Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| hpv infection among a population-based sample of sexual minority women from usa. | sexual minority women are at risk for infection with human papillomavirus (hpv); yet, relatively little is known about the prevalence of hpv infection among this population. | 2017 | 27165699 |
| cancer stem cells: radioresistance, prediction of radiotherapy outcome and specific targets for combined treatments. | inactivation of cancer stem cells (cscs) is of utmost importance for tumor cure after radiotherapy. an increasing body of evidence complies with a higher radioresistance of cscs compared to the mass of tumor cells, supporting the use of csc related biomarkers for prediction of radiotherapy outcome. treatment individualization strategies for patient groups with vastly different risk of recurrence will most likely require application of more than one biomarker. specifically, inclusion of establish ... | 2017 | 26877102 |
| a randomized intervention study to evaluate whether electronic messaging can increase human papillomavirus vaccine completion and knowledge among college students. | to evaluate an intervention aimed at increasing human papillomavirus (hpv) vaccine completion of the 3-dose series and knowledge. | 2017 | 26821923 |
| bax and bak expression in cervical smears of women with low-and high-risk hpv types: a study of 120 cases. | human papillomavirus (hpv) is known to be involved in the carcinogenesis of squamous cells in uterine cervix cancer, mostly by binding and inactivating the p53 and prb tumor suppressor genes. lately, evidence has emerged suggesting that hpv oncoproteins may interact with proteins involved in cellular apoptosis as well. | 2017 | 26811568 |
| human papillomavirus vaccinations. | 2017 | 26813396 | |
| periungual bowen's disease in a 12-year-old boy treated with photodynamic therapy. | bowen's disease (bd) usually occurs on sun-exposed areas in elderly patients. bd rarely occurs in childhood and lesions of the nail unit and periungual area are likely associated with human papillomavirus infection. herein, we report a case of bd presenting on the periungual area in a 12-year-old boy which was successfully treated with two sessions of photodynamic therapy. | 2017 | 26764086 |
| characterization and management of cutaneous side effects related to the immunosuppressive treatment in solid organ recipients. | patients who underwent solid organ transplantation frequently suffer from different skin diseases, as consequence of the immunosuppressive treatment. specific cutaneous side effects such as acne, hypertricosis or other pilosebaceous unit disorders, gingival hyperplasia, purpura or teleangiectasies are commonly associated to immunosuppressive medications. the majority of these conditions are benign, but the aesthetic concern may affect the patient is quality of life and reduce the adherence to th ... | 2017 | 26758664 |
| ifn-β antiproliferative effect and mirna regulation in human papilloma virus e6- and e7-transformed keratinocytes. | human papilloma viruses (hpvs) are the causative agents of cervical cancer although other types of cancers are associated with hpv infection. type i interferons can interfere with hpv e6- and/or e7-dependent transformation and can affect microrna (mirna) expression. cancer cells show a specific pattern of mirna expression and hpvs are able to modulate mirnas expressed in infected cells. keratinocytes transduced with e6 and e7 from mucosal hpv-16 or cutaneous hpv-38 (k16 and k38) were studied to ... | 2017 | 26748726 |
| barriers to uptake of human papilloma virus vaccine in nigeria: a population in need. | 2017 | 26759519 | |
| the clinical development process for a novel preventive vaccine: an overview. | each novel vaccine candidate needs to be evaluated for safety, immunogenicity, and protective efficacy in humans before it is licensed for use. after initial safety evaluation in healthy adults, each vaccine candidate follows a unique development path. this article on clinical development gives an overview on the development path based on the expectations of various guidelines issued by the world health organization (who), the european medicines agency (ema), and the united states food and drug ... | 2017 | 26732191 |
| condyloma acuminata of the bladder in benign prostatic obstruction: case report and review of literature. | condyloma acuminata (ca) is a warty lesion caused by the sexually transmitted human papillomavirus that most commonly affects external genitalia and mucocutaneous junctions. involvement of the urinary tract (ut) is rare. anogenital ca is considered a predisposition for urethral and subsequently bladder involvement. isolated urinary bladder involvement is thought to be due to immunosuppression. a 60-year-old man presented with progressively worsening lower ut symptoms, which culminated in acute u ... | 2017 | 26739208 |
| a rare case of verrucous carcinoma of penis in an human immunodeficiency virus- infected patient. | cancer is a significant cause of morbidity and mortality in human immunodeficiency virus-infected subjects. verrucous carcinoma is a peculiarly slow evolving, but relentlessly expanding variant of epidermoid carcinoma that is extremely reluctant to metastasize. a 60-year-old unmarried male patient presented with urethral discharge of 3 weeks duration. dorsal slit of the prepuce revealed an ulceroproliferative growth measuring 3 cm × 3 cm arising from prepuce and involving glans. biopsy from the ... | 2017 | 26692616 |
| multiple hpv-induced squamous cell carcinomas on the fingers of a patient with systemic lupus erythematosus: a case and review. | human papilloma virus (hpv) infection is documented to be involved in the development of epithelial malignancies, mostly in cervical cancer. systemic lupus erythematosus (sle) patients have an increased prevalence of such an infection. we report the case of a 55-year-old female sle patient who developed multiple in situ squamous cell carcinomas on her fingers, after chronic hpv infection. hpv-33 dna was isolated from the lesions. the purpose of this case presentation is to raise awareness about ... | 2017 | 26674851 |
| cetuximab rechallenge and monotherapy in patients with squamous cell carcinoma of the head and neck. | smokers with squamous cell carcinoma of the head and neck (scchn) have a particularly poor prognosis when compared with human papillomavirus-positive scchn. here, we present case reports of two smokers with scchn treated with cetuximab-based therapy, highlighting the potential benefit of cetuximab before definitive chemoradiotherapy in patients with poor performance status as well as cetuximab rechallenge after progression. we conclude that cetuximab demonstrated notable effectiveness in two pat ... | 2017 | 26668572 |
| cervical cancer prevention in malaysia: knowledge and attitude of undergraduate pharmacy students towards human papillomavirus infection, screening and vaccination in malaysia. | this study was conducted to evaluate knowledge of undergraduate pharmacy students about human papillomavirus infection and their attitude towards its prevention. a cross-sectional survey was conducted in 270 undergraduate pharmacy students using a validated questionnaire to assess knowledge about human papillomavirus infection and cervical cancer and their attitudes towards human papillomavirus vaccines. eighty-one percent of the respondents knew that human papillomavirus is a cause of cervical ... | 2017 | 26661462 |
| salivary detection of human papilloma virus 16 & 18 in pre-malignant and malignant lesions of oral cavity: is it feasible in pakistani context of socio-cultural taboos? | to evaluate salivary detection of hpv-16 & 18 would be feasible and informative biomarker for oral pre-malignant and malignant lesion in our population. | 2017 | 26648995 |
| prevalence of human papillomavirus in oral lichen planus in an iranian cohort. | oral lichen planus (olp) is a chronic inflammatory mucocutaneous disease with female predominance with the potential for malignant transformation. human papillomavirus (hpv) is associated with both malignant and benign disease in the head and neck region. | 2017 | 26604492 |
| human papillomavirus vaccine initiation among 9-13-year-olds in the united states. | the quadrivalent and 9-valent human papillomavirus (hpv) vaccines are licensed for administration among 9-26-year-old males and females, with routine vaccination recommended for 11-12-year-olds. despite the availability of the vaccine at younger ages, few studies have explored vaccine uptake prior to age 13, and national hpv vaccination surveillance data is limited to 13-17-year-olds. our objective was to examine rates and predictors of hpv vaccine initiation among 9-13-year-olds in the united s ... | 2017 | 26594616 |
| human papillomavirus infection and vaccination. | human papillomavirus (hpv) is an infection that can be sexually transmitted and result in health consequences including genital warts and cancers. two vaccines, gardasil® [human papillomavirus quadrivalent (types 6, 11, 16, and 18) vaccine, recombinant] and cervarix™ [human papillomavirus bivalent (types 16 and 18) vaccine], have been approved for the prevention of hpv and hpv-related diseases. | 2017 | 26586310 |
| human papillomavirus (hpv) detection in cytologic specimens: similarities and differences of available methodology. | accumulating evidence regarding the causative role of human papillomavirus (hpv) in a wide range of malignant and nonmalignant diseases highlights the importance of hpv testing. this study describes and discusses the efficacy and characteristics of 4 well-established and commercially available tests. here, 181 cytologic specimens from cervical smears were analyzed using the hpv sign pq (diatech) and the linear array (roche) method. discrepant results were further studied with the real time high- ... | 2017 | 26580098 |
| significance of human papillomavirus in head and neck cancers. | 2017 | 26557412 | |
| a rare case of plantar epithelioma cuniculatum arising from a wart. | a 68-year-old man, a known case of hypertension, coronary artery disease and old cardiovascular accident with right-sided hemiplegia, came with the chief complaints of a large cauliflower like growth with pus discharge on the left heel since 15 years. the patient had sustained a penetrating injury by a thorn on the left heel region few days before the lesion appeared. dermatological examination revealed a single verrucous lesion measuring 7 × 7 cm on the left heel region associated with discharg ... | 2017 | 26538697 |
| [prevalence of non-vaccinable high risk genotypes of human papillomavirus in the early detection of cervical cancer program in cantabria]. | to estimate the prevalence of infection with non-vaccinable high risk genotypes of human papillomavirus (hpv). | 2017 | 26522783 |
| the influence of religiosity and spirituality on rural parents' health decision making and human papillomavirus vaccine choices. | general health implications of religiosity and spirituality on health have been associated with health promotion, so the purpose of this study was to examine the influence of religiosity and spirituality on rural parents' decision making to vaccinate their children against human papillomavirus (hpv). the associations of religiosity and spirituality with parental hpv vaccine decisions were examined in a sample of parents residing in small rural communities (n = 37). parents of children aged 9 to ... | 2017 | 26517344 |
| [history of the development of screening tests for cervical cancer]. | cervical cancer (cc) is one of the best known malignancies. currently, it is accepted that the etiological factor is persistent infection with high-risk human papillomavirus (hpv). even before the identification of its etiological factors, methods such as pap cytology and colposcopy were developed as tools for early diagnosis on cc and its precursor lesions. at the time when such tests were being developed, they were not fully accepted by the scientific community of the time; however, as time we ... | 2017 | 26506482 |
| early glottic squamous cell carcinoma in a 16-year-old: case report, review of the literature and pediatric head and neck radiotherapy guidelines. | squamous cell carcinoma in children and adolescents is extremely rare. less than 80 case reports have been reported in the literature since it was first reported in 1868. in this article, we intend to report a case where a 16-year-old girl who presented with complaints of change in voice was found to have early-stage vocal cord carcinoma on evaluation. | 2017 | 26464572 |
| adolescent premature ovarian insufficiency following human papillomavirus vaccination: a case series seen in general practice. | three young women who developed premature ovarian insufficiency following quadrivalent human papillomavirus (hpv) vaccination presented to a general practitioner in rural new south wales, australia. the unrelated girls were aged 16, 16, and 18 years at diagnosis. each had received hpv vaccinations prior to the onset of ovarian decline. vaccinations had been administered in different regions of the state of new south wales and the 3 girls lived in different towns in that state. each had been pres ... | 2017 | 26425627 |
| exponentially increasing incidences of cutaneous malignant melanoma in europe correlate with low personal annual uv doses and suggests 2 major risk factors. | for several decades the incidence of cutaneous malignant melanoma (cmm) steadily increased in fair-skinned, indoor-working people around the world. scientists think poor tanning ability resulting in sunburns initiate cmm, but they do not understand why the incidence continues to increase despite the increased use of sunscreens and formulations offering more protection. this paradox, along with lower incidences of cmm in outdoor workers, although they have significantly higher annual uv doses tha ... | 2017 | 26413188 |
| hr-hpv testing in the management of women with asc-us+ and in the follow-up of women with cytological abnormalities and negative colposcopy. recommendations of the italian group for cervical cancer screening (gisci). | compared to spontaneous screening, an organized screening programme is characterized by the presence of protocols and recommendations for all stages including follow-up. despite the availability of well-functioning screening programmes throughout the country, the follow-up protocol after an abnormal pap test and negative colposcopy is not clearly defined in italy, and there is no uniformity of indications. hpv testing for oncogenic human papillomavirus (hr-hpv) has a high negative predictive val ... | 2017 | 26405780 |
| two cases of cutaneous squamous cell carcinoma arising in immunosuppressed patients with chronic human papillomavirus infection. | increasing evidence has suggested that human papillomaviruses (hpvs) are linked to a large subset of numerous malignant tumors, including mucosal squamous cell carcinoma (scc); however, its involvement in cutaneous scc has not fully been elucidated. cutaneous scc is the second most common type of skin cancer and is increasing in frequency every year. since we have no satisfactory treatment for advanced scc, it is important to provide a definitive diagnosis and appropriate therapeutic interventio ... | 2017 | 26351427 |
| primary care physicians' adherence to guidelines and their likelihood to prescribe the human papillomavirus vaccine for 11- and 12-year-old girls. | inadequate physician adherence to guidelines has received scant attention as a possible cause of suboptimal human papillomavirus (hpv) vaccination rates. we assessed the extent to which primary care physicians (pcps) adhere to clinical guidelines and their reported intentions to prescribe hpv vaccine to females in the targeted age group, and how this is influenced by perceptions of guideline clarity and other factors. | 2017 | 26344447 |
| human papillomavirus knowledge and attitude among homeless women of new york city shelters. | human papillomavirus (hpv) has not been studied among homeless women in the united states. we assessed knowledge and attitudes regarding hpv infection and the hpv vaccine among homeless women. | 2017 | 26329258 |
| validation of the vaccination confidence scale: a brief measure to identify parents at risk for refusing adolescent vaccines. | to validate a brief measure of vaccination confidence using a large, nationally representative sample of parents. | 2017 | 26300368 |
| impact of gender-specific human papillomavirus vaccine recommendations on uptake of other adolescent vaccines: analysis of the nis-teen (2008-2012). | in the united states, human papillomavirus vaccination was routinely recommended for adolescent females in 2006 and provisionally recommended for adolescent males in 2009. we evaluated the hypothesis that gender-specific human papillomavirus vaccination recommendations would impact gender-specific uptake of other vaccines using national immunization survey-teen public use data sets (2008-2012). female adolescents had higher coverage than males of at least 1 other adolescent vaccine in 2008 (3.0% ... | 2017 | 26280380 |
| human papillomavirus deoxyribonucleic acid in non-genital benign papillomatous skin lesion. | 2017 | 26288460 | |
| no evidence of human papilloma virus infection in basal cell carcinoma. | basal cell carcinoma (bcc) is the most common skin cancer among whites, and several risk factors have been discussed in itsdevelopment and progress. detection of human papilloma virus (hpv) deoxyribonucleic acid (dna) bccs in some studies suggests that the virus may play a role in the pathogenesis of this disease. several molecular studies showed conflicting reports. | 2017 | 26288402 |
| hpv9 vaccine for the prevention of human papillomavirus-related cancers. | human papillomavirus (hpv) is the most common sexually transmitted infection (sti) in the united states, with approximately 79 million americans currently infected. persistent infection with hpv has been identified as the causative factor in the development of invasive cervical cancer as well as other oral and genital cancers in women and men. the quadravalent hpv4 vaccine has been available since 2006. in december 2014, the u.s. food and drug administration (fda) approved the hpv9 vaccine that ... | 2017 | 26264802 |
| reprogrammed crispr-cas9 targeting the conserved regions of hpv6/11 e7 genes inhibits proliferation and induces apoptosis in e7-transformed keratinocytes. | the persistence infection of low-risk type (type 6 or type 11) of human papillomavirus (hpv) is the main cause of genital warts. given the high rate of recurrence after treatment, the use of a new molecular agent is certain to be of value. the aim of this study was to achieve targeted inactivation of viral e 7 gene in keratinocytes using the reprogrammed clustered regularly interspaced short palindromic repeats (crispr)/crispr-associated (cas) 9 system. to accomplish this, a universal crispr-cas ... | 2017 | 26228041 |
| communication practices about hpv testing among providers in federally qualified health centers. | little is known about the information providers share with patients when ordering a co-test, or combined human papillomavirus (hpv) and papanicolaou (pap) test, for cervical cancer screening. we assessed provider perceptions of such communication practices with female patients aged 30-60 years. | 2017 | 26213683 |
| provider beliefs associated with cervical cancer screening interval recommendations: a pilot study in federally qualified health centers. | among providers who serve low-income and uninsured women, resistance to extending the cervical cancer screening interval following normal pap and co-test results has been documented. our objective was to examine provider characteristics and beliefs associated with guideline-consistent screening interval recommendations. | 2017 | 26203428 |
| catching up with the hpv vaccine: challenges and opportunities in primary care. | data confirm that high rates of human papillomavirus (hpv) vaccination have not been achieved despite strong clinician endorsement of the vaccine. we conducted a study of primary care clinicians to assess the broad range of health care delivery, health policy, and attitudinal factors influencing vaccination uptake and opportunities for informed decision making. | 2017 | 26195681 |
| a cost analysis of the 1-2-3 pap intervention. | cervical cancer places a substantial economic burden on our healthcare system. the three-dose human papillomavirus (hpv) vaccine series is a cost-effective intervention to prevent hpv infection and resultant cervical cancer. despite its efficacy, completion rates are low in young women aged 18 through 26 years. 1-2-3 pap is a video intervention tested and proven to increase hpv vaccination completion rates. | 2017 | 26167424 |
| hypersensitivity to chemoradiation in fanca carrier with cervical carcinoma-a case report and review of the literature. | compared to fanconi anemia (fa) patients with homozygous defective two-alleles inheritance, there is a scarce or no evidence on one defective allele fanca carriers, with respect to their cancer incidence, clinical and in vitro radiosensitivity and chemosensitivity. on that account, we report a case of a 30-year old fanca mutation carrier woman with uterine cervix adenocarcinoma who was treated with chemoradiotherapy, in which unexpected acute toxicity and fatal late morbidity occured. | 2017 | 26109920 |
| role of human papillomavirus in oral squamous cell carcinoma and oral potentially malignant disorders: a review of the literature. | human papillomaviruses (hpvs) are epitheliotropic viruses with an affinity for keratinocytes and are principally found in the anogenital tract, urethra, skin, larynx, tracheobronchial and oral mucosa. on the basis of high, but variable frequency of hpv in oral squamous cell carcinoma (oscc), malignant potential of hpv infection has been hypothesized but not definitely confirmed. the aim of this review was to highlight the genomic structure and possible mechanism of infection and carcinogenesis b ... | 2017 | 26097339 |
| human papillomavirus vaccination among adults and children in 5 us states. | the centers for disease control and prevention advisory committee for immunization practices has recommended human papillomavirus (hpv) vaccines for use in children and young adults for preventing hpv-related diseases, but hpv vaccine coverage is low in the united states. | 2017 | 26035648 |
| prevalence of human papillomavirus in oropharyngeal cancer: a systematic review. | the global incidence of oropharyngeal squamous cell carcinoma (opscc) has been increasing, and it has been proposed that a rising rate of human papillomavirus (hpv)-associated cancers is driving the observed changes in opscc incidence. we carried out this systematic review to further examine the prevalence of hpv in opscc over time worldwide. | 2017 | 26049691 |
| autoimmune/auto-inflammatory syndrome induced by adjuvants (asia) after quadrivalent human papillomavirus vaccination in colombians: a call for personalised medicine. | this was a case study in which 3 patients with autoimmune/auto-inflammatory syndrome induced by adjuvants (asia) after quadrivalent human papillomavirus vaccination (hpv) were evaluated and described. all the patients were women. diagnosis consisted of hla-b27 enthesitis related arthritis, rheumatoid arthritis and systemic lupus erythematous, respectively. our results highlight the risk of developing asia after hpv vaccination and may serve to increase the awareness of such a complication. facto ... | 2017 | 25962455 |
| impact of an electronic health record (ehr) reminder on human papillomavirus (hpv) vaccine initiation and timely completion. | the initiation and timely completion of the human papillomavirus (hpv) vaccine in young women is critical. we compared the initiation and completion of the hpv vaccine among women in 2 community-based networks with electronic health records: 1 with a prompt and reminder system (prompted cohort) and 1 without (unprompted cohort). | 2017 | 25957365 |
| successful implementation and results of an hpv vaccination program in geneva canton, switzerland. | we describe a human papillomavirus (hpv) vaccination program implemented since 2007 in geneva canton, switzerland, that used school services, a public hospital, and private physicians as vaccination providers. we assessed program performance with the evolution of immunization coverage during the first four years of program implementation. we measured vaccination coverage of the target population using individual records of vaccination status collected by service providers and transmitted to the ... | 2017 | 25931623 |
| microparticles mediate human papillomavirus type 6 or 11 infection of human macrophages. | 2017 | 25891215 | |
| profile and retrospective analysis of the use of preventive strategies in patients with cervical cancer in south-south nigeria. | cervical cancer is the commonest malignancy of the female genital tract in developing countries, with a global burden of 530,000 new cases annually. this study aims to review the current situation of this important malignancy and to assess the previous use of preventive measures in patients with cervical cancer at the port harcourt teaching hospital (upth), port harcourt, nigeria. | 2017 | 25838625 |
| bronchial fibroepithelial polyp: a clinico-radiologic, bronchoscopic, histopathological and in-situ hybridisation study of 15 cases of a poorly recognised lesion. | bronchial fibroepithelial polyp is an uncommon, poorly recognised lesion, lacking clear diagnostic criteria at histology, but possibly mimicking neoplastic growth on clinico-radiologic and histopathological grounds. the aim of this study was to define the clinico-pathological features, bronchoscopic appearance and treatment of bronchial fibroepithelial polyp. | 2017 | 25832329 |
| hpv and oral lesions: preventive possibilities, vaccines and early diagnosis of malignant lesions. | the importance of hpv in world healthy is high, in fact high-risk hpv types contribute significantly to viral associated neoplasms. in this article we will analyze vary expression of hpv in oral cavity both benign and malignant, their prevalence and the importance in early diagnosis and prevention. the classical oral lesions associated with human papillomavirus are squamous cell papilloma, condyloma acuminatum, verruca vulgaris and focal epithelial hyperplasia. overall, hpv types 2, 4, 6, 11, 13 ... | 2017 | 27555904 |
| further stimulation of cellular immune responses through association of hpv-16 e6, e7 and l1 genes in order to produce more effective therapeutic dna vaccines in cervical cancer model. | cervical cancer has been shown to be highly associated with human papillomavirus (hpv) infection. the viral oncogenes e6 and e7 are constantly expressed by the tumor cells and are therefore potent targets for therapeutic genetic vaccination. in the present study, it was investigated the potential effect of hpv-16 e6, e7 and l1 co-administration to activate specific cytotoxic t lymphocytes in tumor mice models. | 2017 | 25821567 |
| multiple synchronous verrucous carcinomas of the scalp in the background of generalized verruca vulgaris. | verrucous carcinoma (vc) is a clinicopathologic entity which is defined as a locally aggressive, clinically exophytic, slow-growing, well-differentiated, squamous cell carcinoma with negligible metastatic potential. the cutaneous form of vc is typically known to arise from the palmoplantar and the genitocrural areas. involvement of the scalp is extremely rare. multiple synchronous involvement of the scalp by vc along with associated generalized verruca vulgaris has possibly never been reported b ... | 2017 | 25814709 |
| motivation for hpv vaccination among young adult men: validation of ttm decisional balance and self-efficacy constructs. | in the united states, 36% of human papillomavirus (hpv)-related cancers occur among men. hpv vaccination can substantially reduce the risk of hpv infection; however, the vast majority of men are unvaccinated. this study developed and validated transtheoretical model-based measures for hpv vaccination in young adult men. | 2017 | 25806567 |
| knowledge, perceptions, and decision making about human papillomavirus vaccination among korean american women: a focus group study. | as one of the fastest growing ethnic minority groups in the united states, korean american (ka) women experience a heightened cervical cancer burden. the advent of the human papillomavirus (hpv) vaccine offers an unprecedented opportunity to eliminate cervical cancer disparities in ka women. however, the uptake of hpv vaccine among ka adolescents remains suboptimal. hence, we set out to explore knowledge, perceptions, and decision making about hpv vaccination among ka women. | 2017 | 25747518 |
| evaluation of the impact of human papillomavirus dna self-sampling on the uptake of cervical cancer screening. | the rate of uptake of the papanicolaou (pap) smear is generally low. its causal relationship with human papillomavirus (hpv) dna allows hpv dna self-sampling to be used as an alternative screening tool for cervical cancer. | 2017 | 25730587 |
| a human papillomavirus type 16 e6 52-62 cd4 t-cell epitope restricted by the hla-dr11 molecule described in an epitope hotspot. | cell-mediated immune responses to the human papillomavirus type 16 (hpv 16) e6 protein have been shown to be important in viral clearance and in regression of cervical lesions. here, detailed analyses of a novel hpv 16 e6 cd4 t-cell epitope from a subject with cervical intraepithelial neoplasia 1 are described. this subject had demonstrated hpv 16 cd4 t-cell responses to multiple regions within the e6 protein. isolation and cloning of cd4 t-cells were performed by magnetic selection of interfero ... | 2017 | 25685851 |
| comparing the results of pap smear and direct visual inspection (dvi) with 5% acetic acid in cervical cancer screening. | cervical cancer is the most second common cancer among iranian women. this study was carried out to compare the results of pap smear method and direct visual inspection (dvi) with 5% acetic acid in cervical cancer screening in tabriz, iran. | 2017 | 25657491 |
| knowledge and perception of human papilloma virus vaccine among the antenatal women in a nigerian tertiary hospital. | cervical cancer is a major health problem globally, especially in sub-saharan africa, nigeria inclusive. one of the preventive measures is the vaccination of teenagers against oncogenic human papilloma virus. the aim of this study was to find out the level of knowledge mothers possess about these vaccines and their willingness to administer vaccination to their teenage girls. | 2017 | 25657489 |
| cost analysis of different cervical cancer screening strategies in mexico. | to compare the costs and number of undetected cases of four cervical cancer screening strategies (ccss) in mexico. | 2017 | 25604287 |
| design and efficacy of a multilingual, multicultural hpv vaccine education intervention. | the human papillomavirus (hpv) is the precursor and the single, most important risk factor for cervical cancer. it is also the most commonly sexually transmitted infection in the united states. an estimated 20 million persons are currently infected with the virus, with an estimated 6 million new infections occurring annually and 12,000 new cervical cancer cases and 4,000 cervical cancer deaths annually. the human papillomavirus (hpv) vaccine is thus an especially important preventive measure for ... | 2017 | 27540413 |
| the digital distribution of public health news surrounding the human papillomavirus vaccination: a longitudinal infodemiology study. | new media changes the dissemination of public health information and misinformation. during a guest appearance on the today show, us representative michele bachmann claimed that human papillomavirus (hpv) vaccines could cause "mental retardation". | 2017 | 27227125 |
| targeted therapy in oropharyngeal squamous cell carcinoma: the implications of hpv for therapy. | oropharyngeal cancers caused by human papillomaviruses (hpv) have a different epidemiology, prognosis, genetic mutational landscape, response to treatment, and outcome when compared to hpv-negative cancers. in this review, a summary of our current understanding of hpv in head and neck cancer and the important advances that have shown hpv to be an etiological agent are discussed. hpv-positive and hpv-negative tumors are compared discussing clinicopathological factors, prognosis, outcome following ... | 2017 | 27182480 |
| porokeratoma: a possible association with human papillomavirus infection. | porokeratoma is a rare, relatively newly described and still unclear entity. here, we describe the case of a 52-year-old male patient who presented with four well-defined, verrucous and hyperkeratotic lesions. microscopically, one of the lesions showed acanthopapillomatosis overlying compact orthokeratosis. prominent broad and confluent cornoid lamellae were present, with no granular layer and some dyskeratotic keratinocytes. pcr sequencing and in situ hybridization revealed the presence of huma ... | 2017 | 27047933 |
| the human papillomavirus vaccination: a review of the cost-effectiveness studies. | the human papillomavirus (hpv) is one of the most common sexually transmitted viruses, its infection with certain subtypes is the primary cause of cervical cancer. several countries conducted specific cost-effectiveness evaluations toward hpv vaccination. the constant growth of healthcare demand, in an economic context characterized by limited resources, requires that the decision-making process be based on the comparison of alternative choices. this study offers an overview of the published cos ... | 2017 | 25524200 |
| predictors of having heard about human papillomavirus vaccination: critical aspects for cervical cancer prevention among colombian women. | to determine whether the probability of having heard about human papillomavirus (hpv) vaccination differs by socio-demographic characteristics among colombian women; and whether the effect of predictors of having heard about hpv vaccination varies by educational levels and rural/urban area of residence. | 2017 | 25444387 |
| validation of an hpv16-mediated carcinogenesis mouse model. | human papillomavirus type 16 (hpv16) infection is a necessary but alone insufficient cause of invasive cervical cancer (icc) and likely causes other genital cancers. individual genetic variability influences the natural history of the neoplasm. developing a variety of animal models to investigate hpv16-mediated carcinogenesis is important to phase 1 trials for human cancer treatments. | 2017 | 25189887 |
| screening of human papillomavirus infection in women with systemic sclerosis. | high risk human papilloma-viruses (hr hpv) are associated with risk of cervical dysplasia and carcinoma. the risk is increased in patients with immune deficiency or auto-immune disease as systemic lupus erythematosus. currently, no data are available about the human papillomavirus status in women with systemic sclerosis (ssc). | 2017 | 25151849 |
| adolescent onset of localized papillomatosis, lymphedema, and multiple beta-papillomavirus infection: epidermal nevus, segmental lymphedema praecox, or verrucosis? a case report and case series of epidermal nevi. | herein, we report the case of a 12-year-old female who noted the recent onset of an oval, circumscribed, 10-cm papillomatous plaque affecting the thigh and vulva that showed histologic signs of lymphedema without evidence of secondary lymphedema. the sequencing of genes associated with a delayed onset of lymphedema or epidermal nevi (en) - gata2 and gjc2, and hras and kras, respectively - showed wild-type alleles. polymerase chain reaction for human papillomavirus (hpv) dna demonstrated infectio ... | 2017 | 27047923 |
| predictive value of epigenetic alterations in head and neck squamous cell carcinoma. | head and neck cancer collectively describes malignant tumors originating from the mucosal surface of the upper aerodigestive tract. these tumors pose a great threat to public health because of their high incidence and mortality. traditional risk factors are tobacco and alcohol abuse. more recently, infection by high-risk types of human papilloma virus (hpv) has been identified as an additional risk factor, especially for oropharyngeal squamous cell carcinoma (opscc). moreover, hpv-positive opscc ... | 2017 | 27308324 |
| human papillomavirus detection in cervical scrapes from women attended in the family health program. | to survey the prevalence of human papillomavirus, associated risk factors and genotype distribution in women who were referred to cervical cancer screening when attended in a family health program. | 2017 | 24553709 |
| postural orthostatic tachycardia with chronic fatigue after hpv vaccination as part of the "autoimmune/auto-inflammatory syndrome induced by adjuvants": case report and literature review. | we report the case of a 14-year-old girl who developed postural orthostatic tachycardia syndrome (pots) with chronic fatigue 2 months following gardasil vaccination. the patient suffered from persistent headaches, dizziness, recurrent syncope, poor motor coordination, weakness, fatigue, myalgias, numbness, tachycardia, dyspnea, visual disturbances, phonophobia, cognitive impairment, insomnia, gastrointestinal disturbances, and a weight loss of 20 pounds. the psychiatric evaluation ruled out the ... | 2017 | 26425598 |
| metronomic cyclophosphamide enhances hpv16e7 peptide vaccine induced antigen-specific and cytotoxic t-cell mediated antitumor immune response. | in clinical trials, metronomic cyclophosphamide (cpa) is increasingly being combined with vaccines to reduce tumor-induced immune suppression. previous strategies to modulate the immune system during vaccination have involved continuous administration of low dose chemotherapy, studies that have posed unique considerations for clinical trial design. here, we evaluated metronomic cpa in combination with a peptide vaccine targeting hpv16e7 in an hpv16-induced tumor model, focusing on the cytotoxic ... | 2017 | 25960932 |
| second european multi-disciplinary conference of national strategies for chlamydia trach. and human papillomavirus nscp conf. in berlin, 2013 enhanced detection, management and surveillance of sexually transmitted infections in europe are essential! | there is a need for updated guidance on detection, management and surveillance of sexually transmitted infections (stis). chlamydia, gonorrhoea and syphilisreporting needs to be mandatory in more european countries to aid collection of data. more widespread chlamydia screening is needed in many countries as this is the only way to reduce complications. the role of human papillomavirus (hpv) screening in a situation where the prevalence of hpv infection has dropped significantly was also discusse ... | 2017 | 24355218 |
| surgical treatment and adjuvant therapies of recurrent respiratory papillomatosis. | recurrent respiratory papillomatosis or recurrent laryngeal papillomatosis is a disease of the larynx caused by human papilloma virus, characterized by verrucous epithelial lesions and usually recurring. in the literature there are several types of treatment, such as surgery to cold, laser and/or use of microdebrider, as of adjuvant therapies; all possible to decrease the permanent sequelae of the disease. | 2017 | 24141682 |
| p16ink4a immunohistochemistry for detection of human papilloma virus-associated penile squamous cell carcinoma is superior to in-situ hybridization. | we evaluated p16ink4a as a reliable option to detect human papilloma virus (hpv) dna in penile tumor specimens. formalin-fixed paraffin embedded samples of 26 patients with penile cancer and another 18 cases with non-tumorigenic lesions were stained by three different widely used commercially available chromogenic in-situ hybridization assays high-risk hpv cish y1443 (genpoint, dako), pan hpv cish y1404 (genpoint, dako), inform hpv iii (ventana, tucson, arizona) and p16ink4a immunohistochemistry ... | 2017 | 24067458 |
| human papillomavirus types in cases of squamous cell carcinoma of head and neck in colombia. | estimating the type-specific prevalence of human papillomavirus (hpv) in head and neck cancer (hnscc) is helpful in predicting the impact of hpv immunization. | 2017 | 23743755 |
| the role of family history of cancer on cervical cancer screening behavior in a population-based survey of women in the southeastern united states. | our objective was to determine the association of self-reported family history of cancer (fhc) on cervical cancer screening to inform a potential link with cancer preventive behaviors in a region with persistent cancer disparities. | 2017 | 23722075 |
| intralesional cidofovir in the treatment of cutaneous warts in a renal transplant patient. | cutaneous warts are often recalcitrant to conventional therapy in immunocompromised patients. cidofovir is a potent antiviral agent shown to have a broad spectrum of action against dna virus, including human papillomavirus. | 2017 | 23149209 |
| production of biopharmaceutical proteins by yeast: advances through metabolic engineering. | production of recombinant proteins for use as pharmaceuticals, so-called biopharmaceuticals, is a multi-billion dollar industry. many different cell factories are used for the production of biopharmaceuticals, but the yeast saccharomyces cerevisiae is an important cell factory as it is used for production of several large volume products. insulin and insulin analogs are by far the dominating biopharmaceuticals produced by yeast, and this will increase as the global insulin market is expected to ... | 2017 | 23147168 |
| imagined anatomy and other lessons from learner verification interviews with mexican immigrant women. | to identify clearer, learner-preferred, educational approaches for aspects of cervical cancer education found to be difficult to understand for low-literacy, mexican, immigrant women. | 2017 | 23030624 |
| epidemiological study of hpv in oral mucosa through pcr. | the human papillomavirus (hpv) belongs to the papillomaviridae family and has a capsid and a single dna strand. its infection occurs mainly through sexual intercourse, having an important tropism for skin and mucosal cells. | 2017 | 22936139 |
| laboratory and clinical aspects of human papillomavirus testing. | human papillomavirus (hpv) infection is associated with a wide spectrum of disease that ranges from self-limited skin warts to life-threatening cancers. since hpv plays a necessary etiological role in cervical cancer, it is logical to use hpv as a marker for early detection of cervical cancer and precancer. recent advances in technology enable the development of high-throughput hpv assays of different formats, including dna-based, mrna-based, high-risk group-specific and type-specific methods. t ... | 2017 | 22913405 |
| the females against cancer educational series: a qualitative evaluation of mother/daughter knowledge and perceptions of human papillomavirus and its related cancers. | to evaluate the knowledge, perceptions, and effectiveness of an human papillomavirus (hpv)/cervical cancer education/prevention program. | 2017 | 22774387 |
| eyelid verrucous carcinoma. | to report a case of verrucous carcinoma (vc) that presented as an eyelid mass on the right eye. | 2017 | 28252698 |
| extensive mucocutaneous verruca vulgaris in a nonimmunocompromised patient. | papilloma virus infections of the oral cavity have been long recognized with various clinical expressions characterized as verruca vulgaris, heck's disease, multiple papilloma and condyloma acuminata. in this paper, we are highlighting a case of verruca vulgaris involving the oral cavity with extensive skin lesions in a nonimmunocompromised 9-year-old boy. different treatment modalities are discussed in this article. | 2017 | 27616862 |
| premalignant epithelial changes in the uterine cervix of women aged less than thirty with special emphasis on the coexistent condylomatous lesions. | one hundred and sixty two women aged less than 30 years with either a dysplastic change or carcinoma in situ of the squamous epithelium of the uterine cervix were histologically assessed with special emphasis on the detection of the recently described condylomatous lesions (the flat, inverted and the papillomatous ones) caused by human papilloma virus (phv). a total of 134 condylomatous (co) lesions were -- discovered, the flat type being the most frequent one (75.4%) followed in decreasing orde ... | 2017 | 28211420 |
| 3,3'-diindolylmethane increases serum interferon-γ levels in the k14-hpv16 transgenic mouse model for cervical cancer. | while cervical cancer incidence and mortality rates have declined in the united states, this cancer represents a worldwide threat. human papilloma viral infection causes cervical neoplasia (cin). 3,3'-diindolylmethane (dim) prevents or inhibits the progression from cervical dysplasia to cancer. the aim of this study is to determine the most effective dose of dim given continuously in food, that significantly increases serum interferon gamma levels (ifn-γ) in the k14-hpv16 transgenic mouse model ... | 2016 | 22351660 |
| clinical decision support with automated text processing for cervical cancer screening. | to develop a computerized clinical decision support system (cdss) for cervical cancer screening that can interpret free-text papanicolaou (pap) reports. | 2016 | 22542812 |
| the impact of policy and screening on cervical cancer in england. | there has been a significant statistical decrease in the incidence of cervical cancer since screening programmes have been introduced. this article will explore and evaluate the impact of the cancer reform strategy on cervical screening in england, which preceded the government's policy for cancer care announced in january 2011. the strategy raised the initial age of screening from 20 to 25 years of age. this left a group of the population who could not access screening while also not being elig ... | 2016 | 22470899 |
| american cancer society, american society for colposcopy and cervical pathology, and american society for clinical pathology screening guidelines for the prevention and early detection of cervical cancer. | an update to the american cancer society (acs) guideline regarding screening for the early detection of cervical precancerous lesions and cancer is presented. the guidelines are based on a systematic evidence review, contributions from 6 working groups, and a recent symposium cosponsored by the acs, the american society for colposcopy and cervical pathology, and the american society for clinical pathology, which was attended by 25 organizations. the new screening recommendations address age-appr ... | 2016 | 22422631 |
| sexually transmitted infections: what's new? | since the beginning of the third millennium the incidence of sexually transmitted infections (stis) is rising in europe and in belgium, and this after a steady decline in the second half of last century. it concerns new or lesser known diseases such as hepatitis c and lymphogranuloma venereum (lgv) and 'old' diseases such as gonorrhoea and syphilis, occurring in specific risk groups. in this article we give an update of the diagnostic means and therapeutic challenges that are of interest for the ... | 2016 | 22897062 |
| acquired epidermodysplasia verruciformis in a child with atopic dermatitis. | a 4-year-old girl with an established diagnosis of atopic dermatitis, previously severe and treated with cyclosporine, developed widespread papules that demonstrated changes consistent with epidermodysplasia verruciformis on biopsy. human papilloma virus (hpv) typing was performed and was consistent with epidermodysplasia verruciformis-type hpv (type 5). these lesions rapidly resolved with a 2-week course of imiquimod. rapid resolution and no family history of epidermodysplasia verruciformis mak ... | 2016 | 22938530 |
| de-intensification of treatment for human papilloma virus associated oropharyngeal squamous cell carcinoma: a discussion of current approaches. | 2016 | 24674166 | |
| cervical cancer screening in the era of human papillomavirus testing and vaccination. | cervical cancer screening algorithms have changed with the introduction of testing for human papillomavirus (hpv) and better understanding of the natural history of hpv. this review was undertaken to present recent developments related to cervical cancer screening, with hpv testing as a focus. specifically, guidelines now recommend initiating cervical cancer screening at age 21, stopping at age 65 to 70 if previous tests are normal, and screening no more than every 2 to 3 years. human papillomav ... | 2016 | 23050698 |
| [anal intraepithelial neoplasia]. | anal intraepithelial lesions are caused by chronic infection with oncogenic types of human papillomavirus. their incidence and prevalence are increasing, especially among patients with hiv infection. their natural history is not well known, but high-grade intraepithelial lesions seem to have an important risk to progress to squamous cell carcinoma. their treatment can be achieved by many ways (surgery, coagulation, imiquimod, etc.) but there is a high rate of recurrent lesions. pretherapeutic ev ... | 2016 | 23122632 |
| acceptability and usability of self-collected sampling for hpv testing among african-american women living in the mississippi delta. | human papillomavirus (hpv) dna testing has been shown to be an effective approach to cervical cancer screening, and self-collection sampling for hpv testing could be a potential alternative to pap test, provided that women who tested positive by any method get timely follow-up and care. this feasibility study examined acceptability and usability of self-collected sampling for hpv testing among african-american (aa) women in the mississippi delta to inform the development of interventions to prom ... | 2016 | 23410619 |
| human papillomavirus vaccine coverage among females aged 11 to 17 in texas counties: an application of multilevel, small area estimation. | local data are often used to plan and evaluate public health interventions and policy. with increasingly fewer public resources to collect sufficient data to support direct estimation of local outcomes, methods for deriving small area estimates are vital. the purpose of this study is to describe the county-level geographic distribution of human papillomavirus (hpv) vaccine coverage among adolescent females in texas using multilevel small area estimation. | 2016 | 23481692 |