Publications

the proteins of biologically active sub-units of vesicular stomatitis virus.		1970	4318435
homotypic and heterotypic interference by defective particles of vesicular stomatitis virus.		1970	4318492
proteins of vesicular stomatitis virus. ii. immunological comparisons of viral antigens.	the antigens of the nucleoprotein core and the coat of vesicular stomatitis virus (vsv) particles of the indiana serotype were prepared and purified by sucrose gradient fractionation. antibody was prepared separately to each of the two antigen fractions. by immunological procedures, it was shown that soluble antigens of vsv preparations sedimenting at 20s and in the leading edge of the 6s region are antigenically related to vp3, the protein of the virus core, whereas the 6s soluble antigen cross ...	1970	4319479
intracellular site of rna replication of vesicular stomatitis virus as revealed by radioautography.		1970	4319730
immunogenicity of oncolysates obtained from ehrlich ascites tumors infected with vesicular stomatitis virus.		1970	4319863
studies on the multiplication of vesicular stomatitis virus with fluorescein and ferritin conjugated antibodies.		1970	4320021
[adaptation of the vesicular stomatitis virus to drosophila melanogaster].		1970	4320200
replication of vesicular stomatitis virus. i. viral specific rna and nucleoprotein in infected l cells.		1970	4320668
inhibitory effect of ultraviolet-inactivated vesicular stomatitis virus on initiation o dna synthesis in cultured chick embryo cells.		1970	4320686
protein synthesis in vesicular stomatitis virus-infected hela cells.		1970	4321299
isolation and characterization of temperature-sensitive mutants of vesicular stomatitis virus.		1970	4321310
ribonucleic acid synthesis of vesicular stomatitis virus. 3. multiple complementary messenger rna molecules.		1970	4321313
polysomal ribonucleic acid of vesicular stomatitis virus-infected hela cells.		1970	4321314
effect of u.v.-irradiated vesicular stomatitis virus on nucleic acid synthesis in chick embryo cells.		1970	4321565
[genetic study of vesicular stomatitis virus: classification of spontaneous thermosensitive mutants into complementation groups].		1970	4321566
relative antiviral resistance induced in homologous and heterologous cells by cross-reacting interferons.	human cells incubated with human interferon become more resistant to vesicular stomatitis virus (vsv) than to semliki forest virus (sfv); monkey cells treated with monkey interferon become more resistant to sfv than to vsv. however, monkey cells incubated with human interferon developed relative antiviral activity identical to that induced by homologous interferon, and human cells developed characteristic human interferon-induced relative antiviral activity when exposed to monkey interferon. the ...	1970	4322082
[demonstration of a serological difference between the virus adapted to drosophila and the initial strain of the vesicular stomatitis virus].		1970	4322112
inactivation of vesicular stomatitis virus by disinfectants.	twenty-four chemical disinfectants considered to be viricidal were tested. ten disinfectants were not viricidal for vesicular stomatitis virus within 10 min at 20 c when an ld(50) titer of 10(8.5) virus units per 0.1 ml were to be inactivated. quantitative inactivation experiments were done with acid, alkaline, and a substituted phenolic disinfectant to determine the kinetics of the virus inactivation. substituted phenolic disinfectants, halogens, and cresylic and hydrochloric acids were viricid ...	1970	4313317
ecologic studies of vesicular stomatitis virus. ii. results of experimental infection in panamanian wild animals.		1970	4313556
concentration and purification of vesicular stomatitis virus by polyethylene glycol "precipitation".		1970	4314510
polyacetal carboxylic acids: a new group of antiviral polyanions.	chlorite-oxidized oxypolysaccharides are polyacetal carboxylic acids. they inhibited the cytopathic effect of vesicular stomatitis virus in mouse embryo cell cultures challenged at low input multiplicity. after intraperitoneal injection of these compounds in mice, interferon appeared in the circulation. the compounds also protected mice against lethal mengovirus infection and against the development of experimental pox lesions on the tail. chlorite-oxidized oxyamylose was antiviral only when at ...	1970	4314553
inhibition of sindbis virus production by media of low ionic strength: intracellular events and requirements for reversal.	incubation of sindbis virus-infected cultures in medium with an ionic strength of 0.105 reduced the virus yield more than 99%. this inhibition was rapidly reversed by exposing the cultures to normal medium: within 20 min the previously inhibited cultures had released as much infectious virus as normal controls had produced during hours of incubation. the following intracellular processes were essentially normal in inhibited, infected monolayers: protein and phospholipid synthesis, the synthesis ...	1970	4315161
bats as possible maintenance hosts for vesicular stomatitis virus.		1970	4317161
the role of interferon in the protective effect of a synthetic double-stranded polyribonucleotide against intranasal vesicular stomatitis virus challenge in mice.	intravenous injection of polyinosinic acid/polycytidylic acid [(poly ri).(poly rc)] offered significant protection against intranasal challenge of young mice with vesicular stomatitis virus (vsv). optimal protection was obtained when a single dose was administered 2 hr before virus challenge, but repeated doses were effective when started as late as 3 days after virus challenge. the therapeutic ratio or ratio of maximum tolerated dose to minimum effective dose for a single intravenous injection ...	1970	4317283
effect of persistent fibroma virus infection on susceptibility of cells to other viruses.	shope fibroma virus establishes a persistent cytoplasmic infection in primary (rk) and serially cultivated (drk(3)) rabbit kidney cells which is accompanied by a morphological alteration of the cells. the response of such cells to superinfection by other viruses was compared with that of control cells by determining plaque production and virus yield of superinfecting viruses. it was found that the growth of other poxviruses, myxoma and vaccinia, was greatly inhibited in the fibroma virus-infecte ...	1970	4317346
homologous viral interference: induction by rna from defective particles of vesicular stomatitis virus.	the viral rna isolated from the defective particles of vesicular stomatitis virus was capable of interfering with the replication of this virus in chick embryo cells. the data indicate that the interfering ability of the defective particles of this virus is due to their nucleic acid component.	1970	4317405
phenotypic mixing of envelope proteins of the parainfluenza virus sv5 and vesicular stomatitis virus.	cells mixedly infected with parainfluenza virus sv5 and vesicular stomatitis virus (vsv) yield phenotypically mixed virions, in addition to both parental types. two types of phenotypically mixed virions have been identified: 0.6 to 1.2% of the vsv plaque formers were neutralized by sv5 antiserum, but not by vsv antiserum, suggesting the presence of a vsv genome in an sv5 envelope; 9 to 45% of the vsv plaque formers were neutralized by both antisera, indicating the presence of both sv5 and vsv an ...	1970	4315959
age-related cellular resistance of the chicken embryo to viral infections. i. interferon and natural resistance to myxoviruses and vesicular stomatitis virus.		1970	4316147
vesicular stomatitis virus--a new interfering particle, intracellular structures, and virus-specific rna.		1970	4097494
[analysis of synthesis of viral rna of the vesicular stomatitis virus (vsv). use of thermosensitive mutants].		1970	4097851
[effects of vesicular stomatitis virus on the metabolism of proteins and ribonucleic acids of chick embryo cells].		1970	4098232
morphogenesis of the nucleoprotein of vesicular stomatitis virus.	accumulation of the nucleoprotein of vesicular stomatitis virus (vsv) in the cytoplasm of bhk-21 cells and in two of four human cell lines was demonstrated. appearance and progression of the nucleoprotein inclusions paralleled development of virus-specific immunofluorescence and production of virus progeny. the inclusions appeared early as discrete foci of filamentous material which eventually increased in size to form large masses which replaced normal cytoplasmic constituents. the filamentous ...	1970	4100528
potentiating effect of freund's adjuvant on interferon production by endotoxin or poly ri*poly rc.	intraperitoneal injection of mice with mineral oil, incomplete (ifa) or complete freund's adjuvant (cfa) increased the interferon response to endotoxin or (poly ri)*(poly rc) administered intravenously 2 days later. after endotoxin administration, circulating interferon titers were increased at several different times of sampling and with a variety of endotoxin dosages. when injection of endotoxin was delayed until 6 to 8 days after the administration of ifa or cfa, interferon production was mar ...	1970	16557802
survey for vesicular stomatitis virus neutralizing antibodies in serums of white-tailed deer odocoileus virginianus of the southeastern united states.	new jersey type vesicular stomatitis (vs) antibodies were found in 14 of 677 deer serums tested by neutralization tests in embryonated chicken eggs. twelve positive serums were received from louisiana and two from georgia. eight of the positive deer serums from louisiana were collected in the area of the only reported case of vs during 1967. clinical vs has not been diagnosed in the east coast states since 1964. two positive deer serums were collected on ossabaw island, georgia, and three positi ...	1970	16512162
effect of interferon and interferon inducers on infections with a nonviral intracellular microorganism, rickettsia akari.	the effect of mouse interferon (if) on the multiplication of rickettsia akari in homologous (l-929) cell cultures and the effect of if inducers on r. akari infection in mice were investigated. there was a reduction in the proportion of cells containing rickettsiae in if-treated cultures and in the yield of rickettsiae from these cultures, as compared with those from infected cultures without if. trypsin treatment and heating for 1 hr at 65 c destroyed this antirickettsial activity of the if prep ...	1971	16558061
temperature-sensitive mutants of vesicular stomatitis virus: synthesis of virus-specific proteins.	viral proteins synthesized in l cells infected with temperature-sensitive (ts) mutants of vesicular stomatitis (vs) virus at permissive (31 c) and nonpermissive (39 c) temperatures were compared by polyacrylamide gel electrophoresis. mutant ts 5, deficient in synthesis of viral ribonucleic acid (rna(-)), failed to synthesize any of the five identifiable viral proteins at 39 c. each of three rna(+) mutants, representing three separate complementation groups, showed distinctive patterns of viral p ...	1971	4104253
defective particles in bhk cells infected with temperature-sensitive mutants of vesicular stomatitis virus.	defective particles were the major product after undiluted passage of certain temperature-sensitive (ts) mutants of the indiana c strain of vesicular stomatitis virus in bhk-21 cells at the permissive temperature (31 c). essentially homogeneous preparations of defective particles were obtained with the wild-type and individual ts mutants. the defective particles associated with some of the ts mutants, however, were morphologically and physically distinguishable from wild type and from each other ...	1971	4107244
proteins of vesicular stomatitis virus and of phenotypically mixed vesicular stomatitis virus-simian virus 5 virions.	the identity of the glycoprotein of vesicular stomatitis virus (vsv) as the spike protein has been confirmed by the removal of the spikes with a protease from streptomyces griseus, leaving bullet-shaped particles bounded by a smooth membrane. this treatment removes the glycoprotein but does not affect the other virion proteins, apparently because they are protected from the enzyme by the lipids in the viral membrane. the proteins of phenotypically mixed, bullet-shaped virions produced by cells m ...	1971	4108932
cytopathology of vesicular stomatitis virus with phase microscopy.		1971	4108651
electron microscopic study of development of vesicular stomatitis virus using ferritin-labelled antibodies.		1971	4108672
use of antiviral-antiferritin hybrid antibody for localization of viral antigen in plasma membrane.	reduced fab' fragments of viral antibody hybridized with reduced fab' fragments of antiferritin immunoglobulin g bind to viral antigenic sites in the plasma membrane of l cells infected with vesicular stomatitis virus. the hybrid antibody reacts specifically with ferritin, which can be identified by electron microscopy, and with fluorescein-conjugated apoferritin, which can be identified by fluorescence microscopy.	1971	4106782
induction of tumor immunity in mice with antigens prepared from influenza and vesicular stomatitis virus grown in suspension culture of ehrlich ascites cells.		1971	4325929
properties of the product synthesized by vesicular stomatitis virus particles.		1971	4326403
vesicular stomatitis virus, indiana serotype: multiplication in and transmission by experimentally infected phlebotomine sandflies (lutzomyia trapidoi).		1971	4327378
[a decrease in vesicular stomatitis virus plaque size in the presence of diethylaminoethyldextran (deaed) and isolation of a mutant resistant to deaed].		1971	4327851
comparison of the ribonucleic acid polymerases of two rhabdoviruses, kern canyon virus and vesicular stomatitis virus.	a ribonucleic acid (rna)-dependent rna polymerase has been demonstrated in kern canyon virus (kcv) particles. the rna product of the kcv polymerase hybridizes to kcv viral rna. the properties of this viral enzyme have been characterized and compared with those of vesicular stomatitis virus (vsv). rna polymerases from both viruses require similar conditions of temperature, ph, and detergent and magnesium concentrations for maximal synthesis of rna. the rna polymerase contained in the virion of kc ...	1971	4327891
preliminary physiological characterization of temperature-sensitive mutants of vesicular stomatitis virus.	different temperature-sensitive mutants of vesicular stomatitis virus have been characterized in terms of their ability to induce synthesis of viral ribonucleic acid (rna) in bhk-21 cells at 39 c (the restrictive temperature for these mutants). mutants belonging to complementation groups i and iv (and probably ii) did not induce actinomycin-resistant rna synthesis in infected cells incubated at 39 c. all three mutants comprising complementation group iii induced viral rna synthesis at 39 c. the ...	1971	4328415
comparison of microtiter procedures with the plaque technique for assay of vesicular stomatitis virus.	this paper describes a microprocedure for the tissue culture assay of vesicular stomatitis virus (vsv) and compares the sensitivity of the method with the conventional plaque assay of viral concentration. microtiter and plaque assay methods were used in titrations, neutralization tests, and thermoinactivation studies with this virus in chick embryo fibroblasts (cef) and l, hela, and pk cell lines. titration experiments with vsv by the microtiter procedure on preformed monolayers were significant ...	1971	4324192
semi-micro, dye-binding assay for rabbit interferon.	the semi-micro method for interferon assay was based on quantitation of inhibition of cytopathic effects in 6-mm wells. cultures were exposed to interferon dilutions, challenged with vesicular stomatitis virus, and stained with methylrosanaline chloride. the bound dye was then eluted and measured colorimetrically. the method was more sensitive than the plaque-inhibition method and was extremely economical. culture age was the most important factor affecting reproductibility.	1971	4325022
kinetics of rna synthesis by vesicular stomatitis virus particles.		1971	4325542
interactions of vesicular stomatitis virus structural proteins with hela plasma membranes.		1971	4325710
number and molecular weights of foot-and-mouth disease virus capsid proteins and the effects of maleylation.	evidence was obtained by gel electrophoresis that foot-and-mouth disease virus (fmdv) type a(12) protein migrates mainly in a zone corresponding to polypeptide(s) approximately 25,000 daltons in molecular weight. additional minor components were observed, four with molecular weights ranging from 10,000 to 22,500 daltons and one with a molecular weight of 37,500 daltons. the minor components comprised about 10% of the total protein and were present in variable amounts. the 75s empty capsids conta ...	1971	4329399
complete transcription by the transcriptase of vesicular stomatitis virus.	vesicular stomatitis virus (vsv) transcriptase completely transcribes the vsv genome into messenger-size ribonucleic acid (rna) species. the replicating complexes of template and product rna, generated in vitro by vsv transcriptase, exhibit a mass parity between product and template molecules. purified product rna, after annealing to small amounts of viral rna, rendered 92% of the viral rna ribonuclease-resistant. it is calculated that, under optimal conditions, 60 min is required before the vsv ...	1971	4329565
[study of the co 2 sensitivity symptom induced by vesicular stomatitis virus in drosophila melanogaster. i. vsv of the new jersey serotype and the cocal virus].		1971	4329708
[analysis of a thermolabile mutant of vesicular stomatitis virus (vsv)].		1971	4329750
enhancement of vesicular stomatitis virus production by serum.		1971	4329813
interferon action: inhibition of vesicular stomatitis virus rna synthesis induced by virion-bound polymerase.	the particle-bound rna polymerase activity of vesicular stomatitis virus (vsv) can be demonstrated in vivo. linear synthesis of viral rna persists for 5 to 6 hours at 34 degrees c in infected monolayers of chick embryo cells treated with cycloheximide and actinomycin d to block synthesis of protein and cell-specific rna. at least 55 percent of the rna made under these conditions is complementary to virion rna. rna synthesis mediated by vsv polymerase activity is inhibited in cells first treated ...	1971	4329841
effect of polyionic compounds on the plating efficiency of some strains of vesicular stomatitis virus.		1971	4330136
ribonucleic acid polymerase in virions of newcastle disease virus: comparison with the vesicular stomatitis virus polymerase.	the virions of newcastle disease virus (ndv) contained an enzyme that catalyzed the incorporation of ribonucleotides into ribonucleic acid (rna). optimal conditions for this polymerase activity were identical to the conditions for the vesicular stomatitis virus (vsv) polymerase, and both enzymes were active for longer times at 32 c than at 37 c. however, the specific activity of the ndv polymerase was less than 3% that of the vsv polymerase. product rna species from the ndv and vsv polymerase re ...	1971	4323712
absence of interference during high-multiplicity infection by clonally purified vesicular stomatitis virus.	stocks of vesicular stomatitis virus free of defective interfering particles were produced by serial clonal isolation. high-multiplicity infections with these stocks led to no interference or formation of defective interfering particles. defective interfering particles were generated by three successive passages at high multiplicity.	1971	4323713
carbohydrate composition of vesicular stomatitis virus.	analysis by gas-liquid chromatography of the trimethylsilylated sugar residues of purified vesicular stomatitis virus grown in l cells or chick embryo cells revealed the presence in the whole virion of four hexoses (glucose, galactose, mannose, and fucose), two hexosamines (glucosamine and galactosamine), and 34 to 40% neuraminic acid. the isolated viral glycoprotein was devoid of galactosamine and fucose, both of which sugars were present in whole virions presumably as part of the membrane glyc ...	1971	4323714
glycolipid content of vesicular stomatitis virus grown in baby hamster kidney cells.	vesicular stomatitis virions grown in baby hamster kidney (bhk-21-f) cells were found to contain hematoside (neuraminosyl-galactosyl-glucosyl-ceramide). this ganglioside, which was the only detectable glycolipid in the virion, is also the only glycolipid found in significant amount in bhk-21-f cells. approximately 87% of the total neuraminic acid in the virion was found to be linked to protein and 13% to lipid.	1971	4323715
comparative study of the efficacy of different forms of interferon therapy in the treatment of mice challenged intranassaly with vesicular stomatitis virus (vsv).		1971	4331092
temperature-sensitive mutants of vesicular stomatitis virus. ii. evidence of defective polymerase.		1971	4331110
dye uptake assay: an efficient and sensitive method for human interferon titration.	currently, human interferon (if) assays are generally performed by plaque reduction or visual cytopathic effect methods. both are time-consuming, subjective in interpretation, and, in the case of the latter, relatively insensitive. an adaption of the dye uptake method for human if titration which uses foreskin-derived fibroblasts and vesicular stomatitis virus is described. this assay is reproducible and sensitive (1 unit = 3 international units). by direct comparison, however, it is somewhat le ...	1971	4331773
entry of vesicular stomatitis virus into l cells.	early stages of the entry of vesicular stomatitis (vs) virus into l cells were followed by electron microscopy with the aid of ferritin antibody labeling. cells which were infected at 0 c and incubated for 10 min at 37 c were reacted first with antiviral-antiferritin hybrid antibody and then with ferritin or fluorescein-labeled apoferritin. extensive ferritin labeling of the cell surface was detected by both electron and fluorescence microscopy. the labeled regions of the cell surface were conti ...	1971	4332145
the intracellular development of vesicular stomatitis virus and two of its mutants.		1971	4332938
proteins of vesicular stomatitis virus. 3. intracellular synthesis and extracellular appearance of virus-specific proteins.		1971	4332974
[effect of ph reduction on the development of vesicular stomatitis virus].		1971	4333204
identification of vesicular stomatitis virus nucleoprotein in situ.		1971	4333710
replication of vesicular stomatitis virus: characterization of the virus-induced rna.		1971	4333717
[functions of vesicular stomatitis virus modified by a temperature-sensitive mutation: demonstration of the structural protein affected by the matation ts 23].		1971	4334300
a search for recombination between temperature-sensitive mutants of vesicular stomatitis virus.		1971	4334303
[ultrastructure of vesicular stomatitis virus].		1971	4335269
[effects of vesicular stomatitis virus on ribonucleic acid metabolism in chick embryo cells: study in the presence of cycloheximide].		1971	4340381
neuropathological and immunofluorescence studies of experimental vesicular stomatitis virus encephalitis in mice.		1971	4336813
use of disposable micro tissue culture plates for antiviral and interferon induction studies.	a reproducible test system requiring small amounts of test compound was developed for evaluating antiviral and interferon-inducing activity. in the antiviral experiments, kb cells were grown in disposable polystyrene microplates covered with a standard domestic plastic wrap. viruses used in the system were types 1 and 2 herpes simplex virus, vaccinia virus, type 3 adenovirus, myxoma virus, pseudorabies virus, type 3 parainfluenza virus, types 1a and 13 rhinovirus, vesicular stomatitis virus, cox ...	1971	4332040
the homologies of spontaneous and induced temperature-sensitive mutants of vesicular stomatitis virus isolated in chick embryo and bhk 21 cells.		1971	4327580
isolation and characterization of temperature-sensitive mutants of vesicular stomatitis virus, new jersey serotype.	forty-eight temperature-sensitive (ts) mutants have been isolated from a wild-type strain of the new jersey serotype of vesicular stomatitis virus (vsv) after exposure to the base analogue mutagen 5-fluorouracil. of these mutants, 47 have been classified into 6 nonoverlapping complementation groups containing 21, 17, 4, 3, 2, and 1 mutant, respectively (1 mutant remaining unallocated). the ribonucleic acid (rna) phenotype of 23 of these mutants has been established. four of the six groups contai ...	1971	4366429
nucleotide composition of the ribonucleic acid of rabies virus.	the nucleotide composition of the ribonucleic acid of three strains of rabies virus was determined and found to be similar to that of vesicular stomatitis virus.	1971	4366430
temperature-sensitive mutants of vesicular stomatitis virus: in vitro studies of virion-associated polymerase.	the temperature dependence of the virion-associated polymerase activity of six temperature-sensitive (ts) mutants of vesicular stomatitis virus (tsw10, 11, 14, 16b, 28, and 29) has been examined in vitro and compared to the heat-resistant parent (hr). the polymerase of five of the mutants (tsw10, 11, 14, 16b, and 28) appears to be significantly more ts than that of hr. because certain pairs of these five mutants can complement each other's in vitro polymerase activity, it appears that in vitro s ...	1972	4345492
adenylate-rich sequences in vesicular stomatitis virus messenger ribonucleic acid.	vesicular stomatitis virus (vsv)-specific messenger ribonucleic acid (mrna) species contain sequences of adenylate-rich rna which are more heterogeneous in their migration through sodium dodecyl sulfate-polyacrylamide gels than the corresponding fractions from hela cell mrna. vsv virion rna contains no adenylaterich sequences. the possible role of such sequences in the mrna species of a cytoplasmically replicating virus is discussed.	1972	4343546
mutant of vesicular stomatitis virus which allows deoxyribonucleic acid synthesis and division in cells synthesizing viral ribonucleic acid.	some temperature-sensitive mutants of vesicular stomatitis virus were tested for their ability to block the initiation of deoxyribonucleic acid (dna) synthesis and division in serum-stimulated hamster embryo fibroblasts at the nonpermissive temperature. although the parental strain blocked these processes, one particular mutant allowed essentially normal dna synthesis and division. by autoradiography, it was shown that individual cells infected with this mutant could synthesize viral ribonucleic ...	1972	4343543
model for vesicular stomatitis virus.	vesicular stomatitis virus contains single-stranded ribonucleic acid of molecular weight 3.6 x 10(6) and three major proteins with molecular weights of 75 x 10(3), 57 x 10(3), and 32.5 x 10(3). the proteins have been shown to be subunits of the surface projections, ribonucleoprotein, and matrix protein, respectively. from these values and from estimates of the proportions of the individual proteins, it has been calculated that the virus has approximately 500 surface projections, 1,100 protein un ...	1972	4342242
genome homology of vesicular stomatitis virus and defective t particles and evidence for the sequential transcription of the virion ribonucleic acid.	the small defective t particle of vesicular stomatitis virus (vsv-111) has no detectable enzyme activity when assayed at 31 c, although qualitatively it possesses all the virion proteins found in complete vsv-1 virions. with vsv-1 transcription product ribonucleic acid (rna), it is shown that the vsv-111 rna is identical to part of the vsv-1 genome. evidence is also presented to support the idea that in vitro vsv-1 transcription is sequential.	1972	4338640
[action of rifampicin on the vesicular stomatitis virus].		1972	4335152
virus-induced interference in heterologously infected hela cells.	in doubly infected hela cells, poliovirus type 1 rapidly and completely dominates vesicular stomatitis virus (vsv) plaque-forming unit production. poliovirus type 1 shuts off incorporation of amino acids into vsv-specific proteins within 2 hr after superinfection of cells already committed to massive synthesis of vsv proteins. however, poliovirus type 1 appears to have little, if any, direct effect upon incorporation of uridine into vsv-directed ribonucleic acid (rna) synthesis. poliovirus appar ...	1972	4333542
phenotypic mixing of vesicular stomatitis virus with fowl plague virus.		1972	4401067
response of cultured mammalian cells to diphtheria toxin. iv. isolation of kb cells resistant to diphtheria toxin.	kb cell strains which are resistant to the lethal effects of diphtheria toxin were isolated from the toxin-sensitive kb cell line. for one such strain, kb-r2, the concentration of diphtheria toxin required to cause a 50% reduction of incorporation of amino acids into protein was more than 2,000 times that required in the sensitive kb-s cell. the kb-r2 strain was cloned by a single-cell isolation method to yield uniform strains with an even greater resistance to toxin. resistance is a stable, inh ...	1972	4634953
interferon administered orally: protection of neonatal mice from lethal virus challenge.	interferon was identified in the milk of mice injected with an interferon inducer. the kinetics of interferon appearance in serum and in milk were similar, but maximum concentrations in milk were 10 to 20 percent of those in serum. interferon administered orally to neonatal mice was detected in their serums. significantly more newborns survived an oral challenge with vesicular stomatitis virus when interferon had been induced in the lactating mothers.	1972	4338344
correlation of messenger rna function with adenylate-rich segments in the genomes of single-stranded rna viruses.	oligonucleotides enriched in adenylate residues have been demonstrated in the genomes of two positive-strand rna viruses, sindbis and columbia sk. such oligonucleotides were not found in the genome of vesicular stomatitis virus, a negative-strand virus. the adenylate-rich oligonucleotides from sindbis and columbia sk viruses appeared similar when analyzed by zonal sedimentation in sucrose-sodium dodecyl sulfate.	1972	4338595
incorporation of l cell sterols into vesicular stomatitis virus.	the incorporation of host cell sterol into vesicular stomatitis virus can be effectively studied in an l cell system. the end product of de novo sterol synthesis in the l cell is desmosterol, and as the concentration of cholesterol in the medium is increased the cells incorporate the exogenous cholesterol and the synthesis of desmosterol decreases. l cells which contained desmosterol as their sole sterol produced virus whose sterol content was similarly composed of only desmosterol. virus grown ...	1972	4338636
ribonucleic acid synthesis of vesicular stomatitis virus. iv. transcription by standard virus in the presence of defective interfering particles.	exposure of vesicular stomatitis virus-infected chinese hamster ovary cells to cycloheximide results in the complete transcription of virion ribonucleic acid (rna) into only 28s and 13 to 15s viral-specific rna species. these rna are identical to viral messenger rna by the following criteria: size, single-strandedness, complementarity to virion rna, and formation of messenger ribonucleoproteins. this transcription represents the intracellular enzymatic activity of the virion-associated polymeras ...	1972	4338638
pseudotypes of vesicular stomatitis virus with the coat of murine leukaemia and of avian myeloblastosis viruses.		1972	4339183
glycolipid nature of the complement-fixing host cell antigen of vesicular stomatitis virus.		1972	4339184
comparison of structural polypeptides from vesicular stomatitis virus (indiana and new jersey serotypes) and cocal virus.		1972	4340280
swine interferon. ii. induction in pigs with viral and synthetic inducers.	the production of interferon by pigs in response to viral and synthetic inducers was studied. the inducers used included polyriboinosinic-polyribocytidylic acid (poly i:c), swine influenza virus and pseudorabies virus. following intravenous inoculation of pigs with the inducers, sera were examined for interferon by the plaque-reduction method in porcine kidney (pk(15)) cell cultures using vesicular stomatitis virus as the challenge inoculum. it was shown that pigs can produce interferon in respo ...	1972	4340346
inhibition of vesicular stomatitis virus replication by 9-beta-d-arabinofuranosyladenine.	9-beta-d-arabinofuranosyladenine (ara-a) effectively inhibited the production of infectious vesicular stomatitis virus (vsv) in mdbk cells. furthermore, inhibition was shown to begin as early as the first 3 hr of infection. studies employing (3)h-l-leucine indicated that ara-a did not affect protein synthesis in uninfected cells, although it did cause a marked stimulation of protein synthesis in vsv-infected cells during the log phase of the growth cycle. puromycin, an inhibitor of protein synth ...	1972	4364172
classification of rhabdovirus proteins: a proposal.	a simple alphabetical classification is offered as a means to codify the proteins of rhabdoviruses, using vesicular stomatitis virus as the prototype.	1972	4345495
replication of vesicular stomatitis virus: the effect of purified interfering component.		1972	4346652