Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| characterization of rotavirus strains detected among children and adults with acute gastroenteritis in gizan, saudi arabia. | 2008 | 18454236 | |
| virus-specific intestinal ifn-gamma producing t cell responses induced by human rotavirus infection and vaccines are correlated with protection against rotavirus diarrhea in gnotobiotic pigs. | we examined rotavirus-specific ifn-gamma producing cd4+, cd8+ and cd4+cd8+ t cell responses in gnotobiotic pigs infected with a virulent human rotavirus (virhrv) or vaccinated with an attenuated (att) hrv vaccine (atthrv3x or atthrv2x) or an atthrv oral priming and 2/6-virus-like particle (vlp) intranasal boosting (atthrv-2/6vlp) regimen. in virhrv infected pigs, hrv-specific ifn-gamma producing t cells reside primarily in ileum. atthrv-2/6vlp induced similar frequencies of intestinal ifn-gamma ... | 2008 | 18456375 |
| [epidemiology and burden of rotavirus diarrhea in day care centers in lyon, france]. | rotavirus is the main cause of severe, dehydrating diarrhoea in infants and young children. in industrialized countries, pediatric rotavirus gastroenteritis (prge) is responsible for high morbidity, particularly among children under 3 years of age attending day care centers (dccs). the objectives of this study were to estimate the incidence, management and cost of prge in dccs. we also described the nature of group a rotavirus genotypes. this study also compared the performance of different diag ... | 2008 | 18456480 |
| acrylamide concentration affects the relative position of vp7 gene of serotype g2 strains as determined by polyacrylamide gel electrophoresis. | during the course of development and characterization of various rotavirus reassortants, we found that the relative position of the gene encoding neutralization and protective antigen vp7 of certain rotavirus strains in a page gel was influenced by the concentration of acrylamide. | 2008 | 18457989 |
| nosocomial rotaviral gastroenteritis in paediatric departments. | the authors present a retrospective analysis of community-acquired and hospital-acquired rotaviral gastroenteritis (rvge) cases in a 5 years period 2001-2005 and prospective analysis in 2006 in the referral area in a population of 7,000 children under 5 years of age. out of 228 patients with rvge, nosocomial rvge accounted for 27.75% of the cases. children with nosocomial rvge were in average 9.8 months younger compared to patients with community-acquired rvge. nosocomial cases were also charact ... | 2008 | 18459473 |
| rotavirus vaccination in europe: the time has finally arrived. | 2008 | 18460968 | |
| rotavirus. | 2008 | 18460969 | |
| options for the prevention of rotavirus disease other than vaccination. | 2008 | 18460970 | |
| european society for paediatric infectious diseases/european society for paediatric gastroenterology, hepatology, and nutrition evidence-based recommendations for rotavirus vaccination in europe. | 2008 | 18460971 | |
| appendix i: methods for the development of evidence-based recommendations. | 2008 | 18460972 | |
| acute diarrhea in children in europe: do we know how to treat it? | 2008 | 18460973 | |
| foreword: espid/espghan evidence-based recommendations for rotavirus vaccination in europe. | 2008 | 18460975 | |
| foreword: espghan/espid evidence-based guidelines for the management of acute gastroenteritis in children in europe. | 2008 | 18460976 | |
| probiotics, prebiotics, and synbiotics. | according to the german definition, probiotics are defined viable microorganisms, sufficient amounts of which reach the intestine in an active state and thus exert positive health effects. numerous probiotic microorganisms (e.g. lactobacillus rhamnosus gg, l. reuteri, bifidobacteria and certain strains of l. casei or the l. acidophilus-group) are used in probiotic food, particularly fermented milk products, or have been investigated--as well as escherichia coli strain nissle 1917, certain entero ... | 2008 | 18461293 |
| sequence and phylogenetic analysis of the vp4 gene of human rotaviruses isolated in paraguay. | nucleotide and amino acid analyzes of the vp4 gene of human rotaviruses isolated both in paraguay and worldwide were carried out in order to increase our knowledge about the complex pattern of evolution of this virus in nature. paraguayan strains bearing the p[8] genotype were grouped in the lineages p[8]-1, p[8]-2, and p[8]-3. regardless of the year of detection, all of the g4 and g9 strains were related to lineage p[8]-3, whereas the g1 strains were related to the three lineages detected in pa ... | 2008 | 18463781 |
| estimates of the economic burden of rotavirus-associated and all-cause diarrhoea in vellore, india. | to determine the cost of rotavirus and all-cause diarrhoea in vellore, india. | 2008 | 18466182 |
| norovirus genotype iib associated acute gastroenteritis in india. | in india the role of noroviruses in causing gastroenteritis is not well defined. | 2008 | 18467163 |
| characteristics of an ideal rotavirus vaccine. | rotavirus gastroenteritis primarily affects children younger than 5 years of age and is the leading cause of diarrhea-related hospitalizations worldwide. the substantial morbidity associated with this disease and the major burden on healthcare resources underscore the need for an effective vaccine. two recently developed vaccines (rotateq [rotavirus vaccine, live, oral, pentavalent], and rotarix [rotavirus vaccine, live]) share some characteristics of an ideal rotavirus vaccine. high efficacy, e ... | 2008 | 18467670 |
| adenovirus, calicivirus and astrovirus detection in fecal samples of hospitalized children with acute gastroenteritis from campo grande, ms, brazil. | we analyzed fecal samples from hospitalized children up to three years of age with acute gastroenteritis at campo grande, mato grosso do sul, brazil, from may 2000-january 2004. astrovirus and calicivirus were detected by reverse transcription-polymerase chain reaction and adenovirus was detected using the rotavirus and adenovirus combined immunoenzyme assay. astrovirus, adenovirus and calicivirus were detected at rates of 3.1%, 3.6% and 7.6%, respectively. these results re-emphasize the need fo ... | 2008 | 19057829 |
| diversity of human rotavirus g and p genotypes in panama, costa rica, and the dominican republic. | in this study 2,089 fecal samples from patients with gastroenteritis were analyzed from different hospitals in panama, costa rica, and the dominican republic during the period comprised between december 2002 and july 2003. one hundred samples per country from the positives to the enzyme-linked immunosorbent assay (elisa) kit were analyzed by reverse transcription-polymerase chain reaction (rt-pcr) to determine the g and p genotypes: in panama, costa rica, and dominican republic the combinations ... | 2008 | 19052306 |
| rotateq: a three-dose oral pentavalent reassortant rotavirus vaccine. | rotavirus (rv) is a leading cause of diarrhea worldwide, and will infect every child by their 5th birthday. the 3-dose oral pentavalent rv vaccine (rotateq), consisting of serotypes g1, g2, g3, g4 and p1a[8], was licensed in the usa in 2006. the first dose should be administered between the ages of 6 and 12 weeks and the third dose should be given before the age of 32 weeks (usa) or 26 weeks (europe). in a large clinical trial, the vaccine prevented 74% of cases of rv gastroenteritis, and 98% of ... | 2008 | 19053204 |
| active, population-based surveillance for severe rotavirus gastroenteritis in children in the united states. | routine vaccination of us infants against rotavirus was implemented in 2006, prompting the centers for disease control and prevention new vaccine surveillance network to begin population-based acute gastroenteritis surveillance among us children<3 years of age. this surveillance system establishes baseline estimates of rotavirus disease burden and allows for the prospective monitoring of rotavirus vaccination impact. | 2008 | 19047240 |
| [infectional and molecular-genetical properties of cryopreserved strains of adeno- and rotaviruses]. | influence of cryopreservation and long-term storage in conditions of moderate-low temperatures on infectious activity and molecular-genetic properties of monkey rotavirus, human family rotavirus and human adenovirus of serotype 3 has been studied. preservation of initial antigenic structure and biological properties of the given viruses is necessary both in biotechnology for manufacture of means of specific preventive maintenance and diagnostics of human adeno- and rotavirus infection and for pr ... | 2008 | 19044012 |
| [studies on simultaneous detection of four foodborneviruses by multiplex reverse transcription-polymerase chain reaction]. | to establish a method for simultaneous detection of norovirus (nv), rotavirus (rv), astrovirus (av) and hepatitis a virus (hav) by multiplex reverse transcription-polymerase chain reaction (rt-pcr). | 2008 | 19040044 |
| high frequency of rotavirus viremia in children with acute gastroenteritis: discordance of strains detected in stool and sera. | recently, rotavirus antigenemia and viremia have been identified in patients with acute gastroenteritis. this study examined rotavirus viremia in children hospitalized for acute gastroenteritis in order to establish its association with fecal shedding of rotavirus, infecting genotypes and antibody marker of acute infection. thirty-one pairs of stool-serum specimens were collected from november 2004 to february 2005 together with clinical information. all paired specimens were screened for rotavi ... | 2008 | 19040295 |
| emerging viruses in transplantation: there is more to infection after transplant than cmv and ebv. | transplant physicians and surgeons are familiar with the risks, clinical behavior, and management of cytomegalovirus in transplant recipients. donor-transmitted viral infections are uncommon but in recent years have brought to light the clinical manifestations of rabies, west nile virus, and lymphocytic choriomeningitis virus in the early posttransplant period. later posttransplant, infection with viruses circulating in the community can occur with a number of pathogens, including some vaccine-p ... | 2008 | 19033999 |
| defective rotavirus particle assembly in lovastatin-treated ma104 cells. | rotavirus is a non-enveloped virus that depends on cellular lipids for cell entry and associates with lipid rafts during assembly. however, the effects of cellular lipids on rotavirus assembly are still not fully understood. the present study analyzes the effects of lovastatin, an inhibitor of cholesterol biosynthesis, during rotavirus infection in ma104 cells with regard to viral growth and particle assembly. following viral infection, a 2-log relative reduction of viral titers was observed in ... | 2008 | 19030953 |
| [distribution signature analysis between intussusception and rotavirus diarrhea in young children]. | to investigate the annual incidence rate of intussusception over a 5-year period in suzhou and to determine whether there was a potential link between intussusception rotavirus diarrhea. | 2008 | 19031708 |
| comparison of clinical features of childhood norovirus and rotavirus gastroenteritis in taiwan. | viral gastroenteritis is a common acute infectious disease in infants and young children. this study compared the incidence and clinical features of childhood norovirus (nv) and rotavirus (rv) gastroenteritis in taiwan. | 2008 | 19015054 |
| molecular characterisation of a bovine-like rotavirus detected from a giraffe. | rotavirus (rv), is a member of the reoviridae family and an important etiological agent of acute viral gastroenteritis in the young. rotaviruses have a wide host range infecting a broad range of animal species, however little is known about rotavirus infection in exotic animals. in this paper we report the first characterisation of a rv strain from a giraffe calf. | 2008 | 19014526 |
| epidemiological shifts in severe acute gastroenteritis in us children: will rotavirus vaccination change the picture? | 2008 | 19014813 | |
| supplementing suckling rats with whey protein concentrate modulates the immune response and ameliorates rat rotavirus-induced diarrhea. | group a rotaviruses (rv) are the most common causative agents of acute gastroenteritis in children <2 y. the present study was designed to establish the effect of a bovine whey protein concentrate (wpc) in a rv infection model in suckling rats. from d 3 of life, suckling lewis rats received daily supplements of wpc, wpc plus lactoferrin (lf), standard infant formula (sif), or water (rv-infected group and an untreated, uninfected reference group). on d 8 of life, heterologous simian rv sa-11 was ... | 2008 | 19022963 |
| rotavirus surveillance--worldwide, 2001-2008. | rotavirus infection is the leading cause of severe acute diarrhea among young children worldwide. an estimated 527,000 children aged <5 years die from rotavirus diarrhea each year, with >85% of these deaths occurring in low-income countries of africa and asia. two licensed rotavirus vaccines have shown efficacy of 85%-98% against severe rotavirus diarrhea in trials conducted in the americas and europe, and they have been introduced into routine immunization programs in 11 countries in these regi ... | 2008 | 19023263 |
| retrospective study of bovine neonatal mortality: cases reported from inta balcarce, argentina. | a retrospective study was performed on 169 beef and dairy calves aged from 1 to 7 days old submitted to the diagnostic laboratories at inta balcarce, argentina. bacterial culture was performed for aerobic and microaerophilic organisms. samples from spleen and lymph nodes, and peripheral blood mononuclear cells were also cultured for viral isolation on cell culture. bovine rotavirus was detected by direct-elisa. multiple tissue samples were fixed in 10% formalin, routinely processed and stained w ... | 2008 | 19024501 |
| [evaluation of two immunochromatography kits for rapid diagnosis of rotavirus infections]. | a prospective study was conducted to evaluate two immunochromatography (icg) commercial kits for diagnosis of rotavirus infection, vikia rota-adeno (biomérieux) and simple rota-adeno (operon). reverse transcriptase and polymerase chain reaction (rt-pcr) with specific primers for the vp7 gene of group a rotavirus was used as the reference method. the sensitivity and specificity of the icg tests compared with those of the reference method were 98.4% and 84.8%, respectively, for simple rota-adeno ( ... | 2008 | 19024505 |
| global networks for surveillance of rotavirus gastroenteritis, 2001-200. | 2008 | 19024780 | |
| coadministration of rix4414 oral human rotavirus vaccine does not impact the immune response to antigens contained in routine infant vaccines in the united states. | this study was conducted to confirm the absence of immune interference of 2 doses of rix4414 (rotarix) on routine infant vaccinations in the united states. | 2008 | 18977955 |
| burden of rotavirus disease among children visiting pediatric emergency departments in cincinnati, ohio, and oakland, california, in 1999-2000. | we assessed the incidence of rotavirus disease requiring an emergency department visit among children <5 years of age. | 2008 | 18977975 |
| importance of on-time rotateq vaccination and long-term active surveillance. | 2008 | 18977997 | |
| novel vaccines: bridging research, development and production. | vaccines are among the greatest achievements of modern medicine, leading to the eradication of naturally occurring smallpox, the near elimination of polio and the control of diseases such as rotavirus and hepatitis a and b in industrialized countries. conventional vaccines, however, protect against a limited number of infectious diseases and, in some cases, provide incomplete protection. effective vaccines against common infections such as hiv, hepatitis c and malaria remain an unmet medical nee ... | 2008 | 18980535 |
| shifting prevalence of major diarrheal pathogens in patients seeking hospital care during floods in 1998, 2004, and 2007 in dhaka, bangladesh. | bangladesh experienced severe flooding and diarrheal epidemics in 2007. we compared flood data from 2007 with 2004 and 1998 for diarrheal patients attending the icddr,b hospital in dhaka. in 2007, vibrio cholerae o1 (33%), rotavirus (12%), and enterotoxigenic escherichia coli (etec) (12%) were most prevalent. more severe dehydration was seen in 2007 compared with 2004 and 1998 (p < 0.001). in 2007, v. cholerae o1 inaba (52%) and ogawa (48%) were seen, whereas in 2004 and 1998 it was primarily in ... | 2008 | 18981509 |
| funding of drugs: do vaccines warrant a different approach? | vaccines have features that require special consideration when assessing their cost-effectiveness. these features are related to herd immunity, quality-of-life losses in young children, parental care and work loss, time preference, uncertainty, eradication, macroeconomics, and tiered pricing. advisory committees on public funding for vaccines, or for pharmaceuticals in general, should be knowledgable about these special features. we discuss key issues and difficulties in decision making for vacc ... | 2008 | 18992409 |
| 3d jigsaw puzzle in rotavirus assembly. | in this issue of structure, lu et al. (2008) report results of structural and functional analysis of rotavirus rna-dependent rna polymerase, vp1. based on their analyses of vp1 in rna free and bound forms, the authors propose a mechanism for coordinated genome packaging and replication. | 2008 | 19000811 |
| mechanism for coordinated rna packaging and genome replication by rotavirus polymerase vp1. | rotavirus rna-dependent rna polymerase vp1 catalyzes rna synthesis within a subviral particle. this activity depends on core shell protein vp2. a conserved sequence at the 3' end of plus-strand rna templates is important for polymerase association and genome replication. we have determined the structure of vp1 at 2.9 a resolution, as apoenzyme and in complex with rna. the cage-like enzyme is similar to reovirus lambda3, with four tunnels leading to or from a central, catalytic cavity. a distingu ... | 2008 | 19000820 |
| biometric fingerprinting for visa application: device and procedure are risk factors for infection transmission. | biometric fingerprint identity verification is currently introduced in visa application and entry screening at border control. the system implies physical contact between the skin and the surface of the fingerprint-capturing and reading devices. | 2008 | 19006507 |
| inactivated rotavirus vaccines: a priority for accelerated vaccine development. | live oral rotavirus vaccines have proven to be generally safe and effective to prevent severe dehydrating diarrhea among children in high and some middle income countries. however, concerns linger about rare but severe adverse events, such as intussusception and their efficacy against the full range of rotavirus serotypes. more importantly, live oral vaccines have been less immunogenic and results of trials to assess their efficacy in poor children of both africa and asia will not be available f ... | 2008 | 18951937 |
| immunizations. making progress against rotavirus. | 2008 | 18953698 | |
| evaluating clinical trial data and guiding future research for rotavirus vaccines. | 2008 | 18949859 | |
| purification of recombinant rotavirus vp7 glycoprotein for the study of in vitro rotavirus-like particles assembly. | rotavirus vp7 is a glycoprotein that forms the viral capsid outerlayer and is essential to the correct assembly of triple-layered rotavirus-like particles (rlps). in this work, a novel purification strategy was designed to allow obtaining highly pure monomeric vp7 required for the rlps in vitro assembly. vp7 production kinetics in baculovirus-insect cells at cell concentration at infection (cci) of 1x10(6)cellsml(-1) was compared in terms of vp7/glycoprotein 64 (gp64) ratio at different multipli ... | 2008 | 18805074 |
| prevalence of four enteropathogens in the faeces of young diarrhoeic dairy calves in switzerland. | the prevalences of cryptosporidium parvum, rotavirus, bovine coronavirus (bcv), and enterotoxigenic escherichia coli (e coli k99) were determined in diarrhoeic dairy calves aged one to 21 days on 71 dairy farms in western switzerland during the winter of 2005 to 2006. faecal samples from 147 untreated calves suffering from acute diarrhoea were analysed by standardised diagnostic methods, and the immunoglobulin status of each calf was evaluated. the prevalences of c parvum, rotavirus, bcv and e c ... | 2008 | 18806281 |
| an outbreak of group a rotavirus g1p[8] in an elementary school, nara prefecture. | 2008 | 18806362 | |
| use of vsl[sharp]3 in the treatment of rotavirus diarrhea in children: preliminary results. | we conducted a double-blind randomized placebo-controlled study to evaluate efficacy and tolerability of vsl[sharp]3 (cd pharma india) in the treatment of acute rotavirus diarrhea in children. the patients were randomly assigned to receive 4 days of oral treatment with vsl[sharp]3 probiotic mixture or placebo in addition to usual care for diarrhea. results: out of 230 rotavirus-positive acute diarrhea children, 224 children completed the study, (113 in the drug group and 111 in the placebo group ... | 2008 | 18806703 |
| [infectious diseases in poland in 2006]. | over last decade problem of infectious diseases in poland remains stable with trends of decreasing incidence of most reported infectious diseases. in particular there was observed decrease in incidence of tuberculosis and foodborne infections causes by salmonella sp. on the other hand it was observed increase of reported foodborne infections caused by campylobacter and yersinia as well and viral ones caused by noroviruses and rotaviruses. despite marked increase of diagnosed and reported cases s ... | 2008 | 18807459 |
| rotavirus vaccines: viral shedding and risk of transmission. | rotavirus causes gastroenteritis in almost all children by 5 years of age. immunity to rotavirus is incomplete, with potential for recurrent infections occurring throughout life. live rotavirus vaccines have been developed for the protection of children from severe wildtype rotavirus infections. transmission of vaccine virus strains from vaccinated children to unvaccinated contacts harbours the potential for herd immunity, but also the risk of vaccine-derived disease in immunocompromised contact ... | 2008 | 18922486 |
| clinical characteristics of nosocomial rotavirus infection in children in taiwan. | the aim of this study was to determine the incidence and clinical characteristics of nosocomial rotavirus infection (nri) among hospitalized children. | 2008 | 18926946 |
| closing the diarrhoea diagnostic gap in indian children by the application of molecular techniques. | a large proportion of diarrhoeal illnesses in children in developing countries are ascribed to an unknown aetiology because the only available methods, such as microscopy and culture, have low sensitivity. this study was aimed at decreasing the diagnostic gap in diarrhoeal disease by the application of molecular techniques. faecal samples from 158 children with and 99 children without diarrhoea in a hospital in south india were tested for enteric pathogens using conventional diagnostic methods ( ... | 2008 | 18927413 |
| [afebrile convulsions associated to rotavirus]. | 2008 | 18928714 | |
| [incorporation of varicella-zoster virus vaccination in childhood immunization schedules]. | varicella is a highly infectious disease caused by the varicella-zoster virus (vzv). usually chickenpox is a self-limiting and relatively mild disease of childhood, although it is frequently more severe with significant complications, and less often, is responsible for case fatalities. varicella disease is more severe and its complications are more frequent and severe amongst high risk groups (neonates, pregnant women and immunocompromised patients). after the initial infection, the vzv remains ... | 2008 | 18935757 |
| [virus removal in conventional wastewater treatment process]. | little has been published in the scientific literature on the distribution of pathogenic viruses and on their removal in the different treatment phases in wastewater treatment plants in italy. recent advances in molecular biology have reduced analytic costs and allowed the detection of virus directly in the environment. this study evaluates the presence of enteric viruses and their removal in three treatment plants of different sizes and which use different treatment methods. overall 92 samples ... | 2008 | 18936796 |
| effect of rotavirus on serum tacrolimus level in pediatric liver transplant recipients. | 2008 | 18937762 | |
| [rotavirus vaccine]. | rotavirus gastroenteritis is one of the most important diseases in young children. there are 400,000 to 600,000 deaths annually among children under 5 years old in the world, especially in developing countries. rotavirus vaccine has been developed since 1980s. however vaccine development and trial took a long time before the commercial available. one reason is the genetic variability of rotavirus, there are more than 10 serotypes (g types) in group a rotavirus. another reason is side reaction su ... | 2008 | 18939500 |
| aetiology of community-acquired, acute gastroenteritis in hospitalised adults: a prospective cohort study. | the aetiology of severe gastroenteritis leading to hospitalisation in adults frequently remains unclear. our objective was to study the causes and characteristics of community-acquired, acute gastroenteritis in adult hospitalized patients to support the clinical management of these patients. | 2008 | 18940017 |
| mathematical models of cervical cancer prevention in latin america and the caribbean. | using population and epidemiologic data for 33 countries in latin america and the caribbean (lac), a model-based approach estimated averted cervical cancer cases and deaths, disability-adjusted life years (dalys) and incremental cost-effectiveness ratios (i$/daly averted) for human papillomavirus (hpv) vaccination of young adolescent girls. absolute reduction in lifetime cancer risk varied between countries, depending on incidence, proportion attributable to hpv-16 and 18, and population age-str ... | 2008 | 18945403 |
| human papillomavirus vaccine policy and delivery in latin america and the caribbean. | cervical cancer caused by human papillomavirus (hpv) is a major preventable public health problem. two vaccines are now available for primary prevention of hpv infection and their introduction offers new opportunities to enhance comprehensive cervical cancer prevention and control. currently, hpv vaccine price is a significant barrier to rapid vaccine introduction and access. therefore, making evidence-based decisions about whether and how to introduce hpv vaccine into the immunization schedule ... | 2008 | 18945405 |
| phylogenetic analysis of rotaviruses with genotypes g1, g2, g9 and g12 in bangladesh: evidence for a close relationship between rotaviruses from children and adults. | to clarify the phylogenetic relatedness of rotaviruses causing gastroenteritis in children and adults, an epidemiologic investigation was conducted in mymensingh, bangladesh, during the period between july 2004 and june 2006. a total of 2,540 stool specimens from diarrheal patients from three hospitals were analyzed. overall, rotavirus-positive rates in children and adults were 26.4 and 10.1%, respectively. among the 155 rotavirus specimens examined genetically from both children and adults, the ... | 2008 | 18839059 |
| functional mx protein does not prevent experimental biliary atresia in balb/c mice. | biliary atresia (ba) is a rare cholestatic disease, which manifests itself in the form of inflammation of the liver and bile ducts in newborns, with an unknown etiology and a poor outcome. mx proteins, which are mediators of innate, antiviral resistance induced by type i interferon, were recently detected in the livers of children with ba. therefore, the aim of this study was to examine whether the expression of mx protein could affect the course of experimental ba in mice. a total of 185 newbor ... | 2008 | 18841540 |
| aichi virus, norovirus, astrovirus, enterovirus, and rotavirus involved in clinical cases from a french oyster-related gastroenteritis outbreak. | following a flooding event close to a shellfish production lagoon, 205 cases of gastroenteritis were linked to oyster consumption. twelve stool samples from different individuals were collected. analysis showed that eight samples were positive for multiple enteric viruses, and one stool sample had seven different enteric viruses. analysis of shellfish implicated in the outbreak allowed detection of the same diversity of enteric viruses, with some viral genomic sequences being identical to those ... | 2008 | 18842942 |
| epidemiology, clinical presentations and burden of rotavirus diarrhea in children under five seen at ramathibodi hospital, thailand. | to be able to monitor the impact of rotavirus vaccines in the future, the authors designed the present study along with the rotavirus surveillance project-thailand. | 2008 | 18843863 |
| microbiological and epidemiological aspects of rotavirus and enteric adenovirus infections in hospitalized children in italy. | rotaviruses and enteric adenoviruses are the most important causative agents of acute infantile gastroenteritis worldwide. from july 2005 to june 2007, 445 stool specimens from pediatric patients hospitalized with acute diarrhea were collected and tested for the presence of rotaviruses and enteric adenoviruses using an immunochromatographic assay. rotavirus infection was detected in 123 cases (27.6%, ranging from 31.7% in 2005-2006 to 24.2% in 2006-2007); adenovirus infection occurred in 17 case ... | 2008 | 18843886 |
| [outbreak of rotavirus diarrhea among children in funing county]. | 2008 | 18844005 | |
| [molecular detection of shiga toxin-producing (stx1) escherichia coli and rotavirus in stools of children with diarrhea]. | the presence of e. coli producer of shiga toxin and rotavirus was investigated in 90 stool samples from children less than 3 years old with diarrhea. three aliquots were separated from each sample: the first one underwent previous enrichment for e. coli o157, the second one was plated on agar macconkey-sorbitol and red eosine with mug, and the last one was frozen at -70 degrees c for the later analysis of rotavirus. the search of the antigen o157 of e. coli was carried out by immunochromatograph ... | 2008 | 18846778 |
| next generation of human vaccines: what does the future hold? | the world vaccine congress was held in arlington, va april 21st-24th, 2008. tevi troy, the deputy secretary of the us department of health and human services, set the tone of the meeting during his keynote address. he discussed the government's plan to deliver a strategic outlook and follow a road map for vaccine development. he also emphasized the importance of ongoing cooperation between industry and the government's many departments. in an electrifying keynote address gregory poland, professo ... | 2008 | 18849649 |
| protein profile and morphometry of cultured human blastocystis hominis from children with gastroenteritis and healthy ones. | a total of 180 children of age group 5-12 years old in both sexes, of whom 90 were symptomatic and negative for other parasites, rotavirus or pathogenic bacteria. another 90 children were asymptomatic, but with b. hominis in stools. direct smear, formaline-ethyl acetate sedimentation concentration, kinyon carbol-fuchin stain, stool culture, enzyme immunoassay, culturing, morphometric study, gel electrophoresis and experimental infection of mice were done. the results showed that the central body ... | 2008 | 18853619 |
| trends in healthcare usage attributable to diarrhea, 1995-2004. | to determine current diarrhea-associated healthcare usage rates and associated sociodemographic factors. these data can be used to determine the impact of the rotavirus vaccine. | 2008 | 18692199 |
| rotavirus vaccine for developing countries. | 2008 | 18692705 | |
| rotavirus vaccine for developing countries. | 2008 | 18692706 | |
| changing distribution of human rotavirus serotypes during two epidemic outbreaks of gastroenteritis in campinas, são paulo, brazil, 2003-2004: detection of g6 strains. | rotavirus serotypes g1-g4 and g9 are the most important agents of severe diarrhea in children worldwide. | 2008 | 18693133 |
| evaluation of ifn-gamma response to rotavirus and non-structural protein nsp4 of rotavirus in children following severe rotavirus diarrhea. | rotavirus (rv) is the commonest cause of severe gastroenteritis in young children worldwide. however the natural immune mechanisms controlling and preventing rotavirus disease in humans are not fully understood. | 2008 | 18693134 |
| immunogenicity, reactogenicity and safety of a diphtheria-tetanus-acellular pertussis-inactivated polio and haemophilus influenzae type b vaccine in a placebo-controlled rotavirus vaccine study. | in recent years, acellular pertussis combination vaccines have facilitated compliance with and coverage of the national immunisation programme in singapore. this phase-ii study (rota-007) evaluated the immunogenicity, reactogenicity and safety of a dtpa-ipv/hib combined vaccine when co-administered with a rotavirus vaccine. | 2008 | 18695765 |
| genetic characterization of group c rotavirus isolated from a child hospitalized with acute gastroenteritis in chiang mai, thailand. | during an epidemiological survey of human rotavirus infection in chiang mai, thailand, from 2002 to 2004, in which 263 stool specimens tested, one isolate of group c rotavirus was detected from a two-year-old child admitted to hospital with acute gastroenteritis. the human group c rotavirus, named cmh004/03, was characterized further by molecular analyses of its vp4, vp6, and vp7 gene segments as well as determination of rna pattern by polyacrylamide gel electrophoresis (page). molecular charact ... | 2008 | 18696224 |
| detection of a porcine-like rotavirus in a child with enteritis in italy. | during a 1-year rotavirus surveillance of children hospitalized with acute gastroenteritis in brescia hospital, italy, a chimerical rotavirus strain, g3p[6], was detected, displaying the vp7 and vp4 genes of porcine origin and the nsp4 and vp6 genes of human origin. the reassortant nature of the virus rules out a direct zoonotic event. | 2008 | 18701665 |
| abnormal computed tomography findings among children with viral gastroenteritis and symptoms mimicking acute appendicitis. | to evaluate computed tomography (ct) findings in pediatric patients with viral gastroenteritis who presented with clinical features of acute abdomen. | 2008 | 18703990 |
| evidence of intrafamilial transmission of rotavirus in a birth cohort in south india. | transmission of rotavirus infection was studied in a birth cohort of children based in an urban slum in vellore and their familial contacts. contemporaneous samples from index patients and their familial contacts were collected for analysis in three different settings. firstly, samples were collected from familial contacts during a period of rotavirus infection in children from the cohort. secondly, on occasions when a family member had rotavirus diarrhea, samples from the cohort child were take ... | 2008 | 18712810 |
| molecular characterization of enteric viral agents from children in northern region of ghana. | viral gastrointestinal infections are among the most important causes of childhood morbidity and mortality, especially in non-industrialized countries. the objective of this study was the molecular characterization of rotaviruses, noroviruses, adenoviruses, astroviruses, and enteroviruses obtained from 367 children in the northern region of ghana. one hundred and forty-two rotavirus-positive stool samples were examined. the most frequent type identified was g1p[8] occurring in 80% of the cases. ... | 2008 | 18712819 |
| molecular characterization of equine rotavirus in ireland. | group a rotaviruses are important causative agents of severe, acute dehydrating diarrhea in foals. a total of 86 rotavirus-positive fecal samples, collected from diarrheic foals from 11 counties in three of the four provinces of ireland, were obtained from the irish equine centre in kildare during a 7-year (1999 to 2005) passive surveillance study and were characterized molecularly to establish the vp7 (g type) and vp4 (p type) antigenic specificities. fifty-eight samples (67.5%) were found to c ... | 2008 | 18716232 |
| randomized double blinded controlled trial to evaluate the efficacy and safety of bifilac in patients with acute viral diarrhea. | to evaluate the efficacy and safety of bifilac on reducing the episodes (frequency) and duration of diarrhea induced by rotaviral infection and to evaluate the efficacy of bifilac to ameliorate the associated symptoms like dehydration and duration of rotaviral shedding in faeces. | 2008 | 18716740 |
| a new rotavirus vaccine. | 2008 | 18719524 | |
| the post-tsunami outbreak of diarrhoeal diseases in car nicobar island, india, was caused by human group a rotavirus g2 strains. | 2008 | 18723226 | |
| consensus recommendations on immunization, 2008. | justification: there is a need to formulate recommendations regarding use of new vaccines which have become recently available/will soon be available and to review/revise recommendations about existing vaccines in light of recent information. | 2008 | 18723905 |
| detection of human enteric viruses in japanese clams. | a total of 57 clam packages that were collected from supermarkets and fish markets from 11 different sites in western japan between 8 december 2005 and 6 september 2006 were examined for human enteric viruses (i.e., norovirus, aichi virus, rotavirus, adenovirus, hepatitis a virus, and astrovirus), using pcr and reverse transcription pcr. sixty-one percent of the packages were contaminated with one type of virus, 9% had two different types of viruses, 28% had three different types of viruses, and ... | 2008 | 18724766 |
| the influence of cd4+ cd25+ foxp3+ regulatory t cells on the immune response to rotavirus infection. | rotavirus (rv) infection of the intestine is the major cause of severe dehydrating diarrhea in infants around the world. although protective immunity against rv, especially acquired b and t-cell responses, has been extensively studied, our understanding of rv immunity remains incomplete. in addition, the interaction between various protective immune mechanisms in the gut and specific enteric immune suppressor systems that normally exert a regulatory function on mucosal immunity has not been exte ... | 2008 | 18725261 |
| progress in understanding norovirus epidemiology. | noroviruses are now recognized as important causes of illness, and their incidence, impact, or both appear to have changed in recent years. this review focuses on studies that provide new knowledge needed to understand their transmission, pathogenesis, evolutionary changes and options for control. | 2008 | 18725806 |
| why does the world need another rotavirus vaccine? | a "meeting on upstream rotavirus vaccines and emerging vaccine producers" was held at the world health organization in geneva, switzerland on march 28-30, 2006. the purpose was to discuss, evaluate, and weigh the importance of additional rotavirus vaccine candidates following the successful international licensure of rotavirus vaccines by two major pharmaceutical companies (glaxosmithkline and merck) that had been in development for many years. both licensed vaccines are composed of live rotavir ... | 2008 | 18728720 |
| increase in prevalence of human group a rotavirus g9 strains as an important vp7 genotype among children in eastern india. | in addition to four globally important group a rotavirus (garv) vp7 genotypes (g1-g4), recent surveillance studies have revealed importance of g9 strains as an aetiological agent of infantile diarrhoea. | 2008 | 18755625 |
| concomitant use of the oral pentavalent human-bovine reassortant rotavirus vaccine and oral poliovirus vaccine. | the live oral pentavalent rotavirus vaccine (prv) is well tolerated and highly efficacious against rotavirus gastroenteritis. this open-label, multicenter study evaluated the immunogenicity and safety of coadministering oral poliovirus vaccine (opv) with prv. | 2008 | 18756184 |
| severe clostridium difficile-associated disease in children. | three cases of clostridium difficile-associated disease in children were detected within a short time interval. intensive therapy was required in 2 cases with colectomy in one of them. one of the severe cases was community-acquired. two patients had underlying diseases (hirschprung disease, down syndrome) and also tested positive for enteric viruses (rotavirus, calicivirus). | 2008 | 18756189 |
| [rotaviruses "target" infants, noroviruses for seniors]. | 2008 | 18757038 | |
| electrophoretic rna genomic profiles of rotavirus strains prevailing among hospitalized children with acute gastroenteritis in tehran, iran. | human rotavirus has now been established as the most important cause of childhood gastroenteritis worldwide. the rna genomic electrophoretic diversity of group a rotavirus strains in tehran, iran, during april 2002 through march 2005, was investigated in 1250 stool specimens. | 2008 | 18759520 |
| survey of rotavirus surveillance, laboratory capacity and disease burden in the eastern part of the who european region. | following the licensure of two rotavirus vaccines in europe, we aimed to assess factors, such as surveillance, disease burden and laboratory capacity, which will be relevant for making decisions about rotavirus vaccine introduction in the different countries. we conducted an email-based survey of the national public health bodies in the world health organization (who) european region in 2006 and report here the results from the 23 countries in the eastern part of the region. the survey included ... | 2008 | 18761887 |
| one-step quantitative rt-pcr for the detection of rotavirus in acute gastroenteritis. | the standard diagnosis of rotavirus gastroenteritis is based on the demonstration of rotavirus antigen in stools using an enzyme immunoassay (eia). in this study, a one-step quantitative rt-pcr (q-pcr) was used for sensitive detection of rotavirus in diarrheal stools. the primers and taqman probe for the q-pcr were selected from a highly conserved region of the non-structural protein 3 (nsp3) of rotavirus. after validation, the test was applied to study rotavirus eia positive (n=25) and eia nega ... | 2008 | 18765254 |