| properties of mouse embryo fibroblasts transformed in vitro by infectious bovine rhinotracheitis virus. | infection of cd-1 mouse embryo fibroblast(s) (mef) with infectious bovine rhinotracheitis virus (ibrv) strain hmc resulted in persistent infection and subsequent transformation of these cells. ibrv-transformed mef cultures consisted of short fibroblastoid cells, and ibrv-specific membrane and intracellular antigens were detectable in early in vitro passages by indirect imunofluorescence (if) techniques. the presence of ibrv genetic information was confirmed in if-positive and if-negative cells b ... | 1980 | 6249951 |
| diagnosis of rotavirus, adenovirus, and herpesvirus infections by immune electron microscopy using a serum-in-agar diffusion method. | the sensitivity of immune electron microscopy (iem) for the detection and identification of bovine rotavirus, infectious bovine rhinotracheitis virus (ibr), and canine adenovirus has been studied by using the serum-in-agar (sia) method in which a specific antiserum has been incorporated in agar. | 1980 | 6250692 |
| infectious bovine rhinotracheitis vaccine. | | 1980 | 6251596 |
| [vaccination of cattle against respiratory disease caused by virus infection (author's transl)]. | studies on the epizootiology of respiratory viruses in herds of cattle showed that infection by bovine respiratory syncytial (brs) virus was a major cause of bovine respiratory disease in calves. moreover, of ibr virus infection associated with respiratory symptoms were observed in the netherlands since the spring of 1974. outbreaks of ibr virus infections occur throughout the netherlands today. initially, outbreaks ran a course marked by the typical symptoms of haemorhagic rhinitis, observed pa ... | 1980 | 6252650 |
| transmission of a genital isolate of bovine herpesvirus 1 to calves by the respiratory route. | | 1980 | 6252885 |
| rapid onset of immunity in cattle after intramuscular injection of a modified-live-virus ibr vaccine. | | 1980 | 6254226 |
| chemotherapeutic value of 2-deoxy-d-glucose in infectious bovine rhinotracheitis viral infection in calves. | daily injection of 2-deoxy-d-glucose (2-dg) had no protective effect against respiratory tract infection in calves caused by infectious bovine rhinotracheitis virus. it also did not reduce the severity of this infection. ocular instillation of the drug, however, markedly reduced the severity of viral-induced conjunctivitis and keratoconjunctivitis. the drug was effective when given at the time of ocular infection or after clinical conjunctivitis developed. | 1980 | 6254407 |
| use of a modified live infectious bovine rhinotracheitis vaccine in the field. | | 1980 | 6255665 |
| a micro-enzyme-linked immunosorbent assay for the detection of antibodies to infectious bovine rhinotracheitis virus. | | 1980 | 6255670 |
| [main respiratory virus and chlamydia psittaci antibody survey by passive hemagglutination on bovine serum from togo]. | | 1980 | 6256826 |
| the prevalence of serum neutralizing antibodies to infectious bovine rhinotracheitis virus in scotland. | the prevalence of serum neutralizing antibodies to infectious bovine rhinotracheitis virus in 1152 serum samples from adult cattle in 114 dairy and beef herds in different regions of scotland was 12%. in the grampian region, the number of seropositive cattle in the self-contained herds was significantly less (p less than 0.01) than in the "other" herds. holstein cattle had been introduced into five of these "other" herds, and significantly more (p less than 0.01) of the samples from these five h ... | 1981 | 6257782 |
| [detection of ibr/ipv antibodies in milk]. | | 1980 | 6258223 |
| infectious bovine rhinotracheitis virus excretion after vaccination. | | 1980 | 6258285 |
| attempts to reactivate bovid herpesvirus-2 in experimentally infected calves. | a study was carried out to determine whether bovid herpesvirus-2 (bhv-2) is able to induce a recurrent infection in experimentally infected calves. twelve calves infected with the virus were treated with dexamethasone (dms) beginning 69 days after the infection, ie, several weeks after the animals had recovered from the disease and were negative for bhv-2. the stress induced by dms treatment failed to reactivate the clinical condition or to induce shedding of bhv-2. however, treatment with dms r ... | 1980 | 6259974 |
| neural changes in vaccinated calves challenge exposed with virulent infectious bovine rhinotracheitis virus. | recurrent infection in calves vaccinated with infectious bovine rhinotracheitis-(ibr) modified live virus was induced by dexamethasone (dm) treatment given 49 days after challenge exposure with virulent ibr virus. nonchallenge-exposed im and intranasally vaccinated calves did not excrete the virus after dm treatment; however, im and intranasally vaccinated and subsequently challenge-exposed calves excreted the challenge-exposure virus into the nasal secretions 5 to 11 days and 6 to 10 days after ... | 1980 | 6259976 |
| reactivation of temperature-sensitive and non-temperature-sensitive infectious bovine rhinotracheitis vaccine virus with dexamethasone. | latent infections by a temperature-sensitive (ts) infectious bovine rhinotracheitis virus vaccines was produced as frequently as by non-ts vaccine virus. thus virus could be reactivated in seven of eight ts vaccinates and six of eight non-ts vaccinates after dexamethasone treatment. virus excretion could be detectable for 1 to 8 days at a level of 2 x 10(6) to 3 x 10(8) plaque-forming units per ml of nasal secretions. the reactivated virus was shown to be the same as the original virus used for ... | 1980 | 6260654 |
| [antigen isolation and the applicability of a microvariant of the complement fixation reaction in infectious bovine rhinotracheitis]. | comparative investigations were carried out on 3 ibr cellular cultural antigens with regard to the cf-micromethod, produced by different methods. the best qualities with regard to sensitivity and specificity were reached by the antigen concentrated by ultracentrifuging. high coincidence rate was observed in discovering ibr antibodies in the blood serums of cows through the cf and vnr tests--96% of the positive and negative results although the cf reaction showed lower sensitivity. a conclusion w ... | 1980 | 6261439 |
| protection of cattle vaccinated with inactivated oil-adjuvant ibr-vaccine against experimental infection. | | 1980 | 6261487 |
| [specificity of the resistance exhibited by peritoneal macrophages of rats immunized against rubeola virus]. | peritoneal macrophages in rats with no immunization against rubella virus and inoculted with bovine infectious rhinotracheitis virus are prone to suffer from a cytopathogenic effect with formation of inclusion bodies, and lysis, succeeding in reisolating the virus. the resistance of peritoneal macrophages of rats inoculated against rubella virus in nonspecific, since such resistance continues to show when macrophages interact with bovine infectious rhinotracheitis virus. the results support evid ... | 1980 | 6264551 |
| disease outbreak in calves caused by a mixed infection with infectious bovine rhinotracheitis virus and bovine virus diarrhoea virus. | | 1981 | 6266121 |
| bovine abortion associated with infectious bovine rhinotracheitis virus infection. | | 1981 | 6266124 |
| induction of persistent infection in mice and oncogenic transformation of mouse macrophages with infectious bovine rhinotracheitis virus. | infectious bovine rhinotracheitis virus (ibrv) established long-term persistent infection in intracerebrally inoculated athymic nude mice. after intraperitoneal injection into outbred mice, virus was isolated for only 3 days from spleens and livers. in vitro inoculation of outbred mouse spleen fragments with ibrv resulted in persistent infection and subsequent transformation of spleen macrophages. the ibrv-specific membrane and intracellular antigens were detected by indirect immunofluorescence ... | 1981 | 6266290 |
| bovine herpesvirus type 1 in the sperm of a bull from a herd with fertility problems. | a herd of 125 holstein cows manifested fertility problems for two years. the number of services per pregnancy was 2.97, conception rate was 33% after the first service, and the average number of open days was 127. abortions occurred in four cows over the last 12 months. the herd was not vaccinated against any disease. natural service by a bull and artificial insemination were used for breeding the cows. bovine herpesvirus type 1 was demonstrated in sperm heads from the bull by direct and indirec ... | 1980 | 6266630 |
| ibr virus excretion after vaccination. | | 1981 | 6267765 |
| recrudescence of infectious bovine rhinotracheitis virus and associated neural changes in calves treated with dexamethasone. | reactivation of infection bovine rhinotracheitis (ibr) virus in calves administered dexamethasone (dm) was studied in 2 experiments. at 2, 3, 5, 15, or 30 months after inoculation of the los angeles strain of ibr virus, iv injections of dm were given for 5 consecutive days to induce a recurrent infection (experiment 1). three months after the 1st treatment, a 2nd recurrent infection was induced, using dm with the same doses as used in experiment 1. the virus was excreted from nasal secretions fr ... | 1981 | 6267968 |
| comparison of the effect of trisodium phosphonoformate on the mean plaque size of pseudorabies virus, infectious bovine rhinotracheitis virus and pigeon herpesvirus. | | 1980 | 6268670 |
| [virus neutralizing antibody levels following acute ibr]. | | 1981 | 6272387 |
| eye disease in ibr. | | 1981 | 6272469 |
| serologic survey for selected microbial agents in mammals from alberta, 1976. | blood samples were taken from humans and several species of free-ranging wild mammals from five different geographic areas of alberta, canada. sera were tested for antibody to eastern equine encephalitis (eee) virus, western equine encephalitis (wee) virus, st. louis encephalitis (sle) virus, powassan (pow) virus, the snowshoe hare (ssh) strain of the california group (cal) of viruses, northway (nor) virus, klamath (kla) virus, infectious bovine rhinotracheitis (ibr) virus, and two bacteria, bru ... | 1981 | 6273600 |
| [suitability of ferrets for the ibr-ipv vaccine efficacy evaluation]. | | 1981 | 6274304 |
| persistent infection with bovine herpesvirus type 1: rabbit model. | persistent infection with bovine herpesvirus type 1 (bhv-1) was established in all rabbits after conjunctival inoculation of virus. spontaneous reactivations of bhv-1 with and without the appearance of recurrent ocular lesions were observed in persistently infected rabbits. bhv-1 was reactivated predictably and shed from all persistently infected rabbits after the administration of dexamethasone. during all reactivations, bhv-1 isolation was restricted to the inoculated eye. | 1982 | 6274801 |
| proteins specified by bovine herpesvirus 1 (infectious bovine rhinotracheitis virus). | an electrophoretic analysis of radioactively labeled, purified, "empty" and dna-containing infectious bovine rhinotracheitis virions revealed the presence of 25 to 33 structural (virion) polypeptides. a total of 11 of these polypeptides could be labeled with [3h]glucosamine and were identified as glycoproteins. in addition to the 25 structural polypeptides, infectious bovine rhinotracheitis virus infected cells also contained at least 15 nonstructural (nonvirion) polypeptides that were not prese ... | 1981 | 6275094 |
| further studies of naturally occurring latent bovine herpesvirus infection. | attempts were made to enhance the isolation rate of latent bovine herpesviruses from trigeminal ganglia by using a fibroblastic fetal bovine kidney cell line, in addition to madin-darby bovine kidney cells, and by superinfecting with a temperature-sensitive helper strain of bovine herpesvirus-1 (bhv-1). four isolates of latent bhv-1 were obtained from 44 pairs of trigeminal ganglia--thus reflecting no increase in isolation rate over that previously observed. two isolates of a latent bovine herpe ... | 1981 | 6275750 |
| [multiplication of the ibr, pi-3 and bvd-md viruses in cell and organ cultures of bovine fetuses after experimental intrauterine infections]. | the intrauterine infection of four- to nine-month-old bovine foetuses with the pi-3, bvd-md viruses, performed 7 to 72 days prior to their delivery, did not exert any significant influence upon the susceptibility of primary cell cultures from foetal organs and tissues to further viral infection in vitro. the bvd-md and ibr viruses multiplied in the primary cell cultures from the organs of a foetus infected with the pi-3 virus seven days before delivery even in the presence of endogenous pi-3 vir ... | 1981 | 6277081 |
| the use of infectious bovine rhinotracheitis vaccine in a commercial veal unit: antibody response and spread of virus. | | 1982 | 6277422 |
| susceptibility of cell line cultures of bovine kidney origin to infectious bovine rhinotracheitis and parainfluenza-3 viruses. | | 1981 | 6277558 |
| isolation of infectious bovine rhinotracheitis virus from the soft-shelled tick, ornithodoros coriaceus. | infectious bovine rhinotracheitis virus was isolated from the soft-shelled tick (ornithodoros coriaceus). serological identification of the isolated viruses was confirmed by restriction endonuclease digestion of purified virus dna. these isolations indicate that the soft-shelled tick may be a vector for infectious bovine rhinotracheitis virus. this may be the first reported isolation of mammalian herpesvirus from an arthropod vector. | 1982 | 6278596 |
| effect of infectious bovine rhinotracheitis virus infection on bovine alveolar macrophage function. | bovine alveolar macrophages isolated in culture were assessed for immunological activity in assays for fc and complement receptors, for phagocytosis, and for effector cell function in antibody-dependent cell cytotoxicity. in the case of uninfected alveolar macrophages, fc receptors were detected on approximately 94% of macrophages and complement receptors were detected on 39%. phagocytosis of immunoglobulin g-coated sheep erythrocytes occurred in 58% of macrophages, and phagocytosis of opsonized ... | 1982 | 6279511 |
| bovid herpesvirus 2 latency: failure to recover virus from central sensory nerve ganglia. | latent bovid herpesvirus 2 was sought in sensory ganglia, epithelium and lymph nodes from cattle having antibodies against bovid herpes virus 2. tissues from eight animals were maintained in vitro as explants for 49-72 days during which all expended media was tested for virus. three animals were pretreated with corticosteroids prior to slaughter. infectious bovine rhinotracheitis virus was recovered from one animal, but bovid herpesvirus 2 was not detected. | 1982 | 6280823 |
| [possibilities and limits of md/vd and ibr vaccination in a cattle fattening stable. observations of a case in practice (author's transl)]. | | 1982 | 6280958 |
| risk factors related to the prevalence of infectious bovine keratoconjunctivitis. | a cross-sectional epizootiologic study was conducted by mailed questionnaire to determine how the prevalence of infectious bovine keratoconjunctivitis (ibk) related to selected predisposing causes. the prevalence of ibk in missouri during the summer of 1978 was 4.97 cases/100 cattle, with 45% of respondents reporting cases of ibk. a higher prevalence of ibk was associated with calves and yearlings, hereford and hereford-cross cattle, backgrounding cattle operations, and herds with a history of i ... | 1981 | 6281222 |
| [virus neutralization microreaction to determine antibodies against the infectious bovine rhinotracheitis virus]. | comparative studies were carried out with a total of 170 serum samples from cattle with the use of the virus-neutralization test and the virus-neutralization microreaction to demonstrate the presence of antibodies against the ibr virus. it was found that the two reactions were equally effective in terms of specificity. the coincidence of the results obtained with regard to the positive and negative tests was 97 per cent with variant alfa and 98 per cent with variant beta. comparatively higher se ... | 1981 | 6283727 |
| dna of bovine herpesvirus type 1 in the trigeminal ganglia of latently infected calves. | twelve calves infected with bovine herpesvirus type 1 (bhv-1) were killed when in a latent state of infection. latency was verified 30 days after virus inoculation of the calves by seroconversion, absence of virus shedding, and in 2 calves, by recrudescence of the infection after they were treated with dexamethasone. by in situ hybridization techniques and autoradiography, dna of bhv-1 was detected in 13 of 23 trigeminal ganglia of latently infected calves. viral dna was restricted to the nucleu ... | 1982 | 6283952 |
| vaccination of cattle against pseudorabies (aujeszky's disease) with homologous virus (herpes suis) and heterologous virus (herpes bovis 1). | study was made to determine whether vaccination of cattle against pseudorabies (pr; aujeszky's disease) affords protection upon subsequent intranasal challenge exposure with virulent virus. vaccinations were performed with a commercially available oil-adjuvant pr virus vaccine, in some cases supplemented with a1(oh)3 (given subcutaneously), with the attenuated nia4 strain of pr virus (given intranasally), and with a commercially available temperature-sensitive mutant of bovine herpesvirus-1 (inf ... | 1982 | 6283963 |
| natural cell-mediated cytotoxicity of bovine mononuclear cells against virus-infected cells. | the ability of mononuclear cells (mc) from peripheral blood of normal cattle to lyse a variety of cells was tested in a 51cr-release microcytotoxicity assay. several types of bovine cells infected with parainfluenza 3 virus (pi3v) were susceptible to natural cytotoxicity. bovine cells infected with infectious bovine rhinotracheitis virus or noncytopathogenic bovine viral diarrhea virus, uninfected bovine cells, and human cell lines molt-3, hsb-2, k562, and u-937 were not susceptible. the period ... | 1982 | 6284642 |
| prevalence of antibodies of selected infectious disease agents in the peninsular desert bighorn sheep (ovis canadensis cremnobates) of the santa rosa mountains, california. | | 1982 | 6285010 |
| [characterization of bovine herpesvirus type i puente alto chile 1977 strain]. | | 1981 | 6285438 |
| [detection of ibr/ipv antibodies in milk]. | | 1982 | 6285456 |
| virologic study of the reproductive tract in dairy cows. | from aug 1, 1979 to aug 15, 1980, a total of 624 samples were collected from the vaginas, cervices, and uteri of 208 dairy cows 30 to 37 days after parturition. an additional 90 samples were collected from the reproductive tracts from 30 of the 208 cows. the 30 cows had aborted or were repeat breeders. samples from cows that had aborted were collected within a week after clinical abortion or immediately after rectal palpation revealed subclinical abortion. all samples were tested for the presenc ... | 1982 | 6285771 |
| effect of levamisole in immune responses to bovine herpesvirus-1. | the effect of levamisole on bovine immune responses to infectious bovine rhinotracheitis virus was assessed under laboratory and commercial feedlot situations. in all instances, levamisole appeared to have a beneficial effect on antibody responses of the cattle after vaccination. in the smaller scale pilot trials, levamisole appeared to be more efficacious when given 7 days after vaccination, presumably when a large amount of viral antigens was present as a result of viral replication. in the la ... | 1982 | 6285779 |
| association between route of inoculation with infectious bovine rhinotracheitis virus and site of recrudescence after dexamethasone treatment. | four calves latently infected with infectious bovine rhinotracheitis virus (ibrv) were used to compare the ease of isolation of virus from neuronal ganglia and from mucosal surfaces. two calves were slaughtered, and neuronal ganglia (cranial cervical, trigeminal, and 3rd and 4th sacral) were cocultivated on bovine fetal kidney cells. virus was not isolated. two calves given dexamethasone for 4 days were slaughtered on the 5th day. virus was not isolated from cocultivated or macerated neuronal ga ... | 1982 | 6285780 |
| prevalence of bovine herpesvirus-1, bovine oral diarrhea, parainfluenza-3, bovine adenoviruses-3 and -7, and goat respiratory syncytial viral antibodies in goats. | sera from healthy goats were collected during october 1979 through october 1980. these sera were tested for bovine herpesvirus-1 (bhv-1), bovine viral diarrhea virus (bvdv), parainfluenza-3 (pi-3) virus, bovine adenoviruses (bav) -3 and -7, and goat respiratory syncytial virus (grsv) antibodies by microtitration virus-neutralization test. the number of herds with seropositive goats for each virus were: 5/38 (13.2%) for bhv-1; 9/38 (23.7%) for bvdv; 8/38 (21.1%) for pi-3 virus; 1/38 (2.6%) for ba ... | 1982 | 6285781 |
| safety and efficacy of live and inactivated infectious bovine rhinotracheitis vaccines. | two commercial live virus infectious bovine rhinotracheitis (ibr) vaccines for intranasal administration and an inactivated polyvalent calf pneumonia vaccine were compared for safety and efficacy in calves against experimental ibr infections. all three products were clinically safe for use in young calves; a mild, transient, febrile response was induced by one of the live vaccines. vaccinal virus was recovered for up to 16 days after vaccination from nasal secretions of all calves given live vac ... | 1982 | 6289508 |
| [infection eradication studies based on infectious bovine rhinotracheitis/infectious pustulous vulvovaginitis virus. 1. modification of virus latency following natural ibr/ipv infection by subsequent immunization with riems live ibr/ipv vaccine]. | | 1981 | 6289768 |
| a review of infectious bovine rhinotracheitis, shipping fever pneumonia and viral-bacterial synergism in respiratory disease of cattle. | unanswered questions on the etiology and prevention of shipping fever pneumonia have allowed this disease to remain one of the most costly to the north american cattle industry. research in this area has indirected that while pasteurella haemolytica and, to a lesser extent, p. multocida are involved in most cases, they seem to require additional factors to help initiate the disease process. bovine herpes virus 1 has been shown experimentally to be one such factor. this review examines in some de ... | 1982 | 6290011 |
| immune responses of dairy cattle to parainfluenza-3 virus in intranasal infectious bovine rhinotracheitis-parainfluenza-3 virus vaccines. | two hundred and fifty dairy heifers were vaccinated at three to six months of age with an intranasal infectious bovine rhinotracheitis-parainfluenza-3 vaccine. eighteen additional heifers were tested prior to vaccination and again three to four weeks after vaccination. neither cell-mediated nor humoral immunity was significantly raised to parainfluenza-3 virus in either group of cattle. | 1982 | 6290012 |
| aerosol vaccination of calves with pasteurella haemolytica against experimental respiratory disease. | three experiments were conducted on calves in which the efficacy of vaccination with live pasteurella haemolytica in aerosol was tested by challenge with sequential aerosol exposure to bovine herpesvirus 1 and p. haemolytica. neither single nor multiple aerosol vaccinations protected against the experimental disease. macroscopically recognizable rhinitis, tonsillitis, tracheitis and pneumonia occurred in both controls and vaccinates. in one experiment as many as three aerosol vaccinations with l ... | 1982 | 6290014 |
| effect of infectious bovine rhinotracheitis virus immunization on viral shedding in challenge-exposed calves treated with dexamethasone. | calves not vaccinated with infectious bovine rhinotracheitis virus (ibrv) became latently infected when challenge exposed and treated with dexamethasone (dm). calves that shed ibrv after dm treatment were considered to be latently infected. vaccination with a temperature-sensitive intranasal vaccine or with formalinized ibrv in freund's complete adjuvant (ibrv-fca) protected some, but not all, calves against latent infection--indicating a role for the immune response in preventing latent infecti ... | 1982 | 6293350 |
| respiratory tract immune response to microbial pathogens. | effective resistance to respiratory tract infection depends principally on specific immunity on mucosal surfaces of the upper or lower respiratory tract. respiratory tract immune response comprises antibody and cell-mediated systems and may be induced most readily by surface presentation of replicating agents but can result from parenteral or local presentation of highly immunogenic antigens. upper and lower respiratory tract systems differ in immunologic competence, with the lungs having a grea ... | 1982 | 6294027 |
| theory and practice of immunoprophylaxis in cattle. | | 1982 | 6294031 |
| [infectious bovine rhinotracheitis--infectious pustular vulvovaginitis (ibr/ipv)]. | | 1982 | 6294906 |
| importance of competitive binding in the detection of antigen specific bovine isotypes and subisotypes by the micro elisa. | an enzyme-linked immunosorbent assay was developed to detect and quantify the specific bovine immunoglobulin class response to trypanosoma theileri, dictyocaulus viviparus and infectious bovine rhinotracheitis virus. comparative measurement of the specific immunoglobulin classes in whole serum was achieved using monospecific rabbit antibovine igg1, igg2 and igm, followed by a goat anti-rabbit ig-enzyme conjugate (antiglobulin elisa). the results obtained in the antiglobulin elisa compared favour ... | 1982 | 6296953 |
| experimental latent and recrudescent bovine herpesvirus-1 infections in calves. | latent bovine herpesvirus-1 (bhv-1) infection was established in 6 calves and was demonstrated by reinduction of virus shedding after administration of corticosteroids. latently infected calves failed to transmit bhv-1 during 4 weeks' contact with sentinel calves. infected calves were killed and necropsied during latency or induced recrudescence. the bhv-1 dna was demonstrated intranuclearly in trigeminal ganglion neurons by in situ hybridization. the bhv-1 antigen was demonstrated by immunofluo ... | 1983 | 6299146 |
| detection of infectious bovine rhinotracheitis and bovine viral diarrhea viruses in the nasal epithelial cells by the direct immunofluorescence technique. | nasal epithelial cells were collected by cotton swabs for the diagnosis in experimental and field cases of infectious bovine rhinotracheitis and field cases of bovine viral diarrhea in calves. a portion of the cells was washed twice in phosphate buffered saline and a 25 microl drop was placed on microscope slides. the cells were dried, fixed and stained according to the direct fluorescent antibody technique. another portion of the same specimen was inoculated onto primary bovine skin cell cultur ... | 1983 | 6299484 |
| effect of viral dose on experimental pneumonia caused by aerosol exposure of calves to bovine herpesvirus 1 and pasteurella haemolytica. | the effect of various aerosol doses of bovine herpesvirus 1, followed four days later by aerosol exposure to a constant level of pasteurella haemolytica, was studied in 16 crossbred hereford range calves. a collision nebulizer was used to generate aerosols from virus suspensions with concentrations of 10(8.2) (high), 10(5.2) (moderate) or 10(2.2) (low) tcid50/ml. the bacterial suspension contained 10(7) colony forming units/ml. control calves exposed only to p. haemolytica developed no pulmonary ... | 1983 | 6299485 |
| rapid detection of antibodies to infectious bovine rhinotracheitis by 'macro' and 'micro' elisa. | two kinds of enzyme-linked immunosorbent assay were evaluated in their ability to detect specific antibodies against bovine rhinotracheitis virus (ibr-ipv). the tests were called macroelisa and microelisa, according to the kind of the solid support used for antigen insolubilization, polystyrene beads and microtitration plates respectively. partially purified virus was used to coat both beads and plates; a single dilution of examples was tested and protein a linked to peroxidase was employed as e ... | 1982 | 6299826 |
| [elisa of ibr (infectious bovine rhinotracheitis)--an expression of a 50 percent elisa titer]. | | 1982 | 6299827 |
| [vaccines and vaccination against infectious bovine rhinotracheitis]. | | 1982 | 6299852 |
| [problems in the latency period following vaccination against infectious bovine rhinotracheitis virus (bovid herpesvirus 1)]. | | 1982 | 6299855 |
| infectious bovine rhinotracheitis: study on the experimentally induced disease and its prevention using an inactivated, adjuvanted vaccine. | experimentally induced ibr was studied in calves. intranasal challenge enabled reproducible results to be obtained, both from qualitative (clinical aspect) and quantitative points of view (virus excretion, temperature); local and general immunity were also evaluated. this challenge method is useful when studying ibr vaccines. the disease was also experimentally induced by putting healthy animals into contact with diffusor calves. a single injection of inactivated vaccine in oily adjuvant already ... | 1982 | 6299856 |
| experimental infectious bovine rhinotracheitis: comparison of four antigen detection methods. | the duration of detectable viral antigen in nasal secretions was studied by four methods in calves experimentally infected with infectious bovine rhinotracheitis. virus isolation in cell culture was the most sensitive and was successful for up to 11 days after inoculation. three direct rapid antigen detection systems (immunofluorescence, immunoperoxidase and enzyme-linked immunosorbent assay [elisa]) were all successful during the pyrexic phase, but less useful in the later stages of the disease ... | 1983 | 6300979 |
| neutralizing antibodies to bovine herpesvirus 1 in reindeer. | | 1982 | 6301239 |
| histological changes in the respiratory tract of calves exposed to aerosols of bovine herpesvirus 1 and pasteurella haemolytica. | histopathological changes in the respiratory tract of 19 calves exposed sequentially to aerosols of bovine herpesvirus 1 (infectious bovine rhinotracheitis virus) and pasteurella haemolytica, either 4 or 5 days apart, are described. tissues were examined 1.5 to 14 days following the bacterial aerosol. the salient features were hyperaemia of pharyngeal tonsils and lamina propria of air passages and alveoli; alveolitis associated with oedema and fibrin in lumen and septa; pneumocytes, mononuclear ... | 1983 | 6302139 |
| preliminary survey for antibodies against five bovine viruses in cattle in korea. | | 1982 | 6302359 |
| evaluation of an immunofluorescent test for the rapid diagnosis of field infections of infectious bovine rhinotracheitis. | an indirect immunofluorescent test for the rapid detection of infectious bovine rhinotracheitis (ibr) virus in smears of nasal and ocular secretions from infected cattle, was compared with conventional virus isolation procedures using 200 swabs from 107 field outbreaks of suspected ibr. virus was isolated from 38 per cent of the swabs and the indirect immunofluorescent test detected virus in 14.5 per cent of the positive swabs. examination of samples from more than one animal increased the confi ... | 1983 | 6302972 |
| isolation of infectious bovine rhinotracheitis virus from buffalo in malaysia. | | 1983 | 6302973 |
| identification of envelope and nucleocapsid proteins of infectious bovine rhinotracheitis virus by sds-polyacrylamide gel electrophoresis. | infectious bovine rhinotracheitis (ibr) virus was purified by rate zonal and isopycnic centrifugation in potassium tartrate gradients. viral nucleocapsids were isolated from purified virions by treatment with the nonionic detergent triton x-100 followed by high speed centrifugation. this treatment was shown to produce a suspension of 74% completely de-enveloped nucleocapsids, 24% incompletely de-enveloped nucleocapsids, and 2% whole virions. the viral nucleocapsids contained dna and banded at a ... | 1983 | 6302976 |
| bovid herpesvirus 1 infection of cattle: pathogenesis, latency, consequences of latency. | | 1982 | 6303191 |
| non-specific antiviral activity of bovine leukocytes against infectious bovine rhinotracheitis virus in vitro. | leukocytes collected from bovine blood inhibit the multiplication of virus in ibr infected mdbk cells. this inhibition is non-specific and can be observed in the absence of serum. number of infected cells, number of leukocytes per infected cell and time of placing of leukocytes onto infected cells are some of the important factors in this protection. we observed variations between animals, but for each animal the activity of leukocytes was constant for several months. contact between leukocytes ... | 1982 | 6303192 |
| persistence of antibodies and anamnestic response in calves vaccinated with inactivated infectious bovine rhinotracheitis virus and parainfluenza-3 virus vaccines. | persistence of antibodies in calves vaccinated with 2 types of inactivated infectious bovine rhinotracheitis (ibr) virus and parainfluenza-3 (pi-3) virus vaccines were determined. calves seronegative for ibr and pi-3 viruses were inoculated with 2 doses of inactivated ibr virus-pi-3 virus vaccines administered 2 weeks apart. blood samples were obtained from the calves for serum at 2 weeks, 6 months, and 1 year after vaccination. the serums were tested by serum-neutralization tests. antibody resp ... | 1983 | 6303996 |
| [timing of sensitization and appearance of skin allergic reaction in infectious bovine rhinotracheitis--infectious pustular vulvovaginitis]. | allergic and serologic investigations were carried out on infectious bovine rhinotracheitis--infectious pustular vulvovaginitis with cattle artificially and spontaneously affected with the causative agent of the disease as well as with cattle that were treated with a live attenuated vaccine. it was found that in the case of experimental infection the allergization of the body and the positive skin allergic reaction set in as early as the 7th day of the disease while in the case of vaccination th ... | 1982 | 6304991 |
| experimental infection of cattle of different ages with infectious bovine rhinotracheitis virus (strichen strain). | the clinical signs and pathological lesions which developed in various ages of cattle experimentally infected intranasally with the "strichen" strain of ibr virus were similar to, but generally milder than, those of the field disease. the clinical signs were most severe 4 days after infection and had almost wholly regressed after 12 days. serum neutralizing antibodies were detected in every animal. virus was isolated from nasal and ocular swabs for up to 13 days and 10 days, respectively, after ... | 1983 | 6306070 |
| reactivation and shedding of bovine herpesvirus 1 following dictyocaulus viviparus infection. | three groups of 4 bullocks which had recovered from infectious bovine rhinotracheitis (ibr) were infected 5 months later with dictyocaulus viviparus larvae. bovine herpesvirus 1 was recovered from days 7 to 21 post-infection from the nasal secretions of the group given 50 larvae per kilogram and on one occasion from those given 1000 larvae per animal (less than 5 l3 per kg). virus was not isolated from the animals given 1000 irradiated larvae. typical clinical signs and lesions of ibr developed ... | 1983 | 6306071 |
| cloning and cleavage site mapping of dna from bovine herpesvirus 1 (cooper strain). | sequences representative of most of the bovine herpesvirus 1 (cooper strain) dna were cloned in the plasmid vector pbr322 at the hindiii site. ecori, hpai, and bamhi restriction endonuclease sites were mapped in each of the cloned fragments, and this information was used to construct a restriction endonuclease cleavage site map of the entire viral genome for the four enzymes. | 1983 | 6306279 |
| a comparison of the virulence of three strains of infectious bovine rhinotracheitis virus. | the virulence of three strains of infectious bovine rhinotracheitis (ibr) virus was compared in six-month-old ayrshire-cross calves. the strains were an isolate from a recent severe outbreak of ibr in scotland (strichen strain), the prototype british strain (oxford strain) and a north american isolate (colorado strain). the colorado and strichen strains produced the characteristic clinical signs and pathological lesions of severe ibr three to four days post infection (p.i.). the strichen strain ... | 1983 | 6306899 |
| [evaluation of the specificity of skin allergy tests in cattle with ibr-ipv]. | an allergic and serologic investigation was carried out by the skin allergic test (sat) and the virus neutralization test (vnt) to demonstrate the presence of infectious bovine rhinotracheitis -- infectious pustular vulvovaginitis (ibr-ipv) in cattle divided into three groups according to age, treated with the live attenuated vaccine mk25 against aujeszky's disease. it was found that this vaccine induced the production of specific antibodies against the virus of ibr-ipv, which could be demonstra ... | 1983 | 6306906 |
| [use of nonspecific agents and vaccination in bronchopneumonia prevention in cattle]. | a group of 463 calves, kept under one and the same conditions of tending and feeding, were followed up from the fifteenth day after birth up to one year of age, after treatment by subgroups with a hyperimmune antibovine rabbit serum, biomass of chlorella, a tissue preparation of swine embryos, and vaccines against mucosal diseases and infectious bovine rhinotracheitis. the experiment revealed that those of the calves that were treated with a combination of chlorella biomass and a hyperimmune ant ... | 1983 | 6306907 |
| [humoral immune response of rabbits inoculated with bovine herpes virus type 1. comparison of serum neutralization, complement fixation, immunodiffusion and passive hemagglutination tests]. | | 1983 | 6306956 |
| a study in calves, swine and rabbits of the immunological relationships between infectious bovine rhinotracheitis virus and aujeszky's disease virus. | | 1983 | 6306958 |
| serological and virological response in steers after vaccination with bovine herpesvirus 1. | | 1983 | 6307245 |
| [epizootiological features of infection with infectious bovine rhinotracheitis virus on dairy farms]. | | 1983 | 6308849 |
| [field trials of a number of ibr vaccines in dairy cattle]. | vaccination of ninety-six cows which showed titres of less than or equal to 1:2 on inoculation, using vaccines containing attenuated live ibr virus (tracherine, resbo. ibr pi3, respacine 3) elicited a moderate serological response. inoculation of these vaccines in 192 cows showing titres of greater than or equal to 1:3 on vaccination did not result in a significant increase in titre. inactivated ibr vaccines (iffavax and ibeair h) induced a satisfactory serological response in 140 cows, regardle ... | 1983 | 6308850 |
| [vaccination against ibr: a recommendation for dairy herds]. | in view of the results of previous serological studies on the presence of sn antibodies to ibr virus in a minimum of ten per cent of the herd, the following procedure is suggested: (1) vaccination of serologically negative herds in areas menaced by ibr virus. (2) vaccination of ibr-negative groups of animals in herds in which serologically ibr-positive animals are present. when sampling shows that ibr-negative animals are present in every age group, vaccination of the entire herd should be conte ... | 1983 | 6308851 |
| reactivation and shedding of infectious bovine rhinotracheitis virus caused by 3-methylindole. | | 1983 | 6308882 |
| a mail survey of factors associated with morbidity and mortality in feedlot calves in southwestern ontario. | the design and results of a mail survey of a simple random sample of southwestern ontario feedlot owners are presented. the survey provided general data about management of feedlot calves and the association between a number of factors and disease and/or death rates. the number of calves purchased was related positively, in a linear manner, to mortality and morbidity rates. increased levels of morbidity and mortality were noted when the ration was changed to corn silage from dry-hay within the f ... | 1983 | 6309344 |
| the effect of dose, route and virulence of bovine herpesvirus 1 vaccine on experimental respiratory disease in cattle. | three experiments were conducted with calves in which, following intramuscular or intranasal vaccination with virulent or attenuated bovine herpesvirus 1, calves were protected against bovine herpesvirus 1 -- pasteurella haemolytica challenge. calves receiving low doses of vaccine had lower levels of antibody and greater evidence of virus replication upon challenge than those receiving higher doses. in contrast 11/13 unvaccinated controls had fibrino-purulent pneumonia following challenge. the i ... | 1983 | 6309347 |
| meningoencephalitis caused by ibr virus in calves in argentina. | | 1983 | 6310913 |
| nonspecific suppressive effect of bovine herpesvirus type 1 on bovine leukocyte functions. | the effect of bovine herpesvirus type 1 on the specific and nonspecific immune response of calves was examined. animals with or without prior aerosol exposure to pasteurella haemolytica serotype a1 were aerosol challenged with 10(8) pfu of virus. blood and serum samples were taken before and after virus challenge for determining cell-mediated, humoral, and neutrophil responses. a significant depression of the blastogenic responses to phytohemagglutinin, p. haemolytica, and pasteurella multocida ... | 1983 | 6311742 |
| goat herpesviruses: biological and physicochemical properties. | two herpesvirus isolates from goats are known which cause afflictions of the digestive tract in kids and, in some cases, abortion. an antigenic relationship of these goat herpesviruses with infectious bovine rhinotracheitis/infectious pustular vulvo-vaginitis virus (bovid herpesvirus 1, bhv-1) was reported and because of the species-specific pathogenicity, the goat isolates were named caprine herpesvirus 1. in this report the two isolates are further characterized and compared with bhv-1. althou ... | 1983 | 6311953 |
| analysis of bovine herpes virus-type 1 isolates by restriction endonuclease fingerprinting. | in an effort to determine whether distinct types of bovine herpesvirus 1 are responsible for causing specific syndromes, the polypeptides and dna of 93 bhv 1 isolates from the province of alberta as well as vaccine strains and numerous other canadian, u.s. and european isolates were analyzed by page and restriction endonuclease fingerprinting, respectively. the polypeptide patterns showed only slight variations: only six isolates contained polypeptides that varied from the norm in their molecula ... | 1983 | 6312930 |