Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| [vaccination against hepatitis b in man]. | the preparation of a vaccine against hepatitis b is described. the vaccine is prepared from the hb viral coat (hbs ag) purified and formalin inactivated. the hbs ag is isolated and purified from the blood of healthy hbs ag positive donors by means of an immunoadsorbent technique. the inocuity and efficacy were tested on chimpanzees. vaccination was then applied in an attempt to protect patients and ward staff in a high risk haemodialysis unit. the efficacy of the vaccine was assessed by humoral ... | 1977 | 401985 |
| [infant death caused by neonatal hepatitis b virus infection]. | 1977 | 846600 | |
| [prevention of neontal hepatitis b]. | 1977 | 846603 | |
| hepatitis, type b in haemophiliacs. relation to the source of clotting factor concentrates. | 36 children aged 3 to 18 years receiving substitution therapy for haemophilia during the period 1970 to 1976 were studied for infection with hepatitis b virus by assays for hbsag, anti-hbs, and anti-hbc. clinical hepatitis b occurred in 3 patients (8%) and serological evidence of infection was found in further 13 (36%). the occurrence of infection was associated with age but less so with the total amount of transfusion. estimates of the risk of infection by clotting factor material of different ... | 1977 | 847395 |
| difference in the distribution of e antigen among different ethnic groups in a population of blood donors. | sensitive techniques were used to detect e antigen and the corresponding antibody (anti-e) among 368 voluntary blood donors positive for hepatitis b surface antigen in the montreal area and 310 people living in close contact with them. neither e nor anti-e was found in the absence of markers of hepatitis b virus (hbv). among the blood donors e antigen was detected in 23 and anti-e in 313, and 32 were negative for both markers. of the 368 blood donors 330 were of french origin and 38 from other e ... | 1977 | 849558 |
| vaccines against hepatitis b. | 1977 | 850491 | |
| some sex- and age-dependent correlations in acute viral hepatitis. | hbsag was found to be present in 28.7% of 1980 sera from acute viral hepatitis (avh) patients tested by immunodiffusion and counterimmunoelectrophoresis. the incidence of hbsag-positive avh cases was lower in female subjects aged 10-19 years. the follow up of sgpt, bilirubinemia and thymol turbidity kinetics in 473 of the patients revealed some hbsag-dependent differences. such differences oscillated more markedly in adults than in children and were less obvious in women. the possible involvemen ... | 1977 | 850999 |
| treatment of chronic hepatitis b virus infection with rebavrin. | 1977 | 851777 | |
| the lack of nurse-infant transmission of type b hepatitis in a special care nursery. | twenty-four infants cared for by a nurse who developed acute b hepatitis with hbsag present in her serum and saliva were examined for serologic evidence of hepatitis b virus transmission. none of the infants had hbsag by radioimmunoassay or anti-hbc by complement fixation. one infant had anti-hbs whose transient presence was consistent with passive acquisition. using sensitive serologic tests, no identifiable risk to newborn infants in a special care nursery could be documented as a result of ex ... | 1977 | 874648 |
| [occurrence of nuclear bodies in acute viral hepatitis]. | needle-hepatic-biopsy of 10 patients with acute viral hepatitis was investigated by the aid of electron microscope. in the hepatocytes striking nucleolar alterations were observed, i.e. breakage and dispersion of the nucleolonema in the karyoplasma. not infrequently nuclear bodies were seen. according to the present knowledge it can not be decided whether nuclear bodies are normal constituents of the hepatocytes or product of the impaired function. complex nuclear bodies--in acute viral hepatiti ... | 1977 | 854038 |
| [immune mechanisms in hepatitis b. new aspects and consequent practices]. | the different types of immune responses occurring during hepatitis b virus infection are reviewed. the responses specific for hbsag (hepatitis b surface antigen) are important in the pathogenesis of chronic liver disease. the cell-mediated immunity specific for this antigen seems to be responsible for cytolysis occurring when the antigen is located within the hepatocyte (acute and persistent hepatitis). it is also responsible for the subsequent elimination of the virus. immune complexes in antib ... | 1977 | 854720 |
| [hepatitis b: new aspects, practical implications. virology and epidemiology]. | although neither a nor b hepatitis virus (hav, hbv) has been grown in cell or organ cultures, both agents have been identified and characterized. the subsequent ability to diagnose hepatitis a and b has led to the recognition of a third form of viral hepatitis, "non a--non b hepatitis". it has been possible to eliminate hbv from blood used for transfusion and from blood products, and the combined results of hepatitis research have led to a better understanding of the epidemiology and pathogenesi ... | 1977 | 857308 |
| high prevalence of e antigen among healthy blood donors carrying hepatitis b surface antigen in japan. | hepatitis b surface antigen (hbsag) was detected by an immune adherence haemagglutination method in the serum samples of 292 voluntary, apparently healthy blood donors at four regional blood centres in japan. their serum samples were concentrated 3-fold and tested for e antigen (e ag) and antibody to e (anti-e) by immunodiffusion. the e ag was found in 41 samples (14.0%) and anti-e in 57 (18.6%). when 100 randomly selected serum samples containing hbsag were tested as they were (unconcentrated), ... | 1977 | 857427 |
| [detection of superficial antigen of hepatitis b virus and further studies in voluntary donors in navarra]. | 1977 | 860063 | |
| [hbeag and anti-hbe in various groups of acute hepatitis patients and carriers of hbsag]. | serial samples of serum from 44 patients with acute hepatitis b were examined by immunodiffusion for hepatitis b e antigen (hbeag) and its antibody (anti-hbe). the antigen was detected in the serum of 5 (11.3%) of the patients and antibody in 12 (27.3%). two patterns of events emerged during the study: a) hb-eag was found only in the samples collected during the early acute phase of the illness but anti-hbe was not detectable at any time; b) hbeag was not found during the acute illness but anti- ... | 1977 | 861075 |
| hla in different forms of chronic active hepatitis. a comparison between adult patients and children. | 108 adult patients and 34 children with chronic active hepatitis (cah) are divided in four groups on the basis of presence and absence of hepatitis b surface antigen (hbsag) and autoantibodies (autoab). there are significant differences in the numeric distribution among the four groups and the sex distribution between adult patients and children, but no differences in the frequencies of the hla antigens tested. an increased frequency of hla-b8 (and hla-a1) compared with normal controls and the o ... | 1977 | 863130 |
| immunoglobulin therapy for patients exposed to hepatitis b virus. | 1977 | 864296 | |
| association between hepatitis b virus and essential mixed cryoglobulinemia. | in view of a high frequency of liver involvement in patients with essential mixed cryoglubulinemia, we looked for evidence for hepatitis b virus infection in 25 serum specimens and 19 cryoprecipitates obtained from 30 patients. three of the 25 serum specimens contained hbs ag, and 12 had antibody. the frequency of positive results was increased to six and 11 of 19 respectively when cryoprecipitates were examined, and 14 of 19 (74 per cent) of the cryoprecipitates were positive for either hbs ag ... | 1977 | 865530 |
| [inhibition of the migration of humanleukocytes by the surface antigen of the hepatitis b virus]. | 1977 | 867607 | |
| hepatitis b surface antigen and chronic hepatitis in infants born to asymptomatic carrier mothers. | twenty-three infants born to asymptomatic hepatitis b surface antigen (hbsag) carrier mothers were followed up to determine the vertical transmission of hepatitis b virus. four infants became positive for hbsag within four months after birth. three showed hepatic dysfunction; liver biopsy specimens demonstrated mild chronic hepatitis in one and persistent hepatitis in another. in six infants followed up for more than six months after birth, antibody to hbsag (anti-hbs) without antigenemia could ... | 1977 | 868815 |
| hepatitis b antigen and antibody in a male homosexual population. | sera from 600 male homosexual patients were tested for hepatitis b antigen (hbs ag) and its antibody (hbs ab). thirty-one men (5-2%) were positive for hbs ag. testing for hbs ab by immuno-osmoelectrophoresis 33 men (5-5%) were positive. however, sera of 85 patients negative for hbs ab by routine methods were examined for hbs ab by radioimmune assay. thirty (35%) sera were found to be positive. no absolute correlation between the detection of hbs ag, or previous history of hepatitis, jaundice, or ... | 1977 | 870144 |
| role of sexual and non-sexual practices in the transmission of hepatitis b. | medical, social, and sexual histories were taken from 198 men attending a department for sexually transmitted diseases. their blood was tested for hepatitis b surface antigen and its antibody, and also for syphilis and liver function. infection with hepatitis b virus was found to be common among practising homosexuals and to occur much more frequently in them than in heterosexuals. hepatitis b appeared to be transmitted sexually rather than by other means, but it was not possible in this study t ... | 1977 | 871896 |
| release of e antigen from a dane particle-rich preparation of hepatitis b virus. | tween 80 treatment of a dana particle-rich pellet obtained from sera of a carrier with a hepatitis type b infection resulted in the release of e antigen. | 1977 | 873617 |
| [hepatitis b virus components and cytoplasmic virus-like corpuscles in chronic hepatitis (electron microscopic study)]. | author in the needle-biopsy specimen of the liver of a hbsag positive patient previously treated with immunosupressive preparates (corticosteroid + imuran) in the nuclei of hepatocytes by the aid of electron microscope revealed ring-shaped particula of 20-25 nm in diameter (core), in the cytoplasma of ground-glass hepatocytes in the canals of the rough-surfaced endoplasmic reticulum filamentous formations in average of 23nm in diameter (surface antigen). in addition in a few number cytoplasmic c ... | 1977 | 876257 |
| viral hepatitis b: aspects of environmental control. | in recent years it has become increasingly evident that viral hepatitis type b is a major disease problem among patients and/or health professionals associated with environments such as hemodialysis centers, dental operatories, clinical laboratories, and institutions for the mentally retarded. studies have incriminated the intramural environment as well as specialized equipment and procedures as important factors in disease transmission. with hepatitis b surface antigen (hbsag) as a marker of po ... | 1977 | 914523 |
| hepatitis b virus, hla types and interferon. | 1977 | 876337 | |
| seroepidemiology of hepatitis b virus in israel. results of a pilot study in jerusalem. | one thousand thirty-three native and immigrant israelis, divided into 10-year age groups, were tested for the hepatitis b surface antigen (hbsag) and antibody (anti-hbs). the prevalence of anti-hbs was 10.1%, increasing with age from the first (6.3%) through the fifth decade (16.2%) and declining slightly in the sixth and seventh decades. the age-adjusted prevalence of anti-hbs was higher for native arabs (20.8%) compared with native jews (4.8%), and for immigrants from north africa (33.3%), com ... | 1977 | 879163 |
| etiology of sporadic hepatitis b surface antigen-negative hepatitis. | we studied serologically 45 adults who had sporadic acute viral hepatitis that was hepatitis b surface antigen (hbsag) negative. two cases were due to hepatitis b virus, as demonstrated by the appearance of antibody to hepatitis b core antigen. in three other patients, the serologic pattern was inconclusive. of 40 non-b cases, 20 were type a hepatitis and 20 were non-a, non-b hepatitis. clinically, type a and non-a, non-b hepatitis were indistinguishable; one case of fulminant disease occurred i ... | 1977 | 879615 |
| vertical transmission of the virus of hepatitis b and neonatal hepatic cirrhosis in an argentine family. | in a family in which the mother was a healthy hbsag and anti hbc carrier, and the father had a chronic persistent hepatitis with anti hbs and anti hbc positive, the development of neonatal cirrhosis in two of the children was proved to be present. one of the girls was an anti hbs carrier (anti hbc was not determined) and the other had positive anti hbs and anti hbc. both died and the diagnosis of cirrhosis was confirmed. the two healthy daughters were anti hbc carriers. | 1977 | 883464 |
| [transmission of bacterial and viral (hepatitis b virus) infections during endoscopy of the upper gastrointestinal system]. | 1977 | 888134 | |
| host responses to hepatitis b infection in patients in a chronic hemodialysis unit. | host responses to hepatitis b infection were studied in 222 patients in a chronic hemodialysis unit. from 1970 to 1976, patients were monitored monthly for development of hepatitis b surface antigen (hbsag), antibody to hepatitis b surface antigen (anti-hbs), and serum transaminase (sgpt) elevations. five categories of patients were identified as: 1) chronic carriers of hbsag; 2) transiently hbsag(+), who developed anti-hbs; 3) hbsag(-) on admission, who developed anti-hbs without becoming hbsag ... | 1977 | 894916 |
| [contact lens-fitting, a hepatitis risk? (author's transl)]. | hepatitis-b-antigen has been demonstrated by the radioimmunologic method in 5 out of 40 patients with acute or chronic hbs-antigen-positive hepatic disease. the importance of this finding as to the transferral of hepatitis by the fitting of contact lenses and its consequences are discussed. | 1977 | 894974 |
| hepatitis b virus in nucleoli of liver cells. | 1977 | 895812 | |
| accidental transfusion of blood containing hbsag or anti-hbs. | the presence of hbsag and anti-hbs was tested in 2,099 surgery patients and in the blood left in 3,157 flasks after transfusion. it was found that accidental transfusion of hbsag-containing blood had occurred. the 30 patients in which seropositivity correlations between recipients and transfused blood could be established were followed up clinically and serologically at 3, 6 and 12 months after transfusion. out of the 13 initially seropositive patients 5 showed clinical or subclinical symptoms o ... | 1977 | 898652 |
| liver involvement in the syndrome of mixed cryoglobulinemia. | a study of liver abnormalities in 36 patients with mixed cryoglobulinemia in the absence of underlying infectious, connective tissue, or lymphoproliferative disorders revealed clinical or biochemical evidence of liver dysfunction in 84%. hepatomegaly was detected in 77%, splenomegaly in 54%, and abnormalities in bilirubin, alkaline phosphatase, or serum glutamic oxalacetic transaminase in 77%. only four of the patients had overt liver disease. of 15 biopsies from 12 patients, there was normal ti ... | 1977 | 900672 |
| [studies of diseases caused by hepatitis b virus on the island of favignana]. | 731 serum samples were drawn from inhabitants of favignana (egadi islands, total population 3,000). presence of hbsag and anti hbs was tested by r.i.a. although only two cases of b virus hepatitis had been observed in the last 3 years, the overall positivity for hbsag was 4.8% and for anti hbs 31.6%, showing a distribution by age and sex comparable to that observed in similar studies. the rather high prevalence of hbsag in males over 70 deserves further investigations. | 1977 | 901639 |
| [fecal and oral transmission of hepatitis virus type b among patients on the territory of lasva and upper vrbas]. | 1977 | 904379 | |
| [frequency of anti-hbsag in personnel employed in some hospital departments and services with high risk of contact with hepatitis b virus]. | 1977 | 905721 | |
| antibodies to hepatitis b surface and core antigens in haemophiliacs and their contacts among hospital personnel. | in a group of 65 haemophilia patients one was a chronic carrier of hepatitis b surface antigen (hbsag) and the remaining 64 patients had antibody to hepatitis b surface antigen (anti-hbs). the antigen carrier and 63 of 64 haemophiliacs with anti-hbs also had antibody to hepatitis b core antigen (anti-hbc). in a second group consisting of 6 younger haemophiliacs, whose treatment with clotting-factor concentrates was started after the initiation of hbsag tests of all blood products, 3 showed evide ... | 1977 | 905782 |
| hepatitis b surface antigen and e antigen in pleural effusion: a case report. | hepatitis b e antigen (hbeag) and hepatitis b surface antigen (hbsag) were demonstrated in pleural fluid obtained from a 40-year-old dialysis patient who had hbsag and hbeag in her serum. the titers of hbsag and hbeag were similar in serum and pleural fluid. examination of the pleural fluid by electron microscopy revealed the presence of intact hepatitis b virus particles. these findings underline the potential hepatitis b virus infectivity of other body fluids besides blood, especially for medi ... | 1977 | 908498 |
| persistence of serum antibody to hepatitis b core antigen. | the purpose of the present study was to measure the amount of antibody to hepatitis b core antigen (anti-hbc) in different populations by the immunoelectroosmophoresis method. high titers of anti-hbc, up to 1/4,096, were found in the acute stage of hepatitis b virus infections and in the chronic carrier state of hepatitis b surface antigen. in cases of acute hepatitis the anti-hbc titers gradually declined to low levels but persisted for the observation time of 5 to 6 years. individuals positive ... | 1977 | 908743 |
| detection of e antigen during acute and chronic hepatitis b virus infections in chimpanzees. | 1977 | 908851 | |
| hepatitis b e antigen and infectivity of hepatitis b virus. | for confirmation of the difference in the infectivity of hepatitis b surface antigen (hbs ag)-positive serum according to differences in the e antigen system, four chimpanzees were inoculated with serum positive for hepatitis b e antigen (hbe ag), and three chimpanzees were inoculated with serum positive for antibody to hbe ag (anti-hbe). since the infectivity titrations are not yet completed, the end infectivity titer of each serum is not known. all four chimpanzees given injections of 10(-1), ... | 1977 | 908854 |
| hepatitis b e antigen and antibody activity in hepatitis b virus infection. | groups of institutionalized subjects, volunteer blood donors with serologic evidence of asymptomatic hepatitis b virus infection, and patients with acute type b viral hepatitis were studied for the presence of hepatitis b e antigen and antibody in a sequential manner over a period of two to three years. hbeag was detected in 9.5% of institutionalized residents and volunteer blood donors and in 24% of patients with acute type b viral hepatitis. hbeag positive subjects frequently had persistently ... | 1977 | 908972 |
| hla antigens and hepatitis b virus. | 1977 | 909570 | |
| [type b viral hepatitis. recent findings]. | the discovery of hepatitis b surface antigen by blumberg in 1965 offered a specific marker that could readily be employed in the clinical, epidemiological and experimental investigation of type b viral hepatitis. it has since been followed by the continuous gathering of further knowledge concerning this disease. the morphology and immunological and biochemical features of virus b, the epidemiology and prevention of hepatitis b, and marker determination techniques are examined in an overview of t ... | 1977 | 909638 |
| hepatitis-b virus infection in anaesthetists. | to determine whether anaesthetists are at risk from developing hepatitis-b virus (hbv) infection from their patients, 95 anaesthetists working with black south africans (who have a high prevalence of hepatitis-b antigenaemia) were questioned about attacks of viral hepatitis and their blood was tested for hepatitis-b (surface) antigen (hbsag) and antibody (anti-hbs). anti-hbs was detected in the serum of 17.9% of the anaesthetists, but none was a chronic carrier of hbsag. two anaesthetists had su ... | 1977 | 911589 |
| prevention of hepatitis b in hemodialysis patients using hepatitis b immunoglobulin. a controlled study. | in a controlled study, the protection effect of hepatitis b immune globulin (hbig) was evaluated in patients hemodialyzed for less than one month in two collaborating units. fifteen randomly selected patients received hbig at five to eight week intervals throughout the study, and 13 other control patients received no immunoglobulin. during a follow-up period of 14 to 30 months, none of the hbig-treated and 12 of the control patients developed evidence of exposure to virus b hepatitis, including ... | 1977 | 912951 |
| [theoretical, methodological and practical problems of virus disinfection in human medicine (author's transl)]. | 1977 | 914312 | |
| [immunology of hepatitis b virus infection]. | 1977 | 917936 | |
| [hbv (hepatitis b virus) infection through the birth canal]. | 1977 | 587187 | |
| e antigen and antibody in outbreaks of hepatitis b in two renal dialysis units. | in two renal dialysis units which had outbreaks of hepatitis b, patients were studied for the presence of e antigen and antibody. in one unit, in which the illness was mild and most of the patients (78%) became carriers of hbsag, all but one patient had e antigen. most of the hbsag carriers had persisting e antigen and most of the transient patients had also transient e antigen. in the other unit, in which the illness was more severe, none of the patients became a carrier. only 30% had e antigen ... | 1977 | 599184 |
| the infant and hepatitis b virus infection. | hbv has been shown to be responsible for a broad spectrum of disease in infants although most are asymptomatic carriers with mild transaminase elevation and unresolved hepatitis on liver biopsy. maternal-infant transmission is responsible for most infections. blood product infusion should become less significant. acute maternal hepatitis in the perinatal period results in asymptomatic infant infections at rates far exceeding transmission from asymptomatic carrier mothers. carrier mothers with th ... | 1977 | 602864 |
| humoral and cell-mediated immunity to hepatitis b virus antigens in acute and chronic liver disease. | the humoral immune response to hepatitis b virus antigens and the cell-mediated immunity to hepatitis b surface antigen (hbsag) were investigated in 12 healthy persons and 56 patients with various liver diseases. in patients with acute viral hepatitis type b, anti-hepatitis b core antigen was present constantly in serum in all phases, and after clinical recovery simultaneously with anti-hbs. a transitory cellular immune response to hbsag was demonstrated at the time the antigen was cleared, whil ... | 1977 | 605351 |
| [epidemiologic study of chronic hepatitis in relation to heptatis b virus infections (author's transl)]. | in order to evaluate the role of hepatitis b virus (hbv) in the etiology of chronic liver diseases, paired sera of 143 patients with biopsy-documented chronic hepatitis were tested for hbsag and anti-hbs by radioimmunoassay method. hbsag was detected in 67.3% of patients with a preceding verified eipsode of acute hepatitis, and in 26.7% of patients with a cryptogenic form of chronic hepatitis. hbsag was not found in any of patients with alcoholic chronic hepatitis and in only two of 18 patients ... | 1977 | 616263 |
| [hepatitis b antigen (hbsag) in hospitalized children]. | blood samples of 1940 hospitalized children aged 0--18 years were investigated for presence of hbs-ag by counter-electrophoresis, haemagglutination and radioimmunoassay, hbs-ag was found in 1.34% of all patients, being distributed evenly amongst boys and girls. the incidence was 1.7% in patients from a large university children's hospital and 0.6% in patients from a group of regional hospitals. of 26 samples positive by radioimmunoassay, 1 only was found positive by insensitive counter-electroph ... | 1977 | 617959 |
| distribution and persistence of hepatitis b surface antigen and antibody in a melanesian population. | the population of graciosa bay, santa cruz, british solomon islands protectorate, was tested for hbsag and anti-hbs in 1973 and 1974. both the antigen and antibody occurred more often in males, presumably due to a higher exposure rate. none of 28 infants under one year of age had antigen and only one of 50 individuals under two years (2%) did. the prevalence of antigenemia was higher in older children and did not decline with increasing age. this pattern is contrasted to that found in other popu ... | 1977 | 835561 |
| limited family clustering of hepatitis b surface antigen in a melanesian population. | the entire population of graciosa bay, santa cruz, solomon islands, was tested for hepatitis b surface antigen (hbsag) by reverse passive hemagglutination and antibody to hbsag (anti-hbs) by passive hemagglutination. analysis of the distribution of hbsag in relatives of hbsag carriers and non-carriers showed clustering only in children of carrier mothers. similarly, there was no clustering of total exposure as measured by serologic tests except in children of carrier parents primarily due to the ... | 1977 | 835562 |
| epidemiology of hepatitis b in two alaska communities. | in 1973, epidemiologic and serologic data related to hepatitis b infection were collected from the residents of two remote alaskan eskimo villages located in an area of high hepatitis incidence. a total of 418 sera were tested by solid-phase radioimmunoassay for heaptitis b surface antigen (hbsag) and antibody to that antigen (anti-hbs). the overall infection prevalence of 54.8% in the two villages included a 13.9% prevalence of hbsag and a 40.9% prevalence of anti-hbs. families containing an in ... | 1977 | 835563 |
| transmission of hepatitis b virus to gibbons by exposure to human saliva containing hepatitis b surface antigen. | a pool of whole-mouth saliva collected from five human carriers of hepatitis b surface antigen, subtype adr, was found to contain antigen particles with mean diameters of 23.3 and 41.8 nm as seen by immune electron microscopy. two gibbons received subcutaneous injections of the pooled saliva and developed serological and, in at least one animal, biochemical evidence of hepatitis b virus infection at 12 and 22 weeks, respectively. although none of eight other gibbons that were exposed by the nasa ... | 1977 | 833450 |
| australia antigen--a fresh approach. | 1977 | 614407 | |
| dna synthesized in the hepatitis b dane particle dna polymerase reaction. | radioactive dna was prepared in extensive (4 h) dane particle dna polymerase reactions. in different experiments the amount of new dna, determined by the amount of nucleotide incorporation into an acid-insoluble form, was between 29 and 45% of the total circular dna isolated from dane particle preparations after the reaction. dna reassociation kinetics were used to determine the complexity of the newly synthesized dna. in different experiments cot1/2 values, corresponding to between 625 and 1,25 ... | 1977 | 833933 |
| hepatitis b virus infection on taiwan. | 1977 | 757978 | |
| [significance of australia antigen in the differential diagnosis and prognosis of hepatitis]. | the australia-antigen (hbsag) is a simple detectable marker of an infection with hepatitis b virus. by demonstration of hbsag an acute hepatitis b can be differentiated from other forms. likewise the detection of hbsag in chronic active hepatitis can differentiate the viral induced type from the autoimmune type. hbsag is important with respect to the prognosis of an acute hepatitis b, because persistence for some months points at a transition to chronic hepatitis. | 1977 | 844784 |
| infectivity of purified hepatitis b virus particles. | 1977 | 834202 | |
| serological evidence of hepatitis b infection in patients with chronic liver diseases: radioimmunoassay of hbsag and anti-hbs. | the prevalence of hepatitis b surface antigen (hbsag) and anti-hbs was determined by a sensitive double-antibody radio-immunoassay technique in a series of patients with chronic liver diseases. hbsag was demonstrated in 37 out of 98 consecutive patients with chronic hepatitis (38%) and in 14 out of 108 patients with non-alcoholic cirrhosis (13%). hbsag was not found in any of the patients with steatosis, alcoholic cirrhosis, or primary biliary cirrhosis. in the patients with chronic hepatitis hb ... | 1977 | 918556 |
| [towards an effective vaccine against viral hepatitis b]. | 1977 | 918937 | |
| [antibodies against hbs antigens as identified using the radioimmunologic method]. | antibodies to hepatitis bs antigen identified only by radioimmunoassay, which is 8000 times more sensitive than counterelectrophoresis, were found in blood donors in 17%, in the haemodialysis centre in 44%, in the patients of this centre in 47%. hbsag and the antibodies have been tested in different series of albumin and gammaglobulin. immunoglobulin anti hbs was prepared by the blood transfusion centre in ljubljana, and the imunoloski zavod in zagreb, and the problem of prevention, and producti ... | 1977 | 921732 |
| the clinicopathological features of the alcoholic liver injury in japan and its etiological relationship to hepatitis b virus. | clinicopathological features of 73 patients with alcoholic liver injury were investigated and its etiological relationship to hbv was examined. the results obtained are as follows: 1) the symptoms and histologic changes observed in this study were slightly differed from that of acute alcoholic hepatitis reported in the united states and european countries and only few cases showed similar symptoms and histologic changes compatible to acute alcoholic hepatitis. 2) histologically, the pattern of h ... | 1977 | 924088 |
| identification of blood stains by non-genetic characteristics: the hbs antigen of viral hepatitis b. | in forensic cases, until recently, identification of biological stains was based on the use of genetic markers, such as blood groups. in this paper, we show that another acquired characteristic, even if not immutable during life, may afford similar possibilities. as an example, we have demonstrated that the hbs antigen, associated with the hepatitis b virus, can help in the identification of bloodstains. the requisite condition for using this new marker, is that not too much time should elapse b ... | 1977 | 924317 |
| [hepatitis b virus and gianottie grosti syndrome, with special reference to multiple incidences in the matsuyama area]. | 1977 | 926368 | |
| [cell-mediated immunity to surface and core antigens of type b hepatitis virus. ii. studies of persons exposed to infection]. | 1977 | 926897 | |
| [immunological aspects of acute viral hepatitis treated with corticosteroids]. | acute viral b-hepatitis is the consequence of an effective specific immune response against the hepatitis b-virus with elimination of the virus. corticosteroids decrease this immune reaction and thereby inhibit virus elimination. in principle, therefore, corticosteroid therapy promotes a transition to chronicity. this theoretical concept is documented practically by 8 patients treated with steroids in the early phase of acute viral hepatitis. transition to some form of chronic liver disease is d ... | 1977 | 929138 |
| radioimmunoassay of hepatitis b core antigen and antibody with autologous reagents. | anti-hbc is the most sensitive indicator of current or recent hepatitis b virus infection, hence its detection is valuable in laboratory diagnosis of the infection. dane particles isolated from the plasma of a single chronic carrier and his autologous igg labeled with 125i were utilized in a solid-phase sandwich radioimmunoassay for anti-hbc. the principle of serologic neutralization of core antigen and consequent inhibition of binding of the cores to the solid-phase rendered the method to be a ... | 1977 | 930050 |
| prevalence and epidemiologic significance of antibody to hepatitis b core antigen in greece. | the diagnostic and epidemiologic significance of antibody to hepatitis b core antigen (anti-hbc) detected by complement fixation was studied in a sample of 412 healthy persons, 0-70 years old of both sexes living in the athens area. the prevalence of hepatitis b virus (hbv) infections was found to be very high (26.5%) and the hepatitis b surface antigen (hbsag) carrier rate (4.1%) among the highest in europe. anti-hbc was detected in 63 (15.3%) of the examined infection. the prevalence of anti-h ... | 1977 | 930920 |
| [new markers of hepatitis b virus. diagnostic and prognostic value]. | 1977 | 834546 | |
| [permeability of dialysis membranes for hepatitis-b virus: on the prophylaxis of hepatitis in a haemodialysis centre (author's transl)]. | dialysis fluids of two hepatitis-bs (hbs) antigen-positive dialysis patients were tested for hepatitis-b virus. total dialysate volume of 5.5 litres each - as obtained on haemodialysis with the redy-recirculation system - was concentrated by ultrafiltration and trap and rate-zonal ultracentrifugation, followed by fractionation, and purified. electron-microscopic evidence of permeability of an intact dialysis membrane for hepatitis-b was obtained. concentration of hepatitis-b virus was at least 1 ... | 1977 | 830518 |
| hepatitis and hepatitis b-antigen in greenland. ii: occurrence and interrelation of hepatitis b associated surface, core, and "e" antigen-antibody systems in a highly endemic area. | the distribution of hepatitis b surface antigen and antibody (hbsag and anti hbs), hepatitis b core antibody (anti-hbc), and the heaptitis b associated "e" antigen-antibody system (hbeag and anti-hbe) were studied in three areas in greenland previously shown to be endemic for hepatitis b. overall prevalence of hbsag and anti-hbs ranged from 47 - 81%, thus confirming the existence of a hyperendemicity of the hepatitis b agent in some polar areas. anti-hbc occurred closely correlated to hbsag and ... | 1977 | 835567 |
| [progress in viral hepatitis]. | 1977 | 875715 | |
| viral hepatitis type b during pregnancy, the neonatal period, and infancy. | eighteen women who developed type b hepatitis late in pregnancy or early in the postpartum period (groups i and ii), 12 women who were chronically infected with the hepatitis b virus (groups iii and iv), and 32 of their offspring were tested for hepatits b surface antigen, antibody to the hepatitis b surface antigen, antibody to the hepatitis b core antigen, and the recently discovered hepatitis b-associated e antigen and its antibody. twelve of 18 infants born to group i and group ii mothers a ... | 1977 | 839328 |
| progress with hepatitis b virus-editorial review. | 1978 | 18748146 | |
| biological activity of hepatitis b antigens in cell culture. | direct interference by purified hepatitis b surface antigen or virus particles was not demonstrated in tissue culture. significant levels of interferon were not induced. the surface antigen did not block the adsorption of other viruses. | 1978 | 569686 |
| hepatitis b virus infections among danish dentists. | since type b hepatitis is generally regarded as an occupational risk for dentists, the participants at the 1976 annual meeting of the danish dental association were examined for hepatitis b surface antigen (hbsag) and antibody to hbsag (anti-hbs). a total of 1,338 dentists (89% of the dentists at the meeting and 29% of all danish dentists) were included in the study by completion of a questionnaire and by radioimmunoassay of a blood sample for hgsag and anti-hbs. none of the dentists was hbsag-p ... | 1978 | 624852 |
| hepatitis b virus and primary liver cancer. | 1978 | 618428 | |
| [intrahospital transmission of hepatitis b virus]. | 1978 | 734508 | |
| containment of hepatitis b virus infection in a hemodialysis unit. | the unsuspected introduction of a carrier of hepatitis b virus into a hepatitis-free hemodialysis unit coincided with a routine serologic survey in early april 1976. thus the prevalence of hepatitis b surface antigen and its antibody was known for the 42 patients and 23 personnel at risk. control consisted of isolating the patient identified as a carrier seven days after admission. immune globulin was not given to potentially exposed persons. during a 15-month period, only one case of icteric he ... | 1978 | 739161 |
| prevalence of antibody to hepatitis b virus in melbourne. | 1978 | 739922 | |
| the liver as a barrier against antigens in viral hepatitis infection. | 1978 | 740042 | |
| viral hepatitis: lack of transmission in an athenian school. | in the 1975-76 school year, 3 cases of icteric hepatitis occurred almost simultaneously in 2 grades of an athenian school. an initial survey of the 2 classes approximately one week later found that 88 of 94 children were susceptible to type a hepatitis. no further clinical cases occurred. a second survey at the end of the school year revealed only 2 subclinical hepatitis a virus infections: one coincident with the overt cases in november, and a second from extramural exposure in february. two ca ... | 1978 | 744672 |
| spontaneous resolution of severe aplastic anemia associated with viral hepatitis a in a 6-year-old child. | recovery from acquired aplastic anemia associated with hepatitis is rare. this case of a 6-year-old boy with severe aplastic anemia is the first reported association of this disease with a hepatitis a infection. antibody to hepatitis a (anti-ha) was not detected on admission, but was detected three weeks later. infection with hepatitis b virus, cytomegalovirus (cmv), and epstein-barr virus (ebv) were excluded. the peak titer of anti-ha was higher than would be expected for passive transfer of an ... | 1978 | 752262 |
| urticaria associated with acute viral hepatitis type b: studies of pathogenesis. | to determine whether skin deposition of circulating immune complexes contributes to prodromal urticaria of acute hepatitis b, we studied two patients with hepatitis b who presented with urticaria and fever. during the urticarial prodrome but not thereafter, we found activation of both classic and alternative complement pathways. hepatitis b surface antigen (hbsag)-antibody complexes were identified (by electron microscopy) in cryoprecipitates from both patients and igg (by immunodiffusion) in cr ... | 1978 | 352219 |
| duality of hepatitis b e antigen in serum of persons infected with hepatitis b virus: evidence for the nonidentity of e antigen with immunoglobulins. | hepatitis b e antigen (hbeag) is detected in the serum of some persons infected with hepatitis b virus. owing to a close correlation of hbeag and hepatitis b virus in the serum, it has been used as a practical indicator of infectivity. two entities of hbeag activity physicochemically different from each other were demonstrated in the serum of persons infected with hepatitis b virus. one was associated with a molecule that precipitated in 1.33 m ammonium sulfate solution, was larger than igg, and ... | 1978 | 273922 |
| [antigenic e system in hepatitis b virus-induced infection]. | 1978 | 358161 | |
| immune mechanisms and the action of interferon in chronic hepatitis b virus infection. | cytotoxic t lymphocytes can eliminate cells infected with hepatitis b virus. a defect of t lymphocyte-mediated cytolysis seems to exist in chronic hepatitis b infection. t cell-mediated lysis is dependent on hla antigens of the infected host and this may explain the increased or decreased frequency of particular hla antigens in chronic carriers of hepatitis b virus. this virus may decrease the concentration of hla antigens expressed on liver cells. interferon increases the hla antigen expression ... | 1978 | 352919 |
| drug therapy reviews: chronic hepatitis. | the classification, clinical course, etiology and treatment of chronic hepatitis are discussed. the clinical manifestations of chronic hepatitis are of limited diagnostic use. diagnosis must be made by liver biopsy. the disease is classified as chronic persistent or chronic active hepatitis. the prognosis for chronic persistent hepatitis is excellent, and no treatment is required. chronic active hepatitis may progress to cirrhosis and is associated with a poor prognosis if untreated. recognized ... | 1978 | 358829 |
| [morphologic and biophysical study of serum hepatitis transfection]. | 1978 | 366901 | |
| liver biopsy in chronic hepatitis: 1968-78. | the classification of chronic hepatitis introduced in 1968 is still current, but has been modified. the concept of bridging hepatic necrosis has been incorporated, and is recognised as an important feature of both acute and chronic aggressive (active) hepatitis (cah). in the pathogenesis of the latter, piecemeal necrosis is, however, thought to be the more important factor. the histological picture of cah varies widely. several causes of cah have been identified, including hepatitis b virus. rec ... | 1978 | 355068 |
| e antigen in the serum of hbs antigen-positive patients on maintenance dialysis and after transplantation. | the 'e antigen' (eag) is specifically associated with hepatitis b virus infections and appears to be a marker for the infectivity and a prognostic indicator of the chronicity of liver disease. therefore we examined by immunodiffusion the presence of eag in the seum of hbsag-positive patients on maintenance dialysis. the dialysis patients had a significantly higher incidence of positive eag compared with a group of unselected hbsag-positive patients without renal failure. in most of the dialysis ... | 1978 | 368777 |
| [pathology of hepatitis and liver cirrhosis in idiopathic cryoglobulinemic syndromes. clinical, casuistic and histopathological contribution]. | 1978 | 347545 | |
| [gianotti disease and hepatitis b virus (author's transl)]. | 1978 | 310483 |