TitleAbstractYear(sorted descending)
rous sarcoma in chinese hamsters.a variant of the rous sarcoma virus induced tumors in newborn chinese hamsters within 2 to8 weeks. the tumors grew progressively and sometimes metastasized. they were successfully transplanted in series in syrian hamsters. the chromosomes of the tumors in the chinese hamstersas well as of those transplanted into the syrian hamsters were chinese hamster chromosomes. virus was demonstrated in the chinese hamster tumors by injecting material from the tumors into chickens, where rous sarcomas subseq ...196414150329
infection of mch chinese hamster cells with herpes simplex virus: relation of cell killing to time of division. 196414240415
replication of mengovirus in chinese hamster ovary cells. la-3132-ms. 196414271615
hypoxic cell sensitizers and heavy charged-particle radiations.stationary-phase populations of chinese hamster v-79 cells were irradiated with 250 kv x-rays and the bragg peaks (spread to a width of 4 cm) of energetic he-, c-, ne-, and a-ion beams produced at the 184-inch cyclotron and bevalac at lawrence berkeley laboratory. survival curves were generated with each radiation for cells suspended in air-saturated and nitrogen-saturated medium with and without sensitizer present. the oxygen enhancement ratios (oers) measured for x-rays with 1mm metronidazole ...1964277223
chromosomes of x-ray-induced giant cells in chinese hamster in vitro. 196414254441
chromosomal variability in clonal populations of a chinese hamster cell strain. 196414241786
life cycle analysis of mammalian cells. ii. cells from the chinese hamster ovary grown in suspension culture.a method for life cycle analysis in mammalian cells which utilizes the collection function has been applied to the chinese hamster ovary grown in suspension. the following durations were found for the various parts of the life cycle: s, 4.13 hours; g1, 4.71 hours; g2, 2.81 hours; mitosis, 0.81 hours. the cell has a total generation time of 12.4 hours as opposed to 20.1 hours for the s3 hela cell. however, the relative lengths of each phase of the life cycle are identical within experimental unce ...196414232130
mammalian chromosomes in vitro. 18. dna replication in the chinese hamster.the complete dna replication sequence of the entire complement of chromosomes in the chinese hamster may be studied by using the method of continuous h(3)-thymidine labeling and the method of 5-fluorodeoxyuridine block with h(3)-thymidine pulse labeling as relief. many chromosomes start dna synthesis simultaneously at multiple sites, but the sex chromosomes (the y and the long arm of the x) begin dna replication approximately 4.5 hours later and are the last members of the complement to finish r ...196414228518
lysosomes in chinese hamster fibroblasts in culture. 196414208742
polyploidy induced by x-rays in chinese hamster cells in vitro.the incidence of polyploidy (specifically, in this case, the doubling of the stemline chromosome number) induced by x-rays in cells cultured in vitro is about the same for both "near-diploid" and "near-tetraploid" sublines of the chinese hamster. endoreduplication is a principal cytological mechanism for this form of induced polyploidy.196414163776
recovery following x-irradiation of synchronized chinese hamster cells. 196414201754
restitution of radiation-induced chromosomal damage in chinese hamster cells related to the cell's life cycle. 196414195435
the frequency of sister chromatid exchanges following exposure to varying doses of h3-thymidine or the chinese hamster cell line chef-125, sister chromatid exchanges occurred at a rate of a little higher than one per three chromosomes for each cell cycle. the exchanges were detectable by labeling with h(3)-thymidine and autoradiographic analyses of chromosomes at the second and subsequent metaphases after labeling had occurred. to test the hypothesis that sister chromatid exchanges are caused by radiation, cells were incubated in media with different amounts of h(3)-thymidine. no statistic ...196414153478
mammalian chromosomes in vitro. xvii. idiogram of the chinese hamster.from 67 diploid male chinese hamster cells in vitro, an idiogram was constructed. the chromosomes can be classified into 4 natural groups: group i, 2 pairs of large submetacentrics (1 and 2); group ii, 3 pairs of medium-sized submetacentrics (the sex pair, 4 and 5); group iii, 3 pairs of medium-sized subtelocentrics (6,7, and 8); group iv, 3 pairs of small metacentrics (9,10, and 11). a system of subdividing each chromosome into regions is also suggested.196419291904
life span, tumor incidence, and intercapillary glomerulosclerosis in the chinese hamster (cricetulus griseus) after whole-body and partial-body exposure to x-rays. 196414142190
homogeneity and stability of chromosomes of chinese hamster cells in vitro. 196414165061
a technique for studying the in situ. karyotype of epithelial cells from the cheek pouch of the chinese hamster. 196414161572
gross and chromosomal cytology of virus infected chinese hamster cells. 196313934263
an improved nutrient solution for diploid chinese hamster and human cell lines. 196313952250
cellular alterations in the mch line of chinese hamster cells following infection with herpes simplex virus. 196313952430
the histogenesis of experimentally produced melanotic tumours in the chinese hamster (cricetulus criseus). 196314111612
variations in x-ray response during the division cycle of partially synchronized chinese hamster cells in culture. 196314072031
observations of retinal microaneurysms in a metahypophyseal diabetic chinese hamster. 196314061601
dependence of frequency of x-ray-induced chromosome aberrations on dose rate in the chinese hamster. 196314060651
relative ultraviolet sensitivity of different phases in the cell cycle of chinese hamster cells grown in vitro. 196313955703
albumin replacement by fatty acids in clonal growth of mammalian cells.clonal growth of chinese hamster strain chd-3 cells in a synthetic nutrient mixture supplemented with 10 micrograms of purified fetuin per milliliter exhibits an apparent requirement for serum albumin. the albumin can be replaced by linoleic acid, which occurs as a tightly bound component of most albumin preparations. linolenic acid and corn oil can also replace albumin, while oleic acid and esters of linoleic and linolenic acids cannot.196313952251
mammalian chromosomes in vitro: xvi. analysis of chromosomes breakages in cell population of the chinese hamster. 196314278852
[effects of sodium bromide and caffeine on the induction of pituitary adenomas by estrogen in chinese hamsters]. 196314089279
observation of retinopathy in metahypophyseal diabetic chinese hamsters. 196314090728
prediction of spontaneous hereditary diabetes mellitus in chinese hamsters by means of elevated alpha-2 serum levels. 196313950103
pulpal and periodontal disease in a strain of chinese hamsters with hereditary diabetes mellitus. 196314022075
clonal growth of diploid chinese hamster cells in a synthetic medium supplemented with purified protein fractions. 196213952249
x-ray-induced chromosome aberrations in the corneal epithelium of the chinese hamster.when the corneal epithelium of the chinese hamster is irradiated with ionizing radiation in vivo, a rectilinear relationship is observed between the yield of chromosome aberrations and the dose of x-rays within a dose range of 10 to 150 r. there is no threshold effect for chromosome breakage down to the 10-r level. the mean breakage rate of 0.00352 breaks per cell per roentgen is in very close agreement with the data obtained on other mammalian tissues, both in vitro and in vivo.196217820998
acute x-ray lethality in the chinese hamster after whole-body and partial-body irradiation. 196214022952
radiosensitivity of cells of chinese hamster in vitro in relation to the cell cycle. 196213955320
relationship between large y-chromosome and side-by-side pairing of the xy-bivalent observed in the chinese hamster, cricetus griseus. 196214481405
periodontal pathology in a strain of chinese hamster, cricetulus griseus, with hereditary diabetes mellitus. 196113880291
the evaluation of x-ray-induced chromosome aberrations in cell-cultures of the chinese hamster. 196113901497
spontaneous and x-ray-induced somatic-chromosome aberrations in the chinese hamster. 196113867089
the interaction of mammalian cells with antibodies. i.the single cell plating technique has been applied to quantitation of the reproductive killing of mammalian cells by specific antibodies. this method confirms previous demonstrations by other workers of localization of all the killing activity in the gamma-globulin fraction of specific cell antisera but not of normal sera; the need for complement for the killing action in low doses of antibody and the leakage of cell constituents attending cell killing under these conditions. in concentrations o ...196113730250
chinese-hamster cell strains in vitro:spontaneous chromosome changes and latent polyoma-virus infection. 196113700713
adenocarcinoma of the pancreas in diabetes-prone chinese hamsters. 196114487364
progressive intercapillary glomerulosclerosis in the mouse, rat, and chinese hamster, associated with aging and x-ray exposure. 196013830499
elevated alpha-2-serum proteins as a possible genetic marker in spontaneous hereditary diabetes mellitus of the chinese hamster (cricetulus griseus). 196013708201
radiation response of mammalian cells grown in culture. 1. repair of x-ray damage in surviving chinese hamster cells. 196013726391
asynchronous duplication of chromosomes in cultured cells of chinese hamster.chromosome duplication (dna synthesis) was studied in cultured cells of chinese hamsters by means of autoradiography following thymidine-h(3) incorporation. the technique used was to expose an asynchronously dividing population of rapidly growing cells for a 10 minute interval to a medium with thymidine-h(3). cells were then transferred to a medium with excess unlabeled thymidine. the population was sampled at intervals thereafter and studies made of the frequency of labeled interphases and divi ...196013837165
biochemical studies on the chinese hamster (22 chromosomes) and the syrian hamster (44 chromosomes). 195913653002
further observations on the chromosomes of chinese hamster cells in tissue culture. 195913655062
spontaneous hereditary diabetes mellitus in chinese hamster (cricetulus griseus). 1. pathological findings. 195913645727
[comparative nuclear volumetric investigation in cricetus cricetus, cricetulus barabensis griseus & the presumably tetraploid mesocricetus auratus (gold hamster)]. 195813558423
genetics of somatic mammalian cells. ii. chromosomal constitution of cells in tissue culture.a convenient, reliable method for chromosome delineation of animal cells grown as monolayers on glass has been applied to human, opossum, and chinese hamster cells. tissue cultured cells from 5 different, normal organs of 7 different human subjects uniformly displayed the expected chromosome number of 46 and showed no variations in morphology or number other than the expected sex differences and a small incidence of polyploidy. the chromosomes of normal cells from the american opossum were as un ...195813563760
observations on the chromosomes of chinese hamster cells in tissue culture. 195813576097
the striped-back or chinese hamster, cricetulus griseus. 195813539619
the chinese hamster (cricetulus griseus) as an experimental host for trichinella spiralis. 195713476305
adrenal lipid response in chinese hamsters infected with trichinella spiralis. 195713495461
the cheek pouch of the chinese hamster (cricetulus griseus) for cinephotomicroscopy of blood circulation and tumor growth. 195413174931
the fate of leishmania donovani and leptomonas donovani injected into the peritoneal cavity of chinese hamsters and guinea-pigs. 195114905521
the use of the chinese hamsters (cricetulus griseus) in the study of mycobacterium tuberculosis. i. comparison between the cultural method and animal inoculation for the primary isolation of tubercle bacilli. 195114822071
the use of the chinese hamsters (cricetulus griseus) in the study of mycobacterium tuberculosis. ii. for the differentiation of human and bovine types. 195114831170
synergism between halothane and nitrous oxide in the production of nuclear abnormalities in the dividing fibroblast.when chinese hamster fibroblasts divide in the presence of halothane there is an increased incidence of cells with abnormal nuclei, both in mitosis and in interphase. the authors compared the effects of halothane and nitrous oxide separately and in combination. nitrous oxide, 75 percent, alone had no significant effect compared with controls, less than 1.4 per cent of cells showing abnormalities, while halothane alone had a dose-dependent effect on both phases of the cell cycle. halothane, 1 per ...19511275313
etiology of oroya fever : xi. comparison of bartonella bacilliformis and bartonella muris. cultivation of bacterium murium, n. sp.bartonella muris appeared in the blood of all white rats, wild rats, chinese hamster, and mice, from which the spleen was removed, but did not appear in that of splenectomized monkeys, rabbits, or guinea pigs. it has not been possible to transmit b. muris to normal rats, monkeys, rabbits, or guinea pigs, by intraperitoneal, intradermal, or intravenous injection of blood containing b. muris from splenectomized rats. in two instances an acute orchitis was induced in normal rats by injection direct ...192819869409
catalytic residues and a predicted structure of tetrahydrobiopterin-dependent alkylglycerol mono-oxygenase.alkylglycerol mono-oxygenase (ec forms a third, distinct, class among tetrahydrobiopterin-dependent enzymes in addition to aromatic amino acid hydroxylases and nitric oxide synthases. its protein sequence contains the fatty acid hydroxylase motif, a signature indicative of a di-iron centre, which contains eight conserved histidine residues. membrane enzymes containing this motif, including alkylglycerol mono-oxygenase, are especially labile and so far have not been purified to homogen ...022220568
arf6 targets recycling vesicles to the plasma membrane: insights from an ultrastructural investigation.we have shown previously that the adp-ribosylation factor (arf)-6 gtpase localizes to the plasma membrane and intracellular endosomal compartments. expression of arf6 mutants perturbs endosomal trafficking and the morphology of the peripheral membrane system. however, another study on the distribution of arf6 in subcellular fractions of chinese hamster ovary (cho) cells suggested that arf6 did not localize to endosomes labeled after 10 min of horseradish peroxidase (hrp) uptake, but instead was ...09456320
invertebrate specific d1-like dopamine receptor in control of salivary glands in the black-legged tick ixodes scapularis.the control of tick salivary secretion, which plays a crucial role in compromising the host immune system, involves complex neural mechanisms. dopamine is known to be the most potent activator of salivary secretion, as a paracrine/autocrine factor. we describe the invertebrate-specific d1-like dopamine receptor (invd1l), which is highly expressed in tick salivary glands. the invd1l phylogenic clade was found only in invertebrates, suggesting that this receptor was lost in vertebrates during evol ...024307522
mucopolysaccharidosis type i in 21 czech and slovak patients: mutation analysis suggests a functional importance of c-terminus of the idua protein.mucopolysaccharidosis type i (mps i) is an autosomal recessive lysosomal storage disorder that is caused by a deficiency of the enzyme alpha-l-iduronidase (idua). of the 21 czech and slovak patients who have been diagnosed with mps i in the last 30 years, 16 have a severe clinical presentation (hurler syndrome), 2 less severe manifestations (scheie syndrome), and 3 an intermediate severity (hurler/scheie phenotype). mutation analysis was performed in 20 mps i patients and 39 mutant alleles were ...019396826
antigenotoxic properties of paliurus spina-christi mill fruits and their active compounds.paliurus spina-christi mill. (ps) fruits are widely used for different medical purposes in turkey. like in many medicinal herbs the studies concerning their activity, the activities of ps are also not well clarified. the aim of this study is to evaluate the antigenotoxicity of the compounds isolated and identified from the extracts of ps fruits.028446228
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