Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| comparison of 4 serological tests--complement fixation, neutralization, fluorescent antibody to membrane antigen and immune adherence hemagglutination--for assay of antibody to varicella-zoster (v-z) virus. | four tests for antibody to varicella-zoster (v-z) virus were compared; these were tests of complement fixation (cf), neutralization (nt), fluorescent antibody to membrane antigen (fama) and immune adherence hemagglutination (iaha). fifty-two sera from patients with varicella and zoster and from recipients of live varicella vaccine were examined by the 4 tests. the cf test was least sensitive, but the antibody titers by the nt, fama and iaha tests were roughly comparable. the iaha test was the si ... | 1979 | 231433 |
| studies on the polypeptides of varicella-zoster (v-z) virus. 1. detection of varicella-zoster virus polypeptides in infected cells. | virus-induced polypeptides in cells infected with varicella-zoster virus (vzv) were analyzed by sds-polyacrylamide gel electrophoresis (sds-page) and autoradiography. when human embryonic lung (hel) cells infected with the oka strain of vzv were labelled with 35s-methionine or 14c-glucosamine from 40 hr to 46 hr after infection, at least 18 vzv-induced polypeptides and 10 glycoproteins could be identified in the infected cells. the molecular weights of the polypeptides and glycoproteins ranged ... | 1979 | 231438 |
| comparative study of herpes group virus-induced dna polymerases. | a comparative biochemical study of virus-induced dna polymerases was made among the herpes group viruses: namely, herpes simplex virus (hsv) type 1 and type 2, human cytomegalovirus (hcmv) and varicella-zoster virus (vzv). although these virus-induced enzymes shared some biochemical properties, they differed in several important aspects. all these virus-induced dna polymerases could efficiently use poly(dc) . oligo(dg)12--18 and poly(da) . oligo(dt)12--18 as template-primers. however, in phospho ... | 1979 | 231586 |
| serological studies on the antigenic relationship between herpes simplex virus and varicella-zoster virus. | if crossreacting antibodies between varicella-zoster virus (vzv) and herpes simplex virus (hsv) exist, one would expect more positive reactions with vzv in a group of hsv positive patients than in a group of hsv negative patients. this statement can only apply to a group of individuals where positive and negative reactions with respect to hsv and vzv are evenly distributed. such a distribution can only be found among children. therefore, the relationship between hsv-1 and vzv was the only one wh ... | 1979 | 232073 |
| a serological survey of st lucia. | a serological survey of a random sample of 541 of the population of st lucia was undertaken. the prevalence of antibodies to dengue, herpes virus, vz, rotavirus, rubella and syphilis is described and compared with other communities. | 1979 | 232090 |
| the serological relationship of varicella-zoster virus to other primate herpesviruses. | the serological relationship between viruses producing varicella-like exanthems in several subhuman primates, varicella-zoster virus (vzv) and herpes simplex viruses (hsv) types 1 and 2, was investigated. all the primate viruses were related to vzv and some to hsv also. these results show that there is a group of varicella viruses, comprising four distinct entities, some of which may be useful for the establishment of an animal model for varicella. | 1979 | 232132 |
| infection and persistence of varicella-zoster virus in lymphoblastoid raji cell line. | infection of raji cells by varicella-zoster virus (vzv) resulted in permissive infection with establishment of a persistently infected lymphoblastoid cell line. vzv antigens of the membrane and nuclear type, as detected by the indirect immunofluorescence membrane antigen (ifama) and anticomplement immunofluorescence (acif) tests, were observed. minute amounts of infectious virus were detected by co-cultivation of vzv-infected raji cells (raji-vzv), with permissive human embryo fibroblasts (hef). ... | 1979 | 232537 |
| appearance of immunoglobulin g fc receptor in cultured human cells infected with varicella-zoster virus. | after infection with varicella-zoster virus, hela and human embryo lung cells developed a receptor for the fc portion of human and rabbit immunoglobulin g. the receptor was detected by both hemadsorption and immunofluorescence, using antibody-coated erythrocytes and heat-aggregated immunoglobulin g. however, sheep erythrocytes sensitized with f(ab')2 of anti-sheep erythrocyte antibody did not adsorb to the receptor. when cell-free varicella-zoster virus was inoculated into the hela cell monolaye ... | 1979 | 232695 |
| complement fixing antibody to varicella-zoster virus in cancerous patients. | the titer of complement fixing antibody to varicella-zoster virus was studied in sera from 161 cancerous patients and 161 healthy controls. sera with antibody titers greater than or equal to 1/4 were 74 (45.9%) among cancerous patients and 120 (74.5%) among healthy controls. the difference between these two groups is statistically significant. | 1979 | 233341 |
| [serological survey for virus and mycoplasma infections (author's transl)]. | the authors describe the two years follow up of complement fixing antibodies vs 4 viral antigens (herpes simplex, herpes zoster, cytomegalovirus, respiratory syncytial virus, mycoplasma pneumoniae). they evaluate the seasonal trend and the eventual clinical correlations on 3267 sera and 254 spinal fluids from hospitalized patients. | 1979 | 233415 |
| analysis of late infections in 89 long-term survivors of bone marrow transplantation. | 1979 | 34408 | |
| zoster immune globulin prophylaxis of disseminated zoster in compromised hosts. a randomized trial. | herpes zoster can be a severe, and sometimes fatal, virus infection in its disseminated form in immunocompromised hosts. previous studies have suggested that delay in appearance of antibody to varicella-zoster virus occurs as one defect in such patients. in this study, pooled gamma-globulin (normal serum globulin [nsg]) and zoster immune globulin ([zig] prepared from convalescent zoster patients) were compared for their ability to prevent dissemination of early localized zoster in immunocompromi ... | 1980 | 6153260 |
| live attenuated varicella-zoster vaccine. | varicella-zoster (vz) virus causes two diseases, varicella and zoster. because it was recognized that, after varicella, latent vz virus persisted in the host and because varicella was thought to be a milde disease, there was little impetus in north america to develop a live vz vaccine. more recently, it has become apparent that currently available methods of prevention and treatment of severe varicella are not always efficacious. with the development of a live attenuated vz vaccine by takahashi ... | 1980 | 6158080 |
| ineffectiveness of adenine arabinoside and adenine arabinoside 5'-monophosphate in simian varicella infection. | adenine arabinoside and adenine arabinoside 5'-monophosphate (ara-amp) have been evaluated for antiviral activity against simian varicella virus infection in monkeys. in a preliminary study for toxicity, intramuscular injection of ara-amp at 15 mg/kg per day as a single injection for 5 days to two normal patas monkeys caused no detectable local reaction, no weight loss or changes in serum transaminase levels, and no hematological abnormalities. when this dose was given in the treatment of four s ... | 1980 | 6158291 |
| abolished production of interferon by leucocytes of patients with the acquired cytogenetic abnormalities 5q -- or -- 5 in secondary and de-novo acute non-lymphocytic leukaemia. | interferon production by leucocytes on stimulation with inactivated antigens from herpes simplex virus, varicella zoster virus and cytomegalovirus was determined in 19 patients with preleukaemia or acute non-lymphocytic leukaemia, in 15 following treatment for other tumours. production of interferon was abolished in 10 patients and preserved in nine cases after stimulation with herpes simplex antigen. cytogenetic studies of bone marrow demonstrated an abnormal karyotype in 13/15 patients with se ... | 1980 | 6158987 |
| human anti-chickenpox immunoglobulin in the prevention of chickenpox. | human anti-chickenpox immunoglobulin (zoster immune globulin, zig) was largely ineffective in preventing infection in forty-three high-risk contacts of chickenpox. twenty-nine of these non-immune infants and children who had been in close contact with cases of varicella became infected, and symptoms developed in twenty-four. since zig may modify chickenpox it should continue to be given to high-risk contacts until the availability of a simple and sensitive test makes it possible to identify thos ... | 1980 | 6101802 |
| zoster immune globulin for immunosuppressed children. | 1980 | 6103108 | |
| varicella-zoster virus affecting immigrant nurses. | 1980 | 6105332 | |
| prospects for new viral vaccines. | animal virology has made outstanding contributions to preventive medicine by the development of vaccines for the control of infectious disease in man and animals. cost-benefit analysis indicates substantial savings in health care costs from the control of diseases such as smallpox, poliomyelitis, yellow fever and measels. areas for further development include vaccines for influenza (living, attenuated virus), the herpes group (varicella: cytomegalovirus), respiratory syncytial virus, rotavirus a ... | 1980 | 6106250 |
| unusual herpes viral disease. | 1980 | 6107512 | |
| cell-mediated immunity to varicella-zoster virus as assessed by the migration inhibition test. | the migration inhibition method was used to test cell-mediated immunity to varicella-zoster (vz) virus in 10 varicella and 11 herpes zoster patients. control groups consisted of eight children susceptible to vz infection on serological evidence and 49 normal persons of different age categories. depending on the positivity criterion adopted, positive results during disease were obtained in 43% or 90% or all tests performed in varicella patients and 47% or 74% in herpes zoster patients. irrespecti ... | 1980 | 6111201 |
| [a quantitative immunofluorometric assay for alpha-fetoprotein and antibodies to varicella-zoster virus in human serum (author's transl)]. | 1980 | 6166775 | |
| cell-mediated and humoral immunity to herpesviruses during and after herpes zoster infections. | the influence of herpes zoster virus infection on cell-mediated and humoral immunity to varicella-zoster virus (vzv), cytomegalovirus, and herpes simplex virus (hsv) was followed in 17 zoster patients from the first week to 6 months after start of eruptions. the clinical responses were registered and correlated to the immune responses. a significant depression in blast transformation on stimulation of lymphocytes with all three antigens was found on days 1 to 5 compared with transformations late ... | 1980 | 6163709 |
| prevention of varicella in urgent cases by passive transfer of vaccine-induced immunity. | for the purpose of preventing spread of infection to high risk children whose immunities were severely impaired by intensive chemotherapy or for some other reason, when cases of varicella occurred in a children's ward or in a family, healthy adults (mothers and a doctor) were immediately given live varicella vaccine, blood was collected from these adults 5 to 7 days after vaccination and the whole blood or plasma including the buffy coat was transferred in the high risk children. subsequently th ... | 1980 | 6257226 |
| humoral and cellular immune response to varicella-zoster virus in children inoculated with live attenuated varicella vaccine. | twenty-seven hospitalized children without a history of varicella were vaccinated with 500 plaque forming units of live attenuated varicella vaccine (oka strain) and followed for four to five weeks at weekly intervals for the development of virus-specific cell-mediated immunity (cmi) and neutralizing (nt) antibody activity. these children had suffered from heterogeneous underlying diseases, such as acute leukemia, lymphoma, the nephrotic syndrome, and other chronic illnesses and were in various ... | 1980 | 6257227 |
| spread of varicella in hospitalized children having no direct contact with an indicator zoster case and its prevention by a live vaccine. | varicella spread from a child with zoster to a total of 3 susceptible infants in another room in a children's ward, although they had been strictly isolated. to prevent spread of the disease, the staffs and patients were doing their own washing and no source of natural infection could be found. the cases indicate that it is difficult to predict nosocomial varicella infection or to prevent spread of the disease simply by isolation in a children's ward. a total of 11 other children without history ... | 1980 | 6257228 |
| studies on the polypeptides of varicella-zoster (v-z) virus. ii. syntheses of viral polypeptides in infected cells. | synthesis of varicella-zoster virus (vzv)-induced polypeptide was examined at intervals after infection by immunoprecipitation, sds-polyacrylamide gel electrophoresis (page) and fluorography. human embryonic lung (hel) cells were inoculated with vzv-infected cells at a ratio of about 1 infected cell to 5 uninfected cells and pulse-labelled with 35s-methionine or 14c-glucosamine. under this experimental condition, virus-induced protein and glycoprotein began to appear 4 to 6 and 18 to 20 h after ... | 1980 | 6257229 |
| [changes in antibody titre after rubella vaccination in primarily rubella-sera positive parturient women. demonstration of antigen-specific (rubella) and non-specific stimulated antibody titres (author's transl)]. | 1980 | 6257468 | |
| varicella-zoster virus transformation of hamster embryo cells. | varicella-zoster virus infection of primary hamster embryo cells resulted in oncogenic transformation. these transformed cells exhibited virus-specific antigens by immunofluorescence and developed surface fc receptors. they induced aggressive fibrosarcomas when injected into inbred hamsters. the tumour-bearing hamsters develop antibodies to varicella-zoster antigens. | 1980 | 6257832 |
| radiology in inflammatory disease of the colon: an area of increased interest for the modern clinician. | 1980 | 6259078 | |
| herpes: scourge of the seventies. | 1980 | 6243084 | |
| phosphonoacetic acid induced persistence of varicella-zoster virus in cell culture. | 1980 | 6243413 | |
| zoster immune globulin. | 1980 | 6243457 | |
| the synthesis of glycoproteins in human melanoma cells infected with varicella-zoster virus. | 1980 | 6243815 | |
| herpes zoster and small cell bronchogenic carcinoma. | in nine of 74 (12 per cent) consecutive, previously untreated patients with small cell bronchogenic carcinoma receiving combination chemotherapy herpes zoster developed. this is the highest frequenzy reported for this viral infection in patients with nonlymphoproliferative solid tumors. cutaneous dissemination developed in six of the nine patients, but visceral involvement did not occur. the major difference between the patients with herpes zoster and those without was the superior duration of m ... | 1980 | 6243858 |
| varicella dendritic keratitis. | a 7-year-old boy and a 3-year-old girl suffered from unilateral disciform keratitis and iritis associated with varicella. while they were treated with topical corticosteroid, idoxuridine, and atropine drops, dendritic lesions typical of herpes zoster appeared four months after the onset of eruptive skin lesions. using the direct immunofluorescent method, we showed varicella-zoster virus antigen in the epithelial cells scraped from the dendritic lesion. | 1980 | 6243866 |
| transfer factor and cellular reactivity to varicella-zoster antigen in childhood leukemia. | 1980 | 6244113 | |
| atypical generalized zoster with lymphadenitis mimicking lymphoma. | 1980 | 6244490 | |
| pathogenesis of varicella-zoster angiitis in the cns. | a 20-year-old man with hodgkin's disease experienced ophthalmic zoster with dissemination and cns involvement. at autopsy, he was found to have granulomatous angiitis involving the basilar artery, and electron microscopy revealed virus-like particles in the outer layers of the vessel walls, but not the endothelium. this suggests that granulomatous angiitis of the cns in varicella-zoster infections results from direct viral invasion of blood vessels, perhaps by contiguous spread from cranial nerv ... | 1980 | 6244805 |
| enzyme-linked immunosorbent assay for detection of antibodies to varicella zoster virus. | a sensitive enzyme-linked immunosorbent assay (elisa) is described for detection of varicella zoster virus (vzv) igg antibodies. the antigen consisted of a sonicated extract of vzv-infected human embryo cells. goat antihuman igg peroxidase conjugate was used to detect human igg bound to viral antigen. the results have been compared with those obtained by the indirect peroxidase antibody to membrane antigen technique (ipama). comparison of titers obtained by elisa with those obtained by ipama in ... | 1980 | 6245042 |
| development and characteristics of the cellular immune response to infection with varicella-zoster virus. | techniques for assay of in vitro lymphocyte transformation (ltf) were used with varicella-zoster virus (vzv) as the antigen to study the temporal characteristics of the vzv-specific cellular immune response in children with varicella and in normal subjects with a history of the illness. the ltf response in children with only vesicular eruptions was prompt, and individual peak activity was detected within one to two weeks after the onset of illness, followed by a gradual decrease of the activity ... | 1980 | 6245148 |
| [varicella arthritis--a rare complication of varicella (author's transl)]. | 1980 | 6245348 | |
| circulating immune complexes and complement-fixing antibodies in patients with varicella-zoster infection. relationship to début of the disease. | serum samples from 32 varicella-zoster (vz)-infected patients were examined for circulating immune complexes (ic) within 1 1/2 week after début of the skin rash as well as during the following 5 weeks. three test systems were used: a complement consumption (cc) assay, a c1q solid phase (cu1-sp) assay and a polyclonal rheumatoid factor-binding (prf-i) assay. the cc and prf-i assays were the most effective in detecting large igg aggregates of ic, while aggregates of intermediate and small size wer ... | 1980 | 6245442 |
| varicella-zoster virus infection after marrow transplantation for aplastic anemia or leukemia. | nearly one-half of marrow transplant recipients who survive at least 6 months develop varicella-zoster virus (vzv) infection. of 92 cases studied, 82 occurred within the first 12 months after transplant. only one patient had recurrent infection. seventy-seven patients had herpes zoster, 22 with subsequent cutaneous dissemination, and 15 had varicella. the overall mortality rate was 8%, and all deaths occurred within 9 months of transplant. twenty-six of 32 patients studied had significant rises ... | 1980 | 6245486 |
| herpes zoster-varicella in cutaneous t-cell lymphomas. | the overall frequency of herpes zoster-varicella (hzv) infection in 221 patients with histologically confirmed cutaneous t-cell lymphoma was 10% (22 patients). the frequency of hzv infection and serious complications (viral dissemination, bacteremia) was relatively high in patients with evidence of extracutaneous involvement, especially in patients with sézary syndrome. the major factors identified to account for this predisposition to hzv infection include intensive treatment with radiation the ... | 1980 | 6245621 |
| cell-mediated immunity to varicella-zoster virus after allogeneic marrow transplant. | the cellular immune response of normal persons and marrow transplant recipients to varicella-zoster virus (vzv) antigen was measured with use of the lymphocyte transformation response. ninety-nine of 100 normal persons with previous vzv infection had a stimulation index of greater than or equal to 4.8, while 10 susceptible persons had responses of less than or equal to 3.0. before transplant, responses were lower than normal in patients with leukemia in relapse (p = 0.001), but not in patients w ... | 1980 | 6246177 |
| a varicella vaccine? | 1980 | 6246407 | |
| molecular epidemiology of dna viruses: applications of restriction endonuclease cleavage site analysis. | restriction endonucleases which cleave dna at specific nucleotide sequences can be used to produce a set of dna fragments of a viral genome which, when separated by gel electrophoresis, gives a characteristic "fingerprint" for that virus genome. this simple technique has been used to identify and classify dna viruses of the herpes, adeno, and papova virus groups. small variants within a given type (e.g., herpes simplex type i) are genetically stable and permit study and identification of individ ... | 1980 | 6246687 |
| herpes zoster pericarditis. | a healthy 22-year-old man developed acute varicella pericarditis, characterised by an enanthem with diagnostic rising titres of varicella zoster antibodies but without the typical exanthem. this, the third reported case of varicella pericarditis, is the first to be documented without a typical varicella eruption. | 1980 | 6246908 |
| [clinical aspects of vz viral hepatitis and the aggravating effect of herpes zoster on the course of infectious and serum viral hepatitis]. | 1980 | 6247538 | |
| varicella immunity in adults. | 1980 | 6247634 | |
| selective decline in cellular immune response to varicella-zoster in the elderly. | the incidence of herpes zoster rises markedly in the aged. we evaluated the hypothesis that cellular immunity to varicella-zoster (vz) viral antigens may be impaired in aged subjects. we found that the lymphocyte proliferation to vz antigen was less in older asymptomatic individuals than in normal young controls. in contrast, responses to other antigens did not differ. antibody titers to vz were similar in both young and old subjects. impairment of cellular immunity to vz, on a population basis, ... | 1980 | 6247671 |
| enzyme-linked immunosorbent assay for detection of virus-specific igm antibodies to varicella-zoster virus. | a sensitive enzyme-linked immunosorbent assay (elisa) is described for detection of varicella-zoster virus (vzv) igm antibodies. the antigen consisted of a sonically disrupted extract of vzv-infected human embryo cells. the tested sera were absorbed with staphylococcus aureus (strain cowan i) before analysis. rabbit anti-human igm peroxidase conjugate was used to detect human igm bound to viral antigen. the results were compared with those obtained by the indirect fluorescent antibody to membran ... | 1980 | 6248482 |
| [facial paralysis and varicella-zoster virus (vzv): serum antibody titer and vzv skin test (author's transl)]. | 1980 | 6248622 | |
| transfer factor for the prevention of varicella-zoster infection in childhood leukemia. | sixty-one patients with leukemia and no immunity to chickenpox were given dialyzable transfer factor or placebo and followed for 12 to 30 months in a double-blind trial designed to examine the clinical efficacy of transfer factor. sixteen patients in the transfer-factor group and 15 in the placebo group were exposed to varicella zoster, and most of them had a rise in antibody titer. chickenpox developed in 13 of 15 exposed patients in the placebo group but in only one of 16 in the transfer-facto ... | 1980 | 6248780 |
| therapeutic potential of transfer factor. | 1980 | 6248781 | |
| corticosteroids and varicella disciform keratitis. | 1980 | 6249122 | |
| active immunizations for adults. | 1980 | 6249188 | |
| 2'-fluoro-5-iodo-aracytosine, a potent and selective anti-herpesvirus agent. | a newly synthesized pyrimidine analog, 2'-fluoro-5-iodo-aracytosine (fiac), suppressed by 90% the replication of various strains of herpes simplex virus types 1 and 2 at concentrations of 0.0025 to 0.0126 microm. cytotoxicity was minimal, as determined by trypan blue dye exclusion with norman vero, wi-38, and nc-37 cell proliferation; the 50% inhibitory dose was 4 to 10 microm in a 4-day assay. when compared with other antiviral drugs, fiac was active at much lower concentrations than arabinosyl ... | 1980 | 6249196 |
| virus replication and localization of varicella-zoster virus antigens in human embryonic fibroblast cells infected with cell-free virus. | when human embryonic fibroblast cells were infected with cell-free varicella-zoster virus, virus replication began between 8 and 14 h postinfection, and 4 more h werp required for the virus to infect neighboring cells. virus-specific antigens were traced by the anticomplement immunofluorescent antibody technique. virus antigen was first detectable 2 h postinfection in the cytoplasma, and diffuse fluorescence was observed in the nucleus as early as 4 h after infection. the nuclear fluorescence go ... | 1980 | 6249744 |
| comparative in vitro imunotoxicology of acyclovir and other antiviral agents. | in vitro lymphocyte blastogenic responses to the commonly employed mitogens phytohemagglutinin, pokeweed, and concanavalin a were evaluated when acyclovir, adenine arabinoside, cytosine arabinoside, and idoxuridine were added to the culture materials. similarly, specific antigen-induced blastogenic responses, including herpes group antigens, and cytotoxicity and leukocyte inhibitory factor assays with herpes group viruses were determined in the presence and absence of antiviral agents. no depres ... | 1980 | 6249751 |
| varicella vaccination: where do we go from here? | although meager knowledge of the virus raises serious safety questions, the risk of death from varicella in immunocompromised children justifies further trials. in the meantime, passive immunization is a safe and relatively effective alternative. | 1980 | 6250972 |
| varicella morbidity in czechoslovakia. | data are presented on varicella and herpes zoster morbidity notified in czechoslovakia in the years 1970 to 1978. the notified varicella incidence is compared with serologically confirmed varicella incidence among the selected groups of children up to the age of 12 from the north-moravia region. comparative analysis revealed a considerable difference between the notified and serologically detected cases of varicella. the highest rate of notified varicella was recorded in children of 3 and 4 year ... | 1980 | 6251130 |
| [facial paralysis and varicella-zoster virus (vzv); fluctuations in anti-vzv antibody titers and early diagnosis by viral specific igm antibody examination (author's transl)]. | 1980 | 6251192 | |
| classics in infectious diseases. the cultivation of the poliomyelitis viruses in tissue culture by john f. enders, frederick c. robbins, and thomas h. weller. | 1980 | 6251529 | |
| isolation and polypeptide characterization of varicella-zoster virus. | 1980 | 6251617 | |
| skin test with varicella-zoster virus antigen on herpes zoster patients. | intracutaneous injection of varicella-zoster (v-z) viral antigen was performed on 55 patients with herpes zoster. all of them reacted positively after 10 days. the patients in the acute stage responded weakly wereas those in the convalescent phase developed a stronger reaction. the intensity of the reaction did not correlate with the number of days of illness. positive reactions were observed in those patients who had suffered from herpes zoster several years ago. complement fixing antibody tite ... | 1980 | 6251751 |
| viral infection and acute peripheral facial palsy. a study with herpes simplex and varicella zoster viruses. | the role of herpes simplex virus (hsv) and varicella zoster virus (vzv) in acute peripheral facial palsy (apfp) was evaluated according to clinical symptomatology and serologic findings in a series of 70 patients seen over a one-year period. peak morbidity of apfp occurred in the 21 to 30 years age group. most patients were under 40 years of age and there were more female than male patients. concomitant dysfunction of one or more other cranial nerves was present in most patients. the sera of pat ... | 1980 | 6252119 |
| solid-phase enzyme immunoassay for determination of antibodies to cytomegalovirus. | a solid-phase enzyme immunoassay for the determination of immunoglobulin h (igg) and igm antibodies to cytomegalovirus is described. the enzyme immunoassay gave reliable and consistent results which were in concordance with those obtained by the complement fixation test and the indirect immunofluorescence test. antibodies to herpes simplex and varicella-zoster viruses did not interfere in the enzyme immunoassay for cytomegalovirus igm antibodies. in a few patients with igm antibodies to epstein- ... | 1980 | 6252241 |
| [clinical aspects of chronic virus infections]. | 1980 | 6252452 | |
| in vitro susceptibility of varicella-zoster virus to acyclovir. | the in vitro susceptibility of five strains of varicella-zoster virus to acyclovir was examined by the plaque-reduction method in human diploid lung cells. the 50% effective doses of acyclovir ranged from 2.06 microm to 6.28 microm in a 7-day assay, with a mean of 3.65 microm. irreversible inhibition of plaque formtation was achieved by drug doses exceeding the 50% effective dose for plaque reduction but nontoxic to the cells. studies on the relative in vitro susceptibility of varicella-zoster v ... | 1980 | 6252836 |
| comprehensive viral immunology of multiple sclerosis. ii. analysis of serum and csf antibodies by standard serologic methods. | sera and csfs of 85 patients with multiple sclerosis (ms), 49 patients with probable ms, and 165 control patients with other neurologic diseases were assayed for antibodies to rubella, mumps, measles, parainfluenza i (strain 6/94), herpes simplex, cytomegalovirus, varicella-zoster, and vaccinia viruses. methods included complement fixation (cf), hemagglutination inhibition (hi), and complement-dependent plaque reduction (cpr). significant differences between the groups with ms and the control gr ... | 1980 | 6252874 |
| comprehensive viral immunology of multiple sclerosis. iii. analysis of csf antibodies by radioimmunoassay. | the csf from 279 patients with multiple sclerosis (ms), probable ms, or controls was examined by radioimmunoassay (ria) for antibodies to measles, rubella, mumps, parainfluenza 1 (sendai) (strain 6/94), herpes simplex (hsv), varicella, and vaccinia viruses. significantly more patients with ms than noninflammatory control patients had antibody to measles, rubella and varicella viruses, of which antibody to measles was the most prevalent. the percentage of patients with ms with two or more csf ant ... | 1980 | 6252875 |
| herpes zoster in a husband and wife. | the wife of a 75-year-old man with zoster began to suffer from this disease some 24 days after is appeared in her husband. although zoster is generally regarded to be an endogenously noncommunicable disease, the case reported herein suggests that the infection was exogenously communicated. the literature pointing up that zoster may possibly be acquired exogenously, particularly in immunosuppressed patients, is extensively reviewed. | 1980 | 6253406 |
| cryopreservation of virus-infected cells for use in the fluorescent antibody to membrane antigen test. | tissue culture cells infected with varicella-zoster, respiratory syncytial, para-influenza types 1, 2, and 3, and influenza a/texas/1/77 and a/ussr/90/77 viruses were exposed to ultraviolet light and frozen in the presence of a final concentration of 20% glycerol. these cells were quick thawed at 37 degrees c and compared with freshly prepared, living infected tissue culture cells in assays of fluorescence antibodies to membrane antigens of the infecting agents in serum, nasal wash secretions, c ... | 1980 | 6253517 |
| [viral neuraxitis. further studies of the current epidemiological and clinical aspects]. | an epidemiological and clinical investigation upon ten cases of acute viral neuraxitis observed in the country of alessandria between january 1978 - january 1979, is reported. four cases of neuraxitis were due to coxsackie b4 virus, two to coxsackie b3, two to influenza type a and one to influenza type b virus, one to rubella and one to varicella-zooster virus. in all the cases blood chemistry, clinical and instrumental examinations (eegraphy, cerebral scintigraphy and angiography) were coupled ... | 1980 | 6253851 |
| [radioprotective effectiveness of the paramunity inducer "pind-avi": investigation using the model "protective tetanic vaccination in mice" after exposure to x-rays (author's transl)]. | the model "protective tetanic vaccination in mice" was used in order to try whether the paramunity inducer pind-avi may diminish or suspend radiation-induced immunosuppression. the radioprotective effect was ascertained from the different results of immunization in mice exposed to radiation after pretreatment with either pind-avi or placebo. the dose delivered amounted to 300 r. tetanus toxoid was used for immunization. effectiveness of the tetanic vaccination was analysed by means of load tests ... | 1980 | 6254210 |
| an outbreak of varicella-zoster virus infection among cancer patients. | an outbreak of varicella-zoster infection occurred among patients of the medicine branch, national cancer institute, national institutes of health. epidemiologic investigation suggested that the outbreak was due to two distinct types of disease. one type was acquired without previous exposure to other diseased patients and invariably associated with dermatomal lesions. the other, an a typical form, was associated with person-to-person transmission and equivocal initial dermatomal distribution an ... | 1980 | 6254415 |
| viral and bacterial antibody responses in multiple sclerosis. | an imprint electroimmunofixation method (ieif) was used to characterize antibodies to eight viral antigens (measles, mumps, rubella, herpes simplex type 1, varicella-zoster, vaccinia, cytomegalovirus, adenovirus) and four bacterial antigens (beta-hemolytic streptococcus, hemophilus influenzae type b, escherichia coli, enterococcus) in serum and cerebrospinal fluid (csf) of 12 patients with multiple sclerosis (ms). twelve patients matched for age and sex sex served as controls. evidence for intra ... | 1980 | 6254433 |
| immune response of guinea pigs to varicella vaccine strain (oka) and wild strains. | an immune response (neutralizing and complement fixing antibodies) was detected in guinea pigs to varicella vaccine strain (oka), but not to 2 wild strains. the possible use of guinea pigs and the vaccine strain (oka) as a model system is discussed. | 1980 | 6254499 |
| the age distribution of neutralizing antibodies against varicella-zoster virus in healthy individuals. | a seroepidemiological survey of varicella was made in the nagoya area by the neutralization (nt) test. of 1,473 recorded cases of varicella, 81.4% were under 6 years old and 9.6% were under one year old; of the 168 recorded cases under one year old, about 30% were under 5 months old. examination of 11 pairs of mother and cord sera and 13 pairs of mother and infant sera showed that transfer of nt antibody was in general good, even in babies that were small for their age or smnall at birth after 2 ... | 1980 | 6254500 |
| experimental infection of guinea pigs with varicella-zoster virus. | weanling guinea pigs are susceptible to infection with varicella-zoster virus (vzv). animals inoculated intranasally or subcutaneously with vzv grown in fetal guinea pig tissue culture shed virus from the nasopharynx and seroconverted to vzv. viremia occurred in some animals. animal-to-animal transmission of vzv was observed. infection of weanling guinea pigs with vzv should allow assessment of the pathophysiology of viral infection in immunocompetent and specifically immunologically modified an ... | 1980 | 6255038 |
| primary epstein-barr virus infection in association with reye syndrome. | 1980 | 6255120 | |
| impact of hodgkin's disease upon the immune system. | 1980 | 6255607 | |
| rapid random-donor screening for the selection of viral antibody-containing blood donations. | we describe a 3 1/2 year trial in which we used immunofluorescence to detect and titrate antibody to six common viruses in normal healthy blood donors drawn at random from west and south east scotland. the trial was designed to allow selection of blood donations rich in specific antiviral antibody for inclusion in the plasma pool which would, in turn, be used for the preparation of specific antiviral immunoglobulin. the results show the natural frequency of occurrence of antibody to different vi ... | 1980 | 6255854 |
| [herpes simplex and herpes varicella-zoster. cytological and ultrastructural study]. | nuclear staining qualities, and cell morphology depart from normal when epithelial cells are infected by herpes virus hominis and herpes varicella-zoster (1). the cytopathic changes produced by both viruses are similar and constant enough to be considered characteristic of the infection. since the skin vesicles are readily accessible for examination, it is easy to scrape infected cells from the floor of the exposed blister and establish the diagnosis. the simplest and most common method would be ... | 1980 | 6168875 |
| new developments with new vaccines. | 1980 | 6259664 | |
| [clinico-pathogenetic variants of peripheral nervous system diseases of herpetic etiology]. | of 340 patients with various manifestations of herpetic disease, 261 showed predominant involvement of the peripheral nervous system. apart from ganglioneuritis of the cranial and spinal nerves there occurred forms accompanied by inflammatory changes in the liquor, commissural processes in the meninges, involvement of the anterior roots and vegetative ganglions. the results of clinicovirological comparisons and differentiation of herpetic diseases as well as their initial manifestations are repo ... | 1980 | 6259855 |
| detection of human cytomegalovirus-specific igg antibodies by a sensitive solid-phase radioimmunoassay and by a rapid-screening test. | a radioimmunoassay (ria) for the detection of human igg antibodies to cytomegalovirus (cmv) which utilizes extracts of cmv-infected cells as antigen is described. sera of 66 healthy adults were titered by the ria and by the complement fixation (cf) test. these same subjects were also used in the evaluation of a rapid screening radioimmunoassay (rsria) developed to detect igg antibodies to cmv in small serum samples. the specificity of the ria was evaluated by testing sera of seven cmv patients a ... | 1980 | 6262448 |
| anti-herpes simplex virus and anti-human cell growth activity of e-5-propenyl-2'-deoxyuridine and the concept of selective protection in antivirus chemotherapy. | e-5-propenyl-2'-deoxyuridine (e-5-propenyl-durd) inhibited the growth of herpes simplex virus (hsv) types 1 (hsv-1) and 2 in culture. the concentration of drug required to give a 2-log reduction in virus titer was 5 microm for hsv-1 and 23 microm for hsv-2. the anti-hsv-1 activity of this agent was more potent than 5-propyl-durd, equivalent to e-5(3,3,3-trifluoropropenyl)-durd, and less potent than e-5-bromovinyl-durd. the hsv-1 mutant (b2006) lacking the ability to induce virus-specific thymidi ... | 1980 | 6263181 |
| [varicella-zoster virus infection in children with leukemia]. | 1980 | 6261111 | |
| immunoglobulins m and g to varicella-zoster virus measured by solid-phase radioimmunoassay: antibody responses to varicella and herpes zoster infections. | both immunoglobulin m (igm) and igg antibodies to varicella-zoster virus (vzv) were detectable in a solid-phase radioimmunoassay with 125i-labeled goat antisera to human immunoglobulins. primary infection with vzv was associated with early production of igm and igg antibodies and rapid development of lymphocyte transformation to vzv antigen. among eight subjects with varicella tested 1 to 4 days after onset, seven patients had igg and six patients had igm antibodies; all patients had both igg an ... | 1980 | 6260833 |
| varicella-zoster antibodies in patients with hodgkin's disease. | statistically significant differences in mean varicella-zoster antibody titre was found between the normal population and hodgkin's disease group. no difference in mean antibody titre between the four histological categories of the disease was found. | 1980 | 6265816 |
| screening blood donors for high titre antibody to herpes varicella-zoster. | as a method of increasing supplies of varicella-zoster immunoglobulin, semi-automated screening of blood donors for high titre complement-fixing antibody was initiated. this was compared with the previously used method of donor selection based on a history of varicella or zoster in the past 6 months. about one-third of the "history" donors had titres of greater than or equal to 1 in 64 and generally these levels declined rapidly. in contrast, although only 1.1% of donors in random screening had ... | 1980 | 6267817 |
| direct immunofluorescence staining for detection of herpes simplex and varicella-zoster virus antigens in vesicular lesions and certain tissue specimens. | direct immunofluorescence (if) staining was compared with virus isolation for detection of herpes simplex viruses (hsv) and varicella-zoster virus (vzv) directly in clinical materials. these included 199 vesicular lesion specimens and 280 tissue specimens. correspondence between if and isolation results was 88% in testing for hsv in lesion specimens and 98% in testing for hsv in various tissue (mostly brain) specimens. overall, if was positive for 82% of the specimens in which hsv was demonstrat ... | 1980 | 6268653 |
| varicella-zoster virus in the human corneal endothelium: a case report. | 1980 | 6269677 | |
| varicella-zoster-associated encephalitis: detection of specific antibody in cerebrospinal fluid. | varicella-zoster (vz) antibody measured by indirect immunofluorescence was used to identify patients with encephalitis due to vz virus. in 15 of 16 (94%) patients with vz infection and clinical evidence of central nervous system involvement, vz antibody was present at a titer of 1:2 or greater in cerebrospinal fluid. in contrast, no vz antibody was detected in the cerebrospinal fluid of seven patients with vz infections without clinical signs of central nervous system involvement, nor was any de ... | 1980 | 6273449 |
| [an inhibitor of the replication of varicella-zoster virus]. | 1980 | 6281113 | |
| infections in leukemic children: a prospective analysis. | a 28-month prospective study of 54 leukemic children was carried out to determine the incidence and type of infection associated with febrile episodes. fever was caused by infections in 84 of 199 episodes (71%). two-thirds of the febrile episodes and 57% of the documented infections occurred when leukemic activity was demonstrable. however, only nine of 29 febrile episodes which occurred at the time of initial diagnosis of acute leukemia were due to infection. all serious bacterial infections oc ... | 1980 | 6988557 |
| rapid diagnosis of varicella-zoster virus infection by direct immunofluorescence. | laboratory results were reviewed for 47 patients who had skin lesions that had been simultaneously examined by viral culture and direct immunofluorescence for the presence of varicella-zoster virus. immunofluorescence established the diagnosis in 24 of 28 patients (86%) strongly suspected on clinical grounds of having varicella-zoster infection. viral culture was positive in only 10 of 28 patients (36%). skin lesions in 19 patients who had other diagnoses were negative by both tests. direct immu ... | 1980 | 6990743 |