Publications

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a rapid tissue culture test for determining rabies neutralizing antibody. 19734219507
the immunoperoxidase reaction for demonstration of rabies virus. 19734219508
laboratory techniques in rabies: rapid microscopic examination for negri bodies and preparation of specimens for biological test. 19734219509
the importance and histopathology of hypothalamic changes in animals inoculated intracerebrally with högyes' fixed strain of rabies virus. 19744219555
[isolation of the rabies virus from vampire bats in the state of são paulo, brazil]. 19664222504
immunofluorescence study of wild rabies virus and antibody.a concentrate of wild rabies antibody was prepared from hyperimmune serums of three dogs refractory to wild rabies. the animals resisted repeated intramuscular injections of large doses of wild rabies virus in emulsions of whole brain, in emulsions of submaxillary salivary glands, and in emulsified mixtures of brain and submaxillary glands taken from naturally rabid dogs. the antibody was conjugated with fluorochrome and then absorbed by a procedure that gave "cell-free" working solutions of flu ...19664222647
pathogenesis of rabies in the rat.three strains of rabies virus, one fixed and two street, were compared for invasiveness in neurectomized rats following foot pad inoculation. approximately one-fifth of test rats studied revealed that the virus bypassed the severed sciatic and saphenous nerves and reached the brain. all rats dying within 20 days were positive for rabies upon fluorescent antibody and mouse mortality tests. viremia was demonstrated in 20 per cent of both neurectomized or non-neurectomized rats one hour after inocu ...19674226678
[interference between vacciniavirus and street rabies virus]. 19664228364
[experience with the application of indirect immunofluorescence in rabies virus identification]. 19674229751
[studies on rabies in brazil. ii. isolation of the rabies virus from the lungs, kidney, bladder and tissues of other organs of the naturally infected domestic cat]. 19684230926
[importance of antiseptic selection for hempt's antirabies vaccine]. 19684232468
[rabies immunity in vaccinated cattle]. 19684234759
[spontaneous recovery of a dog artificially infected with rabies]. 19694240203
bat rabies in canada 1963-1967.six hundred and twenty-eight insectivorous bats originating from seven provinces were submitted to this institute for rabies diagnosis between august 1, 1963 and december 31, 1967. brain tissue was examined by the fluorescent antibody technique and the mouse infectivity test was carried out with brain, salivary gland, interscapular adipose tissue and kidney samples. rabies virus was detected in 44 bats, 29 of which were from ontario, 12 from british columbia and three from manitoba. most of the ...19694242773
[susceptibility of newborn and adult mice to rabies virus as demonstrated by immunofluorescence]. 19704247199
[the problem of the carrier in rabies]. 19694247989
[rabies in dogs in the city of cali]. 19704248635
sylvatic rabies studies in the silver fox (vulpes vulpes). susceptibility and immune response.the trials reported here show that the fox is highly susceptible to rabies virus. vaccination with era rabies vaccine was capable of protecting foxes against challenge with naturally occurring strains of sylvatic rabies.oral immunization against rabies using era rabies vaccine was possible.19704249093
[rabies virus isolation from insect eating bats in cordoba, argentina]. 19714253499
[complement fixation tests in the serology of rabies]. 19714254909
[first report in peru of paralytic bovine rabies transmitted by bats]. 19714256905
[detection of virus rabies]. 19724262436
[characteristics of a rabies virus strain isolated from the brain of desmodus rotundus]. 19724262443
the era strain of rabies vaccine.an antigenic extinction trial in cats showed that the era rabies vaccine had superior antigenic properties over flury h.e.p. c.e.o. and killed tissue culture rabies vaccine. dogs and cats on a duration of immunity study of era rabies vaccine were challenged with fox salivary gland "street" rabies virus. the results of this challenge show a duration of immunity of five years in dogs and four years in cats. vaccination of dams in late pregnancy with era rabies vaccine resulted in transference of m ...19724263912
studies on the scent glands and musk of rabid skunks (mephitis mephitis). 19734265546
comparative pathogenesis of rabies and rabies-like viruses. viral infection and transit from inoculation site to the central nervous system. 19734266465
[study of street rabies virus isolated in a natural focus]. 19724268420
[rabies virus in rats and mice inoculated intraplantarly]. 19734270888
gross chemical composition of strain flury hep rabies virus. 19734271865
the lipid composition of rabies virus. 19734271871
antibody production in milk serum after virus instillation of goat mammary gland vi. "sham infection" with special reference to rabies.the era strain of rabies vaccine virus failed to propagate or cause clinical manifestations when instilled into the mammary gland of lactating goats. however, the virus did produce neutralizing antibodies in this gland as a result of repetitive viral stimulation, a "sham infection". the protective property of the concentrated and partly purified milk serum antibody was assessed in mice. in the first trial, protective activity was observed when a single dose of milk serum antibody was administere ...19744272951
[isolation of the agent of neurotropic disease from murine rodents]. 19734273734
the diagnosis of rabies in a horse by brain neutralization test.a horse showing clinical signs of a neurological disorder was killed and various diagnostic tests for rabies were carried out. histopathlogy revealed a nonsuppurative encephalitis. fluorescent antibody test and mouse inoculation test were negative. a positive diagnosis of rabies was based on a high antibody titer (1:10,000) to rabies virus in brain tissue.19744277690
early street rabies virus infection in striated muscle and later progression to the central nervous system.twelve isolates of street rabies virus were inoculated intramuscularly into young hamsters and the course of infection was followed by frozen section immunofluorescence. animals infected with 10 of the 12 viruses had antigen in striated muscle at day 3, but involvement of other tissues was absent or extremely sparse. muscle infection was still most pronounced at day 6, but neuromuscular spindle, nerve, and brain infections were also detected in a majority of animals. progression of infection was ...19744282379
histamine level in the central nervous system in experimental rabies infection and immunization. 19724282798
antiviral activity of ammonium picrate in mice. 19664285507
inactivation of viruses by benzalkonium chloride.benzalkonium chloride (as roccal or zephiran) was found to inactivate influenza, measles, canine distemper, rabies, fowl laryngotracheitis, vaccinia, semliki forest, feline pneumonitis, meningopneumonitis, and herpes simplex viruses after 10 min of exposure at 30 c or at room temperature. poliovirus and encephalomyocarditis virus were not inactivated under the same conditions. it was concluded that all viruses tested were sensitive except members of the picorna group. the literature was reviewed ...19644288740
the rabiesviruses--a new group? 19664293030
[on the etiology of an unknown human infection originating from monkeys]. 19674294540
pathogenesis of viral infections of the nervous system. 19684295224
potential antiviral agents. carbobenzoxy di- and tripeptides active against measles and herpes viruses. 19684295313
the inhibition of rabies virus by arabinosyl cytosine. studies on the mechanism and specificity of action. 19684297124
hemagglutinin of rabies and some other bullet-shaped viruses. 19684297692
[the clinical picture and therapy of rabies]. 19684300749
studies of an established canine kidney-cell line. 19684301040
[immunoluminescent analysis of varuses with the contrast of non-specific luminescence]. 19674301336
enhanced replication of newcastle disease virus in cell culture co-infected with certain other viruses. 19684303423
characteristics of cell culture systems. viral flora of canine tissues. 19684305426
effect of 1 percent phenol on several bacterial and viral species. 19694309833
[latent viruses in the salivary glands]. 19694312310
interference between bovine parainfluenza 3 virus and a street strain of rabies virus in rabbits. 19704315630
vesicular stomatitis and related viruses. 19704322274
[stimulating interaction of animal viruses]. 19704323595
effect of administered interferon on rabies in rabbits.this study describes the effect of interferon on the survival of rabbits infected with a street strain of rabies virus. interferon was prepared by collecting serum from rabbits injected with newcastle disease virus and was characterized by biological and physicochemical methods. rabbit serum interferon mixed and incubated with a suspension of rabies virus did not neutralize its infectivity. rabbits were inoculated into the hind leg muscle with approximately 80 ld(50) of virus. interferon was adm ...19714330317
identification of selected animal viruses with fluorescent antibodies prepared from multivalent antiserums. 19714330674
possible mechanisms in the pathogenesis of "postinfectious" encephalomyelitis. 19714332337
[specific antigens in virus-infected cells]. 19714334954
[encephalomyelitis--with special reference to viral infection]. 19724338970
simultaneous budding of "c-type" particles and rhabdoviruses from individual reptilian cells. 19724339332
broad-spectrum antiviral activity of virazole: 1-beta-d-ribofuranosyl-1,2,4-triazole-3-carboxamide.virazole is a synthetic nucleoside active in tissue culture against at least 16 dna and rna viruses. applied topically, it inhibits herpetic keratitis in rabbits and tail lesions induced by herpes, vaccinia, and vesicular stomatitis viruses in mice. injected intraperitoneally into mice, it inhibits splenomegaly and hepatomegaly induced by friend leukemia virus and respiratory infections caused by influenza a(o), a(2), and b viruses and parainfluenza 1 virus. infections is also effective.19724340949
antibody response in vitro to an animal virus: production of rabies virus neutralizing antibodies by mouse cells in culture.rabies virus neutralizing antibodies were produced in vitro by the exposure of mouse spleen cells to live and inactivated rabies virus suspensions and to sheep erythrocytes coated with rabies virus. these antibodies did not neutralize two other rhabdoviruses: kern canyon and vesicular stomatitis viruses, and were precipitable by treatment with an antiserum to mouse igg. removal of "glass-adhering" cells from mouse spleen cell suspensions abolished the antibody response, which could be restored b ...19724341695
chronic rabies virus infection of cell cultures.exposure of both mammalian and reptilian cells in tissue culture to different strains of fixed rabies virus resulted in a carrier type of infection. no cytopathic effect was observed in either type of culture; infected cultures could be maintained by cell transfer for unlimited numbers of passages. a consistent pattern of cyclically rising and falling levels of viral infection was observed by fluorescent-antibody staining techniques and by titration of released infectious virus. resistance to su ...19724344636
demonstration by electron microscopy of viruses in cells found by light microscopy to contain inclusion bodies. 19724346228
advances in the serodiagnosis of viral infections. 19734348875
[study of the interfering activity of the vnukovo-32 vaccinal strain of the rabies virus]. 19734350240
a rabies-induced serum factor inhibiting rous sarcoma virus in chicks. 19734353209
rhabdoviruses. 19734355830
limitations of deteriorated tissue for rabies diagnosis. 19744357492
different sensitivity of ribonucleic and deoxyribonucleic acid viruses to resistance induced in rabbit cells (rk-13) by polyriboinosinic acid-polyribocytidilic acid.when a continuous line of rabbit kidney cells (rk-13) was exposed to polyriboinosinic acid polyribocytidilic acid [poly(ri).poly(rc)], the cells became resistant to the replication of a ribonucleic acid (rna) virus, vesicular stomatitis (vsv), but remained susceptible to the replication of two deoxyribonucleic acid (dna) viruses, pseudorabies and vaccinia. these differences were identical to previous findings with rk-13 cells pretreated with exogenous rabbit interferon. confirmation is thereby p ...19734357987
comparative characterization of a c-type virus-producing cell line (vsw) and a virus-free cell line (vh2) from vipera russelli. 19734358139
detection of homologous rna sequences among six rhabdovirus genomes.complete transcripts of the genome of vesicular stomatitis virus indiana strain have been used to hybridize to virion rna to determine if there is rna sequence homology among these viruses. cellular rna from cells infected by each of these viruses has also been used for hybridization with the homologous or heterologous virion rna. the results indicate that there is little exact sequence homology among these viruses.19744359427
an interfering component of rabies virus which contains rna. 19744360392
pathogenicity of mokola, a rabies-related virus, in baby mice. 19744361049
non-specific serum inhibitors of activity of haemagglutinins of rabies and vesicular stomatitis viruses. 19744361920
phosphate acceptor amino acid residues in structural proteins of rhabdoviruses.partial acid hydrolysates of the [(32)p]phosphate- or [(3)h]serine-labeled proteins of purified vesicular stomatitis, rabies, lagos bat, mokola, or spring viremia of carp virions and of purified intracellular nucleocapsids of these viruses have been analyzed by paper electrophoresis for the presence of phosphorylated amino acids. both phosphoserine and phosphothreonine, with the former predominant, were present in virion and nucleocapsid preparations that contained phosphoproteins. an exception ...19744365328
adult and embryonic gecko cells in vitro: growth characteristics, infection by rabies, sindbis and polyoma viruses, and transformation by sv40. 19744365679
nucleotide composition of the ribonucleic acid of rabies virus.the nucleotide composition of the ribonucleic acid of three strains of rabies virus was determined and found to be similar to that of vesicular stomatitis virus.19714366430
virus infections in bats. 19744367453
rhabdovirus replication in enucleated host cells.infection of enucleated tc-7 monkey cells with rabies virus resulted in the synthesis of virus-directed rna and the production of rabies antigens but not of infectious virus. the yield of infectious vesicular stomatitis virus from enucleated tc-7 cells, on the other hand, was almost as high as that from intact cells. inhibition of the mitochondrial functions of enucleated cells by treatment with ethidium bromide did not influence the development of rabies antigens or the production of infectious ...19744367906
transcribing complexes in cells infected by vesicular stomatitis virus and rabies virus.we analyzed cell extracts from bhk(21) cells infected with vesicular stomatitis virus (vsv) and rabies virus for in vitro rna polymerase activity. cells infected with vsv b virions exhibited several complexes with in vitro rna polymerase activity in sucrose gradients. these complexes synthesize vsv transcriptase product (4 to 18s) polyadenylated in rna complementary to virion rna. cells infected with a high multiplicity of b virions and t particles show only one rna polymerase complex active in ...19744369391
inhibitors against rabies virus present in normal rabbit sera. 19744370108
persistent noncytocidal vesicular stomatitis virus infections mediated by defective t particles that suppress virion transcriptase.infectious b virions of vesicular stomatitis virus were 100% lethal to bhk(21) (baby hamster kidney) cells when infecting alone, and persistent noncytocidal infection could not be achieved with cloned b virions alone. however, a mixture of b virions and homologous, short, defective, interfering particles (t particles) of a temperature-sensitive mutant of the virus regularly established persistently infected, noncytocidal carrier cultures. a long t particle was generated during establishment of t ...19744370255
structural phosphoproteins associated with ten rhabdoviruses. 19744372298
phosphoproteins, structural components of rhabdoviruses. 19734372781
[immunopathology in viral infections]. 19744374809
[serum dnaase i activity as a protective factor in infections caused by dna-genome viruses]. 19744375371
interference in tissue cultures induced by rabies virus. 19654379471
propagation of street rabies virus in primary cultures of dog kidney cells. 19664380470
adaptation of street rabies virus to primary syrian hamster kidney cell culture. 19664380522
propagation of fixed rabies virus in cell cultures. 19664381344
onset and possible site of rabies virus ribonucleic acid synthesis in the cell. 19674382133
study of the interfering activity of fixed rabies virus in various cell systems. 19674382994
process of adaptation of street rabies virus to dog kidney cell primary cultures. 19684385154
[trials on the antigenicity, protectivity and encephalitogenicity of the hempt vaccine and considerations on rabies protective vaccination in germany]. 19674386311
experimental respiratory infection induced by rabies virus variants adapted to tissue culture. 19694389039
comparative titrations of street rabies virus according to the cytopathic effect and by immunofluorescence in tissue cultures and in mice. 19694389044
experimental inhalation infection of laboratory rodents with rabies virus. 19694389107
development of inhalation rabies infection in suckling guinea pigs. 19694389108
mechanism of perpetuation of animal viruses in nature. 19694392000
kinetics of reaction of rabies virus with specific antibodies in conditions on in vitro virus neutralization test. 19704392920
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