Publications

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the effect of altering metabolic rate on the mortality and incubation time of rabies. 19685655650
the present and future in rabies research. 19685666563
removal of encephalitogenicity from extracts of normal rabbit central nervous system by treatment with fluorocarbon. 19685668422
the largest rabies-specific antigen in extracts of infected suckling mouse brains. 19685675580
[the phenomenon of hemadsorption induced by street rabies virus adapted to tissue culture]. 19685686853
one-year immunity in dogs vaccinated with high egg-passage rabies virus grown on established dog kidney cell line. 19685690255
influence of statolon-induced interferon on rabies virus infection in mice. 19685690788
failure to demonstrate a relationship between scrapie and production of interferon in mice. 19685691075
experimental infection of golden hamster with hógyes' fixed strain of rabies virus. 19705501614
treatment of controlled pore glass with poly(ethylene oxide) to prevent adsorption of rabies virus. 19715551919
19 s neutralizing antibody produced in guinea pigs by rabies virus. 19685712546
[sensitivity of some laboratory animals to rabies fixed virus of the sassari strain and to the avianized variants]. 19685716645
[rapid changes of the pathogenicity for the adult mouse of a special avianized variant of rabies fixed virus of the sassari strain]. 19685716646
["in vitro" neutralization of rabies virus by tissues of guinea pigs recovered from infectious rabies]. 19675607711
[considerations on the biology of rabies]. 19685730085
[effect of 1-amino adamantane on reproduction of fixed rabies virus in tissue culture]. 19685733228
[study of the kinetics of rabies virus in intracerebrally inoculated mice]. 19685746277
immune lysis of rabies virus-infected cells. 19685749193
propagation of rabies virus strains in chick embryo tissue culture. 19685753954
purification and partial chemical analysis of rabies virus of tissue culture origin. 19685753955
[alarm against rabies]. 19685754109
changes in the central nervous system after experimental rabies infection and immunization. 1. an electroencephalographic study. 19685728275
a trial to develop a purified antirabies vaccine. 19685759963
[experiments in dogs vaccinated against rabies with virulin a freeze dried modified live vaccine made from rabies virus strain flury lep]. 19685692802
protracted survival of a rabies-infected insectivorous bat after infective bite. 19695764199
a contribution to the knowledge of direct peripheral communication with the central nervous system using a strictly neurotropic rabies virus as a model. 19695770639
the time for which rabies virus can survive locally before its introduction into the central nervous system. 19695770640
rabiesvirus neuronitis. 19695774142
viral subunits for rabies vaccination. 19695775839
immunogenicity of concentrated and purified rabies vaccine of tissue culture origin. 19695791793
[formation and effect of interferon in experimental infections with fixed rabies virus]. 19685708930
[serologic response of vaccinated persons against rabies using fuenzalida type vaccine]. 19695802753
[infection with food-borne rabies virus in experimental conditions]. 19695803035
biochemical and biophysical studies on the nucleocapsid and on the rna of rabies virus. 19695803947
use of synthetic media for the cultivation of rabies virus in tissue culture. 19685760882
sinus worm skrjabingylus spp. (nematoda: pseudaliidae) from rabid skunks (mephitis mephitis) in california. 19695815929
[pathology of the experimental rabies encephalitis with fixed virus in cats]. 19695821312
[experimental studies on rabies in ethiopia]. 19655827406
[on the problem of transmission of the rabies virus by bloodsucking ectoparasites]. 19655832256
[study of the fixed rabic virus cultivated on various cells of canine origin (louis pasteur strain)]. 19655838638
hemagglutination by rabies virus.goose erythrocytes were agglutinated by five strains of rabies virus grown in monolayer cell cultures at ph 6.4 and at 0 to 4 c. hemagglutination was not affected by the cell type in which the virus was grown. prerequisites for occurrence of hemagglutination are absence of hemagglutination inhibitors (such as those contained in bovine serum) and a relatively high virus concentration (> 10(6) plaque-forming units of virus per ml). "soluble" hemagglutinin was not present in crude preparations of e ...19685754504
[contribution to the disinfection of fixed rabies virus with chemicals]. 19655842572
detection of a lymphocytic choriomeningitis component in rabies virus preparations. 19655848338
use of beta-propiolactone in duck embryo rabies vaccine. 19695798765
[pathogenesis of allergic complications caused by viruses. i. development of infection in mice given repeated sublethal doses of fixed rabies virus]. 19655874471
[on the role of the rabies virus in the etiology of multiple sclerosis and encephalomyelitis]. 19655876802
further contributions to knowledge of the time during which rabies virus is bound. 19655882413
[agar gel precipitation test in laboratory animals inoculated with the rabies virus]. 19655882915
growth characteristics of rabies virus in primary chick embryo cells. 19655840891
[rabies in a wide-winged bat (eptesicus serotinus) in thuringia]. 19655894962
transmission experiments with bat rabies isolates: responses of certain carnivora to rabies virus isolated from animals infected by nonbite route. 19665913020
transmission experiments with bat rabies isolates: reaction of certain carnivora, opossum, and bats to intramuscular inoculations of rabies virus isolated from free-tailed bats. 19665913022
transmission experiments with bat rabies isolates: reactions of certain carnivora, opossum, rodents, and bats to rabies virus of red bat origin when exposed by bat bite or by intrasmuscular inoculation. 19665913032
pathogenesis of skunk rabies virus: quantitation in skunks and foxes. 19665913037
kinetic studies on growth of rabies virus in tissue culture. i. cell virus interaction. 19665930490
kinetic studies on growth of rabies virus in tissue culture. ii. the replication cycles in rabies virus infection. 19665930491
density gradient centrifugation studies on rabies virus.neurath, a. robert (the wistar institute, philadelphia, pa.), tadeusz j. wiktor, and hilary koprowski. density gradient centrifugation studies on rabies virus. j. bacteriol. 92:102-106. 1966.-cesium chloride density gradient centrifugation of rabies virus revealed a heterogeneous population of infectious virus particles, the majority of which showed a density of 1.20 g/ml. from results obtained by rate zonal centrifugation in preformed sucrose gradients, it was possible to calculate a sedimentat ...19665941269
[apropos of the formation of intermediate antigens in nervous tissue, infected by the fixed rabies virus]. 19665944295
alloxan-schiff reagent for the detection of fixed rabies virus in the nerve cell. 19665944358
autointerference of rabies virus in chick embryo fibroblasts. 19665951071
adaptation of rabies street virus strains to tissue culture. 19655850012
brain neutralization of rabies virus to distinguish recovered animals from previously vaccinated animals. 19665955831
rabies. 19695815668
"soluble" antigens from cells infected with rabies virus. 19665988229
[studies on the rabies virus in relation to insects. changes in virus fixé of rabies due to passage through larvae of the gypsy moth (porthetria dispar l)]. 19665992406
[use of human chromosomes for the investigation of the cytopathic effect of rabies virus]. 19665992754
[experimental studies on the problem of rabies transmission by flies]. 19665998339
[do the properties of a fixed rabies virus change in extracerebral passage?]. 19665954721
[multiplication of street rabies virus in primary culture of puppy kidney cells]. 19666002853
[a study of the stabilizing effect of a copolymer of vinyl alcohol and vinylamine on fixed rabies virus during its purification with freon]. 19666002943
rabies in tennessee swine. 19666006429
interferon production in hamsters experimentally infected with rabies virus. 19665958999
[on the isolation in brazilof rabies virus from the lung, heart and various other tissues of hematophagous vampire bats belonging to the species desmodus rotundus]. 19666011926
chiropteran (bat) rabies in north america. 19655891616
[effect of deoxyribonuclease on rabies virus]. 19666014608
comparative studies between pathogenesis of street and fixed rabies infection.comparative neuropathology of ammon's horn caused by both the street and fixed rabies infection was studied by combined light and electron microscopy. neurons containing negri bodies appeared comparatively little damaged. in striking contrast, in the case of fixed virus infection, neurons showed the following variety of degeneration. lightly damaged neurons showed an increase in the number of small vesicles throughout the cytoplasm. a considerable number of lysosomes were also encountered within ...19676016898
[antirabies vaccinations at the institut pasteur of lyon in 1966]. 19676065946
experimental rabies infection in the mexican freetail bat. 19676067473
separation of 'soluble' immunoprecipitating antigens originating from rabies virus infected cells by chromatography on ecteola cellulose and by gel filtration. 19676076336
influence of lipogenesis on growth of rabies virus in brown adipose adipose tissue of experimentally infected hamsters. 19676078218
monoclonal antibodies as a tool for rabies epidemiological studies.hybridoma-produced monoclonal antibodies specific of antigenic determinants of the nucleocapsid and the glycoprotein of rabies virus showed differences between fixed and street strains of rabies virus. standard panels of monoclonal antibodies allowed us to determine the geographic origin of imported cases of rabies in animals and humans.19846084611
investigation of the antigenic structure of rabies virus glycoprotein by monoclonal antibodies.comparative antigenic analysis of glycoprotein variants of era and cvs-11 strains of rabies virus by monoclonal antibodies has permitted the delineation of three antigenic sites on the glycoprotein common to both strains. two additional antigenic sites have been delineated on the era strain virus glycoprotein. the topologic relationship of these antigenic sites has been investigated.19846084612
characterization of rabies virus strains used for vaccine production by means of monoclonal antibodies.a group of who consultants who met in geneva 16-18 september 1982, recommended, among other items, that "monoclonal antibody reactivity pattern of all viruses used for (rabies) vaccine production should be established" (who/rab.res./82.15) (1). such a study has been undertaken in our who collaborative centre for rabies in close collaboration with the who collaborative centre for rabies of the wistar institute, and with monoclonal antibodies kindly supplied by t.j. wiktor (2).19846084613
[antigenic characteristics of strains of rabies isolated in madagascar]. 19846085460
[rabies in humans--confirmation of the existence of fast intra-axonal circulation in peripheral nerves]. 19846085743
[rabies, present-day disease]. 19666010705
[rabies in an insectivorous bat (rogheessa tumida tumida h. allen)]. 19666013772
protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene.inoculation of rabbits and mice with a vaccinia-rabies glycoprotein recombinant (v-rg) virus resulted in rapid induction of high concentrations of rabies virus-neutralizing antibodies and protection from severe intracerebral challenge with several strains of rabies virus. protection from virus challenge also was achieved against the rabies-related duvenhage virus but not against the mokola virus. effective immunization by v-rg depended on the expression of a rabies glycoprotein that registered p ...19846095272
effect of 9-(s)-(2,3-dihydroxypropyl)adenine on experimental rabies infection in laboratory mice.9-(s)-(2,3-dihydroxypropyl)adenine (dhpa) exerted a pronounced influence on experimental rabies infection in laboratory mice. it was effective in a dose range from 1 to 100 mg/kg body weight. intracerebral infection tended to be potentiated, intramuscular infection was partly or fully inhibited by the drug. peroral administration was the most effective. the results of individual experiments varied and depended on the sensitivity of the virus strains employed, the dose of dhpa given and the time ...19806108059
nonlethal infection of laboratory mice induced with "mouse" rabies strains.nonlethal infection was induced in laboratory mice with sublethal doses of rabies strains isolated from small wild rodents. three types of nonlethal infecion were observed: persistent--with virus irregularly reisolable for at least 56 days after inoculation: latent--with negative virus reisolation but presence of infection demonstrable by transmission of virus neutralization activity to other animals; and abortive--with only a primary immune response, nontransmissible to other animals. a hyperre ...19806108060
lagos bat virus in south africa. 19816111687
rabies: a little antibody a dangerous thing? 19816112418
rabies virus and laboratory regulations. 19816113412
rabies virus and laboratory regulations. 19816114274
rabies virus and laboratory regulations. 19816114354
freeing rabies virus of the neuroallergenic factor from brain tissue.a method of fixed rabies virus purification from infected sheep brains was proposed. it consisted of suspending the brain tissue in phosphate-buffered hypertonic (0.3 m) nacl solution, shaking at 37 degrees c and low speed centrifugation at the same temperature. from 65 to 85% ballast proteins were removed, the neuroallergenic activity of the material was lost, but practically no losses of the virus occurred.19816115564
separation of two street rabies virus strain populations into two biological variants. 19816115568
purification and concentration of rabies virus by chromatography on chemically modified porous silicates.tissue culture rabies virus was purified by gel chromatography on chemically modified macroporous glasses (mpg). modification of the mpg surface by egg or human albumin prevented rabies virions from interaction with the glass surface so that all purified virus was eluted from the column. chemically modified mpg could be used on a preparative scale for the purification of both infectious and inactivated rabies virus, the immunogenicity of the latter having been preserved. protein content of the p ...19816116414
multisite intradermal antirabies vaccination. immune responses in man and protection of rabbits against death from street virus by postexposure administration of human diploid-cell-strain rabies vaccine.lymphocyte transformation, production of neutralising antibody, and the development of antirabies igg antibody were studied in ten healthy volunteers in response to 0.8 ml of human diploid-cell strain (hdcs) rabies vaccine administered on one occasion in divided doses in 8 intradermal (i.d.) sites. all ten volunteers rapidly developed substantial titres of rabies antibody, and eight of the ten had t lymphocytes that were immunologically stimulated by hdcs rabies-virus antigen. postexposure treat ...19816117693
properties of rabies vaccine freed of neuroallergenic factor from brain tissue.fixed rabies virus in the form of infected sheep brain suspension was freed from approx. 80% of ballast proteins, inactivated by beta-propiolactone and lyophilized. the vaccine thus obtained was devoid of neuroallergenicity when tested on guinea pigs and was highly antigenic and immunogenic. the vaccine caused no generalized reactions in volunteers; local reactions were weak and of short duration. antibody formation was intensive in all volunteers.19816118049
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