal lung tissue and exposed to recently isolated respiratory viruses. there was a considerable variation in the number of rounded cells found in different colonies exposed to rhinovirus types 2 and 9 (rv2 and 9), human coronavirus 229e (hcv), adenovirus type 3 (ad3) and respiratory syncytial virus (rsv). smaller colonies had more rounded cells than larger colonies. clones were established from 9 out of 11 colonies. they varied in their rate of growth ...1979229795
rhinoviruses: kinetics of ultraviolet inactivation and effects of uv and heat on immunogenicity.the kinetics of ultraviolet inactivation for two human rhinoviruses and poliovirus were compared. no major differences in the rates of ultraviolet inactivation were detectable. all viral preparations inactivated by ultraviolet irradiation induced neutralizing antibody in guinea pigs. in contrast, when guinea pigs were immunized with a heat inactivated rhinovirus preparation, little or no neutralizing antibody was elicited. immune electron microscopy of the heated rhinovirus preparations revealed ...1979229797
classification of porcine enteroviruses by antigenic analysis and cytopathic effects in tissue culture: description of 3 new serotypes.porcine enteroviruses isolated in the united kingdom between 1972 and 1976 were compared with the 8 serotypes previously described and with human coxsackie b virus types 1 to 6 for ability to grow in different cell lines. this allowed the classification of all strains into 3 broad groups according to type of cytopathic effect in ibrs-2 cells and further subdivision on the basis of production of cytopathic effect in bhk 21, hela and vero cells. none of the porcine enterovirus strains was neutrali ...1979229804
[method for isolation of enteroviruses from edible mollusca].a method for recovery of poliovirus from experimentally inoculated mussels has been evaluated. the method, based on adsorption-elution-acid precipitation of virus particles, allows a recovery of more than 93% of the added virus.1979229885
viruses and virus diseases of marine mammals.poxvirus and several serotypes of calicivirus cause recognizable disease in marine mammals. pox lesions in pinnipeds are raised and proliferative and are seen most frequently after confinement in captivity. in cetaceans, a poxvirus is associated with a much more benign and chronic lesion called a "tattoo." numerous caliciviruses of differing antigenic types have been isolated from vesicular lesions and aborted fetuses of northern fur seals and california sea lions as well as from clinically norm ...1979230170
absence of significant antiviral effects of beta-gamma-methylene gtp on encephalomyocarditis virus infection of l cells and mice.the protein synthesis inhibitor beta-gamma-methylene guanosine triphosphate (gpp-ch2p) is shown here to be ineffective as a 'leaky membrane' antiviral agent against encephalomyocarditis virus infection of l cells and mice. studies with gppch2p in encephalomyocarditis virus-infected l cells indicate that the cells only become permeable to the inhibitor late in infection because the compound significantly inhibits protein synthesis only when added at 4 h p.i. at this time 50 to 70% of the new infe ...1979230305
the nature of virus-like particles in the paraxial muscles of idiopathic scoliosis.virus-like particles (vlp) have been identified by electronmicroscopy in the skeletal muscles (paraxials) of six cases of idiopathic scoliosis. these particles closely resembled vlp reported in the skeletal muscles in other conditions, e.g. reye's syndrome, polymyositis, malignant hyperthermia, and chronic myopathy. we have shown by specific staining that these structures are composed of glycogen in a crystalline form. using coxsackie b infected tissue culture cells as a control we have shown th ...1979230331
secondary myocardial disease. virus myocarditis and cardiomyopathy.in an attempt to prove the hypothesis that virus myocarditis may be a cause of idiopathic cardiomyopathy, clinical and experimental studies were performed. eleven patients with a presumptive or proven diagnosis of virus myocarditis were followed for one and a half to 13 years after the acute illness. one patient died in the acute stage, six recovered completely and one continued to have bifascicular block without subjective symptoms. three patients had exertional dyspnea, cardiomegaly and an abn ...1979230367
experimental study of virus myocarditis in culture.in this present paper, the authors would like to present here two points of results from the experimental study concerning virus myocarditis in culture. one is the direct delicate features of heart cells affected with coxsackie b3 (cox. b3) virus viewed through both light microscope and electron microscope. the other is the fact that marked proliferation of fibroblastic cells take place to replace the heart cells impaired by the virus suggesting to us the possibility of one of the genesisses, re ...1979230368
the role of coxsackie b viruses in heart disease in new zealand.sera from 622 patients received in a 20-month period were examined for coxsackie b neutralising antibody to serotypes 1--6. two hundred and thirty-four of the total 622 were patients with a cardiac symptomatology, and 388 formed a comparable group of non-cardiac cases. there were 141 (60 percent) seropositive patients in the cardiac group, 34 percent and 29 percent of which respectively had antibody to b4 and b2. the clinical data provided on these 141 patients indicated that 33 (23 percent) had ...1979230431
[clinical and enterovirological studies of children with nonrheumatic myocarditis]. 1979230445
[paralytic poliomyelitis and poliomyelitis-like diseases in children]. 1979230451
[enteroviruses (author's transl)]. 1979230470
[role of coxsackie group b viral infection in nonrheumatic myocarditis and recurrent rheumocarditis]. 1979230637
[physicochemical properties of the teschen disease virus].the physical stability of teschen disease virus (tdv) was tested. it was found that 8 m urea at 37 degrees c and 0.5% tween-20 for 1-2 hours destroyed tdv with formation of morphologically distinct subunits. the morphology of tdv virions and its subunits formed under the effect of urea and tween-20 was studied. sedimentation constant (120 s) and the polypeptide composition of tdv were determined. in tdv, major polypeptides (vp1 less than or equal to 4) and minor polypeptides (vp1m and vp2m) were ...1979230644
antiviral effects of a microbial growth inhibitory factor. 1979230676
a seroepizootiologic study of five viruses in a swine-evaluation station.this serologic study was done to gain information on the spread, maintenance, and effect upon performance of five porcine viruses. blood samples were taken from two groups of 8- to 11-week-old pigs from a large number of indiana swine herds in a performance-testing station 1 week after entry, 7 weeks after entry (one group only), and at slaughter. the sera were tested by indirect fluorescent antibody tests for antibodies to transmissible gastroenteritis virus (tgev), swine influenza virus (siv), ...1979230762
survival of enteric viruses under natural conditions in a subarctic river.the survival of enteric viruses was studied in the vicinity of fairbanks, alaska at selected stations along a 317-km section of the tanana river. this section was located downstream from all known domestic wastewater sources and was effectively sealed by a total ice cover. the mean flow time through the region was 7.1 days, during which initial viral population showed a relative survival rate of 34%. the tracing of native viruses at such great distances in the complete absence of other point and ...1979230786
in vitro isolation, propagation, and characterization of duck hepatitis virus type iii.the in vitro isolation, propagation, and characterization of duck hepatitis virus type iii (dhv-iii), is described. this virus, which is serologically distinct from the classical (type i) dhv, replicated in liver and kidney cell cultures of duck origin. replication was limited in chicken and quail kidney and duck embryo fibroblast cultures. it did not replicate in a variety of other cell cultures of avian or mammalian origin. the virus was grown successfully in embryonating eggs of ducks, but no ...1979230809
virus detection in soils: a comparison of four recovery methods.among nine eluents tested, 0.5% (w/v) isoelectric casein at ph 9.0 and 0.5% (w/v) non-fat dry milk (ph 9.0) were the most efficient in eluting poliovirus type 1 (sabin) from eustis fine sand. however, no significant difference was found between the overall (elution followed by concentration) virus recoveries by non-fat dry milk, isoelectric casein, beef extract, and glycine-edta methods. high overall recovery (75%) of low input (200 pfu) of viruses from 100 g of soil was achieved by the isoelect ...1979230890
epidemiological, clinical, and pathomorphological characteristics of epidemic poliomyelitis-like disease caused by enterovirus 71.in may-september, 1975, an outbreak of epidemic disease clinically and pathomorphologically simulating nearly all known forms of poliomyelitis occurred predominantly among young infants in bulgaria. most cases presented benign aseptic meningitis, sometimes with a short period of general cerebra- symptoms. paralytic forms, such as bulbar polioencephalitis, anterior poliomyelitis, isolated pareses of the facial nerve, occasional cases of encephalomyocarditis, etc., were observed in about 21% of al ...1979231067
[intestinal viruses in the offshore zone of seas]. 1979231186
an outbreak of diarrhea in school children associated with coxsackie virus b-3 infection. 1979231430
myocardial uptake of technetium-99m stannous pyrophosphate in experimental viral myopericarditis.distribution of technetium-99m stannous pyrophosphate was studied in mice with experimentally induced viral myopericarditis. myocardial and bone uptakes of tc-ppi were compared in 55 mice inoculated with coxsackievirus b3 (nancy strain). the myocardium-to-bone uptake ratio in 33 mice with myopericarditis was increased to a greater extent than that seen in 22 mice without myopericarditis (p less than 0.001). in the severely involved heart, the uptake per gram exceeded that in the bone. myocardial ...1979231641
experimental infection in pigs with encephalomyocarditis virus. 1979231750
[persistent non polio enterovirus infections associated with glomerulonephritis. 9 cases (author's transl)].all patients are excreting the virus in urines and in 4 cases in stools. the virus has also been isolated from the blood. these cases focused on the possible role of enteroviruses as causal agents for the glomerulonephritis.1979231760
preliminary report on an unidentified virus from infantile myocarditis.a preliminary report on an unidentified virus from two cases of infantile myocarditis is presented. the virus isolated from two separate occasions showed characteristics of an enterovirus. the significance of this virus in its association with infantile myocarditis requires further investigation.1979231842
enterovirus diseases with neurological determinations in adults. clinical and virological study.enteroviruses--4 polio, 30 coxsackie and 20 echovirus strains--were isolated from 54 patients with neurologic disease. in 29 cases (53.7%) viruses were isolated from the csf, blood clot and nerve tissue homogenates. the correlation of the complex clinical data and the localisation of the lesions in the cns demonstrate the involvement of cranial nerves, of the long bulbar motor pyramidal and extra-pyramidal tracts, of the reticular formation, a.o. these aspects are in accordance with the localisa ...1979231861
viral heat resistance and infectious ribonucleic acid.high-titer suspensions of poliovirus 1 and coxsackievirus b-2 were shown to contain a heat-resistant fraction when heated for 65 min at temperature ranging from 56 to 70 degrees c. the addition of ribonuclease to the heated suspensions eliminated plaque production in the cell cultures, indicating that the resistant fraction was infectious ribonucleic acid that had been liberated from ruptured viruses during the heating process.1979231935
adsorption of enteroviruses to soil cores and their subsequent elution by artificial rainwater.the adsorption and elution of a variety of human enteroviruses in a highly permeable, sandy soil was studied by using cores (43 by 125 mm) collected from an operating recharge basin on long island. viruses studied included field and reference strains of polioviruses types 1 and 3 and reference strains of coxsackie virus b3 and echovirus types 1 and 6. viruses suspended in treated sewage effluent were allowed to percolate through soil cores, and the filtrate was assayed for unadsorbed viruses. to ...1979231936
procedure for the recovery of airborne human enteric viruses during spray irrigation of treated wastewater.because of the relatively low number of indigenous enteric viruses recovered from secondary wastewater effluents, their presence in air (aerosols) as a result of wastewater spray irrigation requires extensive sampling. methodology to allow the recovery of indigenous enteroviruses from aerosols generated at an operational wastewater irrigation site was tested under both laboratory and field conditions.1979231937
polioviruses and other enteroviruses in urban sewage from laval (canada): presence of non-vaccinal strains of poliovirus.during a 13-month period (august 1, 1977-august 31, 1978) 55 samples of 2-4 l of raw sewage from an urban residential area were collected and studied for the presence of human enteroviruses. viruses were recovered from 47 (90.5%) of the samples. of the 201 viral isolates propagated, 180 (89.5%) were identified by the serum neutralization test as poliovirus types 1,2, or 3; 16 (8%) were identified as coxsackie b viruses; and 5 (2.5%) could not be identified by the methods used. while all poliovir ...1979232002
viruses in soil systems. 1979232033
type 1 diabetes and coxsackie virus infection.the role played by viruses in the aetiopathogenesis of type 1 diabetes mellitus has been studied by several authors; in particular the importance of coxsackie virus b4 infection has been stated by some authors and not confirmed by others. 43 diabetic children were studied at the time of the diagnosis of the disease. no viruses could be isolated from stools; the titres of anti-coxsackie viruses b1 to 6 complement fixing antibodies and anti-coxsackie virus b4 neutralizing antibodies, compared to c ...1979232095
[enteroviruses in cases of lymphocytic meningitis in warsaw during 1963-1976]. 1979232284
enhancement of the antiviral activity of pyrimidine derivatives against mengovirus by visible light.eleven pyrimido-pyrimidine derivatives, seven with significant antiviral activity against mengovirus, five against coxsackie b1 virus and four antiviral negative compounds were tested for their photosensitizing ability. all seven compounds with antiviral activity in vitro showed an enhanced antiviral action against mengovirus under irradiation with visible light, a fact that may be caused by photodynamic processes. it was tried to correlate the oxidation potentials of sensitizers with their phot ...1979232339
[detection of enteroviruses by a concentration on glass powder in a liquid bed from samples of 500 liters of surface water]. 1979232421
[viral antibodies in juvenile diabetes (author's transl)]. 1977232559
[distribution of enteroviruses other than polioviruses in the years 1974-1977, (2nd part) (author's transl)]. 1979232673
[application of immune adherence hemagglutination test for typing of enteroviruses (author's transl)]. 1979233054
[hygienic status of small streams on the periphery of rome. iii. research on pathogenic microorganisms]. 1979233380
[hemolytic-uremic syndrome in adults]. 1979233397
duck virus hepatitis: serial passage of attenuated virus in ducklings.the safety of three attenuated virus vaccines of proven efficacy against duck virus hepatitis was assessed by controlled laboratory studies which involved the serial transmission of the virus through groups of two-day-old ducklings known to be susceptible to the disease. each vaccine was initially derived from a different source. enhancement of virulence which resulted in deaths from the disease in test groups of ducklings occurred in each instance.1979233456
[isolation of enterovirus 70 during an outbreak of acute hemorrhagic conjunctivitis in algeria in 1973].the enterovirus 70 was isolated in algeria in 1973 during an outbreak of acute hemorrhagic conjunctivitis. the main epidemiological features were similar to those previously described in other countries: involvement of the adults especially, mainly those living in communities, irrelevance of the different socio-economical levels of the population. the spring waters may have played a role in the transmission of the disease. the virological study draws the attention on the optimal conditions for t ...1977233461
[isolation and identification of the virus from acute hemorrhagic conjunctivitis in shanghai (author's transl)]. 1979233651
successful treatment of viral-induced diabetes mellitus by islet transplantation. 1978233832
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