| polymicrogyria in a fetus with human parvovirus b19 infection: a case with radiologic-pathologic correlation. | we report the prenatal magnetic resonance imaging (mri) appearance of polymicrogyria with pathologic correlation in a fetus with congenital parvovirus b19 infection. prenatal ultrasound revealed non-immune hydrops, but detected no fetal brain abnormalities. a subsequent fetal mri scan performed at 23 weeks' gestation demonstrated bilateral polymicrogyria, which was confirmed at autopsy. to our knowledge, prenatal diagnosis of polymicrogyria in association with congenital parvovirus b19 infection ... | 2012 | 22344957 |
| inactivation and neutralization of parvovirus b19 genotype 3. | parvovirus b19 (b19v) is a common contaminant of human plasma donations. three b19v genotypes have been defined based on their dna sequence. reliable detection of genotype 3 dna has proved problematic because of unexpected sequence variability. b19v genotype 3 is found primarily in west africa, but was recently detected in plasma from a north american donor. the safety of plasma-derived medicinal products, with respect to b19v, relies on exclusion of high-titer donations, combined with virus cle ... | 2012 | 22339291 |
| parvovirus b19 and necrotizing enterocolitis in neonates. | | 2012 | 22316626 |
| significant association of past parvovirus b19 infection with cytopenia in both adult-onset still's disease and systemic lupus erythematosus patients. | human parvovirus b19 (b19) infection has been reported as a possible cause of autoimmune diseases. the association of b19 infection with adult-onset still's diseases (aosd) remains unclear. | 2012 | 22309679 |
| reactive haemophagocytic syndrome associated with parvovirus b19 in a kidney-pancreas transplant patient. | | 2012 | 22294016 |
| virus infection of the heart--unmet therapeutic needs. | for over 50 years, viral infection has been recognized as an important trigger of acute myocarditis, inflammatory dilated cardiomyopathy (dcm) and congestive heart failure. nevertheless, viral heart disease remains challenging to diagnose and treat. improved diagnostic methods for myocarditis have led to a better understanding of its pathophysiology. the recognition of virus-mediated damage, inflammation and autoimmune dysregulation in these patients highlights the importance of differentiating ... | 2012 | 22293868 |
| genotyping of human parvovirus b19 among brazilian patients with hemoglobinopathies. | human parvovirus b19 (b19v) infection can be a life-threatening condition among patients with hereditary (chronic) hemolytic anemias. our objective was to characterize the infection molecularly among patients with sickle cell disease and thalassemia. forty-seven patients (37 with sickle cell disease, and 10 with β-thalassemia major) as well as 47 healthy blood donors were examined for b19v infection by anti-b19v igg enzyme immunoassay, quantitative pcr, which detects all b19v genotypes, and dna ... | 2012 | 22280886 |
| serological and virological analysis of maternal and fetal blood samples in prenatal human parvovirus b19 infection. | intrauterine parvovirus b19 (b19v) infection can be asymptomatic or may cause severe fetal complications. information on serological and virological findings of infection in the fetus is scarce. | 2012 | 22275404 |
| parvovirus b19 in pregnancy: prenatal diagnosis and management of fetal complications. | parvovirus b19 infection is often considered a mild and self-limiting disease of minor clinical importance. this review aims to raise awareness of recently discovered potentially devastating consequences of this infection in pregnancy, and provides updated guidelines on diagnosis and management. | 2012 | 22249146 |
| acute liver failure as the initial manifestation of wilson disease triggered by human parvovirus b19 infection. | | 2012 | 22217972 |
| acute heart failure caused by parvovirus b-19 myocarditis treated with human immunoglobulin. | we describe the case of a 42-year-old woman developing cardiogenic shock with cardiac tamponade due to an acute myo-pericarditis caused by parvovirus b19 (pvb19), successfully treated with intravenous (iv) immunoglobulin administration. | 2012 | 24826236 |
| [the diagnostic value of virus serology in patients with non-ischemic systolic heart failure and parvovirus b19 infection]. | we determined retrospective analysis of the diagnostic value of virus serology in patients with non-ischemic systolic heart failure and parvovirus b19 infection. | 2012 | 23654140 |
| pure red cell aplasia caused by ribavirin and interferon treatment. | anemia is a common complication of hepatitis c (hcv), and antiviral treatment can further increase this risk. we present the case of a 59-year-old man with hcv treated with ribavirin and pegylated interferon alpha (inf-α) who presented with severe anemia. two months after initiating treatment his hemoglobin dropped from 14.2 to 5.0 g/dl. there was no evidence of bleeding or hemolysis, and a bone marrow biopsy revealed pure red cell aplasia (prca). evaluations for acute cytomegalovirus and parvov ... | 2011 | 26189631 |
| parvovirus-b19 and hematologic disorders. | parvovirus-b19 (pv-b19) is a member of parvoviridae, which is one of the smallest dna viruses. pv-b19-associated diseases usually serve as a good representation of the balance of virus, host response and the immune system. the diseases manifested with pv-b19 are erythema infectiosum, which is common in children, hydrops fetalis, transient pure red cell aplasia in patients with chronic hemolytic anemia, arthralgia - mostly observed in women, and chronic pure red cell aplasia in immunocompromised ... | 2010 | 27263735 |
| parvovirus b19 during pregnancy: a review. | several infections in adults warrant special consideration in pregnant women given the potential fetal consequences. among these is parvovirus b19 deserves special attention since the harmful effects on the pregnant woman and fetus. it can then cause fetal anemia, non-immune fetal hydrops and fetal death. among cases with fetal demise, b19 is foundin significant numbers, especially in the second andthird trimesters of pregnancy. there is no specific treatment or prophylaxis available against b19 ... | 2010 | 22439064 |
| diagnosis of in utero parvovirus b19 infection and maternal immune response - the relevance of linear epitopes and advanced serologic testing. | parvovirus b19 (b19v) infection in utero causing fetal anemia and non-immune hydrops fetalis (nihf) is a potentially life-threatening event for the fetus. postexpositional non-invasive diagnosis is based on maternal igg/igm response and detection of viral genome in maternal blood. serologic testing directs prenatal follow-up. fetal infection is confirmed by polymerase chain reaction or in situ hybridization in fetal blood and/or amniotic fluid cells. the performance of serologic tests is signifi ... | 2010 | 23484447 |
| seroprevalence of erythrovirus b19 igg among saudi blood donors in makkah, saudi arabia. | to determine the seroprevalence of immunoglobulin g (igg) to erythrovirus b19 in saudi blood donors in makkah. saudi arabia. | 2009 | 23012201 |
| acute liver failure and myelosuppression due to parvovirus b19 infection: a case report. | parvovirus b19 has been associated with different diseases, such as erythema infectiosum, arthropathy and transient aplastic crisis. however, parvovirus b19 infection presenting as hepatic dysfunction and myelosuppression is rarely reported in adult patients. herein, we report an adult case of acute parvovirus b19 infection presented with acute liver failure and myelosuppression. after being treated with gamma globulin, the patient's liver function and bone marrow test improved. we conclude that ... | 2009 | 27956964 |
| [parvovirus b19 and pregnancy]. | | 2008 | 18501291 |
| prevalence of antibodies to human parvovirus b19 in saudi women of childbearing age in makkah. | to determine the seroprevalence rate of immunoglobulin g (igg) and immunoglobulin m (igm) to parvovirus b19 in pregnant saudi women in makkah. | 2007 | 23012138 |
| parvovirus b19 infection presenting as pre-b-cell acute lymphoblastic leukemia: a transient and progressive course in two children. | parvovirus b19 is the causative agent of various forms of hematologic diseases such as aplastic crisis in patients with hemolytic anemia, aplastic anemia, hypoplastic anemia, and idiopathic thrombocytopenic purpura. in addition, parvovirus b19 infection may precede or be associated with acute lymphoblastic leukemia (all). the authors present two cases of parvovirus b19 infection and bone marrow infiltration with pre-b-cell lymphoblasts; one patients was diagnosed as having all, and the other pat ... | 2004 | 27811615 |
| human parvovirus b19 infection mimicking systemic lupus erythematosus. | abstract although several recent reports have discussed the similarities between human parvovirus b19 (hpv-b19) infection and systemic lupus erythematosus (sle), the relationship between these conditions has not been established owing to the small number of patients investigated. in 1998-1999, an outbreak of erythema infectiosum occurred close to our hospital, enabling us to investigate the clinical, hematological, and serological findings, including serum complement and antinuclear antibodies ( ... | 2001 | 24383775 |
| could parvovirus b19 induce a rejection after bone marrow transplantation in a patient with diamond-blackfan anemia? | a four year-old-girl with diamond-blackfan anemia (dba) that was resistant to corticosteroid treatment and transfusion dependent underwent (bone marrow transplantation) bmt from hla identical sibling. the patient was conditioned with busulfan and cyclophosphamide and achieved complete marrow engraftment and mixed chimerism in dna analysis. for the following 13 months she was not transfusion dependent and had a 100% karnofsky score. but on the 14th month she had anemia ollowing fever, rash and en ... | 2000 | 27263505 |
| serological and virological markers of human parvovirus b19 infection in patients with haemophilia. | clotting factor concentrates prepared from human plasma are a potential route of parvovirus b19 (b19) infection in patients with coagulation disorders. however, it is not clear whether b19 transmits and persistently infects patients with haemophilia, especially those with hiv infection. we examined serological and virological markers of b19 in samples from 40 patients with haemophilia who had been receiving several brands of clotting factor concentrates. all of them were anti-b19 igg seropositiv ... | 1997 | 27214724 |
| seroprevalence of immunoglobulin g antibody to parvovirus b19 in ontario. | the prevalence of antibody to parvovirus b19 was assessed in two populations. in a group of 494 residents from ontario and the maritimes, virus-specific immunoglobulin (ig) m antibody, a marker of acute infection, was found throughout the year but was most prevalent during the late winter and early spring months. the overall prevalence of igg antibody in this group was 30.3%. in an effort to examine age-specific prevalence in this population, a second group of sera from 210 pediatric patients at ... | 1996 | 22514456 |
| association of prenatal closure of the foramen ovale and fetal parvovirus b19 infection in hydrops fetalis. | stenosis of the foramen ovale was found at autopsy in a preterm hydropic female who died 3 hours after birth. subsequently, fetal infection by the human parvovirus b19 was diagnosed by serology collected at autopsy and by identifying the viral genome in both the placenta and autopsy liver by polymerase chain reaction. morphologic findings at autopsy suggested that the disease was in a recovery phase. prenatal closure of the foramen ovale, as an isolated lesion, is a recognized association of fet ... | 2015 | 25850908 |
| brachial neuritis after human parvovirus b19 infection. | this case report presents the clinical picture of a patient with brachial neuritis who was investigated and found to have infection with human parvovirus b19. the clinical presentations and prevalence of human parvovirus infection are discussed, as is the prognosis for brachial neuritis. it is recommended that viral serologic testing, including that for human parvovirus, be carried out in cases of brachial neuritis. (j shoulder elbow surg 1993;2:321-3). | 1993 | 22971793 |
| characterization of antibodies in human immunoglobulin products from different regions worldwide. | the antibody levels against a broad spectrum of pathogens were assessed in commercial intravenous immunoglobulin (ivig) manufactured from pooled plasma obtained from different global regions. | 2021 | 33524620 |